{"id":"https://openalex.org/W2620974652","doi":"https://doi.org/10.3390/s17061266","title":"Innovative High-Throughput SAXS Methodologies Based on Photonic Lab-on-a-Chip Sensors: Application to Macromolecular Studies","display_name":"Innovative High-Throughput SAXS Methodologies Based on Photonic Lab-on-a-Chip Sensors: Application to Macromolecular Studies","publication_year":2017,"publication_date":"2017-06-02","ids":{"openalex":"https://openalex.org/W2620974652","doi":"https://doi.org/10.3390/s17061266","mag":"2620974652","pmid":"https://pubmed.ncbi.nlm.nih.gov/28574461"},"language":"en","primary_location":{"id":"doi:10.3390/s17061266","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s17061266","pdf_url":"https://www.mdpi.com/1424-8220/17/6/1266/pdf?version=1496401633","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/17/6/1266/pdf?version=1496401633","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090642051","display_name":"Isaac Rodr\u00edguez-Ruiz","orcid":"https://orcid.org/0000-0003-3949-3888"},"institutions":[{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I4210127723","display_name":"Direction des Energies","ror":"https://ror.org/03cwzta72","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I4210127723"]},{"id":"https://openalex.org/I4210143636","display_name":"CEA Marcoule","ror":"https://ror.org/04140y156","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I4210143636"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Isaac Rodr\u00edguez-Ruiz","raw_affiliation_strings":["CEA, DEN, DMRC, SA2I, 30207 Bagnols-sur-Ce\u0300ze, France","CEA-DES (ex-DEN) - CEA-Direction des Energies (ex-Direction de l'Energie Nucl\u00e9aire) (France)"],"affiliations":[{"raw_affiliation_string":"CEA, DEN, DMRC, SA2I, 30207 Bagnols-sur-Ce\u0300ze, France","institution_ids":["https://openalex.org/I2738703131","https://openalex.org/I4210143636","https://openalex.org/I4210127723"]},{"raw_affiliation_string":"CEA-DES (ex-DEN) - CEA-Direction des Energies (ex-Direction de l'Energie Nucl\u00e9aire) (France)","institution_ids":["https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023094804","display_name":"Dimitri Radajewski","orcid":"https://orcid.org/0000-0003-0570-4050"},"institutions":[{"id":"https://openalex.org/I4210087602","display_name":"Laboratoire de G\u00e9nie Chimique","ror":"https://ror.org/003jnac13","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I205747304","https://openalex.org/I205747304","https://openalex.org/I205747304","https://openalex.org/I4210087602","https://openalex.org/I4210095849","https://openalex.org/I4210097961","https://openalex.org/I4210131653","https://openalex.org/I4405258862","https://openalex.org/I4405258862","https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Dimitri Radajewski","raw_affiliation_strings":["Laboratoire de G\u00e9nie Chimique, UMR 5503, 4 all\u00e9e Emile Monso, 31432 Toulouse, France","LGC - Laboratoire de G\u00e9nie Chimique (4 allee Emile Monso 31432 Toulouse  - France)"],"affiliations":[{"raw_affiliation_string":"Laboratoire de G\u00e9nie Chimique, UMR 5503, 4 all\u00e9e Emile Monso, 31432 Toulouse, France","institution_ids":["https://openalex.org/I4210087602"]},{"raw_affiliation_string":"LGC - Laboratoire de G\u00e9nie Chimique (4 allee Emile Monso 31432 Toulouse  - France)","institution_ids":["https://openalex.org/I4210087602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070311857","display_name":"Sophie Charton","orcid":"https://orcid.org/0000-0002-9594-4025"},"institutions":[{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I4210127723","display_name":"Direction des Energies","ror":"https://ror.org/03cwzta72","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I4210127723"]},{"id":"https://openalex.org/I4210143636","display_name":"CEA Marcoule","ror":"https://ror.org/04140y156","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I4210143636"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Charton","raw_affiliation_strings":["CEA, DEN, DMRC, SA2I, 30207 Bagnols-sur-Ce\u0300ze, France","CEA-DES (ex-DEN) - CEA-Direction des Energies (ex-Direction de l'Energie Nucl\u00e9aire) (France)"],"affiliations":[{"raw_affiliation_string":"CEA, DEN, DMRC, SA2I, 30207 Bagnols-sur-Ce\u0300ze, France","institution_ids":["https://openalex.org/I2738703131","https://openalex.org/I4210143636","https://openalex.org/I4210127723"]},{"raw_affiliation_string":"CEA-DES (ex-DEN) - CEA-Direction des Energies (ex-Direction de l'Energie Nucl\u00e9aire) (France)","institution_ids":["https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107705276","display_name":"Nhat Phamvan","orcid":null},"institutions":[{"id":"https://openalex.org/I4210087602","display_name":"Laboratoire de G\u00e9nie Chimique","ror":"https://ror.org/003jnac13","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I205747304","https://openalex.org/I205747304","https://openalex.org/I205747304","https://openalex.org/I4210087602","https://openalex.org/I4210095849","https://openalex.org/I4210097961","https://openalex.org/I4210131653","https://openalex.org/I4405258862","https://openalex.org/I4405258862","https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nhat Phamvan","raw_affiliation_strings":["Laboratoire de G\u00e9nie Chimique, UMR 5503, 4 all\u00e9e Emile Monso, 31432 Toulouse, France","LGC - Laboratoire de G\u00e9nie Chimique (4 allee Emile Monso 31432 Toulouse  - France)"],"affiliations":[{"raw_affiliation_string":"Laboratoire de G\u00e9nie Chimique, UMR 5503, 4 all\u00e9e Emile Monso, 31432 Toulouse, France","institution_ids":["https://openalex.org/I4210087602"]},{"raw_affiliation_string":"LGC - Laboratoire de G\u00e9nie Chimique (4 allee Emile Monso 31432 Toulouse  - France)","institution_ids":["https://openalex.org/I4210087602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034797922","display_name":"Martha Brennich","orcid":"https://orcid.org/0000-0003-0415-8334"},"institutions":[{"id":"https://openalex.org/I4210111092","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/01zjc6908","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210111092","https://openalex.org/I4210138560"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Martha Brennich","raw_affiliation_strings":["European Molecular Biology Laboratory, 71 avenue des Martyrs, 38000 Grenoble, France","EMBL - European Molecular Biology Laboratory [Grenoble] (71 avenue des Martyrs\r\nCS 90181\r\n38042 Grenoble Cedex 9 - France)"],"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, 71 avenue des Martyrs, 38000 Grenoble, France","institution_ids":["https://openalex.org/I4210111092"]},{"raw_affiliation_string":"EMBL - European Molecular Biology Laboratory [Grenoble] (71 avenue des Martyrs\r\nCS 90181\r\n38042 Grenoble Cedex 9 - France)","institution_ids":["https://openalex.org/I4210111092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102783315","display_name":"Petra Pernot","orcid":"https://orcid.org/0009-0004-9241-8195"},"institutions":[{"id":"https://openalex.org/I4210111092","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/01zjc6908","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210111092","https://openalex.org/I4210138560"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Petra Pernot","raw_affiliation_strings":["European Molecular Biology Laboratory, 71 avenue des Martyrs, 38000 Grenoble, France","EMBL - European Molecular Biology Laboratory [Grenoble] (71 avenue des Martyrs\r\nCS 90181\r\n38042 Grenoble Cedex 9 - France)"],"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, 71 avenue des Martyrs, 38000 Grenoble, France","institution_ids":["https://openalex.org/I4210111092"]},{"raw_affiliation_string":"EMBL - European Molecular Biology Laboratory [Grenoble] (71 avenue des Martyrs\r\nCS 90181\r\n38042 Grenoble Cedex 9 - France)","institution_ids":["https://openalex.org/I4210111092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083659848","display_name":"Fran\u00e7oise Bonnet\u00e9","orcid":null},"institutions":[{"id":"https://openalex.org/I198415970","display_name":"Universit\u00e9 d'Avignon et des Pays de Vaucluse","ror":"https://ror.org/00mfpxb84","country_code":"FR","type":"education","lineage":["https://openalex.org/I198415970"]},{"id":"https://openalex.org/I4210145258","display_name":"Institut des Biomol\u00e9cules Max Mousseron","ror":"https://ror.org/05d1e6v30","country_code":"FR","type":"facility","lineage":["https://openalex.org/I11935315","https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210128300","https://openalex.org/I4210145258"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fran\u00e7oise Bonnet\u00e9","raw_affiliation_strings":["Institut des Biomol\u00e9cules Max-Mousseron, UMR 5247, Universit\u00e9 d\u2019Avignon, 33 rue Louis Pasteur, 84000 Avignon, France","AU - Avignon Universit\u00e9 (74 rue Louis Pasteur - 84 029 Avignon cedex 1 - France)","IBMM - Institut des Biomol\u00e9cules Max Mousseron [P\u00f4le Chimie Balard] (Facult\u00e9 de Pharmacie - 15 Av. Charles Flahault - BP 14 491 - 34093 Montpellier Cedex 5 - France)"],"affiliations":[{"raw_affiliation_string":"Institut des Biomol\u00e9cules Max-Mousseron, UMR 5247, Universit\u00e9 d\u2019Avignon, 33 rue Louis Pasteur, 84000 Avignon, France","institution_ids":["https://openalex.org/I198415970","https://openalex.org/I4210145258"]},{"raw_affiliation_string":"AU - Avignon Universit\u00e9 (74 rue Louis Pasteur - 84 029 Avignon cedex 1 - France)","institution_ids":["https://openalex.org/I198415970"]},{"raw_affiliation_string":"IBMM - Institut des Biomol\u00e9cules Max Mousseron [P\u00f4le Chimie Balard] (Facult\u00e9 de Pharmacie - 15 Av. Charles Flahault - BP 14 491 - 34093 Montpellier Cedex 5 - France)","institution_ids":["https://openalex.org/I4210145258"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051447891","display_name":"S\u00e9bastien Teychen\u00e9","orcid":"https://orcid.org/0000-0002-4840-1829"},"institutions":[{"id":"https://openalex.org/I4210087602","display_name":"Laboratoire de G\u00e9nie Chimique","ror":"https://ror.org/003jnac13","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I205747304","https://openalex.org/I205747304","https://openalex.org/I205747304","https://openalex.org/I4210087602","https://openalex.org/I4210095849","https://openalex.org/I4210097961","https://openalex.org/I4210131653","https://openalex.org/I4405258862","https://openalex.org/I4405258862","https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S\u00e9bastien Teychen\u00e9","raw_affiliation_strings":["Laboratoire de G\u00e9nie Chimique, UMR 5503, 4 all\u00e9e Emile Monso, 31432 Toulouse, France","LGC - Laboratoire de G\u00e9nie Chimique (4 allee Emile Monso 31432 Toulouse  - France)"],"affiliations":[{"raw_affiliation_string":"Laboratoire de G\u00e9nie Chimique, UMR 5503, 4 all\u00e9e Emile Monso, 31432 Toulouse, France","institution_ids":["https://openalex.org/I4210087602"]},{"raw_affiliation_string":"LGC - Laboratoire de G\u00e9nie Chimique (4 allee Emile Monso 31432 Toulouse  - France)","institution_ids":["https://openalex.org/I4210087602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5090642051"],"corresponding_institution_ids":["https://openalex.org/I2738703131","https://openalex.org/I4210127723","https://openalex.org/I4210143636"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":1.5747,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.81836959,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"17","issue":"6","first_page":"1266","last_page":"1266"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9921000003814697,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/small-angle-x-ray-scattering","display_name":"Small-angle X-ray scattering","score":0.8272418975830078},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.5757282376289368},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5197003483772278},{"id":"https://openalex.org/keywords/radius-of-gyration","display_name":"Radius of gyration","score":0.5164592266082764},{"id":"https://openalex.org/keywords/throughput","display_name":"Throughput","score":0.4863177239894867},{"id":"https://openalex.org/keywords/gyration","display_name":"Gyration","score":0.47566670179367065},{"id":"https://openalex.org/keywords/synchrotron-radiation","display_name":"Synchrotron radiation","score":0.44508785009384155},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.4378138780593872},{"id":"https://openalex.org/keywords/scattering","display_name":"Scattering","score":0.42639997601509094},{"id":"https://openalex.org/keywords/synchrotron","display_name":"Synchrotron","score":0.4135770797729492},{"id":"https://openalex.org/keywords/polymer","display_name":"Polymer","score":0.367293119430542},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3300115764141083},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.19281363487243652},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.18171116709709167},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.11752188205718994},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.10396206378936768}],"concepts":[{"id":"https://openalex.org/C131888329","wikidata":"https://www.wikidata.org/wiki/Q3027679","display_name":"Small-angle X-ray scattering","level":3,"score":0.8272418975830078},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.5757282376289368},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5197003483772278},{"id":"https://openalex.org/C168568712","wikidata":"https://www.wikidata.org/wiki/Q909999","display_name":"Radius of gyration","level":3,"score":0.5164592266082764},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.4863177239894867},{"id":"https://openalex.org/C2778297186","wikidata":"https://www.wikidata.org/wiki/Q5625393","display_name":"Gyration","level":2,"score":0.47566670179367065},{"id":"https://openalex.org/C16332341","wikidata":"https://www.wikidata.org/wiki/Q212871","display_name":"Synchrotron radiation","level":2,"score":0.44508785009384155},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4378138780593872},{"id":"https://openalex.org/C191486275","wikidata":"https://www.wikidata.org/wiki/Q210028","display_name":"Scattering","level":2,"score":0.42639997601509094},{"id":"https://openalex.org/C21368211","wikidata":"https://www.wikidata.org/wiki/Q689863","display_name":"Synchrotron","level":2,"score":0.4135770797729492},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.367293119430542},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3300115764141083},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.19281363487243652},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.18171116709709167},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11752188205718994},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.10396206378936768},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/s17061266","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s17061266","pdf_url":"https://www.mdpi.com/1424-8220/17/6/1266/pdf?version=1496401633","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:28574461","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28574461","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:oatao.univ-toulouse.fr:20376","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306401987","display_name":"Open Archive Toulouse Archive Ouverte (University of Toulouse)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I17866349","host_organization_name":"Universit\u00e9 F\u00e9d\u00e9rale de Toulouse Midi-Pyr\u00e9n\u00e9es","host_organization_lineage":["https://openalex.org/I17866349"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:HAL:hal-02134844v1","is_oa":true,"landing_page_url":"https://hal.science/hal-02134844","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, 2017, 17 (6), pp.1-12. ⟨10.3390/s17061266⟩","raw_type":"Journal articles"},{"id":"pmh:oai:europepmc.org:4343206","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5492703","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s17061266","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s17061266","pdf_url":"https://www.mdpi.com/1424-8220/17/6/1266/pdf?version=1496401633","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3050050134","display_name":null,"funder_award_id":"ANR-13-JS09-0006","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G4110391279","display_name":null,"funder_award_id":"project,","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320887","display_name":"European Synchrotron Radiation Facility","ror":"https://ror.org/02550n020"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2620974652.pdf","grobid_xml":"https://content.openalex.org/works/W2620974652.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W185745514","https://openalex.org/W598131573","https://openalex.org/W1972726303","https://openalex.org/W1972831845","https://openalex.org/W1975159161","https://openalex.org/W1994865849","https://openalex.org/W1996776705","https://openalex.org/W2001130578","https://openalex.org/W2002939536","https://openalex.org/W2009284411","https://openalex.org/W2013128723","https://openalex.org/W2014718252","https://openalex.org/W2017579460","https://openalex.org/W2020740527","https://openalex.org/W2025868537","https://openalex.org/W2027257947","https://openalex.org/W2034157543","https://openalex.org/W2037717615","https://openalex.org/W2038371089","https://openalex.org/W2042959133","https://openalex.org/W2050091361","https://openalex.org/W2053957661","https://openalex.org/W2066088601","https://openalex.org/W2067362306","https://openalex.org/W2071376671","https://openalex.org/W2072435127","https://openalex.org/W2076852946","https://openalex.org/W2091481339","https://openalex.org/W2101665118","https://openalex.org/W2116502195","https://openalex.org/W2117179092","https://openalex.org/W2124761117","https://openalex.org/W2124983865","https://openalex.org/W2126999424","https://openalex.org/W2145439094","https://openalex.org/W2151777308","https://openalex.org/W2157299819","https://openalex.org/W2162942780","https://openalex.org/W2163075507","https://openalex.org/W2169620403","https://openalex.org/W2170408275","https://openalex.org/W2192311817","https://openalex.org/W2345388039","https://openalex.org/W2475783272","https://openalex.org/W2576294924","https://openalex.org/W2594140093","https://openalex.org/W2604374969","https://openalex.org/W4301512062"],"related_works":["https://openalex.org/W2005257205","https://openalex.org/W1991418715","https://openalex.org/W2109457563","https://openalex.org/W2383509614","https://openalex.org/W2130541969","https://openalex.org/W2933383431","https://openalex.org/W1978938342","https://openalex.org/W2274081107","https://openalex.org/W3016690804","https://openalex.org/W2003693116"],"abstract_inverted_index":{"The":[0,47,166,199],"relevance":[1],"of":[2,21,29,38,63,66,79,83,152,156,163,177,181,196,218],"coupling":[3],"droplet-based":[4],"Photonic":[5],"Lab-on-a-Chip":[6],"(PhLoC)":[7],"platforms":[8,49],"and":[9,58,70,75,97,105,141,144,170,188],"Small-Angle":[10],"X-Ray":[11],"Scattering":[12],"(SAXS)":[13],"technique":[14],"is":[15,110],"here":[16],"highlighted":[17],"for":[18,149],"the":[19,27,76,107,150,184,227],"performance":[20],"high":[22],"throughput":[23],"investigations,":[24],"related":[25],"to":[26,42,56,112,128,204,223],"study":[28],"protein":[30,130,197],"macromolecular":[31],"interactions.":[32,131],"With":[33,132],"this":[34,52,133],"configuration,":[35,134],"minute":[36],"amounts":[37,65],"sample":[39,219],"are":[40,54],"required":[41],"obtain":[43],"reliable":[44],"statistical":[45],"data.":[46],"PhLoC":[48],"presented":[50],"in":[51,72,118,206,226],"work":[53],"designed":[55],"allow":[57],"control":[59,92],"an":[60,125],"effective":[61],"mixing":[62],"precise":[64],"proteins,":[67],"crystallization":[68],"reagents":[69],"buffer":[71],"nanoliter":[73],"volumes,":[74],"subsequent":[77],"generation":[78,95],"nanodroplets":[80],"by":[81],"means":[82,180],"a":[84,90,153,160,175,194,215],"two-phase":[85],"flow.":[86],"Spectrophotometric":[87],"sensing":[88],"permits":[89],"fine":[91],"on":[93,102],"droplet":[94,108,135],"frequency":[96],"stability":[98],"as":[99,101,124,174,193],"well":[100],"concentration":[103],"conditions,":[104],"finally":[106],"flow":[109],"synchronized":[111],"perform":[113],"synchrotron":[114],"radiation":[115],"SAXS":[116,182],"measurements":[117],"individual":[119],"droplets":[120],"(each":[121],"one":[122],"acting":[123],"isolated":[126],"microreactor)":[127],"probe":[129],"physic-chemical":[136],"conditions":[137,158],"can":[138],"be":[139,205],"reproducibly":[140],"finely":[142],"tuned,":[143],"monitored":[145],"without":[146],"cross-contamination,":[147],"allowing":[148],"screening":[151],"substantial":[154],"number":[155],"saturation":[157],"with":[159,209,214],"small":[161],"amount":[162],"biological":[164],"material.":[165],"setup":[167],"was":[168],"tested":[169],"validated":[171],"using":[172],"lysozyme":[173],"model":[176],"study.":[178],"By":[179],"experiments,":[183],"proteins":[185],"gyration":[186],"radius":[187],"structure":[189],"envelope":[190],"were":[191,202],"calculated":[192],"function":[195],"concentration.":[198],"obtained":[200],"values":[201],"found":[203],"good":[207],"agreement":[208],"previously":[210],"reported":[211,225],"data,":[212],"but":[213],"dramatic":[216],"reduction":[217],"volume":[220],"requirements":[221],"compared":[222],"studies":[224],"literature.":[228]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}