{"id":"https://openalex.org/W2995888434","doi":"https://doi.org/10.3390/s19245435","title":"Application of Electrochemical Aptasensors toward Clinical Diagnostics, Food, and Environmental Monitoring: Review","display_name":"Application of Electrochemical Aptasensors toward Clinical Diagnostics, Food, and Environmental Monitoring: Review","publication_year":2019,"publication_date":"2019-12-10","ids":{"openalex":"https://openalex.org/W2995888434","doi":"https://doi.org/10.3390/s19245435","mag":"2995888434","pmid":"https://pubmed.ncbi.nlm.nih.gov/31835479"},"language":"en","primary_location":{"id":"doi:10.3390/s19245435","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s19245435","pdf_url":"https://www.mdpi.com/1424-8220/19/24/5435/pdf?version=1575966800","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/19/24/5435/pdf?version=1575966800","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031234546","display_name":"Zhanhong Li","orcid":"https://orcid.org/0000-0002-3552-7545"},"institutions":[{"id":"https://openalex.org/I135905480","display_name":"Shanghai Polytechnic University","ror":"https://ror.org/02as5yg64","country_code":"CN","type":"education","lineage":["https://openalex.org/I135905480"]},{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhanhong Li","raw_affiliation_strings":["Research Center of Resource Recycling Science and Engineering, Shanghai Polytechnic University, Shanghai 201209, China","School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China","School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China"],"affiliations":[{"raw_affiliation_string":"Research Center of Resource Recycling Science and Engineering, Shanghai Polytechnic University, Shanghai 201209, China","institution_ids":["https://openalex.org/I135905480"]},{"raw_affiliation_string":"School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China","institution_ids":["https://openalex.org/I135905480"]},{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112384933","display_name":"Mona A. Mohamed","orcid":null},"institutions":[{"id":"https://openalex.org/I4210136593","display_name":"National Organization for Drug Control and Research","ror":"https://ror.org/0407ex783","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210136593","https://openalex.org/I4210160667"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mona A. Mohamed","raw_affiliation_strings":["Pharmaceutical Chemistry Dept., National Organization for Drug Control and Research [NODCAR], 6 Abu Hazem Street, Pyramids Ave, 29, Giza 99999, Egypt"],"affiliations":[{"raw_affiliation_string":"Pharmaceutical Chemistry Dept., National Organization for Drug Control and Research [NODCAR], 6 Abu Hazem Street, Pyramids Ave, 29, Giza 99999, Egypt","institution_ids":["https://openalex.org/I4210136593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091277276","display_name":"A. M. Vinu Mohan","orcid":"https://orcid.org/0000-0002-6335-4426"},"institutions":[{"id":"https://openalex.org/I106349282","display_name":"Central Electrochemical Research Institute","ror":"https://ror.org/01qek3q18","country_code":"IN","type":"facility","lineage":["https://openalex.org/I106349282","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"A. M. Vinu Mohan","raw_affiliation_strings":["Electrodics & Electrocatalysis Division, CSIR-Central Electrochemical Research Institute (CECRI), Karaikudi 630003, Tamil Nadu, India"],"affiliations":[{"raw_affiliation_string":"Electrodics & Electrocatalysis Division, CSIR-Central Electrochemical Research Institute (CECRI), Karaikudi 630003, Tamil Nadu, India","institution_ids":["https://openalex.org/I106349282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008774513","display_name":"Zhigang Zhu","orcid":"https://orcid.org/0000-0002-0911-179X"},"institutions":[{"id":"https://openalex.org/I135905480","display_name":"Shanghai Polytechnic University","ror":"https://ror.org/02as5yg64","country_code":"CN","type":"education","lineage":["https://openalex.org/I135905480"]},{"id":"https://openalex.org/I148128674","display_name":"University of Shanghai for Science and Technology","ror":"https://ror.org/00ay9v204","country_code":"CN","type":"education","lineage":["https://openalex.org/I148128674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhigang Zhu","raw_affiliation_strings":["Research Center of Resource Recycling Science and Engineering, Shanghai Polytechnic University, Shanghai 201209, China","School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China","School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China"],"affiliations":[{"raw_affiliation_string":"Research Center of Resource Recycling Science and Engineering, Shanghai Polytechnic University, Shanghai 201209, China","institution_ids":["https://openalex.org/I135905480"]},{"raw_affiliation_string":"School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China","institution_ids":["https://openalex.org/I135905480"]},{"raw_affiliation_string":"School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China","institution_ids":["https://openalex.org/I148128674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102978427","display_name":"Vinay Sharma","orcid":"https://orcid.org/0000-0002-8834-702X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vinay Sharma","raw_affiliation_strings":["Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, India"],"affiliations":[{"raw_affiliation_string":"Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036909012","display_name":"Geetesh K. Mishra","orcid":"https://orcid.org/0000-0002-4179-6207"},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Geetesh K. Mishra","raw_affiliation_strings":["Multiscale Fluid Mechanics Lab, School of Mechanical Engineering, Sungkyunkwan University, Suwon 44-746, Korea"],"affiliations":[{"raw_affiliation_string":"Multiscale Fluid Mechanics Lab, School of Mechanical Engineering, Sungkyunkwan University, Suwon 44-746, Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075560178","display_name":"Rupesh K. Mishra","orcid":"https://orcid.org/0000-0002-4655-2762"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rupesh K. Mishra","raw_affiliation_strings":["Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, India"],"affiliations":[{"raw_affiliation_string":"Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5036909012","https://openalex.org/A5075560178"],"corresponding_institution_ids":["https://openalex.org/I848706"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":4.4543,"has_fulltext":true,"cited_by_count":116,"citation_normalized_percentile":{"value":0.95644487,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"19","issue":"24","first_page":"5435","last_page":"5435"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aptamer","display_name":"Aptamer","score":0.987037181854248},{"id":"https://openalex.org/keywords/systematic-evolution-of-ligands-by-exponential-enrichment","display_name":"Systematic evolution of ligands by exponential enrichment","score":0.6322346925735474},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.5710839033126831},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5697296857833862},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.547704815864563},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43693244457244873},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.38332611322402954},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21705570816993713},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.1770196557044983},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.17643585801124573},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.16207361221313477},{"id":"https://openalex.org/keywords/molecular-biology","display_name":"Molecular biology","score":0.09451478719711304},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.07332393527030945}],"concepts":[{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.987037181854248},{"id":"https://openalex.org/C122682173","wikidata":"https://www.wikidata.org/wiki/Q907101","display_name":"Systematic evolution of ligands by exponential enrichment","level":4,"score":0.6322346925735474},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.5710839033126831},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5697296857833862},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.547704815864563},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43693244457244873},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38332611322402954},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21705570816993713},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.1770196557044983},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.17643585801124573},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.16207361221313477},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.09451478719711304},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07332393527030945},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005504","descriptor_name":"Food Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005504","descriptor_name":"Food Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005504","descriptor_name":"Food Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D052156","descriptor_name":"SELEX Aptamer Technique","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D052156","descriptor_name":"SELEX Aptamer Technique","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D052156","descriptor_name":"SELEX Aptamer Technique","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D057089","descriptor_name":"Pathology, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057089","descriptor_name":"Pathology, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057089","descriptor_name":"Pathology, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3390/s19245435","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s19245435","pdf_url":"https://www.mdpi.com/1424-8220/19/24/5435/pdf?version=1575966800","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:31835479","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31835479","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:mdpi.com:/1424-8220/19/24/5435/","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/s19245435","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6960919","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6960919","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s19245435","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s19245435","pdf_url":"https://www.mdpi.com/1424-8220/19/24/5435/pdf?version=1575966800","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2995888434.pdf","grobid_xml":"https://content.openalex.org/works/W2995888434.grobid-xml"},"referenced_works_count":112,"referenced_works":["https://openalex.org/W1141462211","https://openalex.org/W1799417677","https://openalex.org/W1850250041","https://openalex.org/W1921158802","https://openalex.org/W1971193272","https://openalex.org/W1979377436","https://openalex.org/W1985788901","https://openalex.org/W1986040991","https://openalex.org/W1986585549","https://openalex.org/W1987786745","https://openalex.org/W1989913005","https://openalex.org/W1992611878","https://openalex.org/W1993324100","https://openalex.org/W1995227621","https://openalex.org/W2000973947","https://openalex.org/W2001868833","https://openalex.org/W2004638774","https://openalex.org/W2005187182","https://openalex.org/W2014935667","https://openalex.org/W2017079536","https://openalex.org/W2021014727","https://openalex.org/W2023057504","https://openalex.org/W2025184602","https://openalex.org/W2030628866","https://openalex.org/W2034673235","https://openalex.org/W2037950602","https://openalex.org/W2046851174","https://openalex.org/W2048238537","https://openalex.org/W2048789232","https://openalex.org/W2048810707","https://openalex.org/W2053175562","https://openalex.org/W2053229766","https://openalex.org/W2055837969","https://openalex.org/W2056164451","https://openalex.org/W2056222726","https://openalex.org/W2057410003","https://openalex.org/W2059576438","https://openalex.org/W2059587398","https://openalex.org/W2060605943","https://openalex.org/W2063658468","https://openalex.org/W2063915956","https://openalex.org/W2064077773","https://openalex.org/W2066074720","https://openalex.org/W2068616231","https://openalex.org/W2070650784","https://openalex.org/W2072295131","https://openalex.org/W2078278423","https://openalex.org/W2079579436","https://openalex.org/W2084187263","https://openalex.org/W2088259422","https://openalex.org/W2090568128","https://openalex.org/W2096364354","https://openalex.org/W2098286922","https://openalex.org/W2105764874","https://openalex.org/W2138458780","https://openalex.org/W2158202720","https://openalex.org/W2159218869","https://openalex.org/W2160357641","https://openalex.org/W2169401128","https://openalex.org/W2172138450","https://openalex.org/W2190516348","https://openalex.org/W2190806825","https://openalex.org/W2217712972","https://openalex.org/W2257702591","https://openalex.org/W2274692091","https://openalex.org/W2283044680","https://openalex.org/W2289042572","https://openalex.org/W2314259509","https://openalex.org/W2346582595","https://openalex.org/W2395639847","https://openalex.org/W2430880899","https://openalex.org/W2484957200","https://openalex.org/W2528405055","https://openalex.org/W2528767583","https://openalex.org/W2552540631","https://openalex.org/W2559764805","https://openalex.org/W2565004792","https://openalex.org/W2582527583","https://openalex.org/W2592375018","https://openalex.org/W2606250977","https://openalex.org/W2615896780","https://openalex.org/W2726617503","https://openalex.org/W2744366444","https://openalex.org/W2747729103","https://openalex.org/W2752800559","https://openalex.org/W2765174069","https://openalex.org/W2766621400","https://openalex.org/W2767076348","https://openalex.org/W2769956680","https://openalex.org/W2771196074","https://openalex.org/W2788268180","https://openalex.org/W2792481178","https://openalex.org/W2796453658","https://openalex.org/W2797704190","https://openalex.org/W2800255143","https://openalex.org/W2800980659","https://openalex.org/W2805772022","https://openalex.org/W2808328829","https://openalex.org/W2810100810","https://openalex.org/W2810109876","https://openalex.org/W2886783312","https://openalex.org/W2888431144","https://openalex.org/W2888899321","https://openalex.org/W2906674209","https://openalex.org/W2914224591","https://openalex.org/W2915588404","https://openalex.org/W2920490401","https://openalex.org/W2946440582","https://openalex.org/W2953463170","https://openalex.org/W2953930626","https://openalex.org/W4211209931","https://openalex.org/W4292542249"],"related_works":["https://openalex.org/W2146864995","https://openalex.org/W4313237059","https://openalex.org/W2077323385","https://openalex.org/W2392306680","https://openalex.org/W2918405227","https://openalex.org/W2095052940","https://openalex.org/W4283324873","https://openalex.org/W4307216241","https://openalex.org/W3093450845","https://openalex.org/W3108749156"],"abstract_inverted_index":{"Aptamers":[0,186],"are":[1,73,77,104,108],"synthetic":[2],"bio-receptors":[3],"of":[4,18,27,79,83,99,113,130,232],"deoxyribonucleic":[5],"acid":[6,10],"(DNA)":[7],"or":[8],"ribonucleic":[9],"(RNA)":[11],"origin":[12],"selected":[13],"by":[14],"the":[15,81,96,111,126,171,199,233,238],"systematic":[16],"evolution":[17],"ligands":[19],"(SELEX)":[20],"process":[21],"that":[22,139,221],"bind":[23],"a":[24,43,52,182,230],"broad":[25],"range":[26],"target":[28],"analytes":[29],"with":[30,178],"high":[31],"affinity":[32],"and":[33,45,66,69,91,118,167,206,227,251,254],"specificity.":[34],"So":[35],"far,":[36],"electrochemical":[37,102,136,215],"biosensors":[38,103],"have":[39,59,140,222,241,256],"come":[40],"up":[41],"as":[42,51,181,229],"simple":[44],"sensitive":[46],"method":[47],"to":[48,124,176],"utilize":[49],"aptamers":[50,172,240],"bio-recognition":[53],"element.":[54],"Numerous":[55],"aptamer":[56,100,134,216],"based":[57,101,135,217],"sensors":[58,156],"been":[60,141,223,242,257],"developed":[61,142],"for":[62,161,245],"clinical":[63,88,116,207],"diagnostics,":[64,89],"food,":[65,90,204],"environmental":[67,92],"monitoring":[68],"several":[70],"other":[71],"applications":[72,98,107],"under":[74],"development.":[75],"Aptasensors":[76],"capable":[78],"extending":[80],"limits":[82],"current":[84,106,152],"analytical":[85],"techniques":[86],"in":[87,110,133,143,190,237,260],"sample":[93],"analysis.":[94],"However,":[95],"potential":[97],"unlimited;":[105],"observed":[109],"areas":[112],"food":[114],"toxins,":[115],"biomarkers,":[117,164],"pesticide":[119],"detection.":[120],"This":[121,210],"review":[122,211],"attempts":[123],"enumerate":[125],"most":[127],"representative":[128],"examples":[129],"research":[131],"progress":[132],"biosensing":[137],"principles":[138],"recent":[144,200],"years.":[145],"Additionally,":[146],"this":[147,194,261],"account":[148,195],"will":[149,196],"discuss":[150],"various":[151,162,191,214],"developments":[153],"on":[154,169,198],"aptamer-based":[155],"toward":[157,203],"heavy":[158],"metal":[159],"detection,":[160,166],"cardiac":[163],"antibiotics":[165],"also":[168],"how":[170],"can":[173,187],"be":[174,188],"deployed":[175],"couple":[177],"antibody-based":[179],"assays":[180],"hybrid":[183],"sensing":[184],"platform.":[185],"used":[189,228],"applications,":[192],"however,":[193],"focus":[197],"advancements":[201],"made":[202],"environmental,":[205,246],"diagnostic":[208],"application.":[209],"paper":[212],"compares":[213],"sensor":[218],"detection":[219,253],"strategies":[220],"applied":[224],"so":[225],"far":[226],"state":[231],"art.":[234],"As":[235],"illustrated":[236],"literature,":[239],"utilized":[243],"extensively":[244,258],"cancer":[247],"biomarker,":[248],"biomedical":[249],"application,":[250],"antibiotic":[252],"thus":[255],"discussed":[259],"article.":[262]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":22},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":25},{"year":2020,"cited_by_count":10}],"updated_date":"2026-03-31T07:56:22.981413","created_date":"2025-10-10T00:00:00"}