{"id":"https://openalex.org/W3154707942","doi":"https://doi.org/10.3390/sym13040695","title":"Atypical Brain Asymmetry in Human Situs Inversus: Gut Feeling or Real Evidence?","display_name":"Atypical Brain Asymmetry in Human Situs Inversus: Gut Feeling or Real Evidence?","publication_year":2021,"publication_date":"2021-04-16","ids":{"openalex":"https://openalex.org/W3154707942","doi":"https://doi.org/10.3390/sym13040695","mag":"3154707942"},"language":"en","primary_location":{"id":"doi:10.3390/sym13040695","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym13040695","pdf_url":"https://www.mdpi.com/2073-8994/13/4/695/pdf?version=1618547553","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2073-8994/13/4/695/pdf?version=1618547553","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040885938","display_name":"Guy Vingerhoets","orcid":"https://orcid.org/0000-0001-6726-3858"},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Guy Vingerhoets","raw_affiliation_strings":["Department of Experimental Psychology, Ghent University, 9000 Ghent, Belgium"],"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology, Ghent University, 9000 Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018473758","display_name":"Robin Gerrits","orcid":"https://orcid.org/0000-0001-7148-9657"},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Robin Gerrits","raw_affiliation_strings":["Department of Experimental Psychology, Ghent University, 9000 Ghent, Belgium"],"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology, Ghent University, 9000 Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033573389","display_name":"Helena Verhelst","orcid":"https://orcid.org/0000-0002-6861-0249"},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Helena Verhelst","raw_affiliation_strings":["Department of Experimental Psychology, Ghent University, 9000 Ghent, Belgium"],"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology, Ghent University, 9000 Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5040885938"],"corresponding_institution_ids":["https://openalex.org/I2801227569"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2165},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2165},"fwci":1.3013,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.77730948,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"13","issue":"4","first_page":"695","last_page":"695"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12621","display_name":"Hemispheric Asymmetry in Neuroscience","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12621","display_name":"Hemispheric Asymmetry in Neuroscience","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12417","display_name":"Morphological variations and asymmetry","score":0.9136000275611877,"subfield":{"id":"https://openalex.org/subfields/2608","display_name":"Geometry and Topology"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/situs-inversus","display_name":"Situs inversus","score":0.9411646723747253},{"id":"https://openalex.org/keywords/laterality","display_name":"Laterality","score":0.7481307983398438},{"id":"https://openalex.org/keywords/human-brain","display_name":"Human brain","score":0.49325889348983765},{"id":"https://openalex.org/keywords/brain-asymmetry","display_name":"Brain asymmetry","score":0.4602358341217041},{"id":"https://openalex.org/keywords/heterotaxy","display_name":"Heterotaxy","score":0.4510207176208496},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.4425141513347626},{"id":"https://openalex.org/keywords/cilium","display_name":"Cilium","score":0.41223087906837463},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.35400092601776123},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.337592214345932},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3375489115715027},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3089487850666046},{"id":"https://openalex.org/keywords/lateralization-of-brain-function","display_name":"Lateralization of brain function","score":0.2813445031642914},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.184327632188797},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.10773923993110657}],"concepts":[{"id":"https://openalex.org/C2779104077","wikidata":"https://www.wikidata.org/wiki/Q1456383","display_name":"Situs inversus","level":2,"score":0.9411646723747253},{"id":"https://openalex.org/C171508891","wikidata":"https://www.wikidata.org/wiki/Q10927834","display_name":"Laterality","level":2,"score":0.7481307983398438},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.49325889348983765},{"id":"https://openalex.org/C195650424","wikidata":"https://www.wikidata.org/wiki/Q4955813","display_name":"Brain asymmetry","level":3,"score":0.4602358341217041},{"id":"https://openalex.org/C2910136558","wikidata":"https://www.wikidata.org/wiki/Q83851589","display_name":"Heterotaxy","level":3,"score":0.4510207176208496},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4425141513347626},{"id":"https://openalex.org/C100094513","wikidata":"https://www.wikidata.org/wiki/Q180436","display_name":"Cilium","level":2,"score":0.41223087906837463},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35400092601776123},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.337592214345932},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3375489115715027},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3089487850666046},{"id":"https://openalex.org/C79840881","wikidata":"https://www.wikidata.org/wiki/Q1080497","display_name":"Lateralization of brain function","level":2,"score":0.2813445031642914},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.184327632188797},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10773923993110657},{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/sym13040695","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym13040695","pdf_url":"https://www.mdpi.com/2073-8994/13/4/695/pdf?version=1618547553","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},{"id":"pmh:oai:lirias2repo.kuleuven.be:20.500.12942/771864","is_oa":true,"landing_page_url":"https://lirias.kuleuven.be/handle/20.500.12942/771864","pdf_url":null,"source":{"id":"https://openalex.org/S4306401954","display_name":"Lirias (KU Leuven)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I99464096","host_organization_name":"KU Leuven","host_organization_lineage":["https://openalex.org/I99464096"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Symmetry-Basel, vol. 13 (4), Art.No. ARTN 695","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:archive.ugent.be:8739806","is_oa":true,"landing_page_url":"https://biblio.ugent.be/publication/8739806","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 2073-8994","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:9b2d5d333cdf464d9d372d404f119e84","is_oa":true,"landing_page_url":"https://doaj.org/article/9b2d5d333cdf464d9d372d404f119e84","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Symmetry, Vol 13, Iss 4, p 695 (2021)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/2073-8994/13/4/695/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/sym13040695","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pages: 695","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/sym13040695","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym13040695","pdf_url":"https://www.mdpi.com/2073-8994/13/4/695/pdf?version=1618547553","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4049244138","display_name":null,"funder_award_id":"G.0111416N","funder_id":"https://openalex.org/F4320321730","funder_display_name":"Fonds Wetenschappelijk Onderzoek"}],"funders":[{"id":"https://openalex.org/F4320321730","display_name":"Fonds Wetenschappelijk Onderzoek","ror":"https://ror.org/03qtxy027"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3154707942.pdf","grobid_xml":"https://content.openalex.org/works/W3154707942.grobid-xml"},"referenced_works_count":109,"referenced_works":["https://openalex.org/W152649905","https://openalex.org/W161301760","https://openalex.org/W1533660381","https://openalex.org/W1566185201","https://openalex.org/W1891543180","https://openalex.org/W1969169776","https://openalex.org/W1974651731","https://openalex.org/W1977838795","https://openalex.org/W1980992128","https://openalex.org/W1980994010","https://openalex.org/W1982168739","https://openalex.org/W1983538981","https://openalex.org/W1993379867","https://openalex.org/W1995213027","https://openalex.org/W2000271788","https://openalex.org/W2003734939","https://openalex.org/W2005796695","https://openalex.org/W2014753994","https://openalex.org/W2016504972","https://openalex.org/W2017497088","https://openalex.org/W2018925150","https://openalex.org/W2023059002","https://openalex.org/W2024686766","https://openalex.org/W2027211393","https://openalex.org/W2029279705","https://openalex.org/W2031974533","https://openalex.org/W2032926383","https://openalex.org/W2033941024","https://openalex.org/W2035036804","https://openalex.org/W2037335896","https://openalex.org/W2041119049","https://openalex.org/W2043808435","https://openalex.org/W2048374378","https://openalex.org/W2048829557","https://openalex.org/W2049734059","https://openalex.org/W2049976613","https://openalex.org/W2051762601","https://openalex.org/W2060036615","https://openalex.org/W2060735786","https://openalex.org/W2064659330","https://openalex.org/W2066661906","https://openalex.org/W2067658938","https://openalex.org/W2070863448","https://openalex.org/W2073264990","https://openalex.org/W2074674911","https://openalex.org/W2075082427","https://openalex.org/W2076057900","https://openalex.org/W2079319450","https://openalex.org/W2079466347","https://openalex.org/W2083279645","https://openalex.org/W2088352274","https://openalex.org/W2094996734","https://openalex.org/W2094999461","https://openalex.org/W2096731847","https://openalex.org/W2105375033","https://openalex.org/W2106586740","https://openalex.org/W2112148316","https://openalex.org/W2112705190","https://openalex.org/W2114979424","https://openalex.org/W2118353656","https://openalex.org/W2123753605","https://openalex.org/W2124397780","https://openalex.org/W2127131319","https://openalex.org/W2134041631","https://openalex.org/W2136718483","https://openalex.org/W2140808203","https://openalex.org/W2142498157","https://openalex.org/W2143818436","https://openalex.org/W2145827570","https://openalex.org/W2153039094","https://openalex.org/W2154651740","https://openalex.org/W2155138073","https://openalex.org/W2156098321","https://openalex.org/W2160564717","https://openalex.org/W2163035368","https://openalex.org/W2164483683","https://openalex.org/W2164517652","https://openalex.org/W2167773905","https://openalex.org/W2172099999","https://openalex.org/W2174865715","https://openalex.org/W2282703556","https://openalex.org/W2313023886","https://openalex.org/W2585224979","https://openalex.org/W2593482707","https://openalex.org/W2729579672","https://openalex.org/W2736170909","https://openalex.org/W2750639649","https://openalex.org/W2781624984","https://openalex.org/W2790486857","https://openalex.org/W2804014605","https://openalex.org/W2885800130","https://openalex.org/W2910059578","https://openalex.org/W2925277577","https://openalex.org/W2948551117","https://openalex.org/W2952911685","https://openalex.org/W2953288566","https://openalex.org/W2979321298","https://openalex.org/W3003327349","https://openalex.org/W3004122433","https://openalex.org/W3010586273","https://openalex.org/W3012981809","https://openalex.org/W3014403984","https://openalex.org/W3033670601","https://openalex.org/W3136572316","https://openalex.org/W4294215472","https://openalex.org/W4388331938","https://openalex.org/W6631890708","https://openalex.org/W6695189133","https://openalex.org/W6747550445"],"related_works":["https://openalex.org/W2083193387","https://openalex.org/W2060825467","https://openalex.org/W1525737988","https://openalex.org/W2157486440","https://openalex.org/W3021988853","https://openalex.org/W3133660542","https://openalex.org/W2511473940","https://openalex.org/W3164531195","https://openalex.org/W2313023886","https://openalex.org/W2091185446"],"abstract_inverted_index":{"The":[0,102],"alignment":[1],"of":[2,15,59,62,80,136,163,172],"visceral":[3,25,37,64,87,98,110],"and":[4,26,55,65,83,111,128,158,177],"brain":[5,27,47,66,84,112,129,165],"asymmetry":[6,32,85,162],"observed":[7],"in":[8,21,86],"some":[9],"vertebrate":[10,63],"species":[11],"raises":[12],"the":[13,24,51,56,72,78,96,122,143,159,164],"question":[14],"whether":[16],"this":[17],"association":[18],"also":[19],"exists":[20],"humans.":[22],"While":[23],"systems":[28],"may":[29,139],"have":[30,42],"developed":[31],"for":[33,126,151],"different":[34],"reasons,":[35],"basic":[36],"left\u2013right":[38,60],"differentiation":[39,61],"mechanisms":[40],"could":[41],"been":[43],"duplicated":[44],"to":[45],"establish":[46],"asymmetry.":[48],"We":[49],"describe":[50],"main":[52],"phenotypical":[53],"anomalies":[54],"general":[57],"mechanism":[58],"laterality.":[67],"Next,":[68],"we":[69],"systematically":[70],"review":[71],"available":[73],"human":[74,109],"studies":[75,148],"that":[76],"explored":[77],"prevalence":[79,135],"atypical":[81],"behavioral":[82],"situs":[88,119,156,173],"anomalies,":[89],"which":[90],"almost":[91],"exclusively":[92],"involved":[93],"participants":[94,117],"with":[95,118,167,175],"mirrored":[97],"organization":[99],"(situs":[100],"inversus).":[101],"data":[103],"show":[104,121],"no":[105],"direct":[106],"link":[107],"between":[108,155,170],"functional":[113,130,137],"laterality":[114],"as":[115],"most":[116],"inversus":[120,157,174],"typical":[123],"population":[124],"bias":[125],"handedness":[127],"asymmetry,":[131],"although":[132],"an":[133],"increased":[134],"crowding":[138],"be":[140],"present.":[141],"At":[142],"same":[144],"time,":[145],"several":[146],"independent":[147],"present":[149],"evidence":[150],"a":[152],"possible":[153],"relation":[154],"gross":[160],"morphological":[161],"torque":[166],"potential":[168],"differences":[169],"subtypes":[171],"ciliary":[176],"non-ciliary":[178],"etiologies.":[179]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2025-10-10T00:00:00"}
