{"meta": {"count": 12438, "db_response_time_ms": 194, "page": 1, "per_page": 25, "groups_count": null, "cost_usd": 0.001}, "results": [{"id": "https://openalex.org/W4389474678", "doi": "https://doi.org/10.1007/978-981-99-3110-1_23", "title": "Hematology Analyzers and Reagents", "display_name": "Hematology Analyzers and Reagents", "relevance_score": 347.47418, "publication_year": 2023, "publication_date": "2023-01-01", "ids": {"openalex": "https://openalex.org/W4389474678", "doi": "https://doi.org/10.1007/978-981-99-3110-1_23"}, "language": "en", "primary_location": {"id": "doi:10.1007/978-981-99-3110-1_23", "is_oa": false, "landing_page_url": "https://doi.org/10.1007/978-981-99-3110-1_23", "pdf_url": null, "source": null, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "In Vitro Diagnostic Industry in China", "raw_type": "book-chapter"}, "type": "book-chapter", "indexed_in": ["crossref"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5113066227", "display_name": "Guangna Ma", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210158983", "display_name": "Mindray (China)", "ror": "https://ror.org/04yfe8169", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210158983"]}], "countries": ["CN"], "is_corresponding": true, "raw_author_name": "Guangna Ma", "raw_affiliation_strings": ["Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China"], "affiliations": [{"raw_affiliation_string": "Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China", "institution_ids": ["https://openalex.org/I4210158983"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5028391091", "display_name": "Gengwen Chen", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210158983", "display_name": "Mindray (China)", "ror": "https://ror.org/04yfe8169", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210158983"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Gengwen Chen", "raw_affiliation_strings": ["Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China"], "affiliations": [{"raw_affiliation_string": "Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China", "institution_ids": ["https://openalex.org/I4210158983"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5056380784", "display_name": "Jialin Lin", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210158983", "display_name": "Mindray (China)", "ror": "https://ror.org/04yfe8169", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210158983"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Jialin Lin", "raw_affiliation_strings": ["Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China"], "affiliations": [{"raw_affiliation_string": "Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China", "institution_ids": ["https://openalex.org/I4210158983"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5100533138", "display_name": "Lingyu Bai", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210158983", "display_name": "Mindray (China)", "ror": "https://ror.org/04yfe8169", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210158983"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Lingyu Bai", "raw_affiliation_strings": ["Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China"], "affiliations": [{"raw_affiliation_string": "Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China", "institution_ids": ["https://openalex.org/I4210158983"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5024191579", "display_name": "Biao Wu", "orcid": "https://orcid.org/0000-0001-9229-5894"}, "institutions": [{"id": "https://openalex.org/I4210158983", "display_name": "Mindray (China)", "ror": "https://ror.org/04yfe8169", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210158983"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Biao Wu", "raw_affiliation_strings": ["Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China"], "affiliations": [{"raw_affiliation_string": "Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China", "institution_ids": ["https://openalex.org/I4210158983"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5111810805", "display_name": "Yuxuan Tang", "orcid": "https://orcid.org/0009-0008-9574-0664"}, "institutions": [{"id": "https://openalex.org/I4210096056", "display_name": "Shanghai CASB Biotechnology (China)", "ror": "https://ror.org/00t1pfq43", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210096056"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Yong Tang", "raw_affiliation_strings": ["Maccura Biotechnology Co. Ltd, Chengdu, Sichuan, China"], "affiliations": [{"raw_affiliation_string": "Maccura Biotechnology Co. Ltd, Chengdu, Sichuan, China", "institution_ids": ["https://openalex.org/I4210096056"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5115602489", "display_name": "Yang Yang", "orcid": "https://orcid.org/0000-0002-3217-3243"}, "institutions": [{"id": "https://openalex.org/I4210096056", "display_name": "Shanghai CASB Biotechnology (China)", "ror": "https://ror.org/00t1pfq43", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210096056"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Yang Yang", "raw_affiliation_strings": ["Maccura Biotechnology Co. Ltd, Chengdu, Sichuan, China"], "affiliations": [{"raw_affiliation_string": "Maccura Biotechnology Co. Ltd, Chengdu, Sichuan, China", "institution_ids": ["https://openalex.org/I4210096056"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5101948499", "display_name": "Yu Kang", "orcid": "https://orcid.org/0000-0002-3479-123X"}, "institutions": [{"id": "https://openalex.org/I4210096056", "display_name": "Shanghai CASB Biotechnology (China)", "ror": "https://ror.org/00t1pfq43", "country_code": "CN", "type": "company", "lineage": ["https://openalex.org/I4210096056"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Kang Yu", "raw_affiliation_strings": ["Maccura Biotechnology Co. Ltd, Chengdu, Sichuan, China"], "affiliations": [{"raw_affiliation_string": "Maccura Biotechnology Co. Ltd, Chengdu, Sichuan, China", "institution_ids": ["https://openalex.org/I4210096056"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 8, "corresponding_author_ids": ["https://openalex.org/A5113066227"], "corresponding_institution_ids": ["https://openalex.org/I4210158983"], "apc_list": null, "apc_paid": null, "fwci": 0.4057, "has_fulltext": false, "cited_by_count": 1, "citation_normalized_percentile": {"value": 0.70813779, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 91, "max": 95}, "biblio": {"volume": null, "issue": null, "first_page": "381", "last_page": "399"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.8981000185012817, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, "topics": [{"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.8981000185012817, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T12286", "display_name": "Erythrocyte Function and Pathophysiology", "score": 0.7717000246047974, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12279", "display_name": "Body Composition Measurement Techniques", "score": 0.7168999910354614, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.9766273498535156}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.7071110606193542}, {"id": "https://openalex.org/keywords/colorimetry", "display_name": "Colorimetry", "score": 0.6291689276695251}, {"id": "https://openalex.org/keywords/hemoglobin", "display_name": "Hemoglobin", "score": 0.5489242672920227}, {"id": "https://openalex.org/keywords/spectrum-analyzer", "display_name": "Spectrum analyzer", "score": 0.5274757742881775}, {"id": "https://openalex.org/keywords/platelet", "display_name": "Platelet", "score": 0.46220800280570984}, {"id": "https://openalex.org/keywords/blood-smear", "display_name": "Blood smear", "score": 0.439770370721817}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.4036708474159241}, {"id": "https://openalex.org/keywords/biomedical-engineering", "display_name": "Biomedical engineering", "score": 0.3763768672943115}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.3475528955459595}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.3307010531425476}, {"id": "https://openalex.org/keywords/chromatography", "display_name": "Chromatography", "score": 0.3122718930244446}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.2813491225242615}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.24460190534591675}, {"id": "https://openalex.org/keywords/telecommunications", "display_name": "Telecommunications", "score": 0.08977192640304565}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.9766273498535156}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.7071110606193542}, {"id": "https://openalex.org/C64299311", "wikidata": "https://www.wikidata.org/wiki/Q374535", "display_name": "Colorimetry", "level": 2, "score": 0.6291689276695251}, {"id": "https://openalex.org/C2778917026", "wikidata": "https://www.wikidata.org/wiki/Q43041", "display_name": "Hemoglobin", "level": 2, "score": 0.5489242672920227}, {"id": "https://openalex.org/C158007255", "wikidata": "https://www.wikidata.org/wiki/Q1055222", "display_name": "Spectrum analyzer", "level": 2, "score": 0.5274757742881775}, {"id": "https://openalex.org/C89560881", "wikidata": "https://www.wikidata.org/wiki/Q101026", "display_name": "Platelet", "level": 2, "score": 0.46220800280570984}, {"id": "https://openalex.org/C3017819844", "wikidata": "https://www.wikidata.org/wiki/Q886475", "display_name": "Blood smear", "level": 3, "score": 0.439770370721817}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.4036708474159241}, {"id": "https://openalex.org/C136229726", "wikidata": "https://www.wikidata.org/wiki/Q327092", "display_name": "Biomedical engineering", "level": 1, "score": 0.3763768672943115}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.3475528955459595}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.3307010531425476}, {"id": "https://openalex.org/C43617362", "wikidata": "https://www.wikidata.org/wiki/Q170050", "display_name": "Chromatography", "level": 1, "score": 0.3122718930244446}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.2813491225242615}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.24460190534591675}, {"id": "https://openalex.org/C76155785", "wikidata": "https://www.wikidata.org/wiki/Q418", "display_name": "Telecommunications", "level": 1, "score": 0.08977192640304565}, {"id": "https://openalex.org/C2778048844", "wikidata": "https://www.wikidata.org/wiki/Q12156", "display_name": "Malaria", "level": 2, "score": 0.0}], "mesh": [], "locations_count": 1, "locations": [{"id": "doi:10.1007/978-981-99-3110-1_23", "is_oa": false, "landing_page_url": "https://doi.org/10.1007/978-981-99-3110-1_23", "pdf_url": null, "source": null, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "In Vitro Diagnostic Industry in China", "raw_type": "book-chapter"}], "best_oa_location": null, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 0, "referenced_works": [], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W2367382573", "https://openalex.org/W3114788508", "https://openalex.org/W2364386882", "https://openalex.org/W2352314160", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W2351951261"], "abstract_inverted_index": null, "counts_by_year": [{"year": 2025, "cited_by_count": 1}], "updated_date": "2026-01-25T23:04:38.658462", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W3168097075", "doi": "https://doi.org/10.1002/aisy.202000277", "title": "Artificial\u2010Intelligence\u2010Enabled Reagent\u2010Free Imaging Hematology Analyzer", "display_name": "Artificial\u2010Intelligence\u2010Enabled Reagent\u2010Free Imaging Hematology Analyzer", "relevance_score": 282.41116, "publication_year": 2021, "publication_date": "2021-06-02", "ids": {"openalex": "https://openalex.org/W3168097075", "doi": "https://doi.org/10.1002/aisy.202000277", "mag": "3168097075"}, "language": "en", "primary_location": {"id": "doi:10.1002/aisy.202000277", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/aisy.202000277", "pdf_url": null, "source": {"id": "https://openalex.org/S4210212817", "display_name": "Advanced Intelligent Systems", "issn_l": "2640-4567", "issn": ["2640-4567"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Advanced Intelligent Systems", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "doaj"], "open_access": {"is_oa": true, "oa_status": "gold", "oa_url": "https://doi.org/10.1002/aisy.202000277", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5014493066", "display_name": "Xin Shu", "orcid": "https://orcid.org/0000-0001-9502-9807"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": false, "raw_author_name": "Xin Shu", "raw_affiliation_strings": ["Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": "https://orcid.org/0000-0001-9502-9807", "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5020418389", "display_name": "Sameera Sansare", "orcid": "https://orcid.org/0000-0002-4976-3282"}, "institutions": [{"id": "https://openalex.org/I140172145", "display_name": "University of Connecticut", "ror": "https://ror.org/02der9h97", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I140172145"]}, {"id": "https://openalex.org/I4210101648", "display_name": "Connecticut Children's Medical Center", "ror": "https://ror.org/01a1jjn24", "country_code": "US", "type": "funder", "lineage": ["https://openalex.org/I4210101648"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Sameera Sansare", "raw_affiliation_strings": ["Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "Department of Pharmaceutical Sciences University of Connecticut  Storrs CT 06269 USA", "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA", "Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, 06269 USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "institution_ids": ["https://openalex.org/I4210101648"]}, {"raw_affiliation_string": "Department of Pharmaceutical Sciences University of Connecticut  Storrs CT 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5112574959", "display_name": "Di Jin", "orcid": "https://orcid.org/0009-0001-4646-5220"}, "institutions": [{"id": "https://openalex.org/I63966007", "display_name": "Massachusetts Institute of Technology", "ror": "https://ror.org/042nb2s44", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I63966007"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Di Jin", "raw_affiliation_strings": ["Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology  Cambridge MA 02139 USA", "Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139 USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology  Cambridge MA 02139 USA", "institution_ids": ["https://openalex.org/I63966007"]}, {"raw_affiliation_string": "Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139 USA", "institution_ids": ["https://openalex.org/I63966007"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5027286013", "display_name": "Xiangxiang Zeng", "orcid": "https://orcid.org/0000-0001-6201-0114"}, "institutions": [{"id": "https://openalex.org/I16609230", "display_name": "Hunan University", "ror": "https://ror.org/05htk5m33", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I16609230"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Xiangxiang Zeng", "raw_affiliation_strings": ["School of Information Science and Engineering Hunan University  Changsha 410076 China", "School of Information Science and Engineering, Hunan University, Changsha, 410076 China"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "School of Information Science and Engineering Hunan University  Changsha 410076 China", "institution_ids": ["https://openalex.org/I16609230"]}, {"raw_affiliation_string": "School of Information Science and Engineering, Hunan University, Changsha, 410076 China", "institution_ids": ["https://openalex.org/I16609230"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5066840655", "display_name": "Raymond Kai\u2010Yu Tong", "orcid": "https://orcid.org/0000-0003-4375-653X"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": false, "raw_author_name": "Kai-Yu Tong", "raw_affiliation_strings": ["Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5018663240", "display_name": "Rishikesh Pandey", "orcid": "https://orcid.org/0000-0003-4975-3815"}, "institutions": [{"id": "https://openalex.org/I140172145", "display_name": "University of Connecticut", "ror": "https://ror.org/02der9h97", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I140172145"]}, {"id": "https://openalex.org/I4210101648", "display_name": "Connecticut Children's Medical Center", "ror": "https://ror.org/01a1jjn24", "country_code": "US", "type": "funder", "lineage": ["https://openalex.org/I4210101648"]}], "countries": ["US"], "is_corresponding": true, "raw_author_name": "Rishikesh Pandey", "raw_affiliation_strings": ["Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "Department of Biomedical Engineering University of Connecticut  Storrs CT 06269 USA", "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA", "Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269 USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "institution_ids": ["https://openalex.org/I4210101648"]}, {"raw_affiliation_string": "Department of Biomedical Engineering University of Connecticut  Storrs CT 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5022877503", "display_name": "Renjie Zhou", "orcid": "https://orcid.org/0000-0002-4761-6641"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": true, "raw_author_name": "Renjie Zhou", "raw_affiliation_strings": ["Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Shun Hing Institute of Advanced Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "Shun Hing Institute of Advanced Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": "https://orcid.org/0000-0002-4761-6641", "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Shun Hing Institute of Advanced Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Shun Hing Institute of Advanced Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}], "institutions": [], "countries_distinct_count": 3, "institutions_distinct_count": 7, "corresponding_author_ids": ["https://openalex.org/A5018663240", "https://openalex.org/A5022877503"], "corresponding_institution_ids": ["https://openalex.org/I140172145", "https://openalex.org/I177725633", "https://openalex.org/I4210101648"], "apc_list": {"value": 2750, "currency": "USD", "value_usd": 2750}, "apc_paid": {"value": 2750, "currency": "USD", "value_usd": 2750}, "fwci": 2.2444, "has_fulltext": false, "cited_by_count": 19, "citation_normalized_percentile": {"value": 0.88238928, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 96, "max": 98}, "biblio": {"volume": "3", "issue": "8", "first_page": null, "last_page": null}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11897", "display_name": "Digital Holography and Microscopy", "score": 0.9994000196456909, "subfield": {"id": "https://openalex.org/subfields/3107", "display_name": "Atomic and Molecular Physics, and Optics"}, "field": {"id": "https://openalex.org/fields/31", "display_name": "Physics and Astronomy"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, "topics": [{"id": "https://openalex.org/T11897", "display_name": "Digital Holography and Microscopy", "score": 0.9994000196456909, "subfield": {"id": "https://openalex.org/subfields/3107", "display_name": "Atomic and Molecular Physics, and Optics"}, "field": {"id": "https://openalex.org/fields/31", "display_name": "Physics and Astronomy"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T12859", "display_name": "Cell Image Analysis Techniques", "score": 0.9958999752998352, "subfield": {"id": "https://openalex.org/subfields/1304", "display_name": "Biophysics"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T13114", "display_name": "Image Processing Techniques and Applications", "score": 0.9922999739646912, "subfield": {"id": "https://openalex.org/subfields/2214", "display_name": "Media Technology"}, "field": {"id": "https://openalex.org/fields/22", "display_name": "Engineering"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.7672621607780457}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.6967876553535461}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.47595664858818054}, {"id": "https://openalex.org/keywords/artificial-intelligence", "display_name": "Artificial intelligence", "score": 0.46477487683296204}, {"id": "https://openalex.org/keywords/blood-smear", "display_name": "Blood smear", "score": 0.4327501356601715}, {"id": "https://openalex.org/keywords/pattern-recognition", "display_name": "Pattern recognition (psychology)", "score": 0.3748970627784729}, {"id": "https://openalex.org/keywords/biomedical-engineering", "display_name": "Biomedical engineering", "score": 0.37300536036491394}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.37285304069519043}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.34729909896850586}, {"id": "https://openalex.org/keywords/medical-physics", "display_name": "Medical physics", "score": 0.3274271488189697}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.304379403591156}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.7672621607780457}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.6967876553535461}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.47595664858818054}, {"id": "https://openalex.org/C154945302", "wikidata": "https://www.wikidata.org/wiki/Q11660", "display_name": "Artificial intelligence", "level": 1, "score": 0.46477487683296204}, {"id": "https://openalex.org/C3017819844", "wikidata": "https://www.wikidata.org/wiki/Q886475", "display_name": "Blood smear", "level": 3, "score": 0.4327501356601715}, {"id": "https://openalex.org/C153180895", "wikidata": "https://www.wikidata.org/wiki/Q7148389", "display_name": "Pattern recognition (psychology)", "level": 2, "score": 0.3748970627784729}, {"id": "https://openalex.org/C136229726", "wikidata": "https://www.wikidata.org/wiki/Q327092", "display_name": "Biomedical engineering", "level": 1, "score": 0.37300536036491394}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.37285304069519043}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.34729909896850586}, {"id": "https://openalex.org/C19527891", "wikidata": "https://www.wikidata.org/wiki/Q1120908", "display_name": "Medical physics", "level": 1, "score": 0.3274271488189697}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.304379403591156}, {"id": "https://openalex.org/C2778048844", "wikidata": "https://www.wikidata.org/wiki/Q12156", "display_name": "Malaria", "level": 2, "score": 0.0}], "mesh": [], "locations_count": 2, "locations": [{"id": "doi:10.1002/aisy.202000277", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/aisy.202000277", "pdf_url": null, "source": {"id": "https://openalex.org/S4210212817", "display_name": "Advanced Intelligent Systems", "issn_l": "2640-4567", "issn": ["2640-4567"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Advanced Intelligent Systems", "raw_type": "journal-article"}, {"id": "pmh:oai:doaj.org/article:eed757e6664e4489bbc5199fc513ad70", "is_oa": true, "landing_page_url": "https://doaj.org/article/eed757e6664e4489bbc5199fc513ad70", "pdf_url": null, "source": {"id": "https://openalex.org/S4306401280", "display_name": "DOAJ (DOAJ: Directory of Open Access Journals)", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "repository"}, "license": "cc-by-sa", "license_id": "https://openalex.org/licenses/cc-by-sa", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "Advanced Intelligent Systems, Vol 3, Iss 8, Pp n/a-n/a (2021)", "raw_type": "article"}], "best_oa_location": {"id": "doi:10.1002/aisy.202000277", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/aisy.202000277", "pdf_url": null, "source": {"id": "https://openalex.org/S4210212817", "display_name": "Advanced Intelligent Systems", "issn_l": "2640-4567", "issn": ["2640-4567"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Advanced Intelligent Systems", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [{"id": "https://openalex.org/G1545141280", "display_name": null, "funder_award_id": "BME-p3-18", "funder_id": "https://openalex.org/F4320335138", "funder_display_name": "Shun Hing Institute of Advanced Engineering"}, {"id": "https://openalex.org/G7607394451", "display_name": null, "funder_award_id": "CM/CT/CF/CIA/0688/19ay", "funder_id": "https://openalex.org/F4320320904", "funder_display_name": "Croucher Foundation"}], "funders": [{"id": "https://openalex.org/F4320320904", "display_name": "Croucher Foundation", "ror": "https://ror.org/04741mc34"}, {"id": "https://openalex.org/F4320335138", "display_name": "Shun Hing Institute of Advanced Engineering", "ror": "https://ror.org/00t33hh48"}], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 63, "referenced_works": ["https://openalex.org/W183625566", "https://openalex.org/W1541288193", "https://openalex.org/W1588610091", "https://openalex.org/W1589378501", "https://openalex.org/W1966716734", "https://openalex.org/W1994616650", "https://openalex.org/W2003824127", "https://openalex.org/W2004908285", "https://openalex.org/W2045559201", "https://openalex.org/W2047602908", "https://openalex.org/W2055129569", "https://openalex.org/W2071843907", "https://openalex.org/W2072888577", "https://openalex.org/W2082485604", "https://openalex.org/W2113821521", "https://openalex.org/W2122796192", "https://openalex.org/W2124677456", "https://openalex.org/W2126078440", "https://openalex.org/W2135241616", "https://openalex.org/W2164536584", "https://openalex.org/W2187089797", "https://openalex.org/W2189329705", "https://openalex.org/W2271268216", "https://openalex.org/W2302517508", "https://openalex.org/W2337133817", "https://openalex.org/W2485100451", "https://openalex.org/W2533732984", "https://openalex.org/W2553655246", "https://openalex.org/W2580767461", "https://openalex.org/W2581135911", "https://openalex.org/W2589934064", "https://openalex.org/W2609549573", "https://openalex.org/W2742397434", "https://openalex.org/W2755327666", "https://openalex.org/W2793577218", "https://openalex.org/W2835530235", "https://openalex.org/W2884160046", "https://openalex.org/W2892479404", "https://openalex.org/W2897592759", "https://openalex.org/W2901331516", "https://openalex.org/W2904591139", "https://openalex.org/W2914505174", "https://openalex.org/W2914686968", "https://openalex.org/W2942357918", "https://openalex.org/W2946363866", "https://openalex.org/W2949887768", "https://openalex.org/W2951939591", "https://openalex.org/W2953247668", "https://openalex.org/W2954503967", "https://openalex.org/W2955738428", "https://openalex.org/W2963444747", "https://openalex.org/W2964299526", "https://openalex.org/W2979529263", "https://openalex.org/W3007823945", "https://openalex.org/W3021344117", "https://openalex.org/W3023060302", "https://openalex.org/W3025063365", "https://openalex.org/W3033022222", "https://openalex.org/W3036529978", "https://openalex.org/W3041589802", "https://openalex.org/W3084552371", "https://openalex.org/W4212863985", "https://openalex.org/W4313383245"], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W3114788508", "https://openalex.org/W2352314160", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W1601719760", "https://openalex.org/W2359341290", "https://openalex.org/W2351951261"], "abstract_inverted_index": {"Leukocyte": [0], "differential": [1], "test": [2, 120], "is": [3, 35, 49, 85, 122, 125, 147], "a": [4, 21, 53, 66, 117], "widely": [5], "carried": [6], "out": [7], "clinical": [8], "procedure": [9], "for": [10, 162], "screening": [11, 165], "infectious": [12, 167], "diseases.": [13, 168], "Existing": [14], "hematology": [15, 31, 110], "analyzers": [16], "require": [17], "labor\u2010intensive": [18], "work": [19], "and": [20, 90, 96, 124, 138, 150], "panel": [22], "of": [23, 42, 61, 107, 114, 142, 166], "expensive": [24], "reagents.": [25], "Herein,": [26], "an": [27], "artificial\u2010intelligence\u2010enabled": [28], "reagent\u2010free": [29], "imaging": [30], "analyzer": [32], "(AIRFIHA)": [33], "modality": [34], "reported": [36], "that": [37], "can": [38, 151], "accurately": [39], "classify": [40], "subpopulations": [41], "leukocytes": [43, 63], "with": [44], "minimal": [45], "sample": [46], "preparation.": [47], "AIRFIHA": [48, 115, 146], "realized": [50], "through": [51], "training": [52], "two\u2010step": [54], "residual": [55], "neural": [56], "network": [57], "using": [58], "label\u2010free": [59], "images": [60], "isolated": [62], "acquired": [64], "from": [65], "custom\u2010built": [67], "quantitative": [68, 78], "phase": [69, 79], "microscope.": [70], "By": [71], "leveraging": [72], "the": [73, 104, 163], "rich": [74], "information": [75], "contained": [76], "in": [77, 87, 116, 155], "images,": [80], "not": [81], "only": [82], "high": [83], "accuracy": [84, 106], "achieved": [86], "differentiating": [88], "B": [89], "T": [91, 98], "lymphocytes,": [92], "but": [93], "also": [94, 152], "CD4": [95], "CD8": [97], "cells": [99], "are": [100], "classified,": [101], "therefore": [102], "outperforming": [103], "classification": [105], "most": [108], "current": [109], "analyzers.": [111], "The": [112], "performance": [113], "randomly": [118], "selected": [119], "set": [121], "validated": [123], "cross\u2010validated": [126], "across": [127], "all": [128], "blood": [129], "donors.": [130], "Due": [131], "to": [132], "its": [133], "easy": [134], "operation,": [135], "low": [136], "cost,": [137], "accurate": [139], "discerning": [140], "capability": [141], "complex": [143], "leukocyte": [144], "subpopulations,": [145], "clinically": [148], "translatable": [149], "be": [153], "deployed": [154], "resource\u2010limited": [156], "settings,": [157], "e.g.,": [158], "during": [159], "pandemic": [160], "situations": [161], "rapid": [164]}, "counts_by_year": [{"year": 2026, "cited_by_count": 1}, {"year": 2025, "cited_by_count": 3}, {"year": 2024, "cited_by_count": 4}, {"year": 2023, "cited_by_count": 4}, {"year": 2022, "cited_by_count": 3}, {"year": 2021, "cited_by_count": 4}], "updated_date": "2026-05-06T08:25:59.206177", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W3113314474", "doi": "https://doi.org/10.22541/au.163578446.63711797/v1", "title": "Artificial\u00a0 Intelligence Enabled Reagent-free Imaging Hematology Analyzer\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0", "display_name": "Artificial\u00a0 Intelligence Enabled Reagent-free Imaging Hematology Analyzer\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0", "relevance_score": 171.48257, "publication_year": 2021, "publication_date": "2021-11-01", "ids": {"openalex": "https://openalex.org/W3113314474", "doi": "https://doi.org/10.22541/au.163578446.63711797/v1", "mag": "3113314474"}, "language": "en", "primary_location": {"id": "doi:10.22541/au.163578446.63711797/v1", "is_oa": true, "landing_page_url": "https://doi.org/10.22541/au.163578446.63711797/v1", "pdf_url": "https://www.authorea.com/doi/pdf/10.22541/au.163578446.63711797", "source": null, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "acceptedVersion", "is_accepted": true, "is_published": false, "raw_source_name": "Authorea, Inc.", "raw_type": "posted-content"}, "type": "preprint", "indexed_in": ["crossref"], "open_access": {"is_oa": true, "oa_status": "gold", "oa_url": "https://www.authorea.com/doi/pdf/10.22541/au.163578446.63711797", "any_repository_has_fulltext": null}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5014493066", "display_name": "Xin Shu", "orcid": "https://orcid.org/0000-0001-9502-9807"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": true, "raw_author_name": "Xin Shu", "raw_affiliation_strings": ["Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": "https://orcid.org/0000-0001-9502-9807", "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5020418389", "display_name": "Sameera Sansare", "orcid": "https://orcid.org/0000-0002-4976-3282"}, "institutions": [{"id": "https://openalex.org/I140172145", "display_name": "University of Connecticut", "ror": "https://ror.org/02der9h97", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I140172145"]}, {"id": "https://openalex.org/I4210101648", "display_name": "Connecticut Children's Medical Center", "ror": "https://ror.org/01a1jjn24", "country_code": "US", "type": "funder", "lineage": ["https://openalex.org/I4210101648"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Sameera Sansare", "raw_affiliation_strings": ["Connecticut Children\u2019s Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA", "Department of Pharmaceutical Sciences, University of Connecticut Storrs, Connecticut, 06269, USA", "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Connecticut Children\u2019s Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Department of Pharmaceutical Sciences, University of Connecticut Storrs, Connecticut, 06269, USA", "institution_ids": ["https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5112574959", "display_name": "Di Jin", "orcid": "https://orcid.org/0009-0001-4646-5220"}, "institutions": [{"id": "https://openalex.org/I63966007", "display_name": "Massachusetts Institute of Technology", "ror": "https://ror.org/042nb2s44", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I63966007"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Di Jin", "raw_affiliation_strings": ["Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology Cambridge, Massachusetts, 02139, USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology Cambridge, Massachusetts, 02139, USA", "institution_ids": ["https://openalex.org/I63966007"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5040485508", "display_name": "Xiangxiang Zhang", "orcid": "https://orcid.org/0000-0002-4927-2889"}, "institutions": [{"id": "https://openalex.org/I16609230", "display_name": "Hunan University", "ror": "https://ror.org/05htk5m33", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I16609230"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Xiangxiang Zhang", "raw_affiliation_strings": ["School of Information Science and Engineering, Hunan University, Changsha, 410076, China"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "School of Information Science and Engineering, Hunan University, Changsha, 410076, China", "institution_ids": ["https://openalex.org/I16609230"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5066840655", "display_name": "Raymond Kai\u2010Yu Tong", "orcid": "https://orcid.org/0000-0003-4375-653X"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": false, "raw_author_name": "Kai-Yu Tong", "raw_affiliation_strings": ["Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5018663240", "display_name": "Rishikesh Pandey", "orcid": "https://orcid.org/0000-0003-4975-3815"}, "institutions": [{"id": "https://openalex.org/I140172145", "display_name": "University of Connecticut", "ror": "https://ror.org/02der9h97", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I140172145"]}, {"id": "https://openalex.org/I4210101648", "display_name": "Connecticut Children's Medical Center", "ror": "https://ror.org/01a1jjn24", "country_code": "US", "type": "funder", "lineage": ["https://openalex.org/I4210101648"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Rishikesh Pandey", "raw_affiliation_strings": ["Connecticut Children\u2019s Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA", "Department of Biomedical Engineering, University of Connecticut, Storrs, Connecticut, 06269, USA", "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Connecticut Children\u2019s Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, University of Connecticut, Storrs, Connecticut, 06269, USA", "institution_ids": ["https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, Connecticut, 06032, USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5022877503", "display_name": "Renjie Zhou", "orcid": "https://orcid.org/0000-0002-4761-6641"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": false, "raw_author_name": "Renjie Zhou", "raw_affiliation_strings": ["Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "Shun Hing Institute of Advanced Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Shun Hing Institute of Advanced Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}], "institutions": [], "countries_distinct_count": 3, "institutions_distinct_count": 7, "corresponding_author_ids": ["https://openalex.org/A5014493066"], "corresponding_institution_ids": ["https://openalex.org/I177725633"], "apc_list": null, "apc_paid": null, "fwci": 0.748, "has_fulltext": true, "cited_by_count": 5, "citation_normalized_percentile": {"value": 0.695875, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 90, "max": 96}, "biblio": {"volume": null, "issue": null, "first_page": null, "last_page": null}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11897", "display_name": "Digital Holography and Microscopy", "score": 0.9979000091552734, "subfield": {"id": "https://openalex.org/subfields/3107", "display_name": "Atomic and Molecular Physics, and Optics"}, "field": {"id": "https://openalex.org/fields/31", "display_name": "Physics and Astronomy"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, "topics": [{"id": "https://openalex.org/T11897", "display_name": "Digital Holography and Microscopy", "score": 0.9979000091552734, "subfield": {"id": "https://openalex.org/subfields/3107", "display_name": "Atomic and Molecular Physics, and Optics"}, "field": {"id": "https://openalex.org/fields/31", "display_name": "Physics and Astronomy"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.9962000250816345, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T12859", "display_name": "Cell Image Analysis Techniques", "score": 0.9934999942779541, "subfield": {"id": "https://openalex.org/subfields/1304", "display_name": "Biophysics"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.7811009287834167}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.7005890607833862}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.47705283761024475}, {"id": "https://openalex.org/keywords/artificial-intelligence", "display_name": "Artificial intelligence", "score": 0.4395093619823456}, {"id": "https://openalex.org/keywords/blood-smear", "display_name": "Blood smear", "score": 0.42907002568244934}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.39886778593063354}, {"id": "https://openalex.org/keywords/biomedical-engineering", "display_name": "Biomedical engineering", "score": 0.35318875312805176}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.3379083573818207}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.3238053321838379}, {"id": "https://openalex.org/keywords/medical-physics", "display_name": "Medical physics", "score": 0.3235969543457031}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.7811009287834167}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.7005890607833862}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.47705283761024475}, {"id": "https://openalex.org/C154945302", "wikidata": "https://www.wikidata.org/wiki/Q11660", "display_name": "Artificial intelligence", "level": 1, "score": 0.4395093619823456}, {"id": "https://openalex.org/C3017819844", "wikidata": "https://www.wikidata.org/wiki/Q886475", "display_name": "Blood smear", "level": 3, "score": 0.42907002568244934}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.39886778593063354}, {"id": "https://openalex.org/C136229726", "wikidata": "https://www.wikidata.org/wiki/Q327092", "display_name": "Biomedical engineering", "level": 1, "score": 0.35318875312805176}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.3379083573818207}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.3238053321838379}, {"id": "https://openalex.org/C19527891", "wikidata": "https://www.wikidata.org/wiki/Q1120908", "display_name": "Medical physics", "level": 1, "score": 0.3235969543457031}, {"id": "https://openalex.org/C2778048844", "wikidata": "https://www.wikidata.org/wiki/Q12156", "display_name": "Malaria", "level": 2, "score": 0.0}], "mesh": [], "locations_count": 1, "locations": [{"id": "doi:10.22541/au.163578446.63711797/v1", "is_oa": true, "landing_page_url": "https://doi.org/10.22541/au.163578446.63711797/v1", "pdf_url": "https://www.authorea.com/doi/pdf/10.22541/au.163578446.63711797", "source": null, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "acceptedVersion", "is_accepted": true, "is_published": false, "raw_source_name": "Authorea, Inc.", "raw_type": "posted-content"}], "best_oa_location": {"id": "doi:10.22541/au.163578446.63711797/v1", "is_oa": true, "landing_page_url": "https://doi.org/10.22541/au.163578446.63711797/v1", "pdf_url": "https://www.authorea.com/doi/pdf/10.22541/au.163578446.63711797", "source": null, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "acceptedVersion", "is_accepted": true, "is_published": false, "raw_source_name": "Authorea, Inc.", "raw_type": "posted-content"}, "sustainable_development_goals": [], "awards": [{"id": "https://openalex.org/G1545141280", "display_name": null, "funder_award_id": "BME-p3-18", "funder_id": "https://openalex.org/F4320335138", "funder_display_name": "Shun Hing Institute of Advanced Engineering"}, {"id": "https://openalex.org/G3945117761", "display_name": null, "funder_award_id": "ITS/394/17", "funder_id": "https://openalex.org/F4320321920", "funder_display_name": "Innovation and Technology Commission"}, {"id": "https://openalex.org/G7607394451", "display_name": null, "funder_award_id": "CM/CT/CF/CIA/0688/19ay", "funder_id": "https://openalex.org/F4320320904", "funder_display_name": "Croucher Foundation"}], "funders": [{"id": "https://openalex.org/F4320320904", "display_name": "Croucher Foundation", "ror": "https://ror.org/04741mc34"}, {"id": "https://openalex.org/F4320321920", "display_name": "Innovation and Technology Commission", "ror": "https://ror.org/04vf9tr09"}, {"id": "https://openalex.org/F4320322942", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48"}, {"id": "https://openalex.org/F4320335138", "display_name": "Shun Hing Institute of Advanced Engineering", "ror": "https://ror.org/00t33hh48"}], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W3113314474.pdf", "grobid_xml": "https://content.openalex.org/works/W3113314474.grobid-xml"}, "referenced_works_count": 80, "referenced_works": ["https://openalex.org/W46659105", "https://openalex.org/W183625566", "https://openalex.org/W1522301498", "https://openalex.org/W1665214252", "https://openalex.org/W1686810756", "https://openalex.org/W1836465849", "https://openalex.org/W1966716734", "https://openalex.org/W1983623279", "https://openalex.org/W1994616650", "https://openalex.org/W1997490042", "https://openalex.org/W2003824127", "https://openalex.org/W2004908285", "https://openalex.org/W2045559201", "https://openalex.org/W2047602908", "https://openalex.org/W2055129569", "https://openalex.org/W2071128523", "https://openalex.org/W2071843907", "https://openalex.org/W2072888577", "https://openalex.org/W2082485604", "https://openalex.org/W2097117768", "https://openalex.org/W2113821521", "https://openalex.org/W2122796192", "https://openalex.org/W2124677456", "https://openalex.org/W2126078440", "https://openalex.org/W2135241616", "https://openalex.org/W2164536584", "https://openalex.org/W2187089797", "https://openalex.org/W2189329705", "https://openalex.org/W2194775991", "https://openalex.org/W2271268216", "https://openalex.org/W2302255633", "https://openalex.org/W2302517508", "https://openalex.org/W2337133817", "https://openalex.org/W2485100451", "https://openalex.org/W2505733783", "https://openalex.org/W2533732984", "https://openalex.org/W2553655246", "https://openalex.org/W2581135911", "https://openalex.org/W2589934064", "https://openalex.org/W2609549573", "https://openalex.org/W2754511756", "https://openalex.org/W2755327666", "https://openalex.org/W2758460571", "https://openalex.org/W2793577218", "https://openalex.org/W2806631017", "https://openalex.org/W2835530235", "https://openalex.org/W2884058418", "https://openalex.org/W2884160046", "https://openalex.org/W2892479404", "https://openalex.org/W2897592759", "https://openalex.org/W2901331516", "https://openalex.org/W2903209462", "https://openalex.org/W2904591139", "https://openalex.org/W2914505174", "https://openalex.org/W2914686968", "https://openalex.org/W2942357918", "https://openalex.org/W2946363866", "https://openalex.org/W2949887768", "https://openalex.org/W2952927792", "https://openalex.org/W2953247668", "https://openalex.org/W2954503967", "https://openalex.org/W2955738428", "https://openalex.org/W2963444747", "https://openalex.org/W2964299526", "https://openalex.org/W2979529263", "https://openalex.org/W3007823945", "https://openalex.org/W3023060302", "https://openalex.org/W3025063365", "https://openalex.org/W3033022222", "https://openalex.org/W3036529978", "https://openalex.org/W3041589802", "https://openalex.org/W3084552371", "https://openalex.org/W3134574530", "https://openalex.org/W4212863985", "https://openalex.org/W4243230356", "https://openalex.org/W4246623349", "https://openalex.org/W4252441098", "https://openalex.org/W4309647527", "https://openalex.org/W4313383245", "https://openalex.org/W4406584289"], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W3114788508", "https://openalex.org/W2352314160", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W1601719760", "https://openalex.org/W2359341290", "https://openalex.org/W2351951261"], "abstract_inverted_index": {"Leukocyte": [0], "differential": [1], "test": [2, 120], "is": [3, 49, 147], "a": [4, 20, 53, 66, 117], "widely": [5], "performed": [6], "clinical": [7], "procedure": [8], "for": [9, 162], "screening": [10, 165], "infectious": [11, 167], "diseases.": [12, 168], "Existing": [13], "hematology": [14, 33, 108], "analyzers": [15], "require": [16], "labor-intensive": [17], "work": [18], "and": [19, 90, 97, 122, 136, 150], "panel": [21], "of": [22, 42, 61, 105, 114, 140, 166], "expensive": [23], "reagents.": [24], "Here": [25], "we": [26, 81, 144], "report": [27], "an": [28], "artificial-intelligence": [29], "enabled": [30], "reagent-free": [31], "imaging": [32], "analyzer": [34], "(AIRFIHA)": [35], "modality": [36], "that": [37], "can": [38, 151], "accurately": [39], "classify": [40], "subpopulations": [41], "leukocytes": [43, 63], "with": [44], "minimal": [45], "sample": [46], "preparation.": [47], "AIRFIHA": [48, 115, 146], "realized": [50], "through": [51], "training": [52], "two-step": [54], "residual": [55], "neural": [56], "network": [57], "using": [58], "label-free": [59], "images": [60], "isolated": [62], "acquired": [64], "from": [65], "custom-built": [67], "quantitative": [68, 78], "phase": [69, 79], "microscope.": [70], "By": [71], "leveraging": [72], "the": [73, 102, 112, 163], "rich": [74], "information": [75], "contained": [76], "in": [77, 87, 116, 155], "images,": [80], "not": [82], "only": [83], "achieved": [84], "high": [85], "accuracy": [86, 104], "differentiating": [88], "B": [89], "T": [91], "lymphocytes,": [92], "but": [93], "also": [94, 152], "classified": [95], "CD4": [96], "CD8": [98], "cells,": [99], "therefore": [100], "outperforming": [101], "classification": [103], "most": [106], "current": [107], "analyzers.": [109], "We": [110], "validated": [111], "performance": [113], "randomly": [118], "selected": [119], "set": [121], "cross-validated": [123], "it": [124], "across": [125], "all": [126], "blood": [127], "donors.": [128], "Owing": [129], "to": [130], "its": [131], "easy": [132], "operation,": [133], "low": [134], "cost,": [135], "accurate": [137], "discerning": [138], "capability": [139], "complex": [141], "leukocyte": [142], "subpopulations,": [143], "envision": [145], "clinically": [148], "translatable": [149], "be": [153], "deployed": [154], "resource-limited": [156], "settings,": [157], "e.g.,": [158], "during": [159], "pandemic": [160], "situations": [161], "rapid": [164], "Corresponding": [169], "author(s)": [170], "Email:": [171], "rjzhou@cuhk.edu.hk": [172], ",": [173], "rishikesh.pandey@uconn.edu": [174]}, "counts_by_year": [{"year": 2023, "cited_by_count": 2}, {"year": 2022, "cited_by_count": 1}, {"year": 2021, "cited_by_count": 2}], "updated_date": "2026-03-25T13:04:00.132906", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W134541326", "doi": "https://doi.org/10.1093/ajcp/111.3.387", "title": "Evaluation of a New Reagent for Preserving Fresh Blood Samples and Its Potential Usefulness for Internal Quality Controls of Multichannel Hematology Analyzers", "display_name": "Evaluation of a New Reagent for Preserving Fresh Blood Samples and Its Potential Usefulness for Internal Quality Controls of Multichannel Hematology Analyzers", "relevance_score": 162.51085, "publication_year": 1999, "publication_date": "1999-03-01", "ids": {"openalex": "https://openalex.org/W134541326", "doi": "https://doi.org/10.1093/ajcp/111.3.387", "mag": "134541326", "pmid": "https://pubmed.ncbi.nlm.nih.gov/10078115"}, "language": "en", "primary_location": {"id": "doi:10.1093/ajcp/111.3.387", "is_oa": false, "landing_page_url": "https://doi.org/10.1093/ajcp/111.3.387", "pdf_url": null, "source": {"id": "https://openalex.org/S15871148", "display_name": "American Journal of Clinical Pathology", "issn_l": "0002-9173", "issn": ["0002-9173", "1943-7722"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310311648", "host_organization_name": "Oxford University Press", "host_organization_lineage": ["https://openalex.org/P4310311648", "https://openalex.org/P4310311647"], "host_organization_lineage_names": ["Oxford University Press", "University of Oxford"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Clinical Pathology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5023667543", "display_name": "W. Springer", "orcid": null}, "institutions": [{"id": "https://openalex.org/I135140700", "display_name": "University of Bonn", "ror": "https://ror.org/041nas322", "country_code": "DE", "type": "education", "lineage": ["https://openalex.org/I135140700"]}], "countries": ["DE"], "is_corresponding": true, "raw_author_name": "Wolfram Springer", "raw_affiliation_strings": ["Department of Clinical Biochemistry, University of Bonn, Germany"], "affiliations": [{"raw_affiliation_string": "Department of Clinical Biochemistry, University of Bonn, Germany", "institution_ids": ["https://openalex.org/I135140700"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5072912359", "display_name": "W. Prohaska", "orcid": null}, "institutions": [{"id": "https://openalex.org/I904495901", "display_name": "Ruhr University Bochum", "ror": "https://ror.org/04tsk2644", "country_code": "DE", "type": "education", "lineage": ["https://openalex.org/I904495901"]}, {"id": "https://openalex.org/I2800536013", "display_name": "Heart and Diabetes Center North Rhine-Westphalia", "ror": "https://ror.org/02wndzd81", "country_code": "DE", "type": "healthcare", "lineage": ["https://openalex.org/I2799784675", "https://openalex.org/I2800536013"]}], "countries": ["DE"], "is_corresponding": false, "raw_author_name": "Wolfgang Prohaska", "raw_affiliation_strings": ["Institute of Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine Westphalia, Ruhr-University Bochum, Bad Oeynhausen, Germany", "Institute of Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University, Bochum, Bad Oeynhausen, Germany"], "affiliations": [{"raw_affiliation_string": "Institute of Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine Westphalia, Ruhr-University Bochum, Bad Oeynhausen, Germany", "institution_ids": []}, {"raw_affiliation_string": "Institute of Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University, Bochum, Bad Oeynhausen, Germany", "institution_ids": ["https://openalex.org/I2800536013", "https://openalex.org/I904495901"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5073072859", "display_name": "J. Neukammer", "orcid": "https://orcid.org/0000-0003-4413-3254"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "J\u00f6rg Neukammer", "raw_affiliation_strings": ["Institute of Physikalisch-Technische Bundesanstalt, Berlin-Charlottenburg, Germany"], "affiliations": [{"raw_affiliation_string": "Institute of Physikalisch-Technische Bundesanstalt, Berlin-Charlottenburg, Germany", "institution_ids": []}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5005050794", "display_name": "Andreas H\u00f6pe", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Andreas H\u00f6pe", "raw_affiliation_strings": ["Institute of Physikalisch-Technische Bundesanstalt, Berlin-Charlottenburg, Germany"], "affiliations": [{"raw_affiliation_string": "Institute of Physikalisch-Technische Bundesanstalt, Berlin-Charlottenburg, Germany", "institution_ids": []}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5024287077", "display_name": "Alexander von Ruecker", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Alexander von Ruecker", "raw_affiliation_strings": ["From the Department of Clinical Biochemistry, University of Bonn, Bonn, Germany"], "affiliations": [{"raw_affiliation_string": "From the Department of Clinical Biochemistry, University of Bonn, Bonn, Germany", "institution_ids": []}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 5, "corresponding_author_ids": ["https://openalex.org/A5023667543"], "corresponding_institution_ids": ["https://openalex.org/I135140700"], "apc_list": {"value": 4440, "currency": "USD", "value_usd": 4440}, "apc_paid": null, "fwci": 0.1669, "has_fulltext": false, "cited_by_count": 11, "citation_normalized_percentile": {"value": 0.46362113, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 94}, "biblio": {"volume": "111", "issue": "3", "first_page": "387", "last_page": "396"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9995999932289124, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9995999932289124, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.925000011920929, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematocrit", "display_name": "Hematocrit", "score": 0.8456312417984009}, {"id": "https://openalex.org/keywords/mean-corpuscular-volume", "display_name": "Mean corpuscular volume", "score": 0.6537782549858093}, {"id": "https://openalex.org/keywords/hemoglobin", "display_name": "Hemoglobin", "score": 0.6400008797645569}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.6073914170265198}, {"id": "https://openalex.org/keywords/whole-blood", "display_name": "Whole blood", "score": 0.6027527451515198}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.5456727743148804}, {"id": "https://openalex.org/keywords/serial-dilution", "display_name": "Serial dilution", "score": 0.49667173624038696}, {"id": "https://openalex.org/keywords/analyte", "display_name": "Analyte", "score": 0.49512234330177307}, {"id": "https://openalex.org/keywords/blood-volume", "display_name": "Blood volume", "score": 0.46333515644073486}, {"id": "https://openalex.org/keywords/platelet", "display_name": "Platelet", "score": 0.4487614929676056}, {"id": "https://openalex.org/keywords/reference-range", "display_name": "Reference range", "score": 0.42855238914489746}, {"id": "https://openalex.org/keywords/chromatography", "display_name": "Chromatography", "score": 0.3751027286052704}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.37293821573257446}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.3341570794582367}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.2619335651397705}], "concepts": [{"id": "https://openalex.org/C2780959883", "wikidata": "https://www.wikidata.org/wiki/Q111146", "display_name": "Hematocrit", "level": 2, "score": 0.8456312417984009}, {"id": "https://openalex.org/C2781058662", "wikidata": "https://www.wikidata.org/wiki/Q1358504", "display_name": "Mean corpuscular volume", "level": 3, "score": 0.6537782549858093}, {"id": "https://openalex.org/C2778917026", "wikidata": "https://www.wikidata.org/wiki/Q43041", "display_name": "Hemoglobin", "level": 2, "score": 0.6400008797645569}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.6073914170265198}, {"id": "https://openalex.org/C1621761", "wikidata": "https://www.wikidata.org/wiki/Q7997549", "display_name": "Whole blood", "level": 2, "score": 0.6027527451515198}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.5456727743148804}, {"id": "https://openalex.org/C184112429", "wikidata": "https://www.wikidata.org/wiki/Q476174", "display_name": "Serial dilution", "level": 3, "score": 0.49667173624038696}, {"id": "https://openalex.org/C10390740", "wikidata": "https://www.wikidata.org/wiki/Q2282401", "display_name": "Analyte", "level": 2, "score": 0.49512234330177307}, {"id": "https://openalex.org/C37557685", "wikidata": "https://www.wikidata.org/wiki/Q1896673", "display_name": "Blood volume", "level": 2, "score": 0.46333515644073486}, {"id": "https://openalex.org/C89560881", "wikidata": "https://www.wikidata.org/wiki/Q101026", "display_name": "Platelet", "level": 2, "score": 0.4487614929676056}, {"id": "https://openalex.org/C2778143274", "wikidata": "https://www.wikidata.org/wiki/Q1626599", "display_name": "Reference range", "level": 2, "score": 0.42855238914489746}, {"id": "https://openalex.org/C43617362", "wikidata": "https://www.wikidata.org/wiki/Q170050", "display_name": "Chromatography", "level": 1, "score": 0.3751027286052704}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.37293821573257446}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.3341570794582367}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.2619335651397705}, {"id": "https://openalex.org/C204787440", "wikidata": "https://www.wikidata.org/wiki/Q188504", "display_name": "Alternative medicine", "level": 2, "score": 0.0}], "mesh": [{"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D003936", "descriptor_name": "Diagnosis, Computer-Assisted", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D003936", "descriptor_name": "Diagnosis, Computer-Assisted", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D003936", "descriptor_name": "Diagnosis, Computer-Assisted", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007202", "descriptor_name": "Indicators and Reagents", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007202", "descriptor_name": "Indicators and Reagents", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007202", "descriptor_name": "Indicators and Reagents", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007753", "descriptor_name": "Laboratories", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D007753", "descriptor_name": "Laboratories", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D007753", "descriptor_name": "Laboratories", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013997", "descriptor_name": "Time Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013997", "descriptor_name": "Time Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013997", "descriptor_name": "Time Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "doi:10.1093/ajcp/111.3.387", "is_oa": false, "landing_page_url": "https://doi.org/10.1093/ajcp/111.3.387", "pdf_url": null, "source": {"id": "https://openalex.org/S15871148", "display_name": "American Journal of Clinical Pathology", "issn_l": "0002-9173", "issn": ["0002-9173", "1943-7722"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310311648", "host_organization_name": "Oxford University Press", "host_organization_lineage": ["https://openalex.org/P4310311648", "https://openalex.org/P4310311647"], "host_organization_lineage_names": ["Oxford University Press", "University of Oxford"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Clinical Pathology", "raw_type": "journal-article"}, {"id": "pmid:10078115", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/10078115", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American journal of clinical pathology", "raw_type": null}], "best_oa_location": null, "sustainable_development_goals": [{"display_name": "Life in Land", "id": "https://metadata.un.org/sdg/15", "score": 0.4699999988079071}], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 0, "referenced_works": [], "related_works": ["https://openalex.org/W2030920257", "https://openalex.org/W2075794279", "https://openalex.org/W2354083351", "https://openalex.org/W2351151515", "https://openalex.org/W2354660175", "https://openalex.org/W2374030108", "https://openalex.org/W2419075894", "https://openalex.org/W2363814837", "https://openalex.org/W2053263505", "https://openalex.org/W926190705"], "abstract_inverted_index": {"We": [0], "describe": [1], "a": [2, 17, 89, 163], "new,": [3], "easy-to-use": [4], "reagent,": [5], "Cyto-Chex": [6, 137], "(Streck": [7], "Laboratories,": [8], "Omaha,": [9], "Neb),": [10], "that": [11], "preserves": [12], "fresh": [13, 25], "whole": [14], "blood": [15, 26, 97, 115, 148, 184], "in": [16, 197], "non-cross-linking,": [18], "nonformalin": [19], "manner.": [20], "Target": [21], "values": [22], "assigned": [23], "to": [24, 36, 190], "were": [27, 52, 125], "essentially": [28], "met": [29], "after": [30, 94, 114], "preservation": [31, 95], "and": [32, 43, 57, 61, 65, 69, 75, 77, 80, 134, 144, 161], "storage": [33], "of": [34, 47, 83, 92, 96, 120, 141, 150, 166, 181, 193, 201], "up": [35], "31": [37], "days.": [38], "Respective": [39], "mean": [40, 71], "analytic": [41], "inaccuracies": [42], "short-term": [44], "intra-assay": [45], "coefficients": [46, 119], "variation": [48, 121], "(n": [49], "=": [50], "30)": [51], "as": [53], "follows:": [54], "WBCs,": [55], "6.7%": [56], "1.99%;": [58], "RBCs,": [59], "0.7%": [60], "0.76%;": [62], "hemoglobin,": [63, 130], "-1.8%": [64], "0.79%;": [66], "hematocrit,": [67, 132], "-0.3%": [68], "0.75%;": [70], "corpuscular": [72], "volume,": [73], "-1.0%": [74], "0.78%;": [76], "platelets,": [78], "6.9%": [79], "3.12%.": [81], "Linearity": [82], "dilution-sensitive": [84], "analytes": [85], "was": [86], "satisfactory": [87], "over": [88], "wide": [90, 164], "range": [91, 165], "dilutions": [93], "samples.": [98], "Ten": [99], "independent": [100], "laboratories": [101, 124], "using": [102], "10": [103], "different": [104], "instruments": [105], "determined": [106], "day-to-day": [107], "interassay": [108, 118], "imprecision": [109], "during": [110], "four": [111], "7-day": [112], "periods": [113], "preservation.": [116], "Mean": [117], "for": [122], "participating": [123], "WBC,": [126], "1.92%;": [127], "RBC,": [128], "1.00%;": [129], "1.29%;": [131], "2.00%;": [133], "platelets": [135], "3.29%.": [136], "enables": [138], "long-term": [139], "monitoring": [140], "instrument": [142], "accuracy": [143], "precision": [145], "with": [146, 157, 162, 176], "retained": [147], "specimens": [149], "healthy": [151], "persons.": [152], "Blood": [153], "from": [154], "patient": [155, 183], "cohorts": [156], "various": [158], "hematologic": [159], "disorders": [160], "numeric": [167], "abnormalities": [168], "and/or": [169], "parameter": [170], "aberrations": [171], "can": [172], "be": [173], "preserved": [174, 182], "satisfactorily": [175], "this": [177], "reagent.": [178], "The": [179], "reanalysis": [180], "samples": [185], "is": [186], "an": [187], "important": [188], "adjunct": [189], "the": [191], "use": [192], "commercial": [194], "control": [195, 199], "material": [196], "quality": [198], "programs": [200], "multichannel": [202], "hematology": [203], "analyzers.": [204]}, "counts_by_year": [{"year": 2023, "cited_by_count": 1}, {"year": 2019, "cited_by_count": 1}, {"year": 2012, "cited_by_count": 1}], "updated_date": "2026-01-13T01:12:25.745995", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W4206826889", "doi": "https://doi.org/10.1002/aisy.202170060", "title": "Artificial\u2010Intelligence\u2010Enabled Reagent\u2010Free Imaging Hematology Analyzer", "display_name": "Artificial\u2010Intelligence\u2010Enabled Reagent\u2010Free Imaging Hematology Analyzer", "relevance_score": 153.65192, "publication_year": 2021, "publication_date": "2021-08-01", "ids": {"openalex": "https://openalex.org/W4206826889", "doi": "https://doi.org/10.1002/aisy.202170060"}, "language": "en", "primary_location": {"id": "doi:10.1002/aisy.202170060", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/aisy.202170060", "pdf_url": null, "source": {"id": "https://openalex.org/S4210212817", "display_name": "Advanced Intelligent Systems", "issn_l": "2640-4567", "issn": ["2640-4567"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Advanced Intelligent Systems", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "doaj"], "open_access": {"is_oa": true, "oa_status": "gold", "oa_url": "https://doi.org/10.1002/aisy.202170060", "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5014493066", "display_name": "Xin Shu", "orcid": "https://orcid.org/0000-0001-9502-9807"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": false, "raw_author_name": "Xin Shu", "raw_affiliation_strings": ["Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": "https://orcid.org/0000-0001-9502-9807", "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5020418389", "display_name": "Sameera Sansare", "orcid": "https://orcid.org/0000-0002-4976-3282"}, "institutions": [{"id": "https://openalex.org/I140172145", "display_name": "University of Connecticut", "ror": "https://ror.org/02der9h97", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I140172145"]}, {"id": "https://openalex.org/I4210101648", "display_name": "Connecticut Children's Medical Center", "ror": "https://ror.org/01a1jjn24", "country_code": "US", "type": "funder", "lineage": ["https://openalex.org/I4210101648"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Sameera Sansare", "raw_affiliation_strings": ["Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "Department of Pharmaceutical Sciences University of Connecticut  Storrs CT 06269 USA", "Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, 06269 USA", "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "institution_ids": ["https://openalex.org/I4210101648"]}, {"raw_affiliation_string": "Department of Pharmaceutical Sciences University of Connecticut  Storrs CT 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5112574959", "display_name": "Di Jin", "orcid": "https://orcid.org/0009-0001-4646-5220"}, "institutions": [{"id": "https://openalex.org/I63966007", "display_name": "Massachusetts Institute of Technology", "ror": "https://ror.org/042nb2s44", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I63966007"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Di Jin", "raw_affiliation_strings": ["Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology  Cambridge MA 02139 USA", "Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139 USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology  Cambridge MA 02139 USA", "institution_ids": ["https://openalex.org/I63966007"]}, {"raw_affiliation_string": "Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139 USA", "institution_ids": ["https://openalex.org/I63966007"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5027286013", "display_name": "Xiangxiang Zeng", "orcid": "https://orcid.org/0000-0001-6201-0114"}, "institutions": [{"id": "https://openalex.org/I16609230", "display_name": "Hunan University", "ror": "https://ror.org/05htk5m33", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I16609230"]}], "countries": ["CN"], "is_corresponding": false, "raw_author_name": "Xiangxiang Zeng", "raw_affiliation_strings": ["School of Information Science and Engineering Hunan University  Changsha 410076 China", "School of Information Science and Engineering, Hunan University, Changsha, 410076 China"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "School of Information Science and Engineering Hunan University  Changsha 410076 China", "institution_ids": ["https://openalex.org/I16609230"]}, {"raw_affiliation_string": "School of Information Science and Engineering, Hunan University, Changsha, 410076 China", "institution_ids": ["https://openalex.org/I16609230"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5066840655", "display_name": "Raymond Kai\u2010Yu Tong", "orcid": "https://orcid.org/0000-0003-4375-653X"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": false, "raw_author_name": "Kai-Yu Tong", "raw_affiliation_strings": ["Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5018663240", "display_name": "Rishikesh Pandey", "orcid": "https://orcid.org/0000-0003-4975-3815"}, "institutions": [{"id": "https://openalex.org/I140172145", "display_name": "University of Connecticut", "ror": "https://ror.org/02der9h97", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I140172145"]}, {"id": "https://openalex.org/I4210101648", "display_name": "Connecticut Children's Medical Center", "ror": "https://ror.org/01a1jjn24", "country_code": "US", "type": "funder", "lineage": ["https://openalex.org/I4210101648"]}], "countries": ["US"], "is_corresponding": true, "raw_author_name": "Rishikesh Pandey", "raw_affiliation_strings": ["Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "Department of Biomedical Engineering University of Connecticut  Storrs CT 06269 USA", "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA", "Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269 USA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Connecticut Children's Innovation Center University of Connecticut School of Medicine  Farmington CT 06032 USA", "institution_ids": ["https://openalex.org/I4210101648"]}, {"raw_affiliation_string": "Department of Biomedical Engineering University of Connecticut  Storrs CT 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Connecticut Children's Innovation Center, University of Connecticut School of Medicine, Farmington, CT, 06032 USA", "institution_ids": ["https://openalex.org/I4210101648", "https://openalex.org/I140172145"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269 USA", "institution_ids": ["https://openalex.org/I140172145"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5022877503", "display_name": "Renjie Zhou", "orcid": "https://orcid.org/0000-0002-4761-6641"}, "institutions": [{"id": "https://openalex.org/I177725633", "display_name": "Chinese University of Hong Kong", "ror": "https://ror.org/00t33hh48", "country_code": "HK", "type": "education", "lineage": ["https://openalex.org/I177725633"]}], "countries": ["HK"], "is_corresponding": true, "raw_author_name": "Renjie Zhou", "raw_affiliation_strings": ["Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Shun Hing Institute of Advanced Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "Shun Hing Institute of Advanced Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China"], "raw_orcid": "https://orcid.org/0000-0002-4761-6641", "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Shun Hing Institute of Advanced Engineering The Chinese University of Hong Kong  Shatin New Territories Hong Kong China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}, {"raw_affiliation_string": "Shun Hing Institute of Advanced Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China", "institution_ids": ["https://openalex.org/I177725633"]}]}], "institutions": [], "countries_distinct_count": 3, "institutions_distinct_count": 7, "corresponding_author_ids": ["https://openalex.org/A5018663240", "https://openalex.org/A5022877503"], "corresponding_institution_ids": ["https://openalex.org/I140172145", "https://openalex.org/I177725633", "https://openalex.org/I4210101648"], "apc_list": {"value": 2750, "currency": "USD", "value_usd": 2750}, "apc_paid": {"value": 2750, "currency": "USD", "value_usd": 2750}, "fwci": 0.3884, "has_fulltext": false, "cited_by_count": 4, "citation_normalized_percentile": {"value": 0.62878702, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 94}, "biblio": {"volume": "3", "issue": "8", "first_page": null, "last_page": null}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.9473000168800354, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, "topics": [{"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.9473000168800354, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T11897", "display_name": "Digital Holography and Microscopy", "score": 0.9279999732971191, "subfield": {"id": "https://openalex.org/subfields/3107", "display_name": "Atomic and Molecular Physics, and Optics"}, "field": {"id": "https://openalex.org/fields/31", "display_name": "Physics and Astronomy"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.7429887056350708}, {"id": "https://openalex.org/keywords/artificial-intelligence", "display_name": "Artificial intelligence", "score": 0.5475451350212097}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.4963594079017639}, {"id": "https://openalex.org/keywords/spectrum-analyzer", "display_name": "Spectrum analyzer", "score": 0.4875182807445526}, {"id": "https://openalex.org/keywords/lens", "display_name": "Lens (geology)", "score": 0.48168835043907166}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.4803946614265442}, {"id": "https://openalex.org/keywords/phase", "display_name": "Phase (matter)", "score": 0.47562673687934875}, {"id": "https://openalex.org/keywords/medical-physics", "display_name": "Medical physics", "score": 0.4191851317882538}, {"id": "https://openalex.org/keywords/reagent", "display_name": "Reagent", "score": 0.4168759286403656}, {"id": "https://openalex.org/keywords/microscope", "display_name": "Microscope", "score": 0.4133506417274475}, {"id": "https://openalex.org/keywords/biomedical-engineering", "display_name": "Biomedical engineering", "score": 0.40737852454185486}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.37459495663642883}, {"id": "https://openalex.org/keywords/nuclear-medicine", "display_name": "Nuclear medicine", "score": 0.3499138057231903}, {"id": "https://openalex.org/keywords/computer-vision", "display_name": "Computer vision", "score": 0.3446711003780365}, {"id": "https://openalex.org/keywords/pattern-recognition", "display_name": "Pattern recognition (psychology)", "score": 0.33359333872795105}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.3161628246307373}, {"id": "https://openalex.org/keywords/optics", "display_name": "Optics", "score": 0.30811017751693726}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.29894065856933594}, {"id": "https://openalex.org/keywords/physics", "display_name": "Physics", "score": 0.17042276263237}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.15482786297798157}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.7429887056350708}, {"id": "https://openalex.org/C154945302", "wikidata": "https://www.wikidata.org/wiki/Q11660", "display_name": "Artificial intelligence", "level": 1, "score": 0.5475451350212097}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.4963594079017639}, {"id": "https://openalex.org/C158007255", "wikidata": "https://www.wikidata.org/wiki/Q1055222", "display_name": "Spectrum analyzer", "level": 2, "score": 0.4875182807445526}, {"id": "https://openalex.org/C15336307", "wikidata": "https://www.wikidata.org/wiki/Q1766051", "display_name": "Lens (geology)", "level": 2, "score": 0.48168835043907166}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.4803946614265442}, {"id": "https://openalex.org/C44280652", "wikidata": "https://www.wikidata.org/wiki/Q104837", "display_name": "Phase (matter)", "level": 2, "score": 0.47562673687934875}, {"id": "https://openalex.org/C19527891", "wikidata": "https://www.wikidata.org/wiki/Q1120908", "display_name": "Medical physics", "level": 1, "score": 0.4191851317882538}, {"id": "https://openalex.org/C40875361", "wikidata": "https://www.wikidata.org/wiki/Q2356542", "display_name": "Reagent", "level": 2, "score": 0.4168759286403656}, {"id": "https://openalex.org/C67649825", "wikidata": "https://www.wikidata.org/wiki/Q196538", "display_name": "Microscope", "level": 2, "score": 0.4133506417274475}, {"id": "https://openalex.org/C136229726", "wikidata": "https://www.wikidata.org/wiki/Q327092", "display_name": "Biomedical engineering", "level": 1, "score": 0.40737852454185486}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.37459495663642883}, {"id": "https://openalex.org/C2989005", "wikidata": "https://www.wikidata.org/wiki/Q214963", "display_name": "Nuclear medicine", "level": 1, "score": 0.3499138057231903}, {"id": "https://openalex.org/C31972630", "wikidata": "https://www.wikidata.org/wiki/Q844240", "display_name": "Computer vision", "level": 1, "score": 0.3446711003780365}, {"id": "https://openalex.org/C153180895", "wikidata": "https://www.wikidata.org/wiki/Q7148389", "display_name": "Pattern recognition (psychology)", "level": 2, "score": 0.33359333872795105}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.3161628246307373}, {"id": "https://openalex.org/C120665830", "wikidata": "https://www.wikidata.org/wiki/Q14620", "display_name": "Optics", "level": 1, "score": 0.30811017751693726}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.29894065856933594}, {"id": "https://openalex.org/C121332964", "wikidata": "https://www.wikidata.org/wiki/Q413", "display_name": "Physics", "level": 0, "score": 0.17042276263237}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.15482786297798157}, {"id": "https://openalex.org/C147789679", "wikidata": "https://www.wikidata.org/wiki/Q11372", "display_name": "Physical chemistry", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C76155785", "wikidata": "https://www.wikidata.org/wiki/Q418", "display_name": "Telecommunications", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C62520636", "wikidata": "https://www.wikidata.org/wiki/Q944", "display_name": "Quantum mechanics", "level": 1, "score": 0.0}], "mesh": [], "locations_count": 1, "locations": [{"id": "doi:10.1002/aisy.202170060", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/aisy.202170060", "pdf_url": null, "source": {"id": "https://openalex.org/S4210212817", "display_name": "Advanced Intelligent Systems", "issn_l": "2640-4567", "issn": ["2640-4567"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Advanced Intelligent Systems", "raw_type": "journal-article"}], "best_oa_location": {"id": "doi:10.1002/aisy.202170060", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/aisy.202170060", "pdf_url": null, "source": {"id": "https://openalex.org/S4210212817", "display_name": "Advanced Intelligent Systems", "issn_l": "2640-4567", "issn": ["2640-4567"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Advanced Intelligent Systems", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 0, "referenced_works": [], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W2367382573", "https://openalex.org/W3114788508", "https://openalex.org/W2364386882", "https://openalex.org/W2352314160", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W1601719760"], "abstract_inverted_index": {"Quantitative": [0], "Phase": [1], "Imaging": [2], "A": [3], "reagent-free": [4], "hematology": [5], "analyzer": [6], "is": [7, 69], "developed": [8], "in": [9, 27], "article": [10], "number": [11], "2000277": [12], "by": [13, 43, 51, 56, 64], "Rishikesh": [14], "Pandey,": [15], "Renjie": [16], "Zhou,": [17], "and": [18, 46], "co-workers.": [19], "The": [20], "researchers": [21], "employ": [22], "a": [23, 30, 44, 52], "quantitative": [24], "phase": [25, 47], "imaging": [26], "conjunction": [28], "with": [29], "neural": [31], "network": [32], "to": [33], "classify": [34], "leukocytes.": [35], "In": [36], "the": [37, 57, 65], "cover": [38], "image,": [39], "cells": [40], "are": [41, 49], "illuminated": [42], "laser": [45], "images": [48], "acquired": [50], "custom-built": [53], "microscope": [54], "(indicated": [55], "objective": [58], "lens).": [59], "An": [60], "AI": [61], "algorithm": [62], "(denoted": [63], "background": [66], "data": [67], "flow)": [68], "used": [70], "for": [71], "classifying": [72], "cells.": [73]}, "counts_by_year": [{"year": 2024, "cited_by_count": 1}, {"year": 2023, "cited_by_count": 1}, {"year": 2022, "cited_by_count": 1}, {"year": 2021, "cited_by_count": 1}], "updated_date": "2025-11-06T03:46:38.306776", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W1966742070", "doi": "https://doi.org/10.1111/ijlh.12130", "title": "Evaluation of the automated hematology analyzer <scp>ADVIA</scp><sup>\u00ae</sup> 120 for cerebrospinal fluid analysis and usage of unique hemolysis reagent", "display_name": "Evaluation of the automated hematology analyzer <scp>ADVIA</scp><sup>\u00ae</sup> 120 for cerebrospinal fluid analysis and usage of unique hemolysis reagent", "relevance_score": 123.67626, "publication_year": 2013, "publication_date": "2013-08-13", "ids": {"openalex": "https://openalex.org/W1966742070", "doi": "https://doi.org/10.1111/ijlh.12130", "mag": "1966742070", "pmid": "https://pubmed.ncbi.nlm.nih.gov/23937551"}, "language": "en", "primary_location": {"id": "doi:10.1111/ijlh.12130", "is_oa": false, "landing_page_url": "https://doi.org/10.1111/ijlh.12130", "pdf_url": null, "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5085059847", "display_name": "Hiroko Tanada", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210124582", "display_name": "Osaka Hospital", "ror": "https://ror.org/02wcsw791", "country_code": "JP", "type": "healthcare", "lineage": ["https://openalex.org/I4210124582", "https://openalex.org/I4210132540"]}, {"id": "https://openalex.org/I205143321", "display_name": "Osaka Medical and Pharmaceutical University", "ror": "https://ror.org/01y2kdt21", "country_code": "JP", "type": "education", "lineage": ["https://openalex.org/I205143321"]}], "countries": ["JP"], "is_corresponding": false, "raw_author_name": "H. Tanada", "raw_affiliation_strings": ["Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "institution_ids": ["https://openalex.org/I205143321", "https://openalex.org/I4210124582"]}, {"raw_affiliation_string": "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan", "institution_ids": ["https://openalex.org/I205143321"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5114183874", "display_name": "Toshiyuki Ikemoto", "orcid": null}, "institutions": [{"id": "https://openalex.org/I205143321", "display_name": "Osaka Medical and Pharmaceutical University", "ror": "https://ror.org/01y2kdt21", "country_code": "JP", "type": "education", "lineage": ["https://openalex.org/I205143321"]}, {"id": "https://openalex.org/I4210124582", "display_name": "Osaka Hospital", "ror": "https://ror.org/02wcsw791", "country_code": "JP", "type": "healthcare", "lineage": ["https://openalex.org/I4210124582", "https://openalex.org/I4210132540"]}], "countries": ["JP"], "is_corresponding": false, "raw_author_name": "T. Ikemoto", "raw_affiliation_strings": ["Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "institution_ids": ["https://openalex.org/I205143321", "https://openalex.org/I4210124582"]}, {"raw_affiliation_string": "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan", "institution_ids": ["https://openalex.org/I205143321"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5031290631", "display_name": "Ryota Masutani", "orcid": "https://orcid.org/0000-0002-0378-7617"}, "institutions": [{"id": "https://openalex.org/I205143321", "display_name": "Osaka Medical and Pharmaceutical University", "ror": "https://ror.org/01y2kdt21", "country_code": "JP", "type": "education", "lineage": ["https://openalex.org/I205143321"]}, {"id": "https://openalex.org/I4210124582", "display_name": "Osaka Hospital", "ror": "https://ror.org/02wcsw791", "country_code": "JP", "type": "healthcare", "lineage": ["https://openalex.org/I4210124582", "https://openalex.org/I4210132540"]}], "countries": ["JP"], "is_corresponding": false, "raw_author_name": "R. Masutani", "raw_affiliation_strings": ["Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "institution_ids": ["https://openalex.org/I205143321", "https://openalex.org/I4210124582"]}, {"raw_affiliation_string": "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan", "institution_ids": ["https://openalex.org/I205143321"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5058940083", "display_name": "Hidetaka Tanaka", "orcid": null}, "institutions": [{"id": "https://openalex.org/I205143321", "display_name": "Osaka Medical and Pharmaceutical University", "ror": "https://ror.org/01y2kdt21", "country_code": "JP", "type": "education", "lineage": ["https://openalex.org/I205143321"]}, {"id": "https://openalex.org/I4210124582", "display_name": "Osaka Hospital", "ror": "https://ror.org/02wcsw791", "country_code": "JP", "type": "healthcare", "lineage": ["https://openalex.org/I4210124582", "https://openalex.org/I4210132540"]}], "countries": ["JP"], "is_corresponding": false, "raw_author_name": "H. Tanaka", "raw_affiliation_strings": ["Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan", "institution_ids": ["https://openalex.org/I205143321", "https://openalex.org/I4210124582"]}, {"raw_affiliation_string": "Central Clinical Laboratory, Osaka Medical College Hospital, Osaka, Japan", "institution_ids": ["https://openalex.org/I205143321"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5110421415", "display_name": "T Takubo", "orcid": null}, "institutions": [{"id": "https://openalex.org/I205143321", "display_name": "Osaka Medical and Pharmaceutical University", "ror": "https://ror.org/01y2kdt21", "country_code": "JP", "type": "education", "lineage": ["https://openalex.org/I205143321"]}], "countries": ["JP"], "is_corresponding": true, "raw_author_name": "T. Takubo", "raw_affiliation_strings": ["Department of Clinical and Laboratory Medicine Osaka Medical College Osaka Japan", "Department of Clinical and Laboratory Medicine, Osaka Medical College, Osaka, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Clinical and Laboratory Medicine Osaka Medical College Osaka Japan", "institution_ids": ["https://openalex.org/I205143321"]}, {"raw_affiliation_string": "Department of Clinical and Laboratory Medicine, Osaka Medical College, Osaka, Japan", "institution_ids": ["https://openalex.org/I205143321"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 5, "corresponding_author_ids": ["https://openalex.org/A5110421415"], "corresponding_institution_ids": ["https://openalex.org/I205143321"], "apc_list": {"value": 3550, "currency": "USD", "value_usd": 3550}, "apc_paid": null, "fwci": 0.1761, "has_fulltext": false, "cited_by_count": 10, "citation_normalized_percentile": {"value": 0.5611402, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 96}, "biblio": {"volume": "36", "issue": "1", "first_page": "83", "last_page": "91"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9018999934196472, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9018999934196472, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.02419999986886978, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T11393", "display_name": "Biosensors and Analytical Detection", "score": 0.006599999964237213, "subfield": {"id": "https://openalex.org/subfields/2204", "display_name": "Biomedical Engineering"}, "field": {"id": "https://openalex.org/fields/22", "display_name": "Engineering"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.9302297830581665}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.8126715421676636}, {"id": "https://openalex.org/keywords/hemolysis", "display_name": "Hemolysis", "score": 0.7910510301589966}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.6549444794654846}, {"id": "https://openalex.org/keywords/white-blood-cell", "display_name": "White blood cell", "score": 0.6069316864013672}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.5507036447525024}, {"id": "https://openalex.org/keywords/leukocyte-counts", "display_name": "Leukocyte Counts", "score": 0.5100727677345276}, {"id": "https://openalex.org/keywords/blood-cell", "display_name": "Blood cell", "score": 0.46718719601631165}, {"id": "https://openalex.org/keywords/cerebrospinal-fluid", "display_name": "Cerebrospinal fluid", "score": 0.4519205093383789}, {"id": "https://openalex.org/keywords/immunology", "display_name": "Immunology", "score": 0.41084975004196167}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.3558918237686157}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.9302297830581665}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.8126715421676636}, {"id": "https://openalex.org/C2779902561", "wikidata": "https://www.wikidata.org/wiki/Q471706", "display_name": "Hemolysis", "level": 2, "score": 0.7910510301589966}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.6549444794654846}, {"id": "https://openalex.org/C2778488018", "wikidata": "https://www.wikidata.org/wiki/Q42395", "display_name": "White blood cell", "level": 2, "score": 0.6069316864013672}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.5507036447525024}, {"id": "https://openalex.org/C2909092058", "wikidata": "https://www.wikidata.org/wiki/Q42395", "display_name": "Leukocyte Counts", "level": 2, "score": 0.5100727677345276}, {"id": "https://openalex.org/C2779979121", "wikidata": "https://www.wikidata.org/wiki/Q211709", "display_name": "Blood cell", "level": 2, "score": 0.46718719601631165}, {"id": "https://openalex.org/C2779651940", "wikidata": "https://www.wikidata.org/wiki/Q54196", "display_name": "Cerebrospinal fluid", "level": 2, "score": 0.4519205093383789}, {"id": "https://openalex.org/C203014093", "wikidata": "https://www.wikidata.org/wiki/Q101929", "display_name": "Immunology", "level": 1, "score": 0.41084975004196167}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.3558918237686157}], "mesh": [{"descriptor_ui": "D002555", "descriptor_name": "Cerebrospinal Fluid", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D002555", "descriptor_name": "Cerebrospinal Fluid", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D002555", "descriptor_name": "Cerebrospinal Fluid", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D002555", "descriptor_name": "Cerebrospinal Fluid", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D002555", "descriptor_name": "Cerebrospinal Fluid", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D002555", "descriptor_name": "Cerebrospinal Fluid", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D004906", "descriptor_name": "Erythrocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D004906", "descriptor_name": "Erythrocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D004906", "descriptor_name": "Erythrocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D006461", "descriptor_name": "Hemolysis", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006461", "descriptor_name": "Hemolysis", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006461", "descriptor_name": "Hemolysis", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007753", "descriptor_name": "Laboratories", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007753", "descriptor_name": "Laboratories", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007753", "descriptor_name": "Laboratories", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D007962", "descriptor_name": "Leukocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D007962", "descriptor_name": "Leukocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D007962", "descriptor_name": "Leukocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D057205", "descriptor_name": "Automation, Laboratory", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D057205", "descriptor_name": "Automation, Laboratory", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D057205", "descriptor_name": "Automation, Laboratory", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D057205", "descriptor_name": "Automation, Laboratory", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D057205", "descriptor_name": "Automation, Laboratory", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D057205", "descriptor_name": "Automation, Laboratory", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "doi:10.1111/ijlh.12130", "is_oa": false, "landing_page_url": "https://doi.org/10.1111/ijlh.12130", "pdf_url": null, "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, {"id": "pmid:23937551", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/23937551", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International journal of laboratory hematology", "raw_type": null}], "best_oa_location": null, "sustainable_development_goals": [{"display_name": "Good health and well-being", "id": "https://metadata.un.org/sdg/3", "score": 0.49000000953674316}], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 8, "referenced_works": ["https://openalex.org/W1978404601", "https://openalex.org/W2004804759", "https://openalex.org/W2108010664", "https://openalex.org/W2168424095", "https://openalex.org/W2418895521", "https://openalex.org/W2904626836", "https://openalex.org/W3172360775", "https://openalex.org/W6685064970"], "related_works": ["https://openalex.org/W1970439953", "https://openalex.org/W2354377647", "https://openalex.org/W3035573075", "https://openalex.org/W2751692968", "https://openalex.org/W1851003042", "https://openalex.org/W4226393424", "https://openalex.org/W2335099826", "https://openalex.org/W1835966817", "https://openalex.org/W1577078997", "https://openalex.org/W2415013881"], "abstract_inverted_index": {"INTRODUCTION:": [0], "In": [1], "this": [2], "study,": [3], "we": [4], "evaluated": [5], "the": [6, 9, 30, 65, 72, 94, 119, 127, 136, 160, 167, 196], "performance": [7], "of": [8, 51, 67, 114, 187], "ADVIA": [10, 31, 73, 161, 197], "120": [11, 32, 74, 162, 198], "hematology": [12, 33, 75, 121, 163, 199], "system": [13, 76, 164], "for": [14, 42, 184], "cerebrospinal": [15], "fluid": [16], "(CSF)": [17], "assay.": [18], "METHODS:": [19], "Cell": [20], "counts": [21, 57, 63, 70, 142, 192], "and": [22, 58, 93, 143, 170, 193], "leukocyte": [23, 112, 144, 171], "differentials": [24, 194], "in": [25, 147, 173], "CSF": [26, 44, 68, 115, 188], "were": [27, 77], "examined": [28], "with": [29, 126, 140], "system,": [34, 122], "while": [35], "simultaneously": [36], "confirming": [37], "an": [38], "effective": [39], "hemolysis": [40, 132, 177, 185], "agent": [41], "automated": [43], "cell": [45, 55, 61, 69, 141, 191], "counts.": [46], "RESULTS:": [47], "The": [48, 84, 105, 111, 130, 175], "detection": [49], "limits": [50], "both": [52], "white": [53], "blood": [54, 60], "(WBC)": [56], "red": [59], "(RBC)": [62], "on": [64], "measurement": [66], "by": [71, 118, 195], "superior": [78], "at": [79], "2": [80], "cells/\u03bcL": [81], "(10(-6)": [82], "L).": [83], "WBC": [85, 168], "count": [86, 96, 169], "was": [87, 97], "linear": [88, 98], "up": [89, 99], "to": [90, 100, 181], "9.850": [91], "cells/\u03bcL,": [92], "RBC": [95], "approximately": [101, 152], "20": [102], "000": [103], "cells/\u03bcL.": [104], "intrarun": [106], "reproducibility": [107], "indicated": [108], "good": [109, 124], "precision.": [110], "differential": [113, 172], "cells,": [116], "performed": [117], "ADVIA120": [120], "showed": [123], "correlation": [125], "microscopic": [128], "procedure.": [129], "VersaLyse": [131, 176], "solution": [133, 178], "efficiently": [134], "lysed": [135], "samples": [137], "without": [138], "interfering": [139], "differential,": [145], "even": [146], "a": [148], "sample": [149], "that": [150], "included": [151], "50": [153], "000/\u03bcL": [154], "RBC.": [155], "CONCLUSION:": [156], "These": [157], "data": [158], "show": [159], "correctly": [165], "measured": [166], "CSF.": [174], "is": [179], "considered": [180], "be": [182], "optimal": [183], "treatment": [186], "when": [189], "measuring": [190], "system.": [200]}, "counts_by_year": [{"year": 2024, "cited_by_count": 1}, {"year": 2022, "cited_by_count": 2}, {"year": 2021, "cited_by_count": 1}, {"year": 2020, "cited_by_count": 1}, {"year": 2019, "cited_by_count": 1}, {"year": 2018, "cited_by_count": 1}, {"year": 2017, "cited_by_count": 2}, {"year": 2015, "cited_by_count": 1}], "updated_date": "2026-04-29T09:16:38.111599", "created_date": "2016-06-24T00:00:00"}, {"id": "https://openalex.org/W4292872731", "doi": "https://doi.org/10.48550/arxiv.2012.08518", "title": "Artificial Intelligence Enabled Reagent-free Imaging Hematology Analyzer", "display_name": "Artificial Intelligence Enabled Reagent-free Imaging Hematology Analyzer", "relevance_score": 103.81976, "publication_year": 2020, "publication_date": "2020-12-15", "ids": {"openalex": "https://openalex.org/W4292872731", "doi": "https://doi.org/10.48550/arxiv.2012.08518"}, "language": "en", "primary_location": {"id": "pmh:oai:arXiv.org:2012.08518", "is_oa": true, "landing_page_url": "http://arxiv.org/abs/2012.08518", "pdf_url": "https://arxiv.org/pdf/2012.08518", "source": {"id": "https://openalex.org/S4306400194", "display_name": "arXiv (Cornell University)", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I205783295", "host_organization_name": "Cornell University", "host_organization_lineage": ["https://openalex.org/I205783295"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "", "raw_type": "text"}, "type": "preprint", "indexed_in": ["arxiv", "datacite"], "open_access": {"is_oa": true, "oa_status": "green", "oa_url": "https://arxiv.org/pdf/2012.08518", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5100688409", "display_name": "Xin Shu", "orcid": "https://orcid.org/0009-0000-8337-331X"}, "institutions": [], "countries": [], "is_corresponding": true, "raw_author_name": "Shu, Xin", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5080972381", "display_name": "Sameera Sansre", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Sansre, Sameera", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5012455357", "display_name": "Di Jin", "orcid": "https://orcid.org/0000-0002-7445-9936"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Jin, Di", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5027286013", "display_name": "Xiangxiang Zeng", "orcid": "https://orcid.org/0000-0001-6201-0114"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Zeng, Xiangxiang", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5066840655", "display_name": "Raymond Kai\u2010Yu Tong", "orcid": "https://orcid.org/0000-0003-4375-653X"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Tong, Kai-Yu", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5018663240", "display_name": "Rishikesh Pandey", "orcid": "https://orcid.org/0000-0003-4975-3815"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Pandey, Rishikesh", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "last", "author": {"id": "https://openalex.org/A5022877503", "display_name": "Renjie Zhou", "orcid": "https://orcid.org/0000-0002-4761-6641"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Zhou, Renjie", "raw_affiliation_strings": [], "affiliations": []}], "institutions": [], "countries_distinct_count": 0, "institutions_distinct_count": 7, "corresponding_author_ids": ["https://openalex.org/A5100688409"], "corresponding_institution_ids": [], "apc_list": null, "apc_paid": null, "fwci": null, "has_fulltext": false, "cited_by_count": 1, "citation_normalized_percentile": null, "cited_by_percentile_year": null, "biblio": {"volume": null, "issue": null, "first_page": null, "last_page": null}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.9988999962806702, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, "topics": [{"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.9988999962806702, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T12167", "display_name": "Bacterial Identification and Susceptibility Testing", "score": 0.98580002784729, "subfield": {"id": "https://openalex.org/subfields/1308", "display_name": "Clinical Biochemistry"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.9843999743461609, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.765272319316864}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.6742494702339172}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.49191904067993164}, {"id": "https://openalex.org/keywords/blood-smear", "display_name": "Blood smear", "score": 0.4594164490699768}, {"id": "https://openalex.org/keywords/artificial-intelligence", "display_name": "Artificial intelligence", "score": 0.4498084783554077}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.38296300172805786}, {"id": "https://openalex.org/keywords/biomedical-engineering", "display_name": "Biomedical engineering", "score": 0.3781886100769043}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.3212025463581085}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.31250953674316406}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.765272319316864}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.6742494702339172}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.49191904067993164}, {"id": "https://openalex.org/C3017819844", "wikidata": "https://www.wikidata.org/wiki/Q886475", "display_name": "Blood smear", "level": 3, "score": 0.4594164490699768}, {"id": "https://openalex.org/C154945302", "wikidata": "https://www.wikidata.org/wiki/Q11660", "display_name": "Artificial intelligence", "level": 1, "score": 0.4498084783554077}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.38296300172805786}, {"id": "https://openalex.org/C136229726", "wikidata": "https://www.wikidata.org/wiki/Q327092", "display_name": "Biomedical engineering", "level": 1, "score": 0.3781886100769043}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.3212025463581085}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.31250953674316406}, {"id": "https://openalex.org/C2778048844", "wikidata": "https://www.wikidata.org/wiki/Q12156", "display_name": "Malaria", "level": 2, "score": 0.0}], "mesh": [], "locations_count": 2, "locations": [{"id": "pmh:oai:arXiv.org:2012.08518", "is_oa": true, "landing_page_url": "http://arxiv.org/abs/2012.08518", "pdf_url": "https://arxiv.org/pdf/2012.08518", "source": {"id": "https://openalex.org/S4306400194", "display_name": "arXiv (Cornell University)", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I205783295", "host_organization_name": "Cornell University", "host_organization_lineage": ["https://openalex.org/I205783295"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "", "raw_type": "text"}, {"id": "doi:10.48550/arxiv.2012.08518", "is_oa": true, "landing_page_url": "https://doi.org/10.48550/arxiv.2012.08518", "pdf_url": null, "source": {"id": "https://openalex.org/S4306400194", "display_name": "arXiv (Cornell University)", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I205783295", "host_organization_name": "Cornell University", "host_organization_lineage": ["https://openalex.org/I205783295"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": null, "is_accepted": false, "is_published": null, "raw_source_name": null, "raw_type": "article"}], "best_oa_location": {"id": "pmh:oai:arXiv.org:2012.08518", "is_oa": true, "landing_page_url": "http://arxiv.org/abs/2012.08518", "pdf_url": "https://arxiv.org/pdf/2012.08518", "source": {"id": "https://openalex.org/S4306400194", "display_name": "arXiv (Cornell University)", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I205783295", "host_organization_name": "Cornell University", "host_organization_lineage": ["https://openalex.org/I205783295"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "", "raw_type": "text"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 0, "referenced_works": [], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W3114788508", "https://openalex.org/W2352314160", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W1601719760", "https://openalex.org/W2359341290", "https://openalex.org/W2351951261"], "abstract_inverted_index": {"Leukocyte": [0], "differential": [1], "test": [2, 80], "is": [3, 49, 139], "a": [4, 20, 53, 66, 112], "widely": [5], "performed": [6], "clinical": [7], "procedure": [8], "for": [9, 154], "screening": [10, 157], "infectious": [11, 159], "diseases.": [12, 160], "Existing": [13], "hematology": [14, 33], "analyzers": [15], "require": [16], "labor-intensive": [17], "work": [18], "and": [19, 82, 99, 118, 128, 142], "panel": [21], "of": [22, 42, 61, 75, 107, 132, 158], "expensive": [23], "reagents.": [24], "Here": [25], "we": [26, 136], "report": [27], "an": [28], "artificial-intelligence": [29], "enabled": [30], "reagent-free": [31], "imaging": [32], "analyzer": [34], "(AIRFIHA)": [35], "modality": [36], "that": [37], "can": [38, 143], "accurately": [39], "classify": [40], "subpopulations": [41], "leukocytes": [43, 63], "with": [44], "minimal": [45], "sample": [46], "preparation.": [47], "AIRFIHA": [48, 76, 89, 138], "realized": [50], "through": [51], "training": [52], "two-step": [54], "residual": [55], "neural": [56], "network": [57], "using": [58], "label-free": [59], "images": [60], "separated": [62], "acquired": [64], "from": [65], "custom-built": [67], "quantitative": [68], "phase": [69], "microscope.": [70], "We": [71], "validated": [72], "the": [73, 104, 155], "performance": [74], "in": [77, 93, 97, 115, 147], "randomly": [78], "selected": [79], "set": [81], "cross-validated": [83], "it": [84], "across": [85], "all": [86], "blood": [87], "donors.": [88], "outperforms": [90], "current": [91], "methods": [92], "classification": [94], "accuracy,": [95], "especially": [96], "B": [98], "T": [100], "lymphocytes,": [101], "while": [102], "preserving": [103], "natural": [105], "state": [106], "cells.": [108, 120], "It": [109], "also": [110, 144], "shows": [111], "promising": [113], "potential": [114], "differentiating": [116], "CD4": [117], "CD8": [119], "Owing": [121], "to": [122], "its": [123], "easy": [124], "operation,": [125], "low": [126], "cost,": [127], "strong": [129], "discerning": [130], "capability": [131], "complex": [133], "leukocyte": [134], "subpopulations,": [135], "envision": [137], "clinically": [140], "translatable": [141], "be": [145], "deployed": [146], "resource-limited": [148], "settings,": [149], "e.g.,": [150], "during": [151], "pandemic": [152], "situations": [153], "rapid": [156]}, "counts_by_year": [{"year": 2022, "cited_by_count": 1}], "updated_date": "2026-02-09T09:26:11.010843", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W2069198171", "doi": "https://doi.org/10.1002/cyto.10068", "title": "CD45\u2010assisted Pan<i>Leuco</i>gating for accurate, cost\u2010effective dual\u2010platform CD4+ T\u2010cell enumeration", "display_name": "CD45\u2010assisted Pan<i>Leuco</i>gating for accurate, cost\u2010effective dual\u2010platform CD4+ T\u2010cell enumeration", "relevance_score": 95.66779, "publication_year": 2002, "publication_date": "2002-04-15", "ids": {"openalex": "https://openalex.org/W2069198171", "doi": "https://doi.org/10.1002/cyto.10068", "mag": "2069198171", "pmid": "https://pubmed.ncbi.nlm.nih.gov/12116348"}, "language": "en", "primary_location": {"id": "doi:10.1002/cyto.10068", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/cyto.10068", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cyto.10068", "source": {"id": "https://openalex.org/S75647499", "display_name": "Cytometry", "issn_l": "0196-4763", "issn": ["0196-4763", "1097-0320"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Cytometry", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "hybrid", "oa_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cyto.10068", "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5043116870", "display_name": "Deborah K. Glencross", "orcid": "https://orcid.org/0000-0001-7106-769X"}, "institutions": [{"id": "https://openalex.org/I192619145", "display_name": "University of the Witwatersrand", "ror": "https://ror.org/03rp50x72", "country_code": "ZA", "type": "education", "lineage": ["https://openalex.org/I192619145"]}], "countries": ["ZA"], "is_corresponding": true, "raw_author_name": "Deborah Glencross", "raw_affiliation_strings": ["Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, PO Box 2551 Houghton, 2041, South Africa. glencross@mighty.co.za", "*Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, PO Box 2551 Houghton, 2041, South Africa. glencross@mighty.co.za", "institution_ids": ["https://openalex.org/I192619145"]}, {"raw_affiliation_string": "*Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa", "institution_ids": ["https://openalex.org/I192619145"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5027166506", "display_name": "Lesley Scott", "orcid": "https://orcid.org/0000-0001-6573-9525"}, "institutions": [{"id": "https://openalex.org/I192619145", "display_name": "University of the Witwatersrand", "ror": "https://ror.org/03rp50x72", "country_code": "ZA", "type": "education", "lineage": ["https://openalex.org/I192619145"]}], "countries": ["ZA"], "is_corresponding": false, "raw_author_name": "Lesley E. Scott", "raw_affiliation_strings": ["Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa", "*Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa", "institution_ids": ["https://openalex.org/I192619145"]}, {"raw_affiliation_string": "*Department of Molecular Medicine and Hematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa", "institution_ids": ["https://openalex.org/I192619145"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5034520073", "display_name": "Ilesh Jani", "orcid": "https://orcid.org/0000-0002-6880-6655"}, "institutions": [{"id": "https://openalex.org/I2801138448", "display_name": "The Royal Free Hospital", "ror": "https://ror.org/01ge67z96", "country_code": "GB", "type": "healthcare", "lineage": ["https://openalex.org/I169248724", "https://openalex.org/I2801138448"]}, {"id": "https://openalex.org/I45129253", "display_name": "University College London", "ror": "https://ror.org/02jx3x895", "country_code": "GB", "type": "education", "lineage": ["https://openalex.org/I124357947", "https://openalex.org/I45129253"]}], "countries": ["GB"], "is_corresponding": false, "raw_author_name": "Ilesh V. Jani", "raw_affiliation_strings": ["HIV Immunology, Department of Immunology and Molecular Pathology, Royal Free and University College Medical School, London, United Kingdom"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "HIV Immunology, Department of Immunology and Molecular Pathology, Royal Free and University College Medical School, London, United Kingdom", "institution_ids": ["https://openalex.org/I2801138448", "https://openalex.org/I45129253"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5080669957", "display_name": "David Barnett", "orcid": "https://orcid.org/0000-0002-7658-5856"}, "institutions": [{"id": "https://openalex.org/I2801732343", "display_name": "Royal Hallamshire Hospital", "ror": "https://ror.org/00514rc81", "country_code": "GB", "type": "healthcare", "lineage": ["https://openalex.org/I2801732343", "https://openalex.org/I4210102902"]}], "countries": ["GB"], "is_corresponding": false, "raw_author_name": "David Barnett", "raw_affiliation_strings": ["U.K. NEQAS for Leucocyte Immunophenotyping, Royal Hallamshire Hospital, Sheffield, United Kingdom"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "U.K. NEQAS for Leucocyte Immunophenotyping, Royal Hallamshire Hospital, Sheffield, United Kingdom", "institution_ids": ["https://openalex.org/I2801732343"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5045532145", "display_name": "George Janossy", "orcid": null}, "institutions": [{"id": "https://openalex.org/I45129253", "display_name": "University College London", "ror": "https://ror.org/02jx3x895", "country_code": "GB", "type": "education", "lineage": ["https://openalex.org/I124357947", "https://openalex.org/I45129253"]}, {"id": "https://openalex.org/I2801138448", "display_name": "The Royal Free Hospital", "ror": "https://ror.org/01ge67z96", "country_code": "GB", "type": "healthcare", "lineage": ["https://openalex.org/I169248724", "https://openalex.org/I2801138448"]}], "countries": ["GB"], "is_corresponding": false, "raw_author_name": "George Janossy", "raw_affiliation_strings": ["HIV Immunology, Department of Immunology and Molecular Pathology, Royal Free and University College Medical School, London, United Kingdom"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "HIV Immunology, Department of Immunology and Molecular Pathology, Royal Free and University College Medical School, London, United Kingdom", "institution_ids": ["https://openalex.org/I2801138448", "https://openalex.org/I45129253"]}]}], "institutions": [], "countries_distinct_count": 2, "institutions_distinct_count": 5, "corresponding_author_ids": ["https://openalex.org/A5043116870"], "corresponding_institution_ids": ["https://openalex.org/I192619145"], "apc_list": null, "apc_paid": null, "fwci": 3.2208, "has_fulltext": true, "cited_by_count": 158, "citation_normalized_percentile": {"value": 0.92452549, "is_in_top_1_percent": false, "is_in_top_10_percent": true}, "cited_by_percentile_year": {"min": 91, "max": 99}, "biblio": {"volume": "50", "issue": "2", "first_page": "69", "last_page": "77"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11289", "display_name": "Single-cell and spatial transcriptomics", "score": 0.7560999989509583, "subfield": {"id": "https://openalex.org/subfields/1312", "display_name": "Molecular Biology"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, "topics": [{"id": "https://openalex.org/T11289", "display_name": "Single-cell and spatial transcriptomics", "score": 0.7560999989509583, "subfield": {"id": "https://openalex.org/subfields/1312", "display_name": "Molecular Biology"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.02930000051856041, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T12859", "display_name": "Cell Image Analysis Techniques", "score": 0.026000000536441803, "subfield": {"id": "https://openalex.org/subfields/1304", "display_name": "Biophysics"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/gating", "display_name": "Gating", "score": 0.7649495601654053}, {"id": "https://openalex.org/keywords/enumeration", "display_name": "Enumeration", "score": 0.6255229711532593}, {"id": "https://openalex.org/keywords/flow-cytometry", "display_name": "Flow cytometry", "score": 0.6242302060127258}, {"id": "https://openalex.org/keywords/cytometry", "display_name": "Cytometry", "score": 0.5475854873657227}, {"id": "https://openalex.org/keywords/nuclear-medicine", "display_name": "Nuclear medicine", "score": 0.5005495548248291}, {"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.49961376190185547}, {"id": "https://openalex.org/keywords/accuracy-and-precision", "display_name": "Accuracy and precision", "score": 0.45214658975601196}, {"id": "https://openalex.org/keywords/lymphocyte", "display_name": "Lymphocyte", "score": 0.4282894730567932}, {"id": "https://openalex.org/keywords/peripheral-blood", "display_name": "Peripheral blood", "score": 0.42626842856407166}, {"id": "https://openalex.org/keywords/diagnostic-accuracy", "display_name": "Diagnostic accuracy", "score": 0.41871920228004456}, {"id": "https://openalex.org/keywords/analytical-chemistry", "display_name": "Analytical Chemistry (journal)", "score": 0.3965705931186676}, {"id": "https://openalex.org/keywords/mathematics", "display_name": "Mathematics", "score": 0.3846967816352844}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.35614439845085144}, {"id": "https://openalex.org/keywords/molecular-biology", "display_name": "Molecular biology", "score": 0.34718406200408936}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.3296070694923401}, {"id": "https://openalex.org/keywords/biomedical-engineering", "display_name": "Biomedical engineering", "score": 0.3255264163017273}, {"id": "https://openalex.org/keywords/statistics", "display_name": "Statistics", "score": 0.2974625825881958}, {"id": "https://openalex.org/keywords/chromatography", "display_name": "Chromatography", "score": 0.25805988907814026}, {"id": "https://openalex.org/keywords/immunology", "display_name": "Immunology", "score": 0.2525579333305359}, {"id": "https://openalex.org/keywords/biology", "display_name": "Biology", "score": 0.2474631667137146}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.22364965081214905}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.18421408534049988}, {"id": "https://openalex.org/keywords/biophysics", "display_name": "Biophysics", "score": 0.09393656253814697}, {"id": "https://openalex.org/keywords/combinatorics", "display_name": "Combinatorics", "score": 0.09338480234146118}], "concepts": [{"id": "https://openalex.org/C194544171", "wikidata": "https://www.wikidata.org/wiki/Q21105679", "display_name": "Gating", "level": 2, "score": 0.7649495601654053}, {"id": "https://openalex.org/C156340839", "wikidata": "https://www.wikidata.org/wiki/Q2704791", "display_name": "Enumeration", "level": 2, "score": 0.6255229711532593}, {"id": "https://openalex.org/C553184892", "wikidata": "https://www.wikidata.org/wiki/Q1141429", "display_name": "Flow cytometry", "level": 2, "score": 0.6242302060127258}, {"id": "https://openalex.org/C2780339063", "wikidata": "https://www.wikidata.org/wiki/Q5201367", "display_name": "Cytometry", "level": 3, "score": 0.5475854873657227}, {"id": "https://openalex.org/C2989005", "wikidata": "https://www.wikidata.org/wiki/Q214963", "display_name": "Nuclear medicine", "level": 1, "score": 0.5005495548248291}, {"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.49961376190185547}, {"id": "https://openalex.org/C202799725", "wikidata": "https://www.wikidata.org/wiki/Q272035", "display_name": "Accuracy and precision", "level": 2, "score": 0.45214658975601196}, {"id": "https://openalex.org/C2777761686", "wikidata": "https://www.wikidata.org/wiki/Q715347", "display_name": "Lymphocyte", "level": 2, "score": 0.4282894730567932}, {"id": "https://openalex.org/C3017910909", "wikidata": "https://www.wikidata.org/wiki/Q618363", "display_name": "Peripheral blood", "level": 2, "score": 0.42626842856407166}, {"id": "https://openalex.org/C3020132585", "wikidata": "https://www.wikidata.org/wiki/Q2671652", "display_name": "Diagnostic accuracy", "level": 2, "score": 0.41871920228004456}, {"id": "https://openalex.org/C113196181", "wikidata": "https://www.wikidata.org/wiki/Q485223", "display_name": "Analytical Chemistry (journal)", "level": 2, "score": 0.3965705931186676}, {"id": "https://openalex.org/C33923547", "wikidata": "https://www.wikidata.org/wiki/Q395", "display_name": "Mathematics", "level": 0, "score": 0.3846967816352844}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.35614439845085144}, {"id": "https://openalex.org/C153911025", "wikidata": "https://www.wikidata.org/wiki/Q7202", "display_name": "Molecular biology", "level": 1, "score": 0.34718406200408936}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.3296070694923401}, {"id": "https://openalex.org/C136229726", "wikidata": "https://www.wikidata.org/wiki/Q327092", "display_name": "Biomedical engineering", "level": 1, "score": 0.3255264163017273}, {"id": "https://openalex.org/C105795698", "wikidata": "https://www.wikidata.org/wiki/Q12483", "display_name": "Statistics", "level": 1, "score": 0.2974625825881958}, {"id": "https://openalex.org/C43617362", "wikidata": "https://www.wikidata.org/wiki/Q170050", "display_name": "Chromatography", "level": 1, "score": 0.25805988907814026}, {"id": "https://openalex.org/C203014093", "wikidata": "https://www.wikidata.org/wiki/Q101929", "display_name": "Immunology", "level": 1, "score": 0.2525579333305359}, {"id": "https://openalex.org/C86803240", "wikidata": "https://www.wikidata.org/wiki/Q420", "display_name": "Biology", "level": 0, "score": 0.2474631667137146}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.22364965081214905}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.18421408534049988}, {"id": "https://openalex.org/C12554922", "wikidata": "https://www.wikidata.org/wiki/Q7100", "display_name": "Biophysics", "level": 1, "score": 0.09393656253814697}, {"id": "https://openalex.org/C114614502", "wikidata": "https://www.wikidata.org/wiki/Q76592", "display_name": "Combinatorics", "level": 1, "score": 0.09338480234146118}], "mesh": [{"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000191", "qualifier_name": "economics", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000191", "qualifier_name": "economics", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000191", "qualifier_name": "economics", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015496", "descriptor_name": "CD4-Positive T-Lymphocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D015496", "descriptor_name": "CD4-Positive T-Lymphocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D015496", "descriptor_name": "CD4-Positive T-Lymphocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000191", "qualifier_name": "economics", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000191", "qualifier_name": "economics", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000191", "qualifier_name": "economics", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D017493", "descriptor_name": "Leukocyte Common Antigens", "qualifier_ui": "Q000096", "qualifier_name": "biosynthesis", "is_major_topic": false}, {"descriptor_ui": "D017493", "descriptor_name": "Leukocyte Common Antigens", "qualifier_ui": "Q000096", "qualifier_name": "biosynthesis", "is_major_topic": false}, {"descriptor_ui": "D017493", "descriptor_name": "Leukocyte Common Antigens", "qualifier_ui": "Q000096", "qualifier_name": "biosynthesis", "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "doi:10.1002/cyto.10068", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/cyto.10068", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cyto.10068", "source": {"id": "https://openalex.org/S75647499", "display_name": "Cytometry", "issn_l": "0196-4763", "issn": ["0196-4763", "1097-0320"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Cytometry", "raw_type": "journal-article"}, {"id": "pmid:12116348", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/12116348", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Cytometry", "raw_type": null}], "best_oa_location": {"id": "doi:10.1002/cyto.10068", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/cyto.10068", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cyto.10068", "source": {"id": "https://openalex.org/S75647499", "display_name": "Cytometry", "issn_l": "0196-4763", "issn": ["0196-4763", "1097-0320"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Cytometry", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [{"id": "https://openalex.org/F4320307115", "display_name": "Bristol-Myers Squibb", "ror": "https://ror.org/00gtmwv55"}, {"id": "https://openalex.org/F4320320300", "display_name": "European Commission", "ror": "https://ror.org/00k4n6c32"}], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W2069198171.pdf", "grobid_xml": "https://content.openalex.org/works/W2069198171.grobid-xml"}, "referenced_works_count": 37, "referenced_works": ["https://openalex.org/W19281978", "https://openalex.org/W1784147363", "https://openalex.org/W1984448060", "https://openalex.org/W1994159439", "https://openalex.org/W1994898044", "https://openalex.org/W1999825111", "https://openalex.org/W2004182360", "https://openalex.org/W2005670282", "https://openalex.org/W2007493596", "https://openalex.org/W2014961664", "https://openalex.org/W2015795623", "https://openalex.org/W2025485262", "https://openalex.org/W2027411352", "https://openalex.org/W2039938554", "https://openalex.org/W2046803976", "https://openalex.org/W2050086746", "https://openalex.org/W2051959280", "https://openalex.org/W2053922392", "https://openalex.org/W2054304440", "https://openalex.org/W2054433315", "https://openalex.org/W2063010600", "https://openalex.org/W2065842764", "https://openalex.org/W2071600835", "https://openalex.org/W2086963323", "https://openalex.org/W2091025968", "https://openalex.org/W2091032431", "https://openalex.org/W2097568281", "https://openalex.org/W2101889723", "https://openalex.org/W2118800567", "https://openalex.org/W2119197472", "https://openalex.org/W2141302707", "https://openalex.org/W2146491048", "https://openalex.org/W2153069489", "https://openalex.org/W2326389485", "https://openalex.org/W2334996018", "https://openalex.org/W3006832735", "https://openalex.org/W4231253119"], "related_works": ["https://openalex.org/W108845024", "https://openalex.org/W57712237", "https://openalex.org/W2578985712", "https://openalex.org/W4300125793", "https://openalex.org/W2406961474", "https://openalex.org/W2143566611", "https://openalex.org/W1985641305", "https://openalex.org/W2094905172", "https://openalex.org/W2003237411", "https://openalex.org/W1717426641"], "abstract_inverted_index": {"BACKGROUND:": [0], "North": [1], "American": [2], "and": [3, 31, 77, 114, 139, 143, 159, 172, 179, 186, 200, 233, 315, 319], "European": [4], "guidelines": [5], "for": [6, 104, 119, 282], "dual-platform": [7], "(DP)": [8], "flow": [9, 42, 330], "cytometry": [10], "recommend": [11], "absolute": [12, 23, 110, 190], "CD4": [13, 111, 146, 191, 296], "T-cell": [14, 297], "counts": [15, 25, 72, 75, 147, 192, 253, 258], "to": [16, 168], "be": [17, 86, 271, 321], "calculated": [18], "from": [19], "two": [20, 60], "parameters:": [21], "the": [22, 32, 45, 59, 63, 80, 101, 106, 196, 221, 235, 260, 287, 304], "lymphocyte": [24, 154, 223, 257], "obtained": [26, 40], "on": [27, 284, 323], "a": [28, 51, 140, 294], "hematology": [29, 285], "analyzer": [30, 328], "percentages": [33], "of": [34, 47, 66, 108, 145, 189, 218, 326], "CD4+": [35], "cells": [36], "among": [37, 79], "lymphocytes": [38, 48], "(CD4%/lympho)": [39], "by": [41, 131], "cytometry.": [43], "Nevertheless,": [44], "identification": [46], "is": [49, 62, 300], "error-prone:": [50], "poor": [52], "match": [53], "between": [54, 195], "these": [55], "common": [56, 102], "denominators": [57], "in": [58], "systems": [61], "main": [64], "source": [65], "inaccuracy.": [67], "In": [68], "contrast,": [69], "total": [70, 98], "leucocyte": [71, 252], "(white": [73], "cell": [74], "[WCC])": [76], "CD4%": [78], "gated": [81], "CD45+": [82], "leucocytes": [83, 99], "(CD4%/leuco)": [84], "can": [85, 320], "determined": [87], "with": [88, 153, 220, 234, 279, 290], "greater": [89], "accuracy.": [90], "METHODS:": [91], "We": [92], "introduced": [93], "\"PanLeucogating,\"": [94], "i.e.,": [95], "we": [96], "used": [97, 118, 167], "as": [100, 259, 267, 301, 303], "denominator": [103], "improving": [105], "precision": [107, 144, 188], "DP": [109, 170, 201, 222, 251, 288, 309], "counting.": [112], "Correlations": [113], "Bland-Altman": [115], "tests": [116], "were": [117, 129, 148, 166, 193], "statistical": [120], "analysis.": [121], "RESULTS:": [122], "First,": [123], "22": [124], "stabilized": [125], "blood": [126, 164], "product": [127], "samples": [128, 165], "provided": [130, 273], "U.K.": [132], "National": [133], "External": [134], "Quality": [135], "Assessment": [136], "Scheme": [137], "(NEQAS)": [138], "higher": [141], "accuracy": [142], "documented": [149], "using": [150], "PanLeucogating": [151, 202, 292], "compared": [152], "gating.": [155], "Next,": [156], "183": [157], "fresh": [158], "112": [160], "fixed": [161], "(TransFix)": [162], "whole": [163], "compare": [169], "methods": [171], "single-platform": [173], "(SP)": [174], "methodology,": [175], "including": [176], "both": [177], "volumetric": [178, 198, 213, 306], "bead-based": [180, 237], "techniques.": [181], "A": [182], "particularly": [183], "high": [184], "correlation": [185], "comparable": [187], "observed": [194], "SP": [197, 212, 236, 305], "method": [199, 214, 238, 289, 310], "(R(2)": [203, 225, 239], "=": [204, 226, 240], "0.990;": [205], "bias": [206, 228, 242], "6": [207], "+/-": [208, 230], "SD": [209, 231], "17%).": [210], "The": [211], "showed": [215], "lower": [216], "levels": [217], "agreement": [219], "gating": [224], "0.758;": [227], "14": [229], "51%)": [232], "0.923;": [241], "4": [243], "+/-SD": [244], "31%).": [245], "CONCLUSIONS:": [246], "These": [247], "observations": [248], "show": [249], "that": [250, 299], "(WCC)": [254], "should": [255], "replace": [256], "\"common": [261], "denominator\"": [262], "although": [263], "CD4%/lympho": [264], "values": [265], "can,": [266], "an": [268], "extra": [269], "step,": [270], "also": [272], "readily": [274], "if": [275], "requested.": [276], "When": [277], "coupled": [278], "quality": [280], "control": [281], "WCC": [283], "analyzers,": [286], "CD45": [291, 314], "represents": [293], "robust": [295], "assay": [298], "accurate": [302], "technique.": [307], "This": [308], "uses": [311], "only": [312], "two,": [313], "CD4,": [316], "antibody": [317], "reagents": [318], "run": [322], "any": [324], "pair": [325], "hematological": [327], "plus": [329], "cytometer.": [331]}, "counts_by_year": [{"year": 2026, "cited_by_count": 1}, {"year": 2025, "cited_by_count": 1}, {"year": 2021, "cited_by_count": 2}, {"year": 2020, "cited_by_count": 2}, {"year": 2019, "cited_by_count": 2}, {"year": 2018, "cited_by_count": 6}, {"year": 2017, "cited_by_count": 6}, {"year": 2016, "cited_by_count": 3}, {"year": 2015, "cited_by_count": 9}, {"year": 2014, "cited_by_count": 8}, {"year": 2013, "cited_by_count": 6}, {"year": 2012, "cited_by_count": 9}], "updated_date": "2026-04-29T09:16:38.111599", "created_date": "2016-06-24T00:00:00"}, {"id": "https://openalex.org/W2163030587", "doi": "https://doi.org/10.1371/journal.pone.0141311", "title": "Accuracy of a New Platelet Count System (PLT-F) Depends on the Staining Property of Its Reagents", "display_name": "Accuracy of a New Platelet Count System (PLT-F) Depends on the Staining Property of Its Reagents", "relevance_score": 84.353775, "publication_year": 2015, "publication_date": "2015-10-23", "ids": {"openalex": "https://openalex.org/W2163030587", "doi": "https://doi.org/10.1371/journal.pone.0141311", "mag": "2163030587", "pmid": "https://pubmed.ncbi.nlm.nih.gov/26496387"}, "language": "en", "primary_location": {"id": "doi:10.1371/journal.pone.0141311", "is_oa": true, "landing_page_url": "https://doi.org/10.1371/journal.pone.0141311", "pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0141311&type=printable", "source": {"id": "https://openalex.org/S202381698", "display_name": "PLoS ONE", "issn_l": "1932-6203", "issn": ["1932-6203"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310315706", "host_organization_name": "Public Library of Science", "host_organization_lineage": ["https://openalex.org/P4310315706"], "host_organization_lineage_names": ["Public Library of Science"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "PLOS ONE", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "doaj", "pubmed"], "open_access": {"is_oa": true, "oa_status": "gold", "oa_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0141311&type=printable", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5102711824", "display_name": "Atsushi Wada", "orcid": "https://orcid.org/0000-0002-0530-7701"}, "institutions": [{"id": "https://openalex.org/I54594937", "display_name": "Sysmex (Japan)", "ror": "https://ror.org/00gfstq19", "country_code": "JP", "type": "company", "lineage": ["https://openalex.org/I54594937"]}], "countries": ["JP"], "is_corresponding": true, "raw_author_name": "Atsushi Wada", "raw_affiliation_strings": ["Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}, {"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5017586300", "display_name": "Yuri Takagi", "orcid": null}, "institutions": [{"id": "https://openalex.org/I54594937", "display_name": "Sysmex (Japan)", "ror": "https://ror.org/00gfstq19", "country_code": "JP", "type": "company", "lineage": ["https://openalex.org/I54594937"]}], "countries": ["JP"], "is_corresponding": false, "raw_author_name": "Yuri Takagi", "raw_affiliation_strings": ["Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}, {"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5007380249", "display_name": "Mari Kono", "orcid": "https://orcid.org/0000-0002-7646-9118"}, "institutions": [{"id": "https://openalex.org/I54594937", "display_name": "Sysmex (Japan)", "ror": "https://ror.org/00gfstq19", "country_code": "JP", "type": "company", "lineage": ["https://openalex.org/I54594937"]}], "countries": ["JP"], "is_corresponding": false, "raw_author_name": "Mari Kono", "raw_affiliation_strings": ["Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}, {"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5048811146", "display_name": "Takashi Morikawa", "orcid": "https://orcid.org/0000-0003-4445-9270"}, "institutions": [{"id": "https://openalex.org/I54594937", "display_name": "Sysmex (Japan)", "ror": "https://ror.org/00gfstq19", "country_code": "JP", "type": "company", "lineage": ["https://openalex.org/I54594937"]}], "countries": ["JP"], "is_corresponding": false, "raw_author_name": "Takashi Morikawa", "raw_affiliation_strings": ["Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}, {"raw_affiliation_string": "Scientific Research Division, Scientific Affairs, Sysmex Corporation, 1-3-2 Murotani, Nishi-ku, Kobe, Hyogo 651\u20132241, Japan", "institution_ids": ["https://openalex.org/I54594937"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 4, "corresponding_author_ids": ["https://openalex.org/A5102711824"], "corresponding_institution_ids": ["https://openalex.org/I54594937"], "apc_list": {"value": 1805, "currency": "USD", "value_usd": 1805}, "apc_paid": {"value": 1805, "currency": "USD", "value_usd": 1805}, "fwci": 1.4432, "has_fulltext": true, "cited_by_count": 55, "citation_normalized_percentile": {"value": 0.83759478, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 94, "max": 99}, "biblio": {"volume": "10", "issue": "10", "first_page": "e0141311", "last_page": "e0141311"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11355", "display_name": "Inflammatory Biomarkers in Disease Prognosis", "score": 0.40049999952316284, "subfield": {"id": "https://openalex.org/subfields/2730", "display_name": "Oncology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11355", "display_name": "Inflammatory Biomarkers in Disease Prognosis", "score": 0.40049999952316284, "subfield": {"id": "https://openalex.org/subfields/2730", "display_name": "Oncology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T10746", "display_name": "Platelet Disorders and Treatments", "score": 0.22030000388622284, "subfield": {"id": "https://openalex.org/subfields/2720", "display_name": "Hematology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.21369999647140503, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/platelet", "display_name": "Platelet", "score": 0.924081563949585}, {"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.8118417263031006}, {"id": "https://openalex.org/keywords/flow-cytometry", "display_name": "Flow cytometry", "score": 0.6045628786087036}, {"id": "https://openalex.org/keywords/staining", "display_name": "Staining", "score": 0.5824750661849976}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.5100207924842834}, {"id": "https://openalex.org/keywords/paraformaldehyde", "display_name": "Paraformaldehyde", "score": 0.4696447253227234}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.45486798882484436}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.4511220157146454}, {"id": "https://openalex.org/keywords/cd63", "display_name": "CD63", "score": 0.42636987566947937}, {"id": "https://openalex.org/keywords/immunology", "display_name": "Immunology", "score": 0.31955486536026}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.3169175684452057}, {"id": "https://openalex.org/keywords/biochemistry", "display_name": "Biochemistry", "score": 0.11930689215660095}], "concepts": [{"id": "https://openalex.org/C89560881", "wikidata": "https://www.wikidata.org/wiki/Q101026", "display_name": "Platelet", "level": 2, "score": 0.924081563949585}, {"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.8118417263031006}, {"id": "https://openalex.org/C553184892", "wikidata": "https://www.wikidata.org/wiki/Q1141429", "display_name": "Flow cytometry", "level": 2, "score": 0.6045628786087036}, {"id": "https://openalex.org/C74864618", "wikidata": "https://www.wikidata.org/wiki/Q2332446", "display_name": "Staining", "level": 2, "score": 0.5824750661849976}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.5100207924842834}, {"id": "https://openalex.org/C2778723968", "wikidata": "https://www.wikidata.org/wiki/Q418566", "display_name": "Paraformaldehyde", "level": 2, "score": 0.4696447253227234}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.45486798882484436}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.4511220157146454}, {"id": "https://openalex.org/C2776385711", "wikidata": "https://www.wikidata.org/wiki/Q4035583", "display_name": "CD63", "level": 5, "score": 0.42636987566947937}, {"id": "https://openalex.org/C203014093", "wikidata": "https://www.wikidata.org/wiki/Q101929", "display_name": "Immunology", "level": 1, "score": 0.31955486536026}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.3169175684452057}, {"id": "https://openalex.org/C55493867", "wikidata": "https://www.wikidata.org/wiki/Q7094", "display_name": "Biochemistry", "level": 1, "score": 0.11930689215660095}, {"id": "https://openalex.org/C20518536", "wikidata": "https://www.wikidata.org/wiki/Q6840469", "display_name": "Microvesicles", "level": 4, "score": 0.0}, {"id": "https://openalex.org/C104317684", "wikidata": "https://www.wikidata.org/wiki/Q7187", "display_name": "Gene", "level": 2, "score": 0.0}, {"id": "https://openalex.org/C145059251", "wikidata": "https://www.wikidata.org/wiki/Q310899", "display_name": "microRNA", "level": 3, "score": 0.0}], "mesh": [{"descriptor_ui": "D001792", "descriptor_name": "Blood Platelets", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D001792", "descriptor_name": "Blood Platelets", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D001792", "descriptor_name": "Blood Platelets", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D005456", "descriptor_name": "Fluorescent Dyes", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D005456", "descriptor_name": "Fluorescent Dyes", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D005456", "descriptor_name": "Fluorescent Dyes", "qualifier_ui": "Q000737", "qualifier_name": "chemistry", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D010976", "descriptor_name": "Platelet Count", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D010976", "descriptor_name": "Platelet Count", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D010976", "descriptor_name": "Platelet Count", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D011933", "descriptor_name": "Reagent Kits, Diagnostic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011933", "descriptor_name": "Reagent Kits, Diagnostic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011933", "descriptor_name": "Reagent Kits, Diagnostic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013194", "descriptor_name": "Staining and Labeling", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013194", "descriptor_name": "Staining and Labeling", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013194", "descriptor_name": "Staining and Labeling", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D039661", "descriptor_name": "Integrin beta3", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D039661", "descriptor_name": "Integrin beta3", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D039661", "descriptor_name": "Integrin beta3", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D040201", "descriptor_name": "Platelet Membrane Glycoprotein IIb", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D040201", "descriptor_name": "Platelet Membrane Glycoprotein IIb", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D040201", "descriptor_name": "Platelet Membrane Glycoprotein IIb", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}], "locations_count": 5, "locations": [{"id": "doi:10.1371/journal.pone.0141311", "is_oa": true, "landing_page_url": "https://doi.org/10.1371/journal.pone.0141311", "pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0141311&type=printable", "source": {"id": "https://openalex.org/S202381698", "display_name": "PLoS ONE", "issn_l": "1932-6203", "issn": ["1932-6203"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310315706", "host_organization_name": "Public Library of Science", "host_organization_lineage": ["https://openalex.org/P4310315706"], "host_organization_lineage_names": ["Public Library of Science"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "PLOS ONE", "raw_type": "journal-article"}, {"id": "pmid:26496387", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/26496387", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "PloS one", "raw_type": null}, {"id": "pmh:oai:doaj.org/article:fc1f68ddf21c471dac81d5d309e30a71", "is_oa": false, "landing_page_url": "https://doaj.org/article/fc1f68ddf21c471dac81d5d309e30a71", "pdf_url": null, "source": {"id": "https://openalex.org/S4306401280", "display_name": "DOAJ (DOAJ: Directory of Open Access Journals)", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "PLoS ONE, Vol 10, Iss 10, p e0141311 (2015)", "raw_type": "article"}, {"id": "pmh:oai:figshare.com:article/1584343", "is_oa": true, "landing_page_url": "https://figshare.com/articles/dataset/_Accuracy_of_a_New_Platelet_Count_System_PLT_F_Depends_on_the_Staining_Property_of_Its_Reagents_/1584343", "pdf_url": null, "source": {"id": "https://openalex.org/S4377196282", "display_name": "Figshare", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I4210132348", "host_organization_name": "Figshare (United Kingdom)", "host_organization_lineage": ["https://openalex.org/I4210132348"], "host_organization_lineage_names": [], "type": "repository"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "", "raw_type": "Dataset"}, {"id": "pmh:oai:pubmedcentral.nih.gov:4619826", "is_oa": true, "landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/4619826", "pdf_url": null, "source": {"id": "https://openalex.org/S2764455111", "display_name": "PubMed Central", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "PLoS One", "raw_type": "Text"}], "best_oa_location": {"id": "doi:10.1371/journal.pone.0141311", "is_oa": true, "landing_page_url": "https://doi.org/10.1371/journal.pone.0141311", "pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0141311&type=printable", "source": {"id": "https://openalex.org/S202381698", "display_name": "PLoS ONE", "issn_l": "1932-6203", "issn": ["1932-6203"], "is_oa": true, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310315706", "host_organization_name": "Public Library of Science", "host_organization_lineage": ["https://openalex.org/P4310315706"], "host_organization_lineage_names": ["Public Library of Science"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "PLOS ONE", "raw_type": "journal-article"}, "sustainable_development_goals": [{"display_name": "Reduced inequalities", "id": "https://metadata.un.org/sdg/10", "score": 0.6299999952316284}], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W2163030587.pdf", "grobid_xml": "https://content.openalex.org/works/W2163030587.grobid-xml"}, "referenced_works_count": 30, "referenced_works": ["https://openalex.org/W8249067", "https://openalex.org/W163744583", "https://openalex.org/W1491448463", "https://openalex.org/W1581255805", "https://openalex.org/W1901245148", "https://openalex.org/W1902991162", "https://openalex.org/W1981923760", "https://openalex.org/W1992604276", "https://openalex.org/W2007002791", "https://openalex.org/W2013052620", "https://openalex.org/W2017631280", "https://openalex.org/W2023376918", "https://openalex.org/W2023538885", "https://openalex.org/W2030380325", "https://openalex.org/W2035633239", "https://openalex.org/W2047137615", "https://openalex.org/W2068010235", "https://openalex.org/W2076405482", "https://openalex.org/W2092803321", "https://openalex.org/W2096638818", "https://openalex.org/W2121960517", "https://openalex.org/W2125322011", "https://openalex.org/W2125720715", "https://openalex.org/W2130364846", "https://openalex.org/W2139125156", "https://openalex.org/W2142178373", "https://openalex.org/W2143887475", "https://openalex.org/W2327625073", "https://openalex.org/W2591717879", "https://openalex.org/W4252116686"], "related_works": ["https://openalex.org/W1990656788", "https://openalex.org/W2586074170", "https://openalex.org/W2360254475", "https://openalex.org/W1993046381", "https://openalex.org/W3214917081", "https://openalex.org/W2370417582", "https://openalex.org/W2091604563", "https://openalex.org/W2367654780", "https://openalex.org/W2371118960", "https://openalex.org/W2163030587"], "abstract_inverted_index": {"BACKGROUND:": [0], "Platelet": [1], "count": [2, 16, 25, 59], "is": [3], "essential": [4], "for": [5], "the": [6, 46, 67, 146, 182, 186, 200, 204], "diagnosis": [7], "and": [8, 86, 104, 113, 152, 156, 174, 192], "management": [9], "of": [10, 149, 163, 185, 203], "hemostasis": [11], "abnormalities.": [12], "Although": [13], "existing": [14], "platelet": [15, 58, 69], "methods": [17], "installed": [18], "in": [19, 27, 36, 45, 62, 79, 130], "common": [20], "hematology": [21, 48, 94], "analyzers": [22], "can": [23], "correctly": [24, 127], "platelets": [26, 35, 129, 151, 191], "normal": [28], "blood": [29], "samples,": [30], "they": [31], "tend": [32], "to": [33, 54, 199], "miscount": [34], "some": [37, 136], "abnormal": [38, 63], "samples.": [39, 64], "The": [40, 96, 124], "newly": [41], "developed": [42], "PLT-F": [43, 68, 102, 125, 187, 205], "channel": [44], "XN-Series": [47], "analyzer": [49], "(Sysmex)": [50], "has": [51, 75], "been": [52, 77], "reported": [53], "be": [55], "a": [56], "reliable": [57], "system,": [60], "even": [61], "However,": [65], "how": [66], "counting": [70], "system": [71, 126], "achieves": [72], "such": [73], "accuracy": [74, 202], "not": [76], "described": [78], "scientific": [80], "articles.": [81], "METHODS:": [82], "Isolated": [83], "platelets,": [84], "erythrocytes,": [85], "fragmented": [87, 193], "erythrocytes": [88, 194], "were": [89, 98, 168], "examined": [90], "using": [91, 115], "an": [92], "automated": [93], "analyzer.": [95], "samples": [97], "labeled": [99, 139, 170], "by": [100, 189], "combining": [101], "reagents": [103, 133], "anti-CD62p,": [105], "CD63,": [106], "Grp75,": [107], "Calreticulin,": [108], "CD41,": [109], "or": [110, 120], "CD61": [111], "antibody,": [112], "analyzed": [114], "confocal": [116], "laser": [117], "scanning": [118], "microscopy": [119], "flow": [121, 157], "cytometry.": [122], "RESULTS:": [123], "discriminated": [128], "erythrocytes.": [131, 153], "Its": [132], "strongly": [134, 165], "stained": [135, 145, 166], "intraplatelet": [137], "organelles": [138], "with": [140, 171], "anti-Grp75,": [141], "but": [142], "only": [143], "faintly": [144], "plasma": [147], "membrane": [148], "both": [150], "Microscopic": [154], "observation": [155], "cytometric": [158], "examination": [159], "revealed": [160, 180], "that": [161, 181], "all": [162], "these": [164], "cells": [167], "also": [169], "platelet-specific": [172], "anti-CD41": [173], "anti-CD61": [175], "antibodies.": [176], "CONCLUSIONS:": [177], "This": [178], "study": [179], "staining": [183], "property": [184], "reagents,": [188], "which": [190], "are": [195], "clearly": [196], "distinguished,": [197], "contributes": [198], "platelet-counting": [201], "system.": [206]}, "counts_by_year": [{"year": 2026, "cited_by_count": 3}, {"year": 2025, "cited_by_count": 8}, {"year": 2024, "cited_by_count": 5}, {"year": 2023, "cited_by_count": 4}, {"year": 2022, "cited_by_count": 2}, {"year": 2021, "cited_by_count": 7}, {"year": 2020, "cited_by_count": 8}, {"year": 2019, "cited_by_count": 7}, {"year": 2018, "cited_by_count": 4}, {"year": 2017, "cited_by_count": 3}, {"year": 2016, "cited_by_count": 3}], "updated_date": "2026-05-06T08:25:59.206177", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W107382872", "doi": "https://doi.org/10.5858/2001-125-0391-tnhasx", "title": "The new hematology analyzer Sysmex XE-2100: performance evaluation of a novel white blood cell differential technology.", "display_name": "The new hematology analyzer Sysmex XE-2100: performance evaluation of a novel white blood cell differential technology.", "relevance_score": 78.63791, "publication_year": 2001, "publication_date": "2001-03-01", "ids": {"openalex": "https://openalex.org/W107382872", "doi": "https://doi.org/10.5858/2001-125-0391-tnhasx", "mag": "107382872", "pmid": "https://pubmed.ncbi.nlm.nih.gov/11231489"}, "language": "en", "primary_location": {"id": "pmid:11231489", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/11231489", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of pathology & laboratory medicine", "raw_type": null}, "type": "article", "indexed_in": ["pubmed"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5007415930", "display_name": "Katharina Ruzicka", "orcid": null}, "institutions": [{"id": "https://openalex.org/I129774422", "display_name": "University of Vienna", "ror": "https://ror.org/03prydq77", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I129774422"]}], "countries": ["AT"], "is_corresponding": true, "raw_author_name": "K Ruzicka", "raw_affiliation_strings": ["Department of Laboratory Medicine, University of Vienna, Austria", "Department of Laboratory Medicine, University of Vienna, Austria,"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Laboratory Medicine, University of Vienna, Austria", "institution_ids": ["https://openalex.org/I129774422"]}, {"raw_affiliation_string": "Department of Laboratory Medicine, University of Vienna, Austria,", "institution_ids": ["https://openalex.org/I129774422"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5077182872", "display_name": "Mario Veitl", "orcid": null}, "institutions": [{"id": "https://openalex.org/I129774422", "display_name": "University of Vienna", "ror": "https://ror.org/03prydq77", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I129774422"]}, {"id": "https://openalex.org/I76134821", "display_name": "Medical University of Vienna", "ror": "https://ror.org/05n3x4p02", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I76134821"]}], "countries": ["AT"], "is_corresponding": false, "raw_author_name": "M Veitl", "raw_affiliation_strings": ["From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria", "institution_ids": ["https://openalex.org/I129774422", "https://openalex.org/I76134821"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5025437291", "display_name": "Renate Thalhammer-Scherrer", "orcid": null}, "institutions": [{"id": "https://openalex.org/I129774422", "display_name": "University of Vienna", "ror": "https://ror.org/03prydq77", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I129774422"]}, {"id": "https://openalex.org/I76134821", "display_name": "Medical University of Vienna", "ror": "https://ror.org/05n3x4p02", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I76134821"]}], "countries": ["AT"], "is_corresponding": false, "raw_author_name": "R Thalhammer-Scherrer", "raw_affiliation_strings": ["From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria", "institution_ids": ["https://openalex.org/I129774422", "https://openalex.org/I76134821"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5072208578", "display_name": "Ilse Schwarzinger", "orcid": "https://orcid.org/0000-0001-8250-6520"}, "institutions": [{"id": "https://openalex.org/I76134821", "display_name": "Medical University of Vienna", "ror": "https://ror.org/05n3x4p02", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I76134821"]}], "countries": ["AT"], "is_corresponding": false, "raw_author_name": "I Schwarzinger", "raw_affiliation_strings": ["Reprints: Ilse Schwarzinger, MD, Department of Laboratory Medicine, University of Vienna, W\u00e4hringer G\u00fcrtel 18-20, A-1090, Vienna, Austria ()"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Reprints: Ilse Schwarzinger, MD, Department of Laboratory Medicine, University of Vienna, W\u00e4hringer G\u00fcrtel 18-20, A-1090, Vienna, Austria ()", "institution_ids": ["https://openalex.org/I76134821"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 4, "corresponding_author_ids": ["https://openalex.org/A5007415930"], "corresponding_institution_ids": ["https://openalex.org/I129774422"], "apc_list": null, "apc_paid": null, "fwci": 1.5454, "has_fulltext": false, "cited_by_count": 100, "citation_normalized_percentile": {"value": 0.80965769, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 90, "max": 100}, "biblio": {"volume": "125", "issue": "3", "first_page": "391", "last_page": "6"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9283999800682068, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9283999800682068, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.014700000174343586, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.012900000438094139, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.8923215270042419}, {"id": "https://openalex.org/keywords/white-blood-cell", "display_name": "White blood cell", "score": 0.7521356344223022}, {"id": "https://openalex.org/keywords/flagging", "display_name": "Flagging", "score": 0.7210869193077087}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.568468451499939}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.4787668287754059}, {"id": "https://openalex.org/keywords/blood-cell", "display_name": "Blood cell", "score": 0.4736058712005615}, {"id": "https://openalex.org/keywords/context", "display_name": "Context (archaeology)", "score": 0.4469906687736511}, {"id": "https://openalex.org/keywords/nuclear-medicine", "display_name": "Nuclear medicine", "score": 0.4085654616355896}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.3849923014640808}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.3152337074279785}, {"id": "https://openalex.org/keywords/biology", "display_name": "Biology", "score": 0.13333064317703247}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.8923215270042419}, {"id": "https://openalex.org/C2778488018", "wikidata": "https://www.wikidata.org/wiki/Q42395", "display_name": "White blood cell", "level": 2, "score": 0.7521356344223022}, {"id": "https://openalex.org/C2777548347", "wikidata": "https://www.wikidata.org/wiki/Q5456937", "display_name": "Flagging", "level": 2, "score": 0.7210869193077087}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.568468451499939}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.4787668287754059}, {"id": "https://openalex.org/C2779979121", "wikidata": "https://www.wikidata.org/wiki/Q211709", "display_name": "Blood cell", "level": 2, "score": 0.4736058712005615}, {"id": "https://openalex.org/C2779343474", "wikidata": "https://www.wikidata.org/wiki/Q3109175", "display_name": "Context (archaeology)", "level": 2, "score": 0.4469906687736511}, {"id": "https://openalex.org/C2989005", "wikidata": "https://www.wikidata.org/wiki/Q214963", "display_name": "Nuclear medicine", "level": 1, "score": 0.4085654616355896}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.3849923014640808}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.3152337074279785}, {"id": "https://openalex.org/C86803240", "wikidata": "https://www.wikidata.org/wiki/Q420", "display_name": "Biology", "level": 0, "score": 0.13333064317703247}, {"id": "https://openalex.org/C166957645", "wikidata": "https://www.wikidata.org/wiki/Q23498", "display_name": "Archaeology", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C151730666", "wikidata": "https://www.wikidata.org/wiki/Q7205", "display_name": "Paleontology", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C95457728", "wikidata": "https://www.wikidata.org/wiki/Q309", "display_name": "History", "level": 0, "score": 0.0}], "mesh": [{"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D004900", "descriptor_name": "Erythroblasts", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D004900", "descriptor_name": "Erythroblasts", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D004900", "descriptor_name": "Erythroblasts", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D004906", "descriptor_name": "Erythrocyte Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D004906", "descriptor_name": "Erythrocyte Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D004906", "descriptor_name": "Erythrocyte Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D005188", "descriptor_name": "False Negative Reactions", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005188", "descriptor_name": "False Negative Reactions", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005188", "descriptor_name": "False Negative Reactions", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005189", "descriptor_name": "False Positive Reactions", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005189", "descriptor_name": "False Positive Reactions", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005189", "descriptor_name": "False Positive Reactions", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D007958", "descriptor_name": "Leukocyte Count", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D007962", "descriptor_name": "Leukocytes", "qualifier_ui": "Q000473", "qualifier_name": "pathology", "is_major_topic": false}, {"descriptor_ui": "D007962", "descriptor_name": "Leukocytes", "qualifier_ui": "Q000473", "qualifier_name": "pathology", "is_major_topic": false}, {"descriptor_ui": "D007962", "descriptor_name": "Leukocytes", "qualifier_ui": "Q000473", "qualifier_name": "pathology", "is_major_topic": false}, {"descriptor_ui": "D012680", "descriptor_name": "Sensitivity and Specificity", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012680", "descriptor_name": "Sensitivity and Specificity", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012680", "descriptor_name": "Sensitivity and Specificity", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "pmid:11231489", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/11231489", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of pathology & laboratory medicine", "raw_type": null}, {"id": "mag:107382872", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/11231489/", "pdf_url": null, "source": {"id": "https://openalex.org/S139062638", "display_name": "Archives of Pathology & Laboratory Medicine", "issn_l": "0003-9985", "issn": ["0003-9985", "1543-2165"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320259", "host_organization_name": "American Medical Association", "host_organization_lineage": ["https://openalex.org/P4310320259"], "host_organization_lineage_names": ["American Medical Association"], "type": "journal"}, "license": null, "license_id": null, "version": null, "is_accepted": false, "is_published": null, "raw_source_name": "Archives of Pathology & Laboratory Medicine", "raw_type": null}], "best_oa_location": null, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 20, "referenced_works": ["https://openalex.org/W35565491", "https://openalex.org/W68602231", "https://openalex.org/W1909632531", "https://openalex.org/W1978892637", "https://openalex.org/W1980090876", "https://openalex.org/W2000199207", "https://openalex.org/W2044127972", "https://openalex.org/W2056703613", "https://openalex.org/W2068953235", "https://openalex.org/W2086124279", "https://openalex.org/W2090338522", "https://openalex.org/W2123695478", "https://openalex.org/W2136978454", "https://openalex.org/W2141441177", "https://openalex.org/W2161004488", "https://openalex.org/W2163385433", "https://openalex.org/W2187001514", "https://openalex.org/W2189033549", "https://openalex.org/W2315254983", "https://openalex.org/W2335099826"], "related_works": ["https://openalex.org/W2137615559", "https://openalex.org/W2081112601", "https://openalex.org/W2025031772", "https://openalex.org/W2061357093", "https://openalex.org/W2414722065", "https://openalex.org/W2109417222", "https://openalex.org/W2097049686", "https://openalex.org/W2020912886", "https://openalex.org/W2593173846", "https://openalex.org/W2150258149", "https://openalex.org/W2056735404", "https://openalex.org/W1923273815", "https://openalex.org/W2080266381", "https://openalex.org/W3087305911", "https://openalex.org/W2327625073", "https://openalex.org/W2150565580", "https://openalex.org/W2150444494", "https://openalex.org/W2006488016", "https://openalex.org/W1989608827", "https://openalex.org/W2358734404"], "abstract_inverted_index": {"CONTEXT:": [0], "The": [1, 129, 149], "new": [2, 183], "hematology": [3, 65], "analyzer": [4, 66], "Sysmex": [5, 40, 67, 177], "XE-2100": [6, 41, 100, 191], "(TOA": [7, 69], "Medical": [8, 70], "Electronics,": [9], "Kobe,": [10], "Japan)": [11], "has": [12], "a": [13, 22, 193], "novel,": [14], "combined,": [15], "white": [16, 93, 140, 184, 202], "blood": [17, 30, 76, 94, 141, 157, 185, 203], "cell": [18, 95, 158, 186], "differential": [19, 96, 187], "technology": [20, 188], "and": [21, 53, 56, 83, 112, 118, 123, 146, 153, 169], "special": [23], "reagent": [24], "system": [25], "to": [26, 43], "enumerate": [27], "nucleated": [28, 155], "red": [29, 156], "cells.": [31, 204], "DESIGN:": [32], "Performance": [33], "evaluation": [34, 168], "of": [35, 38, 47, 58, 86, 132, 137, 151, 176, 189, 200], "both": [36], "technologies": [37], "the": [39, 44, 48, 59, 64, 87, 99, 105, 135, 166, 182, 190], "according": [42], "H20-A": [45], "protocol": [46], "National": [49], "Committee": [50], "for": [51, 63, 109, 121, 134], "Clinical": [52], "Laboratory": [54], "Standards": [55], "comparison": [57], "results": [60], "with": [61, 104, 173], "those": [62], "NE-8000": [68], "Electronics).": [71], "SPECIMENS:": [72], "Five": [73], "hundred": [74], "forty-four": [75], "samples": [77], "randomly": [78], "chosen": [79], "from": [80], "various": [81], "inpatient": [82], "outpatient": [84], "departments": [85], "Vienna": [88], "University": [89], "hospital.": [90], "RESULTS:": [91], "Five-part": [92], "counts": [97, 159], "on": [98], "revealed": [101], "excellent": [102, 161], "correlation": [103, 120, 150], "manual": [106], "reference": [107], "method": [108], "neutrophils,": [110], "lymphocytes,": [111], "eosinophils": [113], "(r": [114, 125, 162], "=.925,.922,": [115], "and.877,": [116], "respectively)": [117], "good": [119], "monocytes": [122], "basophils": [124], "=.756": [126], "and.763,": [127], "respectively).": [128], "efficiency": [130], "rates": [131], "flagging": [133, 199], "presence": [136], ">/=1%": [138], "abnormal": [139, 201], "cells": [142], "were": [143], "83%": [144], "(XE-2100)": [145], "66%": [147], "(NE-8000).": [148], "automated": [152], "microscopic": [154], "was": [160], "=.97).": [163], "CONCLUSIONS:": [164], "From": [165], "present": [167], "our": [170], "former": [171], "experience": [172], "other": [174], "types": [175], "analyzers,": [178], "we": [179], "conclude": [180], "that": [181], "represents": [192], "further": [194], "development": [195], "toward": [196], "more": [197], "efficient": [198]}, "counts_by_year": [{"year": 2025, "cited_by_count": 2}, {"year": 2023, "cited_by_count": 3}, {"year": 2022, "cited_by_count": 1}, {"year": 2021, "cited_by_count": 4}, {"year": 2020, "cited_by_count": 2}, {"year": 2019, "cited_by_count": 4}, {"year": 2018, "cited_by_count": 3}, {"year": 2017, "cited_by_count": 4}, {"year": 2016, "cited_by_count": 6}, {"year": 2015, "cited_by_count": 4}, {"year": 2014, "cited_by_count": 14}, {"year": 2013, "cited_by_count": 10}, {"year": 2012, "cited_by_count": 5}], "updated_date": "2026-04-28T06:04:28.489925", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W2137615559", "doi": "https://doi.org/10.5858/2001-125-0391-tnhasx", "title": "The New Hematology Analyzer Sysmex XE-2100", "display_name": "The New Hematology Analyzer Sysmex XE-2100", "relevance_score": 77.972984, "publication_year": 2001, "publication_date": "2001-03-01", "ids": {"openalex": "https://openalex.org/W2137615559", "doi": "https://doi.org/10.5858/2001-125-0391-tnhasx", "mag": "2137615559"}, "language": "en", "primary_location": {"id": "doi:10.5858/2001-125-0391-tnhasx", "is_oa": false, "landing_page_url": "https://doi.org/10.5858/2001-125-0391-tnhasx", "pdf_url": null, "source": {"id": "https://openalex.org/S139062638", "display_name": "Archives of Pathology & Laboratory Medicine", "issn_l": "0003-9985", "issn": ["0003-9985", "1543-2165"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320259", "host_organization_name": "American Medical Association", "host_organization_lineage": ["https://openalex.org/P4310320259"], "host_organization_lineage_names": ["American Medical Association"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of Pathology &amp; Laboratory Medicine", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5007415930", "display_name": "Katharina Ruzicka", "orcid": null}, "institutions": [{"id": "https://openalex.org/I129774422", "display_name": "University of Vienna", "ror": "https://ror.org/03prydq77", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I129774422"]}, {"id": "https://openalex.org/I76134821", "display_name": "Medical University of Vienna", "ror": "https://ror.org/05n3x4p02", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I76134821"]}], "countries": ["AT"], "is_corresponding": false, "raw_author_name": "Katharina Ruzicka", "raw_affiliation_strings": ["From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria"], "affiliations": [{"raw_affiliation_string": "From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria", "institution_ids": ["https://openalex.org/I129774422", "https://openalex.org/I76134821"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5077182872", "display_name": "Mario Veitl", "orcid": null}, "institutions": [{"id": "https://openalex.org/I129774422", "display_name": "University of Vienna", "ror": "https://ror.org/03prydq77", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I129774422"]}, {"id": "https://openalex.org/I76134821", "display_name": "Medical University of Vienna", "ror": "https://ror.org/05n3x4p02", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I76134821"]}], "countries": ["AT"], "is_corresponding": false, "raw_author_name": "Mario Veitl", "raw_affiliation_strings": ["From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria"], "affiliations": [{"raw_affiliation_string": "From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria", "institution_ids": ["https://openalex.org/I129774422", "https://openalex.org/I76134821"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5025437291", "display_name": "Renate Thalhammer-Scherrer", "orcid": null}, "institutions": [{"id": "https://openalex.org/I129774422", "display_name": "University of Vienna", "ror": "https://ror.org/03prydq77", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I129774422"]}, {"id": "https://openalex.org/I76134821", "display_name": "Medical University of Vienna", "ror": "https://ror.org/05n3x4p02", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I76134821"]}], "countries": ["AT"], "is_corresponding": false, "raw_author_name": "Renate Thalhammer-Scherrer", "raw_affiliation_strings": ["From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria"], "affiliations": [{"raw_affiliation_string": "From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria", "institution_ids": ["https://openalex.org/I129774422", "https://openalex.org/I76134821"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5072208578", "display_name": "Ilse Schwarzinger", "orcid": "https://orcid.org/0000-0001-8250-6520"}, "institutions": [{"id": "https://openalex.org/I129774422", "display_name": "University of Vienna", "ror": "https://ror.org/03prydq77", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I129774422"]}, {"id": "https://openalex.org/I76134821", "display_name": "Medical University of Vienna", "ror": "https://ror.org/05n3x4p02", "country_code": "AT", "type": "education", "lineage": ["https://openalex.org/I76134821"]}], "countries": ["AT"], "is_corresponding": true, "raw_author_name": "Ilse Schwarzinger", "raw_affiliation_strings": ["From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria", "Reprints: Ilse Schwarzinger, MD, Department of Laboratory Medicine, University of Vienna, W\u00e4hringer G\u00fcrtel 18-20, A-1090, Vienna, Austria (ilse.schwarzinger@univie.ac.at)"], "affiliations": [{"raw_affiliation_string": "From the Department of Laboratory Medicine, University of Vienna, Vienna, Austria", "institution_ids": ["https://openalex.org/I129774422", "https://openalex.org/I76134821"]}, {"raw_affiliation_string": "Reprints: Ilse Schwarzinger, MD, Department of Laboratory Medicine, University of Vienna, W\u00e4hringer G\u00fcrtel 18-20, A-1090, Vienna, Austria (ilse.schwarzinger@univie.ac.at)", "institution_ids": ["https://openalex.org/I76134821"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 4, "corresponding_author_ids": ["https://openalex.org/A5072208578"], "corresponding_institution_ids": ["https://openalex.org/I129774422", "https://openalex.org/I76134821"], "apc_list": null, "apc_paid": null, "fwci": 1.8476, "has_fulltext": false, "cited_by_count": 114, "citation_normalized_percentile": {"value": 0.85194589, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 91, "max": 99}, "biblio": {"volume": "125", "issue": "3", "first_page": "391", "last_page": "396"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9972000122070312, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9972000122070312, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T11534", "display_name": "Erythropoietin and Anemia Treatment", "score": 0.9955999851226807, "subfield": {"id": "https://openalex.org/subfields/2720", "display_name": "Hematology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12874", "display_name": "Digital Imaging for Blood Diseases", "score": 0.9929999709129333, "subfield": {"id": "https://openalex.org/subfields/1707", "display_name": "Computer Vision and Pattern Recognition"}, "field": {"id": "https://openalex.org/fields/17", "display_name": "Computer Science"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.893220067024231}, {"id": "https://openalex.org/keywords/flagging", "display_name": "Flagging", "score": 0.7057925462722778}, {"id": "https://openalex.org/keywords/white-blood-cell", "display_name": "White blood cell", "score": 0.694536030292511}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.5837392210960388}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.4424816966056824}, {"id": "https://openalex.org/keywords/blood-cell", "display_name": "Blood cell", "score": 0.42945507168769836}, {"id": "https://openalex.org/keywords/context", "display_name": "Context (archaeology)", "score": 0.4289156198501587}, {"id": "https://openalex.org/keywords/nuclear-medicine", "display_name": "Nuclear medicine", "score": 0.42591580748558044}, {"id": "https://openalex.org/keywords/nucleated-red-blood-cell", "display_name": "Nucleated Red Blood Cell", "score": 0.42357492446899414}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.3775070905685425}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.3060522973537445}, {"id": "https://openalex.org/keywords/biology", "display_name": "Biology", "score": 0.11401382088661194}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.893220067024231}, {"id": "https://openalex.org/C2777548347", "wikidata": "https://www.wikidata.org/wiki/Q5456937", "display_name": "Flagging", "level": 2, "score": 0.7057925462722778}, {"id": "https://openalex.org/C2778488018", "wikidata": "https://www.wikidata.org/wiki/Q42395", "display_name": "White blood cell", "level": 2, "score": 0.694536030292511}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.5837392210960388}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.4424816966056824}, {"id": "https://openalex.org/C2779979121", "wikidata": "https://www.wikidata.org/wiki/Q211709", "display_name": "Blood cell", "level": 2, "score": 0.42945507168769836}, {"id": "https://openalex.org/C2779343474", "wikidata": "https://www.wikidata.org/wiki/Q3109175", "display_name": "Context (archaeology)", "level": 2, "score": 0.4289156198501587}, {"id": "https://openalex.org/C2989005", "wikidata": "https://www.wikidata.org/wiki/Q214963", "display_name": "Nuclear medicine", "level": 1, "score": 0.42591580748558044}, {"id": "https://openalex.org/C2910929737", "wikidata": "https://www.wikidata.org/wiki/Q3296909", "display_name": "Nucleated Red Blood Cell", "level": 4, "score": 0.42357492446899414}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.3775070905685425}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.3060522973537445}, {"id": "https://openalex.org/C86803240", "wikidata": "https://www.wikidata.org/wiki/Q420", "display_name": "Biology", "level": 0, "score": 0.11401382088661194}, {"id": "https://openalex.org/C172680121", "wikidata": "https://www.wikidata.org/wiki/Q26513", "display_name": "Fetus", "level": 3, "score": 0.0}, {"id": "https://openalex.org/C2779234561", "wikidata": "https://www.wikidata.org/wiki/Q11995", "display_name": "Pregnancy", "level": 2, "score": 0.0}, {"id": "https://openalex.org/C151730666", "wikidata": "https://www.wikidata.org/wiki/Q7205", "display_name": "Paleontology", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C95457728", "wikidata": "https://www.wikidata.org/wiki/Q309", "display_name": "History", "level": 0, "score": 0.0}, {"id": "https://openalex.org/C54355233", "wikidata": "https://www.wikidata.org/wiki/Q7162", "display_name": "Genetics", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C166957645", "wikidata": "https://www.wikidata.org/wiki/Q23498", "display_name": "Archaeology", "level": 1, "score": 0.0}], "mesh": [], "locations_count": 1, "locations": [{"id": "doi:10.5858/2001-125-0391-tnhasx", "is_oa": false, "landing_page_url": "https://doi.org/10.5858/2001-125-0391-tnhasx", "pdf_url": null, "source": {"id": "https://openalex.org/S139062638", "display_name": "Archives of Pathology & Laboratory Medicine", "issn_l": "0003-9985", "issn": ["0003-9985", "1543-2165"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320259", "host_organization_name": "American Medical Association", "host_organization_lineage": ["https://openalex.org/P4310320259"], "host_organization_lineage_names": ["American Medical Association"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of Pathology &amp; Laboratory Medicine", "raw_type": "journal-article"}], "best_oa_location": null, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 24, "referenced_works": ["https://openalex.org/W68602231", "https://openalex.org/W1581962345", "https://openalex.org/W1909632531", "https://openalex.org/W1978892637", "https://openalex.org/W1980090876", "https://openalex.org/W2000199207", "https://openalex.org/W2044127972", "https://openalex.org/W2056703613", "https://openalex.org/W2068953235", "https://openalex.org/W2086124279", "https://openalex.org/W2090338522", "https://openalex.org/W2123695478", "https://openalex.org/W2136978454", "https://openalex.org/W2141441177", "https://openalex.org/W2161004488", "https://openalex.org/W2163385433", "https://openalex.org/W2187001514", "https://openalex.org/W2189033549", "https://openalex.org/W2315254983", "https://openalex.org/W2335099826", "https://openalex.org/W4285719527", "https://openalex.org/W6650421745", "https://openalex.org/W6683690826", "https://openalex.org/W6687290189"], "related_works": ["https://openalex.org/W2413287337", "https://openalex.org/W2766026381", "https://openalex.org/W2990742494", "https://openalex.org/W4296136911", "https://openalex.org/W2164536584", "https://openalex.org/W1577078997", "https://openalex.org/W2760843728", "https://openalex.org/W2038529049", "https://openalex.org/W3193987711", "https://openalex.org/W2368144026"], "abstract_inverted_index": {"Abstract": [0], "Context.": [1], "\u2014The": [2], "new": [3, 193], "hematology": [4, 66], "analyzer": [5, 67], "Sysmex": [6, 41, 68, 187], "XE-2100": [7, 42, 101, 201], "(TOA": [8, 70], "Medical": [9, 71], "Electronics,": [10], "Kobe,": [11], "Japan)": [12], "has": [13], "a": [14, 23, 203], "novel,": [15], "combined,": [16], "white": [17, 94, 148, 194, 212], "blood": [18, 31, 77, 95, 149, 165, 195, 213], "cell": [19, 96, 166, 196], "differential": [20, 97, 197], "technology": [21, 198], "and": [22, 54, 57, 84, 113, 120, 123, 128, 134, 154, 161, 179], "special": [24], "reagent": [25], "system": [26], "to": [27, 44], "enumerate": [28], "nucleated": [29, 163], "red": [30, 164], "cells.": [32, 214], "Design.": [33], "\u2014Performance": [34], "evaluation": [35, 178], "of": [36, 39, 48, 59, 87, 140, 145, 159, 186, 199, 210], "both": [37], "technologies": [38], "the": [40, 45, 49, 60, 65, 88, 100, 106, 143, 176, 192, 200], "according": [43], "H20-A": [46], "protocol": [47], "National": [50], "Committee": [51], "for": [52, 64, 110, 126, 142], "Clinical": [53], "Laboratory": [55], "Standards": [56], "comparison": [58], "results": [61], "with": [62, 105, 183], "those": [63], "NE-8000": [69], "Electronics).": [72], "Specimens.": [73], "\u2014Five": [74], "hundred": [75], "forty-four": [76], "samples": [78], "randomly": [79], "chosen": [80], "from": [81], "various": [82], "inpatient": [83], "outpatient": [85], "departments": [86], "Vienna": [89], "University": [90], "hospital.": [91], "Results.": [92], "\u2014Five-part": [93], "counts": [98, 167], "on": [99], "revealed": [102], "excellent": [103, 169], "correlation": [104, 125, 158], "manual": [107], "reference": [108], "method": [109], "neutrophils,": [111], "lymphocytes,": [112], "eosinophils": [114], "(": [115, 130, 170], "r": [116, 131, 171], "=": [117, 132, 172], ".925,": [118], ".922,": [119], ".877,": [121], "respectively)": [122], "good": [124], "monocytes": [127], "basophils": [129], ".756": [133], ".763,": [135], "respectively).": [136], "The": [137, 157], "efficiency": [138], "rates": [139], "flagging": [141, 209], "presence": [144], "\u22651%": [146], "abnormal": [147, 211], "cells": [150], "were": [151], "83%": [152], "(XE-2100)": [153], "66%": [155], "(NE-8000).": [156], "automated": [160], "microscopic": [162], "was": [168], ".97).": [173], "Conclusions.": [174], "\u2014From": [175], "present": [177], "our": [180], "former": [181], "experience": [182], "other": [184], "types": [185], "analyzers,": [188], "we": [189], "conclude": [190], "that": [191], "represents": [202], "further": [204], "development": [205], "toward": [206], "more": [207], "efficient": [208]}, "counts_by_year": [{"year": 2026, "cited_by_count": 2}, {"year": 2025, "cited_by_count": 1}, {"year": 2024, "cited_by_count": 2}, {"year": 2023, "cited_by_count": 5}, {"year": 2022, "cited_by_count": 4}, {"year": 2021, "cited_by_count": 4}, {"year": 2020, "cited_by_count": 4}, {"year": 2019, "cited_by_count": 5}, {"year": 2018, "cited_by_count": 3}, {"year": 2017, "cited_by_count": 4}, {"year": 2016, "cited_by_count": 6}, {"year": 2015, "cited_by_count": 3}, {"year": 2014, "cited_by_count": 12}, {"year": 2013, "cited_by_count": 7}, {"year": 2012, "cited_by_count": 7}], "updated_date": "2026-04-14T08:04:32.555800", "created_date": "2016-06-24T00:00:00"}, {"id": "https://openalex.org/W4288249862", "doi": "https://doi.org/10.5281/zenodo.3379727", "title": "Hematology Analyzers and Reagents Market by Products and Services, Price Range &amp; End User - 2023", "display_name": "Hematology Analyzers and Reagents Market by Products and Services, Price Range &amp; End User - 2023", "relevance_score": 67.63643, "publication_year": 2019, "publication_date": "2019-08-28", "ids": {"openalex": "https://openalex.org/W4288249862", "doi": "https://doi.org/10.5281/zenodo.3379727"}, "language": "en", "primary_location": {"id": "pmh:oai:zenodo.org:3379727", "is_oa": true, "landing_page_url": "https://zenodo.org/record/3379727", "pdf_url": null, "source": {"id": "https://openalex.org/S4306400562", "display_name": "Zenodo (CERN European Organization for Nuclear Research)", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I67311998", "host_organization_name": "European Organization for Nuclear Research", "host_organization_lineage": ["https://openalex.org/I67311998"], "host_organization_lineage_names": [], "type": "repository"}, "license": "other-oa", "license_id": "https://openalex.org/licenses/other-oa", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "", "raw_type": "info:eu-repo/semantics/article"}, "type": "article", "indexed_in": [], "open_access": {"is_oa": true, "oa_status": "green", "oa_url": "https://zenodo.org/record/3379727", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": null, "display_name": "snehalshaha", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": true, "raw_author_name": "snehalshaha", "raw_affiliation_strings": [], "raw_orcid": null, "affiliations": []}], "institutions": [], "countries_distinct_count": 0, "institutions_distinct_count": 1, "corresponding_author_ids": [], "corresponding_institution_ids": [], "apc_list": null, "apc_paid": null, "fwci": 0.0, "has_fulltext": false, "cited_by_count": 0, "citation_normalized_percentile": {"value": 0.62705208, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": null, "biblio": {"volume": null, "issue": null, "first_page": null, "last_page": null}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T13497", "display_name": "Hermeneutics and Narrative Identity", "score": 0.9879000186920166, "subfield": {"id": "https://openalex.org/subfields/1211", "display_name": "Philosophy"}, "field": {"id": "https://openalex.org/fields/12", "display_name": "Arts and Humanities"}, "domain": {"id": "https://openalex.org/domains/2", "display_name": "Social Sciences"}}, "topics": [{"id": "https://openalex.org/T13497", "display_name": "Hermeneutics and Narrative Identity", "score": 0.9879000186920166, "subfield": {"id": "https://openalex.org/subfields/1211", "display_name": "Philosophy"}, "field": {"id": "https://openalex.org/fields/12", "display_name": "Arts and Humanities"}, "domain": {"id": "https://openalex.org/domains/2", "display_name": "Social Sciences"}}, {"id": "https://openalex.org/T13695", "display_name": "Aging, Elder Care, and Social Issues", "score": 0.9749000072479248, "subfield": {"id": "https://openalex.org/subfields/3600", "display_name": "General Health Professions"}, "field": {"id": "https://openalex.org/fields/36", "display_name": "Health Professions"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T13099", "display_name": "Health, Medicine and Society", "score": 0.95660001039505, "subfield": {"id": "https://openalex.org/subfields/3600", "display_name": "General Health Professions"}, "field": {"id": "https://openalex.org/fields/36", "display_name": "Health Professions"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.5934854745864868}, {"id": "https://openalex.org/keywords/range", "display_name": "Range (aeronautics)", "score": 0.527216911315918}, {"id": "https://openalex.org/keywords/end-user", "display_name": "End user", "score": 0.5073422789573669}, {"id": "https://openalex.org/keywords/business", "display_name": "Business", "score": 0.4203265309333801}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.3628805875778198}, {"id": "https://openalex.org/keywords/world-wide-web", "display_name": "World Wide Web", "score": 0.2738974690437317}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.22341197729110718}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.2109476625919342}, {"id": "https://openalex.org/keywords/engineering", "display_name": "Engineering", "score": 0.1995566487312317}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.5934854745864868}, {"id": "https://openalex.org/C204323151", "wikidata": "https://www.wikidata.org/wiki/Q905424", "display_name": "Range (aeronautics)", "level": 2, "score": 0.527216911315918}, {"id": "https://openalex.org/C91262260", "wikidata": "https://www.wikidata.org/wiki/Q528074", "display_name": "End user", "level": 2, "score": 0.5073422789573669}, {"id": "https://openalex.org/C144133560", "wikidata": "https://www.wikidata.org/wiki/Q4830453", "display_name": "Business", "level": 0, "score": 0.4203265309333801}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.3628805875778198}, {"id": "https://openalex.org/C136764020", "wikidata": "https://www.wikidata.org/wiki/Q466", "display_name": "World Wide Web", "level": 1, "score": 0.2738974690437317}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.22341197729110718}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.2109476625919342}, {"id": "https://openalex.org/C127413603", "wikidata": "https://www.wikidata.org/wiki/Q11023", "display_name": "Engineering", "level": 0, "score": 0.1995566487312317}, {"id": "https://openalex.org/C146978453", "wikidata": "https://www.wikidata.org/wiki/Q3798668", "display_name": "Aerospace engineering", "level": 1, "score": 0.0}], "mesh": [], "locations_count": 1, "locations": [{"id": "pmh:oai:zenodo.org:3379727", "is_oa": true, "landing_page_url": "https://zenodo.org/record/3379727", "pdf_url": null, "source": {"id": "https://openalex.org/S4306400562", "display_name": "Zenodo (CERN European Organization for Nuclear Research)", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I67311998", "host_organization_name": "European Organization for Nuclear Research", "host_organization_lineage": ["https://openalex.org/I67311998"], "host_organization_lineage_names": [], "type": "repository"}, "license": "other-oa", "license_id": "https://openalex.org/licenses/other-oa", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "", "raw_type": "info:eu-repo/semantics/article"}], "best_oa_location": {"id": "pmh:oai:zenodo.org:3379727", "is_oa": true, "landing_page_url": "https://zenodo.org/record/3379727", "pdf_url": null, "source": {"id": "https://openalex.org/S4306400562", "display_name": "Zenodo (CERN European Organization for Nuclear Research)", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I67311998", "host_organization_name": "European Organization for Nuclear Research", "host_organization_lineage": ["https://openalex.org/I67311998"], "host_organization_lineage_names": [], "type": "repository"}, "license": "other-oa", "license_id": "https://openalex.org/licenses/other-oa", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "", "raw_type": "info:eu-repo/semantics/article"}, "sustainable_development_goals": [{"display_name": "Industry, innovation and infrastructure", "id": "https://metadata.un.org/sdg/9", "score": 0.4099999964237213}], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 0, "referenced_works": [], "related_works": ["https://openalex.org/W2899084033", "https://openalex.org/W2748952813", "https://openalex.org/W2376685908", "https://openalex.org/W2385252980", "https://openalex.org/W2352668361", "https://openalex.org/W2361853464", "https://openalex.org/W1601719760", "https://openalex.org/W2352314160", "https://openalex.org/W2394278344", "https://openalex.org/W2375693729"], "abstract_inverted_index": {"The": [0], "Hematology": [1], "Analyzers": [2], "and": [3], "Reagents": [4], "Market": [5], "is": [6], "projected": [7], "to": [8], "reach": [9], "USD": [10, 16], "5.0": [11], "billion": [12, 18], "by": [13], "2023": [14], "from": [15], "3.3": [17], "in": [19], "2018,": [20], "at": [21], "a": [22], "CAGR": [23], "of": [24], "8.5%": [25], "during": [26], "the": [27], "forecast": [28], "period.": [29]}, "counts_by_year": [], "updated_date": "2026-04-28T14:05:53.105641", "created_date": "2022-07-28T00:00:00"}, {"id": "https://openalex.org/W2119703741", "doi": "https://doi.org/10.1309/l7lc-6kkj-12g2-196w", "title": "Evaluation of the Abbott CELL-DYN 4000 Hematology Analyzer", "display_name": "Evaluation of the Abbott CELL-DYN 4000 Hematology Analyzer", "relevance_score": 66.98562, "publication_year": 2000, "publication_date": "2000-04-01", "ids": {"openalex": "https://openalex.org/W2119703741", "doi": "https://doi.org/10.1309/l7lc-6kkj-12g2-196w", "mag": "2119703741", "pmid": "https://pubmed.ncbi.nlm.nih.gov/10761450"}, "language": "en", "primary_location": {"id": "doi:10.1309/l7lc-6kkj-12g2-196w", "is_oa": true, "landing_page_url": "https://doi.org/10.1309/l7lc-6kkj-12g2-196w", "pdf_url": "https://academic.oup.com/ajcp/article-pdf/113/4/497/24980478/ajcpath113-0497.pdf", "source": {"id": "https://openalex.org/S15871148", "display_name": "American Journal of Clinical Pathology", "issn_l": "0002-9173", "issn": ["0002-9173", "1943-7722"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310311648", "host_organization_name": "Oxford University Press", "host_organization_lineage": ["https://openalex.org/P4310311648", "https://openalex.org/P4310311647"], "host_organization_lineage_names": ["Oxford University Press", "University of Oxford"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Clinical Pathology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "bronze", "oa_url": "https://academic.oup.com/ajcp/article-pdf/113/4/497/24980478/ajcpath113-0497.pdf", "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5108419539", "display_name": "Ernesto Grimaldi", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": true, "raw_author_name": "Ernesto Grimaldi", "raw_affiliation_strings": ["Department of Laboratory Medicine, Universit\u00e0 Federico II, Naples, Italy"], "affiliations": [{"raw_affiliation_string": "Department of Laboratory Medicine, Universit\u00e0 Federico II, Naples, Italy", "institution_ids": []}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5111377313", "display_name": "Francesco Scopacasa", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Francesco Scopacasa", "raw_affiliation_strings": ["Department of Laboratory Medicine, Universit\u00e0 Federico II, Naples, Italy"], "affiliations": [{"raw_affiliation_string": "Department of Laboratory Medicine, Universit\u00e0 Federico II, Naples, Italy", "institution_ids": []}]}], "institutions": [], "countries_distinct_count": 0, "institutions_distinct_count": 2, "corresponding_author_ids": ["https://openalex.org/A5108419539"], "corresponding_institution_ids": [], "apc_list": {"value": 4440, "currency": "USD", "value_usd": 4440}, "apc_paid": null, "fwci": 1.5614, "has_fulltext": true, "cited_by_count": 60, "citation_normalized_percentile": {"value": 0.82551207, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 99}, "biblio": {"volume": "113", "issue": "4", "first_page": "497", "last_page": "505"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9995999932289124, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9995999932289124, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.9922999739646912, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T10554", "display_name": "Hemoglobinopathies and Related Disorders", "score": 0.9815999865531921, "subfield": {"id": "https://openalex.org/subfields/2716", "display_name": "Genetics"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/autoanalyzer", "display_name": "AutoAnalyzer", "score": 0.9057731628417969}, {"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.8410905599594116}, {"id": "https://openalex.org/keywords/spectrum-analyzer", "display_name": "Spectrum analyzer", "score": 0.5460827350616455}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.5046473741531372}, {"id": "https://openalex.org/keywords/basophil", "display_name": "Basophil", "score": 0.4478576183319092}, {"id": "https://openalex.org/keywords/correlation-coefficient", "display_name": "Correlation coefficient", "score": 0.43199437856674194}, {"id": "https://openalex.org/keywords/immunology", "display_name": "Immunology", "score": 0.402595579624176}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.33056092262268066}, {"id": "https://openalex.org/keywords/mathematics", "display_name": "Mathematics", "score": 0.19059231877326965}, {"id": "https://openalex.org/keywords/statistics", "display_name": "Statistics", "score": 0.1030978262424469}, {"id": "https://openalex.org/keywords/antibody", "display_name": "Antibody", "score": 0.09768787026405334}, {"id": "https://openalex.org/keywords/physics", "display_name": "Physics", "score": 0.084816575050354}], "concepts": [{"id": "https://openalex.org/C170094789", "wikidata": "https://www.wikidata.org/wiki/Q4826058", "display_name": "AutoAnalyzer", "level": 2, "score": 0.9057731628417969}, {"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.8410905599594116}, {"id": "https://openalex.org/C158007255", "wikidata": "https://www.wikidata.org/wiki/Q1055222", "display_name": "Spectrum analyzer", "level": 2, "score": 0.5460827350616455}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.5046473741531372}, {"id": "https://openalex.org/C2777456892", "wikidata": "https://www.wikidata.org/wiki/Q107988", "display_name": "Basophil", "level": 4, "score": 0.4478576183319092}, {"id": "https://openalex.org/C2780092901", "wikidata": "https://www.wikidata.org/wiki/Q3433612", "display_name": "Correlation coefficient", "level": 2, "score": 0.43199437856674194}, {"id": "https://openalex.org/C203014093", "wikidata": "https://www.wikidata.org/wiki/Q101929", "display_name": "Immunology", "level": 1, "score": 0.402595579624176}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.33056092262268066}, {"id": "https://openalex.org/C33923547", "wikidata": "https://www.wikidata.org/wiki/Q395", "display_name": "Mathematics", "level": 0, "score": 0.19059231877326965}, {"id": "https://openalex.org/C105795698", "wikidata": "https://www.wikidata.org/wiki/Q12483", "display_name": "Statistics", "level": 1, "score": 0.1030978262424469}, {"id": "https://openalex.org/C159654299", "wikidata": "https://www.wikidata.org/wiki/Q79460", "display_name": "Antibody", "level": 2, "score": 0.09768787026405334}, {"id": "https://openalex.org/C121332964", "wikidata": "https://www.wikidata.org/wiki/Q413", "display_name": "Physics", "level": 0, "score": 0.084816575050354}, {"id": "https://openalex.org/C120665830", "wikidata": "https://www.wikidata.org/wiki/Q14620", "display_name": "Optics", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C141105273", "wikidata": "https://www.wikidata.org/wiki/Q79455", "display_name": "Immunoglobulin E", "level": 3, "score": 0.0}], "mesh": [{"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": true}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": true}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": true}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006405", "descriptor_name": "Hematology", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008055", "descriptor_name": "Lipids", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D008055", "descriptor_name": "Lipids", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D008055", "descriptor_name": "Lipids", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D013048", "descriptor_name": "Specimen Handling", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013048", "descriptor_name": "Specimen Handling", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013048", "descriptor_name": "Specimen Handling", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "doi:10.1309/l7lc-6kkj-12g2-196w", "is_oa": true, "landing_page_url": "https://doi.org/10.1309/l7lc-6kkj-12g2-196w", "pdf_url": "https://academic.oup.com/ajcp/article-pdf/113/4/497/24980478/ajcpath113-0497.pdf", "source": {"id": "https://openalex.org/S15871148", "display_name": "American Journal of Clinical Pathology", "issn_l": "0002-9173", "issn": ["0002-9173", "1943-7722"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310311648", "host_organization_name": "Oxford University Press", "host_organization_lineage": ["https://openalex.org/P4310311648", "https://openalex.org/P4310311647"], "host_organization_lineage_names": ["Oxford University Press", "University of Oxford"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Clinical Pathology", "raw_type": "journal-article"}, {"id": "pmid:10761450", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/10761450", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American journal of clinical pathology", "raw_type": null}], "best_oa_location": {"id": "doi:10.1309/l7lc-6kkj-12g2-196w", "is_oa": true, "landing_page_url": "https://doi.org/10.1309/l7lc-6kkj-12g2-196w", "pdf_url": "https://academic.oup.com/ajcp/article-pdf/113/4/497/24980478/ajcpath113-0497.pdf", "source": {"id": "https://openalex.org/S15871148", "display_name": "American Journal of Clinical Pathology", "issn_l": "0002-9173", "issn": ["0002-9173", "1943-7722"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310311648", "host_organization_name": "Oxford University Press", "host_organization_lineage": ["https://openalex.org/P4310311648", "https://openalex.org/P4310311647"], "host_organization_lineage_names": ["Oxford University Press", "University of Oxford"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Clinical Pathology", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W2119703741.pdf"}, "referenced_works_count": 6, "referenced_works": ["https://openalex.org/W1525176287", "https://openalex.org/W1581962345", "https://openalex.org/W1978892637", "https://openalex.org/W2076825662", "https://openalex.org/W2157278699", "https://openalex.org/W4285719527"], "related_works": ["https://openalex.org/W2314366310", "https://openalex.org/W182924711", "https://openalex.org/W2323282862", "https://openalex.org/W2398349691", "https://openalex.org/W1640955489", "https://openalex.org/W2418177264", "https://openalex.org/W2409512531", "https://openalex.org/W2367382573", "https://openalex.org/W2400252220", "https://openalex.org/W2364386882"], "abstract_inverted_index": {"A": [0, 57], "new": [1, 161], "generation": [2], "hematology": [3], "analyzer,": [4, 49], "Abbott": [5, 162], "CELL-DYN": [6], "4000": [7], "(CD": [8], "4000),": [9], "capable": [10], "of": [11, 92, 130, 138], "providing": [12], "26": [13], "parameters,": [14], "including": [15], "fully": [16], "automated": [17], "reticulocyte,": [18], "nucleated": [19], "RBC,": [20], "blast,": [21], "band,": [22], "and": [23, 26, 43, 61, 71, 81, 107, 114, 116, 171, 176], "immature": [24], "granulocyte,": [25], "variant": [27], "lymphocyte": [28], "counts,": [29], "was": [30, 84, 150, 167], "evaluated": [31], "by": [32, 78, 158], "using": [33, 159], "the": [34, 46, 75, 79, 87, 101, 139, 143, 154, 165], "National": [35], "Committee": [36], "for": [37, 105, 112, 120, 127], "Clinical": [38], "Laboratory": [39], "Standards": [40], "H20-A": [41], "protocol": [42], "compared": [44], "with": [45, 86, 100, 124], "Bayer-Technicon": [47], "H-2": [48, 88], "which": [50], "is": [51], "used": [52], "routinely": [53], "in": [54, 122], "our": [55], "laboratory.": [56], "lipid": [58, 144], "interference": [59, 145, 166], "experiment": [60], "a": [62, 109, 117, 160, 190], "sample": [63], "aging": [64], "study": [65], "also": [66], "were": [67, 73, 174], "performed.": [68], "Linearity,": [69], "carryover,": [70], "precision": [72], "within": [74], "limits": [76], "established": [77], "manufacturer,": [80], "satisfactory": [82], "agreement": [83], "found": [85, 135], "analyzer.": [89], "The": [90, 169], "evaluation": [91], "leukocyte": [93], "differential": [94, 172], "counts": [95, 129, 173], "indicated": [96], "an": [97, 136], "excellent": [98], "correlation": [99, 111, 119, 140], "manual": [102], "reference": [103], "method": [104], "neutrophils": [106], "lymphocytes,": [108], "good": [110], "monocytes": [113], "eosinophils,": [115], "poor": [118], "basophils": [121], "samples": [123], "low": [125], "counts;": [126], "basophil": [128], "2%": [131], "or": [132], "higher,": [133], "we": [134], "improvement": [137], "coefficient.": [141], "In": [142], "experiment,": [146], "only": [147], "hemoglobin": [148, 163], "determination": [149], "influenced": [151], "significantly": [152], "on": [153, 187, 193], "CD": [155], "4000,": [156], "but": [157], "reagent,": [164], "eliminated.": [168], "CBC": [170], "stable": [175], "reportable": [177], "up": [178], "to": [179], "at": [180], "least": [181], "24": [182], "hours.": [183], "Intrasample": [184], "viability": [185], "information": [186], "leukocytes": [188], "provided": [189], "quality": [191], "check": [192], "each": [194], "individual": [195], "specimen.": [196]}, "counts_by_year": [{"year": 2025, "cited_by_count": 2}, {"year": 2023, "cited_by_count": 1}, {"year": 2022, "cited_by_count": 1}, {"year": 2021, "cited_by_count": 1}, {"year": 2019, "cited_by_count": 2}, {"year": 2018, "cited_by_count": 2}, {"year": 2017, "cited_by_count": 1}, {"year": 2016, "cited_by_count": 2}, {"year": 2015, "cited_by_count": 3}, {"year": 2014, "cited_by_count": 6}, {"year": 2013, "cited_by_count": 1}, {"year": 2012, "cited_by_count": 1}], "updated_date": "2026-01-15T23:16:33.117629", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W1969811847", "doi": "https://doi.org/10.1002/jcla.10103", "title": "Comparison between the enzymatic vitros assay for creatinine determination and three other methods adapted on the olympus analyzer", "display_name": "Comparison between the enzymatic vitros assay for creatinine determination and three other methods adapted on the olympus analyzer", "relevance_score": 66.29579, "publication_year": 2003, "publication_date": "2003-01-01", "ids": {"openalex": "https://openalex.org/W1969811847", "doi": "https://doi.org/10.1002/jcla.10103", "mag": "1969811847", "pmid": "https://pubmed.ncbi.nlm.nih.gov/14614747"}, "language": "en", "primary_location": {"id": "doi:10.1002/jcla.10103", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/jcla.10103", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcla.10103", "source": {"id": "https://openalex.org/S28295008", "display_name": "Journal of Clinical Laboratory Analysis", "issn_l": "0887-8013", "issn": ["0887-8013", "1098-2825"], "is_oa": false, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Journal of Clinical Laboratory Analysis", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "doaj", "pubmed"], "open_access": {"is_oa": true, "oa_status": "bronze", "oa_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcla.10103", "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5068463559", "display_name": "St\u00e9phanie Badiou", "orcid": "https://orcid.org/0000-0001-6128-8114"}, "institutions": [{"id": "https://openalex.org/I4210132125", "display_name": "H\u00f4pital Lapeyronie", "ror": "https://ror.org/03xzagw65", "country_code": "FR", "type": "healthcare", "lineage": ["https://openalex.org/I4210093292", "https://openalex.org/I4210132125"]}], "countries": ["FR"], "is_corresponding": false, "raw_author_name": "S. Badiou", "raw_affiliation_strings": ["Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France"], "affiliations": [{"raw_affiliation_string": "Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France", "institution_ids": ["https://openalex.org/I4210132125"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5033608809", "display_name": "Anne\u2010Marie Dupuy", "orcid": "https://orcid.org/0000-0001-6538-3944"}, "institutions": [{"id": "https://openalex.org/I4210132125", "display_name": "H\u00f4pital Lapeyronie", "ror": "https://ror.org/03xzagw65", "country_code": "FR", "type": "healthcare", "lineage": ["https://openalex.org/I4210093292", "https://openalex.org/I4210132125"]}], "countries": ["FR"], "is_corresponding": false, "raw_author_name": "A.M. Dupuy", "raw_affiliation_strings": ["Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France"], "affiliations": [{"raw_affiliation_string": "Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France", "institution_ids": ["https://openalex.org/I4210132125"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5112202753", "display_name": "B. Descomps", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210132125", "display_name": "H\u00f4pital Lapeyronie", "ror": "https://ror.org/03xzagw65", "country_code": "FR", "type": "healthcare", "lineage": ["https://openalex.org/I4210093292", "https://openalex.org/I4210132125"]}], "countries": ["FR"], "is_corresponding": false, "raw_author_name": "B. Descomps", "raw_affiliation_strings": ["Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France"], "affiliations": [{"raw_affiliation_string": "Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France", "institution_ids": ["https://openalex.org/I4210132125"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5089097108", "display_name": "J.P. Cristolead", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210132125", "display_name": "H\u00f4pital Lapeyronie", "ror": "https://ror.org/03xzagw65", "country_code": "FR", "type": "healthcare", "lineage": ["https://openalex.org/I4210093292", "https://openalex.org/I4210132125"]}], "countries": ["FR"], "is_corresponding": true, "raw_author_name": "J.P. Cristolead", "raw_affiliation_strings": ["Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France"], "affiliations": [{"raw_affiliation_string": "Laboratoire de Biochimie, Hopital Lapeyronie, Montpellier, France", "institution_ids": ["https://openalex.org/I4210132125"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 4, "corresponding_author_ids": ["https://openalex.org/A5089097108"], "corresponding_institution_ids": ["https://openalex.org/I4210132125"], "apc_list": {"value": 3850, "currency": "USD", "value_usd": 3850}, "apc_paid": null, "fwci": 0.4816, "has_fulltext": true, "cited_by_count": 49, "citation_normalized_percentile": {"value": 0.62864713, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 98}, "biblio": {"volume": "17", "issue": "6", "first_page": "235", "last_page": "240"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9975000023841858, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9975000023841858, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T10408", "display_name": "Chronic Kidney Disease and Diabetes", "score": 0.9944000244140625, "subfield": {"id": "https://openalex.org/subfields/2727", "display_name": "Nephrology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T11534", "display_name": "Erythropoietin and Anemia Treatment", "score": 0.9937999844551086, "subfield": {"id": "https://openalex.org/subfields/2720", "display_name": "Hematology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/creatinine", "display_name": "Creatinine", "score": 0.9237840175628662}, {"id": "https://openalex.org/keywords/spectrum-analyzer", "display_name": "Spectrum analyzer", "score": 0.6189426183700562}, {"id": "https://openalex.org/keywords/chromatography", "display_name": "Chromatography", "score": 0.5516100525856018}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.4922391474246979}, {"id": "https://openalex.org/keywords/bilirubin", "display_name": "Bilirubin", "score": 0.4667409062385559}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.4343584179878235}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.28703635931015015}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.06208091974258423}], "concepts": [{"id": "https://openalex.org/C2780306776", "wikidata": "https://www.wikidata.org/wiki/Q426660", "display_name": "Creatinine", "level": 2, "score": 0.9237840175628662}, {"id": "https://openalex.org/C158007255", "wikidata": "https://www.wikidata.org/wiki/Q1055222", "display_name": "Spectrum analyzer", "level": 2, "score": 0.6189426183700562}, {"id": "https://openalex.org/C43617362", "wikidata": "https://www.wikidata.org/wiki/Q170050", "display_name": "Chromatography", "level": 1, "score": 0.5516100525856018}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.4922391474246979}, {"id": "https://openalex.org/C2777513400", "wikidata": "https://www.wikidata.org/wiki/Q104219", "display_name": "Bilirubin", "level": 2, "score": 0.4667409062385559}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.4343584179878235}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.28703635931015015}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.06208091974258423}, {"id": "https://openalex.org/C76155785", "wikidata": "https://www.wikidata.org/wiki/Q418", "display_name": "Telecommunications", "level": 1, "score": 0.0}], "mesh": [{"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D001322", "descriptor_name": "Autoanalysis", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D003404", "descriptor_name": "Creatinine", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D003404", "descriptor_name": "Creatinine", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D003404", "descriptor_name": "Creatinine", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D003404", "descriptor_name": "Creatinine", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D004796", "descriptor_name": "Clinical Enzyme Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": true}, {"descriptor_ui": "D004796", "descriptor_name": "Clinical Enzyme Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": true}, {"descriptor_ui": "D004796", "descriptor_name": "Clinical Enzyme Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": true}, {"descriptor_ui": "D004796", "descriptor_name": "Clinical Enzyme Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": true}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015203", "descriptor_name": "Reproducibility of Results", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 3, "locations": [{"id": "doi:10.1002/jcla.10103", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/jcla.10103", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcla.10103", "source": {"id": "https://openalex.org/S28295008", "display_name": "Journal of Clinical Laboratory Analysis", "issn_l": "0887-8013", "issn": ["0887-8013", "1098-2825"], "is_oa": false, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Journal of Clinical Laboratory Analysis", "raw_type": "journal-article"}, {"id": "pmid:14614747", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/14614747", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Journal of clinical laboratory analysis", "raw_type": null}, {"id": "pmh:oai:europepmc.org:5805920", "is_oa": false, "landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/6807945", "pdf_url": null, "source": {"id": "https://openalex.org/S4306400806", "display_name": "Europe PMC (PubMed Central)", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1303153112", "host_organization_name": "European Bioinformatics Institute", "host_organization_lineage": ["https://openalex.org/I1303153112"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": null, "raw_type": "Text"}], "best_oa_location": {"id": "doi:10.1002/jcla.10103", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/jcla.10103", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcla.10103", "source": {"id": "https://openalex.org/S28295008", "display_name": "Journal of Clinical Laboratory Analysis", "issn_l": "0887-8013", "issn": ["0887-8013", "1098-2825"], "is_oa": false, "is_in_doaj": true, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Journal of Clinical Laboratory Analysis", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W1969811847.pdf", "grobid_xml": "https://content.openalex.org/works/W1969811847.grobid-xml"}, "referenced_works_count": 7, "referenced_works": ["https://openalex.org/W38278793", "https://openalex.org/W2051628163", "https://openalex.org/W2104808416", "https://openalex.org/W2141348928", "https://openalex.org/W2406764311", "https://openalex.org/W2416615219", "https://openalex.org/W2514425309"], "related_works": ["https://openalex.org/W4387497383", "https://openalex.org/W2948807893", "https://openalex.org/W2778153218", "https://openalex.org/W2748952813", "https://openalex.org/W1531601525", "https://openalex.org/W2078814861", "https://openalex.org/W2394704188", "https://openalex.org/W1893687276", "https://openalex.org/W3133868307", "https://openalex.org/W56616876"], "abstract_inverted_index": {"To": [0], "evaluate": [1], "the": [2, 5, 30, 42, 54, 117, 133, 147, 160], "relationship": [3], "between": [4], "enzymatic": [6, 60, 78, 104], "Vitros": [7, 31], "assay": [8], "for": [9, 100, 116, 123, 140, 152, 174], "creatinine": [10, 17, 24, 82, 137, 156], "determination": [11, 154], "and": [12, 40, 58, 68, 77, 126, 132], "other": [13], "methods,": [14], "we": [15], "determined": [16, 28], "concentration": [18], "in": [19, 53], "400": [20], "heparin": [21], "samples.": [22], "Plasma": [23], "level": [25], "was": [26, 150], "successively": [27], "on": [29, 41, 146], "750": [32], "analyzer": [33, 45], "(Johnson": [34], "&": [35], "Johnson": [36], "Co.,": [37], "Rochester,": [38], "NY)": [39], "Olympus": [43, 148], "AU2700": [44], "(Olympus": [46], "France,": [47], "Rungis,": [48], "France),": [49], "using": [50], "three": [51], "reagents": [52, 105], "same": [55], "assay:": [56], "Olympus-Jaff\u00e9": [57], "two": [59], "commercial": [61], "kits-Crea": [62], "Plus": [63], "(Roche": [64], "Diagnostics,": [65], "Meylan,": [66], "France)": [67], "Enzymatic": [69, 109, 175], "Creatinine": [70, 176], "(Randox,": [71], "Mauguio,": [72], "France).": [73], "Comparison": [74], "of": [75, 80, 120, 135, 155], "Jaff\u00e9": [76], "measurements": [79], "plasma": [81], "levels": [83], "revealed": [84], "a": [85, 112], "high": [86], "correlation": [87], "when": [88], "considering": [89], "all": [90], "values": [91, 101], "ranged": [92], "from": [93], "20-1000": [94], "micromol/l": [95], "(r": [96], ">": [97], "0.99).": [98], "However,": [99], "<60": [102], "micromol/l,": [103], "provided": [106], "best": [107], "results.": [108], "methodology": [110], "is": [111], "better": [113], "clinical": [114], "choice": [115], "accurate": [118], "measurement": [119], "creatinine,": [121], "especially": [122], "neonates,": [124], "pediatrics,": [125], "hematology": [127], "units.": [128], "Because": [129], "analytical": [130], "performance": [131], "costs": [134], "Randox": [136], "were": [138, 172], "satisfactory": [139], "our": [141], "laboratory,": [142], "this": [143], "method,": [144], "adapted": [145], "analyzer,": [149], "chosen": [151], "routine": [153], "levels.": [157], "According": [158], "to": [159], "Valtec": [161], "protocol": [162], "(8),": [163], "no": [164], "interferences": [165], "such": [166], "as": [167], "hemolysis,": [168], "lipemia,": [169], "or": [170], "bilirubin": [171], "detected": [173], "Randox.": [177]}, "counts_by_year": [{"year": 2025, "cited_by_count": 1}, {"year": 2024, "cited_by_count": 1}, {"year": 2023, "cited_by_count": 3}, {"year": 2022, "cited_by_count": 1}, {"year": 2021, "cited_by_count": 5}, {"year": 2020, "cited_by_count": 4}, {"year": 2019, "cited_by_count": 3}, {"year": 2018, "cited_by_count": 2}, {"year": 2017, "cited_by_count": 1}, {"year": 2015, "cited_by_count": 2}, {"year": 2014, "cited_by_count": 3}, {"year": 2013, "cited_by_count": 1}, {"year": 2012, "cited_by_count": 4}], "updated_date": "2026-03-07T16:01:11.037858", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W3016764831", "doi": "https://doi.org/10.1111/ijlh.13230", "title": "Thromboembolic events and apparent heparin resistance in patients infected with SARS\u2010CoV\u20102", "display_name": "Thromboembolic events and apparent heparin resistance in patients infected with SARS\u2010CoV\u20102", "relevance_score": 60.29286, "publication_year": 2020, "publication_date": "2020-04-20", "ids": {"openalex": "https://openalex.org/W3016764831", "doi": "https://doi.org/10.1111/ijlh.13230", "mag": "3016764831", "pmid": "https://pubmed.ncbi.nlm.nih.gov/32311843"}, "language": "en", "primary_location": {"id": "doi:10.1111/ijlh.13230", "is_oa": true, "landing_page_url": "https://doi.org/10.1111/ijlh.13230", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13230", "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "hybrid", "oa_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13230", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5079712124", "display_name": "Robert Beun", "orcid": null}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Robert Beun", "raw_affiliation_strings": ["Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5077627178", "display_name": "Nuray Ku\u015fadasi", "orcid": "https://orcid.org/0000-0003-3504-0996"}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Nuray Kusadasi", "raw_affiliation_strings": ["Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5060537433", "display_name": "Maaike A. Sikma", "orcid": "https://orcid.org/0000-0003-3872-5771"}, "institutions": [{"id": "https://openalex.org/I193662353", "display_name": "Utrecht University", "ror": "https://ror.org/04pp8hn57", "country_code": "NL", "type": "education", "lineage": ["https://openalex.org/I193662353"]}, {"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Maaike Sikma", "raw_affiliation_strings": ["Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "Dutch Poisons Information Center University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "Dutch Poisons Information Center, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands", "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands"], "raw_orcid": "https://orcid.org/0000-0003-3872-5771", "affiliations": [{"raw_affiliation_string": "Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Dutch Poisons Information Center University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "institution_ids": ["https://openalex.org/I3018483916", "https://openalex.org/I193662353"]}, {"raw_affiliation_string": "Dutch Poisons Information Center, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5032480026", "display_name": "Jan Westerink", "orcid": "https://orcid.org/0000-0001-5021-5227"}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Jan Westerink", "raw_affiliation_strings": ["Department of Vascular Medicine University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "Department of Vascular Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Vascular Medicine University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Vascular Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5012927400", "display_name": "Albert Huisman", "orcid": "https://orcid.org/0000-0002-2291-2487"}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": true, "raw_author_name": "Albert Huisman", "raw_affiliation_strings": ["Department of Clinical Chemistry and Laboratory Medicine University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "Department of Clinical Chemistry and Laboratory Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands"], "raw_orcid": "https://orcid.org/0000-0002-2291-2487", "affiliations": [{"raw_affiliation_string": "Department of Clinical Chemistry and Laboratory Medicine University Medical Center Utrecht and University Utrecht Utrecht the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Clinical Chemistry and Laboratory Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, the Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 5, "corresponding_author_ids": ["https://openalex.org/A5012927400"], "corresponding_institution_ids": ["https://openalex.org/I3018483916"], "apc_list": {"value": 3550, "currency": "USD", "value_usd": 3550}, "apc_paid": {"value": 3550, "currency": "USD", "value_usd": 3550}, "fwci": 3.9362, "has_fulltext": false, "cited_by_count": 168, "citation_normalized_percentile": {"value": 0.95964475, "is_in_top_1_percent": false, "is_in_top_10_percent": true}, "cited_by_percentile_year": {"min": 98, "max": 100}, "biblio": {"volume": "42", "issue": "S1", "first_page": "19", "last_page": "20"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T10041", "display_name": "COVID-19 Clinical Research Studies", "score": 0.9998999834060669, "subfield": {"id": "https://openalex.org/subfields/2725", "display_name": "Infectious Diseases"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T10041", "display_name": "COVID-19 Clinical Research Studies", "score": 0.9998999834060669, "subfield": {"id": "https://openalex.org/subfields/2725", "display_name": "Infectious Diseases"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T11296", "display_name": "COVID-19 and healthcare impacts", "score": 0.9979000091552734, "subfield": {"id": "https://openalex.org/subfields/2730", "display_name": "Oncology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T11368", "display_name": "Long-Term Effects of COVID-19", "score": 0.9932000041007996, "subfield": {"id": "https://openalex.org/subfields/2728", "display_name": "Neurology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/heparin", "display_name": "Heparin", "score": 0.756711483001709}, {"id": "https://openalex.org/keywords/coronavirus-disease-2019", "display_name": "Coronavirus disease 2019 (COVID-19)", "score": 0.5871059894561768}, {"id": "https://openalex.org/keywords/severe-acute-respiratory-syndrome-coronavirus-2", "display_name": "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)", "score": 0.5868024230003357}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.5327733755111694}, {"id": "https://openalex.org/keywords/2019-20-coronavirus-outbreak", "display_name": "2019-20 coronavirus outbreak", "score": 0.5287472605705261}, {"id": "https://openalex.org/keywords/intensive-care-medicine", "display_name": "Intensive care medicine", "score": 0.415374219417572}, {"id": "https://openalex.org/keywords/virology", "display_name": "Virology", "score": 0.3999544382095337}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.27837997674942017}, {"id": "https://openalex.org/keywords/disease", "display_name": "Disease", "score": 0.0658007562160492}, {"id": "https://openalex.org/keywords/infectious-disease", "display_name": "Infectious disease (medical specialty)", "score": 0.05957302451133728}], "concepts": [{"id": "https://openalex.org/C2777557582", "wikidata": "https://www.wikidata.org/wiki/Q190016", "display_name": "Heparin", "level": 2, "score": 0.756711483001709}, {"id": "https://openalex.org/C3008058167", "wikidata": "https://www.wikidata.org/wiki/Q84263196", "display_name": "Coronavirus disease 2019 (COVID-19)", "level": 4, "score": 0.5871059894561768}, {"id": "https://openalex.org/C3007834351", "wikidata": "https://www.wikidata.org/wiki/Q82069695", "display_name": "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)", "level": 5, "score": 0.5868024230003357}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.5327733755111694}, {"id": "https://openalex.org/C3006700255", "wikidata": "https://www.wikidata.org/wiki/Q81068910", "display_name": "2019-20 coronavirus outbreak", "level": 3, "score": 0.5287472605705261}, {"id": "https://openalex.org/C177713679", "wikidata": "https://www.wikidata.org/wiki/Q679690", "display_name": "Intensive care medicine", "level": 1, "score": 0.415374219417572}, {"id": "https://openalex.org/C159047783", "wikidata": "https://www.wikidata.org/wiki/Q7215", "display_name": "Virology", "level": 1, "score": 0.3999544382095337}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.27837997674942017}, {"id": "https://openalex.org/C2779134260", "wikidata": "https://www.wikidata.org/wiki/Q12136", "display_name": "Disease", "level": 2, "score": 0.0658007562160492}, {"id": "https://openalex.org/C524204448", "wikidata": "https://www.wikidata.org/wiki/Q788926", "display_name": "Infectious disease (medical specialty)", "level": 3, "score": 0.05957302451133728}, {"id": "https://openalex.org/C116675565", "wikidata": "https://www.wikidata.org/wiki/Q3241045", "display_name": "Outbreak", "level": 2, "score": 0.0}], "mesh": [{"descriptor_ui": "D000073640", "descriptor_name": "Betacoronavirus", "qualifier_ui": "Q000302", "qualifier_name": "isolation & purification", "is_major_topic": false}, {"descriptor_ui": "D000073640", "descriptor_name": "Betacoronavirus", "qualifier_ui": "Q000302", "qualifier_name": "isolation & purification", "is_major_topic": false}, {"descriptor_ui": "D000073640", "descriptor_name": "Betacoronavirus", "qualifier_ui": "Q000302", "qualifier_name": "isolation & purification", "is_major_topic": false}, {"descriptor_ui": "D000073640", "descriptor_name": "Betacoronavirus", "qualifier_ui": "Q000472", "qualifier_name": "pathogenicity", "is_major_topic": false}, {"descriptor_ui": "D000073640", "descriptor_name": "Betacoronavirus", "qualifier_ui": "Q000472", "qualifier_name": "pathogenicity", "is_major_topic": false}, {"descriptor_ui": "D000073640", "descriptor_name": "Betacoronavirus", "qualifier_ui": "Q000472", "qualifier_name": "pathogenicity", "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086402", "descriptor_name": "SARS-CoV-2", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086402", "descriptor_name": "SARS-CoV-2", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086402", "descriptor_name": "SARS-CoV-2", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086742", "descriptor_name": "COVID-19 Testing", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086742", "descriptor_name": "COVID-19 Testing", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000086742", "descriptor_name": "COVID-19 Testing", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000925", "descriptor_name": "Anticoagulants", "qualifier_ui": "Q000627", "qualifier_name": "therapeutic use", "is_major_topic": false}, {"descriptor_ui": "D000925", "descriptor_name": "Anticoagulants", "qualifier_ui": "Q000627", "qualifier_name": "therapeutic use", "is_major_topic": false}, {"descriptor_ui": "D000925", "descriptor_name": "Anticoagulants", "qualifier_ui": "Q000627", "qualifier_name": "therapeutic use", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D004211", "descriptor_name": "Disseminated Intravascular Coagulation", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D004361", "descriptor_name": "Drug Tolerance", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D004361", "descriptor_name": "Drug Tolerance", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D004361", "descriptor_name": "Drug Tolerance", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005169", "descriptor_name": "Factor VIII", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005169", "descriptor_name": "Factor VIII", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005169", "descriptor_name": "Factor VIII", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005338", "descriptor_name": "Fibrin Fibrinogen Degradation Products", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005338", "descriptor_name": "Fibrin Fibrinogen Degradation Products", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005338", "descriptor_name": "Fibrin Fibrinogen Degradation Products", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005340", "descriptor_name": "Fibrinogen", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005340", "descriptor_name": "Fibrinogen", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D005340", "descriptor_name": "Fibrinogen", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006493", "descriptor_name": "Heparin", "qualifier_ui": "Q000627", "qualifier_name": "therapeutic use", "is_major_topic": false}, {"descriptor_ui": "D006493", "descriptor_name": "Heparin", "qualifier_ui": "Q000627", "qualifier_name": "therapeutic use", "is_major_topic": false}, {"descriptor_ui": "D006493", "descriptor_name": "Heparin", "qualifier_ui": "Q000627", "qualifier_name": "therapeutic use", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007362", "descriptor_name": "Intensive Care Units", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007362", "descriptor_name": "Intensive Care Units", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007362", "descriptor_name": "Intensive Care Units", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D011024", "descriptor_name": "Pneumonia, Viral", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D011655", "descriptor_name": "Pulmonary Embolism", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D015331", "descriptor_name": "Cohort Studies", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015331", "descriptor_name": "Cohort Studies", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015331", "descriptor_name": "Cohort Studies", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015415", "descriptor_name": "Biomarkers", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D015415", "descriptor_name": "Biomarkers", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D015415", "descriptor_name": "Biomarkers", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D015951", "descriptor_name": "Factor Xa", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D015951", "descriptor_name": "Factor Xa", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D015951", "descriptor_name": "Factor Xa", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D016903", "descriptor_name": "Drug Monitoring", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D016903", "descriptor_name": "Drug Monitoring", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D016903", "descriptor_name": "Drug Monitoring", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000150", "qualifier_name": "complications", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000175", "qualifier_name": "diagnosis", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000188", "qualifier_name": "drug therapy", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D018352", "descriptor_name": "Coronavirus Infections", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D019411", "descriptor_name": "Clinical Laboratory Techniques", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D019411", "descriptor_name": "Clinical Laboratory Techniques", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D019411", "descriptor_name": "Clinical Laboratory Techniques", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D058873", "descriptor_name": "Pandemics", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D058873", "descriptor_name": "Pandemics", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D058873", "descriptor_name": "Pandemics", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 4, "locations": [{"id": "doi:10.1111/ijlh.13230", "is_oa": true, "landing_page_url": "https://doi.org/10.1111/ijlh.13230", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13230", "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, {"id": "pmid:32311843", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/32311843", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International journal of laboratory hematology", "raw_type": null}, {"id": "pmh:oai:dspace.library.uu.nl:1874/439624", "is_oa": true, "landing_page_url": "https://dspace.library.uu.nl/handle/1874/439624", "pdf_url": null, "source": {"id": "https://openalex.org/S4306401649", "display_name": "Utrecht University Repository (Utrecht University)", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I193662353", "host_organization_name": "Utrecht University", "host_organization_lineage": ["https://openalex.org/I193662353"], "host_organization_lineage_names": [], "type": "repository"}, "license": "other-oa", "license_id": "https://openalex.org/licenses/other-oa", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": null, "raw_type": "Comment"}, {"id": "pmh:oai:pubmedcentral.nih.gov:7264532", "is_oa": true, "landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/7264532", "pdf_url": null, "source": {"id": "https://openalex.org/S2764455111", "display_name": "PubMed Central", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "Int J Lab Hematol", "raw_type": "Text"}], "best_oa_location": {"id": "doi:10.1111/ijlh.13230", "is_oa": true, "landing_page_url": "https://doi.org/10.1111/ijlh.13230", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13230", "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, "sustainable_development_goals": [{"display_name": "Good health and well-being", "id": "https://metadata.un.org/sdg/3", "score": 0.8799999952316284}], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W3016764831.pdf", "grobid_xml": "https://content.openalex.org/works/W3016764831.grobid-xml"}, "referenced_works_count": 7, "referenced_works": ["https://openalex.org/W2084877141", "https://openalex.org/W2106474407", "https://openalex.org/W2138679315", "https://openalex.org/W2414143634", "https://openalex.org/W2463444425", "https://openalex.org/W2944752046", "https://openalex.org/W3008461878"], "related_works": ["https://openalex.org/W3036314732", "https://openalex.org/W3009669391", "https://openalex.org/W4382894326", "https://openalex.org/W3198183218", "https://openalex.org/W3171943759", "https://openalex.org/W3176864053", "https://openalex.org/W3084498529", "https://openalex.org/W4206669628", "https://openalex.org/W3020699490", "https://openalex.org/W4292098121"], "abstract_inverted_index": {"In": [0, 56, 161, 326], "March": [1], "2020,": [2], "the": [3, 16, 19, 32, 44, 50, 68, 115, 124, 128, 154, 171, 212, 291, 299, 312, 317, 331, 346, 349, 368, 431, 456, 461, 484, 496, 516, 537, 547, 551, 554, 558, 562, 570, 575, 585, 593, 603, 615], "global": [4], "healthcare": [5], "system": [6], "is": [7, 15, 52, 99, 322, 468], "overwhelmed": [8], "by": [9, 123, 278, 430, 493, 507], "patients": [10, 28, 63, 82, 157, 165, 223, 253, 275, 339, 634], "infected": [11], "with": [12, 36, 101, 133, 153, 158, 173, 227, 254, 340, 584, 625, 635], "SARS-CoV-2,": [13], "which": [14], "cause": [17, 471], "of": [18, 26, 43, 49, 62, 105, 112, 117, 148, 177, 195, 200, 206, 214, 267, 304, 319, 335, 348, 455, 472, 489, 501, 572, 587, 618, 629, 638], "coronavirus": [20], "pandemic": [21], "(Covid-2019).": [22], "A": [23, 420], "large": [24], "number": [25], "these": [27, 178, 361], "end": [29], "up": [30], "in": [31, 81, 114, 156, 219, 272, 338, 360, 367, 443, 460, 485, 497, 574, 632], "intensive": [33], "care": [34], "units": [35], "critical": [37], "illness": [38], "requiring": [39, 511], "mechanical": [40], "ventilation.": [41], "One": [42], "most": [45], "important": [46], "clinical": [47, 93, 594], "features": [48], "infection": [51], "a": [53, 57, 268, 341, 469, 541, 626], "profound": [54, 118, 261], "coagulopathy.": [55], "recent": [58], "cohort": [59], "study,": [60], "71%": [61], "who": [64, 83], "eventually": [65], "died": [66], "matched": [67], "ISTH": [69], "criteria": [70], "for": [71, 146, 257, 301, 424, 545], "disseminated": [72], "intravascular": [73], "coagulation,": [74, 288], "while": [75, 452, 495], "this": [76, 97, 425], "percentage": [77, 205], "was": [78, 276, 427, 437], "only": [79], "0.6%": [80], "survived.1": [84], "Although": [85], "no": [86], "data": [87, 139, 250, 606], "have": [88, 166, 535], "been": [89, 168], "presented": [90], "or": [91, 198, 244, 265, 316, 482], "published,": [92], "experience": [94], "suggests": [95], "that": [96], "coagulopathy": [98, 119, 155, 262], "associated": [100, 152], "an": [102, 233, 255, 327, 374, 413, 525], "increased": [103, 442], "risk": [104], "both": [106], "venous": [107, 207], "and": [108, 143, 192, 239, 260, 358, 399, 448, 580, 607], "arterial": [109], "thrombosis.": [110], "Treatment": [111, 271], "thrombosis": [113], "setting": [116], "may": [120, 528], "be": [121, 217, 440], "hampered": [122], "inability": [125], "to": [126, 170, 284, 310, 329, 439, 514, 560, 591, 613], "use": [127, 586], "aPTT": [129, 234, 292, 314, 518, 642], "ratio": [130, 235, 315], "when": [131], "treating": [132], "unfractionated": [134], "heparin": [135, 150, 324, 336, 474, 490, 502, 616], "(UHF).": [136], "We": [137], "provide": [138, 144], "from": [140, 406], "our": [141, 162, 608], "center": [142], "guidance": [145], "treatment": [147, 579, 620, 639], "perceived": [149, 286], "resistance": [151, 337], "SARS-CoV-2": [159, 174, 342, 444, 605, 636], "infection.": [160], "hospital,": [163], "75": [164], "now": [167], "admitted": [169], "ICU": [172, 184], "infection,": [175, 343], "some": [176], "experiencing": [179], "serious": [180], "thromboembolic": [181, 208, 269], "complications": [182, 582], "during": [183], "stay": [185], "including": [186], "pulmonary": [187], "embolism,": [188], "ischemic-CVA,": [189], "acral": [190], "ischemia,": [191], "recurrent": [193], "clotting": [194], "dialysis": [196], "filters": [197], "oxygenators": [199], "extracorporeal": [201], "membrane": [202], "oxygenation.": [203], "The": [204, 578], "events": [209], "diagnosed": [210], "at": [211, 263], "time": [213, 559, 573], "suspicion": [215], "can": [216], "seen": [218], "Table": [220, 247], "1.": [221], "These": [222], "were": [224, 365, 410, 450, 459], "therapeutically": [225], "treated": [226], "either": [228], "UHF": [229], "intravenously": [230], "(UFH)": [231], "(with": [232], "range": [236, 565], "between": [237], "2.0": [238], "3.0": [240], "(ie,": [241], "50-75": [242], "seconds))": [243], "low\u2013molecular-weight": [245], "heparin.": [246], "2": [248], "provides": [249], "on": [251, 290, 602, 622, 641], "four": [252, 274], "indication": [256], "therapeutic": [258, 564], "anticoagulation": [259], "admission": [264], "diagnosis": [266], "event.": [270], "all": [273, 404, 454, 633], "complicated": [277], "necessitating": [279], "very": [280], "high": [281], "UFH": [282, 303, 513, 588, 619], "doses": [283], "achieve": [285, 311, 515], "adequate": [287], "based": [289, 621, 640], "ratio.": [293], "This": [294], "rare": [295], "phenomenon": [296], "defined": [297], "as": [298, 353, 491, 505, 540, 566, 568], "need": [300], "high-dose": [302, 512], "more": [305, 542], "than": [306, 550], "35": [307], "000": [308], "IU/d": [309], "target": [313, 517, 563, 576, 627], "impossibility": [318], "doing": [320], "so": [321], "called": [323], "resistance.": [325], "attempt": [328], "elucidate": [330], "possible": [332], "causal": [333], "factor(s)": [334], "we": [344, 611], "measured": [345, 366, 411, 492, 506], "levels": [347, 458, 480, 624], "coagulation-associated": [350], "factors": [351], "such": [352], "Factor": [354, 385, 389, 435, 465, 478], "VIII,": [355], "D-dimer,": [356], "fibrinogen,": [357], "antithrombin": [359, 396, 457], "patients.": [362], "Coagulation": [363], "assays": [364], "central": [369], "ISO-15189": [370], "accredited": [371], "laboratory": [372], "using": [373, 383, 412], "ACL": [375], "Top": [376], "750": [377], "LAS": [378], "coagulation": [379], "analyzer": [380, 417], "(Werfen": [381], "Diagnostics)": [382], "Coamatic": [384], "VIII": [386, 436, 466, 479], "reagent": [387, 393, 397, 402], "(chromogenic": [388], "VIII),": [390], "QFA": [391], "thrombin": [392], "(fibrinogen),": [394], "liquid": [395], "(antithrombin),": [398], "D-dimer": [400], "HS500": [401], "(D-dimer)": [403], "obtained": [405], "Werfen": [407], "diagnostics.": [408], "Platelets": [409], "Alinity": [414], "Hq": [415], "hematology": [416], "(Abbott": [418], "Diagnostics).": [419], "formal": [421], "ethics": [422, 433], "review": [423], "study": [426], "deemed": [428], "unnecessary": [429], "local": [432], "committee.": [434], "found": [438], "extremely": [441], "patients,": [445], "also": [446], "fibrinogen": [447], "d-dimer": [449], "elevated,": [451], "almost": [453], "normal": [462], "range.": [463], "High": [464], "level": [467, 539, 556], "common": [470], "apparent": [473], "resistance.2,": [475], "3": [476], "Increased": [477], "decrease": [481], "normalize": [483], "vitro": [486], "anticoagulant": [487], "activity": [488, 500, 523, 549, 617], "aPTT,": [494], "vivo": [498], "antithrombotic": [499, 522, 548], "remains": [503], "unaffected": [504], "anti-Xa": [508, 526, 538, 555, 623], "assay.4": [509], "Patients": [510], "without": [519], "monitoring": [520, 546, 581], "its": [521], "via": [524], "assay": [527], "develop": [529], "life-threatening": [530], "bleeding": [531], "complications.": [532], "Previous": [533], "studies": [534], "shown": [536], "suitable": [543], "parameter": [544], "aPTT.5-7": [552], "Monitoring": [553], "shortens": [557], "reach": [561], "well": [567], "improves": [569], "length": [571], "range.5-7": [577], "observed": [583], "necessitate": [589], "us": [590], "adjust": [592], "guidelines": [595], "used": [596], "locally": [597], "awaiting": [598], "(inter)national": [599], "guidance.": [600], "Based": [601], "limited": [604], "own": [609], "experience,": [610], "suggest": [612], "monitor": [614], "value": [628], "0.3-0.7": [630], "U/L": [631], "instead": [637], "levels.5-7": [643], "None.": [644]}, "counts_by_year": [{"year": 2025, "cited_by_count": 7}, {"year": 2024, "cited_by_count": 7}, {"year": 2023, "cited_by_count": 16}, {"year": 2022, "cited_by_count": 17}, {"year": 2021, "cited_by_count": 54}, {"year": 2020, "cited_by_count": 67}], "updated_date": "2025-11-06T03:46:38.306776", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W2135052317", "doi": "https://doi.org/10.1373/clinchem.2013.204701", "title": "Simple Paper-Based Test for Measuring Blood Hemoglobin Concentration in Resource-Limited Settings", "display_name": "Simple Paper-Based Test for Measuring Blood Hemoglobin Concentration in Resource-Limited Settings", "relevance_score": 53.91294, "publication_year": 2013, "publication_date": "2013-06-21", "ids": {"openalex": "https://openalex.org/W2135052317", "doi": "https://doi.org/10.1373/clinchem.2013.204701", "mag": "2135052317", "pmid": "https://pubmed.ncbi.nlm.nih.gov/23788584"}, "language": "en", "primary_location": {"id": "doi:10.1373/clinchem.2013.204701", "is_oa": true, "landing_page_url": "https://doi.org/10.1373/clinchem.2013.204701", "pdf_url": "http://clinchem.aaccjnls.org/content/clinchem/59/10/1506.full.pdf", "source": {"id": "https://openalex.org/S139212996", "display_name": "Clinical Chemistry", "issn_l": "0009-9147", "issn": ["0009-9147", "1530-8561"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320272", "host_organization_name": "American Association for Clinical Chemistry", "host_organization_lineage": ["https://openalex.org/P4310320272"], "host_organization_lineage_names": ["American Association for Clinical Chemistry"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Clinical Chemistry", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "bronze", "oa_url": "http://clinchem.aaccjnls.org/content/clinchem/59/10/1506.full.pdf", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5065935704", "display_name": "Xiaoxi Yang", "orcid": "https://orcid.org/0000-0002-5381-146X"}, "institutions": [{"id": "https://openalex.org/I114832834", "display_name": "Tulane University", "ror": "https://ror.org/04vmvtb21", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I114832834"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Xiaoxi Yang", "raw_affiliation_strings": ["Department of Biomedical Engineering, Tulane University, New Orleans, LA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering, Tulane University, New Orleans, LA", "institution_ids": ["https://openalex.org/I114832834"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5004051187", "display_name": "Nathaniel Z. Piety", "orcid": "https://orcid.org/0000-0002-5958-806X"}, "institutions": [{"id": "https://openalex.org/I114832834", "display_name": "Tulane University", "ror": "https://ror.org/04vmvtb21", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I114832834"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Nathaniel Z Piety", "raw_affiliation_strings": ["Department of Biomedical Engineering, Tulane University, New Orleans, LA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering, Tulane University, New Orleans, LA", "institution_ids": ["https://openalex.org/I114832834"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5064082964", "display_name": "Seth M. Vignes", "orcid": null}, "institutions": [{"id": "https://openalex.org/I114832834", "display_name": "Tulane University", "ror": "https://ror.org/04vmvtb21", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I114832834"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Seth M Vignes", "raw_affiliation_strings": ["Department of Biomedical Engineering, Tulane University, New Orleans, LA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering, Tulane University, New Orleans, LA", "institution_ids": ["https://openalex.org/I114832834"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5004448919", "display_name": "Melody Benton", "orcid": "https://orcid.org/0000-0002-9904-039X"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Melody S Benton", "raw_affiliation_strings": ["Sickle Cell Center of Southern Louisiana and"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Sickle Cell Center of Southern Louisiana and", "institution_ids": []}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5064328568", "display_name": "Julie Kanter", "orcid": "https://orcid.org/0000-0001-7002-8891"}, "institutions": [{"id": "https://openalex.org/I114832834", "display_name": "Tulane University", "ror": "https://ror.org/04vmvtb21", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I114832834"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "Julie Kanter", "raw_affiliation_strings": ["Department of Pediatrics, Section of Hematology/Oncology, Tulane University School of Medicine, New Orleans, LA", "Sickle Cell Center of Southern Louisiana and"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Pediatrics, Section of Hematology/Oncology, Tulane University School of Medicine, New Orleans, LA", "institution_ids": ["https://openalex.org/I114832834"]}, {"raw_affiliation_string": "Sickle Cell Center of Southern Louisiana and", "institution_ids": []}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5067078239", "display_name": "Sergey S. Shevkoplyas", "orcid": "https://orcid.org/0000-0002-8203-8365"}, "institutions": [{"id": "https://openalex.org/I114832834", "display_name": "Tulane University", "ror": "https://ror.org/04vmvtb21", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I114832834"]}], "countries": ["US"], "is_corresponding": true, "raw_author_name": "Sergey S Shevkoplyas", "raw_affiliation_strings": ["Department of Biomedical Engineering, Tulane University, New Orleans, LA"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Biomedical Engineering, Tulane University, New Orleans, LA", "institution_ids": ["https://openalex.org/I114832834"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 6, "corresponding_author_ids": ["https://openalex.org/A5067078239"], "corresponding_institution_ids": ["https://openalex.org/I114832834"], "apc_list": {"value": 4088, "currency": "USD", "value_usd": 4088}, "apc_paid": null, "fwci": 5.1271, "has_fulltext": false, "cited_by_count": 96, "citation_normalized_percentile": {"value": 0.95694734, "is_in_top_1_percent": false, "is_in_top_10_percent": true}, "cited_by_percentile_year": {"min": 96, "max": 99}, "biblio": {"volume": "59", "issue": "10", "first_page": "1506", "last_page": "1513"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11393", "display_name": "Biosensors and Analytical Detection", "score": 0.6380000114440918, "subfield": {"id": "https://openalex.org/subfields/2204", "display_name": "Biomedical Engineering"}, "field": {"id": "https://openalex.org/fields/22", "display_name": "Engineering"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, "topics": [{"id": "https://openalex.org/T11393", "display_name": "Biosensors and Analytical Detection", "score": 0.6380000114440918, "subfield": {"id": "https://openalex.org/subfields/2204", "display_name": "Biomedical Engineering"}, "field": {"id": "https://openalex.org/fields/22", "display_name": "Engineering"}, "domain": {"id": "https://openalex.org/domains/3", "display_name": "Physical Sciences"}}, {"id": "https://openalex.org/T10452", "display_name": "Iron Metabolism and Disorders", "score": 0.1745000034570694, "subfield": {"id": "https://openalex.org/subfields/2720", "display_name": "Hematology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12279", "display_name": "Body Composition Measurement Techniques", "score": 0.05400000140070915, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/simple", "display_name": "Simple (philosophy)", "score": 0.6332492828369141}, {"id": "https://openalex.org/keywords/hemoglobin", "display_name": "Hemoglobin", "score": 0.6247996091842651}, {"id": "https://openalex.org/keywords/test", "display_name": "Test (biology)", "score": 0.5098675489425659}, {"id": "https://openalex.org/keywords/resource", "display_name": "Resource (disambiguation)", "score": 0.43783944845199585}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.40092962980270386}, {"id": "https://openalex.org/keywords/chromatography", "display_name": "Chromatography", "score": 0.3501116633415222}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.31295084953308105}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.2830883860588074}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.2183091640472412}, {"id": "https://openalex.org/keywords/biology", "display_name": "Biology", "score": 0.16921821236610413}], "concepts": [{"id": "https://openalex.org/C2780586882", "wikidata": "https://www.wikidata.org/wiki/Q7520643", "display_name": "Simple (philosophy)", "level": 2, "score": 0.6332492828369141}, {"id": "https://openalex.org/C2778917026", "wikidata": "https://www.wikidata.org/wiki/Q43041", "display_name": "Hemoglobin", "level": 2, "score": 0.6247996091842651}, {"id": "https://openalex.org/C2777267654", "wikidata": "https://www.wikidata.org/wiki/Q3519023", "display_name": "Test (biology)", "level": 2, "score": 0.5098675489425659}, {"id": "https://openalex.org/C206345919", "wikidata": "https://www.wikidata.org/wiki/Q20380951", "display_name": "Resource (disambiguation)", "level": 2, "score": 0.43783944845199585}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.40092962980270386}, {"id": "https://openalex.org/C43617362", "wikidata": "https://www.wikidata.org/wiki/Q170050", "display_name": "Chromatography", "level": 1, "score": 0.3501116633415222}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.31295084953308105}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.2830883860588074}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.2183091640472412}, {"id": "https://openalex.org/C86803240", "wikidata": "https://www.wikidata.org/wiki/Q420", "display_name": "Biology", "level": 0, "score": 0.16921821236610413}, {"id": "https://openalex.org/C31258907", "wikidata": "https://www.wikidata.org/wiki/Q1301371", "display_name": "Computer network", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C151730666", "wikidata": "https://www.wikidata.org/wiki/Q7205", "display_name": "Paleontology", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C138885662", "wikidata": "https://www.wikidata.org/wiki/Q5891", "display_name": "Philosophy", "level": 0, "score": 0.0}, {"id": "https://openalex.org/C111472728", "wikidata": "https://www.wikidata.org/wiki/Q9471", "display_name": "Epistemology", "level": 1, "score": 0.0}], "mesh": [{"descriptor_ui": "D006454", "descriptor_name": "Hemoglobins", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006454", "descriptor_name": "Hemoglobins", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006454", "descriptor_name": "Hemoglobins", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006454", "descriptor_name": "Hemoglobins", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D010209", "descriptor_name": "Paper", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D010209", "descriptor_name": "Paper", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D010209", "descriptor_name": "Paper", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D010209", "descriptor_name": "Paper", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D046210", "descriptor_name": "Microfluidic Analytical Techniques", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D046210", "descriptor_name": "Microfluidic Analytical Techniques", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D046210", "descriptor_name": "Microfluidic Analytical Techniques", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D046210", "descriptor_name": "Microfluidic Analytical Techniques", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D059788", "descriptor_name": "Dried Blood Spot Testing", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D059788", "descriptor_name": "Dried Blood Spot Testing", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D059788", "descriptor_name": "Dried Blood Spot Testing", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D059788", "descriptor_name": "Dried Blood Spot Testing", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}], "locations_count": 3, "locations": [{"id": "doi:10.1373/clinchem.2013.204701", "is_oa": true, "landing_page_url": "https://doi.org/10.1373/clinchem.2013.204701", "pdf_url": "http://clinchem.aaccjnls.org/content/clinchem/59/10/1506.full.pdf", "source": {"id": "https://openalex.org/S139212996", "display_name": "Clinical Chemistry", "issn_l": "0009-9147", "issn": ["0009-9147", "1530-8561"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320272", "host_organization_name": "American Association for Clinical Chemistry", "host_organization_lineage": ["https://openalex.org/P4310320272"], "host_organization_lineage_names": ["American Association for Clinical Chemistry"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Clinical Chemistry", "raw_type": "journal-article"}, {"id": "pmid:23788584", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/23788584", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Clinical chemistry", "raw_type": null}, {"id": "pmh:oai:pubmedcentral.nih.gov:3880468", "is_oa": true, "landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/3880468", "pdf_url": null, "source": {"id": "https://openalex.org/S2764455111", "display_name": "PubMed Central", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "Clin Chem", "raw_type": "Text"}], "best_oa_location": {"id": "doi:10.1373/clinchem.2013.204701", "is_oa": true, "landing_page_url": "https://doi.org/10.1373/clinchem.2013.204701", "pdf_url": "http://clinchem.aaccjnls.org/content/clinchem/59/10/1506.full.pdf", "source": {"id": "https://openalex.org/S139212996", "display_name": "Clinical Chemistry", "issn_l": "0009-9147", "issn": ["0009-9147", "1530-8561"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320272", "host_organization_name": "American Association for Clinical Chemistry", "host_organization_lineage": ["https://openalex.org/P4310320272"], "host_organization_lineage_names": ["American Association for Clinical Chemistry"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Clinical Chemistry", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W2135052317.pdf", "grobid_xml": "https://content.openalex.org/works/W2135052317.grobid-xml"}, "referenced_works_count": 47, "referenced_works": ["https://openalex.org/W106848616", "https://openalex.org/W287236879", "https://openalex.org/W1565910006", "https://openalex.org/W1581660670", "https://openalex.org/W1635604571", "https://openalex.org/W1718990987", "https://openalex.org/W1943530259", "https://openalex.org/W1967620159", "https://openalex.org/W1970425225", "https://openalex.org/W1971417539", "https://openalex.org/W1976768923", "https://openalex.org/W1979694794", "https://openalex.org/W1979832242", "https://openalex.org/W1991727984", "https://openalex.org/W1999140355", "https://openalex.org/W2003128113", "https://openalex.org/W2015795623", "https://openalex.org/W2037422880", "https://openalex.org/W2044332835", "https://openalex.org/W2051615659", "https://openalex.org/W2066397089", "https://openalex.org/W2077902399", "https://openalex.org/W2078235745", "https://openalex.org/W2094746327", "https://openalex.org/W2097675715", "https://openalex.org/W2106763522", "https://openalex.org/W2114678107", "https://openalex.org/W2117360756", "https://openalex.org/W2119374724", "https://openalex.org/W2127274540", "https://openalex.org/W2127963725", "https://openalex.org/W2139823675", "https://openalex.org/W2144300409", "https://openalex.org/W2144332034", "https://openalex.org/W2150734069", "https://openalex.org/W2151698491", "https://openalex.org/W2154629024", "https://openalex.org/W2159284132", "https://openalex.org/W2160470359", "https://openalex.org/W2161108332", "https://openalex.org/W2170895924", "https://openalex.org/W2182244627", "https://openalex.org/W2465692541", "https://openalex.org/W6633657395", "https://openalex.org/W6681734239", "https://openalex.org/W6685734289", "https://openalex.org/W7074206565"], "related_works": ["https://openalex.org/W1585007175", "https://openalex.org/W2382521049", "https://openalex.org/W2144385241", "https://openalex.org/W4300101996", "https://openalex.org/W2165950148", "https://openalex.org/W4253593777", "https://openalex.org/W2951497643", "https://openalex.org/W2413574007", "https://openalex.org/W4235499160", "https://openalex.org/W2142393343"], "abstract_inverted_index": {"BACKGROUND:": [0], "The": [1, 55, 101, 113, 148, 180], "measurement": [2], "of": [3, 13, 24, 57, 67, 87, 90, 117, 130, 150, 170, 188, 206, 215, 237], "hemoglobin": [4], "concentration": [5], "([Hb])": [6], "is": [7], "performed": [8], "routinely": [9], "as": [10], "a": [11, 14, 76, 88, 108, 136], "part": [12], "complete": [15], "blood": [16, 91, 103, 119, 142], "cell": [17, 244], "count": [18], "to": [19, 29, 123], "evaluate": [20], "the": [21, 118, 128, 131, 154, 158, 167, 171, 174, 189, 207, 213, 216, 235], "oxygen-carrying": [22], "capacity": [23], "blood.": [25], "Devices": [26], "currently": [27], "available": [28], "physicians": [30], "and": [31, 43, 92, 111, 157, 198, 242], "clinical": [32], "laboratories": [33], "for": [34, 52, 80, 227, 239], "measuring": [35, 81], "[Hb]": [36, 151, 192, 200], "are": [37], "accurate,": [38], "operate": [39], "on": [40], "small": [41], "samples,": [42], "provide": [44], "results": [45], "rapidly,": [46], "but": [47, 59], "may": [48], "be": [49, 225], "prohibitively": [50], "expensive": [51], "resource-limited": [53, 231], "settings.": [54], "unavailability": [56], "accurate": [58, 183], "inexpensive": [60], "diagnostic": [61], "tools": [62], "often": [63], "precludes": [64], "proper": [65], "diagnosis": [66], "anemia": [68, 229], "in": [69, 196, 204, 230, 234, 247], "low-income": [70], "developing": [71], "countries.": [72], "Therefore,": [73], "we": [74], "developed": [75], "simple": [77], "paper-based": [78, 132, 155, 217], "assay": [79, 134, 156, 181], "[Hb].": [82, 125], "METHODS:": [83], "A": [84], "20-\u03bcL": [85], "droplet": [86], "mixture": [89], "Drabkin": [93], "reagent": [94], "was": [95, 105, 121, 177, 182], "deposited": [96], "onto": [97], "patterned": [98], "chromatography": [99], "paper.": [100], "resulting": [102], "stain": [104, 120], "digitized": [106], "with": [107, 135], "portable": [109], "scanner": [110], "analyzed.": [112], "mean": [114], "color": [115], "intensity": [116], "used": [122], "quantify": [124], "We": [126], "compared": [127], "performance": [129], "Hb": [133, 218], "hematology": [137], "analyzer": [138], "(comparison": [139], "method)": [140], "using": [141], "samples": [143], "from": [144], "54": [145], "subjects.": [146, 208], "RESULTS:": [147], "values": [149], "measured": [152], "by": [153, 193, 201], "comparison": [159], "method": [160], "were": [161], "highly": [162], "correlated": [163], "(R(2)": [164], "=": [165], "0.9598);": [166], "standard": [168], "deviation": [169], "difference": [172], "between": [173], "two": [175], "measurements": [176], "0.62": [178], "g/dL.": [179], "within": [184], "1": [185], "g/dL": [186, 195, 203], "90.7%": [187], "time,": [190], "overestimating": [191], "\u22651": [194, 202], "1.9%": [197], "underestimating": [199], "7.4%": [205], "CONCLUSIONS:": [209], "This": [210, 220], "study": [211], "demonstrates": [212], "feasibility": [214], "assay.": [219], "simple,": [221], "low-cost": [222], "test": [223], "should": [224], "useful": [226], "diagnosing": [228], "settings,": [232], "particularly": [233], "context": [236], "care": [238], "malaria,": [240], "HIV,": [241], "sickle": [243], "disease": [245], "patients": [246], "sub-Saharan": [248], "Africa.": [249]}, "counts_by_year": [{"year": 2026, "cited_by_count": 2}, {"year": 2025, "cited_by_count": 4}, {"year": 2024, "cited_by_count": 5}, {"year": 2023, "cited_by_count": 10}, {"year": 2022, "cited_by_count": 8}, {"year": 2021, "cited_by_count": 13}, {"year": 2020, "cited_by_count": 4}, {"year": 2019, "cited_by_count": 3}, {"year": 2018, "cited_by_count": 12}, {"year": 2017, "cited_by_count": 10}, {"year": 2016, "cited_by_count": 12}, {"year": 2015, "cited_by_count": 9}, {"year": 2014, "cited_by_count": 4}], "updated_date": "2026-04-29T09:16:38.111599", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W1968401252", "doi": "https://doi.org/10.1002/ajh.1074", "title": "Correlation of hematopoietic progenitor cell count determined by the SE\u20109000\u2122 automated hematology analyzer with CD34<sup>+</sup> cell count by flow cytometry in leukapheresis products", "display_name": "Correlation of hematopoietic progenitor cell count determined by the SE\u20109000\u2122 automated hematology analyzer with CD34<sup>+</sup> cell count by flow cytometry in leukapheresis products", "relevance_score": 53.426487, "publication_year": 2001, "publication_date": "2001-03-22", "ids": {"openalex": "https://openalex.org/W1968401252", "doi": "https://doi.org/10.1002/ajh.1074", "mag": "1968401252", "pmid": "https://pubmed.ncbi.nlm.nih.gov/11279656"}, "language": "en", "primary_location": {"id": "doi:10.1002/ajh.1074", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/ajh.1074", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.1074", "source": {"id": "https://openalex.org/S199810014", "display_name": "American Journal of Hematology", "issn_l": "0361-8609", "issn": ["0361-8609", "1096-8652"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Hematology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "bronze", "oa_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.1074", "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5042276732", "display_name": "Keon Uk Park", "orcid": "https://orcid.org/0000-0002-6902-7063"}, "institutions": [{"id": "https://openalex.org/I205490536", "display_name": "Dongguk University", "ror": "https://ror.org/057q6n778", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I205490536"]}], "countries": ["KR"], "is_corresponding": true, "raw_author_name": "Keon Uk Park", "raw_affiliation_strings": ["Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea. kupark@dumc.or.kr", "Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea. kupark@dumc.or.kr", "institution_ids": ["https://openalex.org/I205490536"]}, {"raw_affiliation_string": "Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea", "institution_ids": ["https://openalex.org/I205490536"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5119246470", "display_name": "Sang Hee Kim", "orcid": "https://orcid.org/0000-0002-9806-2757"}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Sang Hee Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5106084008", "display_name": "Cheolwon Suh", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Cheolwon Suh", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5101917035", "display_name": "Shin Kim", "orcid": "https://orcid.org/0000-0003-0595-8608"}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Shin Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5068993459", "display_name": "Sun Jong Lee", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Sun Jong Lee", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5006682374", "display_name": "Jung Sun Park", "orcid": "https://orcid.org/0000-0002-7562-039X"}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I205490536", "display_name": "Dongguk University", "ror": "https://ror.org/057q6n778", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I205490536"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Jung Sun Park", "raw_affiliation_strings": ["Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea", "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea", "institution_ids": ["https://openalex.org/I205490536"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5114056460", "display_name": "H. Cho", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Hwa Jung Cho", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5100334922", "display_name": "Kang-Wook Kim", "orcid": "https://orcid.org/0000-0003-1489-8264"}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Kang Wook Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5084943040", "display_name": "Keehyun Lee", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Keehyun Lee", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5100647365", "display_name": "Hyo Jung Kim", "orcid": "https://orcid.org/0000-0001-9555-0926"}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Hyo Jung Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5076115706", "display_name": "Jinny Park", "orcid": "https://orcid.org/0009-0005-3186-3591"}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I205490536", "display_name": "Dongguk University", "ror": "https://ror.org/057q6n778", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I205490536"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Jinny Park", "raw_affiliation_strings": ["Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea", "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, Dongguk University College of Medicine, Kyongju, Korea", "institution_ids": ["https://openalex.org/I205490536"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5110564546", "display_name": "Young Joo Min", "orcid": null}, "institutions": [{"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Young Joo Min", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5053594048", "display_name": "Jeong Gyoon Kim", "orcid": null}, "institutions": [{"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Jeong Gyoon Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5100745443", "display_name": "Tae\u2010Won Kim", "orcid": "https://orcid.org/0000-0001-7071-1455"}, "institutions": [{"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Taewon Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5001916257", "display_name": "Je\u2010Hwan Lee", "orcid": "https://orcid.org/0000-0002-7060-1675"}, "institutions": [{"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Je Hwan Lee", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5109892114", "display_name": "Sung Bae Kim", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Sung Bae Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5110470655", "display_name": "Sang We Kim", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Sang We Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5103880924", "display_name": "Kyoo Hyung Lee", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Kyoo Hyung Lee", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}, {"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5110200124", "display_name": "Jung Shin Lee", "orcid": null}, "institutions": [{"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Jung Shin Lee", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5111445982", "display_name": "Woo Kun Kim", "orcid": null}, "institutions": [{"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Woo Kun Kim", "raw_affiliation_strings": ["Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5056692743", "display_name": "Chan Jeong Park", "orcid": "https://orcid.org/0000-0001-8247-6333"}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Chan Jeong Park", "raw_affiliation_strings": ["Department of Clinical Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Clinical Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5111909366", "display_name": "Hyun Sook", "orcid": null}, "institutions": [{"id": "https://openalex.org/I116631150", "display_name": "Ulsan College", "ror": "https://ror.org/02tec3785", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I116631150"]}, {"id": "https://openalex.org/I2801680663", "display_name": "Asan Medical Center", "ror": "https://ror.org/03s5q0090", "country_code": "KR", "type": "healthcare", "lineage": ["https://openalex.org/I2801680663", "https://openalex.org/I4210167194"]}, {"id": "https://openalex.org/I40542001", "display_name": "University of Ulsan", "ror": "https://ror.org/02c2f8975", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I40542001"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Hyun Sook Chi", "raw_affiliation_strings": ["Department of Clinical Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Clinical Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", "institution_ids": ["https://openalex.org/I40542001", "https://openalex.org/I2801680663", "https://openalex.org/I116631150"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 22, "corresponding_author_ids": ["https://openalex.org/A5042276732"], "corresponding_institution_ids": ["https://openalex.org/I205490536"], "apc_list": {"value": 4940, "currency": "USD", "value_usd": 4940}, "apc_paid": null, "fwci": 0.7439, "has_fulltext": true, "cited_by_count": 30, "citation_normalized_percentile": {"value": 0.67689024, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 90, "max": 97}, "biblio": {"volume": "67", "issue": "1", "first_page": "42", "last_page": "47"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T10345", "display_name": "Hematopoietic Stem Cell Transplantation", "score": 0.9998000264167786, "subfield": {"id": "https://openalex.org/subfields/2720", "display_name": "Hematology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T10345", "display_name": "Hematopoietic Stem Cell Transplantation", "score": 0.9998000264167786, "subfield": {"id": "https://openalex.org/subfields/2720", "display_name": "Hematology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12172", "display_name": "Neutropenia and Cancer Infections", "score": 0.9995999932289124, "subfield": {"id": "https://openalex.org/subfields/2730", "display_name": "Oncology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.9854999780654907, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/leukapheresis", "display_name": "Leukapheresis", "score": 0.9688715934753418}, {"id": "https://openalex.org/keywords/cd34", "display_name": "CD34", "score": 0.6338672041893005}, {"id": "https://openalex.org/keywords/flow-cytometry", "display_name": "Flow cytometry", "score": 0.5821611881256104}, {"id": "https://openalex.org/keywords/stem-cell", "display_name": "Stem cell", "score": 0.5441367626190186}, {"id": "https://openalex.org/keywords/haematopoiesis", "display_name": "Haematopoiesis", "score": 0.5176073312759399}, {"id": "https://openalex.org/keywords/blood-cell", "display_name": "Blood cell", "score": 0.50633704662323}, {"id": "https://openalex.org/keywords/white-blood-cell", "display_name": "White blood cell", "score": 0.4986155033111572}, {"id": "https://openalex.org/keywords/progenitor-cell", "display_name": "Progenitor cell", "score": 0.49387699365615845}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.4840956926345825}, {"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.48372605443000793}, {"id": "https://openalex.org/keywords/peripheral-blood-mononuclear-cell", "display_name": "Peripheral blood mononuclear cell", "score": 0.48038774728775024}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.44487398862838745}, {"id": "https://openalex.org/keywords/immunology", "display_name": "Immunology", "score": 0.4408392608165741}, {"id": "https://openalex.org/keywords/cell", "display_name": "Cell", "score": 0.41146278381347656}, {"id": "https://openalex.org/keywords/andrology", "display_name": "Andrology", "score": 0.35609519481658936}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.35478293895721436}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.25768280029296875}, {"id": "https://openalex.org/keywords/biology", "display_name": "Biology", "score": 0.2431340217590332}, {"id": "https://openalex.org/keywords/in-vitro", "display_name": "In vitro", "score": 0.06979376077651978}, {"id": "https://openalex.org/keywords/biochemistry", "display_name": "Biochemistry", "score": 0.06440669298171997}], "concepts": [{"id": "https://openalex.org/C2777371436", "wikidata": "https://www.wikidata.org/wiki/Q3237071", "display_name": "Leukapheresis", "level": 4, "score": 0.9688715934753418}, {"id": "https://openalex.org/C10205521", "wikidata": "https://www.wikidata.org/wiki/Q4035578", "display_name": "CD34", "level": 3, "score": 0.6338672041893005}, {"id": "https://openalex.org/C553184892", "wikidata": "https://www.wikidata.org/wiki/Q1141429", "display_name": "Flow cytometry", "level": 2, "score": 0.5821611881256104}, {"id": "https://openalex.org/C28328180", "wikidata": "https://www.wikidata.org/wiki/Q48196", "display_name": "Stem cell", "level": 2, "score": 0.5441367626190186}, {"id": "https://openalex.org/C109159458", "wikidata": "https://www.wikidata.org/wiki/Q919283", "display_name": "Haematopoiesis", "level": 3, "score": 0.5176073312759399}, {"id": "https://openalex.org/C2779979121", "wikidata": "https://www.wikidata.org/wiki/Q211709", "display_name": "Blood cell", "level": 2, "score": 0.50633704662323}, {"id": "https://openalex.org/C2778488018", "wikidata": "https://www.wikidata.org/wiki/Q42395", "display_name": "White blood cell", "level": 2, "score": 0.4986155033111572}, {"id": "https://openalex.org/C201750760", "wikidata": "https://www.wikidata.org/wiki/Q1896218", "display_name": "Progenitor cell", "level": 3, "score": 0.49387699365615845}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.4840956926345825}, {"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.48372605443000793}, {"id": "https://openalex.org/C137061746", "wikidata": "https://www.wikidata.org/wiki/Q736033", "display_name": "Peripheral blood mononuclear cell", "level": 3, "score": 0.48038774728775024}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.44487398862838745}, {"id": "https://openalex.org/C203014093", "wikidata": "https://www.wikidata.org/wiki/Q101929", "display_name": "Immunology", "level": 1, "score": 0.4408392608165741}, {"id": "https://openalex.org/C1491633281", "wikidata": "https://www.wikidata.org/wiki/Q7868", "display_name": "Cell", "level": 2, "score": 0.41146278381347656}, {"id": "https://openalex.org/C16685009", "wikidata": "https://www.wikidata.org/wiki/Q335057", "display_name": "Andrology", "level": 1, "score": 0.35609519481658936}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.35478293895721436}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.25768280029296875}, {"id": "https://openalex.org/C86803240", "wikidata": "https://www.wikidata.org/wiki/Q420", "display_name": "Biology", "level": 0, "score": 0.2431340217590332}, {"id": "https://openalex.org/C202751555", "wikidata": "https://www.wikidata.org/wiki/Q221681", "display_name": "In vitro", "level": 2, "score": 0.06979376077651978}, {"id": "https://openalex.org/C55493867", "wikidata": "https://www.wikidata.org/wiki/Q7094", "display_name": "Biochemistry", "level": 1, "score": 0.06440669298171997}, {"id": "https://openalex.org/C54355233", "wikidata": "https://www.wikidata.org/wiki/Q7162", "display_name": "Genetics", "level": 1, "score": 0.0}], "mesh": [{"descriptor_ui": "D000293", "descriptor_name": "Adolescent", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000293", "descriptor_name": "Adolescent", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000293", "descriptor_name": "Adolescent", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001330", "descriptor_name": "Electronic Data Processing", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001330", "descriptor_name": "Electronic Data Processing", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001330", "descriptor_name": "Electronic Data Processing", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006412", "descriptor_name": "Hematopoietic Stem Cells", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D006412", "descriptor_name": "Hematopoietic Stem Cells", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D006412", "descriptor_name": "Hematopoietic Stem Cells", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D006412", "descriptor_name": "Hematopoietic Stem Cells", "qualifier_ui": "Q000276", "qualifier_name": "immunology", "is_major_topic": false}, {"descriptor_ui": "D006412", "descriptor_name": "Hematopoietic Stem Cells", "qualifier_ui": "Q000276", "qualifier_name": "immunology", "is_major_topic": false}, {"descriptor_ui": "D006412", "descriptor_name": "Hematopoietic Stem Cells", "qualifier_ui": "Q000276", "qualifier_name": "immunology", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007937", "descriptor_name": "Leukapheresis", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D007937", "descriptor_name": "Leukapheresis", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D007937", "descriptor_name": "Leukapheresis", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D007937", "descriptor_name": "Leukapheresis", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D007937", "descriptor_name": "Leukapheresis", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D007937", "descriptor_name": "Leukapheresis", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D009000", "descriptor_name": "Monocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D009000", "descriptor_name": "Monocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D009000", "descriptor_name": "Monocytes", "qualifier_ui": "Q000166", "qualifier_name": "cytology", "is_major_topic": false}, {"descriptor_ui": "D012680", "descriptor_name": "Sensitivity and Specificity", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012680", "descriptor_name": "Sensitivity and Specificity", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012680", "descriptor_name": "Sensitivity and Specificity", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015374", "descriptor_name": "Biosensing Techniques", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015374", "descriptor_name": "Biosensing Techniques", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D015374", "descriptor_name": "Biosensing Techniques", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016014", "descriptor_name": "Linear Models", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016014", "descriptor_name": "Linear Models", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016014", "descriptor_name": "Linear Models", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D018952", "descriptor_name": "Antigens, CD34", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D018952", "descriptor_name": "Antigens, CD34", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D018952", "descriptor_name": "Antigens, CD34", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "doi:10.1002/ajh.1074", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/ajh.1074", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.1074", "source": {"id": "https://openalex.org/S199810014", "display_name": "American Journal of Hematology", "issn_l": "0361-8609", "issn": ["0361-8609", "1096-8652"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Hematology", "raw_type": "journal-article"}, {"id": "pmid:11279656", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/11279656", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American journal of hematology", "raw_type": null}], "best_oa_location": {"id": "doi:10.1002/ajh.1074", "is_oa": true, "landing_page_url": "https://doi.org/10.1002/ajh.1074", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.1074", "source": {"id": "https://openalex.org/S199810014", "display_name": "American Journal of Hematology", "issn_l": "0361-8609", "issn": ["0361-8609", "1096-8652"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Hematology", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W1968401252.pdf", "grobid_xml": "https://content.openalex.org/works/W1968401252.grobid-xml"}, "referenced_works_count": 15, "referenced_works": ["https://openalex.org/W93669950", "https://openalex.org/W1484655458", "https://openalex.org/W1881943990", "https://openalex.org/W1962943827", "https://openalex.org/W2024573621", "https://openalex.org/W2049389067", "https://openalex.org/W2098052439", "https://openalex.org/W2121960093", "https://openalex.org/W2125887123", "https://openalex.org/W2254322017", "https://openalex.org/W2404842946", "https://openalex.org/W2411716823", "https://openalex.org/W2418759906", "https://openalex.org/W2439536412", "https://openalex.org/W2443421801"], "related_works": ["https://openalex.org/W1970439953", "https://openalex.org/W2739583344", "https://openalex.org/W2560061426", "https://openalex.org/W1989904659", "https://openalex.org/W2110902810", "https://openalex.org/W1986885264", "https://openalex.org/W2354377647", "https://openalex.org/W4253760981", "https://openalex.org/W3035573075", "https://openalex.org/W1577078997"], "abstract_inverted_index": {"The": [0, 44, 174, 307], "yield": [1, 101, 167, 190, 210, 257, 299], "of": [2, 20, 78, 91, 110, 320], "stem": [3, 14, 27, 104, 304, 322], "cell": [4, 15, 28, 96, 100, 105, 136, 151, 155, 166, 189, 209, 251, 256, 262, 286, 298, 305, 309, 323], "collection": [5], "after": [6, 124], "mobilization": [7, 125, 324], "is": [8, 72], "crucial": [9], "for": [10, 60], "autologous": [11, 103, 303], "peripheral": [12, 141], "blood": [13, 135, 142, 179, 321], "(PBSC)": [16], "transplantation.": [17], "Quantitative": [18], "determinations": [19], "CD34(+)": [21, 99, 165, 188, 208, 250, 255, 297], "cells": [22, 63, 67, 93, 180], "using": [23], "flow": [24, 162], "cytometry": [25, 163], "or": [26, 131], "culture": [29], "have": [30], "been": [31], "used,": [32], "but": [33], "these": [34], "methods": [35], "require": [36], "much": [37], "time,": [38], "technical": [39], "experience,": [40], "and": [41, 83, 94, 129, 153, 161, 187, 234, 270, 317, 325], "expensive": [42], "reagents.": [43], "automated": [45, 158, 290], "hematology": [46, 159, 291], "analyzer": [47, 160, 292], "(Sysmex": [48], "SE-9000trade": [49], "mark,": [50], "TOA,": [51], "Japan)": [52], "equipped": [53], "with": [54, 98, 127, 207, 249, 260, 295], "the": [55, 76, 89, 171, 289, 296], "Immature": [56], "Information": [57], "(IMI)": [58], "channel": [59], "immature": [61], "myeloid": [62], "can": [64], "detect": [65], "IMI(+)": [66, 92, 154, 184, 261, 285, 308], "within": [68], "90": [69], "sec.": [70], "Detection": [71], "made": [73], "possible": [74], "by": [75, 157, 197, 275, 288], "combination": [77], "a": [79, 108, 192, 212, 225, 240, 276, 301, 315], "special": [80], "reagent": [81], "system": [82], "direct": [84], "current/radiofrequency": [85], "biosensors.": [86], "We": [87], "studied": [88], "relation": [90], "variable": [95], "counts": [97, 137, 156], "in": [102, 191, 211, 236, 300], "harvest.": [106, 306], "In": [107, 253], "series": [109], "32": [111], "patients": [112], "(median": [113], "age,": [114], "44": [115], "years;": [116], "M:F": [117], "=": [118, 216, 219, 229, 232, 244, 247, 265, 268, 281], "11:21),": [119], "184": [120], "leukaphereses": [121], "were": [122, 138, 168], "performed": [123], "regimens": [126], "chemotherapy": [128], "G-CSF": [130, 132], "alone.": [133], "Full": [134], "enumerated": [139], "on": [140, 170], "(PB)": [143], "samples": [144], "taken": [145], "prior": [146], "to": [147], "each": [148], "leukapheresis.": [149], "Mononuclear": [150], "(MNC)": [152], "based": [164], "measured": [169], "harvested": [172], "product.": [173], "relationship": [175], "among": [176], "PB": [177, 182, 201, 221], "white": [178], "(WBC),": [181], "monocytes,": [183], "cells,": [185], "MNC,": [186], "single": [193, 213], "leukapheresis": [194, 214], "was": [195], "estimated": [196], "Pearson": [198], "correlation": [199, 206, 227, 242], "analysis.": [200], "WBC": [202], "count": [203, 223, 263, 310], "showed": [204, 224, 239], "no": [205], "(r": [215, 228, 243, 264], "0.02,": [217], "P": [218, 231, 246, 267], "0.81).": [220], "monocyte": [222], "weak": [226, 241], "0.21,": [230], "0.01)": [233], "MNC": [235], "harvest": [237], "also": [238], "0.36,": [245], "0.0001)": [248], "yield.": [252], "contrast,": [254], "correlated": [258, 293], "well": [259, 294], "0.68,": [266], "0.0001),": [269], "data": [271], "could": [272], "be": [273, 312], "fitted": [274], "linear": [277], "regression": [278], "equation,": [279], "y": [280], "0.330": [282], "+": [283], "0.974x.": [284], "assay": [287], "mobilized": [302], "might": [311], "used": [313], "as": [314], "simple": [316], "efficient": [318], "indicator": [319], "collection.": [326]}, "counts_by_year": [{"year": 2024, "cited_by_count": 3}, {"year": 2022, "cited_by_count": 2}, {"year": 2021, "cited_by_count": 2}, {"year": 2020, "cited_by_count": 2}, {"year": 2017, "cited_by_count": 2}, {"year": 2013, "cited_by_count": 1}, {"year": 2012, "cited_by_count": 2}], "updated_date": "2026-05-03T08:25:01.440150", "created_date": "2016-06-24T00:00:00"}, {"id": "https://openalex.org/W2476275075", "doi": "https://doi.org/10.1016/b978-012074903-4/50008-x", "title": "Clinical Pathology of the Rat", "display_name": "Clinical Pathology of the Rat", "relevance_score": 51.85141, "publication_year": 2006, "publication_date": "2006-01-01", "ids": {"openalex": "https://openalex.org/W2476275075", "doi": "https://doi.org/10.1016/b978-012074903-4/50008-x", "mag": "2476275075"}, "language": "en", "primary_location": {"id": "doi:10.1016/b978-012074903-4/50008-x", "is_oa": false, "landing_page_url": "https://doi.org/10.1016/b978-012074903-4/50008-x", "pdf_url": null, "source": {"id": "https://openalex.org/S4306463230", "display_name": "Elsevier eBooks", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/P4310320990", "host_organization_name": "Elsevier BV", "host_organization_lineage": ["https://openalex.org/P4310320990"], "host_organization_lineage_names": ["Elsevier BV"], "type": "ebook platform"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "The Laboratory Rat", "raw_type": "book-chapter"}, "type": "book-chapter", "indexed_in": ["crossref"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5001291631", "display_name": "Bruce D. Car", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": true, "raw_author_name": "Bruce D. Car", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5063181450", "display_name": "Vicki M. Eng", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Vicki M. Eng", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5048112209", "display_name": "Nancy Everds", "orcid": "https://orcid.org/0000-0003-4910-4401"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Nancy E. Everds", "raw_affiliation_strings": [], "affiliations": []}, {"author_position": "last", "author": {"id": "https://openalex.org/A5000857059", "display_name": "Denise I. Bounous", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Denise I. Bounous", "raw_affiliation_strings": [], "affiliations": []}], "institutions": [], "countries_distinct_count": 0, "institutions_distinct_count": 4, "corresponding_author_ids": ["https://openalex.org/A5001291631"], "corresponding_institution_ids": [], "apc_list": null, "apc_paid": null, "fwci": 3.6836, "has_fulltext": false, "cited_by_count": 50, "citation_normalized_percentile": {"value": 0.93214692, "is_in_top_1_percent": false, "is_in_top_10_percent": true}, "cited_by_percentile_year": {"min": 89, "max": 99}, "biblio": {"volume": null, "issue": null, "first_page": "127", "last_page": "146"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T10836", "display_name": "Metabolomics and Mass Spectrometry Studies", "score": 0.996999979019165, "subfield": {"id": "https://openalex.org/subfields/1312", "display_name": "Molecular Biology"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, "topics": [{"id": "https://openalex.org/T10836", "display_name": "Metabolomics and Mass Spectrometry Studies", "score": 0.996999979019165, "subfield": {"id": "https://openalex.org/subfields/1312", "display_name": "Molecular Biology"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T14072", "display_name": "Immunotoxicology and immune responses", "score": 0.9753999710083008, "subfield": {"id": "https://openalex.org/subfields/2403", "display_name": "Immunology"}, "field": {"id": "https://openalex.org/fields/24", "display_name": "Immunology and Microbiology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T12281", "display_name": "Animal testing and alternatives", "score": 0.9692999720573425, "subfield": {"id": "https://openalex.org/subfields/3404", "display_name": "Small Animals"}, "field": {"id": "https://openalex.org/fields/34", "display_name": "Veterinary"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.7738872766494751}, {"id": "https://openalex.org/keywords/clinical-pathology", "display_name": "Clinical pathology", "score": 0.6828007698059082}, {"id": "https://openalex.org/keywords/bone-marrow", "display_name": "Bone marrow", "score": 0.670755922794342}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.6530905961990356}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.5632158517837524}, {"id": "https://openalex.org/keywords/peripheral-blood", "display_name": "Peripheral blood", "score": 0.5564155578613281}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.534301221370697}, {"id": "https://openalex.org/keywords/blood-smear", "display_name": "Blood smear", "score": 0.4488506615161896}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.29278427362442017}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.7738872766494751}, {"id": "https://openalex.org/C529978579", "wikidata": "https://www.wikidata.org/wiki/Q499500", "display_name": "Clinical pathology", "level": 2, "score": 0.6828007698059082}, {"id": "https://openalex.org/C2780007613", "wikidata": "https://www.wikidata.org/wiki/Q546523", "display_name": "Bone marrow", "level": 2, "score": 0.670755922794342}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.6530905961990356}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.5632158517837524}, {"id": "https://openalex.org/C3017910909", "wikidata": "https://www.wikidata.org/wiki/Q618363", "display_name": "Peripheral blood", "level": 2, "score": 0.5564155578613281}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.534301221370697}, {"id": "https://openalex.org/C3017819844", "wikidata": "https://www.wikidata.org/wiki/Q886475", "display_name": "Blood smear", "level": 3, "score": 0.4488506615161896}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.29278427362442017}, {"id": "https://openalex.org/C2778048844", "wikidata": "https://www.wikidata.org/wiki/Q12156", "display_name": "Malaria", "level": 2, "score": 0.0}], "mesh": [], "locations_count": 1, "locations": [{"id": "doi:10.1016/b978-012074903-4/50008-x", "is_oa": false, "landing_page_url": "https://doi.org/10.1016/b978-012074903-4/50008-x", "pdf_url": null, "source": {"id": "https://openalex.org/S4306463230", "display_name": "Elsevier eBooks", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/P4310320990", "host_organization_name": "Elsevier BV", "host_organization_lineage": ["https://openalex.org/P4310320990"], "host_organization_lineage_names": ["Elsevier BV"], "type": "ebook platform"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "The Laboratory Rat", "raw_type": "book-chapter"}], "best_oa_location": null, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 138, "referenced_works": ["https://openalex.org/W6380537", "https://openalex.org/W61170847", "https://openalex.org/W87798823", "https://openalex.org/W98412749", "https://openalex.org/W103031474", "https://openalex.org/W129759052", "https://openalex.org/W141909973", "https://openalex.org/W149118906", "https://openalex.org/W155771382", "https://openalex.org/W163874361", "https://openalex.org/W289589996", "https://openalex.org/W334103292", "https://openalex.org/W1500356450", "https://openalex.org/W1560965218", "https://openalex.org/W1570782716", "https://openalex.org/W1772414464", "https://openalex.org/W1797956629", "https://openalex.org/W1825835749", "https://openalex.org/W1868530020", "https://openalex.org/W1967190216", "https://openalex.org/W1972598377", "https://openalex.org/W1977508213", "https://openalex.org/W1981032465", "https://openalex.org/W1981949131", "https://openalex.org/W1982330741", "https://openalex.org/W1987336591", "https://openalex.org/W1988810247", "https://openalex.org/W1990606304", "https://openalex.org/W1991319581", "https://openalex.org/W1992417825", "https://openalex.org/W2004372526", "https://openalex.org/W2004857711", "https://openalex.org/W2007177579", "https://openalex.org/W2008628596", "https://openalex.org/W2009451529", "https://openalex.org/W2016239608", "https://openalex.org/W2016837584", "https://openalex.org/W2016984654", "https://openalex.org/W2018912133", "https://openalex.org/W2021010592", "https://openalex.org/W2021542321", "https://openalex.org/W2023483282", "https://openalex.org/W2024202109", "https://openalex.org/W2026890404", "https://openalex.org/W2028844570", "https://openalex.org/W2028930741", "https://openalex.org/W2029859292", "https://openalex.org/W2032678465", "https://openalex.org/W2035615840", "https://openalex.org/W2036373055", "https://openalex.org/W2043631859", "https://openalex.org/W2044441641", "https://openalex.org/W2047152993", "https://openalex.org/W2047393074", "https://openalex.org/W2049180550", "https://openalex.org/W2049316691", "https://openalex.org/W2049659899", "https://openalex.org/W2055267476", "https://openalex.org/W2055371274", "https://openalex.org/W2064443124", "https://openalex.org/W2071761385", "https://openalex.org/W2072365579", "https://openalex.org/W2077800244", "https://openalex.org/W2086229992", "https://openalex.org/W2086603157", "https://openalex.org/W2086994691", "https://openalex.org/W2088617309", "https://openalex.org/W2089827209", "https://openalex.org/W2090467384", "https://openalex.org/W2095985379", "https://openalex.org/W2097144160", "https://openalex.org/W2100890647", "https://openalex.org/W2105256758", "https://openalex.org/W2111159135", "https://openalex.org/W2111494667", "https://openalex.org/W2113627501", "https://openalex.org/W2115932544", "https://openalex.org/W2116694253", "https://openalex.org/W2119673466", "https://openalex.org/W2120694471", "https://openalex.org/W2125847991", "https://openalex.org/W2126602630", "https://openalex.org/W2129182154", "https://openalex.org/W2129314769", "https://openalex.org/W2130684966", "https://openalex.org/W2132798984", "https://openalex.org/W2133889126", "https://openalex.org/W2135798900", "https://openalex.org/W2142503533", "https://openalex.org/W2150668332", "https://openalex.org/W2156774939", "https://openalex.org/W2157190168", "https://openalex.org/W2165391836", "https://openalex.org/W2166520502", "https://openalex.org/W2167559937", "https://openalex.org/W2167959896", "https://openalex.org/W2195308606", "https://openalex.org/W2254837471", "https://openalex.org/W2269289618", "https://openalex.org/W2277895682", "https://openalex.org/W2291611461", "https://openalex.org/W2317184793", "https://openalex.org/W2319488049", "https://openalex.org/W2337743268", "https://openalex.org/W2404961279", "https://openalex.org/W2407558360", "https://openalex.org/W2410354548", "https://openalex.org/W2410967142", "https://openalex.org/W2411054181", "https://openalex.org/W2412486105", "https://openalex.org/W2413424590", "https://openalex.org/W2418044356", "https://openalex.org/W2428128417", "https://openalex.org/W2429539962", "https://openalex.org/W2434259415", "https://openalex.org/W2461677664", "https://openalex.org/W2551121400", "https://openalex.org/W2765276880", "https://openalex.org/W2887994263", "https://openalex.org/W2896560395", "https://openalex.org/W2970340375", "https://openalex.org/W3042098621", "https://openalex.org/W3149477829", "https://openalex.org/W4250440111", "https://openalex.org/W4254165936", "https://openalex.org/W6601295001", "https://openalex.org/W6601448543", "https://openalex.org/W6603542860", "https://openalex.org/W6652667629", "https://openalex.org/W6655520291", "https://openalex.org/W6655699130", "https://openalex.org/W6663065765", "https://openalex.org/W6715013284", "https://openalex.org/W6715358225", "https://openalex.org/W6716880899", "https://openalex.org/W6726347157", "https://openalex.org/W6729750405", "https://openalex.org/W6755918044"], "related_works": ["https://openalex.org/W2355540433", "https://openalex.org/W2382399836", "https://openalex.org/W2367999640", "https://openalex.org/W4377193851", "https://openalex.org/W4386124359", "https://openalex.org/W2749427721", "https://openalex.org/W2349723527", "https://openalex.org/W1590158237", "https://openalex.org/W2379739814", "https://openalex.org/W2368144026"], "abstract_inverted_index": null, "counts_by_year": [{"year": 2025, "cited_by_count": 3}, {"year": 2024, "cited_by_count": 1}, {"year": 2023, "cited_by_count": 5}, {"year": 2022, "cited_by_count": 2}, {"year": 2021, "cited_by_count": 1}, {"year": 2020, "cited_by_count": 2}, {"year": 2019, "cited_by_count": 2}, {"year": 2017, "cited_by_count": 6}, {"year": 2016, "cited_by_count": 3}, {"year": 2015, "cited_by_count": 3}, {"year": 2014, "cited_by_count": 4}, {"year": 2013, "cited_by_count": 5}, {"year": 2012, "cited_by_count": 3}], "updated_date": "2025-11-06T03:46:38.306776", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W2145367316", "doi": "https://doi.org/10.5045/br.2014.49.2.120", "title": "White blood cell differential counts in severely leukopenic samples: a comparative analysis of different solutions available in modern laboratory hematology", "display_name": "White blood cell differential counts in severely leukopenic samples: a comparative analysis of different solutions available in modern laboratory hematology", "relevance_score": 51.46846, "publication_year": 2014, "publication_date": "2014-01-01", "ids": {"openalex": "https://openalex.org/W2145367316", "doi": "https://doi.org/10.5045/br.2014.49.2.120", "mag": "2145367316", "pmid": "https://pubmed.ncbi.nlm.nih.gov/25025014"}, "language": "en", "primary_location": {"id": "doi:10.5045/br.2014.49.2.120", "is_oa": true, "landing_page_url": "https://doi.org/10.5045/br.2014.49.2.120", "pdf_url": "https://synapse.koreamed.org/upload/SynapseXML/3072br/pdf/br-49-120.pdf", "source": {"id": "https://openalex.org/S2764367232", "display_name": "Blood Research", "issn_l": "2287-979X", "issn": ["2287-979X", "2288-0011"], "is_oa": false, "is_in_doaj": true, "is_core": true, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "journal"}, "license": "cc-by-nc", "license_id": "https://openalex.org/licenses/cc-by-nc", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Blood Research", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "doaj", "pubmed"], "open_access": {"is_oa": true, "oa_status": "hybrid", "oa_url": "https://synapse.koreamed.org/upload/SynapseXML/3072br/pdf/br-49-120.pdf", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5030444548", "display_name": "Ah Hyun Kim", "orcid": null}, "institutions": [{"id": "https://openalex.org/I87111246", "display_name": "Catholic University of Korea", "ror": "https://ror.org/01fpnj063", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I87111246"]}], "countries": ["KR"], "is_corresponding": true, "raw_author_name": "Ah Hyun Kim", "raw_affiliation_strings": ["Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea", "institution_ids": ["https://openalex.org/I87111246"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5091582765", "display_name": "Wonbae Lee", "orcid": "https://orcid.org/0000-0002-3886-1514"}, "institutions": [{"id": "https://openalex.org/I87111246", "display_name": "Catholic University of Korea", "ror": "https://ror.org/01fpnj063", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I87111246"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Wonbae Lee", "raw_affiliation_strings": ["Department of Pediatrics, The Catholic University of Korea, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Pediatrics, The Catholic University of Korea, Seoul, Korea", "institution_ids": ["https://openalex.org/I87111246"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5043910009", "display_name": "Myungshin Kim", "orcid": "https://orcid.org/0000-0001-8632-0168"}, "institutions": [{"id": "https://openalex.org/I87111246", "display_name": "Catholic University of Korea", "ror": "https://ror.org/01fpnj063", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I87111246"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Myungshin Kim", "raw_affiliation_strings": ["Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea", "institution_ids": ["https://openalex.org/I87111246"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5021499196", "display_name": "Yonggoo Kim", "orcid": "https://orcid.org/0000-0003-2808-3795"}, "institutions": [{"id": "https://openalex.org/I87111246", "display_name": "Catholic University of Korea", "ror": "https://ror.org/01fpnj063", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I87111246"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Yonggoo Kim", "raw_affiliation_strings": ["Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea", "institution_ids": ["https://openalex.org/I87111246"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5101463799", "display_name": "Kyungja Han", "orcid": "https://orcid.org/0000-0003-4960-3403"}, "institutions": [{"id": "https://openalex.org/I87111246", "display_name": "Catholic University of Korea", "ror": "https://ror.org/01fpnj063", "country_code": "KR", "type": "education", "lineage": ["https://openalex.org/I87111246"]}], "countries": ["KR"], "is_corresponding": false, "raw_author_name": "Kyungja Han", "raw_affiliation_strings": ["Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea", "institution_ids": ["https://openalex.org/I87111246"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 5, "corresponding_author_ids": ["https://openalex.org/A5030444548"], "corresponding_institution_ids": ["https://openalex.org/I87111246"], "apc_list": null, "apc_paid": null, "fwci": 1.0525, "has_fulltext": true, "cited_by_count": 25, "citation_normalized_percentile": {"value": 0.77281182, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 98}, "biblio": {"volume": "49", "issue": "2", "first_page": "120", "last_page": "120"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.6535999774932861, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.6535999774932861, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12172", "display_name": "Neutropenia and Cancer Infections", "score": 0.1282999962568283, "subfield": {"id": "https://openalex.org/subfields/2730", "display_name": "Oncology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T12919", "display_name": "Blood disorders and treatments", "score": 0.06759999692440033, "subfield": {"id": "https://openalex.org/subfields/1311", "display_name": "Genetics"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.8738340139389038}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.8131002187728882}, {"id": "https://openalex.org/keywords/white-blood-cell", "display_name": "White blood cell", "score": 0.7113099098205566}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.5897184610366821}, {"id": "https://openalex.org/keywords/leukopenia", "display_name": "Leukopenia", "score": 0.49625450372695923}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.4176154136657715}, {"id": "https://openalex.org/keywords/lymphocyte", "display_name": "Lymphocyte", "score": 0.4100416302680969}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.3587629795074463}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.8738340139389038}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.8131002187728882}, {"id": "https://openalex.org/C2778488018", "wikidata": "https://www.wikidata.org/wiki/Q42395", "display_name": "White blood cell", "level": 2, "score": 0.7113099098205566}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.5897184610366821}, {"id": "https://openalex.org/C2780873365", "wikidata": "https://www.wikidata.org/wiki/Q496812", "display_name": "Leukopenia", "level": 3, "score": 0.49625450372695923}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.4176154136657715}, {"id": "https://openalex.org/C2777761686", "wikidata": "https://www.wikidata.org/wiki/Q715347", "display_name": "Lymphocyte", "level": 2, "score": 0.4100416302680969}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.3587629795074463}, {"id": "https://openalex.org/C2776694085", "wikidata": "https://www.wikidata.org/wiki/Q974135", "display_name": "Chemotherapy", "level": 2, "score": 0.0}], "mesh": [], "locations_count": 3, "locations": [{"id": "doi:10.5045/br.2014.49.2.120", "is_oa": true, "landing_page_url": "https://doi.org/10.5045/br.2014.49.2.120", "pdf_url": "https://synapse.koreamed.org/upload/SynapseXML/3072br/pdf/br-49-120.pdf", "source": {"id": "https://openalex.org/S2764367232", "display_name": "Blood Research", "issn_l": "2287-979X", "issn": ["2287-979X", "2288-0011"], "is_oa": false, "is_in_doaj": true, "is_core": true, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "journal"}, "license": "cc-by-nc", "license_id": "https://openalex.org/licenses/cc-by-nc", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Blood Research", "raw_type": "journal-article"}, {"id": "pmid:25025014", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/25025014", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Blood research", "raw_type": null}, {"id": "pmh:oai:pubmedcentral.nih.gov:4090333", "is_oa": true, "landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/4090333", "pdf_url": null, "source": {"id": "https://openalex.org/S2764455111", "display_name": "PubMed Central", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "Blood Res", "raw_type": "Text"}], "best_oa_location": {"id": "doi:10.5045/br.2014.49.2.120", "is_oa": true, "landing_page_url": "https://doi.org/10.5045/br.2014.49.2.120", "pdf_url": "https://synapse.koreamed.org/upload/SynapseXML/3072br/pdf/br-49-120.pdf", "source": {"id": "https://openalex.org/S2764367232", "display_name": "Blood Research", "issn_l": "2287-979X", "issn": ["2287-979X", "2288-0011"], "is_oa": false, "is_in_doaj": true, "is_core": true, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "journal"}, "license": "cc-by-nc", "license_id": "https://openalex.org/licenses/cc-by-nc", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Blood Research", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W2145367316.pdf", "grobid_xml": "https://content.openalex.org/works/W2145367316.grobid-xml"}, "referenced_works_count": 23, "referenced_works": ["https://openalex.org/W1765408815", "https://openalex.org/W1783814594", "https://openalex.org/W1915279366", "https://openalex.org/W1923273815", "https://openalex.org/W1975279466", "https://openalex.org/W1989608827", "https://openalex.org/W1997818950", "https://openalex.org/W2000869002", "https://openalex.org/W2004804759", "https://openalex.org/W2025031772", "https://openalex.org/W2035479050", "https://openalex.org/W2043803673", "https://openalex.org/W2084781106", "https://openalex.org/W2085664496", "https://openalex.org/W2094775910", "https://openalex.org/W2106572697", "https://openalex.org/W2132785906", "https://openalex.org/W2133929874", "https://openalex.org/W2136238015", "https://openalex.org/W2136796840", "https://openalex.org/W2144540515", "https://openalex.org/W2413329463", "https://openalex.org/W4239128565"], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W3114788508", "https://openalex.org/W2352314160", "https://openalex.org/W1970439953", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2419739346", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W2364979530"], "abstract_inverted_index": {"BACKGROUND:": [0], "We": [1], "evaluated": [2], "the": [3, 17, 27, 56, 68, 82, 95, 108, 148, 158, 164, 215], "efficacy": [4], "of": [5, 41, 81, 147, 170, 188, 204, 217], "white": [6], "blood": [7, 34], "cell": [8], "(WBC)": [9], "differential": [10, 46], "counts": [11, 40, 47, 63, 84, 120, 137, 187, 201], "in": [12, 50, 141, 163, 182, 202], "severely": [13, 189], "leukopenic": [14, 190], "samples": [15, 35, 191], "by": [16, 21, 85, 107, 116, 157, 178, 230], "Hematoflow": [18, 45, 109, 119, 159, 179, 186, 211], "method": [19, 110, 160, 212], "and": [20, 25, 59, 73, 89, 103, 130, 144, 194, 207], "automated": [22, 76, 128], "hematology": [23, 77, 87], "analyzers": [24], "compared": [26], "results": [28], "with": [29, 38, 127, 135, 174, 199], "manual": [30, 83, 96, 117, 136, 165, 183, 200], "counts.": [31, 97, 184, 209], "METHODS:": [32], "EDTA-anticoagulated": [33], "(175": [36], "samples)": [37], "WBC": [39], "40-990/\u00b5L": [42], "were": [43, 48, 64, 92, 111, 121, 192], "selected.": [44], "performed": [49, 66], "duplicates": [51], "employing": [52], "flow": [53], "cytometry": [54], "using": [55, 67], "CytoDiff": [57], "reagent": [58], "analysis": [60, 101], "software.": [61], "Differential": [62], "also": [65, 131, 213], "DxH": [69], "800": [70], "(Beckman": [71], "Coulter)": [72], "XE-2100": [74], "(Sysmex)": [75], "analyzers.": [78], "The": [79, 99, 210], "sum": [80], "a": [86, 90, 124, 196], "technician": [88], "resident": [91], "used": [93], "as": [94, 155], "RESULTS:": [98], "total": [100], "time": [102, 105], "hands-on": [104], "required": [106, 115], "shorter": [112], "than": [113, 152], "those": [114], "counting.": [118], "reproducible,": [122], "showed": [123, 132, 195], "good": [125, 197], "correlation": [126, 134, 198], "analyzers,": [129], "strong": [133], "(r": [138], ">": [139], "0.8)": [140], "neutrophils,": [142], "lymphocytes,": [143], "monocytes.": [145], "None": [146], "cases": [149, 169, 172], "containing": [150], "less": [151], "4%": [153, 176, 226], "blasts": [154, 162, 177, 181, 227], "analyzed": [156], "had": [161, 180], "counts,": [166], "but": [167], "8": [168], "21": [171], "(38.1%)": [173], "over": [175, 225], "CONCLUSION:": [185], "reproducible": [193], "terms": [203], "neutrophil,": [205], "lymphocyte,": [206], "monocyte": [208], "detected": [214], "presence": [216], "blasts.": [218], "Manual": [219], "slide": [220], "review": [221], "is": [222], "recommended": [223], "when": [224], "are": [228], "found": [229], "Hematoflow.": [231]}, "counts_by_year": [{"year": 2024, "cited_by_count": 2}, {"year": 2023, "cited_by_count": 1}, {"year": 2022, "cited_by_count": 4}, {"year": 2021, "cited_by_count": 2}, {"year": 2020, "cited_by_count": 1}, {"year": 2019, "cited_by_count": 4}, {"year": 2018, "cited_by_count": 5}, {"year": 2017, "cited_by_count": 2}, {"year": 2016, "cited_by_count": 3}, {"year": 2014, "cited_by_count": 1}], "updated_date": "2026-04-29T09:16:38.111599", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W3026179396", "doi": "https://doi.org/10.1111/ijlh.13244", "title": "Involvement of ADAMTS13 and von Willebrand factor in thromboembolic events in patients infected with SARS\u2010CoV\u20102", "display_name": "Involvement of ADAMTS13 and von Willebrand factor in thromboembolic events in patients infected with SARS\u2010CoV\u20102", "relevance_score": 49.400204, "publication_year": 2020, "publication_date": "2020-05-22", "ids": {"openalex": "https://openalex.org/W3026179396", "doi": "https://doi.org/10.1111/ijlh.13244", "mag": "3026179396", "pmid": "https://pubmed.ncbi.nlm.nih.gov/32441844"}, "language": "en", "primary_location": {"id": "doi:10.1111/ijlh.13244", "is_oa": true, "landing_page_url": "https://doi.org/10.1111/ijlh.13244", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13244", "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "hybrid", "oa_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13244", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5012927400", "display_name": "Albert Huisman", "orcid": "https://orcid.org/0000-0002-2291-2487"}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": true, "raw_author_name": "Albert Huisman", "raw_affiliation_strings": ["Department of Clinical Chemistry and Laboratory Medicine University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "Department of Clinical Chemistry and Laboratory Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands"], "raw_orcid": "https://orcid.org/0000-0002-2291-2487", "affiliations": [{"raw_affiliation_string": "Department of Clinical Chemistry and Laboratory Medicine University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Clinical Chemistry and Laboratory Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5079712124", "display_name": "Robert Beun", "orcid": null}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Robert Beun", "raw_affiliation_strings": ["Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5060537433", "display_name": "Maaike A. Sikma", "orcid": "https://orcid.org/0000-0003-3872-5771"}, "institutions": [{"id": "https://openalex.org/I193662353", "display_name": "Utrecht University", "ror": "https://ror.org/04pp8hn57", "country_code": "NL", "type": "education", "lineage": ["https://openalex.org/I193662353"]}, {"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Maaike Sikma", "raw_affiliation_strings": ["Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "Dutch Poisons Information Center University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands", "Dutch Poisons Information Center, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands"], "raw_orcid": "https://orcid.org/0000-0003-3872-5771", "affiliations": [{"raw_affiliation_string": "Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Dutch Poisons Information Center University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "institution_ids": ["https://openalex.org/I3018483916", "https://openalex.org/I193662353"]}, {"raw_affiliation_string": "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Dutch Poisons Information Center, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5032480026", "display_name": "Jan Westerink", "orcid": "https://orcid.org/0000-0001-5021-5227"}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Jan Westerink", "raw_affiliation_strings": ["Department of Vascular Medicine University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "Department of Vascular Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Vascular Medicine University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Vascular Medicine, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5077627178", "display_name": "Nuray Ku\u015fadasi", "orcid": "https://orcid.org/0000-0003-3504-0996"}, "institutions": [{"id": "https://openalex.org/I3018483916", "display_name": "University Medical Center Utrecht", "ror": "https://ror.org/0575yy874", "country_code": "NL", "type": "healthcare", "lineage": ["https://openalex.org/I3018483916"]}], "countries": ["NL"], "is_corresponding": false, "raw_author_name": "Nuray Kusadasi", "raw_affiliation_strings": ["Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Intensive Care University Medical Center Utrecht and University Utrecht Utrecht The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}, {"raw_affiliation_string": "Department of Intensive Care, University Medical Center Utrecht and University Utrecht, Utrecht, The Netherlands", "institution_ids": ["https://openalex.org/I3018483916"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 5, "corresponding_author_ids": ["https://openalex.org/A5012927400"], "corresponding_institution_ids": ["https://openalex.org/I3018483916"], "apc_list": {"value": 3550, "currency": "USD", "value_usd": 3550}, "apc_paid": {"value": 3550, "currency": "USD", "value_usd": 3550}, "fwci": 5.7731, "has_fulltext": false, "cited_by_count": 74, "citation_normalized_percentile": {"value": 0.97129337, "is_in_top_1_percent": false, "is_in_top_10_percent": true}, "cited_by_percentile_year": {"min": 90, "max": 100}, "biblio": {"volume": "42", "issue": "5", "first_page": "e211", "last_page": "e212"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T10993", "display_name": "Complement system in diseases", "score": 0.9994000196456909, "subfield": {"id": "https://openalex.org/subfields/2403", "display_name": "Immunology"}, "field": {"id": "https://openalex.org/fields/24", "display_name": "Immunology and Microbiology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, "topics": [{"id": "https://openalex.org/T10993", "display_name": "Complement system in diseases", "score": 0.9994000196456909, "subfield": {"id": "https://openalex.org/subfields/2403", "display_name": "Immunology"}, "field": {"id": "https://openalex.org/fields/24", "display_name": "Immunology and Microbiology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T12735", "display_name": "Blood donation and transfusion practices", "score": 0.9865000247955322, "subfield": {"id": "https://openalex.org/subfields/1405", "display_name": "Management of Technology and Innovation"}, "field": {"id": "https://openalex.org/fields/14", "display_name": "Business, Management and Accounting"}, "domain": {"id": "https://openalex.org/domains/2", "display_name": "Social Sciences"}}, {"id": "https://openalex.org/T10041", "display_name": "COVID-19 Clinical Research Studies", "score": 0.983299970626831, "subfield": {"id": "https://openalex.org/subfields/2725", "display_name": "Infectious Diseases"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/adamts13", "display_name": "ADAMTS13", "score": 0.9531387090682983}, {"id": "https://openalex.org/keywords/von-willebrand-factor", "display_name": "Von Willebrand factor", "score": 0.8751263618469238}, {"id": "https://openalex.org/keywords/thrombotic-microangiopathy", "display_name": "Thrombotic microangiopathy", "score": 0.8707650899887085}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.7189454436302185}, {"id": "https://openalex.org/keywords/thrombotic-thrombocytopenic-purpura", "display_name": "Thrombotic thrombocytopenic purpura", "score": 0.646209716796875}, {"id": "https://openalex.org/keywords/coagulopathy", "display_name": "Coagulopathy", "score": 0.5540699362754822}, {"id": "https://openalex.org/keywords/intensive-care-unit", "display_name": "Intensive care unit", "score": 0.5225948095321655}, {"id": "https://openalex.org/keywords/thrombosis", "display_name": "Thrombosis", "score": 0.48587483167648315}, {"id": "https://openalex.org/keywords/platelet", "display_name": "Platelet", "score": 0.47355878353118896}, {"id": "https://openalex.org/keywords/immunology", "display_name": "Immunology", "score": 0.45552194118499756}, {"id": "https://openalex.org/keywords/adamts", "display_name": "ADAMTS", "score": 0.4388037621974945}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.43621155619621277}, {"id": "https://openalex.org/keywords/thrombospondin", "display_name": "Thrombospondin", "score": 0.38299769163131714}, {"id": "https://openalex.org/keywords/gastroenterology", "display_name": "Gastroenterology", "score": 0.35282260179519653}, {"id": "https://openalex.org/keywords/metalloproteinase", "display_name": "Metalloproteinase", "score": 0.15475109219551086}, {"id": "https://openalex.org/keywords/disease", "display_name": "Disease", "score": 0.10217827558517456}], "concepts": [{"id": "https://openalex.org/C2780921031", "wikidata": "https://www.wikidata.org/wiki/Q14873945", "display_name": "ADAMTS13", "level": 4, "score": 0.9531387090682983}, {"id": "https://openalex.org/C2779394231", "wikidata": "https://www.wikidata.org/wiki/Q412310", "display_name": "Von Willebrand factor", "level": 3, "score": 0.8751263618469238}, {"id": "https://openalex.org/C2777878052", "wikidata": "https://www.wikidata.org/wiki/Q3312044", "display_name": "Thrombotic microangiopathy", "level": 3, "score": 0.8707650899887085}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.7189454436302185}, {"id": "https://openalex.org/C2778585876", "wikidata": "https://www.wikidata.org/wiki/Q1426491", "display_name": "Thrombotic thrombocytopenic purpura", "level": 3, "score": 0.646209716796875}, {"id": "https://openalex.org/C2779936836", "wikidata": "https://www.wikidata.org/wiki/Q890200", "display_name": "Coagulopathy", "level": 2, "score": 0.5540699362754822}, {"id": "https://openalex.org/C2776376669", "wikidata": "https://www.wikidata.org/wiki/Q5094647", "display_name": "Intensive care unit", "level": 2, "score": 0.5225948095321655}, {"id": "https://openalex.org/C2780868729", "wikidata": "https://www.wikidata.org/wiki/Q261327", "display_name": "Thrombosis", "level": 2, "score": 0.48587483167648315}, {"id": "https://openalex.org/C89560881", "wikidata": "https://www.wikidata.org/wiki/Q101026", "display_name": "Platelet", "level": 2, "score": 0.47355878353118896}, {"id": "https://openalex.org/C203014093", "wikidata": "https://www.wikidata.org/wiki/Q101929", "display_name": "Immunology", "level": 1, "score": 0.45552194118499756}, {"id": "https://openalex.org/C2776224515", "wikidata": "https://www.wikidata.org/wiki/Q102253084", "display_name": "ADAMTS", "level": 5, "score": 0.4388037621974945}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.43621155619621277}, {"id": "https://openalex.org/C167814343", "wikidata": "https://www.wikidata.org/wiki/Q419341", "display_name": "Thrombospondin", "level": 4, "score": 0.38299769163131714}, {"id": "https://openalex.org/C90924648", "wikidata": "https://www.wikidata.org/wiki/Q120569", "display_name": "Gastroenterology", "level": 1, "score": 0.35282260179519653}, {"id": "https://openalex.org/C55728118", "wikidata": "https://www.wikidata.org/wiki/Q425402", "display_name": "Metalloproteinase", "level": 3, "score": 0.15475109219551086}, {"id": "https://openalex.org/C2779134260", "wikidata": "https://www.wikidata.org/wiki/Q12136", "display_name": "Disease", "level": 2, "score": 0.10217827558517456}, {"id": "https://openalex.org/C109523444", "wikidata": "https://www.wikidata.org/wiki/Q424216", "display_name": "Matrix metalloproteinase", "level": 2, "score": 0.0}], "mesh": [{"descriptor_ui": "D000071120", "descriptor_name": "ADAMTS13 Protein", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D000071120", "descriptor_name": "ADAMTS13 Protein", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D000071120", "descriptor_name": "ADAMTS13 Protein", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": "Q000503", "qualifier_name": "physiopathology", "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": "Q000503", "qualifier_name": "physiopathology", "is_major_topic": false}, {"descriptor_ui": "D000086382", "descriptor_name": "COVID-19", "qualifier_ui": "Q000503", "qualifier_name": "physiopathology", "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000368", "descriptor_name": "Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000369", "descriptor_name": "Aged, 80 and over", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000369", "descriptor_name": "Aged, 80 and over", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000369", "descriptor_name": "Aged, 80 and over", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013923", "descriptor_name": "Thromboembolism", "qualifier_ui": "Q000503", "qualifier_name": "physiopathology", "is_major_topic": false}, {"descriptor_ui": "D013923", "descriptor_name": "Thromboembolism", "qualifier_ui": "Q000503", "qualifier_name": "physiopathology", "is_major_topic": false}, {"descriptor_ui": "D013923", "descriptor_name": "Thromboembolism", "qualifier_ui": "Q000503", "qualifier_name": "physiopathology", "is_major_topic": false}, {"descriptor_ui": "D013923", "descriptor_name": "Thromboembolism", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D013923", "descriptor_name": "Thromboembolism", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D013923", "descriptor_name": "Thromboembolism", "qualifier_ui": "Q000821", "qualifier_name": "virology", "is_major_topic": false}, {"descriptor_ui": "D014841", "descriptor_name": "von Willebrand Factor", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D014841", "descriptor_name": "von Willebrand Factor", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}, {"descriptor_ui": "D014841", "descriptor_name": "von Willebrand Factor", "qualifier_ui": "Q000378", "qualifier_name": "metabolism", "is_major_topic": false}], "locations_count": 4, "locations": [{"id": "doi:10.1111/ijlh.13244", "is_oa": true, "landing_page_url": "https://doi.org/10.1111/ijlh.13244", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13244", "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, {"id": "pmid:32441844", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/32441844", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International journal of laboratory hematology", "raw_type": null}, {"id": "pmh:oai:dspace.library.uu.nl:1874/439842", "is_oa": true, "landing_page_url": "https://dspace.library.uu.nl/handle/1874/439842", "pdf_url": null, "source": {"id": "https://openalex.org/S4306401649", "display_name": "Utrecht University Repository (Utrecht University)", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I193662353", "host_organization_name": "Utrecht University", "host_organization_lineage": ["https://openalex.org/I193662353"], "host_organization_lineage_names": [], "type": "repository"}, "license": "other-oa", "license_id": "https://openalex.org/licenses/other-oa", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": null, "raw_type": "Letter"}, {"id": "pmh:oai:pubmedcentral.nih.gov:7280565", "is_oa": true, "landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/7280565", "pdf_url": null, "source": {"id": "https://openalex.org/S2764455111", "display_name": "PubMed Central", "issn_l": null, "issn": null, "is_oa": true, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "Int J Lab Hematol", "raw_type": "Text"}], "best_oa_location": {"id": "doi:10.1111/ijlh.13244", "is_oa": true, "landing_page_url": "https://doi.org/10.1111/ijlh.13244", "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13244", "source": {"id": "https://openalex.org/S66208518", "display_name": "International Journal of Laboratory Hematology", "issn_l": "1751-5521", "issn": ["1751-5521", "1751-553X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": "cc-by", "license_id": "https://openalex.org/licenses/cc-by", "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "International Journal of Laboratory Hematology", "raw_type": "journal-article"}, "sustainable_development_goals": [{"display_name": "Good health and well-being", "id": "https://metadata.un.org/sdg/3", "score": 0.8600000143051147}], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W3026179396.pdf", "grobid_xml": "https://content.openalex.org/works/W3026179396.grobid-xml"}, "referenced_works_count": 14, "referenced_works": ["https://openalex.org/W1969463403", "https://openalex.org/W2098106973", "https://openalex.org/W2154205460", "https://openalex.org/W2339962867", "https://openalex.org/W2619206214", "https://openalex.org/W2805098025", "https://openalex.org/W2805630869", "https://openalex.org/W2810019455", "https://openalex.org/W2888789033", "https://openalex.org/W2897799986", "https://openalex.org/W3003825348", "https://openalex.org/W3015863623", "https://openalex.org/W3015946392", "https://openalex.org/W3016764831"], "related_works": ["https://openalex.org/W3171162479", "https://openalex.org/W50398550", "https://openalex.org/W3030496443", "https://openalex.org/W17016037", "https://openalex.org/W2026002230", "https://openalex.org/W2077938696", "https://openalex.org/W2098937235", "https://openalex.org/W2782506322", "https://openalex.org/W2092127489", "https://openalex.org/W4251342322"], "abstract_inverted_index": {"Since": [0], "early": [1], "in": [2, 7, 32, 164, 205, 213, 224, 290, 298, 382, 408, 432, 438, 445, 458, 495, 533, 544], "2020,": [3, 22], "the": [4, 12, 17, 25, 43, 61, 85, 102, 206, 209, 246, 299, 433, 469, 503, 513, 516, 529, 545, 563, 568, 587, 592], "first": [5, 26], "people": [6], "Europe": [8], "were": [9, 296, 341, 361], "infected": [10, 56, 550], "with": [11, 28, 57, 118, 152, 215, 227, 410, 416, 441, 463, 551, 570], "SARS-CoV-2": [13, 30, 58, 216, 552], "virus": [14], "leading": [15, 155], "to": [16, 60, 156, 170, 175, 402, 488, 511, 528, 539, 591], "COVID-2019": [18], "pandemic.": [19], "In": [20, 390], "March": [21], "we": [23, 218, 483], "admitted": [24, 59], "patients": [27, 38, 55, 77, 214, 226, 287, 440, 460], "a": [29, 64, 79, 119, 172, 184, 228, 386, 554], "infection": [31], "our": [33, 489], "hospital.": [34], "Many": [35], "of": [36, 68, 101, 104, 114, 134, 141, 161, 187, 208, 231, 456, 468, 505, 518, 548], "these": [37, 286, 534], "eventually": [39], "end": [40], "up": [41], "at": [42, 82], "intensive": [44], "care": [45], "unit": [46], "(ICU).": [47], "We": [48, 536], "and": [49, 74, 87, 106, 200, 221, 330, 358, 394, 425, 449, 479, 522, 542, 560, 576, 589], "others": [50], "have": [51, 63, 78, 171, 580], "previously": [52, 411], "reported": [53], "that": [54], "ICU": [62, 86], "strikingly": [65], "high": [66, 264, 523], "rate": [67], "thromboembolic": [69, 210], "complications": [70, 211], "ranging": [71], "between": [72, 420, 474], "25%": [73], "35%.1-3": [75], "These": [76, 405], "hypercoagulable": [80], "state": [81, 531, 556], "admission": [83], "on": [84, 363, 374, 481], "show": [88, 385], "mainly": [89], "renal": [90], "impairment": [91], "as": [92, 443], "second": [93], "organ": [94], "involvement.": [95], "Thrombotic": [96], "microangiopathy": [97, 232], "(TMA)": [98], "is": [99, 182, 500, 557], "one": [100], "consequences": [103], "sepsis": [105, 439, 459], "may": [107], "be": [108, 429, 493], "caused": [109], "by": [110, 190, 245], "greatly": [111], "reduced": [112, 132], "levels": [113, 133, 223, 393, 397, 455, 525], "\u201ca": [115], "disintegrin-like": [116], "metalloprotease": [117], "thrombospondin": [120], "type": [121], "1": [122, 260, 271, 279], "motif,": [123], "member": [124], "13\u201d": [125], "(ADAMTS13,": [126], "von": [127, 143], "Willebrand": [128, 144], "cleaving": [129], "protease).": [130], "Severely": [131], "ADAMTS13": [135, 162, 199, 220, 359, 388, 457, 506, 520, 541], "(usually": [136], "<": [137], "10%)": [138], "cause": [139], "accumulation": [140], "ultralarge": [142], "factor": [145, 316, 320, 395], "(vWF)": [146], "multimers,": [147], "which": [148], "can": [149, 492], "interact": [150], "spontaneously": [151], "platelets,": [153], "ultimately": [154], "microvascular": [157], "thrombosis.4": [158], "The": [159, 380, 418, 578], "decrease": [160], "activity": [163, 356, 360, 507, 521], "consumptive": [165], "coagulopathy": [166], "has": [167], "been": [168], "shown": [169, 289], "stronger": [173], "relationship": [174], "platelet": [176], "dynamics": [177], "even": [178], "before": [179], "thrombocytopenia.5": [180], "There": [181], "also": [183, 484], "probable": [185], "risk": [186, 480], "thrombosis": [188], "induced": [189], "inflammation": [191], "via": [192], "vWF-platelet": [193], "axis.6,": [194], "7": [195], "To": [196], "clarify": [197], "whether": [198], "vWF": [201, 222, 351, 353, 392, 475, 524, 543], "are": [202, 288, 398, 407, 461], "indeed": [203], "involved": [204], "pathophysiology": [207], "seen": [212, 437, 444, 494], "infection,": [217], "measured": [219, 297, 342, 362, 373], "12": [225], "clinical": [229], "suspicion": [230], "(Table": [233], "1).": [234], "A": [235], "formal": [236], "ethics": [237], "review": [238], "for": [239, 285], "this": [240, 486, 498], "study": [241], "was": [242, 372, 508], "deemed": [243], "unnecessary": [244], "local": [247], "Ethics": [248], "Committee.": [249], "6": [250], "Patients:": [251, 277], "LMWH": [252, 262], "(dalteparin),": [253, 263], "prophylactic": [254, 265], "dose": [255, 266, 275], "(1": [256], "dd": [257, 268], "5000": [258, 269], "IU)": [259, 270], "Patient:": [261, 272, 280], "(2": [267], "LMWH:": [273], "therapeutic": [274], "3": [276], "UFH": [278], "Arterial": [281], "Thrombolysis": [282], "Laboratory": [283], "results": [284, 413, 588], "Table": [291, 383, 496], "2.": [292], "All": [293, 584], "laboratory": [294, 303], "assays": [295], "central": [300], "ISO-15189": [301], "accredited": [302], "using": [304, 314, 343], "an": [305, 344, 364, 375, 472], "ACL": [306], "Top": [307], "750": [308], "LAS": [309], "coagulation": [310, 435, 448], "analyzer": [311, 348, 367, 378], "(Werfen": [312], "Diagnostics)": [313], "Coamatic": [315], "VIII": [317, 396], "reagent": [318, 324, 328, 333], "(chromogenic": [319], "VIII),": [321], "QFA": [322], "Thrombin": [323], "(fibrinogen),": [325], "liquid": [326], "antithrombin": [327], "(antithrombin),": [329], "D-dimer": [331], "HS500": [332], "(D-dimer)": [334], "all": [335], "obtained": [336], "from": [337, 414, 572], "Werfen": [338], "diagnostics.": [339], "Platelets": [340], "Alinity": [345], "Hq": [346], "hematology": [347], "(Abbott": [349], "Diagnostics).": [350], "antigen,": [352], "ristocetin": [354], "cofactor": [355], "(VWF:GPIbR),": [357], "ACUstar": [365], "chemiluminescence": [366], "(Werfen);": [368], "plasma": [369, 454], "creatinine": [370], "concentration": [371], "Atellica": [376], "chemistry": [377], "(Siemens).": [379], "data": [381, 406], "2": [384], "low": [387, 519], "activity.": [389], "contrast,": [391], "increased,": [399], "probably": [400], "due": [401], "activated": [403], "endothelium.8": [404], "accordance": [409], "described": [412], "patient": [415, 549], "sepsis.9": [417], "interaction": [419], "injured": [421], "vessel": [422], "wall,": [423], "vWF,": [424], "ADAMTS": [426], "13": [427, 466], "might": [428, 526], "potentially": [430], "relevant": [431], "pathophysiological": [434], "changes": [436], "microthrombosis": [442], "disseminated": [446], "intravascular": [447], "microangiopathy.4,": [450], "10,": [451], "11": [452], "Low": [453], "associated": [462], "worse": [464], "outcome.12,": [465], "Because": [467], "evidence": [470], "indicating": [471], "association": [473], "antigen:": [476], "ADAMT13": [477], "ratio": [478, 487, 499], "thrombosis,": [482], "included": [485], "measurements.14": [490], "As": [491], "1,": [497], "high.": [501], "Although": [502], "level": [504], "not": [509], "conclusive": [510], "confirm": [512], "microangiopathic": [514, 530, 555], "state,": [515], "combination": [517], "contribute": [527], "observed": [532], "patients.": [535], "therefore": [537], "suggest": [538], "include": [540], "diagnostic": [546], "workup": [547], "when": [553], "suspected.": [558], "AH": [559, 566], "NK": [561], "conceived": [562], "presented": [564], "concept.": [565], "wrote": [567], "manuscript": [569], "support": [571], "RB,": [573], "MS,": [574], "JW,": [575], "NK.": [577], "authors": [579, 585], "no": [581], "competing": [582], "interests.": [583], "discussed": [586], "contributed": [590], "final": [593], "manuscript.": [594]}, "counts_by_year": [{"year": 2025, "cited_by_count": 2}, {"year": 2024, "cited_by_count": 1}, {"year": 2023, "cited_by_count": 10}, {"year": 2022, "cited_by_count": 13}, {"year": 2021, "cited_by_count": 25}, {"year": 2020, "cited_by_count": 23}], "updated_date": "2025-11-06T03:46:38.306776", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W178133169", "doi": "https://doi.org/10.1093/ajcp/100.2.123", "title": "An Evaluation of Hemoglobin Determination Using Sodium Lauryl Sulfate", "display_name": "An Evaluation of Hemoglobin Determination Using Sodium Lauryl Sulfate", "relevance_score": 48.46021, "publication_year": 1993, "publication_date": "1993-08-01", "ids": {"openalex": "https://openalex.org/W178133169", "doi": "https://doi.org/10.1093/ajcp/100.2.123", "mag": "178133169", "pmid": "https://pubmed.ncbi.nlm.nih.gov/8356944"}, "language": "en", "primary_location": {"id": "doi:10.1093/ajcp/100.2.123", "is_oa": false, "landing_page_url": "https://doi.org/10.1093/ajcp/100.2.123", "pdf_url": null, "source": {"id": "https://openalex.org/S15871148", "display_name": "American Journal of Clinical Pathology", "issn_l": "0002-9173", "issn": ["0002-9173", "1943-7722"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310311648", "host_organization_name": "Oxford University Press", "host_organization_lineage": ["https://openalex.org/P4310311648", "https://openalex.org/P4310311647"], "host_organization_lineage_names": ["Oxford University Press", "University of Oxford"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Clinical Pathology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5083812935", "display_name": "Aly Karsan", "orcid": "https://orcid.org/0000-0001-6753-892X"}, "institutions": [{"id": "https://openalex.org/I4210153200", "display_name": "British Columbia Children's Hospital", "ror": "https://ror.org/04n901w50", "country_code": "CA", "type": "healthcare", "lineage": ["https://openalex.org/I4210153200"]}], "countries": ["CA"], "is_corresponding": true, "raw_author_name": "Aly Karsan", "raw_affiliation_strings": ["Department of Pathology, British Columbia Children's Hospital, Vancouver, Canada", "Department of Pathology, British Columbia Children's Hospital, Vancouver Canada"], "affiliations": [{"raw_affiliation_string": "Department of Pathology, British Columbia Children's Hospital, Vancouver, Canada", "institution_ids": ["https://openalex.org/I4210153200"]}, {"raw_affiliation_string": "Department of Pathology, British Columbia Children's Hospital, Vancouver Canada", "institution_ids": ["https://openalex.org/I4210153200"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5084945407", "display_name": "Ian MacLaren", "orcid": "https://orcid.org/0000-0002-5334-3010"}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Ian Maclaren", "raw_affiliation_strings": ["From the Department of Pathology, British Columbia Children\u2019s Hospital & the University of British Columbia, Vancouver, British Columbia, Canada"], "affiliations": [{"raw_affiliation_string": "From the Department of Pathology, British Columbia Children\u2019s Hospital & the University of British Columbia, Vancouver, British Columbia, Canada", "institution_ids": []}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5064524199", "display_name": "Debbie Conn", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Debbie Conn", "raw_affiliation_strings": ["From the Department of Pathology, British Columbia Children\u2019s Hospital & the University of British Columbia, Vancouver, British Columbia, Canada"], "affiliations": [{"raw_affiliation_string": "From the Department of Pathology, British Columbia Children\u2019s Hospital & the University of British Columbia, Vancouver, British Columbia, Canada", "institution_ids": []}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5109424773", "display_name": "Louis D. Wadsworth", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Louis Wadsworth", "raw_affiliation_strings": ["From the Department of Pathology, British Columbia Children\u2019s Hospital & the University of British Columbia, Vancouver, British Columbia, Canada"], "affiliations": [{"raw_affiliation_string": "From the Department of Pathology, British Columbia Children\u2019s Hospital & the University of British Columbia, Vancouver, British Columbia, Canada", "institution_ids": []}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 4, "corresponding_author_ids": ["https://openalex.org/A5083812935"], "corresponding_institution_ids": ["https://openalex.org/I4210153200"], "apc_list": {"value": 4440, "currency": "USD", "value_usd": 4440}, "apc_paid": null, "fwci": 0.5452, "has_fulltext": false, "cited_by_count": 38, "citation_normalized_percentile": {"value": 0.70105578, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 99}, "biblio": {"volume": "100", "issue": "2", "first_page": "123", "last_page": "126"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T12305", "display_name": "Cassava research and cyanide", "score": 0.9553999900817871, "subfield": {"id": "https://openalex.org/subfields/1110", "display_name": "Plant Science"}, "field": {"id": "https://openalex.org/fields/11", "display_name": "Agricultural and Biological Sciences"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, "topics": [{"id": "https://openalex.org/T12305", "display_name": "Cassava research and cyanide", "score": 0.9553999900817871, "subfield": {"id": "https://openalex.org/subfields/1110", "display_name": "Plant Science"}, "field": {"id": "https://openalex.org/fields/11", "display_name": "Agricultural and Biological Sciences"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T10875", "display_name": "Pesticide Exposure and Toxicity", "score": 0.9085999727249146, "subfield": {"id": "https://openalex.org/subfields/1110", "display_name": "Plant Science"}, "field": {"id": "https://openalex.org/fields/11", "display_name": "Agricultural and Biological Sciences"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hemoglobin", "display_name": "Hemoglobin", "score": 0.8057956695556641}, {"id": "https://openalex.org/keywords/reagent", "display_name": "Reagent", "score": 0.721198558807373}, {"id": "https://openalex.org/keywords/chemistry", "display_name": "Chemistry", "score": 0.6600692272186279}, {"id": "https://openalex.org/keywords/cyanide", "display_name": "Cyanide", "score": 0.6535180807113647}, {"id": "https://openalex.org/keywords/chromatography", "display_name": "Chromatography", "score": 0.6509670615196228}, {"id": "https://openalex.org/keywords/sulfate", "display_name": "Sulfate", "score": 0.5949500799179077}, {"id": "https://openalex.org/keywords/sodium", "display_name": "Sodium", "score": 0.4882645606994629}, {"id": "https://openalex.org/keywords/biochemistry", "display_name": "Biochemistry", "score": 0.21032977104187012}, {"id": "https://openalex.org/keywords/inorganic-chemistry", "display_name": "Inorganic chemistry", "score": 0.13591426610946655}, {"id": "https://openalex.org/keywords/organic-chemistry", "display_name": "Organic chemistry", "score": 0.06770795583724976}], "concepts": [{"id": "https://openalex.org/C2778917026", "wikidata": "https://www.wikidata.org/wiki/Q43041", "display_name": "Hemoglobin", "level": 2, "score": 0.8057956695556641}, {"id": "https://openalex.org/C40875361", "wikidata": "https://www.wikidata.org/wiki/Q2356542", "display_name": "Reagent", "level": 2, "score": 0.721198558807373}, {"id": "https://openalex.org/C185592680", "wikidata": "https://www.wikidata.org/wiki/Q2329", "display_name": "Chemistry", "level": 0, "score": 0.6600692272186279}, {"id": "https://openalex.org/C2778455166", "wikidata": "https://www.wikidata.org/wiki/Q55076544", "display_name": "Cyanide", "level": 2, "score": 0.6535180807113647}, {"id": "https://openalex.org/C43617362", "wikidata": "https://www.wikidata.org/wiki/Q170050", "display_name": "Chromatography", "level": 1, "score": 0.6509670615196228}, {"id": "https://openalex.org/C2778343803", "wikidata": "https://www.wikidata.org/wiki/Q172290", "display_name": "Sulfate", "level": 2, "score": 0.5949500799179077}, {"id": "https://openalex.org/C537181965", "wikidata": "https://www.wikidata.org/wiki/Q658", "display_name": "Sodium", "level": 2, "score": 0.4882645606994629}, {"id": "https://openalex.org/C55493867", "wikidata": "https://www.wikidata.org/wiki/Q7094", "display_name": "Biochemistry", "level": 1, "score": 0.21032977104187012}, {"id": "https://openalex.org/C179104552", "wikidata": "https://www.wikidata.org/wiki/Q11165", "display_name": "Inorganic chemistry", "level": 1, "score": 0.13591426610946655}, {"id": "https://openalex.org/C178790620", "wikidata": "https://www.wikidata.org/wiki/Q11351", "display_name": "Organic chemistry", "level": 1, "score": 0.06770795583724976}], "mesh": [{"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005069", "descriptor_name": "Evaluation Studies as Topic", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006452", "descriptor_name": "Hemoglobinometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D006452", "descriptor_name": "Hemoglobinometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D006452", "descriptor_name": "Hemoglobinometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D006454", "descriptor_name": "Hemoglobins", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006454", "descriptor_name": "Hemoglobins", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006454", "descriptor_name": "Hemoglobins", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008706", "descriptor_name": "Methemoglobin", "qualifier_ui": "Q000031", "qualifier_name": "analogs & derivatives", "is_major_topic": false}, {"descriptor_ui": "D008706", "descriptor_name": "Methemoglobin", "qualifier_ui": "Q000031", "qualifier_name": "analogs & derivatives", "is_major_topic": false}, {"descriptor_ui": "D008706", "descriptor_name": "Methemoglobin", "qualifier_ui": "Q000031", "qualifier_name": "analogs & derivatives", "is_major_topic": false}, {"descriptor_ui": "D012967", "descriptor_name": "Sodium Dodecyl Sulfate", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D012967", "descriptor_name": "Sodium Dodecyl Sulfate", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D012967", "descriptor_name": "Sodium Dodecyl Sulfate", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}], "locations_count": 2, "locations": [{"id": "doi:10.1093/ajcp/100.2.123", "is_oa": false, "landing_page_url": "https://doi.org/10.1093/ajcp/100.2.123", "pdf_url": null, "source": {"id": "https://openalex.org/S15871148", "display_name": "American Journal of Clinical Pathology", "issn_l": "0002-9173", "issn": ["0002-9173", "1943-7722"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310311648", "host_organization_name": "Oxford University Press", "host_organization_lineage": ["https://openalex.org/P4310311648", "https://openalex.org/P4310311647"], "host_organization_lineage_names": ["Oxford University Press", "University of Oxford"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American Journal of Clinical Pathology", "raw_type": "journal-article"}, {"id": "pmid:8356944", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/8356944", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "American journal of clinical pathology", "raw_type": null}], "best_oa_location": null, "sustainable_development_goals": [{"display_name": "Clean water and sanitation", "id": "https://metadata.un.org/sdg/6", "score": 0.6000000238418579}], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 5, "referenced_works": ["https://openalex.org/W2030460646", "https://openalex.org/W2035756871", "https://openalex.org/W2065333546", "https://openalex.org/W2095870992", "https://openalex.org/W2296648895"], "related_works": ["https://openalex.org/W2952256733", "https://openalex.org/W2952556931", "https://openalex.org/W2145535646", "https://openalex.org/W1970587968", "https://openalex.org/W2950613640", "https://openalex.org/W2952573305", "https://openalex.org/W2949460484", "https://openalex.org/W2951174005", "https://openalex.org/W2362172668", "https://openalex.org/W2353295573"], "abstract_inverted_index": {"The": [0, 59], "standard": [1], "reference": [2], "method": [3, 35, 64, 68, 110, 122], "for": [4, 7], "hemoglobin": [5, 39, 113], "determination": [6], "years": [8], "has": [9, 48], "been": [10, 49], "the": [11, 38, 66, 82, 93, 106, 120, 125], "photometric": [12], "quantitation": [13], "of": [14, 92, 111, 127], "cyanmethemoglobin.": [15], "Other": [16], "existing": [17], "methods": [18, 84], "have": [19], "not": [20], "gained": [21], "popularity": [22], "in": [23, 41], "North": [24], "America.": [25], "In": [26, 88], "an": [27, 116], "attempt": [28], "to": [29, 36, 119], "eliminate": [30], "hazardous": [31], "cyanide": [32], "waste,": [33], "a": [34, 56], "determine": [37], "concentration": [40, 114], "whole": [42], "blood": [43, 95], "using": [44, 69], "sodium": [45, 107], "lauryl": [46, 108], "sulfate": [47, 109], "devised": [50], "and": [51, 123], "recently": [52], "was": [53, 103], "released": [54], "as": [55], "commercial": [57], "reagent.": [58], "authors": [60], "compare": [61], "this": [62], "new": [63], "with": [65], "cyanmethemoglobin": [67, 121], "two": [70, 83], "hematology": [71], "analyzers.": [72], "Their": [73], "results": [74], "show": [75, 98], "that": [76, 105], "there": [77], "is": [78, 115], "excellent": [79], "correlation": [80], "between": [81], "(r2": [85], "=": [86], "0.996).": [87], "addition,": [89], "other": [90], "elements": [91], "complete": [94], "count": [96], "also": [97], "good": [99], "correlation.": [100], "Thus,": [101], "it": [102], "confirmed": [104], "estimating": [112], "appropriate": [117], "alternative": [118], "avoids": [124], "generation": [126], "toxic": [128], "wastes.": [129]}, "counts_by_year": [{"year": 2025, "cited_by_count": 4}, {"year": 2024, "cited_by_count": 3}, {"year": 2022, "cited_by_count": 3}, {"year": 2021, "cited_by_count": 6}, {"year": 2020, "cited_by_count": 8}, {"year": 2019, "cited_by_count": 2}, {"year": 2017, "cited_by_count": 1}, {"year": 2016, "cited_by_count": 2}, {"year": 2013, "cited_by_count": 1}, {"year": 2012, "cited_by_count": 1}], "updated_date": "2026-01-13T01:12:25.745995", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W2043021543", "doi": "https://doi.org/10.1111/j.1939-165x.2002.tb00286.x", "title": "Artifactual Changes in Equine Blood Following Storage, Detected Using the Advia 120 Hematology Analyzer", "display_name": "Artifactual Changes in Equine Blood Following Storage, Detected Using the Advia 120 Hematology Analyzer", "relevance_score": 46.68451, "publication_year": 2002, "publication_date": "2002-06-01", "ids": {"openalex": "https://openalex.org/W2043021543", "doi": "https://doi.org/10.1111/j.1939-165x.2002.tb00286.x", "mag": "2043021543", "pmid": "https://pubmed.ncbi.nlm.nih.gov/12040491"}, "language": "en", "primary_location": {"id": "doi:10.1111/j.1939-165x.2002.tb00286.x", "is_oa": false, "landing_page_url": "https://doi.org/10.1111/j.1939-165x.2002.tb00286.x", "pdf_url": null, "source": {"id": "https://openalex.org/S113475689", "display_name": "Veterinary Clinical Pathology", "issn_l": "0275-6382", "issn": ["0275-6382", "1939-165X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Veterinary Clinical Pathology", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5006381884", "display_name": "P. Clark", "orcid": "https://orcid.org/0000-0001-6769-4957"}, "institutions": [{"id": "https://openalex.org/I51158804", "display_name": "Massey University", "ror": "https://ror.org/052czxv31", "country_code": "NZ", "type": "education", "lineage": ["https://openalex.org/I51158804"]}], "countries": ["NZ"], "is_corresponding": true, "raw_author_name": "Phillip Clark", "raw_affiliation_strings": ["Pathobiology Section, Institute of Veterinary, Animal, and Biochemical Sciences, Massey University, Palmerston North, New Zealand. pclark@murdoch.edu.au", "Pathobiology Section, Institute of Veterinary, Animal, and Biochemical Sciences, Massey University, Palmerston North, New Zealand"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Pathobiology Section, Institute of Veterinary, Animal, and Biochemical Sciences, Massey University, Palmerston North, New Zealand. pclark@murdoch.edu.au", "institution_ids": ["https://openalex.org/I51158804"]}, {"raw_affiliation_string": "Pathobiology Section, Institute of Veterinary, Animal, and Biochemical Sciences, Massey University, Palmerston North, New Zealand", "institution_ids": ["https://openalex.org/I51158804"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5111792673", "display_name": "Tony D. Mogg", "orcid": null}, "institutions": [{"id": "https://openalex.org/I51158804", "display_name": "Massey University", "ror": "https://ror.org/052czxv31", "country_code": "NZ", "type": "education", "lineage": ["https://openalex.org/I51158804"]}], "countries": ["NZ"], "is_corresponding": false, "raw_author_name": "Tony D. Mogg", "raw_affiliation_strings": ["Massey Equine, Institute of Veterinary, Animal, and Biochemical Sciences, Massey University, Palmerston North, New Zealand"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Massey Equine, Institute of Veterinary, Animal, and Biochemical Sciences, Massey University, Palmerston North, New Zealand", "institution_ids": ["https://openalex.org/I51158804"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5061051950", "display_name": "Harold Tvedten", "orcid": "https://orcid.org/0000-0003-4066-7662"}, "institutions": [{"id": "https://openalex.org/I298625061", "display_name": "Swedish University of Agricultural Sciences", "ror": "https://ror.org/02yy8x990", "country_code": "SE", "type": "education", "lineage": ["https://openalex.org/I298625061"]}], "countries": ["SE"], "is_corresponding": false, "raw_author_name": "Harold W. Tvedten", "raw_affiliation_strings": ["Department of Clinical Chemistry, Faculty of Veterinary Medicine, Swedish Agricultural University, Uppsala, Sweden"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Clinical Chemistry, Faculty of Veterinary Medicine, Swedish Agricultural University, Uppsala, Sweden", "institution_ids": ["https://openalex.org/I298625061"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5037688143", "display_name": "David Korcal", "orcid": null}, "institutions": [{"id": "https://openalex.org/I87216513", "display_name": "Michigan State University", "ror": "https://ror.org/05hs6h993", "country_code": "US", "type": "education", "lineage": ["https://openalex.org/I87216513"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "David Korcal", "raw_affiliation_strings": ["Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, East Lansing, Mich"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, East Lansing, Mich", "institution_ids": ["https://openalex.org/I87216513"]}]}], "institutions": [], "countries_distinct_count": 3, "institutions_distinct_count": 4, "corresponding_author_ids": ["https://openalex.org/A5006381884"], "corresponding_institution_ids": ["https://openalex.org/I51158804"], "apc_list": {"value": 3240, "currency": "USD", "value_usd": 3240}, "apc_paid": null, "fwci": 0.1572, "has_fulltext": false, "cited_by_count": 55, "citation_normalized_percentile": {"value": 0.5116896, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 90, "max": 99}, "biblio": {"volume": "31", "issue": "2", "first_page": "90", "last_page": "94"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9921000003814697, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9921000003814697, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T10693", "display_name": "Blood transfusion and management", "score": 0.00139999995008111, "subfield": {"id": "https://openalex.org/subfields/2704", "display_name": "Biochemistry"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.0013000000035390258, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.9720638990402222}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.751953125}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.5511863827705383}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.5362682938575745}, {"id": "https://openalex.org/keywords/pathology", "display_name": "Pathology", "score": 0.32468608021736145}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.9720638990402222}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.751953125}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.5511863827705383}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.5362682938575745}, {"id": "https://openalex.org/C142724271", "wikidata": "https://www.wikidata.org/wiki/Q7208", "display_name": "Pathology", "level": 1, "score": 0.32468608021736145}], "mesh": [{"descriptor_ui": "D000818", "descriptor_name": "Animals", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000818", "descriptor_name": "Animals", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000818", "descriptor_name": "Animals", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000662", "qualifier_name": "veterinary", "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000662", "qualifier_name": "veterinary", "is_major_topic": false}, {"descriptor_ui": "D001793", "descriptor_name": "Blood Preservation", "qualifier_ui": "Q000662", "qualifier_name": "veterinary", "is_major_topic": false}, {"descriptor_ui": "D004907", "descriptor_name": "Erythrocyte Deformability", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D004907", "descriptor_name": "Erythrocyte Deformability", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D004907", "descriptor_name": "Erythrocyte Deformability", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000502", "qualifier_name": "physiology", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000502", "qualifier_name": "physiology", "is_major_topic": false}, {"descriptor_ui": "D004912", "descriptor_name": "Erythrocytes", "qualifier_ui": "Q000502", "qualifier_name": "physiology", "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000662", "qualifier_name": "veterinary", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000662", "qualifier_name": "veterinary", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000662", "qualifier_name": "veterinary", "is_major_topic": false}, {"descriptor_ui": "D006736", "descriptor_name": "Horses", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D006736", "descriptor_name": "Horses", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D006736", "descriptor_name": "Horses", "qualifier_ui": "Q000097", "qualifier_name": "blood", "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013696", "descriptor_name": "Temperature", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013696", "descriptor_name": "Temperature", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013696", "descriptor_name": "Temperature", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013997", "descriptor_name": "Time Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013997", "descriptor_name": "Time Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013997", "descriptor_name": "Time Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016477", "descriptor_name": "Artifacts", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D016477", "descriptor_name": "Artifacts", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D016477", "descriptor_name": "Artifacts", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}], "locations_count": 3, "locations": [{"id": "doi:10.1111/j.1939-165x.2002.tb00286.x", "is_oa": false, "landing_page_url": "https://doi.org/10.1111/j.1939-165x.2002.tb00286.x", "pdf_url": null, "source": {"id": "https://openalex.org/S113475689", "display_name": "Veterinary Clinical Pathology", "issn_l": "0275-6382", "issn": ["0275-6382", "1939-165X"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Veterinary Clinical Pathology", "raw_type": "journal-article"}, {"id": "pmid:12040491", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/12040491", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Veterinary clinical pathology", "raw_type": null}, {"id": "pmh:oai:researchrepository.murdoch.edu.au:16860", "is_oa": false, "landing_page_url": "http://researchrepository.murdoch.edu.au/id/eprint/16860/", "pdf_url": null, "source": {"id": "https://openalex.org/S4306400274", "display_name": "Murdoch Research Repository (Murdoch University)", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I176790772", "host_organization_name": "Murdoch University", "host_organization_lineage": ["https://openalex.org/I176790772"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "  Clark, P. &lt;http://researchrepository.murdoch.edu.au/view/author/Clark, Phillip.html&gt;, Mogg, T.D., Tvedten, H.W. and Korcal, D.   (2002) Artifactual changes in equine blood following storage, detected using the Advia 120 hematology analyzer.   Veterinary Clinical Pathology, 31  (2).   pp. 90-94.  ", "raw_type": "Journal Article"}], "best_oa_location": null, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 6, "referenced_works": ["https://openalex.org/W38494535", "https://openalex.org/W1593136742", "https://openalex.org/W1966492531", "https://openalex.org/W2086120967", "https://openalex.org/W2121787596", "https://openalex.org/W2334470538"], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W3114788508", "https://openalex.org/W2352314160", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W1601719760", "https://openalex.org/W2359341290", "https://openalex.org/W2034944612"], "abstract_inverted_index": {"BACKGROUND:": [0], "Delayed": [1, 98], "analysis": [2, 27, 99], "of": [3, 25, 32, 38, 60, 81, 100, 108, 114, 119, 134, 148, 152, 173], "blood": [4, 61, 102, 179], "samples": [5, 103, 187], "may": [6, 16, 29], "be": [7], "caused": [8], "by": [9, 144, 158, 167], "restricted": [10], "access": [11], "to": [12, 42, 50, 132], "laboratories.": [13], "Artifactual": [14], "changes": [15, 45, 155, 163, 175, 182], "occur": [17], "in": [18, 46, 105, 164, 176, 186], "the": [19, 33, 53, 68, 125, 149, 153, 168], "measured": [20], "analytes": [21], "as": [22, 121, 137], "a": [23], "consequence": [24], "delayed": [26], "and": [28, 74, 78, 129], "complicate": [30], "interpretation": [31], "data.": [34], "OBJECTIVE:": [35], "The": [36, 139], "purpose": [37], "this": [39], "study": [40], "was": [41, 142], "characterize": [43], "artifactual": [44, 154, 174], "equine": [47, 101, 178], "blood,": [48], "due": [49, 131], "storage,": [51], "using": [52, 67, 124], "Advia": [54, 69, 169], "120": [55, 70, 170], "hematology": [56], "analyzer.": [57], "METHODS:": [58], "Samples": [59], "from": [62], "5": [63], "horses": [64], "were": [65, 156, 183], "analyzed": [66], "soon": [71], "after": [72, 76], "collection": [73], "again": [75], "24": [77, 94, 190], "48": [79], "hours": [80], "storage": [82], "at": [83, 189, 194], "either": [84], "4": [85, 195], "degrees": [86, 95, 191, 196], "C": [87, 192], "or": [88], "ambient": [89], "laboratory": [90], "temperature": [91], "(": [92], "approximately": [93], "C).": [96], "RESULTS:": [97], "resulted": [104], "increased": [106, 112], "numbers": [107, 113], "normocytic": [109], "hypochromic": [110, 116], "RBCs,": [111, 117], "macrocytic": [115], "misclassification": [118, 133], "granulocytes": [120], "mononuclear": [122], "cells": [123], "basophil": [126], "reagent": [127], "method,": [128], "pseudothrombocytosis,": [130], "ghost": [135], "RBCs": [136], "platelets.": [138], "latter": [140], "artifact": [141], "corrected": [143], "an": [145], "amended": [146], "version": [147], "software.": [150], "Many": [151], "identified": [157], "morphology": [159], "flags.": [160], "CONCLUSIONS:": [161], "Characteristic": [162], "cytograms": [165], "produced": [166], "allowed": [171], "recognition": [172], "stored": [177, 188], "samples.": [180], "These": [181], "less": [184], "pronounced": [185], "than": [193], "C.": [197]}, "counts_by_year": [{"year": 2026, "cited_by_count": 1}, {"year": 2025, "cited_by_count": 1}, {"year": 2024, "cited_by_count": 1}, {"year": 2022, "cited_by_count": 4}, {"year": 2020, "cited_by_count": 4}, {"year": 2019, "cited_by_count": 4}, {"year": 2018, "cited_by_count": 4}, {"year": 2017, "cited_by_count": 3}, {"year": 2016, "cited_by_count": 1}, {"year": 2015, "cited_by_count": 4}, {"year": 2014, "cited_by_count": 6}, {"year": 2013, "cited_by_count": 1}, {"year": 2012, "cited_by_count": 5}], "updated_date": "2026-04-29T09:16:38.111599", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W1978753784", "doi": "https://doi.org/10.4103/0019-5359.42725", "title": "Reference ranges for lymphocyte subsets in adults from western India: Influence of sex, age and method of enumeration", "display_name": "Reference ranges for lymphocyte subsets in adults from western India: Influence of sex, age and method of enumeration", "relevance_score": 45.206417, "publication_year": 2008, "publication_date": "2008-01-01", "ids": {"openalex": "https://openalex.org/W1978753784", "doi": "https://doi.org/10.4103/0019-5359.42725", "mag": "1978753784", "pmid": "https://pubmed.ncbi.nlm.nih.gov/19008613"}, "language": "en", "primary_location": {"id": "doi:10.4103/0019-5359.42725", "is_oa": false, "landing_page_url": "https://doi.org/10.4103/0019-5359.42725", "pdf_url": null, "source": {"id": "https://openalex.org/S122944797", "display_name": "Indian Journal of Medical Sciences", "issn_l": "0019-5359", "issn": ["0019-5359", "1998-3654"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320448", "host_organization_name": "Medknow", "host_organization_lineage": ["https://openalex.org/P4310320448", "https://openalex.org/P4310318547"], "host_organization_lineage_names": ["Medknow", "Wolters Kluwer"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Indian Journal of Medical Sciences", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "green", "oa_url": "https://utoronto.scholaris.ca/bitstreams/02e9e483-558a-43a8-9222-eb3c4fffafa4/download", "any_repository_has_fulltext": true}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5111685758", "display_name": "BibhuR Das", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": true, "raw_author_name": "BibhuR Das", "raw_affiliation_strings": ["Research and Development, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Research and Development, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India", "institution_ids": []}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5113535022", "display_name": "AparnaA Bhanushali", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "AparnaA Bhanushali", "raw_affiliation_strings": ["Research and Development, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Research and Development, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India", "institution_ids": []}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5076745944", "display_name": "Rashmi Khadapkar", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "R Khadapkar", "raw_affiliation_strings": ["Research and Development, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Research and Development, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India", "institution_ids": []}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5081881180", "display_name": "KanchanD Jeswani", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "KanchanD Jeswani", "raw_affiliation_strings": ["Department of Hematology, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Hematology, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India", "institution_ids": []}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5081431019", "display_name": "Mita Bhavsar", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "Mita Bhavsar", "raw_affiliation_strings": ["Department of Hematology, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Hematology, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India", "institution_ids": []}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5111857323", "display_name": "A. K. Dasgupta", "orcid": null}, "institutions": [], "countries": [], "is_corresponding": false, "raw_author_name": "A Dasgupta", "raw_affiliation_strings": ["Department of Hematology, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "Department of Hematology, SRL Ranbaxy Ltd, Plot No 113, MIDC,15th Street, Andheri (East), Mumbai-400 093, India", "institution_ids": []}]}], "institutions": [], "countries_distinct_count": 0, "institutions_distinct_count": 6, "corresponding_author_ids": ["https://openalex.org/A5111685758"], "corresponding_institution_ids": [], "apc_list": null, "apc_paid": null, "fwci": 0.9945, "has_fulltext": true, "cited_by_count": 47, "citation_normalized_percentile": {"value": 0.72292301, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 90, "max": 99}, "biblio": {"volume": "62", "issue": "10", "first_page": "397", "last_page": "397"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T10112", "display_name": "HIV Research and Treatment", "score": 0.3402999937534332, "subfield": {"id": "https://openalex.org/subfields/2406", "display_name": "Virology"}, "field": {"id": "https://openalex.org/fields/24", "display_name": "Immunology and Microbiology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, "topics": [{"id": "https://openalex.org/T10112", "display_name": "HIV Research and Treatment", "score": 0.3402999937534332, "subfield": {"id": "https://openalex.org/subfields/2406", "display_name": "Virology"}, "field": {"id": "https://openalex.org/fields/24", "display_name": "Immunology and Microbiology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.10440000146627426, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.05649999901652336, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.8123180866241455}, {"id": "https://openalex.org/keywords/enumeration", "display_name": "Enumeration", "score": 0.726954460144043}, {"id": "https://openalex.org/keywords/population", "display_name": "Population", "score": 0.6281314492225647}, {"id": "https://openalex.org/keywords/cd8", "display_name": "CD8", "score": 0.6120585799217224}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.5368168354034424}, {"id": "https://openalex.org/keywords/lymphocyte-subsets", "display_name": "Lymphocyte subsets", "score": 0.5360840559005737}, {"id": "https://openalex.org/keywords/lymphocyte", "display_name": "Lymphocyte", "score": 0.514318585395813}, {"id": "https://openalex.org/keywords/immunology", "display_name": "Immunology", "score": 0.492367148399353}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.36404597759246826}, {"id": "https://openalex.org/keywords/mathematics", "display_name": "Mathematics", "score": 0.17011919617652893}, {"id": "https://openalex.org/keywords/immune-system", "display_name": "Immune system", "score": 0.15472465753555298}, {"id": "https://openalex.org/keywords/combinatorics", "display_name": "Combinatorics", "score": 0.05597361922264099}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.8123180866241455}, {"id": "https://openalex.org/C156340839", "wikidata": "https://www.wikidata.org/wiki/Q2704791", "display_name": "Enumeration", "level": 2, "score": 0.726954460144043}, {"id": "https://openalex.org/C2908647359", "wikidata": "https://www.wikidata.org/wiki/Q2625603", "display_name": "Population", "level": 2, "score": 0.6281314492225647}, {"id": "https://openalex.org/C167672396", "wikidata": "https://www.wikidata.org/wiki/Q417800", "display_name": "CD8", "level": 3, "score": 0.6120585799217224}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.5368168354034424}, {"id": "https://openalex.org/C3020391436", "wikidata": "https://www.wikidata.org/wiki/Q715347", "display_name": "Lymphocyte subsets", "level": 4, "score": 0.5360840559005737}, {"id": "https://openalex.org/C2777761686", "wikidata": "https://www.wikidata.org/wiki/Q715347", "display_name": "Lymphocyte", "level": 2, "score": 0.514318585395813}, {"id": "https://openalex.org/C203014093", "wikidata": "https://www.wikidata.org/wiki/Q101929", "display_name": "Immunology", "level": 1, "score": 0.492367148399353}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.36404597759246826}, {"id": "https://openalex.org/C33923547", "wikidata": "https://www.wikidata.org/wiki/Q395", "display_name": "Mathematics", "level": 0, "score": 0.17011919617652893}, {"id": "https://openalex.org/C8891405", "wikidata": "https://www.wikidata.org/wiki/Q1059", "display_name": "Immune system", "level": 2, "score": 0.15472465753555298}, {"id": "https://openalex.org/C114614502", "wikidata": "https://www.wikidata.org/wiki/Q76592", "display_name": "Combinatorics", "level": 1, "score": 0.05597361922264099}, {"id": "https://openalex.org/C99454951", "wikidata": "https://www.wikidata.org/wiki/Q932068", "display_name": "Environmental health", "level": 1, "score": 0.0}], "mesh": [{"descriptor_ui": "D000293", "descriptor_name": "Adolescent", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000293", "descriptor_name": "Adolescent", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000293", "descriptor_name": "Adolescent", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000367", "descriptor_name": "Age Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000367", "descriptor_name": "Age Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000367", "descriptor_name": "Age Factors", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007194", "descriptor_name": "India", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007194", "descriptor_name": "India", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007194", "descriptor_name": "India", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008875", "descriptor_name": "Middle Aged", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012727", "descriptor_name": "Sex Characteristics", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012727", "descriptor_name": "Sex Characteristics", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012727", "descriptor_name": "Sex Characteristics", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016130", "descriptor_name": "Immunophenotyping", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016131", "descriptor_name": "Lymphocyte Subsets", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D016131", "descriptor_name": "Lymphocyte Subsets", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D016131", "descriptor_name": "Lymphocyte Subsets", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D055815", "descriptor_name": "Young Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D055815", "descriptor_name": "Young Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D055815", "descriptor_name": "Young Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 4, "locations": [{"id": "doi:10.4103/0019-5359.42725", "is_oa": false, "landing_page_url": "https://doi.org/10.4103/0019-5359.42725", "pdf_url": null, "source": {"id": "https://openalex.org/S122944797", "display_name": "Indian Journal of Medical Sciences", "issn_l": "0019-5359", "issn": ["0019-5359", "1998-3654"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320448", "host_organization_name": "Medknow", "host_organization_lineage": ["https://openalex.org/P4310320448", "https://openalex.org/P4310318547"], "host_organization_lineage_names": ["Medknow", "Wolters Kluwer"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Indian Journal of Medical Sciences", "raw_type": "journal-article"}, {"id": "pmid:19008613", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/19008613", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Indian journal of medical sciences", "raw_type": null}, {"id": "pmh:oai:utoronto.scholaris.ca:1807/55166", "is_oa": true, "landing_page_url": "http://hdl.handle.net/1807/55166", "pdf_url": "https://utoronto.scholaris.ca/bitstreams/02e9e483-558a-43a8-9222-eb3c4fffafa4/download", "source": {"id": "https://openalex.org/S7407055458", "display_name": "TSpace", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": null, "raw_type": "Article"}, {"id": "pmh:cria:bioline:ms:ms08071", "is_oa": false, "landing_page_url": "http://www.bioline.org.br/abstract?id=ms08071", "pdf_url": null, "source": {"id": "https://openalex.org/S4306402188", "display_name": "Bioline International (Bioline International)", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": "Indian Journal of Medical Sciences (ISSN: 0019-5359) Vol 62 Num 10", "raw_type": "AA"}], "best_oa_location": {"id": "pmh:oai:utoronto.scholaris.ca:1807/55166", "is_oa": true, "landing_page_url": "http://hdl.handle.net/1807/55166", "pdf_url": "https://utoronto.scholaris.ca/bitstreams/02e9e483-558a-43a8-9222-eb3c4fffafa4/download", "source": {"id": "https://openalex.org/S7407055458", "display_name": "TSpace", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": null, "host_organization_name": null, "host_organization_lineage": [], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "submittedVersion", "is_accepted": false, "is_published": false, "raw_source_name": null, "raw_type": "Article"}, "sustainable_development_goals": [{"display_name": "Good health and well-being", "id": "https://metadata.un.org/sdg/3", "score": 0.5600000023841858}], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W1978753784.pdf"}, "referenced_works_count": 22, "referenced_works": ["https://openalex.org/W19515326", "https://openalex.org/W88094121", "https://openalex.org/W1965450725", "https://openalex.org/W1975797028", "https://openalex.org/W1989819664", "https://openalex.org/W1991829757", "https://openalex.org/W2003414972", "https://openalex.org/W2023700885", "https://openalex.org/W2033340742", "https://openalex.org/W2036608631", "https://openalex.org/W2038243010", "https://openalex.org/W2061296252", "https://openalex.org/W2104120663", "https://openalex.org/W2116625966", "https://openalex.org/W2118800567", "https://openalex.org/W2119197472", "https://openalex.org/W2120384265", "https://openalex.org/W2149560102", "https://openalex.org/W2167599756", "https://openalex.org/W2328979108", "https://openalex.org/W2412480297", "https://openalex.org/W2526743575"], "related_works": ["https://openalex.org/W2009659738", "https://openalex.org/W2368095207", "https://openalex.org/W2421838963", "https://openalex.org/W2362263334", "https://openalex.org/W2361651490", "https://openalex.org/W2391831627", "https://openalex.org/W2367922297", "https://openalex.org/W2071537108", "https://openalex.org/W2992488049", "https://openalex.org/W1987827138"], "abstract_inverted_index": {"BACKGROUND:": [0], "The": [1, 58, 159, 196, 219], "enumeration": [2], "of": [3, 8, 40, 45, 200, 207], "absolute": [4, 41, 86, 118, 131, 145, 220], "CD4": [5, 28, 132, 223], "counts": [6, 120, 133, 147, 224], "is": [7], "primary": [9], "importance,": [10], "since": [11], "therapeutic": [12], "protocols": [13], "for": [14, 26, 60, 109, 163, 169, 173, 185], "HIV1": [15], "patients": [16], "are": [17, 134, 148, 203, 229, 239], "based": [18], "on": [19], "these.": [20], "AIMS:": [21], "To": [22], "establish": [23], "reference": [24, 183], "ranges": [25, 184], "the": [27, 33, 66, 73, 85, 92, 164, 190, 208, 216, 226, 242, 247], "and": [29, 43, 72, 103, 127, 141, 155, 172, 212, 222, 225], "CD8": [30, 146], "T-lymphocytes": [31], "in": [32, 50, 231, 234], "Indian": [34, 187], "population.": [35, 218], "SETTINGS": [36], "AND": [37, 56], "DESIGN:": [38], "Enumeration": [39], "numbers": [42], "percentages": [44], "lymphocyte": [46, 87, 197], "subsets": [47, 198], "was": [48, 89, 167], "performed": [49], "252": [51], "healthy": [52], "adult": [53], "Indians.": [54], "METHODS": [55], "MATERIALS:": [57], "assays": [59], "SPT": [61], "were": [62, 107, 115], "carried": [63], "out": [64], "using": [65, 91, 189], "Beckman": [67], "EPICS": [68], "XL-MCL": [69], "flow": [70], "cytometer": [71], "cytostat": [74], "tetraCHROME": [75], "reagent": [76], "containing": [77], "CD45/CD8/CD4/CD3": [78], "monoclonal": [79], "antibodies.": [80], "For": [81], "comparison": [82], "with": [83], "DPT": [84, 243], "count": [88], "obtained": [90, 240], "Coulter": [93], "STK-S": [94], "fully": [95, 191], "automated": [96, 192], "hematology": [97], "analyzer.": [98], "STATISTICAL": [99], "ANALYSIS:": [100], "Regression": [101], "analysis": [102], "Students": [104], "t": [105], "test": [106], "used": [108], "data": [110], "analysis.": [111], "RESULTS:": [112], "Median": [113], "values": [114, 199, 238], "as": [116, 244], "follows;": [117], "CD3": [119, 221], "1446": [121], "cells/mm3": [122, 125, 129, 136, 139, 143, 150, 153, 157], "(total),": [123, 137, 151], "1361": [124], "(males)": [126, 140, 154], "1511": [128], "(females);": [130, 144], "771": [135], "705": [138], "839": [142], "555": [149], "552": [152], "561": [156], "(females).": [158], "median": [160], "CD4/CD8": [161], "ratio": [162, 228], "total": [165], "samples": [166], "1.34,": [168], "males": [170], "1.22": [171], "females": [174, 232], "1.49.": [175], "CONCLUSIONS:": [176], "In": [177], "this": [178], "study": [179], "we": [180], "have": [181], "established": [182], "normal": [186], "adults": [188], "Single": [193], "Platform": [194], "Technology.": [195], "our": [201], "population": [202, 209], "closer": [204], "to": [205, 246], "those": [206], "from": [210], "Botswana": [211], "China": [213], "rather": [214], "than": [215, 233], "Western": [217], "CD4:CD8": [227], "higher": [230, 237], "males.": [235], "Consistently": [236], "by": [241], "compared": [245], "SPT.": [248]}, "counts_by_year": [{"year": 2023, "cited_by_count": 2}, {"year": 2022, "cited_by_count": 3}, {"year": 2021, "cited_by_count": 4}, {"year": 2020, "cited_by_count": 5}, {"year": 2019, "cited_by_count": 2}, {"year": 2018, "cited_by_count": 2}, {"year": 2017, "cited_by_count": 1}, {"year": 2016, "cited_by_count": 2}, {"year": 2015, "cited_by_count": 4}, {"year": 2014, "cited_by_count": 5}, {"year": 2013, "cited_by_count": 1}, {"year": 2012, "cited_by_count": 6}], "updated_date": "2026-04-29T09:16:38.111599", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W1972370332", "doi": "https://doi.org/10.5858/arpa.2012-0377-oa", "title": "Biological Variations of Hematologic Parameters Determined by UniCel DxH 800 Hematology Analyzer", "display_name": "Biological Variations of Hematologic Parameters Determined by UniCel DxH 800 Hematology Analyzer", "relevance_score": 43.589542, "publication_year": 2013, "publication_date": "2013-07-30", "ids": {"openalex": "https://openalex.org/W1972370332", "doi": "https://doi.org/10.5858/arpa.2012-0377-oa", "mag": "1972370332", "pmid": "https://pubmed.ncbi.nlm.nih.gov/23899069"}, "language": "en", "primary_location": {"id": "doi:10.5858/arpa.2012-0377-oa", "is_oa": true, "landing_page_url": "https://doi.org/10.5858/arpa.2012-0377-oa", "pdf_url": "https://meridian.allenpress.com/aplm/article-pdf/137/8/1106/1611473/arpa_2012-0377-oa.pdf", "source": {"id": "https://openalex.org/S139062638", "display_name": "Archives of Pathology & Laboratory Medicine", "issn_l": "0003-9985", "issn": ["0003-9985", "1543-2165"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320259", "host_organization_name": "American Medical Association", "host_organization_lineage": ["https://openalex.org/P4310320259"], "host_organization_lineage_names": ["American Medical Association"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of Pathology and Laboratory Medicine", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": true, "oa_status": "bronze", "oa_url": "https://meridian.allenpress.com/aplm/article-pdf/137/8/1106/1611473/arpa_2012-0377-oa.pdf", "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5003327907", "display_name": "Pianhong Zhang", "orcid": null}, "institutions": [{"id": "https://openalex.org/I115592961", "display_name": "Jiangsu University", "ror": "https://ror.org/03jc41j30", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I115592961"]}, {"id": "https://openalex.org/I4210144213", "display_name": "Xylem (United States)", "ror": "https://ror.org/04j6nkt56", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210144213"]}, {"id": "https://openalex.org/I4210158318", "display_name": "Second Affiliated Hospital of Zhejiang University", "ror": "https://ror.org/059cjpv64", "country_code": "CN", "type": "healthcare", "lineage": ["https://openalex.org/I4210158318"]}], "countries": ["CN", "US"], "is_corresponding": true, "raw_author_name": "Pianhong Zhang", "raw_affiliation_strings": ["From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210158318"]}, {"raw_affiliation_string": "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210144213"]}, {"raw_affiliation_string": "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "institution_ids": ["https://openalex.org/I115592961"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5004061338", "display_name": "Huqiang Tang", "orcid": "https://orcid.org/0000-0002-6654-687X"}, "institutions": [{"id": "https://openalex.org/I115592961", "display_name": "Jiangsu University", "ror": "https://ror.org/03jc41j30", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I115592961"]}, {"id": "https://openalex.org/I4210144213", "display_name": "Xylem (United States)", "ror": "https://ror.org/04j6nkt56", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210144213"]}, {"id": "https://openalex.org/I4210158318", "display_name": "Second Affiliated Hospital of Zhejiang University", "ror": "https://ror.org/059cjpv64", "country_code": "CN", "type": "healthcare", "lineage": ["https://openalex.org/I4210158318"]}], "countries": ["CN", "US"], "is_corresponding": false, "raw_author_name": "Huqiang Tang", "raw_affiliation_strings": ["From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210158318"]}, {"raw_affiliation_string": "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "institution_ids": ["https://openalex.org/I115592961"]}, {"raw_affiliation_string": "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210144213"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5011152446", "display_name": "Keqing Chen", "orcid": null}, "institutions": [{"id": "https://openalex.org/I115592961", "display_name": "Jiangsu University", "ror": "https://ror.org/03jc41j30", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I115592961"]}, {"id": "https://openalex.org/I4210144213", "display_name": "Xylem (United States)", "ror": "https://ror.org/04j6nkt56", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210144213"]}, {"id": "https://openalex.org/I4210158318", "display_name": "Second Affiliated Hospital of Zhejiang University", "ror": "https://ror.org/059cjpv64", "country_code": "CN", "type": "healthcare", "lineage": ["https://openalex.org/I4210158318"]}], "countries": ["CN", "US"], "is_corresponding": false, "raw_author_name": "Keqing Chen", "raw_affiliation_strings": ["From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210158318"]}, {"raw_affiliation_string": "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "institution_ids": ["https://openalex.org/I115592961"]}, {"raw_affiliation_string": "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210144213"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5100394750", "display_name": "Yingying Chen", "orcid": "https://orcid.org/0000-0002-3994-766X"}, "institutions": [{"id": "https://openalex.org/I115592961", "display_name": "Jiangsu University", "ror": "https://ror.org/03jc41j30", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I115592961"]}, {"id": "https://openalex.org/I4210144213", "display_name": "Xylem (United States)", "ror": "https://ror.org/04j6nkt56", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210144213"]}, {"id": "https://openalex.org/I4210158318", "display_name": "Second Affiliated Hospital of Zhejiang University", "ror": "https://ror.org/059cjpv64", "country_code": "CN", "type": "healthcare", "lineage": ["https://openalex.org/I4210158318"]}], "countries": ["CN", "US"], "is_corresponding": false, "raw_author_name": "Yingying Chen", "raw_affiliation_strings": ["From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210158318"]}, {"raw_affiliation_string": "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "institution_ids": ["https://openalex.org/I115592961"]}, {"raw_affiliation_string": "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210144213"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5055908165", "display_name": "Dongsheng Xu", "orcid": "https://orcid.org/0000-0002-8477-5377"}, "institutions": [{"id": "https://openalex.org/I115592961", "display_name": "Jiangsu University", "ror": "https://ror.org/03jc41j30", "country_code": "CN", "type": "education", "lineage": ["https://openalex.org/I115592961"]}, {"id": "https://openalex.org/I4210144213", "display_name": "Xylem (United States)", "ror": "https://ror.org/04j6nkt56", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210144213"]}, {"id": "https://openalex.org/I4210158318", "display_name": "Second Affiliated Hospital of Zhejiang University", "ror": "https://ror.org/059cjpv64", "country_code": "CN", "type": "healthcare", "lineage": ["https://openalex.org/I4210158318"]}], "countries": ["CN", "US"], "is_corresponding": false, "raw_author_name": "Dongsheng Xu", "raw_affiliation_strings": ["From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)"], "raw_orcid": null, "affiliations": [{"raw_affiliation_string": "From the Clinical Laboratory Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China (Dr Zhang and Messrs Tang and K. Chen); the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen); and the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210158318"]}, {"raw_affiliation_string": "the School of Medical Sciences and Laboratory, Jiangsu University, Jiangsu, China (Ms. Y. Chen)", "institution_ids": ["https://openalex.org/I115592961"]}, {"raw_affiliation_string": "the Department of Hematopathology, CBLPath, Inc, Rye Brook, New York (Dr Xu)", "institution_ids": ["https://openalex.org/I4210144213"]}]}], "institutions": [], "countries_distinct_count": 2, "institutions_distinct_count": 5, "corresponding_author_ids": ["https://openalex.org/A5003327907"], "corresponding_institution_ids": ["https://openalex.org/I115592961", "https://openalex.org/I4210144213", "https://openalex.org/I4210158318"], "apc_list": null, "apc_paid": null, "fwci": 1.9374, "has_fulltext": true, "cited_by_count": 31, "citation_normalized_percentile": {"value": 0.85217908, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 99}, "biblio": {"volume": "137", "issue": "8", "first_page": "1106", "last_page": "1110"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9491999745368958, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, "topics": [{"id": "https://openalex.org/T11314", "display_name": "Clinical Laboratory Practices and Quality Control", "score": 0.9491999745368958, "subfield": {"id": "https://openalex.org/subfields/2737", "display_name": "Physiology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T13374", "display_name": "Hematological disorders and diagnostics", "score": 0.006099999882280827, "subfield": {"id": "https://openalex.org/subfields/2711", "display_name": "Emergency Medicine"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}, {"id": "https://openalex.org/T10345", "display_name": "Hematopoietic Stem Cell Transplantation", "score": 0.00559999980032444, "subfield": {"id": "https://openalex.org/subfields/2720", "display_name": "Hematology"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/hematology-analyzer", "display_name": "Hematology analyzer", "score": 0.7543306350708008}, {"id": "https://openalex.org/keywords/population", "display_name": "Population", "score": 0.5212807655334473}, {"id": "https://openalex.org/keywords/hematology", "display_name": "Hematology", "score": 0.511188805103302}, {"id": "https://openalex.org/keywords/context", "display_name": "Context (archaeology)", "score": 0.4792882800102234}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.46466171741485596}, {"id": "https://openalex.org/keywords/spectrum-analyzer", "display_name": "Spectrum analyzer", "score": 0.4309297204017639}, {"id": "https://openalex.org/keywords/statistics", "display_name": "Statistics", "score": 0.41134870052337646}, {"id": "https://openalex.org/keywords/internal-medicine", "display_name": "Internal medicine", "score": 0.33222049474716187}, {"id": "https://openalex.org/keywords/mathematics", "display_name": "Mathematics", "score": 0.3116895258426666}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.2531321048736572}, {"id": "https://openalex.org/keywords/biology", "display_name": "Biology", "score": 0.20072993636131287}], "concepts": [{"id": "https://openalex.org/C2993758460", "wikidata": "https://www.wikidata.org/wiki/Q65067531", "display_name": "Hematology analyzer", "level": 2, "score": 0.7543306350708008}, {"id": "https://openalex.org/C2908647359", "wikidata": "https://www.wikidata.org/wiki/Q2625603", "display_name": "Population", "level": 2, "score": 0.5212807655334473}, {"id": "https://openalex.org/C194409129", "wikidata": "https://www.wikidata.org/wiki/Q103824", "display_name": "Hematology", "level": 2, "score": 0.511188805103302}, {"id": "https://openalex.org/C2779343474", "wikidata": "https://www.wikidata.org/wiki/Q3109175", "display_name": "Context (archaeology)", "level": 2, "score": 0.4792882800102234}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.46466171741485596}, {"id": "https://openalex.org/C158007255", "wikidata": "https://www.wikidata.org/wiki/Q1055222", "display_name": "Spectrum analyzer", "level": 2, "score": 0.4309297204017639}, {"id": "https://openalex.org/C105795698", "wikidata": "https://www.wikidata.org/wiki/Q12483", "display_name": "Statistics", "level": 1, "score": 0.41134870052337646}, {"id": "https://openalex.org/C126322002", "wikidata": "https://www.wikidata.org/wiki/Q11180", "display_name": "Internal medicine", "level": 1, "score": 0.33222049474716187}, {"id": "https://openalex.org/C33923547", "wikidata": "https://www.wikidata.org/wiki/Q395", "display_name": "Mathematics", "level": 0, "score": 0.3116895258426666}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.2531321048736572}, {"id": "https://openalex.org/C86803240", "wikidata": "https://www.wikidata.org/wiki/Q420", "display_name": "Biology", "level": 0, "score": 0.20072993636131287}, {"id": "https://openalex.org/C76155785", "wikidata": "https://www.wikidata.org/wiki/Q418", "display_name": "Telecommunications", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C99454951", "wikidata": "https://www.wikidata.org/wiki/Q932068", "display_name": "Environmental health", "level": 1, "score": 0.0}, {"id": "https://openalex.org/C151730666", "wikidata": "https://www.wikidata.org/wiki/Q7205", "display_name": "Paleontology", "level": 1, "score": 0.0}], "mesh": [{"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000328", "descriptor_name": "Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000704", "descriptor_name": "Analysis of Variance", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000704", "descriptor_name": "Analysis of Variance", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D000704", "descriptor_name": "Analysis of Variance", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005260", "descriptor_name": "Female", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000592", "qualifier_name": "standards", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D006403", "descriptor_name": "Hematologic Tests", "qualifier_ui": "Q000706", "qualifier_name": "statistics & numerical data", "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008297", "descriptor_name": "Male", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012016", "descriptor_name": "Reference Values", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D055815", "descriptor_name": "Young Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D055815", "descriptor_name": "Young Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D055815", "descriptor_name": "Young Adult", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "doi:10.5858/arpa.2012-0377-oa", "is_oa": true, "landing_page_url": "https://doi.org/10.5858/arpa.2012-0377-oa", "pdf_url": "https://meridian.allenpress.com/aplm/article-pdf/137/8/1106/1611473/arpa_2012-0377-oa.pdf", "source": {"id": "https://openalex.org/S139062638", "display_name": "Archives of Pathology & Laboratory Medicine", "issn_l": "0003-9985", "issn": ["0003-9985", "1543-2165"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320259", "host_organization_name": "American Medical Association", "host_organization_lineage": ["https://openalex.org/P4310320259"], "host_organization_lineage_names": ["American Medical Association"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of Pathology and Laboratory Medicine", "raw_type": "journal-article"}, {"id": "pmid:23899069", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/23899069", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of pathology & laboratory medicine", "raw_type": null}], "best_oa_location": {"id": "doi:10.5858/arpa.2012-0377-oa", "is_oa": true, "landing_page_url": "https://doi.org/10.5858/arpa.2012-0377-oa", "pdf_url": "https://meridian.allenpress.com/aplm/article-pdf/137/8/1106/1611473/arpa_2012-0377-oa.pdf", "source": {"id": "https://openalex.org/S139062638", "display_name": "Archives of Pathology & Laboratory Medicine", "issn_l": "0003-9985", "issn": ["0003-9985", "1543-2165"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320259", "host_organization_name": "American Medical Association", "host_organization_lineage": ["https://openalex.org/P4310320259"], "host_organization_lineage_names": ["American Medical Association"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Archives of Pathology and Laboratory Medicine", "raw_type": "journal-article"}, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": true, "pdf": true}, "content_urls": {"pdf": "https://content.openalex.org/works/W1972370332.pdf", "grobid_xml": "https://content.openalex.org/works/W1972370332.grobid-xml"}, "referenced_works_count": 17, "referenced_works": ["https://openalex.org/W3142897", "https://openalex.org/W62693281", "https://openalex.org/W194217467", "https://openalex.org/W1565959468", "https://openalex.org/W1656894086", "https://openalex.org/W1863804520", "https://openalex.org/W1978730145", "https://openalex.org/W1994774009", "https://openalex.org/W2036552939", "https://openalex.org/W2070375393", "https://openalex.org/W2078878423", "https://openalex.org/W2119950421", "https://openalex.org/W2151259375", "https://openalex.org/W2156475148", "https://openalex.org/W2332288167", "https://openalex.org/W2417854739", "https://openalex.org/W2955211058"], "related_works": ["https://openalex.org/W2394278344", "https://openalex.org/W2367382573", "https://openalex.org/W3114788508", "https://openalex.org/W2364386882", "https://openalex.org/W2352314160", "https://openalex.org/W2371899913", "https://openalex.org/W2383340743", "https://openalex.org/W2391004426", "https://openalex.org/W2355540433", "https://openalex.org/W1601719760"], "abstract_inverted_index": {"CONTEXT:": [0], "The": [1, 124], "Coulter": [2, 52], "DxH": [3, 129], "800": [4, 130], "hematology": [5, 53], "analyzer": [6], "can": [7], "determine": [8], "conventional": [9, 46, 116], "hematologic": [10, 17, 38, 47, 117], "parameters.": [11], "It": [12], "also": [13], "provides": [14], "many": [15], "new": [16, 37, 203, 223], "parameters,": [18], "some": [19], "of": [20, 36, 45, 106, 127, 137, 140, 158, 212, 219, 222, 232], "which": [21], "show": [22], "potential": [23], "clinical": [24, 234], "utility.": [25], "OBJECTIVES:": [26], "To": [27], "study,": [28], "for": [29, 114, 131, 146, 191], "the": [30, 33, 42, 50, 96, 103, 115, 128, 166, 210, 230, 237], "first": [31], "time,": [32], "biological": [34, 43, 112, 144, 156, 178, 200, 220], "variations": [35, 44, 113, 157, 221], "parameters": [39, 48, 118, 133, 148, 160, 204, 224], "and": [40, 61, 83, 110, 154, 180, 198], "reinvestigate": [41], "using": [49, 88, 102], "newest": [51], "analyzer.": [54, 91], "DESIGN:": [55], "Forty": [56], "adult": [57], "volunteers": [58], "(21": [59], "women": [60], "19": [62], "men)": [63], "were": [64, 74, 100, 119], "included.": [65], "All": [66], "participants": [67], "maintained": [68], "their": [69], "normal": [70], "lifestyles.": [71], "Blood": [72], "samples": [73], "drawn": [75], "in": [76, 193, 229, 236], "duplicate": [77], "by": [78], "a": [79, 89], "single": [80, 90], "experienced": [81], "phlebotomist": [82], "analyzed": [84], "within": [85], "2": [86], "hours": [87], "Before": [92], "each": [93], "batch": [94], "analysis,": [95], "instrument": [97], "quality": [98, 194], "controls": [99], "performed": [101], "same": [104], "lots": [105], "reagents.": [107], "RESULTS:": [108], "Within-subject": [109], "between-subject": [111, 143, 199], "compatible": [120], "with": [121], "published": [122], "data.": [123], "analytic": [125, 181], "variation": [126, 179, 201], "these": [132], "appeared": [134], "smaller.": [135], "Index": [136], "individuality": [138], "(ratio": [139], "within-subject": [141, 177, 197], "to": [142, 186, 208], "variation)": [145], "all": [147], "was": [149], "low.": [150], "In": [151], "addition,": [152], "intraday": [153], "interday": [155], "most": [159], "studied": [161], "are": [162, 172], "fairly": [163], "constant": [164], "among": [165], "population": [167], "examined.": [168], "CONCLUSIONS:": [169], "These": [170], "observations": [171], "clinically": [173], "valuable.": [174], "Data": [175], "on": [176, 202], "precision": [182], "may": [183, 205], "be": [184], "used": [185], "generate": [187], "objective": [188], "delta-check": [189], "values": [190], "use": [192], "management.": [195], "Comparing": [196], "allow": [206], "us": [207], "decide": [209], "utility": [211], "traditional": [213], "population-based": [214], "reference": [215], "ranges.": [216], "Furthermore,": [217], "documentation": [218], "is": [225], "an": [226], "essential": [227], "prerequisite": [228], "development": [231], "any": [233], "application": [235], "future.": [238]}, "counts_by_year": [{"year": 2026, "cited_by_count": 1}, {"year": 2025, "cited_by_count": 1}, {"year": 2024, "cited_by_count": 1}, {"year": 2023, "cited_by_count": 1}, {"year": 2021, "cited_by_count": 5}, {"year": 2020, "cited_by_count": 1}, {"year": 2019, "cited_by_count": 6}, {"year": 2018, "cited_by_count": 2}, {"year": 2017, "cited_by_count": 2}, {"year": 2016, "cited_by_count": 5}, {"year": 2015, "cited_by_count": 2}, {"year": 2014, "cited_by_count": 4}], "updated_date": "2026-05-10T08:33:47.465468", "created_date": "2025-10-10T00:00:00"}, {"id": "https://openalex.org/W2045267057", "doi": "https://doi.org/10.1111/j.1749-6632.1986.tb42032.x", "title": "Controls for Flow Cytometers in Hematology and Cellular Immunology", "display_name": "Controls for Flow Cytometers in Hematology and Cellular Immunology", "relevance_score": 41.276947, "publication_year": 1986, "publication_date": "1986-06-01", "ids": {"openalex": "https://openalex.org/W2045267057", "doi": "https://doi.org/10.1111/j.1749-6632.1986.tb42032.x", "mag": "2045267057", "pmid": "https://pubmed.ncbi.nlm.nih.gov/3089119"}, "language": "en", "primary_location": {"id": "doi:10.1111/j.1749-6632.1986.tb42032.x", "is_oa": false, "landing_page_url": "https://doi.org/10.1111/j.1749-6632.1986.tb42032.x", "pdf_url": null, "source": {"id": "https://openalex.org/S8802318", "display_name": "Annals of the New York Academy of Sciences", "issn_l": "0077-8923", "issn": ["0077-8923", "1749-6632"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Annals of the New York Academy of Sciences", "raw_type": "journal-article"}, "type": "article", "indexed_in": ["crossref", "pubmed"], "open_access": {"is_oa": false, "oa_status": "closed", "oa_url": null, "any_repository_has_fulltext": false}, "authorships": [{"author_position": "first", "author": {"id": "https://openalex.org/A5022094836", "display_name": "Michael C. Brown", "orcid": "https://orcid.org/0000-0002-3957-1164"}, "institutions": [{"id": "https://openalex.org/I4210157095", "display_name": "Ortho Clinical Diagnostics (United States)", "ror": "https://ror.org/04npmfz39", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210157095"]}], "countries": ["US"], "is_corresponding": true, "raw_author_name": "MICHAEL C. BROWN", "raw_affiliation_strings": ["Ortho Diagnostic Systems Inc. 410 University Avenue Westwood, Massachusetts 02090"], "affiliations": [{"raw_affiliation_string": "Ortho Diagnostic Systems Inc. 410 University Avenue Westwood, Massachusetts 02090", "institution_ids": ["https://openalex.org/I4210157095"]}]}, {"author_position": "middle", "author": {"id": "https://openalex.org/A5112367680", "display_name": "Robert A. Hoffman", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210157095", "display_name": "Ortho Clinical Diagnostics (United States)", "ror": "https://ror.org/04npmfz39", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210157095"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "ROBERT A. HOFFMAN", "raw_affiliation_strings": ["Ortho Diagnostic Systems Inc. 410 University Avenue Westwood, Massachusetts 02090"], "affiliations": [{"raw_affiliation_string": "Ortho Diagnostic Systems Inc. 410 University Avenue Westwood, Massachusetts 02090", "institution_ids": ["https://openalex.org/I4210157095"]}]}, {"author_position": "last", "author": {"id": "https://openalex.org/A5010423124", "display_name": "Stefan J. Kirchanski", "orcid": null}, "institutions": [{"id": "https://openalex.org/I4210157095", "display_name": "Ortho Clinical Diagnostics (United States)", "ror": "https://ror.org/04npmfz39", "country_code": "US", "type": "company", "lineage": ["https://openalex.org/I4210157095"]}], "countries": ["US"], "is_corresponding": false, "raw_author_name": "STEFAN J. KIRCHANSKI", "raw_affiliation_strings": ["Ortho Diagnostic Systems Inc. 410 University Avenue Westwood, Massachusetts 02090"], "affiliations": [{"raw_affiliation_string": "Ortho Diagnostic Systems Inc. 410 University Avenue Westwood, Massachusetts 02090", "institution_ids": ["https://openalex.org/I4210157095"]}]}], "institutions": [], "countries_distinct_count": 1, "institutions_distinct_count": 3, "corresponding_author_ids": ["https://openalex.org/A5022094836"], "corresponding_institution_ids": ["https://openalex.org/I4210157095"], "apc_list": {"value": 4840, "currency": "USD", "value_usd": 4840}, "apc_paid": null, "fwci": 0.7814, "has_fulltext": false, "cited_by_count": 27, "citation_normalized_percentile": {"value": 0.70545455, "is_in_top_1_percent": false, "is_in_top_10_percent": false}, "cited_by_percentile_year": {"min": 89, "max": 96}, "biblio": {"volume": "468", "issue": "1", "first_page": "93", "last_page": "103"}, "is_retracted": false, "is_paratext": false, "is_xpac": false, "primary_topic": {"id": "https://openalex.org/T11289", "display_name": "Single-cell and spatial transcriptomics", "score": 0.9815999865531921, "subfield": {"id": "https://openalex.org/subfields/1312", "display_name": "Molecular Biology"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, "topics": [{"id": "https://openalex.org/T11289", "display_name": "Single-cell and spatial transcriptomics", "score": 0.9815999865531921, "subfield": {"id": "https://openalex.org/subfields/1312", "display_name": "Molecular Biology"}, "field": {"id": "https://openalex.org/fields/13", "display_name": "Biochemistry, Genetics and Molecular Biology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T11020", "display_name": "Immune Cell Function and Interaction", "score": 0.9248999953269958, "subfield": {"id": "https://openalex.org/subfields/2403", "display_name": "Immunology"}, "field": {"id": "https://openalex.org/fields/24", "display_name": "Immunology and Microbiology"}, "domain": {"id": "https://openalex.org/domains/1", "display_name": "Life Sciences"}}, {"id": "https://openalex.org/T11157", "display_name": "Chronic Lymphocytic Leukemia Research", "score": 0.9175000190734863, "subfield": {"id": "https://openalex.org/subfields/2716", "display_name": "Genetics"}, "field": {"id": "https://openalex.org/fields/27", "display_name": "Medicine"}, "domain": {"id": "https://openalex.org/domains/4", "display_name": "Health Sciences"}}], "keywords": [{"id": "https://openalex.org/keywords/citation", "display_name": "Citation", "score": 0.617544412612915}, {"id": "https://openalex.org/keywords/library-science", "display_name": "Library science", "score": 0.5470009446144104}, {"id": "https://openalex.org/keywords/associate-editor", "display_name": "Associate editor", "score": 0.43632882833480835}, {"id": "https://openalex.org/keywords/medicine", "display_name": "Medicine", "score": 0.3814981281757355}, {"id": "https://openalex.org/keywords/classics", "display_name": "Classics", "score": 0.3278614282608032}, {"id": "https://openalex.org/keywords/computer-science", "display_name": "Computer science", "score": 0.26271939277648926}, {"id": "https://openalex.org/keywords/art", "display_name": "Art", "score": 0.21898630261421204}], "concepts": [{"id": "https://openalex.org/C2778805511", "wikidata": "https://www.wikidata.org/wiki/Q1713", "display_name": "Citation", "level": 2, "score": 0.617544412612915}, {"id": "https://openalex.org/C161191863", "wikidata": "https://www.wikidata.org/wiki/Q199655", "display_name": "Library science", "level": 1, "score": 0.5470009446144104}, {"id": "https://openalex.org/C2993853449", "wikidata": "https://www.wikidata.org/wiki/Q194105", "display_name": "Associate editor", "level": 2, "score": 0.43632882833480835}, {"id": "https://openalex.org/C71924100", "wikidata": "https://www.wikidata.org/wiki/Q11190", "display_name": "Medicine", "level": 0, "score": 0.3814981281757355}, {"id": "https://openalex.org/C74916050", "wikidata": "https://www.wikidata.org/wiki/Q841090", "display_name": "Classics", "level": 1, "score": 0.3278614282608032}, {"id": "https://openalex.org/C41008148", "wikidata": "https://www.wikidata.org/wiki/Q21198", "display_name": "Computer science", "level": 0, "score": 0.26271939277648926}, {"id": "https://openalex.org/C142362112", "wikidata": "https://www.wikidata.org/wiki/Q735", "display_name": "Art", "level": 0, "score": 0.21898630261421204}], "mesh": [{"descriptor_ui": "D000911", "descriptor_name": "Antibodies, Monoclonal", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D000911", "descriptor_name": "Antibodies, Monoclonal", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D000911", "descriptor_name": "Antibodies, Monoclonal", "qualifier_ui": "Q000032", "qualifier_name": "analysis", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D001772", "descriptor_name": "Blood Cell Count", "qualifier_ui": "Q000295", "qualifier_name": "instrumentation", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D005434", "descriptor_name": "Flow Cytometry", "qualifier_ui": "Q000379", "qualifier_name": "methods", "is_major_topic": false}, {"descriptor_ui": "D005452", "descriptor_name": "Fluoresceins", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005452", "descriptor_name": "Fluoresceins", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005452", "descriptor_name": "Fluoresceins", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005455", "descriptor_name": "Fluorescent Antibody Technique", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005455", "descriptor_name": "Fluorescent Antibody Technique", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D005455", "descriptor_name": "Fluorescent Antibody Technique", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D006801", "descriptor_name": "Humans", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D007111", "descriptor_name": "Immunity, Cellular", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007111", "descriptor_name": "Immunity, Cellular", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D007111", "descriptor_name": "Immunity, Cellular", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D008027", "descriptor_name": "Light", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008027", "descriptor_name": "Light", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D008027", "descriptor_name": "Light", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D011786", "descriptor_name": "Quality Control", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012015", "descriptor_name": "Reference Standards", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D012015", "descriptor_name": "Reference Standards", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D012015", "descriptor_name": "Reference Standards", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": true}, {"descriptor_ui": "D012542", "descriptor_name": "Scattering, Radiation", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012542", "descriptor_name": "Scattering, Radiation", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D012542", "descriptor_name": "Scattering, Radiation", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013861", "descriptor_name": "Thiocyanates", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013861", "descriptor_name": "Thiocyanates", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D013861", "descriptor_name": "Thiocyanates", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016650", "descriptor_name": "Fluorescein-5-isothiocyanate", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016650", "descriptor_name": "Fluorescein-5-isothiocyanate", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}, {"descriptor_ui": "D016650", "descriptor_name": "Fluorescein-5-isothiocyanate", "qualifier_ui": null, "qualifier_name": null, "is_major_topic": false}], "locations_count": 2, "locations": [{"id": "doi:10.1111/j.1749-6632.1986.tb42032.x", "is_oa": false, "landing_page_url": "https://doi.org/10.1111/j.1749-6632.1986.tb42032.x", "pdf_url": null, "source": {"id": "https://openalex.org/S8802318", "display_name": "Annals of the New York Academy of Sciences", "issn_l": "0077-8923", "issn": ["0077-8923", "1749-6632"], "is_oa": false, "is_in_doaj": false, "is_core": true, "host_organization": "https://openalex.org/P4310320595", "host_organization_name": "Wiley", "host_organization_lineage": ["https://openalex.org/P4310320595"], "host_organization_lineage_names": ["Wiley"], "type": "journal"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Annals of the New York Academy of Sciences", "raw_type": "journal-article"}, {"id": "pmid:3089119", "is_oa": false, "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/3089119", "pdf_url": null, "source": {"id": "https://openalex.org/S4306525036", "display_name": "PubMed", "issn_l": null, "issn": null, "is_oa": false, "is_in_doaj": false, "is_core": false, "host_organization": "https://openalex.org/I1299303238", "host_organization_name": "National Institutes of Health", "host_organization_lineage": ["https://openalex.org/I1299303238"], "host_organization_lineage_names": [], "type": "repository"}, "license": null, "license_id": null, "version": "publishedVersion", "is_accepted": true, "is_published": true, "raw_source_name": "Annals of the New York Academy of Sciences", "raw_type": null}], "best_oa_location": null, "sustainable_development_goals": [], "awards": [], "funders": [], "has_content": {"grobid_xml": false, "pdf": false}, "content_urls": null, "referenced_works_count": 5, "referenced_works": ["https://openalex.org/W84683391", "https://openalex.org/W192254448", "https://openalex.org/W1986295835", "https://openalex.org/W2324762769", "https://openalex.org/W2333251370"], "related_works": ["https://openalex.org/W2899084033", "https://openalex.org/W2748952813", "https://openalex.org/W3031052312", "https://openalex.org/W3032375762", "https://openalex.org/W1995515455", "https://openalex.org/W2080531066", "https://openalex.org/W3108674512", "https://openalex.org/W1506200166", "https://openalex.org/W2048182022", "https://openalex.org/W2604872355"], "abstract_inverted_index": {"The": [0, 104], "necessity": [1], "of": [2, 18, 41, 48, 67, 87, 94, 102, 107, 113, 129, 168, 191, 198, 201], "using": [3], "freshly": [4], "prepared": [5], "biological": [6], "samples": [7], "to": [8, 62, 160], "control": [9, 29, 43, 97, 169, 187, 202], "and": [10, 31, 34, 116, 131, 155, 188, 196, 211, 228], "calibrate": [11], "flow": [12, 19, 74], "cytometers": [13], "has": [14, 164], "impeded": [15], "the": [16, 22, 39, 64, 77], "utilization": [17], "cytometry": [20], "in": [21, 59, 91], "clinical": [23, 173], "laboratory": [24], "where": [25], "regulations": [26], "demand": [27], "careful": [28], "calibration": [30, 190], "yet": [32], "workload": [33], "technician": [35], "training": [36], "militate": [37], "against": [38], "preparation": [40, 98], "specialized": [42], "samples.": [44], "For": [45], "a": [46, 95, 111, 139], "number": [47], "years,": [49], "cell": [50, 70, 144, 157, 180], "preparations": [51, 79], "with": [52, 217, 225], "stabilized": [53, 78, 218], "properties": [54, 220], "have": [55, 176], "been": [56, 165, 177], "used": [57], "routinely": [58], "hematology": [60, 108, 133], "laboratories": [61], "evaluate": [63], "daily": [65], "performance": [66, 93, 154], "automated": [68, 143], "blood": [69], "counters": [71], "including": [72], "optical": [73], "cytometers.": [75], "Unfortunately,": [76], "do": [80], "not": [81], "necessarily": [82], "duplicate": [83], "many": [84], "important": [85], "aspects": [86, 128], "whole": [88], "blood,": [89], "resulting": [90], "variable": [92], "given": [96], "on": [99], "different": [100], "types": [101], "instrumentation.": [103], "new": [105, 114, 140], "generation": [106], "analyzers": [109], "measures": [110], "host": [112], "parameters": [115], "will": [117, 135, 203, 207], "require": [118], "more": [119], "sophisticated": [120], "controls": [121, 134, 150], "for": [122, 142, 152, 156, 172, 182, 189], "these": [123], "enhanced": [124], "parameters.": [125], "Some": [126], "practical": [127], "present": [130], "future": [132], "be": [136, 204, 223], "discussed.": [137], "Immunology,": [138], "area": [141], "analysis,": [145], "can": [146, 222, 229], "benefit": [147], "greatly": [148], "from": [149], "both": [151], "instrument": [153, 186], "staining.": [158], "Up": [159], "this": [161, 199], "time": [162], "there": [163], "little": [166], "availability": [167], "materials": [170], "suitable": [171], "immunology.": [174], "We": [175, 206], "evaluating": [178], "fluorochrome-stained": [179], "nuclei": [181], "use": [183, 197], "as": [184, 232], "an": [185], "immunofluorescence": [192], "analyses.": [193], "Our": [194], "development": [195], "type": [200], "described.": [205], "also": [208], "discuss": [209], "approaches": [210], "experiments": [212], "aimed": [213], "at": [214], "producing": [215], "cells": [216], "antigenic": [219], "which": [221], "stained": [224], "monoclonal": [226], "antibodies": [227], "thus": [230], "act": [231], "actual": [233], "reagent": [234], "controls.": [235]}, "counts_by_year": [{"year": 2023, "cited_by_count": 1}, {"year": 2020, "cited_by_count": 1}, {"year": 2017, "cited_by_count": 2}], "updated_date": "2025-11-06T03:46:38.306776", "created_date": "2025-10-10T00:00:00"}], "group_by": []}