{"id":"https://openalex.org/W4390347125","doi":"https://doi.org/10.3390/s24010186","title":"Development of Liquid-Phase Plasmonic Sensor Platforms for Prospective Biomedical Applications","display_name":"Development of Liquid-Phase Plasmonic Sensor Platforms for Prospective Biomedical Applications","publication_year":2023,"publication_date":"2023-12-28","ids":{"openalex":"https://openalex.org/W4390347125","doi":"https://doi.org/10.3390/s24010186","pmid":"https://pubmed.ncbi.nlm.nih.gov/38203048"},"language":"en","primary_location":{"id":"doi:10.3390/s24010186","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s24010186","pdf_url":"https://www.mdpi.com/1424-8220/24/1/186/pdf?version=1703764637","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/24/1/186/pdf?version=1703764637","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075570513","display_name":"Sezin Say\u0131n","orcid":"https://orcid.org/0000-0003-0662-5338"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sezin Sayin","raw_affiliation_strings":["Department of Electrical and Computer Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA"],"raw_orcid":"https://orcid.org/0000-0003-0662-5338","affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102770233","display_name":"You Zhou","orcid":"https://orcid.org/0000-0001-5999-5696"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"You Zhou","raw_affiliation_strings":["Department of Electrical and Computer Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046544472","display_name":"Sheng Wang","orcid":"https://orcid.org/0000-0002-2051-4426"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sheng Wang","raw_affiliation_strings":["Department of Biomedical Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100581871","display_name":"Andres Acosta Rodriguez","orcid":null},"institutions":[{"id":"https://openalex.org/I875511016","display_name":"ENVIRON (United States)","ror":"https://ror.org/04amahm38","country_code":"US","type":"company","lineage":["https://openalex.org/I875511016"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andres Acosta Rodriguez","raw_affiliation_strings":["3D Enviro, Barboursville, VA 22923, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3D Enviro, Barboursville, VA 22923, USA","institution_ids":["https://openalex.org/I875511016"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016036076","display_name":"Mona Zaghloul","orcid":"https://orcid.org/0000-0003-1089-5138"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mona Zaghloul","raw_affiliation_strings":["Department of Electrical and Computer Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA"],"raw_orcid":"https://orcid.org/0000-0003-1089-5138","affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, School of Engineering and Applied Science, The George Washington University, Washington, DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5075570513"],"corresponding_institution_ids":["https://openalex.org/I193531525"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":0.6218,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.6489511,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"186","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10295","display_name":"Plasmonic and Surface Plasmon Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10295","display_name":"Plasmonic and Surface Plasmon Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.7494890689849854},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.6409556865692139},{"id":"https://openalex.org/keywords/surface-plasmon-resonance","display_name":"Surface plasmon resonance","score":0.6176502108573914},{"id":"https://openalex.org/keywords/fabrication","display_name":"Fabrication","score":0.5737859010696411},{"id":"https://openalex.org/keywords/plasmon","display_name":"Plasmon","score":0.5680650472640991},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5323709845542908},{"id":"https://openalex.org/keywords/refractive-index","display_name":"Refractive index","score":0.5138059258460999},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.4709038734436035},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.13175174593925476}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7494890689849854},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.6409556865692139},{"id":"https://openalex.org/C106847996","wikidata":"https://www.wikidata.org/wiki/Q898756","display_name":"Surface plasmon resonance","level":3,"score":0.6176502108573914},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.5737859010696411},{"id":"https://openalex.org/C110879396","wikidata":"https://www.wikidata.org/wiki/Q58392","display_name":"Plasmon","level":2,"score":0.5680650472640991},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5323709845542908},{"id":"https://openalex.org/C42067758","wikidata":"https://www.wikidata.org/wiki/Q174102","display_name":"Refractive index","level":2,"score":0.5138059258460999},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.4709038734436035},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.13175174593925476},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004583","descriptor_name":"Electrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004583","descriptor_name":"Electrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004583","descriptor_name":"Electrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004583","descriptor_name":"Electrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005898","descriptor_name":"Glass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005898","descriptor_name":"Glass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005898","descriptor_name":"Glass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005898","descriptor_name":"Glass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/s24010186","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s24010186","pdf_url":"https://www.mdpi.com/1424-8220/24/1/186/pdf?version=1703764637","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:38203048","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38203048","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10781335","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10781335","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10781335/pdf/sensors-24-00186.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:d4d716acd2ed49db9d548cc6851afc51","is_oa":true,"landing_page_url":"https://doaj.org/article/d4d716acd2ed49db9d548cc6851afc51","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 24, Iss 1, p 186 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/s24010186","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s24010186","pdf_url":"https://www.mdpi.com/1424-8220/24/1/186/pdf?version=1703764637","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309515","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67"},{"id":"https://openalex.org/F4320332178","display_name":"National Institute of Standards and Technology","ror":"https://ror.org/05xpvk416"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390347125.pdf"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1810193252","https://openalex.org/W2023142235","https://openalex.org/W2034770584","https://openalex.org/W2120686074","https://openalex.org/W2178224149","https://openalex.org/W2484592576","https://openalex.org/W2769014132","https://openalex.org/W2949545283","https://openalex.org/W2991650974","https://openalex.org/W3015500613","https://openalex.org/W3082878832","https://openalex.org/W3162877219","https://openalex.org/W3164489503","https://openalex.org/W3165547818","https://openalex.org/W3182435032","https://openalex.org/W4213239607","https://openalex.org/W4231660377","https://openalex.org/W4285183587","https://openalex.org/W4380995973"],"related_works":["https://openalex.org/W2082914599","https://openalex.org/W3103016203","https://openalex.org/W2756570351","https://openalex.org/W2106238498","https://openalex.org/W2463681241","https://openalex.org/W4200355601","https://openalex.org/W97203997","https://openalex.org/W161520385","https://openalex.org/W2032606118","https://openalex.org/W4388990742"],"abstract_inverted_index":{"Localized":[0],"Surface":[1],"Plasmon":[2],"Resonance":[3],"(LSPR)":[4],"is":[5,107],"an":[6],"optical":[7],"method":[8],"for":[9,45,62,72,91,109],"detecting":[10],"changes":[11],"in":[12,67,77,182],"refractive":[13],"index":[14],"by":[15],"the":[16,52,122,125,161,177],"interaction":[17],"between":[18],"incident":[19],"light":[20],"and":[21,43,143,164,180],"delocalized":[22],"electrons":[23],"within":[24,171],"specific":[25],"metal":[26],"thin":[27],"films'":[28],"localized":[29],"\"hot":[30],"spots\".":[31],"LSPR-based":[32,55],"sensors":[33],"possess":[34],"advantages,":[35],"including":[36],"their":[37],"compact":[38],"size,":[39],"enhanced":[40],"sensitivity,":[41],"cost-effectiveness,":[42],"suitability":[44],"point-of-care":[46],"applications.":[47],"This":[48,158],"research":[49],"focuses":[50],"on":[51],"development":[53],"of":[54,104,124,154,166],"nanohole":[56],"arrays":[57],"(NHAs)":[58],"as":[59],"a":[60,88,100,128,135,139,144,172,183],"platform":[61],"monitoring":[63],"probe/target":[64],"binding":[65],"events":[66],"real":[68],"time":[69],"without":[70],"labeling,":[71],"low-level":[73],"biomolecular":[74],"target":[75,93],"detection":[76],"biomedical":[78],"diagnostics.":[79],"To":[80,120],"achieve":[81],"this":[82,84],"objective,":[83],"study":[85,159],"involves":[86],"creating":[87],"liquid-phase":[89,126,184],"setup":[90],"capturing":[92],"molecules.":[94],"Finite-difference":[95],"time-domain":[96],"simulations":[97],"revealed":[98],"that":[99],"75":[101],"nm":[102],"thickness":[103],"gold":[105],"(Au)":[106],"ideal":[108],"NHA":[110],"structures,":[111],"which":[112],"were":[113],"visually":[114],"examined":[115],"using":[116,134],"scanning":[117],"electron":[118],"microscopy.":[119],"illustrate":[121],"functionality":[123,179],"sensor,":[127],"PDMS":[129,173],"microfluidic":[130,174],"channel":[131],"was":[132],"fabricated":[133],"3D-printed":[136],"mold":[137],"with":[138],"glass":[140,146],"slide":[141],"base":[142],"top":[145],"cover":[147],"slip,":[148],"enabling":[149],"reflectance-mode":[150],"measurements":[151],"from":[152],"each":[153],"four":[155],"device":[156],"sectors.":[157],"shows":[160],"design,":[162],"fabrication,":[163],"assessment":[165],"NHA-based":[167],"LSPR":[168],"sensor":[169],"platforms":[170],"channel,":[175],"confirming":[176],"sensor's":[178],"reproducibility":[181],"environment.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1}],"updated_date":"2026-05-30T09:04:40.226872","created_date":"2025-10-10T00:00:00"}