{"id":"https://openalex.org/W4390933356","doi":"https://doi.org/10.4108/eetel.4790","title":"A Review of Deep Learning Approaches for Early Diagnosis of Alzheimer's Disease","display_name":"A Review of Deep Learning Approaches for Early Diagnosis of Alzheimer's Disease","publication_year":2024,"publication_date":"2024-01-16","ids":{"openalex":"https://openalex.org/W4390933356","doi":"https://doi.org/10.4108/eetel.4790"},"language":"en","primary_location":{"id":"doi:10.4108/eetel.4790","is_oa":true,"landing_page_url":"http://dx.doi.org/10.4108/eetel.4790","pdf_url":"https://publications.eai.eu/index.php/el/article/download/4790/2830","source":{"id":"https://openalex.org/S2738947950","display_name":"ICST Transactions on e-Education and e-Learning","issn_l":"2032-9253","issn":["2032-9253"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310321144","host_organization_name":"Institute for Computer Sciences, Social Informatics and Telecommunications Engineering","host_organization_lineage":["https://openalex.org/P4310321144"],"host_organization_lineage_names":["Institute for Computer Sciences, Social Informatics and Telecommunications Engineering"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EAI Endorsed Transactions on e-Learning","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://publications.eai.eu/index.php/el/article/download/4790/2830","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054161156","display_name":"Mingxuan Xi","orcid":"https://orcid.org/0009-0001-8576-0249"},"institutions":[{"id":"https://openalex.org/I4210166499","display_name":"Henan Polytechnic University","ror":"https://ror.org/05vr1c885","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210166499"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"MengBo Xi","raw_affiliation_strings":["Henan Polytechnic University"],"affiliations":[{"raw_affiliation_string":"Henan Polytechnic University","institution_ids":["https://openalex.org/I4210166499"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054161156"],"corresponding_institution_ids":["https://openalex.org/I4210166499"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00439941,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9753999710083008,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9753999710083008,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9409999847412109,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/modalities","display_name":"Modalities","score":0.7018892765045166},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.6659447550773621},{"id":"https://openalex.org/keywords/dementia","display_name":"Dementia","score":0.6212021112442017},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5707406997680664},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.537056565284729},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.46348148584365845},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4581221342086792},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44977283477783203},{"id":"https://openalex.org/keywords/alzheimers-disease","display_name":"Alzheimer's disease","score":0.43856915831565857},{"id":"https://openalex.org/keywords/therapeutic-modalities","display_name":"Therapeutic modalities","score":0.42778560519218445},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.20347881317138672},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.07438182830810547}],"concepts":[{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.7018892765045166},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6659447550773621},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.6212021112442017},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5707406997680664},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.537056565284729},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.46348148584365845},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4581221342086792},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44977283477783203},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.43856915831565857},{"id":"https://openalex.org/C3019692148","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Therapeutic modalities","level":2,"score":0.42778560519218445},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20347881317138672},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07438182830810547},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4108/eetel.4790","is_oa":true,"landing_page_url":"http://dx.doi.org/10.4108/eetel.4790","pdf_url":"https://publications.eai.eu/index.php/el/article/download/4790/2830","source":{"id":"https://openalex.org/S2738947950","display_name":"ICST Transactions on e-Education and e-Learning","issn_l":"2032-9253","issn":["2032-9253"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310321144","host_organization_name":"Institute for Computer Sciences, Social Informatics and Telecommunications Engineering","host_organization_lineage":["https://openalex.org/P4310321144"],"host_organization_lineage_names":["Institute for Computer Sciences, Social Informatics and Telecommunications Engineering"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EAI Endorsed Transactions on e-Learning","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.4108/eetel.4790","is_oa":true,"landing_page_url":"http://dx.doi.org/10.4108/eetel.4790","pdf_url":"https://publications.eai.eu/index.php/el/article/download/4790/2830","source":{"id":"https://openalex.org/S2738947950","display_name":"ICST Transactions on e-Education and e-Learning","issn_l":"2032-9253","issn":["2032-9253"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310321144","host_organization_name":"Institute for Computer Sciences, Social Informatics and Telecommunications Engineering","host_organization_lineage":["https://openalex.org/P4310321144"],"host_organization_lineage_names":["Institute for Computer Sciences, Social Informatics and Telecommunications Engineering"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EAI Endorsed Transactions on e-Learning","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4699999988079071}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4390933356.pdf"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W596427627","https://openalex.org/W1557641067","https://openalex.org/W2123957845","https://openalex.org/W2135028448","https://openalex.org/W2150825673","https://openalex.org/W2194999895","https://openalex.org/W2209545160","https://openalex.org/W2277307048","https://openalex.org/W2426986800","https://openalex.org/W2770131355","https://openalex.org/W2782815868","https://openalex.org/W2788663687","https://openalex.org/W2794356790","https://openalex.org/W2806489700","https://openalex.org/W2900542708","https://openalex.org/W2905224888","https://openalex.org/W2907148404","https://openalex.org/W2909420490","https://openalex.org/W2916257687","https://openalex.org/W2921824753","https://openalex.org/W2930696305","https://openalex.org/W2944541202","https://openalex.org/W2945065837","https://openalex.org/W2952992882","https://openalex.org/W2954528538","https://openalex.org/W2990007740","https://openalex.org/W2997873617","https://openalex.org/W3000648255","https://openalex.org/W3004621388","https://openalex.org/W3007274952","https://openalex.org/W3014140399","https://openalex.org/W3017328779","https://openalex.org/W3028024203","https://openalex.org/W3034005492","https://openalex.org/W3036726364","https://openalex.org/W3046002895","https://openalex.org/W3083429304","https://openalex.org/W3095441110","https://openalex.org/W3095591236","https://openalex.org/W3104971239","https://openalex.org/W3110796009","https://openalex.org/W3115069763","https://openalex.org/W3121966255","https://openalex.org/W3126090805","https://openalex.org/W3127420280","https://openalex.org/W3152893301","https://openalex.org/W3158631207","https://openalex.org/W3168997536","https://openalex.org/W3172787012","https://openalex.org/W3197215693","https://openalex.org/W3206202156","https://openalex.org/W3208450319","https://openalex.org/W3211550414","https://openalex.org/W3212514517","https://openalex.org/W4205251401","https://openalex.org/W4224246814","https://openalex.org/W4295095912","https://openalex.org/W4299833503","https://openalex.org/W4377234261","https://openalex.org/W4385621509","https://openalex.org/W6633439375"],"related_works":["https://openalex.org/W1994512397","https://openalex.org/W2740809346","https://openalex.org/W4249806725","https://openalex.org/W4388242840","https://openalex.org/W649759291","https://openalex.org/W1533411842","https://openalex.org/W2043363698","https://openalex.org/W588278408","https://openalex.org/W4391079597","https://openalex.org/W2492163052"],"abstract_inverted_index":{"Alzheimer's":[0,68],"disease":[1,69],"(AD),":[2],"one":[3],"of":[4,15,25,38,45,50,118,124,129,136,142],"the":[5,11,36,39,42,48,85,92,99,112,119,122,133],"major":[6],"neurodegenerative":[7],"diseases,":[8],"has":[9,73],"become":[10,74],"most":[12],"common":[13],"cause":[14],"dementia":[16],"problems.":[17],"Up":[18],"to":[19,34],"now,":[20],"there":[21],"is":[22],"a":[23,75,127],"lack":[24],"effective":[26,31],"targeted":[27],"therapeutic":[28],"drugs":[29],"and":[30,121,138,147],"treatment":[32],"modalities":[33,131],"stop":[35],"progression":[37],"disease.":[40],"With":[41],"continuous":[43],"development":[44],"computer":[46],"technology,":[47],"use":[49,123],"computer-aided":[51],"diagnostic":[52],"technology":[53],"tools":[54],"for":[55,106,132],"AD":[56,93,107,143],"early":[57,134],"classification":[58,72,95,104,135,144],"studies":[59,113],"will":[60],"provide":[61],"clinicians":[62],"with":[63],"important":[64],"assistance.":[65],"Deep":[66],"learning-based":[67],"(AD)":[70],"imaging":[71,94],"current":[76],"research":[77,149],"hotspot.":[78],"In":[79],"this":[80],"paper,":[81],"we":[82,110],"first":[83],"describe":[84],"commonly":[86,100],"used":[87,101],"publicly":[88],"available":[89],"datasets":[90],"in":[91],"task;":[96],"then":[97],"introduce":[98],"deep":[102],"learning":[103],"models":[105],"diagnosis;":[108],"secondly,":[109],"compare":[111],"that":[114],"target":[115],"different":[116,130],"biomarkers":[117],"subjects":[120],"unimodal":[125],"or":[126],"combination":[128],"AD;":[137],"finally,":[139],"The":[140],"challenges":[141],"are":[145,151],"summarized":[146],"future":[148],"directions":[150],"proposed.":[152]},"counts_by_year":[],"updated_date":"2026-02-03T00:53:05.648605","created_date":"2025-10-10T00:00:00"}
