{"id":"https://openalex.org/W4417174946","doi":"https://doi.org/10.48550/arxiv.2507.01081","title":"AI-guided digital intervention with physiological monitoring reduces intrusive memories after experimental trauma","display_name":"AI-guided digital intervention with physiological monitoring reduces intrusive memories after experimental trauma","publication_year":2025,"publication_date":"2025-07-01","ids":{"openalex":"https://openalex.org/W4417174946","doi":"https://doi.org/10.48550/arxiv.2507.01081"},"language":"en","primary_location":{"id":"pmh:oai:arXiv.org:2507.01081","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2507.01081","pdf_url":"https://arxiv.org/pdf/2507.01081","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"type":"preprint","indexed_in":["arxiv","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2507.01081","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120735731","display_name":"Megan T. deBettencourt","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"deBettencourt, Megan T.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120759035","display_name":"Sruthi Sakthivel","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sakthivel, Sruthi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Holmes, Emily A.","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Holmes, Emily A.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5120735732","display_name":"Mark Chevillet","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chevillet, Mark","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.384799987077713,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.384799987077713,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.1266999989748001,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.04450000077486038,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intervention","display_name":"Intervention (counseling)","score":0.6632999777793884},{"id":"https://openalex.org/keywords/psychological-intervention","display_name":"Psychological intervention","score":0.4603999853134155},{"id":"https://openalex.org/keywords/pupillometry","display_name":"Pupillometry","score":0.387800008058548},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.37929999828338623},{"id":"https://openalex.org/keywords/brief-intervention","display_name":"Brief intervention","score":0.3781999945640564},{"id":"https://openalex.org/keywords/test","display_name":"Test (biology)","score":0.3425000011920929},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.3407999873161316}],"concepts":[{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.6632999777793884},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4763999879360199},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.4603999853134155},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44040000438690186},{"id":"https://openalex.org/C2778711042","wikidata":"https://www.wikidata.org/wiki/Q3410891","display_name":"Pupillometry","level":3,"score":0.387800008058548},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.37929999828338623},{"id":"https://openalex.org/C2776436463","wikidata":"https://www.wikidata.org/wiki/Q4967030","display_name":"Brief intervention","level":3,"score":0.3781999945640564},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3725000023841858},{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.3425000011920929},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3407999873161316},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.33880001306533813},{"id":"https://openalex.org/C111640148","wikidata":"https://www.wikidata.org/wiki/Q847349","display_name":"Rubric","level":2,"score":0.32820001244544983},{"id":"https://openalex.org/C149288182","wikidata":"https://www.wikidata.org/wiki/Q7260673","display_name":"Pupillary response","level":3,"score":0.3118000030517578},{"id":"https://openalex.org/C175154964","wikidata":"https://www.wikidata.org/wiki/Q380077","display_name":"Task analysis","level":3,"score":0.2856999933719635},{"id":"https://openalex.org/C2778476105","wikidata":"https://www.wikidata.org/wiki/Q628539","display_name":"Workload","level":2,"score":0.2847000062465668},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.26759999990463257},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.2587999999523163},{"id":"https://openalex.org/C2780732545","wikidata":"https://www.wikidata.org/wiki/Q7315969","display_name":"Response to intervention","level":3,"score":0.25290000438690186},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.25200000405311584},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.2517000138759613}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:arXiv.org:2507.01081","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2507.01081","pdf_url":"https://arxiv.org/pdf/2507.01081","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.2507.01081","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2507.01081","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2507.01081","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2507.01081","pdf_url":"https://arxiv.org/pdf/2507.01081","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Trauma":[0],"prevalence":[1],"is":[2],"vast":[3],"globally.":[4],"Evidence-based":[5],"digital":[6,54,142],"treatments":[7],"can":[8,145],"help,":[9],"but":[10,26],"most":[11],"require":[12],"human":[13],"guidance.":[14],"Human":[15],"guides":[16],"provide":[17,34],"tailored":[18],"instructions":[19],"and":[20,32,45,50,81,123],"responsiveness":[21],"to":[22,47,63,76,84,147],"internal":[23],"cognitive":[24],"states,":[25],"limit":[27],"scalability.":[28],"Can":[29],"generative":[30],"AI":[31,43,111],"neurotechnology":[33],"a":[35,128,137],"scalable":[36],"alternative?":[37],"Here":[38],"we":[39],"test":[40],"ANTIDOTE,":[41],"combining":[42],"guidance":[44],"pupillometry":[46],"automatically":[48],"deliver":[49],"monitor":[51],"an":[52,85],"evidence-based":[53],"treatment,":[55],"specifically":[56],"the":[57,101,110,114],"Imagery":[58],"Competing":[59],"Task":[60],"Intervention":[61],"(ICTI),":[62],"reduce":[64],"intrusive":[65,98],"memories":[66,99],"after":[67],"psychological":[68],"trauma.":[69],"One":[70],"hundred":[71],"healthy":[72],"volunteers":[73],"were":[74],"exposed":[75],"videos":[77],"of":[78,131],"traumatic":[79],"events":[80],"randomly":[82],"assigned":[83],"intervention":[86,93,115,121,132],"or":[87],"active":[88],"control":[89],"condition.":[90],"As":[91],"predicted,":[92],"participants":[94],"reported":[95],"significantly":[96],"fewer":[97],"over":[100],"following":[102],"week.":[103],"Post-hoc":[104],"assessment":[105],"against":[106],"clinical":[107],"rubrics":[108],"confirmed":[109],"guide":[112],"delivered":[113],"successfully.":[116],"Additionally,":[117],"pupil":[118],"size":[119],"tracked":[120],"engagement":[122],"predicted":[124],"symptom":[125],"reduction,":[126],"providing":[127],"candidate":[129],"biomarker":[130],"effectiveness.":[133],"These":[134],"findings":[135],"open":[136],"path":[138],"toward":[139],"rigorous":[140],"AI-guided":[141],"interventions":[143],"that":[144],"scale":[146],"trauma":[148],"prevalence.":[149]},"counts_by_year":[],"updated_date":"2026-08-05T07:39:15.569665","created_date":"2025-10-10T00:00:00"}