{"id":"https://openalex.org/W1993231248","doi":"https://doi.org/10.3390/s90503713","title":"Nucleic Acid-based Detection of Bacterial Pathogens Using Integrated Microfluidic Platform Systems","display_name":"Nucleic Acid-based Detection of Bacterial Pathogens Using Integrated Microfluidic Platform Systems","publication_year":2009,"publication_date":"2009-05-18","ids":{"openalex":"https://openalex.org/W1993231248","doi":"https://doi.org/10.3390/s90503713","mag":"1993231248","pmid":"https://pubmed.ncbi.nlm.nih.gov/22412335"},"language":"en","primary_location":{"id":"doi:10.3390/s90503713","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s90503713","pdf_url":"https://www.mdpi.com/1424-8220/9/5/3713/pdf?version=1403311487","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/9/5/3713/pdf?version=1403311487","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054534707","display_name":"Clarissa Lui","orcid":null},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clarissa Lui","raw_affiliation_strings":["Department of Biomedical Engineering / Cornell University, 317 Stocking Hall, Ithaca, NY 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering / Cornell University, 317 Stocking Hall, Ithaca, NY 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046312510","display_name":"Nathaniel C. Cady","orcid":"https://orcid.org/0000-0003-4345-3627"},"institutions":[{"id":"https://openalex.org/I113508548","display_name":"Albany State University","ror":"https://ror.org/01vme4277","country_code":"US","type":"education","lineage":["https://openalex.org/I113508548"]},{"id":"https://openalex.org/I392282","display_name":"University at Albany, State University of New York","ror":"https://ror.org/012zs8222","country_code":"US","type":"education","lineage":["https://openalex.org/I392282"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathaniel  C. Cady","raw_affiliation_strings":["College of Nanoscale Science and Engineering / University at Albany State University of New York, 255 Fuller Rd., Albany, NY 12203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Nanoscale Science and Engineering / University at Albany State University of New York, 255 Fuller Rd., Albany, NY 12203, USA","institution_ids":["https://openalex.org/I113508548","https://openalex.org/I392282"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112416559","display_name":"Carl A. Batt","orcid":null},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carl  A. Batt","raw_affiliation_strings":["Department of Food Science / Cornell University, 312 Stocking Hall, Ithaca, NY 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science / Cornell University, 312 Stocking Hall, Ithaca, NY 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":6.43,"has_fulltext":true,"cited_by_count":116,"citation_normalized_percentile":{"value":0.96721634,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"9","issue":"5","first_page":"3713","last_page":"3744"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.6993684768676758},{"id":"https://openalex.org/keywords/miniaturization","display_name":"Miniaturization","score":0.6079200506210327},{"id":"https://openalex.org/keywords/nucleic-acid-detection","display_name":"Nucleic acid detection","score":0.586864173412323},{"id":"https://openalex.org/keywords/nucleic-acid","display_name":"Nucleic acid","score":0.5497314929962158},{"id":"https://openalex.org/keywords/automation","display_name":"Automation","score":0.47601157426834106},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.44978368282318115},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3872458040714264},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.23640140891075134},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.16957083344459534},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.10783722996711731}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.6993684768676758},{"id":"https://openalex.org/C57528182","wikidata":"https://www.wikidata.org/wiki/Q1271842","display_name":"Miniaturization","level":2,"score":0.6079200506210327},{"id":"https://openalex.org/C2910367586","wikidata":"https://www.wikidata.org/wiki/Q348667","display_name":"Nucleic acid detection","level":3,"score":0.586864173412323},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.5497314929962158},{"id":"https://openalex.org/C115901376","wikidata":"https://www.wikidata.org/wiki/Q184199","display_name":"Automation","level":2,"score":0.47601157426834106},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.44978368282318115},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3872458040714264},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.23640140891075134},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16957083344459534},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.10783722996711731},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/s90503713","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s90503713","pdf_url":"https://www.mdpi.com/1424-8220/9/5/3713/pdf?version=1403311487","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:22412335","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22412335","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.272.102","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.272.102","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/bf/84/Sensors_(Basel)_2009_May_18_9(5)_3713-3744.tar.gz","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:8febcbdfb7614e1e97dc895788fb5254","is_oa":true,"landing_page_url":"https://doaj.org/article/8febcbdfb7614e1e97dc895788fb5254","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 9, Iss 5, Pp 3713-3744 (2009)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1424-8220/9/5/3713/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s90503713","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 9; Issue 5; Pages: 3713-3744","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3297159","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3297159","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s90503713","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s90503713","pdf_url":"https://www.mdpi.com/1424-8220/9/5/3713/pdf?version=1403311487","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1993231248.pdf","grobid_xml":"https://content.openalex.org/works/W1993231248.grobid-xml"},"referenced_works_count":176,"referenced_works":["https://openalex.org/W34419914","https://openalex.org/W40848248","https://openalex.org/W49147553","https://openalex.org/W179557849","https://openalex.org/W397136504","https://openalex.org/W1555946919","https://openalex.org/W1590106897","https://openalex.org/W1964597866","https://openalex.org/W1964923290","https://openalex.org/W1966073229","https://openalex.org/W1966323177","https://openalex.org/W1966712125","https://openalex.org/W1968541773","https://openalex.org/W1968583263","https://openalex.org/W1969442216","https://openalex.org/W1969604868","https://openalex.org/W1970592466","https://openalex.org/W1971056653","https://openalex.org/W1972212476","https://openalex.org/W1974622938","https://openalex.org/W1975049174","https://openalex.org/W1975388324","https://openalex.org/W1975687263","https://openalex.org/W1975872110","https://openalex.org/W1976320478","https://openalex.org/W1978683040","https://openalex.org/W1978892497","https://openalex.org/W1979294051","https://openalex.org/W1981112525","https://openalex.org/W1982179033","https://openalex.org/W1984097742","https://openalex.org/W1984857185","https://openalex.org/W1985718165","https://openalex.org/W1986990357","https://openalex.org/W1995656159","https://openalex.org/W1997462777","https://openalex.org/W1997887128","https://openalex.org/W2000608441","https://openalex.org/W2000683678","https://openalex.org/W2001316885","https://openalex.org/W2001847780","https://openalex.org/W2001977516","https://openalex.org/W2002213641","https://openalex.org/W2002609238","https://openalex.org/W2002805769","https://openalex.org/W2002808856","https://openalex.org/W2004698781","https://openalex.org/W2009885588","https://openalex.org/W2010598840","https://openalex.org/W2010689416","https://openalex.org/W2012150207","https://openalex.org/W2014268977","https://openalex.org/W2014413829","https://openalex.org/W2018683972","https://openalex.org/W2020438216","https://openalex.org/W2021161855","https://openalex.org/W2026543268","https://openalex.org/W2028861967","https://openalex.org/W2029121329","https://openalex.org/W2029732784","https://openalex.org/W2030552522","https://openalex.org/W2032215280","https://openalex.org/W2032499269","https://openalex.org/W2034488599","https://openalex.org/W2034758188","https://openalex.org/W2035666431","https://openalex.org/W2036705801","https://openalex.org/W2037586865","https://openalex.org/W2037861870","https://openalex.org/W2037865481","https://openalex.org/W2038637564","https://openalex.org/W2039750959","https://openalex.org/W2041014993","https://openalex.org/W2042477811","https://openalex.org/W2046043028","https://openalex.org/W2046207977","https://openalex.org/W2047771911","https://openalex.org/W2048197073","https://openalex.org/W2049181488","https://openalex.org/W2050488696","https://openalex.org/W2050515344","https://openalex.org/W2050516283","https://openalex.org/W2050717506","https://openalex.org/W2051230121","https://openalex.org/W2052517586","https://openalex.org/W2053100086","https://openalex.org/W2054241320","https://openalex.org/W2054825107","https://openalex.org/W2055670545","https://openalex.org/W2056645539","https://openalex.org/W2057026305","https://openalex.org/W2058553857","https://openalex.org/W2060181267","https://openalex.org/W2063064357","https://openalex.org/W2065025290","https://openalex.org/W2070288110","https://openalex.org/W2070378283","https://openalex.org/W2071507584","https://openalex.org/W2072142132","https://openalex.org/W2073389192","https://openalex.org/W2074682130","https://openalex.org/W2074787925","https://openalex.org/W2078023294","https://openalex.org/W2078540772","https://openalex.org/W2079051055","https://openalex.org/W2079438065","https://openalex.org/W2080416055","https://openalex.org/W2080454873","https://openalex.org/W2080730737","https://openalex.org/W2080754367","https://openalex.org/W2080952359","https://openalex.org/W2082437135","https://openalex.org/W2082544764","https://openalex.org/W2082828982","https://openalex.org/W2083370524","https://openalex.org/W2083379719","https://openalex.org/W2083695757","https://openalex.org/W2085780879","https://openalex.org/W2087380772","https://openalex.org/W2088100868","https://openalex.org/W2089976786","https://openalex.org/W2090983970","https://openalex.org/W2091706583","https://openalex.org/W2095886050","https://openalex.org/W2096767229","https://openalex.org/W2097780256","https://openalex.org/W2097855301","https://openalex.org/W2098764494","https://openalex.org/W2098990516","https://openalex.org/W2099674028","https://openalex.org/W2100678992","https://openalex.org/W2102616257","https://openalex.org/W2107580398","https://openalex.org/W2107657366","https://openalex.org/W2109744701","https://openalex.org/W2110778204","https://openalex.org/W2116208923","https://openalex.org/W2116364693","https://openalex.org/W2118030566","https://openalex.org/W2119229619","https://openalex.org/W2119399232","https://openalex.org/W2121296593","https://openalex.org/W2121484578","https://openalex.org/W2123957935","https://openalex.org/W2124449950","https://openalex.org/W2126052364","https://openalex.org/W2133149764","https://openalex.org/W2133882340","https://openalex.org/W2134667113","https://openalex.org/W2140620182","https://openalex.org/W2141497897","https://openalex.org/W2144498825","https://openalex.org/W2145957743","https://openalex.org/W2146771927","https://openalex.org/W2149495017","https://openalex.org/W2150519551","https://openalex.org/W2150985684","https://openalex.org/W2155380898","https://openalex.org/W2162046649","https://openalex.org/W2162687612","https://openalex.org/W2163208732","https://openalex.org/W2166099222","https://openalex.org/W2168611191","https://openalex.org/W2169593348","https://openalex.org/W2198973842","https://openalex.org/W2236551253","https://openalex.org/W2415247704","https://openalex.org/W2810630872","https://openalex.org/W3119390499","https://openalex.org/W3152443858","https://openalex.org/W4213060373","https://openalex.org/W4237521406","https://openalex.org/W4248033625","https://openalex.org/W6602019834","https://openalex.org/W6644972387","https://openalex.org/W6649833184"],"related_works":["https://openalex.org/W4299585159","https://openalex.org/W2272547605","https://openalex.org/W3031503986","https://openalex.org/W3131875014","https://openalex.org/W36135598","https://openalex.org/W1543504406","https://openalex.org/W2322221118","https://openalex.org/W4210872575","https://openalex.org/W2899696050","https://openalex.org/W2562142047"],"abstract_inverted_index":{"The":[0,24],"advent":[1],"of":[2,20,28,60,68,94],"nucleic":[3,51],"acid-based":[4,52],"pathogen":[5],"detection":[6,30,59,84],"methods":[7],"offers":[8],"increased":[9],"sensitivity":[10],"and":[11,26,48,77,82,90],"specificity":[12],"over":[13],"traditional":[14],"microbiological":[15],"techniques,":[16],"driving":[17],"the":[18,58,66],"development":[19],"portable,":[21],"integrated":[22,29,96],"biosensors.":[23],"miniaturization":[25,67],"automation":[27],"systems":[31,56],"presents":[32],"a":[33],"significant":[34],"advantage":[35],"for":[36,57,72,92],"rapid,":[37],"portable":[38,97],"field-based":[39],"testing.":[40],"In":[41],"this":[42],"review,":[43],"we":[44],"highlight":[45],"current":[46],"developments":[47],"directions":[49],"in":[50,65],"micro":[53],"total":[54],"analysis":[55],"bacterial":[61],"pathogens.":[62],"Recent":[63],"progress":[64],"microfluidic":[69],"processing":[70],"steps":[71],"cell":[73],"capture,":[74],"DNA":[75],"extraction":[76],"purification,":[78],"polymerase":[79],"chain":[80],"reaction,":[81],"product":[83],"are":[85],"detailed.":[86],"Discussions":[87],"include":[88],"strategies":[89],"challenges":[91],"implementation":[93],"an":[95],"platform.":[98]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":14}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}