{"id":"https://openalex.org/W2791842289","doi":"https://doi.org/10.3390/s18030686","title":"An Amperometric Biosensor for the Determination of Bacterial Sepsis Biomarker, Secretory Phospholipase Group 2-IIA Using a Tri-Enzyme System","display_name":"An Amperometric Biosensor for the Determination of Bacterial Sepsis Biomarker, Secretory Phospholipase Group 2-IIA Using a Tri-Enzyme System","publication_year":2018,"publication_date":"2018-02-26","ids":{"openalex":"https://openalex.org/W2791842289","doi":"https://doi.org/10.3390/s18030686","mag":"2791842289","pmid":"https://pubmed.ncbi.nlm.nih.gov/29495352"},"language":"en","primary_location":{"id":"doi:10.3390/s18030686","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s18030686","pdf_url":"https://www.mdpi.com/1424-8220/18/3/686/pdf?version=1519618598","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/18/3/686/pdf?version=1519618598","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103798957","display_name":"Nik Nik Mansor","orcid":null},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Nik Nik Mansor","raw_affiliation_strings":["School of Chemical Sciences and Food Technology, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor DE, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Sciences and Food Technology, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor DE, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tan Leong","orcid":null},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Tan Leong","raw_affiliation_strings":["Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034471069","display_name":"Eka Safitri","orcid":"https://orcid.org/0000-0002-8023-3095"},"institutions":[{"id":"https://openalex.org/I187494767","display_name":"Universitas Syiah Kuala","ror":"https://ror.org/05v4dza81","country_code":"ID","type":"education","lineage":["https://openalex.org/I187494767"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Eka Safitri","raw_affiliation_strings":["Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala University (USK), Darussalam-Banda Acheh 23111, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala University (USK), Darussalam-Banda Acheh 23111, Indonesia","institution_ids":["https://openalex.org/I187494767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016610033","display_name":"Dedi Futra","orcid":"https://orcid.org/0000-0001-5707-587X"},"institutions":[{"id":"https://openalex.org/I92961808","display_name":"Riau University","ror":"https://ror.org/00nk7p507","country_code":"ID","type":"education","lineage":["https://openalex.org/I92961808"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Dedi Futra","raw_affiliation_strings":["The Department of Chemistry Education, Faculty of Education, Universitas Riau, Kampus Binawidya KM 12.5, Pekanbaru 28293, Riau, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Chemistry Education, Faculty of Education, Universitas Riau, Kampus Binawidya KM 12.5, Pekanbaru 28293, Riau, Indonesia","institution_ids":["https://openalex.org/I92961808"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062257828","display_name":"Nurul Saadah Ahmad","orcid":"https://orcid.org/0000-0002-1032-4004"},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Nurul Ahmad","raw_affiliation_strings":["Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046771088","display_name":"Dian Nasriana Nasuruddin","orcid":null},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Dian Nasuruddin","raw_affiliation_strings":["Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058490376","display_name":"Azlin Itnin","orcid":null},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Azlin Itnin","raw_affiliation_strings":["Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001220628","display_name":"Ida Zarina Zaini","orcid":"https://orcid.org/0000-0003-0127-8453"},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Ida Zaini","raw_affiliation_strings":["Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006327517","display_name":"Khaizurin Tajul Arifin","orcid":null},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Khaizurin Arifin","raw_affiliation_strings":["Department of Biochemistry Education, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry Education, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031383187","display_name":"Lee Yook Heng","orcid":"https://orcid.org/0000-0001-9843-9182"},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Lee Heng","raw_affiliation_strings":["School of Chemical Sciences and Food Technology, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor DE, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Sciences and Food Technology, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor DE, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013161753","display_name":"Nurul Izzaty Hassan","orcid":"https://orcid.org/0000-0002-1235-4290"},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Nurul Hassan","raw_affiliation_strings":["School of Chemical Sciences and Food Technology, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor DE, Malaysia"],"raw_orcid":"https://orcid.org/0000-0002-1235-4290","affiliations":[{"raw_affiliation_string":"School of Chemical Sciences and Food Technology, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor DE, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5013161753"],"corresponding_institution_ids":["https://openalex.org/I885383172"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":1.6696,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.84123015,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"18","issue":"3","first_page":"686","last_page":"686"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9921000003814697,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.9751999974250793,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.7373329401016235},{"id":"https://openalex.org/keywords/amperometry","display_name":"Amperometry","score":0.7008501887321472},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.6311466097831726},{"id":"https://openalex.org/keywords/enzyme","display_name":"Enzyme","score":0.5553834438323975},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.545192301273346},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5081374645233154},{"id":"https://openalex.org/keywords/sepsis","display_name":"Sepsis","score":0.46171805262565613},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.43809300661087036},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.4235409200191498},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2925828695297241},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28274765610694885},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.16586920619010925},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.0884767472743988}],"concepts":[{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.7373329401016235},{"id":"https://openalex.org/C139369640","wikidata":"https://www.wikidata.org/wiki/Q474536","display_name":"Amperometry","level":4,"score":0.7008501887321472},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6311466097831726},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5553834438323975},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.545192301273346},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5081374645233154},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.46171805262565613},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.43809300661087036},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4235409200191498},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2925828695297241},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28274765610694885},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16586920619010925},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.0884767472743988},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004800","descriptor_name":"Enzymes, Immobilized","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004800","descriptor_name":"Enzymes, Immobilized","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004800","descriptor_name":"Enzymes, Immobilized","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010740","descriptor_name":"Phospholipases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010740","descriptor_name":"Phospholipases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010740","descriptor_name":"Phospholipases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/s18030686","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s18030686","pdf_url":"https://www.mdpi.com/1424-8220/18/3/686/pdf?version=1519618598","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:29495352","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29495352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:d82ca240e58f4e6eb6f1e7033bf70eef","is_oa":true,"landing_page_url":"https://doaj.org/article/d82ca240e58f4e6eb6f1e7033bf70eef","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 18, Iss 3, p 686 (2018)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4796755","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5876737","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:mdpi.com:/1424-8220/18/3/686/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s18030686","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 18; Issue 3; Pages: 686","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s18030686","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s18030686","pdf_url":"https://www.mdpi.com/1424-8220/18/3/686/pdf?version=1519618598","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3254630434","display_name":null,"funder_award_id":"GP-5179","funder_id":"https://openalex.org/F4320322699","funder_display_name":"Universiti Kebangsaan Malaysia"},{"id":"https://openalex.org/G5050206968","display_name":null,"funder_award_id":"ETP-2013-050","funder_id":"https://openalex.org/F4320322699","funder_display_name":"Universiti Kebangsaan Malaysia"},{"id":"https://openalex.org/G6451650262","display_name":null,"funder_award_id":"GP-5179-2017","funder_id":"https://openalex.org/F4320322699","funder_display_name":"Universiti Kebangsaan Malaysia"},{"id":"https://openalex.org/G6871245582","display_name":null,"funder_award_id":"GUP-2016-059","funder_id":"https://openalex.org/F4320322699","funder_display_name":"Universiti Kebangsaan Malaysia"}],"funders":[{"id":"https://openalex.org/F4320322699","display_name":"Universiti Kebangsaan Malaysia","ror":"https://ror.org/00bw8d226"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2791842289.pdf","grobid_xml":"https://content.openalex.org/works/W2791842289.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W285430858","https://openalex.org/W563007011","https://openalex.org/W1972809036","https://openalex.org/W1973468590","https://openalex.org/W1976390848","https://openalex.org/W1977332525","https://openalex.org/W1986858178","https://openalex.org/W2012618796","https://openalex.org/W2014726627","https://openalex.org/W2034261692","https://openalex.org/W2070450550","https://openalex.org/W2121983438","https://openalex.org/W2127774299","https://openalex.org/W2132331468","https://openalex.org/W2143472088","https://openalex.org/W2145130641","https://openalex.org/W2150038091","https://openalex.org/W2156722088","https://openalex.org/W2172250133","https://openalex.org/W2310361142","https://openalex.org/W2330401456","https://openalex.org/W2400856821","https://openalex.org/W2533022902","https://openalex.org/W2732587388","https://openalex.org/W2768146862","https://openalex.org/W6615713025"],"related_works":["https://openalex.org/W135239450","https://openalex.org/W2046430340","https://openalex.org/W2383021773","https://openalex.org/W2322026400","https://openalex.org/W4206515393","https://openalex.org/W1990396141","https://openalex.org/W1929958295","https://openalex.org/W2226641048","https://openalex.org/W2145252373","https://openalex.org/W2080565361"],"abstract_inverted_index":{"A":[0],"tri-enzyme":[1,62],"system":[2,63],"consisting":[3],"of":[4,17,44,50,70,81,118,155,169,175],"choline":[5],"kinase/choline":[6],"oxidase/horseradish":[7],"peroxidase":[8],"was":[9,75,106,112,163],"used":[10],"in":[11,60,192],"the":[12,18,35,42,61,67,78,109,146,183],"rapid":[13,188],"and":[14,94,108],"specific":[15],"determination":[16],"biomarker":[19],"for":[20,41,179,187],"bacterial":[21,189],"sepsis":[22,190],"infection,":[23],"secretory":[24],"phospholipase":[25],"Group":[26],"2-IIA":[27],"(sPLA2-IIA).":[28],"These":[29],"enzymes":[30],"were":[31],"individually":[32],"immobilized":[33],"onto":[34,99],"acrylic":[36,92],"microspheres":[37,93],"via":[38],"succinimide":[39],"groups":[40],"preparation":[43],"an":[45],"electrochemical":[46],"biosensor.":[47],"The":[48,160],"reaction":[49,59],"sPLA2-IIA":[51,180],"with":[52,133],"its":[53],"substrate":[54],"initiated":[55],"a":[56,100,115,125,134],"cascading":[57],"enzymatic":[58,122],"that":[64,182],"led":[65],"to":[66,166],"final":[68],"production":[69],"hydrogen":[71],"peroxide,":[72],"which":[73],"presence":[74],"indicated":[76,181],"by":[77],"redox":[79],"characteristics":[80],"potassium":[82],"ferricyanide,":[83],"K3Fe(CN)6.":[84],"An":[85],"amperometric":[86],"biosensor":[87,123,147,161,184],"based":[88],"on":[89],"enzyme":[90],"conjugated":[91],"gold":[95],"nanoparticles":[96],"composite":[97],"coated":[98],"carbon-paste":[101],"screen":[102],"printed":[103],"electrode":[104],"(SPE)":[105],"fabricated":[107],"current":[110],"measurement":[111],"performed":[113],"at":[114,138,171],"low":[116],"potential":[117,186],"0.20":[119],"V.":[120],"This":[121],"gave":[124],"linear":[126],"range":[127],"0.01\u2013100":[128],"ng/mL":[129,142],"(R2":[130],"=":[131,158],"0.98304)":[132],"detection":[135],"limit":[136],"recorded":[137],"5":[139],"\u00d7":[140],"10\u22123":[141],"towards":[143],"sPLA2-IIA.":[144],"Moreover,":[145],"showed":[148],"good":[149],"reproducibility":[150],"(relative":[151],"standard":[152],"deviation":[153],"(RSD)":[154],"3.04%":[156],"(n":[157],"5).":[159],"response":[162],"reliable":[164],"up":[165],"25":[167],"days":[168],"storage":[170],"4":[172],"\u00b0C.":[173],"Analysis":[174],"human":[176],"serum":[177],"samples":[178],"has":[185],"diagnosis":[191],"hospital":[193],"emergency":[194],"department.":[195]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":4}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2018-03-29T00:00:00"}