{"id":"https://openalex.org/W2132828648","doi":"https://doi.org/10.3390/s90806471","title":"Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity","display_name":"Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity","publication_year":2009,"publication_date":"2009-08-20","ids":{"openalex":"https://openalex.org/W2132828648","doi":"https://doi.org/10.3390/s90806471","mag":"2132828648","pmid":"https://pubmed.ncbi.nlm.nih.gov/22454596"},"language":"en","primary_location":{"id":"doi:10.3390/s90806471","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s90806471","pdf_url":"https://www.mdpi.com/1424-8220/9/8/6471/pdf?version=1403311658","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/9/8/6471/pdf?version=1403311658","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023138915","display_name":"Marco Rusnati","orcid":"https://orcid.org/0000-0001-9968-5908"},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Marco Rusnati","raw_affiliation_strings":["Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","institution_ids":["https://openalex.org/I79940851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011403015","display_name":"Antonella Bugatti","orcid":"https://orcid.org/0000-0001-5450-5774"},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonella Bugatti","raw_affiliation_strings":["Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","E-Mails:  rusnati@med.unibs.it  (M.R.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","institution_ids":["https://openalex.org/I79940851"]},{"raw_affiliation_string":"E-Mails:  rusnati@med.unibs.it  (M.R.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053652045","display_name":"Stefania Mitola","orcid":"https://orcid.org/0000-0002-5557-738X"},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefania Mitola","raw_affiliation_strings":["Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","bugatti@med.unibs.it  (A.B.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","institution_ids":["https://openalex.org/I79940851"]},{"raw_affiliation_string":"bugatti@med.unibs.it  (A.B.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052540458","display_name":"Daria Leali","orcid":null},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Daria Leali","raw_affiliation_strings":["Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","mitola@med.unibs.it  (S.M.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","institution_ids":["https://openalex.org/I79940851"]},{"raw_affiliation_string":"mitola@med.unibs.it  (S.M.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000990562","display_name":"Paolo Bergese","orcid":"https://orcid.org/0000-0002-4652-2168"},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Bergese","raw_affiliation_strings":["Chemistry for Technologies Laboratory and Department of Mechanical and Industrial Engineering, School of Engineering, University of Brescia, Brescia, 25123, Italy","leali@med.unibs.it  (D.L.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry for Technologies Laboratory and Department of Mechanical and Industrial Engineering, School of Engineering, University of Brescia, Brescia, 25123, Italy","institution_ids":["https://openalex.org/I79940851"]},{"raw_affiliation_string":"leali@med.unibs.it  (D.L.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043051527","display_name":"Laura E. Depero","orcid":"https://orcid.org/0000-0001-7818-3212"},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura E. Depero","raw_affiliation_strings":["Chemistry for Technologies Laboratory and Department of Mechanical and Industrial Engineering, School of Engineering, University of Brescia, Brescia, 25123, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry for Technologies Laboratory and Department of Mechanical and Industrial Engineering, School of Engineering, University of Brescia, Brescia, 25123, Italy","institution_ids":["https://openalex.org/I79940851"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005942566","display_name":"Marco Presta","orcid":"https://orcid.org/0000-0002-4398-8376"},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Presta","raw_affiliation_strings":["Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, 25123, Italy","institution_ids":["https://openalex.org/I79940851"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5023138915"],"corresponding_institution_ids":["https://openalex.org/I79940851"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":0.5472,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.67649413,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"9","issue":"8","first_page":"6471","last_page":"6503"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12287","display_name":"Fibroblast Growth Factor Research","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fibroblast-growth-factor","display_name":"Fibroblast growth factor","score":0.8016536235809326},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"Angiogenesis","score":0.772098183631897},{"id":"https://openalex.org/keywords/neovascularization","display_name":"Neovascularization","score":0.6499987840652466},{"id":"https://openalex.org/keywords/surface-plasmon-resonance","display_name":"Surface plasmon resonance","score":0.6369725465774536},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.46333375573158264},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.44893771409988403},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.40927499532699585},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.35059505701065063},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.28739815950393677},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2147780954837799},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.20668897032737732},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.19808340072631836}],"concepts":[{"id":"https://openalex.org/C74373430","wikidata":"https://www.wikidata.org/wiki/Q24727126","display_name":"Fibroblast growth factor","level":3,"score":0.8016536235809326},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.772098183631897},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.6499987840652466},{"id":"https://openalex.org/C106847996","wikidata":"https://www.wikidata.org/wiki/Q898756","display_name":"Surface plasmon resonance","level":3,"score":0.6369725465774536},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.46333375573158264},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44893771409988403},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40927499532699585},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.35059505701065063},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28739815950393677},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2147780954837799},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.20668897032737732},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.19808340072631836},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/s90806471","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s90806471","pdf_url":"https://www.mdpi.com/1424-8220/9/8/6471/pdf?version=1403311658","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:22454596","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22454596","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:0e6ae45f7a5745fa8573b22388d87b0a","is_oa":true,"landing_page_url":"https://doaj.org/article/0e6ae45f7a5745fa8573b22388d87b0a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 9, Iss 8, Pp 6471-6503 (2009)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2318095","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3312455","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:iris.unibs.it:11379/28438","is_oa":false,"landing_page_url":"http://hdl.handle.net/11379/28438","pdf_url":null,"source":{"id":"https://openalex.org/S4306400804","display_name":"Institutional Research Information System (Universit\u00e0 degli Studi di Brescia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/s90806471","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s90806471","pdf_url":"https://www.mdpi.com/1424-8220/9/8/6471/pdf?version=1403311658","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5199999809265137}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321499","display_name":"Fondazione Cariplo","ror":"https://ror.org/01gb56c55"},{"id":"https://openalex.org/F4320322278","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432"},{"id":"https://openalex.org/F4320323054","display_name":"Associazione Italiana per la Ricerca sul Cancro","ror":"https://ror.org/02g2x7380"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2132828648.pdf","grobid_xml":"https://content.openalex.org/works/W2132828648.grobid-xml"},"referenced_works_count":194,"referenced_works":["https://openalex.org/W69667449","https://openalex.org/W260287336","https://openalex.org/W1490146269","https://openalex.org/W1494551606","https://openalex.org/W1495287184","https://openalex.org/W1500274227","https://openalex.org/W1503786837","https://openalex.org/W1512706674","https://openalex.org/W1513451331","https://openalex.org/W1514571277","https://openalex.org/W1567875677","https://openalex.org/W1573363574","https://openalex.org/W1578995377","https://openalex.org/W1608448958","https://openalex.org/W1650277859","https://openalex.org/W1818290857","https://openalex.org/W1959188680","https://openalex.org/W1963805168","https://openalex.org/W1963805383","https://openalex.org/W1964417650","https://openalex.org/W1966514861","https://openalex.org/W1968139322","https://openalex.org/W1968249815","https://openalex.org/W1968321554","https://openalex.org/W1969144485","https://openalex.org/W1970578871","https://openalex.org/W1972855766","https://openalex.org/W1974472983","https://openalex.org/W1975646137","https://openalex.org/W1975785300","https://openalex.org/W1975837985","https://openalex.org/W1977378497","https://openalex.org/W1977657343","https://openalex.org/W1977672375","https://openalex.org/W1980438007","https://openalex.org/W1981124196","https://openalex.org/W1983580477","https://openalex.org/W1986547423","https://openalex.org/W1987092452","https://openalex.org/W1987743697","https://openalex.org/W1991326807","https://openalex.org/W1992427262","https://openalex.org/W1994674148","https://openalex.org/W1994874248","https://openalex.org/W1994979141","https://openalex.org/W1995464852","https://openalex.org/W1996642042","https://openalex.org/W1996711684","https://openalex.org/W1998744280","https://openalex.org/W1998767340","https://openalex.org/W2000000541","https://openalex.org/W2001343980","https://openalex.org/W2001610172","https://openalex.org/W2002396741","https://openalex.org/W2003637780","https://openalex.org/W2006188134","https://openalex.org/W2007863359","https://openalex.org/W2008906677","https://openalex.org/W2009080634","https://openalex.org/W2010897035","https://openalex.org/W2014438788","https://openalex.org/W2014618196","https://openalex.org/W2016240486","https://openalex.org/W2017022268","https://openalex.org/W2018449597","https://openalex.org/W2018885671","https://openalex.org/W2019061836","https://openalex.org/W2019555687","https://openalex.org/W2019981734","https://openalex.org/W2022605219","https://openalex.org/W2023435727","https://openalex.org/W2023609799","https://openalex.org/W2025979213","https://openalex.org/W2027172024","https://openalex.org/W2027261163","https://openalex.org/W2029071081","https://openalex.org/W2031655517","https://openalex.org/W2032508585","https://openalex.org/W2033945189","https://openalex.org/W2035069575","https://openalex.org/W2035248906","https://openalex.org/W2036002472","https://openalex.org/W2036765487","https://openalex.org/W2040537095","https://openalex.org/W2046356130","https://openalex.org/W2046826062","https://openalex.org/W2049516409","https://openalex.org/W2049612319","https://openalex.org/W2049903695","https://openalex.org/W2050518514","https://openalex.org/W2051478187","https://openalex.org/W2052997177","https://openalex.org/W2053247155","https://openalex.org/W2053487601","https://openalex.org/W2054578983","https://openalex.org/W2054965394","https://openalex.org/W2055566195","https://openalex.org/W2056244879","https://openalex.org/W2056983875","https://openalex.org/W2058525519","https://openalex.org/W2058773995","https://openalex.org/W2059612050","https://openalex.org/W2060701737","https://openalex.org/W2061230824","https://openalex.org/W2061402441","https://openalex.org/W2061669497","https://openalex.org/W2062538312","https://openalex.org/W2062680870","https://openalex.org/W2062752859","https://openalex.org/W2063184759","https://openalex.org/W2063648669","https://openalex.org/W2064777789","https://openalex.org/W2068984130","https://openalex.org/W2075500765","https://openalex.org/W2076415360","https://openalex.org/W2078464742","https://openalex.org/W2078875435","https://openalex.org/W2080062167","https://openalex.org/W2080264482","https://openalex.org/W2081948547","https://openalex.org/W2083461824","https://openalex.org/W2084830265","https://openalex.org/W2085845774","https://openalex.org/W2086234005","https://openalex.org/W2088684743","https://openalex.org/W2090093512","https://openalex.org/W2091866599","https://openalex.org/W2094892410","https://openalex.org/W2095113001","https://openalex.org/W2095577681","https://openalex.org/W2095861370","https://openalex.org/W2099021208","https://openalex.org/W2099146799","https://openalex.org/W2100525694","https://openalex.org/W2109489238","https://openalex.org/W2110192298","https://openalex.org/W2111092458","https://openalex.org/W2114297048","https://openalex.org/W2116715149","https://openalex.org/W2121119720","https://openalex.org/W2121589151","https://openalex.org/W2121807107","https://openalex.org/W2122407131","https://openalex.org/W2123080551","https://openalex.org/W2126108426","https://openalex.org/W2126419751","https://openalex.org/W2129250883","https://openalex.org/W2129307844","https://openalex.org/W2129440725","https://openalex.org/W2130459735","https://openalex.org/W2130795109","https://openalex.org/W2135296230","https://openalex.org/W2138129757","https://openalex.org/W2144328981","https://openalex.org/W2144780216","https://openalex.org/W2148745019","https://openalex.org/W2152522313","https://openalex.org/W2158062848","https://openalex.org/W2160325573","https://openalex.org/W2161638912","https://openalex.org/W2162072149","https://openalex.org/W2162614168","https://openalex.org/W2163933974","https://openalex.org/W2163953306","https://openalex.org/W2164512506","https://openalex.org/W2169120384","https://openalex.org/W2172534769","https://openalex.org/W2253635263","https://openalex.org/W2257907717","https://openalex.org/W2322559858","https://openalex.org/W2329203817","https://openalex.org/W2398839343","https://openalex.org/W2403815535","https://openalex.org/W2409929769","https://openalex.org/W2414765784","https://openalex.org/W2416019065","https://openalex.org/W4210966619","https://openalex.org/W4211028838","https://openalex.org/W4211073935","https://openalex.org/W4211085156","https://openalex.org/W4211153659","https://openalex.org/W4211210676","https://openalex.org/W4235948748","https://openalex.org/W4239103237","https://openalex.org/W4242478724","https://openalex.org/W6630769440","https://openalex.org/W6641079023","https://openalex.org/W6665032629","https://openalex.org/W6665728057","https://openalex.org/W6666558201","https://openalex.org/W6674991618","https://openalex.org/W6684025593","https://openalex.org/W6691859295","https://openalex.org/W6714727275"],"related_works":["https://openalex.org/W2104752154","https://openalex.org/W2414879916","https://openalex.org/W2460667757","https://openalex.org/W2051449188","https://openalex.org/W73242545","https://openalex.org/W2114498041","https://openalex.org/W1946062636","https://openalex.org/W13443198","https://openalex.org/W2146672236","https://openalex.org/W53666519"],"abstract_inverted_index":{"Angiogenesis,":[0],"the":[1,64,100,111],"process":[2],"of":[3,113],"new":[4],"blood":[5],"vessel":[6],"formation,":[7],"is":[8,25,41],"implicated":[9],"in":[10,32,63,81,95],"various":[11,33],"physiological/pathological":[12],"conditions,":[13],"including":[14,36],"embryonic":[15],"development,":[16],"inflammation":[17],"and":[18,60],"tumor":[19,37],"growth.":[20],"Fibroblast":[21],"growth":[22,29],"factor-2":[23],"(FGF2)":[24],"a":[26,43,106],"heparin-binding":[27],"angiogenic":[28],"factor":[30],"involved":[31],"physiopathological":[34],"processes,":[35],"neovascularization.":[38],"Accordingly,":[39],"FGF2":[40,62,85],"considered":[42],"target":[44],"for":[45,55,83,110],"antiangiogenic":[46,84,114],"therapies.":[47],"Thus,":[48],"numerous":[49],"natural/synthetic":[50],"compounds":[51],"have":[52,74],"been":[53],"tested":[54],"their":[56],"capacity":[57],"to":[58,102],"bind":[59],"sequester":[61],"extracellular":[65],"environment":[66],"preventing":[67],"its":[68],"interaction":[69],"with":[70,99],"cellular":[71],"receptors.":[72],"We":[73],"exploited":[75],"surface":[76],"plasmon":[77],"resonance":[78],"(SPR)":[79],"technique":[80],"search":[82],"binders/antagonists.":[86],"In":[87],"this":[88],"review":[89],"we":[90],"will":[91],"summarize":[92],"our":[93],"experience":[94],"SPR-based":[96],"angiogenesis":[97],"research,":[98],"aim":[101],"validate":[103],"SPR":[104],"as":[105],"first":[107],"line":[108],"screening":[109],"identification":[112],"compounds.":[115]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}