{"id":"https://openalex.org/W4200104165","doi":"https://doi.org/10.3390/s22010161","title":"Advances in Design Strategies of Multiplex Electrochemical Aptasensors","display_name":"Advances in Design Strategies of Multiplex Electrochemical Aptasensors","publication_year":2021,"publication_date":"2021-12-27","ids":{"openalex":"https://openalex.org/W4200104165","doi":"https://doi.org/10.3390/s22010161","pmid":"https://pubmed.ncbi.nlm.nih.gov/35009703"},"language":"en","primary_location":{"id":"doi:10.3390/s22010161","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s22010161","pdf_url":"https://www.mdpi.com/1424-8220/22/1/161/pdf?version=1640665885","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/22/1/161/pdf?version=1640665885","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067709355","display_name":"Iwona Grabowska","orcid":"https://orcid.org/0000-0002-5056-7828"},"institutions":[{"id":"https://openalex.org/I4210137647","display_name":"InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences","ror":"https://ror.org/04cnktn59","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210137647","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Iwona Grabowska","raw_affiliation_strings":["Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland"],"raw_orcid":"https://orcid.org/0000-0002-5056-7828","affiliations":[{"raw_affiliation_string":"Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland","institution_ids":["https://openalex.org/I4210137647","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019399514","display_name":"Maria Hepel","orcid":"https://orcid.org/0000-0002-8127-8260"},"institutions":[{"id":"https://openalex.org/I83328411","display_name":"State University of New York at Potsdam","ror":"https://ror.org/032qgrc76","country_code":"US","type":"education","lineage":["https://openalex.org/I83328411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Hepel","raw_affiliation_strings":["Department of Chemistry, State University of New York at Potsdam, Potsdam, NY 13676, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, State University of New York at Potsdam, Potsdam, NY 13676, USA","institution_ids":["https://openalex.org/I83328411"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005619041","display_name":"Katarzyna Kurz\u0105tkowska","orcid":"https://orcid.org/0000-0001-8996-3468"},"institutions":[{"id":"https://openalex.org/I4210137647","display_name":"InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences","ror":"https://ror.org/04cnktn59","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210137647","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Katarzyna Kurz\u0105tkowska-Adaszy\u0144ska","raw_affiliation_strings":["Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland"],"raw_orcid":"https://orcid.org/0000-0001-8996-3468","affiliations":[{"raw_affiliation_string":"Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland","institution_ids":["https://openalex.org/I4210137647","https://openalex.org/I99542240"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005619041","https://openalex.org/A5067709355"],"corresponding_institution_ids":["https://openalex.org/I4210137647","https://openalex.org/I99542240"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2673},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2673},"fwci":1.7025,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.85094018,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"22","issue":"1","first_page":"161","last_page":"161"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aptamer","display_name":"Aptamer","score":0.7364016771316528},{"id":"https://openalex.org/keywords/multiplex","display_name":"Multiplex","score":0.6659528017044067},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.6319612264633179},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.572130560874939},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.540201723575592},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.51917564868927},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.4247104525566101},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2482781708240509},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.1995849609375},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.09359043836593628}],"concepts":[{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.7364016771316528},{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.6659528017044067},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6319612264633179},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.572130560874939},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.540201723575592},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.51917564868927},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.4247104525566101},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2482781708240509},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1995849609375},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.09359043836593628},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/s22010161","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s22010161","pdf_url":"https://www.mdpi.com/1424-8220/22/1/161/pdf?version=1640665885","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:35009703","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35009703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:184f6269b3af4e29ac65861ad4c29bd4","is_oa":true,"landing_page_url":"https://doaj.org/article/184f6269b3af4e29ac65861ad4c29bd4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 22, Iss 1, p 161 (2021)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1424-8220/22/1/161/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s22010161","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 22; Issue 1; Pages: 161","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8749765","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8749765","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s22010161","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s22010161","pdf_url":"https://www.mdpi.com/1424-8220/22/1/161/pdf?version=1640665885","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/12","score":0.44999998807907104,"display_name":"Responsible consumption and production"}],"awards":[{"id":"https://openalex.org/G3050043422","display_name":null,"funder_award_id":"2020/37/B/NZ9/03423","funder_id":"https://openalex.org/F4320322511","funder_display_name":"Narodowe Centrum Nauki"}],"funders":[{"id":"https://openalex.org/F4320322511","display_name":"Narodowe Centrum Nauki","ror":"https://ror.org/03ha2q922"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4200104165.pdf"},"referenced_works_count":93,"referenced_works":["https://openalex.org/W866830277","https://openalex.org/W1975860847","https://openalex.org/W1986709785","https://openalex.org/W1989385033","https://openalex.org/W1990096893","https://openalex.org/W1993603706","https://openalex.org/W1997097517","https://openalex.org/W2018608826","https://openalex.org/W2039300520","https://openalex.org/W2042546562","https://openalex.org/W2043369729","https://openalex.org/W2046917042","https://openalex.org/W2069105811","https://openalex.org/W2071449427","https://openalex.org/W2078641188","https://openalex.org/W2079321730","https://openalex.org/W2095421113","https://openalex.org/W2096551653","https://openalex.org/W2100451929","https://openalex.org/W2103186051","https://openalex.org/W2104525153","https://openalex.org/W2127630624","https://openalex.org/W2131359117","https://openalex.org/W2139919009","https://openalex.org/W2141691546","https://openalex.org/W2151470860","https://openalex.org/W2154572268","https://openalex.org/W2160499731","https://openalex.org/W2191688436","https://openalex.org/W2195854070","https://openalex.org/W2222062048","https://openalex.org/W2259198983","https://openalex.org/W2312650522","https://openalex.org/W2334830949","https://openalex.org/W2414421995","https://openalex.org/W2474099094","https://openalex.org/W2521245452","https://openalex.org/W2521833308","https://openalex.org/W2528767583","https://openalex.org/W2577505336","https://openalex.org/W2597620645","https://openalex.org/W2606594182","https://openalex.org/W2608357672","https://openalex.org/W2625950084","https://openalex.org/W2734615474","https://openalex.org/W2737126721","https://openalex.org/W2763769864","https://openalex.org/W2768379816","https://openalex.org/W2797385045","https://openalex.org/W2800712163","https://openalex.org/W2800996381","https://openalex.org/W2801819987","https://openalex.org/W2893551547","https://openalex.org/W2904049032","https://openalex.org/W2904280427","https://openalex.org/W2909041008","https://openalex.org/W2910310334","https://openalex.org/W2946393709","https://openalex.org/W2951563033","https://openalex.org/W2953667108","https://openalex.org/W2966320388","https://openalex.org/W2972523593","https://openalex.org/W2974017606","https://openalex.org/W2979526063","https://openalex.org/W2983228537","https://openalex.org/W2988181042","https://openalex.org/W2989998401","https://openalex.org/W2990971121","https://openalex.org/W2999694041","https://openalex.org/W3006394702","https://openalex.org/W3007631847","https://openalex.org/W3008940014","https://openalex.org/W3008967754","https://openalex.org/W3013074811","https://openalex.org/W3016561121","https://openalex.org/W3017124731","https://openalex.org/W3029634910","https://openalex.org/W3035975148","https://openalex.org/W3038894958","https://openalex.org/W3046277050","https://openalex.org/W3089318953","https://openalex.org/W3092031048","https://openalex.org/W3118752881","https://openalex.org/W3123469883","https://openalex.org/W3124516157","https://openalex.org/W3125032810","https://openalex.org/W3125094216","https://openalex.org/W3135642945","https://openalex.org/W3147436748","https://openalex.org/W3154215416","https://openalex.org/W3156941871","https://openalex.org/W3212529410","https://openalex.org/W4254129269"],"related_works":["https://openalex.org/W2913646003","https://openalex.org/W2033684641","https://openalex.org/W2967136651","https://openalex.org/W2081632393","https://openalex.org/W2147509954","https://openalex.org/W4389944751","https://openalex.org/W1970773045","https://openalex.org/W3092671456","https://openalex.org/W2566736735","https://openalex.org/W2378104911"],"abstract_inverted_index":{"In":[0,127],"recent":[1,187],"years,":[2],"the":[3,17,28,65,89,95,100,104,109,111,167,173,182,204,209],"need":[4],"for":[5,49,121,158],"simple,":[6],"fast,":[7],"and":[8,13,16,85,92,103,132,142,148,198,206,214,218],"economical":[9],"detection":[10,97,123,191],"of":[11,22,30,37,40,88,94,106,124,169,175,189,208],"food":[12,196],"environmental":[14,199],"contaminants,":[15],"necessity":[18],"to":[19,74,116],"monitor":[20],"biomarkers":[21],"different":[23,170],"diseases":[24],"have":[25],"considerably":[26],"accelerated":[27],"development":[29],"biosensor":[31],"technology.":[32],"However,":[33],"designing":[34],"biosensors":[35],"capable":[36],"simultaneous":[38,122],"determination":[39],"two":[41],"or":[42],"more":[43],"analytes":[44],"in":[45,56,172,193],"a":[46,52,61],"single":[47,53,57,75],"measurement,":[48],"example":[50],"on":[51,99,108,137,154,179],"working":[54],"electrode":[55],"solution,":[58],"is":[59],"still":[60],"great":[62],"challenge.":[63],"On":[64],"other":[66],"hand,":[67],"such":[68,78],"analysis":[69],"offers":[70],"many":[71],"advantages":[72,205],"compared":[73],"analyte":[76],"tests,":[77],"as":[79],"cost":[80],"per":[81],"test,":[82],"labor,":[83],"throughput,":[84],"convenience.":[86],"Because":[87],"high":[90],"sensitivity":[91],"scalability":[93],"electrochemical":[96,112,162],"systems":[98],"one":[101],"hand":[102],"specificity":[105],"aptamers":[107],"other,":[110],"aptasensors":[113,210],"are":[114],"considered":[115],"be":[117],"highly":[118],"effective":[119],"devices":[120],"multiple-target":[125],"analytes.":[126],"this":[128],"review,":[129],"we":[130,165,185,202],"describe":[131],"evaluate":[133],"multi-label":[134],"approaches":[135],"based":[136],"(1)":[138],"metal":[139,143],"quantum":[140],"dots":[141],"ions,":[144],"(2)":[145],"redox":[146],"labels,":[147],"(3)":[149],"enzyme":[150],"labels.":[151],"We":[152],"focus":[153],"recently":[155],"developed":[156,211],"strategies":[157],"multiplex":[159],"sensing":[160],"using":[161],"aptasensors.":[163,177],"Furthermore,":[164],"emphasize":[166],"use":[168],"nanomaterials":[171],"construction":[174],"these":[176],"Based":[178],"examples":[180],"from":[181],"existing":[183],"literature,":[184],"highlight":[186],"applications":[188],"multiplexed":[190],"platforms":[192],"clinical":[194],"diagnostics,":[195],"control,":[197],"monitoring.":[200],"Finally,":[201],"discuss":[203],"disadvantages":[207],"so":[212],"far,":[213],"debate":[215],"possible":[216],"challenges":[217],"prospects.":[219]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":3}],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2025-10-10T00:00:00"}