{"id":"https://openalex.org/W4307437010","doi":"https://doi.org/10.3390/data7110145","title":"In Vitro Major Arterial Cardiovascular Simulator to Generate Benchmark Data Sets for In Silico Model Validation","display_name":"In Vitro Major Arterial Cardiovascular Simulator to Generate Benchmark Data Sets for In Silico Model Validation","publication_year":2022,"publication_date":"2022-10-27","ids":{"openalex":"https://openalex.org/W4307437010","doi":"https://doi.org/10.3390/data7110145"},"language":"en","primary_location":{"id":"doi:10.3390/data7110145","is_oa":true,"landing_page_url":"https://doi.org/10.3390/data7110145","pdf_url":"https://www.mdpi.com/2306-5729/7/11/145/pdf?version=1667296942","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2306-5729/7/11/145/pdf?version=1667296942","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053630404","display_name":"Michelle Wisotzki","orcid":null},"institutions":[{"id":"https://openalex.org/I45155027","display_name":"Technische Hochschule Mittelhessen","ror":"https://ror.org/02qdc9985","country_code":"DE","type":"education","lineage":["https://openalex.org/I45155027"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michelle Wisotzki","raw_affiliation_strings":["Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany"],"affiliations":[{"raw_affiliation_string":"Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany","institution_ids":["https://openalex.org/I45155027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048714906","display_name":"Alexander Mair","orcid":null},"institutions":[{"id":"https://openalex.org/I45155027","display_name":"Technische Hochschule Mittelhessen","ror":"https://ror.org/02qdc9985","country_code":"DE","type":"education","lineage":["https://openalex.org/I45155027"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexander Mair","raw_affiliation_strings":["Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany"],"affiliations":[{"raw_affiliation_string":"Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany","institution_ids":["https://openalex.org/I45155027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082404231","display_name":"Paul Schlett","orcid":null},"institutions":[{"id":"https://openalex.org/I45155027","display_name":"Technische Hochschule Mittelhessen","ror":"https://ror.org/02qdc9985","country_code":"DE","type":"education","lineage":["https://openalex.org/I45155027"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Paul Schlett","raw_affiliation_strings":["Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany"],"affiliations":[{"raw_affiliation_string":"Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany","institution_ids":["https://openalex.org/I45155027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027467296","display_name":"Bernhard Lindner","orcid":null},"institutions":[{"id":"https://openalex.org/I45155027","display_name":"Technische Hochschule Mittelhessen","ror":"https://ror.org/02qdc9985","country_code":"DE","type":"education","lineage":["https://openalex.org/I45155027"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bernhard Lindner","raw_affiliation_strings":["Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany"],"affiliations":[{"raw_affiliation_string":"Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany","institution_ids":["https://openalex.org/I45155027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003624588","display_name":"Max Oberhardt","orcid":null},"institutions":[{"id":"https://openalex.org/I45155027","display_name":"Technische Hochschule Mittelhessen","ror":"https://ror.org/02qdc9985","country_code":"DE","type":"education","lineage":["https://openalex.org/I45155027"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Max Oberhardt","raw_affiliation_strings":["Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany"],"affiliations":[{"raw_affiliation_string":"Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany","institution_ids":["https://openalex.org/I45155027"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055401511","display_name":"Stefan Bernhard","orcid":"https://orcid.org/0000-0002-4920-523X"},"institutions":[{"id":"https://openalex.org/I45155027","display_name":"Technische Hochschule Mittelhessen","ror":"https://ror.org/02qdc9985","country_code":"DE","type":"education","lineage":["https://openalex.org/I45155027"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Stefan Bernhard","raw_affiliation_strings":["Department of Mathematics and Computer Science, Freie Universit\u00e4t Berlin, Arnimallee 6, 14195 Berlin, Germany","Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Mathematics and Computer Science, Freie Universit\u00e4t Berlin, Arnimallee 6, 14195 Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]},{"raw_affiliation_string":"Technische Hochschule Mittelhessen, Faculty of Life Science Engineering, Institute of Biomedical Engineering (IBMT), Wiesenstrasse 14, 35390 Giessen, Germany","institution_ids":["https://openalex.org/I45155027"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5055401511"],"corresponding_institution_ids":["https://openalex.org/I45155027","https://openalex.org/I75951250"],"apc_list":{"value":1600,"currency":"CHF","value_usd":1732},"apc_paid":{"value":1600,"currency":"CHF","value_usd":1732},"fwci":1.3131,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.81950913,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"7","issue":"11","first_page":"145","last_page":"145"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.695561408996582},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5401045680046082},{"id":"https://openalex.org/keywords/simulation","display_name":"Simulation","score":0.48421192169189453},{"id":"https://openalex.org/keywords/flow","display_name":"Flow (mathematics)","score":0.4683021306991577},{"id":"https://openalex.org/keywords/blood-flow","display_name":"Blood flow","score":0.4463561475276947},{"id":"https://openalex.org/keywords/computational-model","display_name":"Computational model","score":0.4326707720756531},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3846466541290283},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.2861121892929077},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.24262651801109314},{"id":"https://openalex.org/keywords/mechanics","display_name":"Mechanics","score":0.10541379451751709},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09281203150749207},{"id":"https://openalex.org/keywords/geology","display_name":"Geology","score":0.08285188674926758}],"concepts":[{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.695561408996582},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5401045680046082},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.48421192169189453},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.4683021306991577},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.4463561475276947},{"id":"https://openalex.org/C66024118","wikidata":"https://www.wikidata.org/wiki/Q1122506","display_name":"Computational model","level":2,"score":0.4326707720756531},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3846466541290283},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.2861121892929077},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24262651801109314},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.10541379451751709},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09281203150749207},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.08285188674926758},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/data7110145","is_oa":true,"landing_page_url":"https://doi.org/10.3390/data7110145","pdf_url":"https://www.mdpi.com/2306-5729/7/11/145/pdf?version=1667296942","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:0506344777b94e32b1daa17b6003f921","is_oa":true,"landing_page_url":"https://doaj.org/article/0506344777b94e32b1daa17b6003f921","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Data, Vol 7, Iss 11, p 145 (2022)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/2306-5729/7/11/145/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/data7110145","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Data; Volume 7; Issue 11; Pages: 145","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/data7110145","is_oa":true,"landing_page_url":"https://doi.org/10.3390/data7110145","pdf_url":"https://www.mdpi.com/2306-5729/7/11/145/pdf?version=1667296942","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.46000000834465027,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4307437010.pdf","grobid_xml":"https://content.openalex.org/works/W4307437010.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1657184954","https://openalex.org/W1753773873","https://openalex.org/W1982009363","https://openalex.org/W1985023991","https://openalex.org/W2054569850","https://openalex.org/W2059871513","https://openalex.org/W2092543371","https://openalex.org/W2099098561","https://openalex.org/W2110101054","https://openalex.org/W2110222353","https://openalex.org/W2168308757","https://openalex.org/W2176976203","https://openalex.org/W2283958186","https://openalex.org/W2315164877","https://openalex.org/W2530017167","https://openalex.org/W2743890791","https://openalex.org/W2753579923","https://openalex.org/W2766586661","https://openalex.org/W2895298710","https://openalex.org/W2958136400","https://openalex.org/W3132554660","https://openalex.org/W3154719090","https://openalex.org/W3162012457","https://openalex.org/W3217267591","https://openalex.org/W4220930114","https://openalex.org/W4236801843","https://openalex.org/W4253797853","https://openalex.org/W4307437010"],"related_works":["https://openalex.org/W2378211422","https://openalex.org/W2745001401","https://openalex.org/W4321353415","https://openalex.org/W2130974462","https://openalex.org/W972276598","https://openalex.org/W4246352526","https://openalex.org/W2028665553","https://openalex.org/W4230315250","https://openalex.org/W1968770722","https://openalex.org/W2541045029"],"abstract_inverted_index":{"Cardiovascular":[0],"diseases":[1],"are":[2,45,75,164,180,211],"commonly":[3],"caused":[4],"by":[5,115,138,182],"atherosclerosis,":[6],"stenosis":[7],"and":[8,37,81,95,107,122,135,162,172,187,208,217,226,234,245,268,281],"aneurysms.":[9],"Understanding":[10],"the":[11,18,53,131,149,197,224,229,263,279],"influence":[12,222],"of":[13,40,55,70,89,105,196,223,228,251,272,283],"these":[14],"pathological":[15,38,108],"conditions":[16,39],"on":[17,48,231],"circulatory":[19],"mechanism":[20],"is":[21,92,136,259,276],"required":[22],"to":[23,34,77,93,100,119,213,262],"establish":[24],"methods":[25],"for":[26,59,84,201,266],"early":[27],"diagnosis.":[28],"Different":[29],"tools":[30],"have":[31],"been":[32],"developed":[33],"simulate":[35],"healthy":[36,106],"blood":[41,232],"flow.":[42],"These":[43],"simulations":[44],"often":[46,66],"based":[47],"computational":[49,64,273,284],"models":[50,65,286],"that":[51,278],"allow":[52,120],"generation":[54],"large":[56],"data":[57,83,103,199,257],"sets":[58,104],"further":[60],"investigation.":[61],"However,":[62],"because":[63],"lack":[67],"some":[68],"aspects":[69],"real-world":[71],"data,":[72],"hardware":[73,98,128],"simulators":[74],"used":[76],"close":[78],"this":[79,90],"gap":[80],"generate":[82,101],"model":[85],"validation.":[86],"The":[87,110,125,170,206,221,239,255],"aim":[88],"study":[91],"develop":[94],"validate":[96],"a":[97,139,144,167,193],"simulator":[99,129],"benchmark":[102,256],"conditions.":[109,220],"development":[111],"process":[112],"was":[113,236],"led":[114],"specific":[116],"design":[117],"criteria":[118],"flexible":[121],"physiological":[123,219],"simulations.":[124],"in":[126,202,214],"vitro":[127],"includes":[130],"major":[132],"33":[133],"arteries":[134],"driven":[137],"ventricular":[140],"assist":[141],"device":[142],"generating":[143],"parametrised":[145],"in-flow":[146],"condition":[147],"at":[148,175],"heart":[150,156],"node.":[151],"Physiologic":[152],"flow":[153,173,190,209,235,246],"conditions,":[154],"including":[155],"rate,":[157],"systolic/diastolic":[158],"pressure,":[159],"peripheral":[160],"resistance":[161],"compliance,":[163],"adjustable":[165],"across":[166],"wide":[168],"range.":[169],"pressure":[171,185,207,233,244],"waves":[174,210],"17":[176],"+":[177],"1":[178],"locations":[179],"measured":[181],"inverted":[183],"fluid-resistant":[184],"transducers":[186],"one":[188],"ultrasound":[189],"transducer,":[191],"supporting":[192],"detailed":[194],"analysis":[195],"measurement":[198],"even":[200],"silico":[203],"modelling":[204],"applications.":[205],"compared":[212],"vivo":[215],"measurements":[216],"show":[218],"degree":[225,250],"location":[227],"stenoses":[230],"also":[237],"investigated.":[238],"results":[240],"indicate":[241],"decreasing":[242],"translesional":[243],"with":[247],"an":[248],"increasing":[249],"stenosis,":[252],"as":[253],"expected.":[254],"set":[258],"made":[260],"available":[261],"research":[264],"community":[265],"validating":[267],"comparing":[269],"different":[270],"types":[271],"models.":[274],"It":[275],"hoped":[277],"validation":[280],"improvement":[282],"simulation":[285],"will":[287],"provide":[288],"better":[289],"clinical":[290],"predictions.":[291]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2022-11-01T00:00:00"}
