{"id":"https://openalex.org/W2123511930","doi":"https://doi.org/10.3390/s100100890","title":"Pterins as Sensors of Response to the Application of Fe3+-Dextran in Piglets","display_name":"Pterins as Sensors of Response to the Application of Fe3+-Dextran in Piglets","publication_year":2010,"publication_date":"2010-01-22","ids":{"openalex":"https://openalex.org/W2123511930","doi":"https://doi.org/10.3390/s100100890","mag":"2123511930","pmid":"https://pubmed.ncbi.nlm.nih.gov/22315574"},"language":"en","primary_location":{"id":"doi:10.3390/s100100890","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s100100890","pdf_url":"https://www.mdpi.com/1424-8220/10/1/890/pdf?version=1403312097","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8220/10/1/890/pdf?version=1403312097","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112157033","display_name":"Miriam Smutn\u00e1","orcid":null},"institutions":[{"id":"https://openalex.org/I113254221","display_name":"University of Veterinary Sciences Brno","ror":"https://ror.org/04rk6w354","country_code":"CZ","type":"education","lineage":["https://openalex.org/I113254221"]}],"countries":["CZ"],"is_corresponding":true,"raw_author_name":"Miriam Smutna","raw_affiliation_strings":["Department of Biochemistry, Chemistry and Biophysics, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1/3, Brno, 612 42, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Chemistry and Biophysics, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1/3, Brno, 612 42, Czech Republic","institution_ids":["https://openalex.org/I113254221"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103949025","display_name":"Martin Svoboda","orcid":null},"institutions":[{"id":"https://openalex.org/I113254221","display_name":"University of Veterinary Sciences Brno","ror":"https://ror.org/04rk6w354","country_code":"CZ","type":"education","lineage":["https://openalex.org/I113254221"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Martin Svoboda","raw_affiliation_strings":["Clinic of Pig Diseases, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1/3, Brno, 612 42, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic of Pig Diseases, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1/3, Brno, 612 42, Czech Republic","institution_ids":["https://openalex.org/I113254221"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032708633","display_name":"Kl\u00e1ra Breinekov\u00e1","orcid":null},"institutions":[{"id":"https://openalex.org/I4210146556","display_name":"Synthon (Czechia)","ror":"https://ror.org/05g777x71","country_code":"CZ","type":"company","lineage":["https://openalex.org/I4210103972","https://openalex.org/I4210146556"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Klara Breinekova","raw_affiliation_strings":["Synthon s. r. o., Brnenska 32, Blansko 678 17, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Synthon s. r. o., Brnenska 32, Blansko 678 17, Czech Republic","institution_ids":["https://openalex.org/I4210146556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112157033"],"corresponding_institution_ids":["https://openalex.org/I113254221"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2673},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2673},"fwci":0.2489,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.5688955,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"10","issue":"1","first_page":"890","last_page":"900"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9851999878883362,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9851999878883362,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13481","display_name":"Neurological diseases and metabolism","score":0.9732000231742859,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.9632999897003174,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neopterin","display_name":"Neopterin","score":0.7815462946891785},{"id":"https://openalex.org/keywords/dextran","display_name":"Dextran","score":0.7591840624809265},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.6855279207229614},{"id":"https://openalex.org/keywords/biopterin","display_name":"Biopterin","score":0.6615631580352783},{"id":"https://openalex.org/keywords/hormone","display_name":"Hormone","score":0.5841451287269592},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.46658000349998474},{"id":"https://openalex.org/keywords/animal-science","display_name":"Animal science","score":0.3839521110057831},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3689115643501282},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.3572911024093628},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.3556138277053833},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3496476709842682},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.3023737967014313},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2510935068130493}],"concepts":[{"id":"https://openalex.org/C2776603314","wikidata":"https://www.wikidata.org/wiki/Q908292","display_name":"Neopterin","level":2,"score":0.7815462946891785},{"id":"https://openalex.org/C2777339698","wikidata":"https://www.wikidata.org/wiki/Q423123","display_name":"Dextran","level":2,"score":0.7591840624809265},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6855279207229614},{"id":"https://openalex.org/C2777451243","wikidata":"https://www.wikidata.org/wiki/Q408256","display_name":"Biopterin","level":5,"score":0.6615631580352783},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5841451287269592},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46658000349998474},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.3839521110057831},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3689115643501282},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3572911024093628},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3556138277053833},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3496476709842682},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3023737967014313},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2510935068130493},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C197957613","wikidata":"https://www.wikidata.org/wiki/Q407280","display_name":"Cofactor","level":3,"score":0.0},{"id":"https://openalex.org/C2776145790","wikidata":"https://www.wikidata.org/wiki/Q419808","display_name":"Tetrahydrobiopterin","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011622","descriptor_name":"Pterins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011622","descriptor_name":"Pterins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011622","descriptor_name":"Pterins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011622","descriptor_name":"Pterins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011622","descriptor_name":"Pterins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011622","descriptor_name":"Pterins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/s100100890","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s100100890","pdf_url":"https://www.mdpi.com/1424-8220/10/1/890/pdf?version=1403312097","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},{"id":"pmid:22315574","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22315574","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:f1db3113bb9f45f7ab22fa4194de6a59","is_oa":true,"landing_page_url":"https://doaj.org/article/f1db3113bb9f45f7ab22fa4194de6a59","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sensors, Vol 10, Iss 1, Pp 890-900 (2010)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2281363","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3270875","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/s100100890","is_oa":true,"landing_page_url":"https://doi.org/10.3390/s100100890","pdf_url":"https://www.mdpi.com/1424-8220/10/1/890/pdf?version=1403312097","source":{"id":"https://openalex.org/S101949793","display_name":"Sensors","issn_l":"1424-8220","issn":["1424-8220"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2123511930.pdf","grobid_xml":"https://content.openalex.org/works/W2123511930.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W12245359","https://openalex.org/W745735898","https://openalex.org/W1498226529","https://openalex.org/W1930663416","https://openalex.org/W1956600540","https://openalex.org/W1992557216","https://openalex.org/W1994838137","https://openalex.org/W2007602535","https://openalex.org/W2011676233","https://openalex.org/W2017918524","https://openalex.org/W2026310023","https://openalex.org/W2058052923","https://openalex.org/W2064449408","https://openalex.org/W2073408716","https://openalex.org/W2077266891","https://openalex.org/W2081348073","https://openalex.org/W2090447674","https://openalex.org/W2094370941","https://openalex.org/W2107874439","https://openalex.org/W2138122208","https://openalex.org/W2141112342","https://openalex.org/W2143963254","https://openalex.org/W2330944500","https://openalex.org/W2403099824","https://openalex.org/W6600515763","https://openalex.org/W6629611660","https://openalex.org/W6640631173"],"related_works":["https://openalex.org/W1981219971","https://openalex.org/W1977408264","https://openalex.org/W2137412560","https://openalex.org/W1598461491","https://openalex.org/W2372936590","https://openalex.org/W2083357151","https://openalex.org/W1967548427","https://openalex.org/W1976992619","https://openalex.org/W2118887462","https://openalex.org/W2039925094"],"abstract_inverted_index":{"The":[0,159],"aim":[1],"of":[2,11,15,28,38,44,67,85,126,136,147,169,186,191],"the":[3,9,29,45,53,75,96,123,127,140,143,167,173,181,189],"presented":[4,161],"study":[5],"was":[6],"to":[7,35,116],"assess":[8],"effect":[10],"a":[12,40,70,163],"single":[13,65],"administration":[14],"Fe(3+)-dextran":[16,68,157],"on":[17,166,188],"immune":[18,31],"cell":[19],"counts":[20,105],"and":[21,34,50,90,103,111,142],"pterin":[22],"biomolecule":[23],"production":[24,84],"as":[25],"novel":[26],"sensors":[27],"piglets'":[30,54,76,129],"system":[32],"activation,":[33],"determine":[36],"concentrations":[37,102,121,146],"cortisol,":[39],"traditional":[41],"hormonal":[42],"biosensor":[43],"stress":[46,72,110,170],"response.":[47],"Pterins":[48],"(neopterin":[49],"biopterin)":[51],"in":[52,74,95,100,122,172,193],"blood":[55],"serum":[56,145],"were":[57,106,112,131,152],"analyzed":[58],"by":[59,81,108,133],"separation":[60],"using":[61],"reversed-phase":[62],"HPLC.":[63],"A":[64],"dose":[66],"produced":[69],"special":[71],"situation":[73],"organism":[77,175],"which":[78],"manifested":[79],"itself":[80],"an":[82,134],"increased":[83],"neopterin":[86],"(p":[87,92,149],"<":[88,93,150],"0.05)":[89],"biopterin":[91],"0.01)":[94,151],"experimental":[97,128],"piglets.":[98],"Changes":[99],"cortisol":[101],"leukocyte":[104],"influenced":[107],"handling":[109],"not":[113,177],"specifically":[114],"correlated":[115],"iron":[117,148],"dextran":[118],"application.":[119],"Iron":[120],"internal":[124],"environment":[125],"group":[130],"higher":[132],"order":[135],"magnitude":[137],"compared":[138],"with":[139],"controls,":[141],"highest":[144],"reached":[153],"24":[154],"h":[155],"following":[156],"administration.":[158],"data":[160],"offer":[162],"new":[164],"perspective":[165],"evaluation":[168],"situations":[171],"animal":[174],"and,":[176],"least":[178],"importantly,":[179],"extends":[180],"rather":[182],"modest":[183],"current":[184],"list":[185],"references":[187],"role":[190],"pterins":[192],"livestock":[194],"animals.":[195]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}