{"id":"https://openalex.org/W2344155150","doi":"https://doi.org/10.5220/0005659701590167","title":"A Coding Theoretical Approach to Predict Sequence Changes in H5N1 Influenza A Virus Hemagglutinin","display_name":"A Coding Theoretical Approach to Predict Sequence Changes in H5N1 Influenza A Virus Hemagglutinin","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2344155150","doi":"https://doi.org/10.5220/0005659701590167","mag":"2344155150"},"language":"en","primary_location":{"id":"doi:10.5220/0005659701590167","is_oa":false,"landing_page_url":"https://doi.org/10.5220/0005659701590167","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041771235","display_name":"Keiko Sato","orcid":"https://orcid.org/0000-0003-0226-1338"},"institutions":[{"id":"https://openalex.org/I161296585","display_name":"Tokyo University of Science","ror":"https://ror.org/05sj3n476","country_code":"JP","type":"education","lineage":["https://openalex.org/I161296585"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Keiko Sato","raw_affiliation_strings":["Tokyo Univiersity of Science, Japan"],"affiliations":[{"raw_affiliation_string":"Tokyo Univiersity of Science, Japan","institution_ids":["https://openalex.org/I161296585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112257279","display_name":"Toshihide Hara","orcid":null},"institutions":[{"id":"https://openalex.org/I161296585","display_name":"Tokyo University of Science","ror":"https://ror.org/05sj3n476","country_code":"JP","type":"education","lineage":["https://openalex.org/I161296585"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshihide Hara","raw_affiliation_strings":["Tokyo Univiersity of Science, Japan"],"affiliations":[{"raw_affiliation_string":"Tokyo Univiersity of Science, Japan","institution_ids":["https://openalex.org/I161296585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113861389","display_name":"Masanori Ohya","orcid":null},"institutions":[{"id":"https://openalex.org/I161296585","display_name":"Tokyo University of Science","ror":"https://ror.org/05sj3n476","country_code":"JP","type":"education","lineage":["https://openalex.org/I161296585"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanori Ohya","raw_affiliation_strings":["Tokyo Univiersity of Science, Japan"],"affiliations":[{"raw_affiliation_string":"Tokyo Univiersity of Science, Japan","institution_ids":["https://openalex.org/I161296585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5041771235"],"corresponding_institution_ids":["https://openalex.org/I161296585"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04150379,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"159","last_page":"167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9923999905586243,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/influenza-a-virus-subtype-h5n1","display_name":"Influenza A virus subtype H5N1","score":0.7795815467834473},{"id":"https://openalex.org/keywords/hemagglutinin","display_name":"Hemagglutinin (influenza)","score":0.7334624528884888},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5871288776397705},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.5275810956954956},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5143605470657349},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.4732765853404999},{"id":"https://openalex.org/keywords/influenza-a-virus","display_name":"Influenza A virus","score":0.45488572120666504},{"id":"https://openalex.org/keywords/coding-region","display_name":"Coding region","score":0.43896251916885376},{"id":"https://openalex.org/keywords/peptide-sequence","display_name":"Peptide sequence","score":0.42209771275520325},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.36623018980026245},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.359164834022522},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.14474818110466003}],"concepts":[{"id":"https://openalex.org/C519248777","wikidata":"https://www.wikidata.org/wiki/Q160122","display_name":"Influenza A virus subtype H5N1","level":3,"score":0.7795815467834473},{"id":"https://openalex.org/C2778692840","wikidata":"https://www.wikidata.org/wiki/Q9136673","display_name":"Hemagglutinin (influenza)","level":3,"score":0.7334624528884888},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5871288776397705},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5275810956954956},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5143605470657349},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4732765853404999},{"id":"https://openalex.org/C2777546802","wikidata":"https://www.wikidata.org/wiki/Q834390","display_name":"Influenza A virus","level":3,"score":0.45488572120666504},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.43896251916885376},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.42209771275520325},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.36623018980026245},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.359164834022522},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14474818110466003}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5220/0005659701590167","is_oa":false,"landing_page_url":"https://doi.org/10.5220/0005659701590167","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W198054361","https://openalex.org/W2124103225","https://openalex.org/W4391064179","https://openalex.org/W4283763648","https://openalex.org/W1556716938","https://openalex.org/W3030201000","https://openalex.org/W2013097789","https://openalex.org/W2336164517","https://openalex.org/W2949346453","https://openalex.org/W4380729957"],"abstract_inverted_index":{"The":[0],"changes":[1,207],"in":[2,52,111,121,131,149,197,208,218],"the":[3,14,22,27,49,53,56,71,87,91,96,128,132,150,158,166,170,174,183,186,190,209,219,227,237],"receptor":[4,57,133],"binding":[5,58,134],"domain":[6,135],"of":[7,16,30,55,61,68,74,90,103,127,136,169,192,199,212,226,230,239],"influenza":[8,37,231],"A":[9,232],"virus":[10],"hemagglutinin":[11,160],"lead":[12],"to":[13,78,85,124],"appearance":[15],"new":[17,240],"viral":[18],"strains":[19,38,214],"that":[20,46,165,182,215],"evade":[21],"immune":[23],"system.":[24],"To":[25],"prepare":[26],"future":[28],"emergence":[29],"potentially":[31],"dangerous":[32],"outbreaks":[33],"caused":[34],"by":[35],"divergent":[36],"including":[39],"human-adapted":[40],"H5N1":[41,213],"strains,":[42],"it":[43],"is":[44,63,83],"imperative":[45],"we":[47,94,99,117,163,202],"understand":[48],"rule":[50],"stored":[51,64],"sequence":[54,67,72,125],"domain.":[59],"Information":[60],"life":[62,112],"as":[65],"a":[66,80],"nucleotides,":[69],"and":[70,140,234,243],"composed":[73],"four":[75],"nucleotides":[76],"seems":[77],"be":[79],"code.":[81],"It":[82],"important":[84],"determine":[86],"code":[88,97,167],"structure":[89,168,191],"sequences.":[92],"Once":[93],"know":[95],"structure,":[98],"can":[100],"make":[101],"use":[102],"mathematical":[104],"results":[105,180],"concerning":[106],"coding":[107,122],"theory":[108,123],"for":[109],"research":[110],"science.":[113],"In":[114,195],"this":[115],"study,":[116],"applied":[118],"various":[119],"codes":[120],"analysis":[126],"220":[129,151,171,187,210],"loop":[130,152,172,188,211],"H1,":[137],"H3,":[138],"H5":[139],"H7":[141],"subtype":[142,176],"viruses":[143],"isolated":[144],"from":[145,173],"humans.":[146],"Sequence":[147],"diversity":[148],"has":[153],"been":[154],"observed":[155],"even":[156],"within":[157],"same":[159,175],"subtype.":[161],"However,":[162],"found":[164],"remains":[177],"unchanged.":[178],"Our":[179,221],"indicate":[181],"sequences":[184],"at":[185],"have":[189],"subtype-specific":[193],"codes.":[194],"addition,":[196],"view":[198],"these":[200],"finding,":[201],"predicted":[203],"possible":[204],"amino":[205],"acid":[206],"will":[216,223],"emerge":[217],"future.":[220],"method":[222],"facilitate":[224],"understanding":[225],"evolutionary":[228],"patterns":[229],"viruses,":[233],"further":[235],"help":[236],"development":[238],"antiviral":[241],"drugs":[242],"vaccines.":[244]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}