{"id":"https://openalex.org/W6930687928","doi":"https://doi.org/10.5281/zenodo.15303191","title":"ML-Driven Localization of Infection Sources in the Human Cardiovascular System","display_name":"ML-Driven Localization of Infection Sources in the Human Cardiovascular System","publication_year":2025,"publication_date":"2025-04-30","ids":{"openalex":"https://openalex.org/W6930687928","doi":"https://doi.org/10.5281/zenodo.15303191"},"language":"en","primary_location":{"id":"doi:10.5281/zenodo.15303191","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.15303191","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dataset"},"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.15303191","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Pal, Saswati","orcid":"https://orcid.org/0000-0003-1218-4022"},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Pal, Saswati","raw_affiliation_strings":["Technische Universit\u00e4t Berlin"],"raw_orcid":"https://orcid.org/0000-0003-1218-4022","affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Berlin","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Torres G\u00f3mez, Jorge","orcid":null},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Torres G\u00f3mez, Jorge","raw_affiliation_strings":["Technische Universit\u00e4t Berlin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Berlin","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Debus, Lisa Yvonne","orcid":"https://orcid.org/0009-0002-2467-1813"},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Debus, Lisa Yvonne","raw_affiliation_strings":["Technische Universit\u00e4t Berlin"],"raw_orcid":"https://orcid.org/0009-0002-2467-1813","affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Berlin","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wendt, Regine","orcid":null},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wendt, Regine","raw_affiliation_strings":["University of L\u00fcbeck"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of L\u00fcbeck","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lau, Florian-Lennert","orcid":null},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lau, Florian-Lennert","raw_affiliation_strings":["University of L\u00fcbeck"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of L\u00fcbeck","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Khandanpour, Cyrus","orcid":null},"institutions":[{"id":"https://openalex.org/I4210112713","display_name":"University Hospital Schleswig-Holstein","ror":"https://ror.org/01tvm6f46","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210112713"]},{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Khandanpour, Cyrus","raw_affiliation_strings":["University Cancer Center Schleswig-Holstein"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Cancer Center Schleswig-Holstein","institution_ids":["https://openalex.org/I4210112713","https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sieren, Malte","orcid":null},"institutions":[{"id":"https://openalex.org/I4210112713","display_name":"University Hospital Schleswig-Holstein","ror":"https://ror.org/01tvm6f46","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210112713"]},{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sieren, Malte","raw_affiliation_strings":["University Cancer Center Schleswig-Holstein"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Cancer Center Schleswig-Holstein","institution_ids":["https://openalex.org/I4210112713","https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Fischer, Stefan","orcid":null},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fischer, Stefan","raw_affiliation_strings":["University of L\u00fcbeck"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of L\u00fcbeck","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"last","author":{"id":null,"display_name":"Dressler, Falko","orcid":"https://orcid.org/0000-0002-1989-1750"},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dressler, Falko","raw_affiliation_strings":["TU Berlin"],"raw_orcid":"https://orcid.org/0000-0002-1989-1750","affiliations":[{"raw_affiliation_string":"TU Berlin","institution_ids":["https://openalex.org/I4577782"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4577782"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10226","display_name":"Land Use and Ecosystem Services","score":0.7411999702453613,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10226","display_name":"Land Use and Ecosystem Services","score":0.7411999702453613,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10111","display_name":"Remote Sensing in Agriculture","score":0.018699999898672104,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12644","display_name":"Wildlife-Road Interactions and Conservation","score":0.012500000186264515,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leverage","display_name":"Leverage (statistics)","score":0.6604999899864197},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.6503000259399414},{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.6266999840736389},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.5803999900817871},{"id":"https://openalex.org/keywords/code","display_name":"Code (set theory)","score":0.36980000138282776},{"id":"https://openalex.org/keywords/infectious-disease","display_name":"Infectious disease (medical specialty)","score":0.3596999943256378},{"id":"https://openalex.org/keywords/profiling","display_name":"Profiling (computer programming)","score":0.35749998688697815}],"concepts":[{"id":"https://openalex.org/C153083717","wikidata":"https://www.wikidata.org/wiki/Q6535263","display_name":"Leverage (statistics)","level":2,"score":0.6604999899864197},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.6503000259399414},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.635699987411499},{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.6266999840736389},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5803999900817871},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4009000062942505},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38499999046325684},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.36980000138282776},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.3596999943256378},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.35749998688697815},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34450000524520874},{"id":"https://openalex.org/C41458344","wikidata":"https://www.wikidata.org/wiki/Q732577","display_name":"Publication","level":2,"score":0.34130001068115234},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.33230000734329224},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3197000026702881},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2906999886035919},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.2847000062465668},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.2840000092983246},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.2750999927520752},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26269999146461487},{"id":"https://openalex.org/C67186912","wikidata":"https://www.wikidata.org/wiki/Q367664","display_name":"Data modeling","level":2,"score":0.25609999895095825}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5281/zenodo.15303191","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.15303191","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"dataset"}],"best_oa_location":{"id":"doi:10.5281/zenodo.15303191","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.15303191","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dataset"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5860818028450012,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Short":[0],"Description":[1],"of":[2,8,33,58,150],"the":[3,30,56,67,119,128,139,161,165,169],"Paper":[4],"In":[5,20,46],"vivo":[6],"localization":[7],"infection":[9,43,54,86,155],"sources":[10,87,156],"is":[11],"essential":[12],"for":[13,108,160,180],"effective":[14],"diagnosis":[15],"and":[16,60,101,111,118,133,142,157],"targeted":[17],"disease":[18],"treatment.":[19],"this":[21],"work,":[22],"we":[23,48,71],"leverage":[24],"machine":[25],"learning":[26],"models":[27,53],"to":[28,80,103,122,184],"associate":[29],"temporal":[31,82],"dynamics":[32],"biomarkers":[34],"as":[35,63,125],"detected":[36],"at":[37,88],"static":[38],"gateway":[39,90],"positions":[40],"with":[41,76],"different":[42,85,154],"source":[44],"locations.":[45],"particular,":[47],"introduce":[49],"a":[50,95,135],"simulation":[51,116],"that":[52],"sources,":[55],"release":[57],"biomarkers,":[59],"their":[61],"decay":[62,78],"they":[64],"flow":[65],"through":[66],"bloodstream.":[68],"From":[69],"this,":[70],"extract":[72],"time-series":[73,106],"biomarker":[74,105,151],"data":[75,107,117],"varying":[77],"rates":[79],"capture":[81],"patterns":[83],"from":[84,153],"specific":[89],"positions.":[91],"We":[92,113],"then":[93],"train":[94],"stacked":[96],"ensemble":[97],"model":[98],"using":[99],"LightGBM":[100],"BernoulliNB":[102],"analyze":[104],"classification.":[109],"Data":[110],"Code":[112],"publish":[114],"our":[115],"Python":[120],"code":[121],"process":[123],"it":[124],"described":[126],"in":[127,134,168],"paper":[129],"here":[130],"on":[131],"Zenodo":[132],"GitHub":[136],"repository":[137],"under":[138],"CC":[140],"BY":[141],"MIT":[143],"licenses,":[144],"respectively.":[145],"Supplementary_Data.pdf":[146],"provides":[147],"an":[148],"overview":[149],"distributions":[152],"classification":[158],"results":[159,167],"70/30":[162],"split,":[163],"complementing":[164],"80/20":[166],"main":[170],"manuscript.":[171],"Contact":[172],"If":[173],"you":[174],"have":[175],"any":[176],"questions":[177],"or":[178],"suggestions":[179],"improvements,":[181],"feel":[182],"free":[183],"contact":[185],"me.":[186],"Saswati":[187],"Pal":[188],"Email:":[189],"pal@ccs-labs.org":[190]},"counts_by_year":[],"updated_date":"2025-11-06T06:51:31.235846","created_date":"2025-10-10T00:00:00"}