{"id":"https://openalex.org/W2783781492","doi":"https://doi.org/10.3390/data3010004","title":"CoeViz: A Web-Based Integrative Platform for Interactive Visualization of Large Similarity and Distance Matrices","display_name":"CoeViz: A Web-Based Integrative Platform for Interactive Visualization of Large Similarity and Distance Matrices","publication_year":2018,"publication_date":"2018-01-13","ids":{"openalex":"https://openalex.org/W2783781492","doi":"https://doi.org/10.3390/data3010004","mag":"2783781492","pmid":"https://pubmed.ncbi.nlm.nih.gov/29423399"},"language":"en","primary_location":{"id":"doi:10.3390/data3010004","is_oa":true,"landing_page_url":"https://doi.org/10.3390/data3010004","pdf_url":"https://www.mdpi.com/2306-5729/3/1/4/pdf?version=1515829647","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2306-5729/3/1/4/pdf?version=1515829647","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000935700","display_name":"Frazier N. Baker","orcid":"https://orcid.org/0000-0001-5972-1409"},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frazier Baker","raw_affiliation_strings":["Center for Autoimmune Genomics and Etiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA","Department of Electrical Engineering and Computing Systems, University of Cincinnati, Cincinnati, OH 45221, USA","Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Autoimmune Genomics and Etiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Department of Electrical Engineering and Computing Systems, University of Cincinnati, Cincinnati, OH 45221, USA","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090468327","display_name":"Aleksey Porollo","orcid":"https://orcid.org/0000-0002-3202-5099"},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I92156820","display_name":"University of Cincinnati Medical Center","ror":"https://ror.org/02p72h367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I92156820"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Aleksey Porollo","raw_affiliation_strings":["Center for Autoimmune Genomics and Etiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA","Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA","Division of Biomedical Informatics, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA","Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA","Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA"],"raw_orcid":"https://orcid.org/0000-0002-3202-5099","affiliations":[{"raw_affiliation_string":"Center for Autoimmune Genomics and Etiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA","institution_ids":["https://openalex.org/I92156820"]},{"raw_affiliation_string":"Division of Biomedical Informatics, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH 45229, USA","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA","institution_ids":["https://openalex.org/I1285204247"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090468327"],"corresponding_institution_ids":["https://openalex.org/I1285204247","https://openalex.org/I92156820"],"apc_list":{"value":1600,"currency":"CHF","value_usd":1732},"apc_paid":{"value":1600,"currency":"CHF","value_usd":1732},"fwci":0.8378,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.71665843,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"3","issue":"1","first_page":"4","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9876999855041504,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multidimensional-scaling","display_name":"Multidimensional scaling","score":0.7280687689781189},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7229104042053223},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.6723325252532959},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.6625696420669556},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5557352304458618},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.5488041043281555},{"id":"https://openalex.org/keywords/distance-matrices-in-phylogeny","display_name":"Distance matrices in phylogeny","score":0.5340952277183533},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.48364531993865967},{"id":"https://openalex.org/keywords/dimensionality-reduction","display_name":"Dimensionality reduction","score":0.46559393405914307},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.4256570041179657},{"id":"https://openalex.org/keywords/data-visualization","display_name":"Data visualization","score":0.41924503445625305},{"id":"https://openalex.org/keywords/reciprocal","display_name":"Reciprocal","score":0.41075190901756287},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.38811084628105164},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.27802225947380066},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.22851794958114624},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.1420990526676178},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.11332428455352783},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.10048052668571472}],"concepts":[{"id":"https://openalex.org/C91682802","wikidata":"https://www.wikidata.org/wiki/Q620538","display_name":"Multidimensional scaling","level":2,"score":0.7280687689781189},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7229104042053223},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.6723325252532959},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.6625696420669556},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5557352304458618},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.5488041043281555},{"id":"https://openalex.org/C5349765","wikidata":"https://www.wikidata.org/wiki/Q5282866","display_name":"Distance matrices in phylogeny","level":2,"score":0.5340952277183533},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.48364531993865967},{"id":"https://openalex.org/C70518039","wikidata":"https://www.wikidata.org/wiki/Q16000077","display_name":"Dimensionality reduction","level":2,"score":0.46559393405914307},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.4256570041179657},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.41924503445625305},{"id":"https://openalex.org/C2777742833","wikidata":"https://www.wikidata.org/wiki/Q1964083","display_name":"Reciprocal","level":2,"score":0.41075190901756287},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.38811084628105164},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.27802225947380066},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.22851794958114624},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1420990526676178},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.11332428455352783},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.10048052668571472},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/data3010004","is_oa":true,"landing_page_url":"https://doi.org/10.3390/data3010004","pdf_url":"https://www.mdpi.com/2306-5729/3/1/4/pdf?version=1515829647","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},{"id":"pmid:29423399","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29423399","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":null},{"id":"pmh:oai:RePEc:gam:jdataj:v:3:y:2018:i:1:p:4-:d:126783","is_oa":false,"landing_page_url":"https://www.mdpi.com/2306-5729/3/1/4/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:7ef82f73cf4b461289b4713dbc1fc3b6","is_oa":true,"landing_page_url":"https://doaj.org/article/7ef82f73cf4b461289b4713dbc1fc3b6","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Data, Vol 3, Iss 1, p 4 (2018)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/2306-5729/3/1/4/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/data3010004","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Data; Volume 3; Issue 1; Pages: 4","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5798608","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5798608","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Data (Basel)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/data3010004","is_oa":true,"landing_page_url":"https://doi.org/10.3390/data3010004","pdf_url":"https://www.mdpi.com/2306-5729/3/1/4/pdf?version=1515829647","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1643264655","display_name":null,"funder_award_id":"8UL1TR000077","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G6126732080","display_name":null,"funder_award_id":"8UL1TR000077","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2783781492.pdf","grobid_xml":"https://content.openalex.org/works/W2783781492.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1982583124","https://openalex.org/W2107867854","https://openalex.org/W2107956427","https://openalex.org/W2130479394","https://openalex.org/W2135415614","https://openalex.org/W2137184377","https://openalex.org/W2141627824","https://openalex.org/W2147085530","https://openalex.org/W2301217054","https://openalex.org/W2560695073"],"related_works":["https://openalex.org/W2769164545","https://openalex.org/W2345947583","https://openalex.org/W2963259149","https://openalex.org/W4205700962","https://openalex.org/W4206437220","https://openalex.org/W102821606","https://openalex.org/W2964133779","https://openalex.org/W4238212629","https://openalex.org/W157479946","https://openalex.org/W2106297084"],"abstract_inverted_index":{"Similarity":[0],"and":[1,33,63,103,116,151,161],"distance":[2],"matrices":[3,26,75],"are":[4],"general":[5],"data":[6,61,136],"structures":[7],"that":[8,56],"describe":[9],"reciprocal":[10],"relationships":[11],"between":[12],"the":[13,44,49,90,124,127,130],"objects":[14],"within":[15],"a":[16,40,86,106],"given":[17],"dataset.":[18],"Commonly":[19],"used":[20],"methods":[21],"for":[22,43,59,73,89,129],"representation":[23],"of":[24,36,46,51,93,99,126,132,141,154],"these":[25],"include":[27],"heatmaps,":[28],"hierarchical":[29,110],"trees,":[30],"dimensionality":[31],"reduction,":[32],"various":[34],"types":[35],"networks.":[37],"However,":[38],"despite":[39],"well-developed":[41],"foundation":[42],"visualization":[45],"such":[47,157],"representations,":[48],"challenge":[50],"creating":[52],"an":[53],"interactive":[54,91,109],"view":[55],"would":[57],"allow":[58],"quick":[60,150],"navigation":[62],"interpretation":[64],"remains":[65],"largely":[66],"unaddressed.":[67],"This":[68],"problem":[69],"becomes":[70],"especially":[71],"evident":[72],"large":[74,94],"with":[76],"hundreds":[77],"or":[78],"thousands":[79],"objects.":[80],"In":[81],"this":[82],"work,":[83],"we":[84],"present":[85],"web-based":[87],"platform":[88,128],"analysis":[92,131,153],"(dis-)similarity":[95],"matrices.":[96],"It":[97],"consists":[98],"four":[100],"major":[101],"interconnected":[102],"synchronized":[104],"components:":[105],"zoomable":[107],"heatmap,":[108],"tree,":[111],"scalable":[112],"circular":[113],"relationship":[114],"diagram,":[115],"3D":[117],"multi-dimensional":[118],"scaling":[119],"(MDS)":[120],"scatterplot.":[121],"We":[122],"demonstrate":[123],"use":[125],"amino":[133],"acid":[134],"covariance":[135],"in":[137],"proteins":[138],"as":[139,158],"part":[140],"our":[142],"previously":[143],"developed":[144],"CoeViz":[145],"tool.":[146],"The":[147],"web-platform":[148],"enables":[149],"focused":[152],"protein":[155],"features,":[156],"structural":[159],"domains":[160],"functional":[162],"sites.":[163]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}