{"id":"https://openalex.org/W4398777260","doi":"https://doi.org/10.3390/s24113383","title":"Development of an Optical System for Strain Drop Measurement of Osteosarcoma Cells on Substrates with Different Stiffness","display_name":"Development of an Optical System for Strain Drop Measurement of Osteosarcoma Cells on Substrates with Different Stiffness","publication_year":2024,"publication_date":"2024-05-24","ids":{"openalex":"https://openalex.org/W4398777260","doi":"https://doi.org/10.3390/s24113383"},"language":"en","primary_location":{"id":"doi:10.3390/s24113383","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s24113383","pdf_url":"https://www.mdpi.com/1424-8220/24/11/3383/pdf?version=1716556017","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/24/11/3383/pdf?version=1716556017","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086994002","display_name":"Ludovica Apa","orcid":"https://orcid.org/0000-0002-4249-5596"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ludovica Apa","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111272133","display_name":"Maria Vittoria Martire","orcid":null},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Vittoria Martire","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029915319","display_name":"Serena Carraro","orcid":"https://orcid.org/0000-0002-4649-6238"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Serena Carraro","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036434424","display_name":"Marianna Cosentino","orcid":"https://orcid.org/0000-0002-8745-2469"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marianna Cosentino","raw_affiliation_strings":["DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, 00161 Rome, Italy"],"affiliations":[{"raw_affiliation_string":"DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, 00161 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016949200","display_name":"Zaccaria Del Prete","orcid":"https://orcid.org/0000-0001-6057-7774"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Zaccaria Del Prete","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047968877","display_name":"Barbara Peruzzi","orcid":"https://orcid.org/0000-0003-1820-5816"},"institutions":[{"id":"https://openalex.org/I4210123352","display_name":"Bambino Ges\u00f9 Children's Hospital","ror":"https://ror.org/02sy42d13","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210123352","https://openalex.org/I4210153126"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Barbara Peruzzi","raw_affiliation_strings":["Bone Physiopathology Research Unit, Bambino Ges\u00f9 Children\u2019s Hospital, IRCCS, 00146 Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Bone Physiopathology Research Unit, Bambino Ges\u00f9 Children\u2019s Hospital, IRCCS, 00146 Rome, Italy","institution_ids":["https://openalex.org/I4210123352","https://openalex.org/I4210153126"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064007911","display_name":"Emanuele Rizzuto","orcid":"https://orcid.org/0000-0003-2314-6128"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Emanuele Rizzuto","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5064007911"],"corresponding_institution_ids":["https://openalex.org/I861853513"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":0.636,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.6495733,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"24","issue":"11","first_page":"3383","last_page":"3383"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stiffness","display_name":"Stiffness","score":0.6861457824707031},{"id":"https://openalex.org/keywords/osteosarcoma","display_name":"Osteosarcoma","score":0.6511895656585693},{"id":"https://openalex.org/keywords/drop","display_name":"Drop (telecommunication)","score":0.6119129657745361},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5297514200210571},{"id":"https://openalex.org/keywords/strain","display_name":"Strain (injury)","score":0.5204225182533264},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.41712239384651184},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.36299434304237366},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.3295857906341553},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.2627297043800354},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.24249997735023499},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15879499912261963},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.15289968252182007},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.09519991278648376}],"concepts":[{"id":"https://openalex.org/C2779372316","wikidata":"https://www.wikidata.org/wiki/Q569057","display_name":"Stiffness","level":2,"score":0.6861457824707031},{"id":"https://openalex.org/C2777760704","wikidata":"https://www.wikidata.org/wiki/Q549534","display_name":"Osteosarcoma","level":2,"score":0.6511895656585693},{"id":"https://openalex.org/C2781345722","wikidata":"https://www.wikidata.org/wiki/Q5308388","display_name":"Drop (telecommunication)","level":2,"score":0.6119129657745361},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5297514200210571},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.5204225182533264},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.41712239384651184},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.36299434304237366},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.3295857906341553},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.2627297043800354},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.24249997735023499},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15879499912261963},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.15289968252182007},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.09519991278648376}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/s24113383","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s24113383","pdf_url":"https://www.mdpi.com/1424-8220/24/11/3383/pdf?version=1716556017","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmh:oai:iris.uniroma1.it:11573/1712884","is_oa":true,"landing_page_url":"https://hdl.handle.net/11573/1712884","pdf_url":"https://iris.uniroma1.it/bitstream/11573/1712884/1/Apa_Development_2024.pdf","source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11175146","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11175146","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11175146/pdf/sensors-24-03383.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:18de9ca8306941018f93902c4590c9bd","is_oa":true,"landing_page_url":"https://doaj.org/article/18de9ca8306941018f93902c4590c9bd","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 24, Iss 11, p 3383 (2024)","raw_type":"article"},{"id":"pmh:oai:publicatt.unicatt.it:10807/304338","is_oa":true,"landing_page_url":"https://hdl.handle.net/10807/304338","pdf_url":null,"source":{"id":"https://openalex.org/S4306400564","display_name":"PubliCatt (Universit\u00e0 Cattolica del Sacro Cuore)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/s24113383","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s24113383","pdf_url":"https://www.mdpi.com/1424-8220/24/11/3383/pdf?version=1716556017","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1857088242","display_name":null,"funder_award_id":"Mission 4","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G2143504788","display_name":null,"funder_award_id":"3277","funder_id":"https://openalex.org/F4320322510","funder_display_name":"Sapienza Universit\u00e0 di Roma"},{"id":"https://openalex.org/G2381290473","display_name":null,"funder_award_id":"CUP B83C22002820006","funder_id":"https://openalex.org/F4320322510","funder_display_name":"Sapienza Universit\u00e0 di Roma"},{"id":"https://openalex.org/G2974696270","display_name":null,"funder_award_id":"Component 2","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3891025116","display_name":null,"funder_award_id":"RM11916B792AEFF7","funder_id":"https://openalex.org/F4320322510","funder_display_name":"Sapienza Universit\u00e0 di Roma"},{"id":"https://openalex.org/G4258564617","display_name":null,"funder_award_id":"European Union-NextGenerationEU","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4971014005","display_name":null,"funder_award_id":"CUP B83C22002820006","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5019181742","display_name":null,"funder_award_id":"ECS 0000024","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5538284277","display_name":null,"funder_award_id":"National Recovery","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5557213161","display_name":null,"funder_award_id":"00000","funder_id":"https://openalex.org/F4320321781","funder_display_name":"Ministero della Salute"},{"id":"https://openalex.org/G6025850787","display_name":null,"funder_award_id":"B83C22002820006","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8192490647","display_name":null,"funder_award_id":"ECS 0000024","funder_id":"https://openalex.org/F4320322510","funder_display_name":"Sapienza Universit\u00e0 di Roma"},{"id":"https://openalex.org/G8363454223","display_name":null,"funder_award_id":"0000024","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8386731437","display_name":null,"funder_award_id":"Resilience Plan (NRRP)","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321781","display_name":"Ministero della Salute","ror":"https://ror.org/00789fa95"},{"id":"https://openalex.org/F4320322510","display_name":"Sapienza Universit\u00e0 di Roma","ror":"https://ror.org/02be6w209"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4398777260.pdf"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W1578285471","https://openalex.org/W1862989971","https://openalex.org/W1908149944","https://openalex.org/W1965933207","https://openalex.org/W1973089587","https://openalex.org/W1975553175","https://openalex.org/W1995602602","https://openalex.org/W1995962299","https://openalex.org/W1996152000","https://openalex.org/W2004703030","https://openalex.org/W2030637965","https://openalex.org/W2051897265","https://openalex.org/W2054635074","https://openalex.org/W2055111011","https://openalex.org/W2059632775","https://openalex.org/W2080019421","https://openalex.org/W2094210403","https://openalex.org/W2110148884","https://openalex.org/W2127515106","https://openalex.org/W2134208433","https://openalex.org/W2135568518","https://openalex.org/W2159015851","https://openalex.org/W2169969818","https://openalex.org/W2306626597","https://openalex.org/W2507537602","https://openalex.org/W2613108702","https://openalex.org/W2618687596","https://openalex.org/W2737110471","https://openalex.org/W2899106533","https://openalex.org/W2915436778","https://openalex.org/W2918101262","https://openalex.org/W2926726841","https://openalex.org/W2966974311","https://openalex.org/W3006629761","https://openalex.org/W3016907416","https://openalex.org/W3017202750","https://openalex.org/W3025982630","https://openalex.org/W3037547543","https://openalex.org/W3042105201","https://openalex.org/W3045120309","https://openalex.org/W3097198902","https://openalex.org/W3183362593","https://openalex.org/W3183789704","https://openalex.org/W3199669692","https://openalex.org/W3200103728","https://openalex.org/W3204293034","https://openalex.org/W3204647523","https://openalex.org/W4200608463","https://openalex.org/W4206024274","https://openalex.org/W4251314106","https://openalex.org/W4251432945","https://openalex.org/W4285391700","https://openalex.org/W4292873504","https://openalex.org/W4296109034","https://openalex.org/W4297879452","https://openalex.org/W4303628062","https://openalex.org/W6680125967"],"related_works":["https://openalex.org/W4205296404","https://openalex.org/W2320346276","https://openalex.org/W3178656640","https://openalex.org/W2356699866","https://openalex.org/W4241436983","https://openalex.org/W4306641919","https://openalex.org/W2768492030","https://openalex.org/W4323315835","https://openalex.org/W2620289816","https://openalex.org/W2388705147"],"abstract_inverted_index":{"Adherent":[0],"cells":[1,78,200,206],"perceive":[2],"mechanical":[3,32],"feedback":[4,110],"from":[5],"the":[6,26,30,49,59,74,80,100,121,138,159,162,177,186,198,204,209],"underlying":[7],"matrix":[8],"and":[9,52,79,109,130,149,164,180],"convert":[10],"it":[11,133],"into":[12],"biochemical":[13],"signals":[14],"through":[15],"a":[16,41,55,66,173],"process":[17],"known":[18],"as":[19,40],"mechanotransduction.":[20],"The":[21,95,114],"response":[22],"to":[23,136,157],"changes":[24],"in":[25,118,197,201,207],"microenvironment":[27],"relies":[28],"on":[29,90,99,153],"cell\u2019s":[31],"properties,":[33],"including":[34],"elasticity,":[35],"which":[36],"was":[37,86,116,134,195],"recently":[38],"identified":[39],"biomarker":[42],"for":[43,58,111],"various":[44],"diseases.":[45],"Here,":[46],"we":[47],"propose":[48],"design,":[50],"development,":[51],"characterization":[53],"of":[54,61,103,120,125,141,161,176],"new":[56],"system":[57,115],"measurement":[60],"adherent":[62,77],"cells\u2019":[63,70],"strain":[64,122,139,192],"drop,":[65],"parameter":[67],"correlated":[68],"with":[69,88,92,203],"elasticity.":[71],"To":[72],"consider":[73],"interplay":[75],"between":[76],"host":[81],"extracellular":[82,166],"matrix,":[83],"cell":[84,144],"stretching":[85,102],"combined":[87],"adhesion":[89],"substrates":[91,156],"different":[93,155],"stiffnesses.":[94],"technique":[96],"is":[97],"based":[98],"linear":[101],"silicone":[104],"chambers,":[105],"high-speed":[106],"image":[107,112,183],"acquisition,":[108],"centering.":[113,184],"characterized":[117],"terms":[119],"homogeneity,":[123,172],"impact":[124],"collagen":[126,178],"coating,":[127,179],"centering":[128],"capability,":[129],"sensitivity.":[131],"Subsequently,":[132],"employed":[135],"measure":[137],"drop":[140,193],"two":[142,154],"osteosarcoma":[143],"lines,":[145],"low-aggressive":[146],"osteoblast-like":[147],"SaOS-2":[148,205],"high-aggressive":[150],"143B,":[151],"cultured":[152],"recall":[158],"stiffness":[160],"bone":[163],"lung":[165],"matrices.":[167],"Results":[168],"demonstrated":[169],"good":[170],"substrate":[171],"negligible":[174],"effect":[175],"an":[181,190],"accurate":[182],"Finally,":[185],"experimental":[187],"results":[188],"showed":[189],"average":[191],"that":[194],"lower":[196],"143B":[199],"comparison":[202],"all":[208],"tested":[210],"conditions.":[211]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}
