{"id":"https://openalex.org/W3045621499","doi":"https://doi.org/10.3390/e22080826","title":"Alteration of the Intra- and Inter-Lobe Connectivity of the Brain Structural Network in Normal Aging","display_name":"Alteration of the Intra- and Inter-Lobe Connectivity of the Brain Structural Network in Normal Aging","publication_year":2020,"publication_date":"2020-07-28","ids":{"openalex":"https://openalex.org/W3045621499","doi":"https://doi.org/10.3390/e22080826","mag":"3045621499","pmid":"https://pubmed.ncbi.nlm.nih.gov/33286597"},"language":"en","primary_location":{"id":"doi:10.3390/e22080826","is_oa":true,"landing_page_url":"https://doi.org/10.3390/e22080826","pdf_url":"https://www.mdpi.com/1099-4300/22/8/826/pdf?version=1596184586","source":{"id":"https://openalex.org/S195231649","display_name":"Entropy","issn_l":"1099-4300","issn":["1099-4300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1099-4300/22/8/826/pdf?version=1596184586","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089341288","display_name":"Chi\u2010Wen Jao","orcid":"https://orcid.org/0000-0002-5138-0715"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I96323854","display_name":"National Yang Ming Chiao Tung University","ror":null,"country_code":"TW","type":null,"lineage":["https://openalex.org/I96323854"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Wen Jao","raw_affiliation_strings":["Department of Research, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan","Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan","institution_ids":[]},{"raw_affiliation_string":"Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I96323854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113912244","display_name":"Jiann-Horng Yeh","orcid":null},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jiann-Horng Yeh","raw_affiliation_strings":["Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan","School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan","institution_ids":[]},{"raw_affiliation_string":"School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242, Taiwan","institution_ids":["https://openalex.org/I114150738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080942813","display_name":"Yu\u2010Te Wu","orcid":"https://orcid.org/0000-0002-6942-0340"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I96323854","display_name":"National Yang Ming Chiao Tung University","ror":null,"country_code":"TW","type":null,"lineage":["https://openalex.org/I96323854"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yu-Te Wu","raw_affiliation_strings":["Brain Research Center, National Yang-Ming University, Taipei 112, Taiwan","Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brain Research Center, National Yang-Ming University, Taipei 112, Taiwan","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I96323854"]},{"raw_affiliation_string":"Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I96323854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110153600","display_name":"Li-Ming Lien","orcid":null},"institutions":[{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Li-Ming Lien","raw_affiliation_strings":["Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan","Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan","institution_ids":["https://openalex.org/I47519274"]},{"raw_affiliation_string":"Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111866252","display_name":"Yuh-Feng Tsai","orcid":null},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yuh-Feng Tsai","raw_affiliation_strings":["Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 112, Taiwan","School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 112, Taiwan","institution_ids":[]},{"raw_affiliation_string":"School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242, Taiwan","institution_ids":["https://openalex.org/I114150738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076880501","display_name":"Kuang-En Chu","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kuang-En Chu","raw_affiliation_strings":["Department of Gastroenterology, Shin Kong Wo Ho-Su Memorial Hospital, Taipei 112, Taiwan","Health Management Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Shin Kong Wo Ho-Su Memorial Hospital, Taipei 112, Taiwan","institution_ids":[]},{"raw_affiliation_string":"Health Management Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067859772","display_name":"Chen\u2010Yu Hsiao","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chen-Yu Hsiao","raw_affiliation_strings":["Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 112, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 112, Taiwan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113912245","display_name":"Po-Shan Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I3020248675","display_name":"Taipei Municipal YangMing Hospital","ror":"https://ror.org/047n4ns40","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I3020248675"]},{"id":"https://openalex.org/I96323854","display_name":"National Yang Ming Chiao Tung University","ror":null,"country_code":"TW","type":null,"lineage":["https://openalex.org/I96323854"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Po-Shan Wang","raw_affiliation_strings":["Department of Neurology, Taipei Municipal Gan-Dau Hospital, Taipei 112, Taiwan","Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Taipei Municipal Gan-Dau Hospital, Taipei 112, Taiwan","institution_ids":["https://openalex.org/I3020248675"]},{"raw_affiliation_string":"Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I96323854"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012943327","display_name":"Chi Ieong Lau","orcid":"https://orcid.org/0000-0003-0699-2234"},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]},{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I96323854","display_name":"National Yang Ming Chiao Tung University","ror":null,"country_code":"TW","type":null,"lineage":["https://openalex.org/I96323854"]}],"countries":["GB","MO","TW"],"is_corresponding":true,"raw_author_name":"Chi Ieong Lau","raw_affiliation_strings":["Applied Cognitive Neuroscience Group, Institute of Cognitive Neuroscience, University College London, London 01322, UK","Dementia Center, Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 112, Taiwan","Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan","School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242, Taiwan","University Hospital, Taipa 112, Macau"],"raw_orcid":"https://orcid.org/0000-0003-0699-2234","affiliations":[{"raw_affiliation_string":"Applied Cognitive Neuroscience Group, Institute of Cognitive Neuroscience, University College London, London 01322, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Dementia Center, Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 112, Taiwan","institution_ids":[]},{"raw_affiliation_string":"Institute of Biophotonics, National Yang-Ming University, Taipei 112, Taiwan","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I96323854"]},{"raw_affiliation_string":"School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242, Taiwan","institution_ids":["https://openalex.org/I114150738"]},{"raw_affiliation_string":"University Hospital, Taipa 112, Macau","institution_ids":["https://openalex.org/I204512498"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5012943327"],"corresponding_institution_ids":["https://openalex.org/I114150738","https://openalex.org/I148366613","https://openalex.org/I204512498","https://openalex.org/I45129253","https://openalex.org/I96323854"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2165},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2165},"fwci":0.6851,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.67338804,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"22","issue":"8","first_page":"826","last_page":"826"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lobe","display_name":"Lobe","score":0.6759849786758423},{"id":"https://openalex.org/keywords/temporal-lobe","display_name":"Temporal lobe","score":0.6394511461257935},{"id":"https://openalex.org/keywords/atrophy","display_name":"Atrophy","score":0.6093822717666626},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5898515582084656},{"id":"https://openalex.org/keywords/occipital-lobe","display_name":"Occipital lobe","score":0.520363986492157},{"id":"https://openalex.org/keywords/frontal-lobe","display_name":"Frontal lobe","score":0.5156713724136353},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.5114137530326843},{"id":"https://openalex.org/keywords/commissure","display_name":"Commissure","score":0.5081801414489746},{"id":"https://openalex.org/keywords/lateralization-of-brain-function","display_name":"Lateralization of brain function","score":0.4438436031341553},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.306223064661026},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2965157628059387},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.26080185174942017},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.13192015886306763},{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.07525312900543213}],"concepts":[{"id":"https://openalex.org/C2777876421","wikidata":"https://www.wikidata.org/wiki/Q1637174","display_name":"Lobe","level":2,"score":0.6759849786758423},{"id":"https://openalex.org/C2781099131","wikidata":"https://www.wikidata.org/wiki/Q744385","display_name":"Temporal lobe","level":3,"score":0.6394511461257935},{"id":"https://openalex.org/C2781172350","wikidata":"https://www.wikidata.org/wiki/Q194520","display_name":"Atrophy","level":2,"score":0.6093822717666626},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5898515582084656},{"id":"https://openalex.org/C2778046553","wikidata":"https://www.wikidata.org/wiki/Q848340","display_name":"Occipital lobe","level":2,"score":0.520363986492157},{"id":"https://openalex.org/C2777127467","wikidata":"https://www.wikidata.org/wiki/Q749520","display_name":"Frontal lobe","level":2,"score":0.5156713724136353},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5114137530326843},{"id":"https://openalex.org/C100207259","wikidata":"https://www.wikidata.org/wiki/Q489628","display_name":"Commissure","level":2,"score":0.5081801414489746},{"id":"https://openalex.org/C79840881","wikidata":"https://www.wikidata.org/wiki/Q1080497","display_name":"Lateralization of brain function","level":2,"score":0.4438436031341553},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.306223064661026},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2965157628059387},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26080185174942017},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13192015886306763},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.07525312900543213}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/e22080826","is_oa":true,"landing_page_url":"https://doi.org/10.3390/e22080826","pdf_url":"https://www.mdpi.com/1099-4300/22/8/826/pdf?version=1596184586","source":{"id":"https://openalex.org/S195231649","display_name":"Entropy","issn_l":"1099-4300","issn":["1099-4300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy","raw_type":"journal-article"},{"id":"pmid:33286597","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33286597","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy (Basel, Switzerland)","raw_type":null},{"id":"pmh:oai:doaj.org/article:f5e733f6838548f8b20582d072150c41","is_oa":true,"landing_page_url":"https://doaj.org/article/f5e733f6838548f8b20582d072150c41","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Entropy, Vol 22, Iss 8, p 826 (2020)","raw_type":"article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10197615","is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10197615/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"   Entropy , 22  (8)    , Article 826. (2020)      ","raw_type":"Article"},{"id":"pmh:oai:mdpi.com:/1099-4300/22/8/826/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/e22080826","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Entropy; Volume 22; Issue 8; Pages: 826","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7517412","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7517412","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Entropy (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/e22080826","is_oa":true,"landing_page_url":"https://doi.org/10.3390/e22080826","pdf_url":"https://www.mdpi.com/1099-4300/22/8/826/pdf?version=1596184586","source":{"id":"https://openalex.org/S195231649","display_name":"Entropy","issn_l":"1099-4300","issn":["1099-4300"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Entropy","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8250570581","display_name":null,"funder_award_id":"109GB006-3","funder_id":"https://openalex.org/F4320322544","funder_display_name":"Shin Kong Wu Ho-Su Memorial Hospital"}],"funders":[{"id":"https://openalex.org/F4320322544","display_name":"Shin Kong Wu Ho-Su Memorial Hospital","ror":"https://ror.org/04x744g62"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3045621499.pdf","grobid_xml":"https://content.openalex.org/works/W3045621499.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1734366871","https://openalex.org/W1901020111","https://openalex.org/W1929876078","https://openalex.org/W1963552978","https://openalex.org/W1969324628","https://openalex.org/W1977131470","https://openalex.org/W1977845408","https://openalex.org/W2005821483","https://openalex.org/W2007538972","https://openalex.org/W2013848365","https://openalex.org/W2013930506","https://openalex.org/W2017987256","https://openalex.org/W2023831571","https://openalex.org/W2032426886","https://openalex.org/W2046820344","https://openalex.org/W2050852481","https://openalex.org/W2052590556","https://openalex.org/W2070791497","https://openalex.org/W2070797880","https://openalex.org/W2086887105","https://openalex.org/W2090813996","https://openalex.org/W2091465235","https://openalex.org/W2094426896","https://openalex.org/W2094788831","https://openalex.org/W2101135654","https://openalex.org/W2103069600","https://openalex.org/W2106990053","https://openalex.org/W2107337180","https://openalex.org/W2114549884","https://openalex.org/W2123687120","https://openalex.org/W2128314959","https://openalex.org/W2128366083","https://openalex.org/W2138991775","https://openalex.org/W2143742215","https://openalex.org/W2145417436","https://openalex.org/W2151936673","https://openalex.org/W2153367517","https://openalex.org/W2157296433","https://openalex.org/W2162039581","https://openalex.org/W2165020693","https://openalex.org/W2165687585","https://openalex.org/W2171652727","https://openalex.org/W2221197707","https://openalex.org/W2336479189","https://openalex.org/W2338124004","https://openalex.org/W2341654072","https://openalex.org/W2561810854","https://openalex.org/W2750561105","https://openalex.org/W2896245451","https://openalex.org/W2922862637","https://openalex.org/W2952299562","https://openalex.org/W2952574438","https://openalex.org/W3011200488","https://openalex.org/W3011378388","https://openalex.org/W3027474636","https://openalex.org/W6637666633","https://openalex.org/W6639765830","https://openalex.org/W6755384234","https://openalex.org/W6775227274"],"related_works":["https://openalex.org/W3007949265","https://openalex.org/W1981494703","https://openalex.org/W1501093796","https://openalex.org/W4235682551","https://openalex.org/W2037004283","https://openalex.org/W4240544025","https://openalex.org/W1964320420","https://openalex.org/W2421551680","https://openalex.org/W4282590064","https://openalex.org/W4205412776"],"abstract_inverted_index":{"The":[0,75,149],"morphological":[1],"changes":[2],"in":[3,61,82,96,126,136,167,193],"cortical":[4,47],"parcellated":[5,46],"regions":[6,93,98],"during":[7],"aging":[8],"and":[9,19,56,68,86,116,129,139,160,173,189,196],"whether":[10],"these":[11,89],"atrophies":[12],"may":[13,176],"cause":[14],"brain":[15,181],"structural":[16,37,51,182],"network":[17,38,52,183],"intra-":[18,55,195],"inter-lobe":[20,57,146,162,197],"connectivity":[21,125,135,163],"alterations":[22],"are":[23],"subjects":[24],"that":[25],"have":[26,177],"been":[27],"minimally":[28],"explored.":[29],"In":[30],"this":[31],"study,":[32],"a":[33,62],"novel":[34],"fractal":[35,90],"dimension-based":[36],"was":[39],"proposed":[40],"to":[41,184],"measure":[42],"atrophy":[43,81],"of":[44,50,88,99],"68":[45],"regions.":[48],"Alterations":[49],"parameters,":[53],"including":[54],"connectivity,":[58,187],"were":[59,94],"detected":[60],"middle-aged":[63],"group":[64,71,77,107,151],"(30-45":[65],"years":[66,73],"old)":[67],"an":[69],"elderly":[70,76,106,150],"(50-65":[72],"old).":[74],"exhibited":[78,144],"significant":[79],"lateralized":[80],"the":[83,97,100,105,127,137,168,180],"left":[84],"hemisphere,":[85],"most":[87],"dimension":[91],"atrophied":[92],"included":[95],"\"last-in,":[101],"first-out\"":[102],"model.":[103],"Globally,":[104],"had":[108,122],"lower":[109,123],"modularity":[110],"values,":[111],"smaller":[112],"component":[113],"size":[114],"modules,":[115],"fewer":[117],"bilateral":[118],"association":[119,156],"fibers.":[120],"They":[121],"intra-lobe":[124,134],"frontal":[128],"parietal":[130],"lobes,":[131],"but":[132],"higher":[133],"temporal":[138],"occipital":[140],"lobes.":[141],"Both":[142],"groups":[143],"similar":[145],"connecting":[147],"pattern.":[148],"revealed":[152],"separations,":[153],"sparser":[154],"long":[155],"fibers,":[157,159],"commissural":[158],"lateral":[161],"lost":[164],"effect,":[165],"mainly":[166],"right":[169],"hemisphere.":[170],"New":[171],"wiring":[172],"reconfiguring":[174],"modules":[175],"occurred":[178],"within":[179],"compensate":[185],"for":[186],"decreasing":[188],"preventing":[190],"functional":[191],"loss":[192],"cerebral":[194],"connectivity.":[198]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}