{"id":"https://openalex.org/W3064045486","doi":"https://doi.org/10.3390/s20174667","title":"Rapid Detection of \u03b2-Lactamase-Producing Bacteria Using the Integrated Comprehensive Droplet Digital Detection (IC 3D) System","display_name":"Rapid Detection of \u03b2-Lactamase-Producing Bacteria Using the Integrated Comprehensive Droplet Digital Detection (IC 3D) System","publication_year":2020,"publication_date":"2020-08-19","ids":{"openalex":"https://openalex.org/W3064045486","doi":"https://doi.org/10.3390/s20174667","mag":"3064045486","pmid":"https://pubmed.ncbi.nlm.nih.gov/32824984"},"language":"en","primary_location":{"id":"doi:10.3390/s20174667","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s20174667","pdf_url":"https://www.mdpi.com/1424-8220/20/17/4667/pdf?version=1597827961","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/20/17/4667/pdf?version=1597827961","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101498205","display_name":"Yiyan Li","orcid":"https://orcid.org/0000-0002-1682-1108"},"institutions":[{"id":"https://openalex.org/I149471917","display_name":"Fort Lewis College","ror":"https://ror.org/00aad7q36","country_code":"US","type":"education","lineage":["https://openalex.org/I149471917"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yiyan Li","raw_affiliation_strings":["Department of Physics and Engineering, Fort Lewis College, Durango, CO 81301, USA"],"raw_orcid":"https://orcid.org/0000-0002-1682-1108","affiliations":[{"raw_affiliation_string":"Department of Physics and Engineering, Fort Lewis College, Durango, CO 81301, USA","institution_ids":["https://openalex.org/I149471917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033169683","display_name":"Hemanth Cherukury","orcid":"https://orcid.org/0000-0001-5719-7914"},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hemanth Cherukury","raw_affiliation_strings":["Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697, USA","Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080476711","display_name":"Louai Labanieh","orcid":"https://orcid.org/0000-0003-3998-7415"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Louai Labanieh","raw_affiliation_strings":["Department of Bioengineering, Stanford University, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, Stanford University, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006229115","display_name":"Weian Zhao","orcid":"https://orcid.org/0000-0002-7794-9914"},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]},{"id":"https://openalex.org/I4210155533","display_name":"Edwards Lifesciences (United States)","ror":"https://ror.org/04jhyte11","country_code":"US","type":"company","lineage":["https://openalex.org/I4210155533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Weian Zhao","raw_affiliation_strings":["Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA 92697, USA","Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA","Department of Biomedical Engineering, University of California Irvine, Irvine, CA 92697, USA","Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697, USA","Edwards Life Sciences Center for Advanced Cardiovascular Technology, University of California Irvine, Irvine, CA 92697, USA","Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Edwards Life Sciences Center for Advanced Cardiovascular Technology, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I4210155533","https://openalex.org/I204250578"]},{"raw_affiliation_string":"Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, USA","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085744004","display_name":"Dong\u2010Ku Kang","orcid":"https://orcid.org/0000-0003-1261-6446"},"institutions":[{"id":"https://openalex.org/I146429904","display_name":"Incheon National University","ror":"https://ror.org/02xf7p935","country_code":"KR","type":"education","lineage":["https://openalex.org/I146429904"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Dong-Ku Kang","raw_affiliation_strings":["Department of Chemistry, Incheon National University, Incheon 22012, Korea","Research Institute of Basic Sciences, Incheon National University, Incheon 22012, Korea"],"raw_orcid":"https://orcid.org/0000-0003-1261-6446","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Incheon National University, Incheon 22012, Korea","institution_ids":["https://openalex.org/I146429904"]},{"raw_affiliation_string":"Research Institute of Basic Sciences, Incheon National University, Incheon 22012, Korea","institution_ids":["https://openalex.org/I146429904"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5085744004"],"corresponding_institution_ids":["https://openalex.org/I146429904"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":0.6968,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.66562802,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"20","issue":"17","first_page":"4667","last_page":"4667"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.7848812341690063},{"id":"https://openalex.org/keywords/detection-limit","display_name":"Detection limit","score":0.7033618688583374},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.579811692237854},{"id":"https://openalex.org/keywords/particle","display_name":"Particle (ecology)","score":0.5209164023399353},{"id":"https://openalex.org/keywords/digital-polymerase-chain-reaction","display_name":"Digital polymerase chain reaction","score":0.4909386932849884},{"id":"https://openalex.org/keywords/antibiotics","display_name":"Antibiotics","score":0.48820048570632935},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.4429609775543213},{"id":"https://openalex.org/keywords/bacterial-cell-structure","display_name":"Bacterial cell structure","score":0.43770167231559753},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.39454925060272217},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3698265850543976},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3182308077812195},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.3150344491004944},{"id":"https://openalex.org/keywords/polymerase-chain-reaction","display_name":"Polymerase chain reaction","score":0.3032383322715759},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2943926453590393},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.13196486234664917}],"concepts":[{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.7848812341690063},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.7033618688583374},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.579811692237854},{"id":"https://openalex.org/C2778517922","wikidata":"https://www.wikidata.org/wiki/Q7140482","display_name":"Particle (ecology)","level":2,"score":0.5209164023399353},{"id":"https://openalex.org/C48126324","wikidata":"https://www.wikidata.org/wiki/Q5276136","display_name":"Digital polymerase chain reaction","level":4,"score":0.4909386932849884},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.48820048570632935},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4429609775543213},{"id":"https://openalex.org/C19655278","wikidata":"https://www.wikidata.org/wiki/Q3293735","display_name":"Bacterial cell structure","level":3,"score":0.43770167231559753},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.39454925060272217},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3698265850543976},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3182308077812195},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3150344491004944},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.3032383322715759},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2943926453590393},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13196486234664917},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.3390/s20174667","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s20174667","pdf_url":"https://www.mdpi.com/1424-8220/20/17/4667/pdf?version=1597827961","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:32824984","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32824984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:ark:/13030/qt7027k0xg","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:doaj.org/article:efbd08aff06e4da5b27a45a0f320d109","is_oa":true,"landing_page_url":"https://doaj.org/article/efbd08aff06e4da5b27a45a0f320d109","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 20, Iss 17, p 4667 (2020)","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt7027k0xg","is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/7027k0xg","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, vol 20, iss 17","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1424-8220/20/17/4667/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s20174667","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 20; Issue 17; Pages: 4667","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7506896","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7506896","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s20174667","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s20174667","pdf_url":"https://www.mdpi.com/1424-8220/20/17/4667/pdf?version=1597827961","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3064045486.pdf"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1832113087","https://openalex.org/W1959447435","https://openalex.org/W1997337200","https://openalex.org/W1998302401","https://openalex.org/W2010686122","https://openalex.org/W2015294314","https://openalex.org/W2040654803","https://openalex.org/W2051577725","https://openalex.org/W2060775802","https://openalex.org/W2111674526","https://openalex.org/W2154602368","https://openalex.org/W2181262698","https://openalex.org/W2422645007","https://openalex.org/W2463871935","https://openalex.org/W2559322511","https://openalex.org/W2581858901","https://openalex.org/W2724317418","https://openalex.org/W2751960520","https://openalex.org/W2787977934","https://openalex.org/W2790737890","https://openalex.org/W2799759495","https://openalex.org/W2801360758","https://openalex.org/W2883566781","https://openalex.org/W2884524290","https://openalex.org/W2914960150","https://openalex.org/W2920888242","https://openalex.org/W2949897498","https://openalex.org/W2979110830","https://openalex.org/W2981913846","https://openalex.org/W2996713594","https://openalex.org/W2998853022"],"related_works":["https://openalex.org/W2316397625","https://openalex.org/W2112992429","https://openalex.org/W2521321542","https://openalex.org/W2888471476","https://openalex.org/W2113559596","https://openalex.org/W3103016203","https://openalex.org/W4289731913","https://openalex.org/W4377103828","https://openalex.org/W2897123201","https://openalex.org/W903810529"],"abstract_inverted_index":{"Antibiotic-resistant":[0],"bacteria":[1,41,79,217],"have":[2],"emerged":[3],"as":[4],"an":[5],"imminent":[6],"global":[7],"threat.":[8],"The":[9,33,144],"lack":[10],"of":[11,31,66,134,138,181,191,215],"rapid":[12],"and":[13,27,44,51,92,109,116,157,193],"sensitive":[14],"diagnostic":[15],"techniques":[16],"leaves":[17],"health":[18],"care":[19],"providers":[20],"with":[21,126],"inadequate":[22],"resources":[23],"for":[24,38,62,76,212],"guiding":[25],"therapy":[26],"risks":[28],"the":[29,63,106,117,127,158,179,194,213,219],"lives":[30],"patients.":[32],"traditional":[34],"plate":[35],"culturing":[36],"methods":[37],"identifying":[39],"antibiotic-resistant":[40],"is":[42,60,132],"laborious":[43],"time-consuming.":[45],"Bulk":[46],"PCR":[47],"(Polymerase":[48],"Chain":[49],"Reaction)":[50],"qPCR":[52],"are":[53],"limited":[54],"by":[55],"poor":[56],"detection":[57,65,182,214],"sensitivity,":[58],"which":[59,131,168],"critical":[61],"early-stage":[64],"bloodstream":[67],"infections.":[68],"In":[69,176],"this":[70,177],"study,":[71],"we":[72],"introduce":[73],"a":[74,85,93,209],"technique":[75],"detecting":[77],"\u03b2-lactamase-producing":[78,216],"at":[80,105],"single-cell":[81,107],"sensitivity":[82],"based":[83],"on":[84],"commercial":[86],"\u03b2-lactamase":[87],"sensor":[88],"(Fluorocillin),":[89],"droplet":[90],"microfluidics,":[91],"custom":[94],"3D":[95,128,159,223],"particle":[96,129],"counter.":[97],"Bacteria-containing":[98],"samples":[99],"were":[100,123],"encapsulated":[101],"within":[102,111,141],"picoliter-sized":[103],"droplets":[104,113,122,140,149],"level":[108],"cultured":[110],"water-in-oil":[112],"containing":[114],"antibiotics":[115],"Fluorocillin":[118],"sensor.":[119],"Then,":[120],"fluorescent":[121],"digitally":[124],"quantified":[125],"counter,":[130],"capable":[133],"analyzing":[135],"milliliter-scale":[136],"volumes":[137],"collected":[139],"10":[142,166,186],"min.":[143],"fluorescence":[145],"signal":[146],"from":[147,197],"single-colony":[148],"was":[150,161,169,184,201],"detectable":[151],"in":[152,163],"less":[153,164,202],"than":[154,165,172,203],"5":[155],"h,":[156],"scanning":[160],"performed":[162],"min,":[167],"significantly":[170],"faster":[171],"conventional":[173],"culture-based":[174],"methods.":[175],"approach,":[178],"limit":[180],"achieved":[183],"about":[185],"bacterial":[187],"cells":[188],"per":[189],"mL":[190],"sample,":[192],"turnaround":[195],"time":[196],"sample":[198],"to":[199],"result":[200],"6":[204],"h.":[205],"This":[206],"study":[207],"demonstrates":[208],"promising":[210],"strategy":[211],"using":[218],"recently":[220],"developed":[221],"IC":[222],"system.":[224]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1}],"updated_date":"2026-05-22T06:13:13.366637","created_date":"2025-10-10T00:00:00"}