{"id":"https://openalex.org/W2900636560","doi":"https://doi.org/10.3390/s18114011","title":"A Novel Microfluidic Point-of-Care Biosensor System on Printed Circuit Board for Cytokine Detection","display_name":"A Novel Microfluidic Point-of-Care Biosensor System on Printed Circuit Board for Cytokine Detection","publication_year":2018,"publication_date":"2018-11-17","ids":{"openalex":"https://openalex.org/W2900636560","doi":"https://doi.org/10.3390/s18114011","mag":"2900636560","pmid":"https://pubmed.ncbi.nlm.nih.gov/30453609"},"language":"en","primary_location":{"id":"doi:10.3390/s18114011","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s18114011","pdf_url":"https://www.mdpi.com/1424-8220/18/11/4011/pdf?version=1542606900","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/18/11/4011/pdf?version=1542606900","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102934731","display_name":"Daniel A. Evans","orcid":"https://orcid.org/0000-0002-0536-6488"},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Daniel Evans","raw_affiliation_strings":["Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062507822","display_name":"Konstantinos I. Papadimitriou","orcid":"https://orcid.org/0000-0002-0995-4834"},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Konstantinos Papadimitriou","raw_affiliation_strings":["Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK"],"raw_orcid":"https://orcid.org/0000-0002-0995-4834","affiliations":[{"raw_affiliation_string":"Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054655542","display_name":"Nikolaos Vasilakis","orcid":null},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nikolaos Vasilakis","raw_affiliation_strings":["Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063808747","display_name":"Panagiotis Pantelidis","orcid":"https://orcid.org/0000-0002-3111-601X"},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]},{"id":"https://openalex.org/I4210108386","display_name":"North West London Pathology","ror":"https://ror.org/01jap5s81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210108386"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Panagiotis Pantelidis","raw_affiliation_strings":["Centre for Immunology and Vaccinology, Division of Infectious Diseases, Department of Medicine, Imperial College London, London SW10 9NH, UK","Infection and Immunity, North West London Pathology, Imperial College NHS Trust, Charing Cross Hospital, London W6 8RF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Immunology and Vaccinology, Division of Infectious Diseases, Department of Medicine, Imperial College London, London SW10 9NH, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Infection and Immunity, North West London Pathology, Imperial College NHS Trust, Charing Cross Hospital, London W6 8RF, UK","institution_ids":["https://openalex.org/I2802369498","https://openalex.org/I4210108386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065105169","display_name":"Peter Kelleher","orcid":null},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]},{"id":"https://openalex.org/I4210108386","display_name":"North West London Pathology","ror":"https://ror.org/01jap5s81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210108386"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter Kelleher","raw_affiliation_strings":["Centre for Immunology and Vaccinology, Division of Infectious Diseases, Department of Medicine, Imperial College London, London SW10 9NH, UK","Infection and Immunity, North West London Pathology, Imperial College NHS Trust, Charing Cross Hospital, London W6 8RF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Immunology and Vaccinology, Division of Infectious Diseases, Department of Medicine, Imperial College London, London SW10 9NH, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Infection and Immunity, North West London Pathology, Imperial College NHS Trust, Charing Cross Hospital, London W6 8RF, UK","institution_ids":["https://openalex.org/I2802369498","https://openalex.org/I4210108386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057219162","display_name":"Hywel Morgan","orcid":"https://orcid.org/0000-0003-4850-5676"},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hywel Morgan","raw_affiliation_strings":["Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK","Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"Nanoelectronics & Nanotechnology Research Group, Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088089733","display_name":"Themis Prodromakis","orcid":"https://orcid.org/0000-0002-6267-6909"},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Themistoklis Prodromakis","raw_affiliation_strings":["Zepler Institute for Photonics and Nanoelectronics, University of Southampton, Southampton SO17 1BJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zepler Institute for Photonics and Nanoelectronics, University of Southampton, Southampton SO17 1BJ, UK","institution_ids":["https://openalex.org/I43439940"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5102934731"],"corresponding_institution_ids":["https://openalex.org/I43439940"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2673},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2673},"fwci":2.3041,"has_fulltext":true,"cited_by_count":56,"citation_normalized_percentile":{"value":0.88476033,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"18","issue":"11","first_page":"4011","last_page":"4011"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.8619915246963501},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.6550673246383667},{"id":"https://openalex.org/keywords/amperometry","display_name":"Amperometry","score":0.5961264371871948},{"id":"https://openalex.org/keywords/reference-electrode","display_name":"Reference electrode","score":0.5465145707130432},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5112171173095703},{"id":"https://openalex.org/keywords/printed-circuit-board","display_name":"Printed circuit board","score":0.5009162425994873},{"id":"https://openalex.org/keywords/point-of-care","display_name":"Point of care","score":0.4878814220428467},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.4425315856933594},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.40186846256256104},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.33936822414398193},{"id":"https://openalex.org/keywords/electrochemistry","display_name":"Electrochemistry","score":0.23357897996902466},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.11262774467468262},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.10589101910591125}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.8619915246963501},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.6550673246383667},{"id":"https://openalex.org/C139369640","wikidata":"https://www.wikidata.org/wiki/Q474536","display_name":"Amperometry","level":4,"score":0.5961264371871948},{"id":"https://openalex.org/C40290423","wikidata":"https://www.wikidata.org/wiki/Q653954","display_name":"Reference electrode","level":4,"score":0.5465145707130432},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5112171173095703},{"id":"https://openalex.org/C120793396","wikidata":"https://www.wikidata.org/wiki/Q173350","display_name":"Printed circuit board","level":2,"score":0.5009162425994873},{"id":"https://openalex.org/C51915194","wikidata":"https://www.wikidata.org/wiki/Q17075487","display_name":"Point of care","level":2,"score":0.4878814220428467},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.4425315856933594},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.40186846256256104},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33936822414398193},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.23357897996902466},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.11262774467468262},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10589101910591125},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019095","descriptor_name":"Point-of-Care Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019095","descriptor_name":"Point-of-Care Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019095","descriptor_name":"Point-of-Care Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057230","descriptor_name":"Limit of Detection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057230","descriptor_name":"Limit of Detection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057230","descriptor_name":"Limit of Detection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.3390/s18114011","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s18114011","pdf_url":"https://www.mdpi.com/1424-8220/18/11/4011/pdf?version=1542606900","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:30453609","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30453609","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:eprints.soton.ac.uk:426646","is_oa":true,"landing_page_url":null,"pdf_url":"https://eprints.soton.ac.uk/426646/1/sensors_18_04011_v2.pdf","source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:47106096d4514be5bf1f673b7b250f7f","is_oa":true,"landing_page_url":"https://doaj.org/article/47106096d4514be5bf1f673b7b250f7f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 18, Iss 11, p 4011 (2018)","raw_type":"article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10062569","is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10062569/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors , 18 (11) (2018)","raw_type":"Article"},{"id":"pmh:oai:europepmc.org:5257959","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6264023","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:mdpi.com:/1424-8220/18/11/4011/","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/s18114011","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6264023","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6264023","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors (Basel)","raw_type":"Text"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/65411","is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/65411","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/s18114011","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s18114011","pdf_url":"https://www.mdpi.com/1424-8220/18/11/4011/pdf?version=1542606900","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4167466092","display_name":null,"funder_award_id":"EP/L020920/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8951151108","display_name":"An electronic-based ELISA combined with microfluidics","funder_award_id":"EP/L020920/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320322381","display_name":"A.G. Leventis Foundation","ror":null},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2900636560.pdf","grobid_xml":"https://content.openalex.org/works/W2900636560.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W1482474103","https://openalex.org/W1806464343","https://openalex.org/W1898049656","https://openalex.org/W1964600478","https://openalex.org/W1968263951","https://openalex.org/W1985186092","https://openalex.org/W1989437429","https://openalex.org/W1992189573","https://openalex.org/W2016681264","https://openalex.org/W2022570095","https://openalex.org/W2035556428","https://openalex.org/W2050604127","https://openalex.org/W2076358580","https://openalex.org/W2076958395","https://openalex.org/W2081270882","https://openalex.org/W2085559524","https://openalex.org/W2088383477","https://openalex.org/W2090983970","https://openalex.org/W2091444562","https://openalex.org/W2095363155","https://openalex.org/W2119188897","https://openalex.org/W2130329278","https://openalex.org/W2159773654","https://openalex.org/W2165066473","https://openalex.org/W2175780827","https://openalex.org/W2200433758","https://openalex.org/W2258647344","https://openalex.org/W2275832075","https://openalex.org/W2339134062","https://openalex.org/W2395889732","https://openalex.org/W2400828421","https://openalex.org/W2402076654","https://openalex.org/W2471127784","https://openalex.org/W2477146923","https://openalex.org/W2514354410","https://openalex.org/W2560226454","https://openalex.org/W2562996961","https://openalex.org/W2567220511","https://openalex.org/W2573619499","https://openalex.org/W2581576631","https://openalex.org/W2585231644","https://openalex.org/W2592298146","https://openalex.org/W2592615709","https://openalex.org/W2598860043","https://openalex.org/W2602359960","https://openalex.org/W2608617863","https://openalex.org/W2616537033","https://openalex.org/W2617939011","https://openalex.org/W2620798947","https://openalex.org/W2735534200","https://openalex.org/W2736939718","https://openalex.org/W2754083006","https://openalex.org/W2757721278","https://openalex.org/W2767005164","https://openalex.org/W2770448154","https://openalex.org/W2787680782","https://openalex.org/W2789452602","https://openalex.org/W2804637298","https://openalex.org/W2889699668","https://openalex.org/W2890013995","https://openalex.org/W2895599817","https://openalex.org/W2915766653","https://openalex.org/W2921648826","https://openalex.org/W2964340629"],"related_works":["https://openalex.org/W135239450","https://openalex.org/W3217489758","https://openalex.org/W2006985190","https://openalex.org/W2262254151","https://openalex.org/W3157217153","https://openalex.org/W2066987080","https://openalex.org/W1024889183","https://openalex.org/W2072907890","https://openalex.org/W1994064849","https://openalex.org/W1992310753"],"abstract_inverted_index":{"Point":[0],"of":[1,9,133,151,175,185,191],"Care":[2],"(PoC)":[3],"diagnostics":[4],"have":[5],"been":[6,117],"the":[7,13,19,130,134,164,183],"subject":[8],"considerable":[10],"research":[11],"over":[12],"last":[14],"few":[15],"decades":[16],"driven":[17],"by":[18,156],"pressure":[20],"to":[21,64,87,123,139,178],"detect":[22],"diseases":[23],"quickly":[24],"and":[25,27,97,100,142,145,170,172],"effectively":[26],"reduce":[28],"healthcare":[29],"costs.":[30],"Herein,":[31],"we":[32,147,162],"demonstrate":[33,173],"a":[34,46,54,75,101],"novel,":[35],"fully":[36],"integrated,":[37],"microfluidic":[38,93,120,187],"amperometric":[39],"enzyme-linked":[40],"immunosorbent":[41],"assay":[42,51,60,72,83,165,188],"(ELISA)":[43],"prototype":[44],"using":[45],"commercial":[47,110,180],"interferon":[48],"gamma":[49],"release":[50],"(IGRA)":[52],"as":[53,154],"model":[55],"antibody":[56],"binding":[57],"system.":[58,81],"Microfluidic":[59],"chemistry":[61,115],"was":[62],"engineered":[63],"take":[65],"place":[66],"on":[67,74],"Au-plated":[68],"electrodes":[69,99],"within":[70],"an":[71,88],"cell":[73,84,91],"printed":[76],"circuit":[77],"board":[78],"(PCB)-based":[79],"biosensor":[80],"The":[82],"is":[85],"linked":[86],"electrochemical":[89],"reporter":[90],"comprising":[92],"architecture,":[94],"Au":[95],"working":[96],"counter":[98],"Ag/AgCl":[102],"reference":[103,138],"electrode,":[104],"all":[105],"manufactured":[106],"exclusively":[107],"via":[108],"standard":[109],"PCB":[111],"fabrication":[112],"processes.":[113],"Assay":[114],"has":[116],"optimised":[118],"for":[119],"diffusion":[121],"kinetics":[122],"function":[124],"under":[125],"continual":[126],"flow.":[127],"We":[128],"characterised":[129],"electrode":[131],"integrity":[132],"developed":[135],"platforms":[136],"with":[137,182],"biological":[140],"sampling":[141],"buffer":[143,169],"composition":[144],"subsequently":[146],"demonstrated":[148],"concentration-dependent":[149],"measurements":[150],"H\u2082O\u2082":[152],"depletion":[153],"resolved":[155],"existing":[157],"FDA-validated":[158],"ELISA":[159],"kits.":[160],"Finally,":[161],"validated":[163],"technology":[166],"in":[167,195],"both":[168],"serum":[171],"limits":[174],"detection":[176],"comparable":[177],"high-end":[179],"systems":[181],"addition":[184],"full":[186],"architecture":[189],"capable":[190],"returning":[192],"diagnostic":[193],"analyses":[194],"approximately":[196],"eight":[197],"minutes.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}