{"id":"https://openalex.org/W7160521936","doi":"https://doi.org/10.48550/arxiv.2605.04908","title":"Curated AI beats frontier LLMs at pharma asset discovery","display_name":"Curated AI beats frontier LLMs at pharma asset discovery","publication_year":2026,"publication_date":"2026-05-06","ids":{"openalex":"https://openalex.org/W7160521936","doi":"https://doi.org/10.48550/arxiv.2605.04908"},"language":null,"primary_location":{"id":"doi:10.48550/arxiv.2605.04908","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2605.04908","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"},"type":"preprint","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.48550/arxiv.2605.04908","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026101553","display_name":"\u0141ukasz Kidzi\u0144ski","orcid":"https://orcid.org/0000-0002-0986-3078"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kidzi\u0144ski, \u0141ukasz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5135564004","display_name":"Kevin Thomas","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas, Kevin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.6746000051498413,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.6746000051498413,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.1242000013589859,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.04340000078082085,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/index","display_name":"Index (typography)","score":0.6211000084877014},{"id":"https://openalex.org/keywords/json","display_name":"JSON","score":0.5600000023841858},{"id":"https://openalex.org/keywords/frontier","display_name":"Frontier","score":0.5094000101089478},{"id":"https://openalex.org/keywords/asset","display_name":"Asset (computer security)","score":0.4887000024318695},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.4641999900341034},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.41190001368522644},{"id":"https://openalex.org/keywords/javascript","display_name":"JavaScript","score":0.38909998536109924},{"id":"https://openalex.org/keywords/web-service","display_name":"Web service","score":0.3506999909877777},{"id":"https://openalex.org/keywords/european-union","display_name":"European union","score":0.34380000829696655}],"concepts":[{"id":"https://openalex.org/C2777382242","wikidata":"https://www.wikidata.org/wiki/Q6017816","display_name":"Index (typography)","level":2,"score":0.6211000084877014},{"id":"https://openalex.org/C2780416260","wikidata":"https://www.wikidata.org/wiki/Q2063","display_name":"JSON","level":2,"score":0.5600000023841858},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.538100004196167},{"id":"https://openalex.org/C2778571376","wikidata":"https://www.wikidata.org/wiki/Q1355821","display_name":"Frontier","level":2,"score":0.5094000101089478},{"id":"https://openalex.org/C76178495","wikidata":"https://www.wikidata.org/wiki/Q4808784","display_name":"Asset (computer security)","level":2,"score":0.4887000024318695},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.4702000021934509},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.4641999900341034},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.41190001368522644},{"id":"https://openalex.org/C544833334","wikidata":"https://www.wikidata.org/wiki/Q2005","display_name":"JavaScript","level":2,"score":0.38909998536109924},{"id":"https://openalex.org/C35578498","wikidata":"https://www.wikidata.org/wiki/Q193424","display_name":"Web service","level":2,"score":0.3506999909877777},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.3474000096321106},{"id":"https://openalex.org/C2910001868","wikidata":"https://www.wikidata.org/wiki/Q458","display_name":"European union","level":2,"score":0.34380000829696655},{"id":"https://openalex.org/C2779099944","wikidata":"https://www.wikidata.org/wiki/Q4693571","display_name":"Agora","level":2,"score":0.3321000039577484},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3179999887943268},{"id":"https://openalex.org/C81669768","wikidata":"https://www.wikidata.org/wiki/Q2359161","display_name":"Precision and recall","level":2,"score":0.3028999865055084},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.29899999499320984},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.2971999943256378},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.2937000095844269},{"id":"https://openalex.org/C65603577","wikidata":"https://www.wikidata.org/wiki/Q3427877","display_name":"Web resource","level":2,"score":0.2930999994277954},{"id":"https://openalex.org/C55166926","wikidata":"https://www.wikidata.org/wiki/Q2892946","display_name":"Oracle","level":2,"score":0.290800005197525},{"id":"https://openalex.org/C8797682","wikidata":"https://www.wikidata.org/wiki/Q2115","display_name":"XML","level":2,"score":0.2906000018119812},{"id":"https://openalex.org/C89505385","wikidata":"https://www.wikidata.org/wiki/Q47146","display_name":"User interface","level":2,"score":0.2883000075817108},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.2831000089645386},{"id":"https://openalex.org/C99138194","wikidata":"https://www.wikidata.org/wiki/Q183427","display_name":"Hash function","level":2,"score":0.2711000144481659},{"id":"https://openalex.org/C2778869765","wikidata":"https://www.wikidata.org/wiki/Q6028363","display_name":"Inefficiency","level":2,"score":0.26420000195503235},{"id":"https://openalex.org/C11392498","wikidata":"https://www.wikidata.org/wiki/Q11288","display_name":"Web server","level":3,"score":0.2630000114440918},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.25859999656677246},{"id":"https://openalex.org/C118643609","wikidata":"https://www.wikidata.org/wiki/Q189210","display_name":"Web application","level":2,"score":0.2574000060558319},{"id":"https://openalex.org/C51485801","wikidata":"https://www.wikidata.org/wiki/Q16966861","display_name":"Efficient frontier","level":3,"score":0.25609999895095825},{"id":"https://openalex.org/C100279451","wikidata":"https://www.wikidata.org/wiki/Q372193","display_name":"Perplexity","level":3,"score":0.2542000114917755},{"id":"https://openalex.org/C4216890","wikidata":"https://www.wikidata.org/wiki/Q815823","display_name":"Business model","level":2,"score":0.25}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.48550/arxiv.2605.04908","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2605.04908","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"doi:10.48550/arxiv.2605.04908","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2605.04908","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.5310842990875244,"display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"General-purpose":[0],"LLMs":[1],"with":[2,23,41],"web":[3,42,153],"search":[4,154],"are":[5],"increasingly":[6],"used":[7],"to":[8],"scout":[9],"the":[10,62,66,78,83,100,111,147,160],"competitive":[11],"landscape":[12],"of":[13,61,69,114,140,146],"pharmaceutical":[14],"pipelines.":[15],"We":[16],"benchmark":[17],"Gosset":[18,91,125],"--":[19,36],"an":[20],"AI":[21],"platform":[22],"a":[24,124,135,156],"chat":[25,162],"interface":[26],"backed":[27],"by":[28,150],"curated":[29,119,157],"target-,":[30],"modality-,":[31],"and":[32,71,82,107],"indication-level":[33],"drug-asset":[34],"annotations":[35],"against":[37,110],"four":[38],"frontier":[39,102,130],"systems":[40,76,142],"access":[43],"(Claude":[44],"Opus":[45],"4.7,":[46],"GPT":[47],"5.5,":[48],"Gemini":[49],"3.1":[50],"Pro,":[51],"Perplexity":[52],"sonar-pro)":[53],"on":[54],"ten":[55],"niche":[56],"oncology/immunology":[57],"targets":[58,90],"where":[59],"most":[60,145],"pipeline":[63],"lives":[64],"in":[65],"long":[67],"tail":[68],"preclinical":[70],"Asian-developed":[72],"assets.":[73],"All":[74],"five":[75],"receive":[77],"same":[79,84,118,161],"natural-language":[80],"query":[81,98],"JSON":[85],"output":[86],"schema.":[87],"Across":[88],"10":[89],"returns":[92],"3.2x":[93],"more":[94],"verified":[95,115],"drugs":[96],"per":[97],"than":[99],"best":[101],"system,":[103],"at":[104],"perfect":[105],"precision":[106],"100%":[108],"recall":[109,148],"cross-system":[112],"union":[113],"drugs.":[116],"The":[117],"index":[120,158],"is":[121],"exposed":[122],"as":[123,134],"MCP":[126],"server":[127],"that":[128,138],"any":[129],"model":[131],"can":[132,143],"call":[133],"tool,":[136],"suggesting":[137],"each":[139],"these":[141],"close":[144],"gap":[149],"swapping":[151],"generic":[152],"for":[155],"behind":[159],"interface.":[163]},"counts_by_year":[],"updated_date":"2026-07-01T06:00:48.157686","created_date":"2026-05-08T00:00:00"}