{"id":"https://openalex.org/W3210383063","doi":"https://doi.org/10.3390/s21217109","title":"Recent Advances on Functional Nucleic-Acid Biosensors","display_name":"Recent Advances on Functional Nucleic-Acid Biosensors","publication_year":2021,"publication_date":"2021-10-26","ids":{"openalex":"https://openalex.org/W3210383063","doi":"https://doi.org/10.3390/s21217109","mag":"3210383063","pmid":"https://pubmed.ncbi.nlm.nih.gov/34770415"},"language":"en","primary_location":{"id":"doi:10.3390/s21217109","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21217109","pdf_url":"https://www.mdpi.com/1424-8220/21/21/7109/pdf?version=1635430321","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/21/21/7109/pdf?version=1635430321","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037623074","display_name":"Xinhong Yu","orcid":"https://orcid.org/0000-0003-0193-3702"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhong Yu","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100362566","display_name":"Shiqi Zhang","orcid":"https://orcid.org/0000-0001-9751-7652"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiqi Zhang","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038537408","display_name":"Wenqiang Guo","orcid":"https://orcid.org/0009-0003-4846-7611"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenqiang Guo","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091375442","display_name":"Boxi Li","orcid":"https://orcid.org/0000-0002-2733-7186"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Boxi Li","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100397455","display_name":"Yang Yang","orcid":"https://orcid.org/0000-0001-8833-7641"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Yang","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022846227","display_name":"Bingqing Xie","orcid":"https://orcid.org/0000-0001-9246-9321"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bingqing Xie","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100343509","display_name":"Ke Li","orcid":"https://orcid.org/0000-0002-7318-1186"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ke Li","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100425463","display_name":"Li Zhang","orcid":"https://orcid.org/0000-0001-8718-0216"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li Zhang","raw_affiliation_strings":["Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"],"raw_orcid":"https://orcid.org/0000-0001-8718-0216","affiliations":[{"raw_affiliation_string":"Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China","institution_ids":["https://openalex.org/I204823248"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5100425463"],"corresponding_institution_ids":["https://openalex.org/I204823248"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":1.71,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.85007095,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"21","issue":"21","first_page":"7109","last_page":"7109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.7887446880340576},{"id":"https://openalex.org/keywords/nucleic-acid","display_name":"Nucleic acid","score":0.7815649509429932},{"id":"https://openalex.org/keywords/nucleic-acid-detection","display_name":"Nucleic acid detection","score":0.5923269391059875},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5320879817008972},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.486347496509552},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.4637758135795593},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.38395729660987854},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2690541446208954},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.17840826511383057},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.117664635181427},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.10138347744941711}],"concepts":[{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.7887446880340576},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.7815649509429932},{"id":"https://openalex.org/C2910367586","wikidata":"https://www.wikidata.org/wiki/Q348667","display_name":"Nucleic acid detection","level":3,"score":0.5923269391059875},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5320879817008972},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.486347496509552},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.4637758135795593},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38395729660987854},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2690541446208954},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.17840826511383057},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.117664635181427},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10138347744941711}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.3390/s21217109","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21217109","pdf_url":"https://www.mdpi.com/1424-8220/21/21/7109/pdf?version=1635430321","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:34770415","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34770415","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:ae90c096478248a19dc97d5cac5c646d","is_oa":true,"landing_page_url":"https://doaj.org/article/ae90c096478248a19dc97d5cac5c646d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 21, Iss 21, p 7109 (2021)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1424-8220/21/21/7109/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s21217109","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 21; Issue 21; Pages: 7109","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8587875","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8587875","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s21217109","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21217109","pdf_url":"https://www.mdpi.com/1424-8220/21/21/7109/pdf?version=1635430321","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","score":0.4699999988079071,"id":"https://metadata.un.org/sdg/17"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3210383063.pdf","grobid_xml":"https://content.openalex.org/works/W3210383063.grobid-xml"},"referenced_works_count":181,"referenced_works":["https://openalex.org/W74748061","https://openalex.org/W106295861","https://openalex.org/W1607004775","https://openalex.org/W1664052481","https://openalex.org/W1706705711","https://openalex.org/W1971242047","https://openalex.org/W1973939499","https://openalex.org/W1979073863","https://openalex.org/W1987024877","https://openalex.org/W1987565198","https://openalex.org/W1991240016","https://openalex.org/W1996419255","https://openalex.org/W2026370504","https://openalex.org/W2029376019","https://openalex.org/W2032462421","https://openalex.org/W2036821913","https://openalex.org/W2038121135","https://openalex.org/W2040498942","https://openalex.org/W2041002283","https://openalex.org/W2046642536","https://openalex.org/W2048780993","https://openalex.org/W2051003686","https://openalex.org/W2052076921","https://openalex.org/W2052678132","https://openalex.org/W2056340969","https://openalex.org/W2056421966","https://openalex.org/W2056594839","https://openalex.org/W2058258413","https://openalex.org/W2059843731","https://openalex.org/W2072867698","https://openalex.org/W2074060742","https://openalex.org/W2074394238","https://openalex.org/W2077008254","https://openalex.org/W2078431154","https://openalex.org/W2079321730","https://openalex.org/W2082259883","https://openalex.org/W2083733102","https://openalex.org/W2084810886","https://openalex.org/W2088495447","https://openalex.org/W2089752526","https://openalex.org/W2093269115","https://openalex.org/W2099958243","https://openalex.org/W2105007932","https://openalex.org/W2114468387","https://openalex.org/W2119262581","https://openalex.org/W2135573504","https://openalex.org/W2136693699","https://openalex.org/W2145848541","https://openalex.org/W2146347293","https://openalex.org/W2146426819","https://openalex.org/W2147934643","https://openalex.org/W2148272663","https://openalex.org/W2154321074","https://openalex.org/W2154572268","https://openalex.org/W2155367951","https://openalex.org/W2160611425","https://openalex.org/W2164154746","https://openalex.org/W2165047663","https://openalex.org/W2187626804","https://openalex.org/W2189574494","https://openalex.org/W2208632078","https://openalex.org/W2239850325","https://openalex.org/W2274832362","https://openalex.org/W2299532471","https://openalex.org/W2315173542","https://openalex.org/W2323748430","https://openalex.org/W2329360889","https://openalex.org/W2331775465","https://openalex.org/W2346053509","https://openalex.org/W2402615551","https://openalex.org/W2405988445","https://openalex.org/W2413713901","https://openalex.org/W2440056850","https://openalex.org/W2462432763","https://openalex.org/W2491085471","https://openalex.org/W2516914000","https://openalex.org/W2520677173","https://openalex.org/W2532041935","https://openalex.org/W2543533284","https://openalex.org/W2554557540","https://openalex.org/W2559100163","https://openalex.org/W2559679950","https://openalex.org/W2560469110","https://openalex.org/W2577709858","https://openalex.org/W2587792769","https://openalex.org/W2593326131","https://openalex.org/W2594627623","https://openalex.org/W2595362216","https://openalex.org/W2606431818","https://openalex.org/W2610672606","https://openalex.org/W2612365971","https://openalex.org/W2618983564","https://openalex.org/W2726959101","https://openalex.org/W2740826651","https://openalex.org/W2743726099","https://openalex.org/W2744074964","https://openalex.org/W2746831066","https://openalex.org/W2754592050","https://openalex.org/W2756779093","https://openalex.org/W2762945473","https://openalex.org/W2769286195","https://openalex.org/W2769320297","https://openalex.org/W2770269437","https://openalex.org/W2770491016","https://openalex.org/W2772288896","https://openalex.org/W2782104880","https://openalex.org/W2789122675","https://openalex.org/W2793621672","https://openalex.org/W2794016977","https://openalex.org/W2802258189","https://openalex.org/W2806777474","https://openalex.org/W2809382883","https://openalex.org/W2860229439","https://openalex.org/W2895036409","https://openalex.org/W2897626234","https://openalex.org/W2899221506","https://openalex.org/W2900783795","https://openalex.org/W2901635167","https://openalex.org/W2901864029","https://openalex.org/W2925187670","https://openalex.org/W2942521757","https://openalex.org/W2946572145","https://openalex.org/W2948241779","https://openalex.org/W2950603264","https://openalex.org/W2965446717","https://openalex.org/W2974158604","https://openalex.org/W2982654239","https://openalex.org/W2986748392","https://openalex.org/W2987312751","https://openalex.org/W2989374861","https://openalex.org/W2990273632","https://openalex.org/W2991992810","https://openalex.org/W2995194981","https://openalex.org/W2995978371","https://openalex.org/W2998780480","https://openalex.org/W2999747699","https://openalex.org/W3003351677","https://openalex.org/W3006260731","https://openalex.org/W3008825089","https://openalex.org/W3010404991","https://openalex.org/W3013079860","https://openalex.org/W3025508668","https://openalex.org/W3037396009","https://openalex.org/W3045370740","https://openalex.org/W3048846415","https://openalex.org/W3080158467","https://openalex.org/W3080866437","https://openalex.org/W3081805669","https://openalex.org/W3085348446","https://openalex.org/W3086971425","https://openalex.org/W3092770920","https://openalex.org/W3095194923","https://openalex.org/W3095915182","https://openalex.org/W3108115150","https://openalex.org/W3114835926","https://openalex.org/W3118182682","https://openalex.org/W3118287645","https://openalex.org/W3120204633","https://openalex.org/W3124323031","https://openalex.org/W3128001346","https://openalex.org/W3128646645","https://openalex.org/W3147698811","https://openalex.org/W3151504910","https://openalex.org/W3156009450","https://openalex.org/W3156642165","https://openalex.org/W3162635440","https://openalex.org/W3165784990","https://openalex.org/W3167751787","https://openalex.org/W3169474474","https://openalex.org/W3173525947","https://openalex.org/W3175790634","https://openalex.org/W3178257603","https://openalex.org/W3182119377","https://openalex.org/W3183323920","https://openalex.org/W3185846652","https://openalex.org/W3190137513","https://openalex.org/W3197111322","https://openalex.org/W4230373848","https://openalex.org/W4232849089","https://openalex.org/W4400840471","https://openalex.org/W6725797640"],"related_works":["https://openalex.org/W2272547605","https://openalex.org/W3031503986","https://openalex.org/W36135598","https://openalex.org/W2417216550","https://openalex.org/W3131875014","https://openalex.org/W1543504406","https://openalex.org/W2322221118","https://openalex.org/W4210872575","https://openalex.org/W2899696050","https://openalex.org/W2562142047"],"abstract_inverted_index":{"In":[0,73,93],"the":[1,11,26,46,95,103,109,121],"past":[2],"few":[3,60],"decades,":[4],"biosensors":[5,23,82],"have":[6,24,50],"been":[7],"gradually":[8],"developed":[9],"for":[10],"rapid":[12],"detection":[13],"and":[14,40,64,71,112,120,125],"monitoring":[15],"of":[16,28,34,54,81,97,99,102,115,128],"human":[17],"diseases.":[18],"Recently,":[19],"functional":[20,79,85,129],"nucleic-acid":[21],"(FNA)":[22],"attracted":[25],"attention":[27],"scholars":[29],"due":[30],"to":[31],"a":[32],"series":[33],"advantages":[35],"such":[36],"as":[37,43,45],"high":[38],"stability":[39],"strong":[41],"specificity,":[42],"well":[44],"significant":[47],"progress":[48],"they":[49],"made":[51],"in":[52],"terms":[53],"biomedical":[55],"applications.":[56],"However,":[57],"there":[58],"are":[59,106,118,133],"reports":[61],"that":[62,83],"systematically":[63],"comprehensively":[65],"summarize":[66],"its":[67],"working":[68],"principles,":[69],"classification":[70],"application.":[72],"this":[74],"review,":[75],"we":[76],"primarily":[77],"introduce":[78],"modes":[80],"combine":[84],"nucleic":[86,130],"acids":[87],"with":[88],"different":[89],"signal":[90],"output":[91],"modes.":[92],"addition,":[94],"mechanisms":[96],"action":[98],"several":[100],"media":[101],"FNA":[104,116],"biosensor":[105],"introduced.":[107],"Finally,":[108],"practical":[110],"application":[111,126],"existing":[113],"problems":[114],"sensors":[117,132],"discussed,":[119],"future":[122],"development":[123],"directions":[124],"prospects":[127],"acid":[131],"prospected.":[134]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}