{"id":"https://openalex.org/W4384666819","doi":"https://doi.org/10.3390/e25071074","title":"Temporospatial Nestedness in Consciousness: An Updated Perspective on the Temporospatial Theory of Consciousness","display_name":"Temporospatial Nestedness in Consciousness: An Updated Perspective on the Temporospatial Theory of Consciousness","publication_year":2023,"publication_date":"2023-07-17","ids":{"openalex":"https://openalex.org/W4384666819","doi":"https://doi.org/10.3390/e25071074","pmid":"https://pubmed.ncbi.nlm.nih.gov/37510023"},"language":"en","primary_location":{"id":"doi:10.3390/e25071074","is_oa":true,"landing_page_url":"https://doi.org/10.3390/e25071074","pdf_url":"https://www.mdpi.com/1099-4300/25/7/1074/pdf?version=1689591049","source":{"id":"https://openalex.org/S195231649","display_name":"Entropy","issn_l":"1099-4300","issn":["1099-4300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1099-4300/25/7/1074/pdf?version=1689591049","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001464571","display_name":"Zirui Huang","orcid":"https://orcid.org/0000-0002-5949-0206"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Zirui Huang","raw_affiliation_strings":["Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109, USA","Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA"],"raw_orcid":"https://orcid.org/0000-0002-5949-0206","affiliations":[{"raw_affiliation_string":"Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5001464571"],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2165},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2165},"fwci":0.5111,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.62891177,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"25","issue":"7","first_page":"1074","last_page":"1074"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nestedness","display_name":"Nestedness","score":0.8268914222717285},{"id":"https://openalex.org/keywords/consciousness","display_name":"Consciousness","score":0.8103596568107605},{"id":"https://openalex.org/keywords/relation","display_name":"Relation (database)","score":0.5054931640625},{"id":"https://openalex.org/keywords/cognitive-science","display_name":"Cognitive science","score":0.5029682517051697},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3582267761230469},{"id":"https://openalex.org/keywords/epistemology","display_name":"Epistemology","score":0.3563276529312134},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.33252012729644775},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1918909251689911},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.1581183671951294},{"id":"https://openalex.org/keywords/philosophy","display_name":"Philosophy","score":0.13845938444137573},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09982296824455261},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.08331069350242615}],"concepts":[{"id":"https://openalex.org/C2780267512","wikidata":"https://www.wikidata.org/wiki/Q6997828","display_name":"Nestedness","level":3,"score":0.8268914222717285},{"id":"https://openalex.org/C186720457","wikidata":"https://www.wikidata.org/wiki/Q7087","display_name":"Consciousness","level":2,"score":0.8103596568107605},{"id":"https://openalex.org/C25343380","wikidata":"https://www.wikidata.org/wiki/Q277521","display_name":"Relation (database)","level":2,"score":0.5054931640625},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.5029682517051697},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3582267761230469},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.3563276529312134},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.33252012729644775},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1918909251689911},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.1581183671951294},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.13845938444137573},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09982296824455261},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.08331069350242615},{"id":"https://openalex.org/C185933670","wikidata":"https://www.wikidata.org/wiki/Q52105","display_name":"Habitat","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/e25071074","is_oa":true,"landing_page_url":"https://doi.org/10.3390/e25071074","pdf_url":"https://www.mdpi.com/1099-4300/25/7/1074/pdf?version=1689591049","source":{"id":"https://openalex.org/S195231649","display_name":"Entropy","issn_l":"1099-4300","issn":["1099-4300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy","raw_type":"journal-article"},{"id":"pmid:37510023","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37510023","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10378228","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10378228","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10378228/pdf/entropy-25-01074.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Entropy (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:9af03600f0434af1ab8599e6f8741650","is_oa":true,"landing_page_url":"https://doaj.org/article/9af03600f0434af1ab8599e6f8741650","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Entropy, Vol 25, Iss 7, p 1074 (2023)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1099-4300/25/7/1074/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/e25071074","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Entropy; Volume 25; Issue 7; Pages: 1074","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/e25071074","is_oa":true,"landing_page_url":"https://doi.org/10.3390/e25071074","pdf_url":"https://www.mdpi.com/1099-4300/25/7/1074/pdf?version=1689591049","source":{"id":"https://openalex.org/S195231649","display_name":"Entropy","issn_l":"1099-4300","issn":["1099-4300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G138111407","display_name":null,"funder_award_id":"R01-GM103894","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2973284583","display_name":null,"funder_award_id":"R01-GM103894","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3860426689","display_name":null,"funder_award_id":"T32-GM103730","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3983614178","display_name":null,"funder_award_id":"GM103894","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4384666819.pdf"},"referenced_works_count":140,"referenced_works":["https://openalex.org/W1495993332","https://openalex.org/W1507893557","https://openalex.org/W1559787775","https://openalex.org/W1603307924","https://openalex.org/W1829346027","https://openalex.org/W1929542974","https://openalex.org/W1964308889","https://openalex.org/W1967064349","https://openalex.org/W1969374641","https://openalex.org/W1991825895","https://openalex.org/W1994341528","https://openalex.org/W1996032190","https://openalex.org/W2000930046","https://openalex.org/W2005933475","https://openalex.org/W2007997142","https://openalex.org/W2015303758","https://openalex.org/W2016702702","https://openalex.org/W2019370496","https://openalex.org/W2027238322","https://openalex.org/W2030737932","https://openalex.org/W2031012527","https://openalex.org/W2033236989","https://openalex.org/W2034532999","https://openalex.org/W2045823870","https://openalex.org/W2049208961","https://openalex.org/W2058807673","https://openalex.org/W2059512699","https://openalex.org/W2065561795","https://openalex.org/W2066488827","https://openalex.org/W2066835186","https://openalex.org/W2072799373","https://openalex.org/W2087302183","https://openalex.org/W2088992072","https://openalex.org/W2097780816","https://openalex.org/W2097954642","https://openalex.org/W2100831964","https://openalex.org/W2102204212","https://openalex.org/W2105558714","https://openalex.org/W2108604460","https://openalex.org/W2114359844","https://openalex.org/W2116360511","https://openalex.org/W2116533103","https://openalex.org/W2122263166","https://openalex.org/W2122799871","https://openalex.org/W2122872927","https://openalex.org/W2123170884","https://openalex.org/W2125115665","https://openalex.org/W2125136217","https://openalex.org/W2127501699","https://openalex.org/W2129317350","https://openalex.org/W2133299302","https://openalex.org/W2135390742","https://openalex.org/W2135840784","https://openalex.org/W2140531572","https://openalex.org/W2147401077","https://openalex.org/W2147546041","https://openalex.org/W2148791497","https://openalex.org/W2152009360","https://openalex.org/W2154348072","https://openalex.org/W2155959642","https://openalex.org/W2157105539","https://openalex.org/W2162010696","https://openalex.org/W2171783484","https://openalex.org/W2177128208","https://openalex.org/W2218504993","https://openalex.org/W2336630210","https://openalex.org/W2339840868","https://openalex.org/W2394834952","https://openalex.org/W2536956629","https://openalex.org/W2546767664","https://openalex.org/W2567675234","https://openalex.org/W2607177050","https://openalex.org/W2737989178","https://openalex.org/W2741986628","https://openalex.org/W2747342147","https://openalex.org/W2765507708","https://openalex.org/W2773293192","https://openalex.org/W2773503363","https://openalex.org/W2783076752","https://openalex.org/W2786504149","https://openalex.org/W2786964764","https://openalex.org/W2789389748","https://openalex.org/W2886680918","https://openalex.org/W2889959197","https://openalex.org/W2909745138","https://openalex.org/W2945067895","https://openalex.org/W2950254084","https://openalex.org/W2964595868","https://openalex.org/W2970958859","https://openalex.org/W2983229964","https://openalex.org/W3004874674","https://openalex.org/W3009555114","https://openalex.org/W3012472614","https://openalex.org/W3016741470","https://openalex.org/W3018854448","https://openalex.org/W3023421984","https://openalex.org/W3035420228","https://openalex.org/W3039330297","https://openalex.org/W3048423161","https://openalex.org/W3081424244","https://openalex.org/W3081489731","https://openalex.org/W3093856228","https://openalex.org/W3099900825","https://openalex.org/W3105313416","https://openalex.org/W3107189325","https://openalex.org/W3110881055","https://openalex.org/W3112207296","https://openalex.org/W3118861474","https://openalex.org/W3127231159","https://openalex.org/W3128927736","https://openalex.org/W3149159936","https://openalex.org/W3155706952","https://openalex.org/W3159510851","https://openalex.org/W3176528706","https://openalex.org/W3179426622","https://openalex.org/W3185598997","https://openalex.org/W3193752863","https://openalex.org/W4200077041","https://openalex.org/W4206411254","https://openalex.org/W4206996248","https://openalex.org/W4210887302","https://openalex.org/W4211239355","https://openalex.org/W4213260613","https://openalex.org/W4220749750","https://openalex.org/W4220874291","https://openalex.org/W4221117400","https://openalex.org/W4225414052","https://openalex.org/W4226218677","https://openalex.org/W4288447410","https://openalex.org/W4309714543","https://openalex.org/W4309922072","https://openalex.org/W4309930795","https://openalex.org/W4312140284","https://openalex.org/W4313281277","https://openalex.org/W4313571673","https://openalex.org/W4360823161","https://openalex.org/W4365515021","https://openalex.org/W4376114573","https://openalex.org/W6675234877","https://openalex.org/W6679898406"],"related_works":["https://openalex.org/W2186035063","https://openalex.org/W1503217837","https://openalex.org/W1989997625","https://openalex.org/W21463351","https://openalex.org/W2113773025","https://openalex.org/W2107224662","https://openalex.org/W2526467952","https://openalex.org/W2245467156","https://openalex.org/W2142680372","https://openalex.org/W4200556610"],"abstract_inverted_index":{"Time":[0],"and":[1,12,20,45,64,97,121,128,147,170],"space":[2],"are":[3],"fundamental":[4,62],"elements":[5],"that":[6,39],"permeate":[7],"the":[8,50,61,68,75,90,94,101,106,116,122,132,158,165,175],"fabric":[9],"of":[10,28,33,78,85,100,108,118,143,168,174],"nature,":[11],"their":[13],"significance":[14],"in":[15],"relation":[16],"to":[17,151,160],"neural":[18,43,166],"activity":[19],"consciousness":[21,169],"remains":[22],"a":[23,37,71,139],"compelling":[24],"yet":[25],"unexplored":[26],"area":[27],"research.":[29],"The":[30],"Temporospatial":[31],"Theory":[32],"Consciousness":[34],"(TTC)":[35],"provides":[36],"framework":[38],"links":[40,133],"time,":[41],"space,":[42],"activity,":[44],"consciousness,":[46],"shedding":[47],"light":[48],"on":[49,74],"intricate":[51],"relationships":[52],"among":[53],"these":[54,135],"dimensions.":[55],"In":[56],"this":[57],"review,":[58],"I":[59,81],"revisit":[60],"concepts":[63],"mechanisms":[65],"proposed":[66],"by":[67,88],"TTC,":[69],"with":[70],"particular":[72],"focus":[73],"central":[76],"concept":[77],"temporospatial":[79,86,109],"nestedness.":[80],"propose":[82],"an":[83],"extension":[84],"nestedness":[87],"incorporating":[89],"nested":[91],"relationship":[92],"between":[93,134],"temporal":[95,123,129,148],"circuit":[96,124],"functional":[98,119],"geometry":[99,120],"brain.":[102],"To":[103],"further":[104],"unravel":[105],"complexities":[107],"nestedness,":[110],"future":[111],"research":[112],"directions":[113],"should":[114],"emphasize":[115],"characterization":[117],"across":[125],"multiple":[126],"spatial":[127,145],"scales.":[130],"Investigating":[131],"scales":[136],"will":[137],"yield":[138],"more":[140],"comprehensive":[141],"understanding":[142,173],"how":[144],"organization":[146],"dynamics":[149],"contribute":[150],"conscious":[152],"states.":[153],"This":[154],"integrative":[155],"approach":[156],"holds":[157],"potential":[159],"uncover":[161],"novel":[162],"insights":[163],"into":[164],"basis":[167],"reshape":[171],"our":[172],"world-brain":[176],"dynamic.":[177]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}
