{"id":"https://openalex.org/W7131232095","doi":"https://doi.org/10.48550/arxiv.2602.18715","title":"A Data-Driven Method to Map the Functional Organisation of Human Brain White Matter","display_name":"A Data-Driven Method to Map the Functional Organisation of Human Brain White Matter","publication_year":2026,"publication_date":"2026-02-21","ids":{"openalex":"https://openalex.org/W7131232095","doi":"https://doi.org/10.48550/arxiv.2602.18715"},"language":null,"primary_location":{"id":"pmh:doi:10.48550/arxiv.2602.18715","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"publisher-specific-oa","license_id":"https://openalex.org/licenses/publisher-specific-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},"type":"preprint","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":null,"any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5126683020","display_name":"Yifei Sun","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sun, Yifei","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126719380","display_name":"James M. Shine","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shine, James M.","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121653608","display_name":"Robert D. Sanders","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sanders, Robert D.","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121747830","display_name":"Robin F. H. Cash","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cash, Robin F. H.","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077825658","display_name":"Sharon L. Naismith","orcid":"https://orcid.org/0000-0001-9076-2778"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Naismith, Sharon L.","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071212566","display_name":"Fernando Calamante","orcid":"https://orcid.org/0000-0002-7550-3142"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Calamante, Fernando","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5126666063","display_name":"Jinglei Lv","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lv, Jinglei","raw_affiliation_strings":[],"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5126683020"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/white-matter","display_name":"White matter","score":0.864799976348877},{"id":"https://openalex.org/keywords/human-connectome-project","display_name":"Human Connectome Project","score":0.7818999886512756},{"id":"https://openalex.org/keywords/grey-matter","display_name":"Grey matter","score":0.6603999733924866},{"id":"https://openalex.org/keywords/human-brain","display_name":"Human brain","score":0.6322000026702881},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.5485000014305115},{"id":"https://openalex.org/keywords/diffusion-imaging","display_name":"Diffusion imaging","score":0.4945000112056732},{"id":"https://openalex.org/keywords/connectome","display_name":"Connectome","score":0.49399998784065247},{"id":"https://openalex.org/keywords/brain-mapping","display_name":"Brain mapping","score":0.4887999892234802},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.48429998755455017}],"concepts":[{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.864799976348877},{"id":"https://openalex.org/C97820695","wikidata":"https://www.wikidata.org/wiki/Q387749","display_name":"Human Connectome Project","level":3,"score":0.7818999886512756},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6958000063896179},{"id":"https://openalex.org/C2778013878","wikidata":"https://www.wikidata.org/wiki/Q646150","display_name":"Grey matter","level":4,"score":0.6603999733924866},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.6322000026702881},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5485000014305115},{"id":"https://openalex.org/C2992283565","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion imaging","level":4,"score":0.4945000112056732},{"id":"https://openalex.org/C45715564","wikidata":"https://www.wikidata.org/wiki/Q1292103","display_name":"Connectome","level":3,"score":0.49399998784065247},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.4887999892234802},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.48429998755455017},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.47839999198913574},{"id":"https://openalex.org/C2993410155","wikidata":"https://www.wikidata.org/wiki/Q5508841","display_name":"Functional organization","level":2,"score":0.4478999972343445},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.3984000086784363},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.391400009393692},{"id":"https://openalex.org/C101812284","wikidata":"https://www.wikidata.org/wiki/Q2450135","display_name":"Functional integration","level":3,"score":0.3833000063896179},{"id":"https://openalex.org/C182752723","wikidata":"https://www.wikidata.org/wiki/Q1474590","display_name":"Functional imaging","level":2,"score":0.365200012922287},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3467999994754791},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.33719998598098755},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.3174000084400177},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3084000051021576},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.3077999949455261},{"id":"https://openalex.org/C107968991","wikidata":"https://www.wikidata.org/wiki/Q1868509","display_name":"Functional specialization","level":2,"score":0.30480000376701355},{"id":"https://openalex.org/C84787856","wikidata":"https://www.wikidata.org/wiki/Q3076659","display_name":"Tractography","level":4,"score":0.2802000045776367},{"id":"https://openalex.org/C2986219828","wikidata":"https://www.wikidata.org/wiki/Q1193095","display_name":"Coupling strength","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C172467417","wikidata":"https://www.wikidata.org/wiki/Q1670397","display_name":"Neurocognitive","level":3,"score":0.2752000093460083},{"id":"https://openalex.org/C141516989","wikidata":"https://www.wikidata.org/wiki/Q1182555","display_name":"Default mode network","level":3,"score":0.2734000086784363},{"id":"https://openalex.org/C140530291","wikidata":"https://www.wikidata.org/wiki/Q1225063","display_name":"Dorsum","level":2,"score":0.25760000944137573},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.257099986076355},{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.2549000084400177}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:doi:10.48550/arxiv.2602.18715","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"publisher-specific-oa","license_id":"https://openalex.org/licenses/publisher-specific-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"doi:10.48550/arxiv.2602.18715","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2602.18715","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:doi:10.48550/arxiv.2602.18715","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"publisher-specific-oa","license_id":"https://openalex.org/licenses/publisher-specific-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"The":[0],"white":[1,29,59,81,97,159],"matter":[2,30,60,77,82,98,160],"of":[3,23,74,96,158],"the":[4,54,101,111,144,155],"brain":[5,169],"is":[6],"organised":[7],"into":[8],"axonal":[9],"bundles":[10],"that":[11,45],"support":[12],"long-range":[13],"neural":[14,35],"communication.":[15],"Although":[16],"diffusion":[17],"MRI":[18,50],"(dMRI)":[19],"enables":[20],"detailed":[21],"mapping":[22],"these":[24,115,152],"pathways":[25,31,133],"through":[26],"tractography,":[27],"how":[28],"directly":[32],"facilitate":[33],"large-scale":[34],"synchronisation":[36],"remains":[37],"poorly":[38],"understood.":[39],"We":[40],"developed":[41],"a":[42,164],"data-driven":[43],"framework":[44],"integrates":[46],"dMRI":[47],"and":[48,126,139,148,162,171],"functional":[49,67,72,123,156],"(fMRI)":[51],"to":[52,70,110,167],"model":[53],"dynamic":[55,66],"coupling":[56,73,124],"supported":[57],"by":[58,79,89],"tracks.":[61,83],"Specifically,":[62],"we":[63,92],"employed":[64],"track":[65],"connectivity":[68],"(Track-DFC)":[69],"characterise":[71],"remote":[75],"grey":[76],"connected":[78],"individual":[80],"Using":[84],"independent":[85],"component":[86],"analysis":[87],"followed":[88],"k-medoids":[90],"clustering,":[91],"derived":[93],"functionally-coherent":[94],"clusters":[95,116,131],"tracks":[99,161],"from":[100],"Human":[102],"Connectome":[103],"Project":[104],"young":[105],"adult":[106],"cohort.":[107],"When":[108],"applied":[109],"HCP":[112],"ageing":[113,170],"cohort,":[114],"exhibited":[117],"widespread":[118],"age-related":[119],"declines":[120],"in":[121],"both":[122],"strength":[125],"temporal":[127],"variability.":[128],"Importantly,":[129],"specific":[130],"encompassing":[132],"linking":[134],"control,":[135],"default":[136],"mode,":[137],"attention,":[138],"visual":[140],"systems":[141],"significantly":[142],"mediated":[143],"relationship":[145],"between":[146],"age":[147],"cognitive":[149,172],"performance.":[150],"Together,":[151],"findings":[153],"depict":[154],"organisation":[157],"provide":[163],"powerful":[165],"tool":[166],"study":[168],"decline.":[173]},"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2026-02-25T00:00:00"}