{"id":"https://openalex.org/W3162084616","doi":"https://doi.org/10.3390/s21103358","title":"Recent Advancements in Enzyme-Based Lateral Flow Immunoassays","display_name":"Recent Advancements in Enzyme-Based Lateral Flow Immunoassays","publication_year":2021,"publication_date":"2021-05-12","ids":{"openalex":"https://openalex.org/W3162084616","doi":"https://doi.org/10.3390/s21103358","mag":"3162084616","pmid":"https://pubmed.ncbi.nlm.nih.gov/34065971"},"language":"en","primary_location":{"id":"doi:10.3390/s21103358","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21103358","pdf_url":"https://www.mdpi.com/1424-8220/21/10/3358/pdf?version=1620812463","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/21/10/3358/pdf?version=1620812463","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053747856","display_name":"Donato Calabria","orcid":"https://orcid.org/0000-0002-8215-9458"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Donato Calabria","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":"https://orcid.org/0000-0002-8215-9458","affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021150245","display_name":"Maria Maddalena Calabretta","orcid":"https://orcid.org/0000-0002-5673-3073"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Maddalena Calabretta","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":"https://orcid.org/0000-0002-5673-3073","affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049469105","display_name":"Martina Zangheri","orcid":"https://orcid.org/0000-0003-4747-1283"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Martina Zangheri","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052035279","display_name":"Elisa Marchegiani","orcid":null},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisa Marchegiani","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059865020","display_name":"Ilaria Trozzi","orcid":null},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Trozzi","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033162914","display_name":"Massimo Guardigli","orcid":"https://orcid.org/0000-0003-1434-4085"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Guardigli","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067068922","display_name":"Elisa Michelini","orcid":"https://orcid.org/0000-0002-8651-0575"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisa Michelini","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":"https://orcid.org/0000-0002-8651-0575","affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044103198","display_name":"Fabio Di Nardo","orcid":"https://orcid.org/0000-0003-0497-4251"},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabio Di Nardo","raw_affiliation_strings":["Department of Chemistry, University of Turin, Via P. Giuria 5, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0003-0497-4251","affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Turin, Via P. Giuria 5, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082760851","display_name":"Laura Anfossi","orcid":"https://orcid.org/0000-0002-2920-0140"},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Anfossi","raw_affiliation_strings":["Department of Chemistry, University of Turin, Via P. Giuria 5, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0002-2920-0140","affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Turin, Via P. Giuria 5, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076139411","display_name":"Claudio Baggiani","orcid":"https://orcid.org/0000-0003-1024-2532"},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudio Baggiani","raw_affiliation_strings":["Department of Chemistry, University of Turin, Via P. Giuria 5, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0003-1024-2532","affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Turin, Via P. Giuria 5, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000028774","display_name":"Mara Mirasoli","orcid":"https://orcid.org/0000-0001-6553-5039"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Mara Mirasoli","raw_affiliation_strings":["Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Chemistry \"Giacomo Ciamician\", Alma Mater Studiorum-University of Bologna, Via Selmi 2, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5000028774"],"corresponding_institution_ids":["https://openalex.org/I9360294"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":5.0091,"has_fulltext":true,"cited_by_count":83,"citation_normalized_percentile":{"value":0.9628629,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"21","issue":"10","first_page":"3358","last_page":"3358"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12302","display_name":"Advanced Nanomaterials in Catalysis","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6716859340667725},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3871808648109436},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.3734060227870941},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3691345155239105},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.13821110129356384},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.10590803623199463}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6716859340667725},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3871808648109436},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3734060227870941},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3691345155239105},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.13821110129356384},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.10590803623199463}],"mesh":[{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.3390/s21103358","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21103358","pdf_url":"https://www.mdpi.com/1424-8220/21/10/3358/pdf?version=1620812463","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:34065971","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34065971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:iris.unito.it:2318/1788751","is_oa":true,"landing_page_url":"http://hdl.handle.net/2318/1788751","pdf_url":"http://hdl.handle.net/2318/1788751","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:cris.unibo.it:11585/833119","is_oa":true,"landing_page_url":"https://hdl.handle.net/11585/833119","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:9974771b60de4ba39963e21bac179882","is_oa":true,"landing_page_url":"https://doaj.org/article/9974771b60de4ba39963e21bac179882","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 21, Iss 10, p 3358 (2021)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1424-8220/21/10/3358/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s21103358","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 21; Issue 10; Pages: 3358","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8150770","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8150770","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s21103358","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21103358","pdf_url":"https://www.mdpi.com/1424-8220/21/10/3358/pdf?version=1620812463","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4099999964237213,"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9"}],"awards":[{"id":"https://openalex.org/G7578558541","display_name":null,"funder_award_id":"2017YER72K","funder_id":"https://openalex.org/F4320321873","funder_display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca"}],"funders":[{"id":"https://openalex.org/F4320321873","display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","ror":"https://ror.org/0166hxq48"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3162084616.pdf","grobid_xml":"https://content.openalex.org/works/W3162084616.grobid-xml"},"referenced_works_count":99,"referenced_works":["https://openalex.org/W338663261","https://openalex.org/W1843313085","https://openalex.org/W1963803087","https://openalex.org/W1966172361","https://openalex.org/W1969573814","https://openalex.org/W1970801243","https://openalex.org/W1974673121","https://openalex.org/W1976571342","https://openalex.org/W1976652877","https://openalex.org/W1990837884","https://openalex.org/W1994756551","https://openalex.org/W2006648444","https://openalex.org/W2014340379","https://openalex.org/W2023337411","https://openalex.org/W2023584807","https://openalex.org/W2033478996","https://openalex.org/W2035590321","https://openalex.org/W2039888302","https://openalex.org/W2051673992","https://openalex.org/W2061410214","https://openalex.org/W2070572091","https://openalex.org/W2080173526","https://openalex.org/W2085752810","https://openalex.org/W2096461277","https://openalex.org/W2101873913","https://openalex.org/W2107190439","https://openalex.org/W2148855400","https://openalex.org/W2159861516","https://openalex.org/W2161029238","https://openalex.org/W2171695381","https://openalex.org/W2175909925","https://openalex.org/W2205456549","https://openalex.org/W2301534611","https://openalex.org/W2315138333","https://openalex.org/W2329556521","https://openalex.org/W2438068507","https://openalex.org/W2439064925","https://openalex.org/W2465914376","https://openalex.org/W2528721849","https://openalex.org/W2532430498","https://openalex.org/W2565273737","https://openalex.org/W2568632337","https://openalex.org/W2592120073","https://openalex.org/W2605602988","https://openalex.org/W2750224611","https://openalex.org/W2751146173","https://openalex.org/W2754287433","https://openalex.org/W2756185868","https://openalex.org/W2773369511","https://openalex.org/W2773898323","https://openalex.org/W2776358573","https://openalex.org/W2781979611","https://openalex.org/W2791743752","https://openalex.org/W2791746297","https://openalex.org/W2792574019","https://openalex.org/W2794963961","https://openalex.org/W2797886848","https://openalex.org/W2802457709","https://openalex.org/W2803847684","https://openalex.org/W2807191970","https://openalex.org/W2807959326","https://openalex.org/W2809357732","https://openalex.org/W2809868937","https://openalex.org/W2821586886","https://openalex.org/W2883822089","https://openalex.org/W2884806458","https://openalex.org/W2890412537","https://openalex.org/W2890643956","https://openalex.org/W2896041612","https://openalex.org/W2897781899","https://openalex.org/W2901840731","https://openalex.org/W2902039360","https://openalex.org/W2905892447","https://openalex.org/W2906386256","https://openalex.org/W2911363075","https://openalex.org/W2923836007","https://openalex.org/W2945738412","https://openalex.org/W2946869559","https://openalex.org/W2950578523","https://openalex.org/W2954569873","https://openalex.org/W2957813057","https://openalex.org/W2990850433","https://openalex.org/W2991466397","https://openalex.org/W2996234395","https://openalex.org/W3000338635","https://openalex.org/W3005894881","https://openalex.org/W3005956538","https://openalex.org/W3006481147","https://openalex.org/W3008650409","https://openalex.org/W3014124124","https://openalex.org/W3023728379","https://openalex.org/W3033071977","https://openalex.org/W3034980598","https://openalex.org/W3037274684","https://openalex.org/W3085119172","https://openalex.org/W3092484191","https://openalex.org/W3095920756","https://openalex.org/W4210970969","https://openalex.org/W4249218779"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Paper-based":[0],"lateral-flow":[1],"immunoassays":[2],"(LFIAs)":[3],"have":[4,70,166],"achieved":[5],"considerable":[6],"commercial":[7],"success":[8],"and":[9,90,112,148,153,175,213,222],"their":[10],"impact":[11],"in":[12,30,44,72,170,181,198],"diagnostics":[13],"is":[14,63,144],"continuously":[15],"growing.":[16],"LFIA":[17,62,104,124,162,201],"results":[18],"are":[19,224],"often":[20],"obtained":[21],"by":[22,24,106],"visualizing":[23],"the":[25,38,41,45,51,73,80,103,123,132,139,195,205,216],"naked":[26],"eye":[27],"color":[28],"changes":[29],"given":[31],"areas,":[32],"providing":[33],"a":[34,110,157,191],"qualitative":[35],"information":[36],"about":[37],"presence/absence":[39],"of":[40,82,141,194,207,215],"target":[42],"analyte":[43],"sample.":[46],"However,":[47],"this":[48,137,182,185],"platform":[49,105],"has":[50],"potential":[52],"to":[53,79,102,109,189],"provide":[54,190],"ultrasensitive":[55,128],"quantitative":[56,129],"analysis":[57,152],"for":[58,120,135,150,160,177],"several":[59],"applications.":[60],"Indeed,":[61],"based":[64],"on":[65],"well-established":[66],"immunological":[67],"techniques,":[68],"which":[69],"known":[71,147],"last":[74],"year":[75],"great":[76],"advances":[77,180],"due":[78],"combination":[81],"highly":[83,199],"sensitive":[84,200],"tracers,":[85],"innovative":[86],"signal":[87],"amplification":[88,209],"strategies":[89,119],"last-generation":[91],"instrumental":[92],"detectors.":[93],"All":[94],"these":[95],"available":[96],"progresses":[97,197],"can":[98,155],"be":[99],"applied":[100],"also":[101,225],"adapting":[107],"them":[108],"portable":[111],"miniaturized":[113],"format.":[114],"This":[115],"possibility":[116],"opens":[117],"countless":[118],"definitively":[121],"turning":[122],"technique":[125],"into":[126],"an":[127],"method.":[130],"Among":[131],"different":[133],"proposals":[134],"achieving":[136],"goal,":[138],"use":[140],"enzyme-based":[142,208],"immunoassay":[143],"very":[145],"well":[146],"widespread":[149],"routine":[151],"it":[154],"represent":[156],"valid":[158],"approach":[159],"improving":[161],"performances.":[163],"Several":[164],"examples":[165],"been":[167],"recently":[168],"reported":[169],"literature":[171],"exploiting":[172],"enzymes":[173],"properties":[174],"features":[176,212],"obtaining":[178],"significative":[179],"field.":[183],"In":[184],"review,":[186],"we":[187],"aim":[188],"critical":[192],"overview":[193],"recent":[196],"detection":[202],"technologies,":[203,217],"involving":[204],"exploitation":[206],"strategies.":[210],"The":[211],"applications":[214],"along":[218],"with":[219],"future":[220],"developments":[221],"challenges,":[223],"discussed.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":7}],"updated_date":"2026-06-06T09:05:17.133730","created_date":"2025-10-10T00:00:00"}