{"id":"https://openalex.org/W4409269671","doi":"https://doi.org/10.3390/info16040295","title":"A Lightweight Neural Network for Cell Segmentation Based on Attention Enhancement","display_name":"A Lightweight Neural Network for Cell Segmentation Based on Attention Enhancement","publication_year":2025,"publication_date":"2025-04-08","ids":{"openalex":"https://openalex.org/W4409269671","doi":"https://doi.org/10.3390/info16040295"},"language":"en","primary_location":{"id":"doi:10.3390/info16040295","is_oa":true,"landing_page_url":"https://doi.org/10.3390/info16040295","pdf_url":"https://www.mdpi.com/2078-2489/16/4/295/pdf?version=1744089703","source":{"id":"https://openalex.org/S4210219776","display_name":"Information","issn_l":"2078-2489","issn":["2078-2489"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Information","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2078-2489/16/4/295/pdf?version=1744089703","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101455862","display_name":"Shuang Xia","orcid":"https://orcid.org/0000-0002-5136-3704"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuang Xia","raw_affiliation_strings":["School of Information and Control Engineering, China University of Mining and Technology, Xuzhou 211116, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information and Control Engineering, China University of Mining and Technology, Xuzhou 211116, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100858018","display_name":"Qian Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210149211","display_name":"Institute of Semiconductors","ror":"https://ror.org/048dd0611","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210149211"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Sun","raw_affiliation_strings":["Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","University of Chinese Academy of Sciences, Beijing 101408, China"],"raw_orcid":"https://orcid.org/0009-0005-3128-7264","affiliations":[{"raw_affiliation_string":"Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","institution_ids":["https://openalex.org/I4210149211","https://openalex.org/I19820366"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 101408, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090589594","display_name":"Yiheng Zhou","orcid":"https://orcid.org/0000-0003-3539-3484"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210149211","display_name":"Institute of Semiconductors","ror":"https://ror.org/048dd0611","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210149211"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiheng Zhou","raw_affiliation_strings":["Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","University of Chinese Academy of Sciences, Beijing 101408, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","institution_ids":["https://openalex.org/I4210149211","https://openalex.org/I19820366"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 101408, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114143360","display_name":"Zhaoyuxuan Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210149211","display_name":"Institute of Semiconductors","ror":"https://ror.org/048dd0611","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210149211"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhaoyuxuan Wang","raw_affiliation_strings":["Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","institution_ids":["https://openalex.org/I4210149211","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chaoxing You","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210149211","display_name":"Institute of Semiconductors","ror":"https://ror.org/048dd0611","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210149211"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chaoxing You","raw_affiliation_strings":["Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","University of Chinese Academy of Sciences, Beijing 101408, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","institution_ids":["https://openalex.org/I4210149211","https://openalex.org/I19820366"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 101408, China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009817857","display_name":"Kainan Ma","orcid":"https://orcid.org/0000-0002-1379-591X"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210149211","display_name":"Institute of Semiconductors","ror":"https://ror.org/048dd0611","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210149211"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kainan Ma","raw_affiliation_strings":["Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China"],"raw_orcid":"https://orcid.org/0000-0002-1379-591X","affiliations":[{"raw_affiliation_string":"Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","institution_ids":["https://openalex.org/I4210149211","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100347816","display_name":"Ming Liu","orcid":"https://orcid.org/0000-0002-9291-8235"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210149211","display_name":"Institute of Semiconductors","ror":"https://ror.org/048dd0611","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210149211"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Liu","raw_affiliation_strings":["Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","University of Chinese Academy of Sciences, Beijing 101408, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China","institution_ids":["https://openalex.org/I4210149211","https://openalex.org/I19820366"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, Beijing 101408, China","institution_ids":["https://openalex.org/I4210165038"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5009817857"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210149211"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1515},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1515},"fwci":0.923,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.751847,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"16","issue":"4","first_page":"295","last_page":"295"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5971888303756714},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5848177671432495},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5792927742004395},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4896726906299591}],"concepts":[{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5971888303756714},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5848177671432495},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5792927742004395},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4896726906299591}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3390/info16040295","is_oa":true,"landing_page_url":"https://doi.org/10.3390/info16040295","pdf_url":"https://www.mdpi.com/2078-2489/16/4/295/pdf?version=1744089703","source":{"id":"https://openalex.org/S4210219776","display_name":"Information","issn_l":"2078-2489","issn":["2078-2489"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Information","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:9e6f422e55ab46178d919fbc7f1d2398","is_oa":true,"landing_page_url":"https://doaj.org/article/9e6f422e55ab46178d919fbc7f1d2398","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Information, Vol 16, Iss 4, p 295 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/info16040295","is_oa":true,"landing_page_url":"https://doi.org/10.3390/info16040295","pdf_url":"https://www.mdpi.com/2078-2489/16/4/295/pdf?version=1744089703","source":{"id":"https://openalex.org/S4210219776","display_name":"Information","issn_l":"2078-2489","issn":["2078-2489"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Information","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7317337458","display_name":null,"funder_award_id":"52474270","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409269671.pdf","grobid_xml":"https://content.openalex.org/works/W4409269671.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1901129140","https://openalex.org/W1903029394","https://openalex.org/W2008359794","https://openalex.org/W2032227103","https://openalex.org/W2412782625","https://openalex.org/W2533800772","https://openalex.org/W2592929672","https://openalex.org/W2731899572","https://openalex.org/W2794825826","https://openalex.org/W2884436604","https://openalex.org/W2905338897","https://openalex.org/W2947263797","https://openalex.org/W2953421783","https://openalex.org/W2955737766","https://openalex.org/W2962914239","https://openalex.org/W2963881378","https://openalex.org/W2980998394","https://openalex.org/W3093261564","https://openalex.org/W3095986980","https://openalex.org/W3096947210","https://openalex.org/W3102785203","https://openalex.org/W3123982987","https://openalex.org/W3132503749","https://openalex.org/W4206693420","https://openalex.org/W4283688005","https://openalex.org/W4285733526","https://openalex.org/W4307906997","https://openalex.org/W4312399099","https://openalex.org/W4319216049","https://openalex.org/W4323357155","https://openalex.org/W4389483415","https://openalex.org/W4392883923","https://openalex.org/W4393898938","https://openalex.org/W4401276993","https://openalex.org/W4403456736","https://openalex.org/W6925965567"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Deep":[0],"neural":[1],"networks":[2],"have":[3],"made":[4],"significant":[5,87],"strides":[6],"in":[7,89],"medical":[8,166],"image":[9,66,167],"segmentation":[10,37,116,168],"tasks,":[11],"but":[12],"their":[13,21],"large-scale":[14],"parameters":[15,95],"and":[16,57,73,96,104,122,130,148,158],"high":[17,113],"computational":[18,72],"complexity":[19],"limit":[20],"applicability":[22],"on":[23,78,139,170],"resource-constrained":[24],"edge":[25,171],"devices.":[26,172],"To":[27],"address":[28],"this":[29,31],"challenge,":[30],"paper":[32],"introduces":[33],"a":[34,112,165],"lightweight":[35,156],"nuclear":[36],"network":[38],"called":[39],"Attention-Enhanced":[40],"U-Net":[41],"(AttE-Unet)":[42],"for":[43,161],"cell":[44],"segmentation.":[45],"AttE-Unet":[46],"enhances":[47],"the":[48,59,79,92,107,119,133,154],"network\u2019s":[49],"feature":[50],"extraction":[51],"capabilities":[52],"through":[53],"an":[54,140],"attention":[55],"mechanism":[56],"combines":[58],"strengths":[60],"of":[61,94,106,115,132,146,151],"deep":[62],"learning":[63],"with":[64],"traditional":[65],"filtering":[67],"algorithms,":[68],"while":[69],"substantially":[70],"reducing":[71],"storage":[74],"demands.":[75],"Experimental":[76],"results":[77],"PanNuke":[80],"dataset":[81],"demonstrate":[82],"that":[83],"AttE-Unet,":[84],"despite":[85],"its":[86,159],"reduction":[88],"model":[90],"size\u2014with":[91],"number":[93],"floating-point":[97],"operations":[98],"per":[99],"second":[100],"reduced":[101],"to":[102],"1.57%":[103],"0.1%":[105],"original":[108,134],"model,":[109],"respectively\u2014still":[110],"maintains":[111],"level":[114],"performance.":[117],"Specifically,":[118],"F1":[120],"score":[121,127],"Intersection":[123],"over":[124],"Union":[125],"(IoU)":[126],"are":[128],"91.7%":[129],"89.3%":[131],"model\u2019s":[135,155],"scores.":[136],"Furthermore,":[137],"deployment":[138,163],"MCU":[141],"consumes":[142],"only":[143],"2.09":[144],"MB":[145,150],"Flash":[147],"1.38":[149],"RAM,":[152],"highlighting":[153],"nature":[157],"potential":[160],"practical":[162],"as":[164],"solution":[169]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}