{"id":"https://openalex.org/W3195731076","doi":"https://doi.org/10.3390/s21165607","title":"In Vitro Electrochemical Detection of Hydrogen Peroxide in Activated Macrophages via a Platinum Microelectrode Array","display_name":"In Vitro Electrochemical Detection of Hydrogen Peroxide in Activated Macrophages via a Platinum Microelectrode Array","publication_year":2021,"publication_date":"2021-08-20","ids":{"openalex":"https://openalex.org/W3195731076","doi":"https://doi.org/10.3390/s21165607","mag":"3195731076","pmid":"https://pubmed.ncbi.nlm.nih.gov/34451050"},"language":"en","primary_location":{"id":"doi:10.3390/s21165607","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21165607","pdf_url":"https://www.mdpi.com/1424-8220/21/16/5607/pdf?version=1629793309","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/21/16/5607/pdf?version=1629793309","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005308504","display_name":"Victor M. Carriere","orcid":null},"institutions":[{"id":"https://openalex.org/I919208787","display_name":"Louisiana Tech University","ror":"https://ror.org/04q9esz89","country_code":"US","type":"education","lineage":["https://openalex.org/I2799628689","https://openalex.org/I919208787"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victor M. Carriere","raw_affiliation_strings":["Biomedical Engineering Department, Louisiana Tech University, Ruston, LA 71272, USA","College of Engineering and Science-Chemistry, Louisiana Tech University, Ruston, LA 71272, USA"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Louisiana Tech University, Ruston, LA 71272, USA","institution_ids":["https://openalex.org/I919208787"]},{"raw_affiliation_string":"College of Engineering and Science-Chemistry, Louisiana Tech University, Ruston, LA 71272, USA","institution_ids":["https://openalex.org/I919208787"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059264838","display_name":"Jolin P. Rodrigues","orcid":null},"institutions":[{"id":"https://openalex.org/I919208787","display_name":"Louisiana Tech University","ror":"https://ror.org/04q9esz89","country_code":"US","type":"education","lineage":["https://openalex.org/I2799628689","https://openalex.org/I919208787"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jolin P. Rodrigues","raw_affiliation_strings":["Biomedical Engineering Department, Louisiana Tech University, Ruston, LA 71272, USA","College of Engineering and Science-Chemistry, Louisiana Tech University, Ruston, LA 71272, USA"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Louisiana Tech University, Ruston, LA 71272, USA","institution_ids":["https://openalex.org/I919208787"]},{"raw_affiliation_string":"College of Engineering and Science-Chemistry, Louisiana Tech University, Ruston, LA 71272, USA","institution_ids":["https://openalex.org/I919208787"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070237355","display_name":"Chao Tan","orcid":"https://orcid.org/0000-0002-6369-3380"},"institutions":[{"id":"https://openalex.org/I919208787","display_name":"Louisiana Tech University","ror":"https://ror.org/04q9esz89","country_code":"US","type":"education","lineage":["https://openalex.org/I2799628689","https://openalex.org/I919208787"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chao Tan","raw_affiliation_strings":["Institute for Micromanufacturing, Louisiana Tech University, Ruston, LA 71272, USA"],"affiliations":[{"raw_affiliation_string":"Institute for Micromanufacturing, Louisiana Tech University, Ruston, LA 71272, USA","institution_ids":["https://openalex.org/I919208787"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082428844","display_name":"Prabhu U. Arumugam","orcid":"https://orcid.org/0000-0001-9942-7036"},"institutions":[{"id":"https://openalex.org/I919208787","display_name":"Louisiana Tech University","ror":"https://ror.org/04q9esz89","country_code":"US","type":"education","lineage":["https://openalex.org/I2799628689","https://openalex.org/I919208787"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prabhu Arumugam","raw_affiliation_strings":["Institute for Micromanufacturing, Louisiana Tech University, Ruston, LA 71272, USA"],"affiliations":[{"raw_affiliation_string":"Institute for Micromanufacturing, Louisiana Tech University, Ruston, LA 71272, USA","institution_ids":["https://openalex.org/I919208787"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007047788","display_name":"Scott Poh","orcid":"https://orcid.org/0000-0002-3544-6446"},"institutions":[{"id":"https://openalex.org/I919208787","display_name":"Louisiana Tech University","ror":"https://ror.org/04q9esz89","country_code":"US","type":"education","lineage":["https://openalex.org/I2799628689","https://openalex.org/I919208787"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scott Poh","raw_affiliation_strings":["College of Engineering and Science-Chemistry, Louisiana Tech University, Ruston, LA 71272, USA"],"affiliations":[{"raw_affiliation_string":"College of Engineering and Science-Chemistry, Louisiana Tech University, Ruston, LA 71272, USA","institution_ids":["https://openalex.org/I919208787"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5007047788"],"corresponding_institution_ids":["https://openalex.org/I919208787"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":1.1131,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.77415414,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"21","issue":"16","first_page":"5607","last_page":"5607"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"Reactive oxygen species","score":0.7123349905014038},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"Oxidative stress","score":0.6554870009422302},{"id":"https://openalex.org/keywords/hydrogen-peroxide","display_name":"Hydrogen peroxide","score":0.631563663482666},{"id":"https://openalex.org/keywords/inflammation","display_name":"Inflammation","score":0.6246464252471924},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.620224118232727},{"id":"https://openalex.org/keywords/superoxide","display_name":"Superoxide","score":0.491164892911911},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"Lipopolysaccharide","score":0.4343731999397278},{"id":"https://openalex.org/keywords/extracellular","display_name":"Extracellular","score":0.4171217083930969},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.3627597391605377},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.36138588190078735},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.27221381664276123},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2105867862701416},{"id":"https://openalex.org/keywords/enzyme","display_name":"Enzyme","score":0.15794172883033752}],"concepts":[{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.7123349905014038},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.6554870009422302},{"id":"https://openalex.org/C533411734","wikidata":"https://www.wikidata.org/wiki/Q171877","display_name":"Hydrogen peroxide","level":2,"score":0.631563663482666},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6246464252471924},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.620224118232727},{"id":"https://openalex.org/C2780795997","wikidata":"https://www.wikidata.org/wiki/Q413283","display_name":"Superoxide","level":3,"score":0.491164892911911},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.4343731999397278},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.4171217083930969},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3627597391605377},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.36138588190078735},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27221381664276123},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2105867862701416},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.15794172883033752}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010984","descriptor_name":"Platinum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010984","descriptor_name":"Platinum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010984","descriptor_name":"Platinum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/s21165607","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21165607","pdf_url":"https://www.mdpi.com/1424-8220/21/16/5607/pdf?version=1629793309","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:34451050","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34451050","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:7e43798b7c194defa1aafcedf7df45a1","is_oa":true,"landing_page_url":"https://doaj.org/article/7e43798b7c194defa1aafcedf7df45a1","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 21, Iss 16, p 5607 (2021)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1424-8220/21/16/5607/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s21165607","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 21; Issue 16; Pages: 5607","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8402354","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8402354","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s21165607","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21165607","pdf_url":"https://www.mdpi.com/1424-8220/21/16/5607/pdf?version=1629793309","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3195731076.pdf","grobid_xml":"https://content.openalex.org/works/W3195731076.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W114440940","https://openalex.org/W852335522","https://openalex.org/W1974997758","https://openalex.org/W1978157745","https://openalex.org/W1991952977","https://openalex.org/W1997684038","https://openalex.org/W2007636933","https://openalex.org/W2013654923","https://openalex.org/W2023875464","https://openalex.org/W2025082986","https://openalex.org/W2031084334","https://openalex.org/W2049853415","https://openalex.org/W2051906209","https://openalex.org/W2053148789","https://openalex.org/W2066411725","https://openalex.org/W2070855360","https://openalex.org/W2104901632","https://openalex.org/W2108409617","https://openalex.org/W2112175677","https://openalex.org/W2134798397","https://openalex.org/W2165985796","https://openalex.org/W2172680325","https://openalex.org/W2319967189","https://openalex.org/W2338506659","https://openalex.org/W2568510753","https://openalex.org/W2571996518","https://openalex.org/W2867620004","https://openalex.org/W2901969888","https://openalex.org/W2958386701","https://openalex.org/W3003917458","https://openalex.org/W4248078302","https://openalex.org/W6644794840","https://openalex.org/W6675913783"],"related_works":["https://openalex.org/W2147934559","https://openalex.org/W2051208451","https://openalex.org/W2037157726","https://openalex.org/W2072710081","https://openalex.org/W2403625851","https://openalex.org/W2062709989","https://openalex.org/W2025098696","https://openalex.org/W2056261036","https://openalex.org/W1508785783","https://openalex.org/W2019421902"],"abstract_inverted_index":{"Oxidative":[0],"stress,":[1],"an":[2],"excess":[3],"of":[4,42,53,58,71,81,124,141,151,188,197],"endogenous":[5],"or":[6],"exogenous":[7],"reactive":[8],"oxygen":[9],"species":[10,44],"(ROS)":[11],"in":[12,36,55,96,176,205],"the":[13,50,79,122,148,161,173,186],"human":[14],"body,":[15],"is":[16,74],"closely":[17],"aligned":[18],"with":[19,180,199],"inflammatory":[20],"responses.":[21],"ROS":[22],"such":[23],"as":[24,191],"hydrogen":[25],"peroxide":[26],"(H<sub>2</sub>O<sub>2</sub>),":[27],"superoxide,":[28],"and":[29,63,93],"radical":[30],"hydroxyl":[31],"ions":[32],"serve":[33],"essential":[34],"functions":[35],"fighting":[37],"infection;":[38],"however,":[39],"chronic":[40],"elevation":[41],"these":[43,105],"irreversibly":[45],"damages":[46],"cellular":[47],"components.":[48],"Given":[49],"central":[51],"role":[52],"inflammation":[54],"a":[56,66,82,154,192,200],"variety":[57],"diseases,":[59],"including":[60],"Alzheimer's":[61],"disease":[62],"rheumatoid":[64],"arthritis,":[65],"low-cost,":[67],"extracellular,":[68],"non-invasive":[69],"assay":[70],"H<sub>2</sub>O<sub>2</sub>":[72,97,125,166],"measurement":[73],"needed.":[75],"This":[76],"work":[77],"reports":[78],"use":[80,187],"platinum":[83],"microelectrode":[84],"array":[85],"(Pt":[86],"MEA)-based":[87],"ceramic":[88],"probe":[89,162,190],"to":[90,112,120,134],"detect":[91,121],"time-":[92],"concentration-dependent":[94],"variations":[95],"production":[98,167],"by":[99,109,127,168],"activated":[100,108],"RAW":[101],"264.7":[102],"macrophages.":[103],"First,":[104],"cells":[106,128,178],"were":[107],"lipopolysaccharide":[110],"(LPS)":[111],"induce":[113],"oxidative":[114],"stress.":[115],"Chronoamperometry":[116],"was":[117,143],"then":[118],"employed":[119],"quantity":[123],"released":[126],"at":[129],"various":[130],"time":[131],"intervals":[132],"up":[133],"48":[135],"h.":[136],"The":[137],"most":[138],"stimulatory":[139],"concentration":[140],"LPS":[142],"identified.":[144],"Further":[145],"experiments":[146],"assessed":[147],"anti-inflammatory":[149],"effect":[150,175],"dexamethasone":[152],"(Dex),":[153],"commonly":[155],"prescribed":[156],"steroid":[157],"medication.":[158],"As":[159],"expected,":[160],"detected":[163],"significantly":[164],"increased":[165],"LPS-doped":[169,177],"macrophages,":[170],"subsequently":[171],"diminishing":[172],"pro-inflammatory":[174],"treated":[179],"Dex.":[181],"These":[182],"results":[183],"strongly":[184],"support":[185],"this":[189],"non-invasive,":[193],"robust,":[194],"point-of-care":[195],"test":[196],"inflammation,":[198],"high":[201],"potential":[202],"for":[203],"multiplexing":[204],"further":[206],"studies.":[207]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}