{"id":"https://openalex.org/W2907639394","doi":"https://doi.org/10.3390/sym11010059","title":"Vertical Bone Construction with Bone Marrow-Derived and Adipose Tissue-Derived Stem Cells","display_name":"Vertical Bone Construction with Bone Marrow-Derived and Adipose Tissue-Derived Stem Cells","publication_year":2019,"publication_date":"2019-01-08","ids":{"openalex":"https://openalex.org/W2907639394","doi":"https://doi.org/10.3390/sym11010059","mag":"2907639394"},"language":"en","primary_location":{"id":"doi:10.3390/sym11010059","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym11010059","pdf_url":"https://www.mdpi.com/2073-8994/11/1/59/pdf?version=1546918376","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2073-8994/11/1/59/pdf?version=1546918376","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034065398","display_name":"Thaiz Carrera-Arrabal","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129940","display_name":"Faculdade S\u00e3o Leopoldo Mandic","ror":"https://ror.org/03m1j9m44","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210129940"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Thaiz Carrera-Arrabal","raw_affiliation_strings":["Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil"],"affiliations":[{"raw_affiliation_string":"Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil","institution_ids":["https://openalex.org/I4210129940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034074678","display_name":"Jos\u00e9 Lu\u00eds Calvo\u2010Guirado","orcid":"https://orcid.org/0000-0002-4067-2253"},"institutions":[{"id":"https://openalex.org/I68763199","display_name":"Universidad Cat\u00f3lica de Murcia","ror":"https://ror.org/05b1rsv17","country_code":"ES","type":"education","lineage":["https://openalex.org/I68763199"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Luis Calvo-Guirado","raw_affiliation_strings":["Department of Oral and Implant Surgery. Faculty of Health Sciences, Universidad Cat\u00f3lica San Antonio de Murcia (UCAM), 30002 Murcia, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Oral and Implant Surgery. Faculty of Health Sciences, Universidad Cat\u00f3lica San Antonio de Murcia (UCAM), 30002 Murcia, Spain","institution_ids":["https://openalex.org/I68763199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065108026","display_name":"Fabr\u00edcio Passador\u2010Santos","orcid":"https://orcid.org/0000-0003-2777-8640"},"institutions":[{"id":"https://openalex.org/I4210129940","display_name":"Faculdade S\u00e3o Leopoldo Mandic","ror":"https://ror.org/03m1j9m44","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210129940"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fabricio Passador-Santos","raw_affiliation_strings":["Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil"],"affiliations":[{"raw_affiliation_string":"Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil","institution_ids":["https://openalex.org/I4210129940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064023538","display_name":"Carlos Eduardo Sorgi da Costa","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129940","display_name":"Faculdade S\u00e3o Leopoldo Mandic","ror":"https://ror.org/03m1j9m44","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210129940"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carlos Eduardo Sorgi da Costa","raw_affiliation_strings":["Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil"],"affiliations":[{"raw_affiliation_string":"Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil","institution_ids":["https://openalex.org/I4210129940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110591239","display_name":"Frank R\u00f3ger Teles Costa","orcid":null},"institutions":[{"id":"https://openalex.org/I4210129940","display_name":"Faculdade S\u00e3o Leopoldo Mandic","ror":"https://ror.org/03m1j9m44","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210129940"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Frank R\u00f3ger Teles Costa","raw_affiliation_strings":["Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil"],"affiliations":[{"raw_affiliation_string":"Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil","institution_ids":["https://openalex.org/I4210129940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031076135","display_name":"Ant\u00f4nio Carlos Aloise","orcid":"https://orcid.org/0000-0002-9318-7956"},"institutions":[{"id":"https://openalex.org/I4210129940","display_name":"Faculdade S\u00e3o Leopoldo Mandic","ror":"https://ror.org/03m1j9m44","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210129940"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Antonio Carlos Aloise","raw_affiliation_strings":["Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil"],"affiliations":[{"raw_affiliation_string":"Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil","institution_ids":["https://openalex.org/I4210129940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053616519","display_name":"Marcelo Henrique Napimoga","orcid":"https://orcid.org/0000-0003-4472-365X"},"institutions":[{"id":"https://openalex.org/I4210129940","display_name":"Faculdade S\u00e3o Leopoldo Mandic","ror":"https://ror.org/03m1j9m44","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210129940"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcelo Henrique Napimoga","raw_affiliation_strings":["Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil"],"affiliations":[{"raw_affiliation_string":"Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil","institution_ids":["https://openalex.org/I4210129940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059923069","display_name":"Juan Manuel Aragoneses","orcid":"https://orcid.org/0000-0003-0187-4992"},"institutions":[{"id":"https://openalex.org/I3132841018","display_name":"Universidad Federico Henr\u00edquez y Carvajal","ror":"https://ror.org/0250t7374","country_code":"DO","type":"education","lineage":["https://openalex.org/I3132841018"]}],"countries":["DO"],"is_corresponding":false,"raw_author_name":"Juan Manuel Aragoneses","raw_affiliation_strings":["Department of Dental Research in Universidad Federico Henr\u00edquez y Carvajal (UFHEC), Santo Domingo 10107, Dominican Republic"],"affiliations":[{"raw_affiliation_string":"Department of Dental Research in Universidad Federico Henr\u00edquez y Carvajal (UFHEC), Santo Domingo 10107, Dominican Republic","institution_ids":["https://openalex.org/I3132841018"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009021794","display_name":"Andr\u00e9 Ant\u00f4nio Pelegrine","orcid":"https://orcid.org/0000-0001-7935-1062"},"institutions":[{"id":"https://openalex.org/I4210129940","display_name":"Faculdade S\u00e3o Leopoldo Mandic","ror":"https://ror.org/03m1j9m44","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210129940"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Andr\u00e9 Antonio Pelegrine","raw_affiliation_strings":["Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil"],"affiliations":[{"raw_affiliation_string":"Faculdade S\u00e3o Leopoldo Mandic, Instituto de Pesquisas S\u00e3o Leopoldo Mandic, Campinas 13045-755, Brazil","institution_ids":["https://openalex.org/I4210129940"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5009021794"],"corresponding_institution_ids":["https://openalex.org/I4210129940"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2165},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2165},"fwci":0.1426,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.50004676,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"11","issue":"1","first_page":"59","last_page":"59"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calvaria","display_name":"Calvaria","score":0.9582319259643555},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"Adipose tissue","score":0.7683308124542236},{"id":"https://openalex.org/keywords/stem-cell","display_name":"Stem cell","score":0.7062630653381348},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"Bone marrow","score":0.6484221816062927},{"id":"https://openalex.org/keywords/mesenchymal-stem-cell","display_name":"Mesenchymal stem cell","score":0.5046802759170532},{"id":"https://openalex.org/keywords/decortication","display_name":"Decortication","score":0.4610774517059326},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.41700413823127747},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.38623929023742676},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.34158849716186523},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2582412362098694},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2543468475341797},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.2534715533256531},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.19883587956428528},{"id":"https://openalex.org/keywords/in-vitro","display_name":"In vitro","score":0.06282511353492737}],"concepts":[{"id":"https://openalex.org/C2779918246","wikidata":"https://www.wikidata.org/wiki/Q613203","display_name":"Calvaria","level":3,"score":0.9582319259643555},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.7683308124542236},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.7062630653381348},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.6484221816062927},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.5046802759170532},{"id":"https://openalex.org/C2779688492","wikidata":"https://www.wikidata.org/wiki/Q1183720","display_name":"Decortication","level":2,"score":0.4610774517059326},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41700413823127747},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38623929023742676},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.34158849716186523},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2582412362098694},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2543468475341797},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2534715533256531},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.19883587956428528},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06282511353492737},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3390/sym11010059","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym11010059","pdf_url":"https://www.mdpi.com/2073-8994/11/1/59/pdf?version=1546918376","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:762cd4aefd1e4940add97dd63e4f3afe","is_oa":true,"landing_page_url":"https://doaj.org/article/762cd4aefd1e4940add97dd63e4f3afe","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Symmetry, Vol 11, Iss 1, p 59 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/sym11010059","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sym11010059","pdf_url":"https://www.mdpi.com/2073-8994/11/1/59/pdf?version=1546918376","source":{"id":"https://openalex.org/S190787756","display_name":"Symmetry","issn_l":"2073-8994","issn":["2073-8994"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Symmetry","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2907639394.pdf","grobid_xml":"https://content.openalex.org/works/W2907639394.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W190856078","https://openalex.org/W1059435133","https://openalex.org/W1859756429","https://openalex.org/W1965425745","https://openalex.org/W1975156603","https://openalex.org/W1982498935","https://openalex.org/W1986989201","https://openalex.org/W1998614074","https://openalex.org/W2000059488","https://openalex.org/W2007335169","https://openalex.org/W2008737522","https://openalex.org/W2025371271","https://openalex.org/W2059204309","https://openalex.org/W2083284583","https://openalex.org/W2087993338","https://openalex.org/W2097400727","https://openalex.org/W2102169821","https://openalex.org/W2106050448","https://openalex.org/W2163453356","https://openalex.org/W2168864326","https://openalex.org/W2220957903","https://openalex.org/W2314343334","https://openalex.org/W2330409768","https://openalex.org/W2334142778","https://openalex.org/W2550999974","https://openalex.org/W2620958337","https://openalex.org/W2782447519","https://openalex.org/W2947147959","https://openalex.org/W6738501043"],"related_works":["https://openalex.org/W2709958867","https://openalex.org/W2089548588","https://openalex.org/W2061596329","https://openalex.org/W2333776778","https://openalex.org/W2373218030","https://openalex.org/W3032040701","https://openalex.org/W2384982620","https://openalex.org/W2024479894","https://openalex.org/W2408669669","https://openalex.org/W2165852945"],"abstract_inverted_index":{"The":[0,46,53,118,134],"purpose":[1],"of":[2,11,42,74,95],"this":[3],"study":[4],"was":[5],"to":[6,203],"conduct":[7],"a":[8,21],"histomorphometric":[9,116,135],"analysis":[10,136],"bone":[12,26,59,66,124,198,209,229],"marrow-derived":[13,60,199],"and":[14,105,130,141,150,156,160,169,179],"adipose":[15,80,87,214],"tissue-derived":[16,81,215],"stem":[17,62,68,83,89,200,216],"cells,":[18],"associated":[19],"with":[20,50,57,78,172,222],"xenograft":[22,35],"block,":[23],"in":[24,28,64,85,111,166,176,188,220,226],"vertical":[25,228],"constructions":[27],"rabbit":[29],"calvaria.":[30],"Ten":[31],"rabbits":[32],"received":[33],"two":[34],"blocks":[36,47,54,225],"on":[37],"the":[38,43,58,65,75,79,86,96,101,115,177,180,183,189,197,208,213,223,227],"calvaria,":[39],"after":[40],"decortication":[41],"parietal":[44,107],"bone.":[45],"were":[48,55,103,109,121],"fixed":[49,110],"titanium":[51],"screws.":[52],"combined":[56],"mesenchymal":[61,82],"cells":[63,84,201,217],"marrow":[67],"cell":[69,90],"(BMSC)":[70],"group":[71,92],"(right":[72],"side":[73,94],"calvaria)":[76],"or":[77],"tissue":[88,132],"(ATSC)":[91],"(left":[93],"calvaria).":[97],"After":[98],"8":[99],"weeks,":[100],"animals":[102],"sacrificed":[104],"their":[106],"bones":[108],"10%":[112],"formalin":[113],"for":[114,145,154,164,207],"analysis.":[117],"following":[119],"parameters":[120],"evaluated\u2014newly":[122],"formed":[123],"(NFB),":[125],"xenogeneic":[126],"residual":[127],"particles":[128],"(XRP),":[129],"non-mineralized":[131],"(NMT).":[133],"revealed":[137],"11.9":[138],"\u00b1":[139,143,148,152,158,162],"7.5%":[140],"7.6":[142],"5.6%":[144],"NFB,":[146],"22.14":[147],"8.5%":[149,153],"21.6":[151],"XRP,":[155],"65.8":[157],"10.4%":[159],"70.8":[161],"7.4%":[163],"NMT":[165,181],"groups":[167],"BMSC":[168],"ATSC,":[170],"respectively,":[171],"statistically":[173],"significant":[174],"differences":[175,187],"NFB":[178],"between":[182],"groups,":[184],"but":[185],"no":[186],"XRP.":[190],"Therefore,":[191],"it":[192],"can":[193],"be":[194],"concluded":[195],"that":[196],"seem":[202],"have":[204],"more":[205],"potential":[206],"formation":[210],"than":[211],"do":[212],"when":[218],"used":[219],"combination":[221],"xenogenous":[224],"construction.":[230]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}