{"id":"https://openalex.org/W4407550526","doi":"https://doi.org/10.3390/sym17020285","title":"Time-Irreversible Quantum-Classical Dynamics of Molecular Models in the Brain","display_name":"Time-Irreversible Quantum-Classical Dynamics of Molecular Models in the Brain","publication_year":2025,"publication_date":"2025-02-13","ids":{"openalex":"https://openalex.org/W4407550526","doi":"https://doi.org/10.3390/sym17020285"},"language":"en","primary_location":{"id":"doi:10.3390/sym17020285","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym17020285","pdf_url":"https://www.mdpi.com/2073-8994/17/2/285/pdf?version=1739436818","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2073-8994/17/2/285/pdf?version=1739436818","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035776559","display_name":"Alessandro Sergi","orcid":"https://orcid.org/0000-0003-3954-0445"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]},{"id":"https://openalex.org/I177181097","display_name":"Durban University of Technology","ror":"https://ror.org/0303y7a51","country_code":"ZA","type":"education","lineage":["https://openalex.org/I177181097"]}],"countries":["IT","ZA"],"is_corresponding":true,"raw_author_name":"Alessandro Sergi","raw_affiliation_strings":["Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Universit\u00e0 degli Studi di Messina, Viale F. Stagno d\u2019Alcontres 31, 98166 Messina, Italy","Institute of Systems Science, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa"],"raw_orcid":"https://orcid.org/0000-0003-3954-0445","affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Universit\u00e0 degli Studi di Messina, Viale F. Stagno d\u2019Alcontres 31, 98166 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Institute of Systems Science, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa","institution_ids":["https://openalex.org/I177181097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065761605","display_name":"A. Messina","orcid":"https://orcid.org/0000-0002-3367-0129"},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonino Messina","raw_affiliation_strings":["Dipartimento di Matematica ed Informatica, Universit\u00e0 di Palermo, Via Archirafi 34, 90123 Palermo, Italy"],"raw_orcid":"https://orcid.org/0000-0002-3367-0129","affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica ed Informatica, Universit\u00e0 di Palermo, Via Archirafi 34, 90123 Palermo, Italy","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053524200","display_name":"Rosalba Saija","orcid":"https://orcid.org/0000-0002-5823-9749"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosalba Saija","raw_affiliation_strings":["Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Universit\u00e0 degli Studi di Messina, Viale F. Stagno d\u2019Alcontres 31, 98166 Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0002-5823-9749","affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Universit\u00e0 degli Studi di Messina, Viale F. Stagno d\u2019Alcontres 31, 98166 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061720984","display_name":"Gabriella Martino","orcid":"https://orcid.org/0000-0001-9488-2021"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gabriella Martino","raw_affiliation_strings":["Dipartimento di Medicina e Clinica Sperimentale, Universit\u00e0 degli Studi di Messina, Via Consolare Valeria, 98125 Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9488-2021","affiliations":[{"raw_affiliation_string":"Dipartimento di Medicina e Clinica Sperimentale, Universit\u00e0 degli Studi di Messina, Via Consolare Valeria, 98125 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017710513","display_name":"Maria Teresa Caccamo","orcid":"https://orcid.org/0000-0003-2417-0998"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Teresa Caccamo","raw_affiliation_strings":["Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Universit\u00e0 degli Studi di Messina, Viale F. Stagno d\u2019Alcontres 31, 98166 Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0003-2417-0998","affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Universit\u00e0 degli Studi di Messina, Viale F. Stagno d\u2019Alcontres 31, 98166 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081920807","display_name":"Min\u2010Fang Kuo","orcid":"https://orcid.org/0000-0001-9955-0237"},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]},{"id":"https://openalex.org/I4210166399","display_name":"Leibniz Research Centre for Working Environment and Human Factors","ror":"https://ror.org/05cj29x94","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210166399"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Min-Fang Kuo","raw_affiliation_strings":["Department Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany","institution_ids":["https://openalex.org/I200332995","https://openalex.org/I4210166399"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052849808","display_name":"Michael A. Nitsche","orcid":"https://orcid.org/0000-0002-2207-5965"},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]},{"id":"https://openalex.org/I20121455","display_name":"Bielefeld University","ror":"https://ror.org/02hpadn98","country_code":"DE","type":"education","lineage":["https://openalex.org/I20121455"]},{"id":"https://openalex.org/I4210166399","display_name":"Leibniz Research Centre for Working Environment and Human Factors","ror":"https://ror.org/05cj29x94","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210166399"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael A. Nitsche","raw_affiliation_strings":["Department Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany","German Center for Mental Health (DZPG), 44787 Bochum, Germany","University Clinic of Psychiatry and Psychotherapy, Protestant Hospital of Bethel Foundation, University Hospital OWL, Bielefeld University, 33602 Bielefeld, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany","institution_ids":["https://openalex.org/I200332995","https://openalex.org/I4210166399"]},{"raw_affiliation_string":"German Center for Mental Health (DZPG), 44787 Bochum, Germany","institution_ids":[]},{"raw_affiliation_string":"University Clinic of Psychiatry and Psychotherapy, Protestant Hospital of Bethel Foundation, University Hospital OWL, Bielefeld University, 33602 Bielefeld, Germany","institution_ids":["https://openalex.org/I20121455"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5035776559"],"corresponding_institution_ids":["https://openalex.org/I112862951","https://openalex.org/I177181097"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2227},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2227},"fwci":2.2534,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.86860173,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"17","issue":"2","first_page":"285","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.5679810643196106},{"id":"https://openalex.org/keywords/quantum","display_name":"Quantum","score":0.5587570667266846},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.4397067129611969},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4111732244491577},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3659827709197998},{"id":"https://openalex.org/keywords/quantum-mechanics","display_name":"Quantum mechanics","score":0.19160151481628418}],"concepts":[{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.5679810643196106},{"id":"https://openalex.org/C84114770","wikidata":"https://www.wikidata.org/wiki/Q46344","display_name":"Quantum","level":2,"score":0.5587570667266846},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.4397067129611969},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4111732244491577},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3659827709197998},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.19160151481628418},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3390/sym17020285","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym17020285","pdf_url":"https://www.mdpi.com/2073-8994/17/2/285/pdf?version=1739436818","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},{"id":"pmh:oai:arXiv.org:2503.00016","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2503.00016","pdf_url":"https://arxiv.org/pdf/2503.00016","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"doi:10.3390/sym17020285","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym17020285","pdf_url":"https://www.mdpi.com/2073-8994/17/2/285/pdf?version=1739436818","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4407550526.pdf","grobid_xml":"https://content.openalex.org/works/W4407550526.grobid-xml"},"referenced_works_count":117,"referenced_works":["https://openalex.org/W154899493","https://openalex.org/W564178665","https://openalex.org/W1013236036","https://openalex.org/W1520965145","https://openalex.org/W1555048232","https://openalex.org/W1577794226","https://openalex.org/W1765870892","https://openalex.org/W1784323277","https://openalex.org/W1945342219","https://openalex.org/W1965850850","https://openalex.org/W1967118651","https://openalex.org/W1972833860","https://openalex.org/W1972979585","https://openalex.org/W1974849576","https://openalex.org/W1977661538","https://openalex.org/W1980373602","https://openalex.org/W1981983416","https://openalex.org/W1982584763","https://openalex.org/W1985940938","https://openalex.org/W1993488859","https://openalex.org/W2002558972","https://openalex.org/W2005935750","https://openalex.org/W2007948277","https://openalex.org/W2007997142","https://openalex.org/W2014354687","https://openalex.org/W2022291592","https://openalex.org/W2026462610","https://openalex.org/W2028018919","https://openalex.org/W2028180232","https://openalex.org/W2034790516","https://openalex.org/W2037564010","https://openalex.org/W2042941423","https://openalex.org/W2045285234","https://openalex.org/W2046971981","https://openalex.org/W2062950378","https://openalex.org/W2065434728","https://openalex.org/W2072710969","https://openalex.org/W2079948225","https://openalex.org/W2083318404","https://openalex.org/W2085319761","https://openalex.org/W2085550443","https://openalex.org/W2086634221","https://openalex.org/W2086842761","https://openalex.org/W2096352657","https://openalex.org/W2097273459","https://openalex.org/W2113470584","https://openalex.org/W2114329358","https://openalex.org/W2125303188","https://openalex.org/W2130559640","https://openalex.org/W2133081188","https://openalex.org/W2133301037","https://openalex.org/W2135027517","https://openalex.org/W2137551402","https://openalex.org/W2151629389","https://openalex.org/W2157508442","https://openalex.org/W2162932719","https://openalex.org/W2164333417","https://openalex.org/W2166037666","https://openalex.org/W2168516666","https://openalex.org/W2172168442","https://openalex.org/W2180999472","https://openalex.org/W2241029506","https://openalex.org/W2475557713","https://openalex.org/W2503557239","https://openalex.org/W2534420584","https://openalex.org/W2566892547","https://openalex.org/W2582012066","https://openalex.org/W2612624656","https://openalex.org/W2725903383","https://openalex.org/W2754376969","https://openalex.org/W2769090736","https://openalex.org/W2806967619","https://openalex.org/W2821011129","https://openalex.org/W2889338430","https://openalex.org/W2897283869","https://openalex.org/W2900404755","https://openalex.org/W2947255760","https://openalex.org/W2949154473","https://openalex.org/W2963970956","https://openalex.org/W3001094081","https://openalex.org/W3002992256","https://openalex.org/W3005672667","https://openalex.org/W3007144788","https://openalex.org/W3014097088","https://openalex.org/W3046536917","https://openalex.org/W3101603427","https://openalex.org/W3105439835","https://openalex.org/W3105763570","https://openalex.org/W3118458469","https://openalex.org/W3122365169","https://openalex.org/W3122831421","https://openalex.org/W3130843357","https://openalex.org/W3134477421","https://openalex.org/W3144938829","https://openalex.org/W4200004785","https://openalex.org/W4210955860","https://openalex.org/W4229706587","https://openalex.org/W4235843414","https://openalex.org/W4236575607","https://openalex.org/W4244013995","https://openalex.org/W4285092699","https://openalex.org/W4294544773","https://openalex.org/W4297238654","https://openalex.org/W4317107525","https://openalex.org/W4323305090","https://openalex.org/W4362581995","https://openalex.org/W4377289507","https://openalex.org/W4378349023","https://openalex.org/W4388167314","https://openalex.org/W4389432396","https://openalex.org/W4394950159","https://openalex.org/W4400379356","https://openalex.org/W4401249592","https://openalex.org/W6628509688","https://openalex.org/W6773843273","https://openalex.org/W6790716906","https://openalex.org/W6818682872"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2935759653","https://openalex.org/W3105167352","https://openalex.org/W54078636","https://openalex.org/W2954470139","https://openalex.org/W1501425562","https://openalex.org/W2902782467","https://openalex.org/W3084825885"],"abstract_inverted_index":{"This":[0],"manuscript":[1],"aims":[2],"to":[3,10,13,41,65,87,109,117,136,150],"illustrate":[4],"a":[5,128],"quantum-classical":[6],"dissipative":[7,76,89],"theory":[8,73],"(suited":[9],"be":[11,75,88],"converted":[12],"effective":[14,115],"algorithms":[15],"for":[16,123],"numerical":[17],"simulations)":[18],"within":[19],"the":[20,28,35,39,52,60,68,91,106,132],"long-term":[21],"project":[22],"of":[23,79,121,140,164],"studying":[24,51],"molecular":[25],"processes":[26,85],"in":[27,34,127],"brain.":[29,53],"Other":[30],"approaches,":[31],"briefly":[32],"sketched":[33],"text,":[36],"have":[37],"advocated":[38],"need":[40],"deal":[42],"with":[43,56],"both":[44],"quantum":[45,125,151],"and":[46,94,142,157,161,166,171],"classical":[47,69,129,138],"dynamic":[48],"variables":[49,153],"when":[50],"At":[54],"variance":[55],"these":[57],"other":[58],"frameworks,":[59],"manuscript\u2019s":[61],"formalism":[62],"allows":[63],"us":[64],"explicitly":[66],"treat":[67],"dynamical":[70,152],"variables.":[71],"The":[72],"must":[74],"not":[77],"because":[78,83],"formal":[80],"requirements":[81],"but":[82],"brain":[84],"appear":[86],"at":[90],"molecular,":[92],"physiological,":[93],"high":[95],"functional":[96],"levels.":[97],"We":[98,134],"discuss":[99],"theoretically":[100],"that":[101],"using":[102],"Brownian":[103],"dynamics":[104],"or":[105],"Nos\u00e8-Hoover-Chain":[107],"thermostat":[108],"perform":[110],"computer":[111],"simulations":[112],"provides":[113],"an":[114,119],"way":[116],"introduce":[118],"arrow":[120],"time":[122],"open":[124],"systems":[126],"environment.":[130],"In":[131],"future,":[133],"plan":[135],"study":[137],"models":[139],"neurons":[141],"astrocytes,":[143],"as":[144,146],"well":[145],"their":[147],"networks,":[148],"coupled":[149],"describing,":[154],"e.g.,":[155],"nuclear":[156],"electron":[158],"spins,":[159],"HOMO":[160],"LUMO":[162],"orbitals":[163],"phenyl":[165],"indole":[167],"rings,":[168],"ion":[169],"channels,":[170],"tunneling":[172],"protons.":[173]},"counts_by_year":[{"year":2025,"cited_by_count":5}],"updated_date":"2026-08-18T07:49:30.821534","created_date":"2025-10-10T00:00:00"}