{"id":"https://openalex.org/W7128022391","doi":"https://doi.org/10.48550/arxiv.2602.03881","title":"DiGAN: Diffusion-Guided Attention Network for Early Alzheimer's Disease Detection","display_name":"DiGAN: Diffusion-Guided Attention Network for Early Alzheimer's Disease Detection","publication_year":2026,"publication_date":"2026-02-02","ids":{"openalex":"https://openalex.org/W7128022391","doi":"https://doi.org/10.48550/arxiv.2602.03881"},"language":null,"primary_location":{"id":"pmh:doi:10.48550/arxiv.2602.03881","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},"type":"preprint","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":null,"any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052219753","display_name":"Maxx Richard Rahman","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rahman, Maxx Richard","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125178212","display_name":"Mostafa Hammouda","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hammouda, Mostafa","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5043339871","display_name":"Wolfgang Maass","orcid":"https://orcid.org/0000-0002-1178-087X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maass, Wolfgang","raw_affiliation_strings":[],"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5052219753"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.3077999949455261,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.3077999949455261,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.275299996137619,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11307","display_name":"Domain Adaptation and Few-Shot Learning","score":0.08399999886751175,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.6639999747276306},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.6337000131607056},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.5498999953269958},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.5149999856948853},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.47589999437332153},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.4180000126361847},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.3880999982357025}],"concepts":[{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.6639999747276306},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.6337000131607056},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6136000156402588},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5889000296592712},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.5498999953269958},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5149999856948853},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.47589999437332153},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.4180000126361847},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.41370001435279846},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.3880999982357025},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.34540000557899475},{"id":"https://openalex.org/C2780226545","wikidata":"https://www.wikidata.org/wiki/Q6888030","display_name":"Modality (human\u2013computer interaction)","level":2,"score":0.3310999870300293},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.33059999346733093},{"id":"https://openalex.org/C141516989","wikidata":"https://www.wikidata.org/wiki/Q1182555","display_name":"Default mode network","level":3,"score":0.30799999833106995},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3010999858379364},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2973000109195709},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.28839999437332153},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.28119999170303345},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.2720000147819519},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.2540000081062317}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:doi:10.48550/arxiv.2602.03881","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"doi:10.48550/arxiv.2602.03881","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2602.03881","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:doi:10.48550/arxiv.2602.03881","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.7840477228164673}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Early":[0],"diagnosis":[1],"of":[2,18],"Alzheimer's":[3],"disease":[4],"(AD)":[5],"remains":[6],"a":[7],"major":[8],"challenge":[9],"due":[10],"to":[11,37,89],"the":[12,23,39,56,118],"subtle":[13],"and":[14,34,42,86,112],"temporally":[15],"irregular":[16],"progression":[17],"structural":[19],"brain":[20],"changes":[21],"in":[22,46],"prodromal":[24],"stages.":[25],"Existing":[26],"deep":[27],"learning":[28],"approaches":[29],"require":[30],"large":[31],"longitudinal":[32,76],"datasets":[33],"often":[35],"fail":[36],"model":[38,73],"temporal":[40,84],"continuity":[41],"modality":[43],"irregularities":[44],"inherent":[45],"real-world":[47],"clinical":[48],"data.":[49],"To":[50],"address":[51],"these":[52],"limitations,":[53],"we":[54],"propose":[55],"Diffusion-Guided":[57],"Attention":[58],"Network":[59],"(DiGAN),":[60],"which":[61],"integrates":[62],"latent":[63],"diffusion":[64,72],"modelling":[65],"with":[66,108],"an":[67],"attention-guided":[68],"convolutional":[69],"network.":[70],"The":[71,93],"synthesizes":[74],"realistic":[75],"neuroimaging":[77],"trajectories":[78],"from":[79,106],"limited":[80],"training":[81],"data,":[82],"enriching":[83],"context":[85],"improving":[87],"robustness":[88],"unevenly":[90],"spaced":[91],"visits.":[92],"attention-convolutional":[94],"layer":[95],"then":[96],"captures":[97],"discriminative":[98],"structural-temporal":[99],"patterns":[100],"that":[101,122],"distinguish":[102],"cognitively":[103],"normal":[104],"subjects":[105],"those":[107],"mild":[109],"cognitive":[110,114],"impairment":[111],"subjective":[113],"decline.":[115],"Experiments":[116],"on":[117],"ADNI":[119],"dataset":[120],"demonstrate":[121],"DiGAN":[123],"outperforms":[124],"existing":[125],"state-of-the-art":[126],"baselines,":[127],"showing":[128],"its":[129],"potential":[130],"for":[131],"early-stage":[132],"AD":[133],"detection.":[134]},"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2026-02-07T00:00:00"}