{"id":"https://openalex.org/W7104661016","doi":"https://doi.org/10.5281/zenodo.17475543","title":"M-Ras Distinct Activation Scenarios: A Mechanistic Outlook and Targeting","display_name":"M-Ras Distinct Activation Scenarios: A Mechanistic Outlook and Targeting","publication_year":2025,"publication_date":"2025-10-29","ids":{"openalex":"https://openalex.org/W7104661016","doi":"https://doi.org/10.5281/zenodo.17475543"},"language":null,"primary_location":{"id":"doi:10.5281/zenodo.17475543","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.17475543","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dataset"},"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.17475543","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Xu, Liang","orcid":"https://orcid.org/0000-0002-6556-7521"},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Xu, Liang","raw_affiliation_strings":["Frederick National Laboratory for Cancer Research"],"raw_orcid":"https://orcid.org/0000-0002-6556-7521","affiliations":[{"raw_affiliation_string":"Frederick National Laboratory for Cancer Research","institution_ids":["https://openalex.org/I4210130649"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210130649"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":null,"topics":[],"keywords":[{"id":"https://openalex.org/keywords/microsecond","display_name":"Microsecond","score":0.4934000074863434},{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank (RCSB PDB)","score":0.45879998803138733},{"id":"https://openalex.org/keywords/trajectory","display_name":"Trajectory","score":0.42660000920295715},{"id":"https://openalex.org/keywords/replicate","display_name":"Replicate","score":0.3799999952316284},{"id":"https://openalex.org/keywords/key","display_name":"Key (lock)","score":0.27630001306533813}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6032000184059143},{"id":"https://openalex.org/C34742353","wikidata":"https://www.wikidata.org/wiki/Q842015","display_name":"Microsecond","level":2,"score":0.4934000074863434},{"id":"https://openalex.org/C65556437","wikidata":"https://www.wikidata.org/wiki/Q766195","display_name":"Protein Data Bank (RCSB PDB)","level":2,"score":0.45879998803138733},{"id":"https://openalex.org/C13662910","wikidata":"https://www.wikidata.org/wiki/Q193139","display_name":"Trajectory","level":2,"score":0.42660000920295715},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38670000433921814},{"id":"https://openalex.org/C2781162219","wikidata":"https://www.wikidata.org/wiki/Q26250693","display_name":"Replicate","level":2,"score":0.3799999952316284},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30480000376701355},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.27630001306533813},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2624000012874603},{"id":"https://openalex.org/C2781238097","wikidata":"https://www.wikidata.org/wiki/Q175026","display_name":"Object (grammar)","level":2,"score":0.2565000057220459}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5281/zenodo.17475543","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.17475543","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"dataset"}],"best_oa_location":{"id":"doi:10.5281/zenodo.17475543","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.17475543","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dataset"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"The":[0,31],"structure":[1],"and":[2,13,39],"trajectory":[3],"files":[4,34],"generaged":[5],"from":[6],"MD":[7],"simulations":[8,17],"of":[9],"M-Ras-GTP,":[10],"M-Ras-GDP,":[11],"M-Ras(Q71R)-GTP,":[12],"M-Ras(Q71R)-GDP.":[14],"Three":[15],"replicate":[16],"(each":[18],"200":[19],"frames":[20],"corresponding":[21],"to":[22,56],"2":[23],"microsecond":[24],"long)":[25],"were":[26],"performed":[27],"for":[28],"each":[29],"system.":[30],"representative":[32],"trajecory":[33],"are":[35],"in":[36],"PDB":[37],"format":[38],"can":[40],"be":[41],"viewed":[42],"by":[43],"many":[44],"programs":[45],"like":[46],"VMD.":[47],"Should":[48],"you":[49],"have":[50],"any":[51],"questions":[52],"please":[53],"reach":[54],"out":[55],"me":[57],"via":[58],"email:":[59],"liang.xu@nih.gov.":[60]},"counts_by_year":[],"updated_date":"2025-12-05T23:21:25.405358","created_date":"2025-11-11T00:00:00"}