{"id":"https://openalex.org/W2999175977","doi":"https://doi.org/10.3390/s20020497","title":"Monitoring Biochemical and Structural Changes in Human Periodontal Ligaments during Orthodontic Treatment by Means of Micro-Raman Spectroscopy","display_name":"Monitoring Biochemical and Structural Changes in Human Periodontal Ligaments during Orthodontic Treatment by Means of Micro-Raman Spectroscopy","publication_year":2020,"publication_date":"2020-01-15","ids":{"openalex":"https://openalex.org/W2999175977","doi":"https://doi.org/10.3390/s20020497","mag":"2999175977","pmid":"https://pubmed.ncbi.nlm.nih.gov/31952367"},"language":"en","primary_location":{"id":"doi:10.3390/s20020497","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s20020497","pdf_url":"https://www.mdpi.com/1424-8220/20/2/497/pdf?version=1579599691","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/20/2/497/pdf?version=1579599691","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074578841","display_name":"Letizia Perillo","orcid":"https://orcid.org/0000-0001-6175-7363"},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Letizia Perillo","raw_affiliation_strings":["Dipartimento Multidisciplinare di Specialit\u00e0 Medico-Chirurgiche e Odontoiatriche, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy"],"raw_orcid":"https://orcid.org/0000-0001-6175-7363","affiliations":[{"raw_affiliation_string":"Dipartimento Multidisciplinare di Specialit\u00e0 Medico-Chirurgiche e Odontoiatriche, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086180727","display_name":"Fabrizia d\u2019Apuzzo","orcid":"https://orcid.org/0000-0003-0291-9339"},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabrizia d\u2019Apuzzo","raw_affiliation_strings":["Dipartimento Multidisciplinare di Specialit\u00e0 Medico-Chirurgiche e Odontoiatriche, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy"],"raw_orcid":"https://orcid.org/0000-0003-0291-9339","affiliations":[{"raw_affiliation_string":"Dipartimento Multidisciplinare di Specialit\u00e0 Medico-Chirurgiche e Odontoiatriche, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053393287","display_name":"Maddalena Illario","orcid":"https://orcid.org/0000-0001-9834-6517"},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maddalena Illario","raw_affiliation_strings":["Dipartimento di Scienze Mediche Traslazionali, Universit\u00e0 degli Studi di Napoli Federico II, 80131 Napoli, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9834-6517","affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Mediche Traslazionali, Universit\u00e0 degli Studi di Napoli Federico II, 80131 Napoli, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045800539","display_name":"Luigi Laino","orcid":"https://orcid.org/0000-0003-2372-7109"},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigi Laino","raw_affiliation_strings":["Dipartimento Multidisciplinare di Specialit\u00e0 Medico-Chirurgiche e Odontoiatriche, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Multidisciplinare di Specialit\u00e0 Medico-Chirurgiche e Odontoiatriche, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016931755","display_name":"Gaetano Di Spigna","orcid":"https://orcid.org/0000-0003-4590-1753"},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gaetano Di Spigna","raw_affiliation_strings":["Dipartimento di Scienze Mediche Traslazionali, Universit\u00e0 degli Studi di Napoli Federico II, 80131 Napoli, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Mediche Traslazionali, Universit\u00e0 degli Studi di Napoli Federico II, 80131 Napoli, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063669304","display_name":"Maria Lepore","orcid":"https://orcid.org/0000-0003-2743-5904"},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Maria Lepore","raw_affiliation_strings":["Dipartimento di Medicina Sperimentale, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy"],"raw_orcid":"https://orcid.org/0000-0003-2743-5904","affiliations":[{"raw_affiliation_string":"Dipartimento di Medicina Sperimentale, Universit\u00e0 degli Studi della Campania Luigi Vanvitelli, 80138 Napoli, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043394842","display_name":"C. Camerlingo","orcid":"https://orcid.org/0000-0002-6014-0588"},"institutions":[{"id":"https://openalex.org/I4210095637","display_name":"Superconducting and other Innovative Materials and Devices Institute","ror":"https://ror.org/00p03yg71","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210095637","https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carlo Camerlingo","raw_affiliation_strings":["CNR-SPIN, Istituto Superconduttori, Materiali Innovativi e Dispositivi, 80078 Pozzuoli, Italy"],"raw_orcid":"https://orcid.org/0000-0002-6014-0588","affiliations":[{"raw_affiliation_string":"CNR-SPIN, Istituto Superconduttori, Materiali Innovativi e Dispositivi, 80078 Pozzuoli, Italy","institution_ids":["https://openalex.org/I4210095637"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5063669304"],"corresponding_institution_ids":["https://openalex.org/I197809005"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":3.8403,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.93288009,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"20","issue":"2","first_page":"497","last_page":"497"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11386","display_name":"Bee Products Chemical Analysis","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/periodontal-fiber","display_name":"Periodontal fiber","score":0.9097282290458679},{"id":"https://openalex.org/keywords/raman-spectroscopy","display_name":"Raman spectroscopy","score":0.7343417406082153},{"id":"https://openalex.org/keywords/premolar","display_name":"Premolar","score":0.6941903233528137},{"id":"https://openalex.org/keywords/molar","display_name":"Molar","score":0.5823172926902771},{"id":"https://openalex.org/keywords/dentistry","display_name":"Dentistry","score":0.5084520578384399},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5080282688140869},{"id":"https://openalex.org/keywords/orthodontics","display_name":"Orthodontics","score":0.44924208521842957},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.35672256350517273},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3291766941547394},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.16797515749931335}],"concepts":[{"id":"https://openalex.org/C41868710","wikidata":"https://www.wikidata.org/wiki/Q540092","display_name":"Periodontal fiber","level":2,"score":0.9097282290458679},{"id":"https://openalex.org/C40003534","wikidata":"https://www.wikidata.org/wiki/Q862228","display_name":"Raman spectroscopy","level":2,"score":0.7343417406082153},{"id":"https://openalex.org/C2780641865","wikidata":"https://www.wikidata.org/wiki/Q839483","display_name":"Premolar","level":3,"score":0.6941903233528137},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.5823172926902771},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.5084520578384399},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5080282688140869},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.44924208521842957},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.35672256350517273},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3291766941547394},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16797515749931335},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014087","descriptor_name":"Tooth Movement Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014087","descriptor_name":"Tooth Movement Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014087","descriptor_name":"Tooth Movement Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014087","descriptor_name":"Tooth Movement Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/s20020497","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s20020497","pdf_url":"https://www.mdpi.com/1424-8220/20/2/497/pdf?version=1579599691","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:31952367","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31952367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:7290ac1a329a4577b5088b41fff8b043","is_oa":true,"landing_page_url":"https://doaj.org/article/7290ac1a329a4577b5088b41fff8b043","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 20, Iss 2, p 497 (2020)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:6007217","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7014419","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:mdpi.com:/1424-8220/20/2/497/","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/s20020497","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s20020497","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s20020497","pdf_url":"https://www.mdpi.com/1424-8220/20/2/497/pdf?version=1579599691","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46000000834465027}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2999175977.pdf","grobid_xml":"https://content.openalex.org/works/W2999175977.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W620458739","https://openalex.org/W1503891518","https://openalex.org/W1573616466","https://openalex.org/W1896170975","https://openalex.org/W1964794992","https://openalex.org/W1984675243","https://openalex.org/W1988103273","https://openalex.org/W1989696800","https://openalex.org/W1996190425","https://openalex.org/W2007362470","https://openalex.org/W2015200624","https://openalex.org/W2027553152","https://openalex.org/W2029775639","https://openalex.org/W2032521404","https://openalex.org/W2033902938","https://openalex.org/W2036953590","https://openalex.org/W2039871421","https://openalex.org/W2048950875","https://openalex.org/W2056436418","https://openalex.org/W2061097390","https://openalex.org/W2073039991","https://openalex.org/W2076120607","https://openalex.org/W2080044233","https://openalex.org/W2081579820","https://openalex.org/W2085337922","https://openalex.org/W2089170541","https://openalex.org/W2098727165","https://openalex.org/W2103444360","https://openalex.org/W2104253204","https://openalex.org/W2157552380","https://openalex.org/W2163443752","https://openalex.org/W2171847458","https://openalex.org/W2203038906","https://openalex.org/W2295097024","https://openalex.org/W2485412989","https://openalex.org/W2522545358","https://openalex.org/W2539651361","https://openalex.org/W2560510527","https://openalex.org/W2767729357","https://openalex.org/W2884914945","https://openalex.org/W3101398504","https://openalex.org/W4238768614","https://openalex.org/W4245716271","https://openalex.org/W6664349045"],"related_works":["https://openalex.org/W4225388957","https://openalex.org/W2392513340","https://openalex.org/W2349415424","https://openalex.org/W2090163517","https://openalex.org/W1862450294","https://openalex.org/W1719901275","https://openalex.org/W2386367413","https://openalex.org/W4367670394","https://openalex.org/W2339341772","https://openalex.org/W2599884875"],"abstract_inverted_index":{"The":[0,177],"aim":[1],"of":[2,77,107,118,149,206],"the":[3,8,15,56,81,105,113,138,142,160],"study":[4],"was":[5,53,94,152],"to":[6,170],"examine":[7],"biochemical":[9],"and":[10,29,58,74,88,112,122,126,129,163,173,193],"structural":[11],"changes":[12,156],"occurring":[13,208],"in":[14,104,141,159,196],"periodontal":[16,197],"ligament":[17],"(PDL)":[18],"during":[19],"orthodontic-force":[20,150],"application":[21,151],"using":[22,48],"micro-Raman":[23],"spectroscopy":[24],"(":[25],"\u03bc":[26,182],"-RS).":[27],"Adolescent":[28],"young":[30],"patients":[31],"who":[32],"needed":[33],"orthodontic":[34,44,200],"treatment":[35],"with":[36,92],"first":[37],"premolar":[38],"extractions":[39,68],"were":[40,46,61,69,86,98,133,157],"recruited.":[41],"Before":[42],"extractions,":[43],"forces":[45],"applied":[47],"a":[49,89,185],"closed-coil":[50],"spring":[51],"that":[52,137,181],"positioned":[54],"between":[55],"molar":[57],"premolar.":[59],"Patients":[60],"randomly":[62],"divided":[63],"into":[64],"three":[65],"groups,":[66],"whose":[67],"performed":[70],"after":[71,145,199],"2,":[72],"7,":[73],"14":[75],"days":[76],"force":[78,175],"application.":[79],"From":[80],"extracted":[82],"premolars,":[83],"PDL":[84,102,143,210],"samples":[85,144],"obtained,":[87],"fixation":[90],"procedure":[91],"paraformaldehyde":[93],"adopted.":[95],"Raman":[96],"spectra":[97],"acquired":[99],"for":[100,188,209],"each":[101],"sample":[103],"range":[106],"1000-3200":[108],"cm":[109],"-":[110],"1":[111],"more":[114],"relevant":[115],"vibrational":[116],"modes":[117,132],"proteins":[119],"(Amide":[120],"I":[121],"Amide":[123],"III":[124],"bands)":[125],"CH":[127,130,161,164],"2":[128,162],"3":[131,165],"shown.":[134],"Analysis":[135],"indicated":[136,180],"protein":[139],"structure":[140],"different":[146],"time":[147,207],"points":[148],"modified.":[153],"In":[154],"addition,":[155],"observed":[158],"high":[166],"wavenumber":[167],"region":[168],"due":[169],"local":[171],"hypoxia":[172],"mechanical":[174],"transduction.":[176],"reported":[178],"results":[179],"-RS":[183],"provides":[184],"valuable":[186],"tool":[187],"investigating":[189],"molecular":[190,211],"interchain":[191],"interactions":[192],"conformational":[194],"modifications":[195],"fibers":[198],"tooth":[201],"movement,":[202],"providing":[203],"quantitative":[204],"insight":[205],"readjustment.":[212]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}