{"id":"https://openalex.org/W4408216038","doi":"https://doi.org/10.56553/popets-2025-0072","title":"SecureED: Secure Multiparty Edit Distance for Genomic Sequences","display_name":"SecureED: Secure Multiparty Edit Distance for Genomic Sequences","publication_year":2025,"publication_date":"2025-03-07","ids":{"openalex":"https://openalex.org/W4408216038","doi":"https://doi.org/10.56553/popets-2025-0072"},"language":"en","primary_location":{"id":"doi:10.56553/popets-2025-0072","is_oa":true,"landing_page_url":"https://doi.org/10.56553/popets-2025-0072","pdf_url":"https://petsymposium.org/popets/2025/popets-2025-0072.pdf","source":{"id":"https://openalex.org/S4210183172","display_name":"Proceedings on Privacy Enhancing Technologies","issn_l":"2299-0984","issn":["2299-0984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings on Privacy Enhancing Technologies","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://petsymposium.org/popets/2025/popets-2025-0072.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091870127","display_name":"Jiahui Gao","orcid":"https://orcid.org/0000-0003-3821-2263"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jiahui Gao","raw_affiliation_strings":["Arizona State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arizona State University","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116549181","display_name":"Yagaagowtham Palanikumar","orcid":null},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yagaagowtham Palanikumar","raw_affiliation_strings":["Arizona State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arizona State University","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014585745","display_name":"Dimitris Mouris","orcid":"https://orcid.org/0000-0002-2601-203X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dimitris Mouris","raw_affiliation_strings":["Nillion"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nillion","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037078336","display_name":"Duong Tung Nguyen","orcid":"https://orcid.org/0000-0002-6072-0558"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Duong Nguyen","raw_affiliation_strings":["Arizona State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arizona State University","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028189452","display_name":"Ni Trieu","orcid":"https://orcid.org/0000-0001-6013-9512"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ni Trieu","raw_affiliation_strings":["Arizona State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arizona State University","institution_ids":["https://openalex.org/I55732556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5091870127"],"corresponding_institution_ids":["https://openalex.org/I55732556"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04319281,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2025","issue":"2","first_page":"479","last_page":"493"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.6122000217437744,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.6122000217437744,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/edit-distance","display_name":"Edit distance","score":0.6343672275543213},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5497697591781616},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.43923449516296387},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.36622798442840576},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.33515021204948425},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3314083516597748},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1858181655406952}],"concepts":[{"id":"https://openalex.org/C44359876","wikidata":"https://www.wikidata.org/wiki/Q5338467","display_name":"Edit distance","level":2,"score":0.6343672275543213},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5497697591781616},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43923449516296387},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.36622798442840576},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33515021204948425},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3314083516597748},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1858181655406952}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.56553/popets-2025-0072","is_oa":true,"landing_page_url":"https://doi.org/10.56553/popets-2025-0072","pdf_url":"https://petsymposium.org/popets/2025/popets-2025-0072.pdf","source":{"id":"https://openalex.org/S4210183172","display_name":"Proceedings on Privacy Enhancing Technologies","issn_l":"2299-0984","issn":["2299-0984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings on Privacy Enhancing Technologies","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.56553/popets-2025-0072","is_oa":true,"landing_page_url":"https://doi.org/10.56553/popets-2025-0072","pdf_url":"https://petsymposium.org/popets/2025/popets-2025-0072.pdf","source":{"id":"https://openalex.org/S4210183172","display_name":"Proceedings on Privacy Enhancing Technologies","issn_l":"2299-0984","issn":["2299-0984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings on Privacy Enhancing Technologies","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4408216038.pdf","grobid_xml":"https://content.openalex.org/works/W4408216038.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W2807937018"],"abstract_inverted_index":{"DNA":[0,19,56,152,174],"edit":[1,57],"distance":[2,58],"(ED)":[3],"measures":[4],"the":[5,53,76,134,140,147,179],"minimum":[6],"number":[7],"of":[8,96,125,178],"single":[9],"nucleotide":[10,181],"insertions,":[11],"substitutions,":[12],"or":[13,67],"deletions":[14],"required":[15],"to":[16,47,69,73,101,153],"convert":[17],"a":[18,84,92,107,119,129,168],"sequence":[20,31],"into":[21,143],"another.":[22],"ED":[23,109],"has":[24],"broad":[25],"applications":[26],"in":[27,44,91,117,150,165],"healthcare":[28],"such":[29,172],"as":[30,173],"alignment,":[32],"genome":[33],"assembly,":[34],"functional":[35],"annotation,":[36],"and":[37,71],"drug":[38],"discovery.":[39],"Privacy-preserving":[40],"computation":[41,164],"is":[42,128],"essential":[43],"this":[45,79],"context":[46],"protect":[48],"sensitive":[49],"genomic":[50],"data.":[51],"Nonetheless,":[52],"existing":[54,102],"secure":[55,108,163],"solutions":[59],"lack":[60],"efficiency":[61],"when":[62],"handling":[63],"large":[64],"data":[65],"sequences":[66,175],"resort":[68],"approximations":[70],"fail":[72],"accurately":[74],"compute":[75],"metric.":[77],"In":[78],"work,":[80],"we":[81,157],"introduce":[82,158],"ScureED,":[83],"protocol":[85,105,127],"that":[86,132],"tackles":[87],"these":[88],"limitations,":[89],"resulting":[90],"significant":[93],"performance":[94],"enhancement":[95],"approximately":[97],"2-24":[98],"times":[99],"compared":[100],"methods.":[103],"Our":[104],"computes":[106],"between":[110],"two":[111],"genomes,":[112],"each":[113],"comprising":[114],"1,000":[115],"letters,":[116],"just":[118],"few":[120],"seconds.":[121],"The":[122],"underlying":[123],"technique":[124,138],"our":[126],"novel":[130],"approach":[131],"transforms":[133],"established":[135],"approximate":[136],"matching":[137],"(i.e.,":[139],"Ukkonen":[141],"algorithm)":[142],"exact":[144],"matching,":[145],"exploiting":[146],"inherent":[148],"similarity":[149],"human":[151],"achieve":[154],"cost-effectiveness.":[155],"Furthermore,":[156],"various":[159],"optimizations":[160],"tailored":[161],"for":[162],"scenarios":[166],"with":[167],"limited":[169],"input":[170],"domain,":[171],"composed":[176],"solely":[177],"four":[180],"letters.":[182]},"counts_by_year":[],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}