{"id":"https://openalex.org/W2735130713","doi":"https://doi.org/10.3390/s17071630","title":"A Label-Free Fluorescent Array Sensor Utilizing Liposome Encapsulating Calcein for Discriminating Target Proteins by Principal Component Analysis","display_name":"A Label-Free Fluorescent Array Sensor Utilizing Liposome Encapsulating Calcein for Discriminating Target Proteins by Principal Component Analysis","publication_year":2017,"publication_date":"2017-07-15","ids":{"openalex":"https://openalex.org/W2735130713","doi":"https://doi.org/10.3390/s17071630","mag":"2735130713","pmid":"https://pubmed.ncbi.nlm.nih.gov/28714873"},"language":"en","primary_location":{"id":"doi:10.3390/s17071630","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s17071630","pdf_url":"https://www.mdpi.com/1424-8220/17/7/1630/pdf?version=1500104462","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/17/7/1630/pdf?version=1500104462","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113711257","display_name":"Ryota Imamura","orcid":null},"institutions":[{"id":"https://openalex.org/I27429435","display_name":"Kyoto Institute of Technology","ror":"https://ror.org/00965ax52","country_code":"JP","type":"education","lineage":["https://openalex.org/I27429435"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryota Imamura","raw_affiliation_strings":["Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan","institution_ids":["https://openalex.org/I27429435"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031225419","display_name":"Naoki Murata","orcid":"https://orcid.org/0000-0001-7418-5173"},"institutions":[{"id":"https://openalex.org/I27429435","display_name":"Kyoto Institute of Technology","ror":"https://ror.org/00965ax52","country_code":"JP","type":"education","lineage":["https://openalex.org/I27429435"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoki Murata","raw_affiliation_strings":["Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan","institution_ids":["https://openalex.org/I27429435"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035434445","display_name":"Toshinori Shimanouchi","orcid":"https://orcid.org/0000-0002-3382-0254"},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshinori Shimanouchi","raw_affiliation_strings":["Graduate School of Environmental and Life Science, Okayama University, 1-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Environmental and Life Science, Okayama University, 1-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101636779","display_name":"Kaoru Yamashita","orcid":"https://orcid.org/0000-0001-7922-8275"},"institutions":[{"id":"https://openalex.org/I27429435","display_name":"Kyoto Institute of Technology","ror":"https://ror.org/00965ax52","country_code":"JP","type":"education","lineage":["https://openalex.org/I27429435"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaoru Yamashita","raw_affiliation_strings":["Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan","institution_ids":["https://openalex.org/I27429435"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034208174","display_name":"Masayuki Fukuzawa","orcid":"https://orcid.org/0000-0002-6457-3233"},"institutions":[{"id":"https://openalex.org/I27429435","display_name":"Kyoto Institute of Technology","ror":"https://ror.org/00965ax52","country_code":"JP","type":"education","lineage":["https://openalex.org/I27429435"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masayuki Fukuzawa","raw_affiliation_strings":["Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan","institution_ids":["https://openalex.org/I27429435"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101609984","display_name":"Minoru Noda","orcid":"https://orcid.org/0000-0002-9780-996X"},"institutions":[{"id":"https://openalex.org/I27429435","display_name":"Kyoto Institute of Technology","ror":"https://ror.org/00965ax52","country_code":"JP","type":"education","lineage":["https://openalex.org/I27429435"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Minoru Noda","raw_affiliation_strings":["Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan","institution_ids":["https://openalex.org/I27429435"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101609984"],"corresponding_institution_ids":["https://openalex.org/I27429435"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":1.6668,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.8251091,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"17","issue":"7","first_page":"1630","last_page":"1630"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.8779428005218506},{"id":"https://openalex.org/keywords/liposome","display_name":"Liposome","score":0.6848571300506592},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5539379715919495},{"id":"https://openalex.org/keywords/membrane","display_name":"Membrane","score":0.5500255823135376},{"id":"https://openalex.org/keywords/sensor-array","display_name":"Sensor array","score":0.5263948440551758},{"id":"https://openalex.org/keywords/fluorophore","display_name":"Fluorophore","score":0.5141089558601379},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.4790010154247284},{"id":"https://openalex.org/keywords/principal-component-analysis","display_name":"Principal component analysis","score":0.44326502084732056},{"id":"https://openalex.org/keywords/calcein","display_name":"Calcein","score":0.4424678087234497},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.43631595373153687},{"id":"https://openalex.org/keywords/phospholipid","display_name":"Phospholipid","score":0.41789793968200684},{"id":"https://openalex.org/keywords/analytical-chemistry","display_name":"Analytical Chemistry (journal)","score":0.38452455401420593},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.322053998708725},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2007129192352295},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1273452639579773},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.09740898013114929},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.07029742002487183}],"concepts":[{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.8779428005218506},{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.6848571300506592},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5539379715919495},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5500255823135376},{"id":"https://openalex.org/C66251956","wikidata":"https://www.wikidata.org/wiki/Q7451086","display_name":"Sensor array","level":2,"score":0.5263948440551758},{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.5141089558601379},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.4790010154247284},{"id":"https://openalex.org/C27438332","wikidata":"https://www.wikidata.org/wiki/Q2873","display_name":"Principal component analysis","level":2,"score":0.44326502084732056},{"id":"https://openalex.org/C2776872141","wikidata":"https://www.wikidata.org/wiki/Q413006","display_name":"Calcein","level":3,"score":0.4424678087234497},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.43631595373153687},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.41789793968200684},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.38452455401420593},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.322053998708725},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2007129192352295},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1273452639579773},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.09740898013114929},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.07029742002487183},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005452","descriptor_name":"Fluoresceins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005452","descriptor_name":"Fluoresceins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005452","descriptor_name":"Fluoresceins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005452","descriptor_name":"Fluoresceins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.3390/s17071630","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s17071630","pdf_url":"https://www.mdpi.com/1424-8220/17/7/1630/pdf?version=1500104462","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:28714873","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28714873","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:af491d1a3eee4c1ba6dfd661da95b9f2","is_oa":true,"landing_page_url":"https://doaj.org/article/af491d1a3eee4c1ba6dfd661da95b9f2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 17, Iss 7, p 1630 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4394309","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5539792","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:mdpi.com:/1424-8220/17/7/1630/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s17071630","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 17; Issue 7; Pages: 1630","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s17071630","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s17071630","pdf_url":"https://www.mdpi.com/1424-8220/17/7/1630/pdf?version=1500104462","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7599999904632568,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[{"id":"https://openalex.org/G3070003065","display_name":null,"funder_award_id":"25249048","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7872078826","display_name":null,"funder_award_id":"26630157","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2735130713.pdf","grobid_xml":"https://content.openalex.org/works/W2735130713.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W418034114","https://openalex.org/W1533462164","https://openalex.org/W1963681945","https://openalex.org/W1973216210","https://openalex.org/W1984974677","https://openalex.org/W1988093242","https://openalex.org/W1988728360","https://openalex.org/W1990597901","https://openalex.org/W1993417488","https://openalex.org/W2005485852","https://openalex.org/W2020659177","https://openalex.org/W2028765521","https://openalex.org/W2039987993","https://openalex.org/W2042373158","https://openalex.org/W2068055698","https://openalex.org/W2077087610","https://openalex.org/W2078121948","https://openalex.org/W2079545013","https://openalex.org/W2084465048","https://openalex.org/W2085699964","https://openalex.org/W2086054287","https://openalex.org/W2088880611","https://openalex.org/W2089976313","https://openalex.org/W2128040385","https://openalex.org/W2130529613","https://openalex.org/W2142504461","https://openalex.org/W2143437376","https://openalex.org/W2153049318","https://openalex.org/W2160770509","https://openalex.org/W2177969558","https://openalex.org/W2586983804","https://openalex.org/W2599548809","https://openalex.org/W3155973889","https://openalex.org/W4254470479","https://openalex.org/W4296424065","https://openalex.org/W6651892842","https://openalex.org/W6680885894","https://openalex.org/W6733644132","https://openalex.org/W6793842060"],"related_works":["https://openalex.org/W2754131735","https://openalex.org/W2025441926","https://openalex.org/W2101132035","https://openalex.org/W2969136920","https://openalex.org/W2247479559","https://openalex.org/W3164665447","https://openalex.org/W13190771","https://openalex.org/W3092297591","https://openalex.org/W2003731969","https://openalex.org/W2036919370"],"abstract_inverted_index":{"A":[0],"new":[1,47],"fluorescent":[2,24,32,49,58,78],"arrayed":[3],"biosensor":[4],"has":[5],"been":[6],"developed":[7,57],"to":[8,37,74],"discriminate":[9],"species":[10,22,137],"and":[11],"concentrations":[12,83,140],"of":[13,30,56,70,76,101,115,161,176],"target":[14],"proteins":[15],"by":[16,120,144,164],"using":[17,108,145],"plural":[18],"different":[19,135,147],"phospholipid":[20],"liposome":[21],"encapsulating":[23],"molecules,":[25],"utilizing":[26],"differences":[27],"in":[28],"permeation":[29],"the":[31,35,53,77,89,92,102,106,112,116,146,159,162,165],"molecules":[33,79],"through":[34,91],"membrane":[36],"modulate":[38],"liposome-target":[39],"protein":[40,136],"interactions.":[41],"This":[42],"approach":[43],"proposes":[44],"a":[45,66,109,121,169,177],"basically":[46],"label-free":[48],"sensor,":[50],"compared":[51],"with":[52,61,138,150,168,180],"common":[54],"technique":[55],"array":[59,99,166],"sensors":[60],"labeling.":[62],"We":[63,155],"have":[64],"confirmed":[65,157],"high":[67,151],"output":[68,113],"intensity":[69],"fluorescence":[71,103,117],"emission":[72,104],"related":[73],"characteristics":[75],"dependent":[80],"on":[81],"their":[82],"when":[84],"they":[85],"leak":[86],"from":[87,105,131],"inside":[88],"liposomes":[90],"perturbed":[93],"lipid":[94,148],"membrane.":[95],"After":[96],"taking":[97],"an":[98],"image":[100],"sensor":[107,167,179],"CMOS":[110],"imager,":[111],"intensities":[114],"were":[118,141],"analyzed":[119],"principal":[122],"component":[123],"analysis":[124],"(PCA)":[125],"statistical":[126],"method.":[127],"It":[128],"is":[129,172],"found":[130],"PCA":[132],"plots":[133],"that":[134,158,175],"several":[139],"successfully":[142],"discriminated":[143],"membranes":[149],"cumulative":[152],"contribution":[153],"ratio.":[154],"also":[156],"accuracy":[160],"discrimination":[163],"single":[170,178],"shot":[171],"higher":[173],"than":[174],"multiple":[181],"shots.":[182]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}