{"id":"https://openalex.org/W1980856039","doi":"https://doi.org/10.3390/s110606214","title":"Interfacial Chemistry and the Design of Solid-Phase Nucleic Acid Hybridization Assays Using Immobilized Quantum Dots as Donors in Fluorescence Resonance Energy Transfer","display_name":"Interfacial Chemistry and the Design of Solid-Phase Nucleic Acid Hybridization Assays Using Immobilized Quantum Dots as Donors in Fluorescence Resonance Energy Transfer","publication_year":2011,"publication_date":"2011-06-09","ids":{"openalex":"https://openalex.org/W1980856039","doi":"https://doi.org/10.3390/s110606214","mag":"1980856039","pmid":"https://pubmed.ncbi.nlm.nih.gov/22163951"},"language":"en","primary_location":{"id":"doi:10.3390/s110606214","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s110606214","pdf_url":"https://www.mdpi.com/1424-8220/11/6/6214/pdf?version=1403315327","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/11/6/6214/pdf?version=1403315327","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012704895","display_name":"W. Russ Algar","orcid":"https://orcid.org/0000-0003-3442-7072"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"W. Russ Algar","raw_affiliation_strings":["Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Rd. North, Mississauga, ON L5L 1C6, Canada"],"affiliations":[{"raw_affiliation_string":"Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Rd. North, Mississauga, ON L5L 1C6, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090709874","display_name":"Ulrich J. Krull","orcid":"https://orcid.org/0000-0001-8836-7648"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Ulrich J. Krull","raw_affiliation_strings":["Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Rd. North, Mississauga, ON L5L 1C6, Canada"],"affiliations":[{"raw_affiliation_string":"Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Rd. North, Mississauga, ON L5L 1C6, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090709874"],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2598},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2598},"fwci":2.9348,"has_fulltext":true,"cited_by_count":40,"citation_normalized_percentile":{"value":0.91302637,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"11","issue":"6","first_page":"6214","last_page":"6236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10321","display_name":"Quantum Dots Synthesis And Properties","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/f\u00f6rster-resonance-energy-transfer","display_name":"F\u00f6rster resonance energy transfer","score":0.9472472667694092},{"id":"https://openalex.org/keywords/quantum-dot","display_name":"Quantum dot","score":0.7283116579055786},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.6812572479248047},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.6475355625152588},{"id":"https://openalex.org/keywords/nucleic-acid","display_name":"Nucleic acid","score":0.5823878049850464},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.5591038465499878},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5256617665290833},{"id":"https://openalex.org/keywords/acceptor","display_name":"Acceptor","score":0.5075942277908325},{"id":"https://openalex.org/keywords/nucleic-acid-detection","display_name":"Nucleic acid detection","score":0.48351266980171204},{"id":"https://openalex.org/keywords/peptide-nucleic-acid","display_name":"Peptide nucleic acid","score":0.4636683464050293},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.2317836582660675},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.09623309969902039},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.07658147811889648}],"concepts":[{"id":"https://openalex.org/C96305047","wikidata":"https://www.wikidata.org/wiki/Q367473","display_name":"F\u00f6rster resonance energy transfer","level":3,"score":0.9472472667694092},{"id":"https://openalex.org/C124657808","wikidata":"https://www.wikidata.org/wiki/Q1133068","display_name":"Quantum dot","level":2,"score":0.7283116579055786},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.6812572479248047},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6475355625152588},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.5823878049850464},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5591038465499878},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5256617665290833},{"id":"https://openalex.org/C2779892579","wikidata":"https://www.wikidata.org/wiki/Q912138","display_name":"Acceptor","level":2,"score":0.5075942277908325},{"id":"https://openalex.org/C2910367586","wikidata":"https://www.wikidata.org/wiki/Q348667","display_name":"Nucleic acid detection","level":3,"score":0.48351266980171204},{"id":"https://openalex.org/C2777343594","wikidata":"https://www.wikidata.org/wiki/Q412152","display_name":"Peptide nucleic acid","level":3,"score":0.4636683464050293},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2317836582660675},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09623309969902039},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07658147811889648},{"id":"https://openalex.org/C26873012","wikidata":"https://www.wikidata.org/wiki/Q214781","display_name":"Condensed matter physics","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008422","descriptor_name":"Materials Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008422","descriptor_name":"Materials Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008422","descriptor_name":"Materials Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008422","descriptor_name":"Materials Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019921","descriptor_name":"Biotinylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019921","descriptor_name":"Biotinylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019921","descriptor_name":"Biotinylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019921","descriptor_name":"Biotinylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031541","descriptor_name":"Fluorescence Resonance Energy Transfer","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D031541","descriptor_name":"Fluorescence Resonance Energy Transfer","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D031541","descriptor_name":"Fluorescence Resonance Energy Transfer","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D031541","descriptor_name":"Fluorescence Resonance Energy Transfer","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.3390/s110606214","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s110606214","pdf_url":"https://www.mdpi.com/1424-8220/11/6/6214/pdf?version=1403315327","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:22163951","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22163951","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:utoronto.scholaris.ca:1807/92218","is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/92218","pdf_url":"https://utoronto.scholaris.ca/bitstreams/e0623f8c-6b9d-4ae7-a249-dfa484e6a14c/download","source":{"id":"https://openalex.org/S7407055458","display_name":"TSpace","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:6566cf72fa484bb8a5e47bec444070b9","is_oa":true,"landing_page_url":"https://doaj.org/article/6566cf72fa484bb8a5e47bec444070b9","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 11, Iss 6, Pp 6214-6236 (2011)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2240622","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3231443","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:mdpi.com:/1424-8220/11/6/6214/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/s110606214","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors; Volume 11; Issue 6; Pages: 6214-6236","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s110606214","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s110606214","pdf_url":"https://www.mdpi.com/1424-8220/11/6/6214/pdf?version=1403315327","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","score":0.8999999761581421,"display_name":"Affordable and clean energy"}],"awards":[{"id":"https://openalex.org/G2165548363","display_name":null,"funder_award_id":"Canada","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G8284766523","display_name":null,"funder_award_id":"(NSERC)","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"}],"funders":[{"id":"https://openalex.org/F4320322015","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087"},{"id":"https://openalex.org/F4320323346","display_name":"B\u1ed9 Gi\u00e1o d\u1ee5c v\u00e0 \u00d0\u00e0o t\u1ea1o","ror":"https://ror.org/00drv3378"},{"id":"https://openalex.org/F4320331574","display_name":"University of Toronto Mississauga","ror":null},{"id":"https://openalex.org/F4320333938","display_name":"Minist\u00e8re de l\u2019\u00c9ducation, Gouvernement de l\u2019Ontario","ror":null},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1980856039.pdf","grobid_xml":"https://content.openalex.org/works/W1980856039.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1966197199","https://openalex.org/W1971335428","https://openalex.org/W1973996951","https://openalex.org/W1987507852","https://openalex.org/W1990805101","https://openalex.org/W1991646828","https://openalex.org/W1991834757","https://openalex.org/W2002186962","https://openalex.org/W2008394718","https://openalex.org/W2012846906","https://openalex.org/W2015913136","https://openalex.org/W2019418566","https://openalex.org/W2022910525","https://openalex.org/W2031625978","https://openalex.org/W2032860659","https://openalex.org/W2053146969","https://openalex.org/W2053624731","https://openalex.org/W2055553636","https://openalex.org/W2062485439","https://openalex.org/W2065365980","https://openalex.org/W2073773592","https://openalex.org/W2080631899","https://openalex.org/W2086075014","https://openalex.org/W2086747651","https://openalex.org/W2087477004","https://openalex.org/W2089263424","https://openalex.org/W2094437628","https://openalex.org/W2106043217","https://openalex.org/W2138032051","https://openalex.org/W2148924929","https://openalex.org/W2151133972","https://openalex.org/W2154321074","https://openalex.org/W2321572107","https://openalex.org/W2561569335","https://openalex.org/W4252973876","https://openalex.org/W6664700881"],"related_works":["https://openalex.org/W2048074445","https://openalex.org/W2142891272","https://openalex.org/W4210581134","https://openalex.org/W1599075286","https://openalex.org/W1987066967","https://openalex.org/W4233431870","https://openalex.org/W2112976975","https://openalex.org/W2797913390","https://openalex.org/W2079357620","https://openalex.org/W2066078187"],"abstract_inverted_index":{"The":[0,98,124],"use":[1],"of":[2,20,41,55,64,73,100,114,117,126,155,178,184],"quantum":[3],"dots":[4],"(QDs)":[5],"as":[6,179,181,186,188],"donors":[7,90],"in":[8,38,95],"fluorescence":[9],"resonance":[10],"energy":[11],"transfer":[12],"(FRET)":[13],"offer":[14],"several":[15,49],"advantages":[16],"for":[17,29,58,192],"the":[18,39,53,69,92,112,122,175],"development":[19],"multiplexed":[21],"solid-phase":[22,74],"QD-FRET":[23,75],"nucleic":[24],"acid":[25],"hybridization":[26,76,85,132],"assays.":[27,77,97],"Designs":[28],"multiplexing":[30],"have":[31,144],"been":[32],"demonstrated,":[33],"but":[34],"important":[35],"challenges":[36],"remain":[37],"optimization":[40],"these":[42,96,156],"systems.":[43],"In":[44],"this":[45,165],"work,":[46],"we":[47,167],"identify":[48],"strategies":[50],"based":[51],"on":[52],"design":[54],"interfacial":[56,146,171],"chemistry":[57,172],"improving":[59,139],"sensitivity,":[60],"obtaining":[61],"lower":[62],"limits":[63],"detection":[65,177],"(LOD)":[66],"and":[67,71,110,173],"enabling":[68],"regeneration":[70],"reuse":[72],"FRET-sensitized":[78],"emission":[79],"from":[80,106],"acceptor":[81,118,128],"dyes":[82,129],"associated":[83],"with":[84,130],"events":[86],"at":[87],"immobilized":[88],"QD":[89,107],"provides":[91],"analytical":[93],"signal":[94],"minimization":[99],"active":[101],"sensing":[102],"area":[103],"reduces":[104],"background":[105],"donor":[108],"PL":[109],"allows":[111],"resolution":[113],"smaller":[115],"amounts":[116],"emission,":[119],"thus":[120],"lowering":[121],"LOD.":[123],"association":[125],"multiple":[127],"each":[131],"event":[133],"can":[134],"enhance":[135],"FRET":[136],"efficiency,":[137],"thereby":[138],"sensitivity.":[140],"Many":[141],"previous":[142],"studies":[143],"used":[145],"protein":[147],"layers":[148,157],"to":[149,160],"generate":[150],"selectivity;":[151],"however,":[152],"transient":[153],"destabilization":[154],"is":[158],"shown":[159],"prevent":[161],"efficient":[162],"regeneration.":[163,193],"To":[164],"end,":[166],"report":[168],"a":[169],"protein-free":[170],"demonstrate":[174],"specific":[176],"little":[180],"2":[182],"pmol":[183],"target,":[185],"well":[187],"an":[189],"improved":[190],"capacity":[191]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":5}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}