{"id":"https://openalex.org/W6967167055","doi":"https://doi.org/10.48550/arxiv.2407.14668","title":"Towards a \"universal translator\" for neural dynamics at single-cell, single-spike resolution","display_name":"Towards a \"universal translator\" for neural dynamics at single-cell, single-spike resolution","publication_year":2024,"publication_date":"2024-07-19","ids":{"openalex":"https://openalex.org/W6967167055","doi":"https://doi.org/10.48550/arxiv.2407.14668"},"language":"en","primary_location":{"id":"pmh:oai:arXiv.org:2407.14668","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2407.14668","pdf_url":"https://arxiv.org/pdf/2407.14668","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},"type":"preprint","indexed_in":["arxiv","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2407.14668","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Zhang, Yizi","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Zhang, Yizi","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Wang, Yanchen","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wang, Yanchen","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jimenez-Beneto, Donato","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jimenez-Beneto, Donato","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Wang, Zixuan","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wang, Zixuan","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Azabou, Mehdi","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Azabou, Mehdi","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Richards, Blake","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richards, Blake","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Winter, Olivier","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Winter, Olivier","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Laboratory, International Brain","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laboratory, International Brain","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Dyer, Eva","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dyer, Eva","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Paninski, Liam","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paninski, Liam","raw_affiliation_strings":[],"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Hurwitz, Cole","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hurwitz, Cole","raw_affiliation_strings":[],"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":11,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.07050000131130219,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.030300000682473183,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nucleofection","display_name":"Nucleofection","score":0.34709998965263367},{"id":"https://openalex.org/keywords/hyporeflexia","display_name":"Hyporeflexia","score":0.30090001225471497},{"id":"https://openalex.org/keywords/tsg101","display_name":"TSG101","score":0.29809999465942383},{"id":"https://openalex.org/keywords/gestational-period","display_name":"Gestational period","score":0.25780001282691956},{"id":"https://openalex.org/keywords/tubulopathy","display_name":"Tubulopathy","score":0.2535000145435333},{"id":"https://openalex.org/keywords/articular-cartilage-damage","display_name":"Articular cartilage damage","score":0.2533999979496002}],"concepts":[{"id":"https://openalex.org/C144251240","wikidata":"https://www.wikidata.org/wiki/Q7068229","display_name":"Nucleofection","level":4,"score":0.34709998965263367},{"id":"https://openalex.org/C2777158700","wikidata":"https://www.wikidata.org/wiki/Q1419356","display_name":"Hyporeflexia","level":3,"score":0.30090001225471497},{"id":"https://openalex.org/C2778283623","wikidata":"https://www.wikidata.org/wiki/Q18032200","display_name":"TSG101","level":5,"score":0.29809999465942383},{"id":"https://openalex.org/C2992336715","wikidata":"https://www.wikidata.org/wiki/Q63431143","display_name":"Gestational period","level":4,"score":0.25780001282691956},{"id":"https://openalex.org/C2776356786","wikidata":"https://www.wikidata.org/wiki/Q1048573","display_name":"Tubulopathy","level":3,"score":0.2535000145435333},{"id":"https://openalex.org/C2781032047","wikidata":"https://www.wikidata.org/wiki/Q938793","display_name":"Articular cartilage damage","level":5,"score":0.2533999979496002},{"id":"https://openalex.org/C2777054765","wikidata":"https://www.wikidata.org/wiki/Q6402731","display_name":"Dysgeusia","level":3,"score":0.2517000138759613},{"id":"https://openalex.org/C145741570","wikidata":"https://www.wikidata.org/wiki/Q7251534","display_name":"Proteogenomics","level":5,"score":0.24889999628067017},{"id":"https://openalex.org/C18743360","wikidata":"https://www.wikidata.org/wiki/Q1208096","display_name":"Diafiltration","level":4,"score":0.23829999566078186},{"id":"https://openalex.org/C135979968","wikidata":"https://www.wikidata.org/wiki/Q609809","display_name":"Protein isoform","level":5,"score":0.22139999270439148}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:arXiv.org:2407.14668","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2407.14668","pdf_url":"https://arxiv.org/pdf/2407.14668","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},{"id":"doi:10.48550/arxiv.2407.14668","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2407.14668","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2407.14668","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2407.14668","pdf_url":"https://arxiv.org/pdf/2407.14668","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},"sustainable_development_goals":[{"score":0.4535953998565674,"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Neuroscience":[0],"research":[1],"has":[2],"made":[3],"immense":[4],"progress":[5],"over":[6],"the":[7,14,20,32,81,111,125,158,181,185,191,198],"last":[8],"decade,":[9],"but":[10],"our":[11,101,152],"understanding":[12],"of":[13,22,41,63,121,160,184,197],"brain":[15,26,67,97,127,199],"remains":[16,39],"fragmented":[17],"and":[18,28,87,96,106,132,140,146,165],"piecemeal:":[19],"dream":[21],"probing":[23],"an":[24],"arbitrary":[25],"region":[27],"automatically":[29],"reading":[30],"out":[31,40,86],"information":[33],"encoded":[34],"in":[35,79],"its":[36],"neural":[37,54,89],"activity":[38,78,90,142],"reach.":[42],"In":[43],"this":[44],"work,":[45],"we":[46,103,178],"build":[47],"towards":[48],"a":[49,60,71,194],"first":[50],"foundation":[51,195],"model":[52,82,186,196],"for":[53,76,193],"spiking":[55],"data":[56],"that":[57,151,172],"can":[58,179],"solve":[59],"diverse":[61],"set":[62],"tasks":[64,109,137],"across":[65,91,129],"multiple":[66,176],"areas.":[68],"We":[69,149,169],"introduce":[70],"novel":[72],"self-supervised":[73],"modeling":[74],"approach":[75,155],"population":[77,163],"which":[80,118],"alternates":[83],"between":[84],"masking":[85],"reconstructing":[88],"different":[92],"time":[93],"steps,":[94],"neurons,":[95],"regions.":[98],"To":[99],"evaluate":[100],"approach,":[102],"design":[104],"unsupervised":[105],"supervised":[107],"prediction":[108,136],"using":[110],"International":[112],"Brain":[113],"Laboratory":[114],"repeated":[115],"site":[116],"dataset,":[117],"is":[119],"comprised":[120],"Neuropixels":[122],"recordings":[123],"targeting":[124],"same":[126],"locations":[128],"48":[130],"animals":[131],"experimental":[133],"sessions.":[134],"The":[135],"include":[138],"single-neuron":[139],"region-level":[141],"prediction,":[143,145],"forward":[144],"behavior":[147],"decoding.":[148],"demonstrate":[150],"multi-task-masking":[153],"(MtM)":[154],"significantly":[156],"improves":[157],"performance":[159],"current":[161],"state-of-the-art":[162],"models":[164],"enables":[166],"multi-task":[167],"learning.":[168],"also":[170],"show":[171],"by":[173],"training":[174],"on":[175],"animals,":[177,189],"improve":[180],"generalization":[182],"ability":[183],"to":[187],"unseen":[188],"paving":[190],"way":[192],"at":[200],"single-cell,":[201],"single-spike":[202],"resolution.":[203]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2025-11-06T06:51:31.235846","created_date":"2025-10-10T00:00:00"}