{"id":"https://openalex.org/W2977700666","doi":"https://doi.org/10.3390/sym11101215","title":"Symmetry and Dissymmetry in Protein Structure\u2014System-Coding Its Biological Specificity","display_name":"Symmetry and Dissymmetry in Protein Structure\u2014System-Coding Its Biological Specificity","publication_year":2019,"publication_date":"2019-09-30","ids":{"openalex":"https://openalex.org/W2977700666","doi":"https://doi.org/10.3390/sym11101215","mag":"2977700666"},"language":"en","primary_location":{"id":"doi:10.3390/sym11101215","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym11101215","pdf_url":"https://www.mdpi.com/2073-8994/11/10/1215/pdf?version=1569824667","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2073-8994/11/10/1215/pdf?version=1569824667","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068559370","display_name":"Mateusz Banach","orcid":"https://orcid.org/0000-0003-1806-9877"},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Mateusz Banach","raw_affiliation_strings":["Department of Bioinformatics and Telemedicine, Medical College, Jagiellonian University, \u0141azarza 16, 31-530 Krakow, Poland"],"raw_orcid":"https://orcid.org/0000-0003-1806-9877","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics and Telemedicine, Medical College, Jagiellonian University, \u0141azarza 16, 31-530 Krakow, Poland","institution_ids":["https://openalex.org/I126596746"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027144155","display_name":"Leszek Konieczny","orcid":null},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Leszek Konieczny","raw_affiliation_strings":["Medical Biochemistry, Medical College, Jagiellonian University, Kopernika 7, 31-034 Krak\u00f3w, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Biochemistry, Medical College, Jagiellonian University, Kopernika 7, 31-034 Krak\u00f3w, Poland","institution_ids":["https://openalex.org/I126596746"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087239926","display_name":"Irena Roterman","orcid":"https://orcid.org/0000-0003-3652-9099"},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Irena Roterman","raw_affiliation_strings":["Department of Bioinformatics and Telemedicine, Medical College, Jagiellonian University, \u0141azarza 16, 31-530 Krakow, Poland"],"raw_orcid":"https://orcid.org/0000-0003-3652-9099","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics and Telemedicine, Medical College, Jagiellonian University, \u0141azarza 16, 31-530 Krakow, Poland","institution_ids":["https://openalex.org/I126596746"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5087239926"],"corresponding_institution_ids":["https://openalex.org/I126596746"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2165},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2165},"fwci":0.0855,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.48203761,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"11","issue":"10","first_page":"1215","last_page":"1215"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/symmetry","display_name":"Symmetry (geometry)","score":0.6092265248298645},{"id":"https://openalex.org/keywords/homogeneous-space","display_name":"Homogeneous space","score":0.5635116696357727},{"id":"https://openalex.org/keywords/chemical-physics","display_name":"Chemical physics","score":0.5308576226234436},{"id":"https://openalex.org/keywords/gaussian","display_name":"Gaussian","score":0.491359144449234},{"id":"https://openalex.org/keywords/translational-symmetry","display_name":"Translational symmetry","score":0.4690832197666168},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.45482566952705383},{"id":"https://openalex.org/keywords/translation","display_name":"Translation (biology)","score":0.4408777952194214},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.41973063349723816},{"id":"https://openalex.org/keywords/crystallography","display_name":"Crystallography","score":0.41940271854400635},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.40375763177871704},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3234546184539795},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.23808971047401428},{"id":"https://openalex.org/keywords/computational-chemistry","display_name":"Computational chemistry","score":0.21688103675842285},{"id":"https://openalex.org/keywords/condensed-matter-physics","display_name":"Condensed matter physics","score":0.16557008028030396},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.15248903632164001},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13005897402763367},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.08805322647094727}],"concepts":[{"id":"https://openalex.org/C2779886137","wikidata":"https://www.wikidata.org/wiki/Q21030012","display_name":"Symmetry (geometry)","level":2,"score":0.6092265248298645},{"id":"https://openalex.org/C96469262","wikidata":"https://www.wikidata.org/wiki/Q1324364","display_name":"Homogeneous space","level":2,"score":0.5635116696357727},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.5308576226234436},{"id":"https://openalex.org/C163716315","wikidata":"https://www.wikidata.org/wiki/Q901177","display_name":"Gaussian","level":2,"score":0.491359144449234},{"id":"https://openalex.org/C84229","wikidata":"https://www.wikidata.org/wiki/Q2116709","display_name":"Translational symmetry","level":2,"score":0.4690832197666168},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45482566952705383},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.4408777952194214},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.41973063349723816},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.41940271854400635},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.40375763177871704},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3234546184539795},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.23808971047401428},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.21688103675842285},{"id":"https://openalex.org/C26873012","wikidata":"https://www.wikidata.org/wiki/Q214781","display_name":"Condensed matter physics","level":1,"score":0.16557008028030396},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.15248903632164001},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13005897402763367},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08805322647094727},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/sym11101215","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym11101215","pdf_url":"https://www.mdpi.com/2073-8994/11/10/1215/pdf?version=1569824667","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},{"id":"pmh:oai:ruj.uj.edu.pl:item/256545","is_oa":true,"landing_page_url":"https://ruj.uj.edu.pl/xmlui/handle/item/256545","pdf_url":null,"source":{"id":"https://openalex.org/S4306401249","display_name":"Jagiellonian University Repository (Jagiellonian University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I126596746","host_organization_name":"Jagiellonian University","host_organization_lineage":["https://openalex.org/I126596746"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:39b0930677714b638e6acbad5d246d96","is_oa":true,"landing_page_url":"https://doaj.org/article/39b0930677714b638e6acbad5d246d96","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Symmetry, Vol 11, Iss 10, p 1215 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/sym11101215","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym11101215","pdf_url":"https://www.mdpi.com/2073-8994/11/10/1215/pdf?version=1569824667","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5624552035","display_name":null,"funder_award_id":"N41/DBS/000211","funder_id":"https://openalex.org/F4320310970","funder_display_name":"Uniwersytet Jagiello\u0144ski Collegium Medicum"}],"funders":[{"id":"https://openalex.org/F4320310970","display_name":"Uniwersytet Jagiello\u0144ski Collegium Medicum","ror":"https://ror.org/03bqmcz70"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2977700666.pdf","grobid_xml":"https://content.openalex.org/works/W2977700666.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W157808733","https://openalex.org/W175377976","https://openalex.org/W216878207","https://openalex.org/W1965555277","https://openalex.org/W1968194407","https://openalex.org/W1971948710","https://openalex.org/W1981045929","https://openalex.org/W1991001025","https://openalex.org/W1992532276","https://openalex.org/W1997937079","https://openalex.org/W2003580475","https://openalex.org/W2007796608","https://openalex.org/W2010084913","https://openalex.org/W2017422947","https://openalex.org/W2040127950","https://openalex.org/W2043391837","https://openalex.org/W2047647869","https://openalex.org/W2053364794","https://openalex.org/W2061762615","https://openalex.org/W2075040473","https://openalex.org/W2098640082","https://openalex.org/W2102220938","https://openalex.org/W2110114468","https://openalex.org/W2112174816","https://openalex.org/W2114441129","https://openalex.org/W2118408654","https://openalex.org/W2129328366","https://openalex.org/W2130479394","https://openalex.org/W2134067100","https://openalex.org/W2152375291","https://openalex.org/W2156954132","https://openalex.org/W2218549401","https://openalex.org/W2242664669","https://openalex.org/W2506390494","https://openalex.org/W2525612823","https://openalex.org/W2607474778","https://openalex.org/W2765673662","https://openalex.org/W2769315283","https://openalex.org/W2971836471","https://openalex.org/W4240895940","https://openalex.org/W4388314683","https://openalex.org/W6682929528"],"related_works":["https://openalex.org/W109877912","https://openalex.org/W1566328901","https://openalex.org/W2392521623","https://openalex.org/W34357983","https://openalex.org/W2770089535","https://openalex.org/W2018595005","https://openalex.org/W1976646060","https://openalex.org/W2059395758","https://openalex.org/W4251588189","https://openalex.org/W2184695179"],"abstract_inverted_index":{"The":[0,39,71],"solenoid":[1,21,74],"is":[2],"a":[3,12,43,52],"highly":[4],"ordered":[5,73],"structure":[6,80],"observed":[7],"in":[8,69,85],"proteins,":[9],"characterized":[10],"by":[11,51],"set":[13],"of":[14,18,31,58,64,81,90,95,98],"symmetries.":[15],"A":[16],"group":[17],"enzymes\u2014lyases":[19],"containing":[20],"fragments\u2014was":[22],"subjected":[23],"to":[24,102],"analysis":[25],"with":[26,106],"focus":[27],"on":[28,62],"their":[29],"distribution":[30,45],"hydrophobicity/hydrophilicity,":[32],"applying":[33],"the":[34,79,82,107],"fuzzy":[35],"oil":[36],"drop":[37],"model.":[38],"model":[40],"differentiates":[41],"between":[42],"monocentric":[44],"hydrophobic":[46],"core":[47],"(spherical":[48],"symmetry\u2014mathematically":[49],"modeled":[50],"3D":[53],"Gaussian)":[54],"and":[55],"linear":[56],"propagation":[57],"hydrophobicity":[59],"(symmetry":[60],"based":[61],"translation":[63],"structural":[65],"units,":[66],"i.e.,":[67],"chains\u2014evident":[68],"amyloids).":[70],"linearly":[72],"carries":[75],"information":[76],"that":[77],"affects":[78],"aqueous":[83],"solvent":[84],"its":[86,91],"neighborhood.":[87],"Progressive":[88],"disruption":[89],"symmetry":[92],"(via":[93],"incorporation":[94],"asymmetrical":[96],"fragments":[97],"varying":[99],"size)":[100],"appears":[101],"facilitate":[103],"selective":[104],"interaction":[105],"intended":[108],"substrate":[109],"during":[110],"enzymatic":[111],"catalysis.":[112]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-06-10T14:10:52.464848","created_date":"2025-10-10T00:00:00"}