{"id":"https://openalex.org/W3137573153","doi":"https://doi.org/10.3390/s21062230","title":"A Miniature Bio-Photonics Companion Diagnostics Platform for Reliable Cancer Treatment Monitoring in Blood Fluids","display_name":"A Miniature Bio-Photonics Companion Diagnostics Platform for Reliable Cancer Treatment Monitoring in Blood Fluids","publication_year":2021,"publication_date":"2021-03-23","ids":{"openalex":"https://openalex.org/W3137573153","doi":"https://doi.org/10.3390/s21062230","mag":"3137573153"},"language":"en","primary_location":{"id":"doi:10.3390/s21062230","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21062230","pdf_url":"https://www.mdpi.com/1424-8220/21/6/2230/pdf?version=1616485586","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/21/6/2230/pdf?version=1616485586","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080803882","display_name":"Marianneza Chatzipetrou","orcid":"https://orcid.org/0000-0002-5791-4394"},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]},{"id":"https://openalex.org/I4210144519","display_name":"Institute of Communication and Computer Systems","ror":"https://ror.org/0483fn738","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210144519"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Marianneza Chatzipetrou","raw_affiliation_strings":["Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0002-5791-4394","affiliations":[{"raw_affiliation_string":"Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece","institution_ids":["https://openalex.org/I4210144519","https://openalex.org/I174458059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040671228","display_name":"Lefteris Gounaridis","orcid":"https://orcid.org/0000-0002-2525-1565"},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]},{"id":"https://openalex.org/I4210144519","display_name":"Institute of Communication and Computer Systems","ror":"https://ror.org/0483fn738","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210144519"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Lefteris Gounaridis","raw_affiliation_strings":["Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0002-2525-1565","affiliations":[{"raw_affiliation_string":"Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece","institution_ids":["https://openalex.org/I4210144519","https://openalex.org/I174458059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064197372","display_name":"George Tsekenis","orcid":"https://orcid.org/0000-0002-5780-1074"},"institutions":[{"id":"https://openalex.org/I206127235","display_name":"Academy of Athens","ror":"https://ror.org/00qsdn986","country_code":"GR","type":"education","lineage":["https://openalex.org/I206127235"]},{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"George Tsekenis","raw_affiliation_strings":["Biomedical Research Foundation of the Academy of Athens, Soranou Ephessiou 4, 11527 Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0002-5780-1074","affiliations":[{"raw_affiliation_string":"Biomedical Research Foundation of the Academy of Athens, Soranou Ephessiou 4, 11527 Athens, Greece","institution_ids":["https://openalex.org/I206127235","https://openalex.org/I4210093138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082555387","display_name":"Maria Dimadi","orcid":null},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]},{"id":"https://openalex.org/I4210144519","display_name":"Institute of Communication and Computer Systems","ror":"https://ror.org/0483fn738","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210144519"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Maria Dimadi","raw_affiliation_strings":["Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece","institution_ids":["https://openalex.org/I4210144519","https://openalex.org/I174458059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067410864","display_name":"Rachel Vestering-Stenger","orcid":null},"institutions":[{"id":"https://openalex.org/I4210087004","display_name":"Future Diagnostics (Netherlands)","ror":"https://ror.org/001gdnj66","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210087004"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rachel Vestering-Stenger","raw_affiliation_strings":["Future Diagnostic Solutions B.V., Nieuweweg 279, 6603 BN Wijchen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Future Diagnostic Solutions B.V., Nieuweweg 279, 6603 BN Wijchen, The Netherlands","institution_ids":["https://openalex.org/I4210087004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029708859","display_name":"Erik Schreuder","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086120","display_name":"LioniX (Netherlands)","ror":"https://ror.org/00k8nkz10","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210086120"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Erik F. Schreuder","raw_affiliation_strings":["LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands","institution_ids":["https://openalex.org/I4210086120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017493831","display_name":"Anke K. Trilling","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anke Trilling","raw_affiliation_strings":["SurfiX B.V., Plus Ultra Building\u2014Bronland 12 B-1, 6708 WH Wageningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SurfiX B.V., Plus Ultra Building\u2014Bronland 12 B-1, 6708 WH Wageningen, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035098173","display_name":"G.A.J. Besselink","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086120","display_name":"LioniX (Netherlands)","ror":"https://ror.org/00k8nkz10","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210086120"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Geert Besselink","raw_affiliation_strings":["LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands","institution_ids":["https://openalex.org/I4210086120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036901380","display_name":"Luc Scheres","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luc Scheres","raw_affiliation_strings":["SurfiX B.V., Plus Ultra Building\u2014Bronland 12 B-1, 6708 WH Wageningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SurfiX B.V., Plus Ultra Building\u2014Bronland 12 B-1, 6708 WH Wageningen, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112508930","display_name":"Adriaan van der Meer","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adriaan van der Meer","raw_affiliation_strings":["SurfiX B.V., Plus Ultra Building\u2014Bronland 12 B-1, 6708 WH Wageningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SurfiX B.V., Plus Ultra Building\u2014Bronland 12 B-1, 6708 WH Wageningen, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080203235","display_name":"Ernst Lindhout","orcid":null},"institutions":[{"id":"https://openalex.org/I4210087004","display_name":"Future Diagnostics (Netherlands)","ror":"https://ror.org/001gdnj66","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210087004"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Ernst Lindhout","raw_affiliation_strings":["Future Diagnostic Solutions B.V., Nieuweweg 279, 6603 BN Wijchen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Future Diagnostic Solutions B.V., Nieuweweg 279, 6603 BN Wijchen, The Netherlands","institution_ids":["https://openalex.org/I4210087004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010915443","display_name":"Ren\u00e9 Heideman","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086120","display_name":"LioniX (Netherlands)","ror":"https://ror.org/00k8nkz10","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210086120"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rene G. Heideman","raw_affiliation_strings":["LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands","institution_ids":["https://openalex.org/I4210086120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067974133","display_name":"H. Leeuwis","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086120","display_name":"LioniX (Netherlands)","ror":"https://ror.org/00k8nkz10","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210086120"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Henk Leeuwis","raw_affiliation_strings":["LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LioniX International B.V., P.O. Box 456, 7500 AL Enschede, The Netherlands","institution_ids":["https://openalex.org/I4210086120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083671518","display_name":"Siegfried Graf","orcid":"https://orcid.org/0000-0002-9728-0234"},"institutions":[{"id":"https://openalex.org/I135218257","display_name":"Swiss Center for Electronics and Microtechnology (Switzerland)","ror":"https://ror.org/05nrrsx06","country_code":"CH","type":"company","lineage":["https://openalex.org/I135218257"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Siegfried Graf","raw_affiliation_strings":["CSEM SA, Untere Gr\u00fcndlistrasse 1, 6055 Alpnach, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-9728-0234","affiliations":[{"raw_affiliation_string":"CSEM SA, Untere Gr\u00fcndlistrasse 1, 6055 Alpnach, Switzerland","institution_ids":["https://openalex.org/I135218257"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113444716","display_name":"T. Volden","orcid":null},"institutions":[{"id":"https://openalex.org/I135218257","display_name":"Swiss Center for Electronics and Microtechnology (Switzerland)","ror":"https://ror.org/05nrrsx06","country_code":"CH","type":"company","lineage":["https://openalex.org/I135218257"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Tormod Volden","raw_affiliation_strings":["CSEM SA, Untere Gr\u00fcndlistrasse 1, 6055 Alpnach, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSEM SA, Untere Gr\u00fcndlistrasse 1, 6055 Alpnach, Switzerland","institution_ids":["https://openalex.org/I135218257"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005177933","display_name":"Michael Ningler","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Ningler","raw_affiliation_strings":["LRE Medical, Hofer Strasse 5, 86720 Noerdlingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LRE Medical, Hofer Strasse 5, 86720 Noerdlingen, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073760401","display_name":"Christos Kouloumentas","orcid":"https://orcid.org/0000-0001-8272-2581"},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]},{"id":"https://openalex.org/I4210144519","display_name":"Institute of Communication and Computer Systems","ror":"https://ror.org/0483fn738","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210144519"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Christos Kouloumentas","raw_affiliation_strings":["Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0001-8272-2581","affiliations":[{"raw_affiliation_string":"Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece","institution_ids":["https://openalex.org/I4210144519","https://openalex.org/I174458059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004382941","display_name":"Claudia Strehle","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claudia Strehle","raw_affiliation_strings":["LRE Medical, Hofer Strasse 5, 86720 Noerdlingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LRE Medical, Hofer Strasse 5, 86720 Noerdlingen, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011124600","display_name":"Vincent Revol","orcid":"https://orcid.org/0000-0002-0673-0683"},"institutions":[{"id":"https://openalex.org/I135218257","display_name":"Swiss Center for Electronics and Microtechnology (Switzerland)","ror":"https://ror.org/05nrrsx06","country_code":"CH","type":"company","lineage":["https://openalex.org/I135218257"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Vincent Revol","raw_affiliation_strings":["CSEM SA, Untere Gr\u00fcndlistrasse 1, 6055 Alpnach, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSEM SA, Untere Gr\u00fcndlistrasse 1, 6055 Alpnach, Switzerland","institution_ids":["https://openalex.org/I135218257"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063299411","display_name":"Apostolos Klinakis","orcid":"https://orcid.org/0000-0002-3923-861X"},"institutions":[{"id":"https://openalex.org/I206127235","display_name":"Academy of Athens","ror":"https://ror.org/00qsdn986","country_code":"GR","type":"education","lineage":["https://openalex.org/I206127235"]},{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Apostolos Klinakis","raw_affiliation_strings":["Biomedical Research Foundation of the Academy of Athens, Soranou Ephessiou 4, 11527 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Research Foundation of the Academy of Athens, Soranou Ephessiou 4, 11527 Athens, Greece","institution_ids":["https://openalex.org/I206127235","https://openalex.org/I4210093138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053874184","display_name":"H. Avramopoulos","orcid":"https://orcid.org/0000-0001-8793-2262"},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]},{"id":"https://openalex.org/I4210144519","display_name":"Institute of Communication and Computer Systems","ror":"https://ror.org/0483fn738","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210144519"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Hercules Avramopoulos","raw_affiliation_strings":["Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece","institution_ids":["https://openalex.org/I4210144519","https://openalex.org/I174458059"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007018398","display_name":"I. Zergioti","orcid":"https://orcid.org/0000-0001-6341-4495"},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]},{"id":"https://openalex.org/I4210144519","display_name":"Institute of Communication and Computer Systems","ror":"https://ror.org/0483fn738","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210144519"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Ioanna Zergioti","raw_affiliation_strings":["Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0001-6341-4495","affiliations":[{"raw_affiliation_string":"Institute of Communication and Computer Systems (ICCS), National Technical University of Athens, Heroon Polytehneiou 9, 15780 Athens, Greece","institution_ids":["https://openalex.org/I4210144519","https://openalex.org/I174458059"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":22,"corresponding_author_ids":["https://openalex.org/A5007018398"],"corresponding_institution_ids":["https://openalex.org/I174458059","https://openalex.org/I4210144519"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":1.1184,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.76859699,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"21","issue":"6","first_page":"2230","last_page":"2230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10299","display_name":"Photonic and Optical Devices","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10299","display_name":"Photonic and Optical Devices","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12224","display_name":"Nanofabrication and Lithography Techniques","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photonics","display_name":"Photonics","score":0.7606678009033203},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.6244279742240906},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5912793874740601},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5903488993644714},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.5160152912139893},{"id":"https://openalex.org/keywords/interferometry","display_name":"Interferometry","score":0.4623931646347046},{"id":"https://openalex.org/keywords/circulating-tumor-cell","display_name":"Circulating tumor cell","score":0.43720319867134094},{"id":"https://openalex.org/keywords/fluidics","display_name":"Fluidics","score":0.4337029457092285},{"id":"https://openalex.org/keywords/lab-on-a-chip","display_name":"Lab-on-a-chip","score":0.4189123511314392},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.34660956263542175},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.2442605197429657},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.1524212658405304},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.14321589469909668},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.0892685055732727}],"concepts":[{"id":"https://openalex.org/C20788544","wikidata":"https://www.wikidata.org/wiki/Q467054","display_name":"Photonics","level":2,"score":0.7606678009033203},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.6244279742240906},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5912793874740601},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5903488993644714},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.5160152912139893},{"id":"https://openalex.org/C166689943","wikidata":"https://www.wikidata.org/wiki/Q850283","display_name":"Interferometry","level":2,"score":0.4623931646347046},{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.43720319867134094},{"id":"https://openalex.org/C132651336","wikidata":"https://www.wikidata.org/wiki/Q185571","display_name":"Fluidics","level":2,"score":0.4337029457092285},{"id":"https://openalex.org/C138942068","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Lab-on-a-chip","level":3,"score":0.4189123511314392},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.34660956263542175},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2442605197429657},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1524212658405304},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.14321589469909668},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0892685055732727},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/s21062230","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21062230","pdf_url":"https://www.mdpi.com/1424-8220/21/6/2230/pdf?version=1616485586","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:44c58483bc9d4f509e3968f71a0c0dc6","is_oa":true,"landing_page_url":"https://doaj.org/article/44c58483bc9d4f509e3968f71a0c0dc6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 21, Iss 6, p 2230 (2021)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1424-8220/21/6/2230/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s21062230","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 21; Issue 6; Pages: 2230","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8005058","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8005058","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s21062230","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s21062230","pdf_url":"https://www.mdpi.com/1424-8220/21/6/2230/pdf?version=1616485586","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1111162366","display_name":null,"funder_award_id":"732309","funder_id":"https://openalex.org/F4320337663","funder_display_name":"H2020 Industrial Leadership"}],"funders":[{"id":"https://openalex.org/F4320337663","display_name":"H2020 Industrial Leadership","ror":null}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3137573153.pdf"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1983333664","https://openalex.org/W1985597408","https://openalex.org/W1993020585","https://openalex.org/W2009903047","https://openalex.org/W2040254040","https://openalex.org/W2047639939","https://openalex.org/W2060272389","https://openalex.org/W2093537273","https://openalex.org/W2093921289","https://openalex.org/W2164697448","https://openalex.org/W2330783767","https://openalex.org/W2470975360","https://openalex.org/W2495935064","https://openalex.org/W2515382171","https://openalex.org/W2552372328","https://openalex.org/W2560691444","https://openalex.org/W2564765455","https://openalex.org/W2600040193","https://openalex.org/W2611858402","https://openalex.org/W2751522122","https://openalex.org/W2801417756","https://openalex.org/W2883500730","https://openalex.org/W2920083856","https://openalex.org/W3008408291"],"related_works":["https://openalex.org/W4385923988","https://openalex.org/W130619353","https://openalex.org/W2808489040","https://openalex.org/W2055686434","https://openalex.org/W2939039077","https://openalex.org/W2140522072","https://openalex.org/W2021085378","https://openalex.org/W4298071810","https://openalex.org/W2733260917","https://openalex.org/W2185392992"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"we":[3],"present":[4],"the":[5,28,70,76,80,85,88,91,97,101,111,131,139,189,192],"development":[6,140],"of":[7,57,79,87,100,135,141,164,191],"a":[8,17,121],"photonic":[9,50],"biosensor":[10,145],"device":[11,23,146,153],"for":[12],"cancer":[13,157,179,185],"treatment":[14],"monitoring":[15],"as":[16],"complementary":[18],"diagnostics":[19],"tool.":[20],"The":[21,49,152,162],"proposed":[22],"combines":[24],"multidisciplinary":[25],"concepts":[26],"from":[27],"photonic,":[29],"nano-biochemical,":[30],"micro-fluidic":[31],"and":[32,46,69,130,167],"reader/packaging":[33],"platforms":[34],"aiming":[35],"to":[36,40,96,110],"overcome":[37],"limitations":[38],"related":[39],"detection":[41,163],"reliability,":[42],"sensitivity,":[43],"specificity,":[44],"compactness":[45],"cost":[47],"issues.":[48],"sensor":[51],"is":[52,72,106,118,154,182],"based":[53],"on":[54,65,90],"an":[55,103,142],"array":[56],"six":[58],"asymmetric":[59],"Mach":[60],"Zender":[61],"Interferometer":[62],"(aMZI)":[63],"waveguides":[64],"silicon":[66],"nitride":[67],"substrates":[68],"sensing":[71],"performed":[73],"by":[74,84,178],"measuring":[75],"phase":[77],"shift":[78],"output":[81],"signal,":[82],"caused":[83],"binding":[86],"analyte":[89],"functionalized":[92],"aMZI":[93],"surface.":[94],"According":[95],"morphological":[98],"design":[99],"waveguides,":[102],"improved":[104],"sensitivity":[105],"achieved":[107,183],"in":[108,138,184],"comparison":[109],"current":[112],"technologies":[113],"(<5000":[114],"nm/RIU).":[115],"This":[116],"platform":[117],"combined":[119],"with":[120,156,188],"novel":[122],"biofunctionalization":[123],"methodology":[124],"that":[125,147],"involves":[126],"material-selective":[127],"surface":[128],"chemistries":[129],"high-resolution":[132],"laser":[133],"printing":[134],"biomaterials":[136],"resulting":[137],"integrated":[143],"photonics":[144],"employs":[148],"disposable":[149],"microfluidics":[150],"cartridges.":[151],"tested":[155],"patient":[158,186],"blood":[159],"serum":[160,187],"samples.":[161],"periostin":[165],"(POSTN)":[166],"transforming":[168],"growth":[169],"factor":[170],"beta-induced":[171],"protein":[172],"(TGFBI),":[173],"two":[174],"circulating":[175],"biomarkers":[176],"overexpressed":[177],"stem":[180],"cells,":[181],"use":[190],"device.":[193]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-05-22T06:13:13.366637","created_date":"2021-03-29T00:00:00"}