{"id":"https://openalex.org/W4200579534","doi":"https://doi.org/10.3390/computation9120146","title":"The Reasonable Effectiveness of Randomness in Scalable and Integrative Gene Regulatory Network Inference and Beyond","display_name":"The Reasonable Effectiveness of Randomness in Scalable and Integrative Gene Regulatory Network Inference and Beyond","publication_year":2021,"publication_date":"2021-12-20","ids":{"openalex":"https://openalex.org/W4200579534","doi":"https://doi.org/10.3390/computation9120146"},"language":"en","primary_location":{"id":"doi:10.3390/computation9120146","is_oa":true,"landing_page_url":"https://doi.org/10.3390/computation9120146","pdf_url":"https://www.mdpi.com/2079-3197/9/12/146/pdf?version=1640074015","source":{"id":"https://openalex.org/S2738402919","display_name":"Computation","issn_l":"2079-3197","issn":["2079-3197"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-3197/9/12/146/pdf?version=1640074015","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020606529","display_name":"Michael Banf","orcid":"https://orcid.org/0000-0002-4312-6004"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Michael Banf","raw_affiliation_strings":["EducatedGuess.ai, 57290 Neunkirchen, Germany"],"raw_orcid":"https://orcid.org/0000-0002-4312-6004","affiliations":[{"raw_affiliation_string":"EducatedGuess.ai, 57290 Neunkirchen, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054100778","display_name":"Thomas Hartwig","orcid":"https://orcid.org/0000-0002-2707-2771"},"institutions":[{"id":"https://openalex.org/I4210141639","display_name":"Max Planck Institute for Plant Breeding Research","ror":"https://ror.org/044g3zk14","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210141639"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Thomas Hartwig","raw_affiliation_strings":["Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany"],"raw_orcid":"https://orcid.org/0000-0002-2707-2771","affiliations":[{"raw_affiliation_string":"Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany","institution_ids":["https://openalex.org/I4210141639"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020606529","https://openalex.org/A5054100778"],"corresponding_institution_ids":["https://openalex.org/I4210141639"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1515},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1515},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13165072,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"12","first_page":"146","last_page":"146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.7196391820907593},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.7089109420776367},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.6095588803291321},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5803160667419434},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.5178639888763428},{"id":"https://openalex.org/keywords/randomness","display_name":"Randomness","score":0.5177154541015625},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5081841945648193},{"id":"https://openalex.org/keywords/biological-data","display_name":"Biological data","score":0.4502222239971161},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.43522557616233826},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4115697145462036},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3833416700363159},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3496062755584717},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2991761863231659},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2720319628715515},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.26836711168289185},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1842467486858368},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.09877419471740723},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08916303515434265}],"concepts":[{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.7196391820907593},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.7089109420776367},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.6095588803291321},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5803160667419434},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.5178639888763428},{"id":"https://openalex.org/C125112378","wikidata":"https://www.wikidata.org/wiki/Q176640","display_name":"Randomness","level":2,"score":0.5177154541015625},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5081841945648193},{"id":"https://openalex.org/C201797286","wikidata":"https://www.wikidata.org/wiki/Q4914986","display_name":"Biological data","level":2,"score":0.4502222239971161},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.43522557616233826},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4115697145462036},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3833416700363159},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3496062755584717},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2991761863231659},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2720319628715515},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.26836711168289185},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1842467486858368},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.09877419471740723},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08916303515434265},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/computation9120146","is_oa":true,"landing_page_url":"https://doi.org/10.3390/computation9120146","pdf_url":"https://www.mdpi.com/2079-3197/9/12/146/pdf?version=1640074015","source":{"id":"https://openalex.org/S2738402919","display_name":"Computation","issn_l":"2079-3197","issn":["2079-3197"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computation","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:6593ea0f9f37429888b3a2ce253cec55","is_oa":true,"landing_page_url":"https://doaj.org/article/6593ea0f9f37429888b3a2ce253cec55","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computation, Vol 9, Iss 12, p 146 (2021)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/2079-3197/9/12/146/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/computation9120146","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computation; Volume 9; Issue 12; Pages: 146","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/computation9120146","is_oa":true,"landing_page_url":"https://doi.org/10.3390/computation9120146","pdf_url":"https://www.mdpi.com/2079-3197/9/12/146/pdf?version=1640074015","source":{"id":"https://openalex.org/S2738402919","display_name":"Computation","issn_l":"2079-3197","issn":["2079-3197"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computation","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3856896707","display_name":null,"funder_award_id":"DFG HA 9073","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200579534.pdf"},"referenced_works_count":203,"referenced_works":["https://openalex.org/W29579115","https://openalex.org/W92469554","https://openalex.org/W621546036","https://openalex.org/W1019830208","https://openalex.org/W1560821253","https://openalex.org/W1573849430","https://openalex.org/W1638203394","https://openalex.org/W1794986754","https://openalex.org/W1829361182","https://openalex.org/W1907700015","https://openalex.org/W1937291806","https://openalex.org/W1966744507","https://openalex.org/W1968691112","https://openalex.org/W1970576574","https://openalex.org/W1971106435","https://openalex.org/W1974254202","https://openalex.org/W1975726561","https://openalex.org/W1982168843","https://openalex.org/W1987523347","https://openalex.org/W1989440127","https://openalex.org/W1995875735","https://openalex.org/W2002586473","https://openalex.org/W2002709996","https://openalex.org/W2004026774","https://openalex.org/W2005330159","https://openalex.org/W2015148262","https://openalex.org/W2022731279","https://openalex.org/W2025987231","https://openalex.org/W2028904582","https://openalex.org/W2032619610","https://openalex.org/W2032627084","https://openalex.org/W2035023834","https://openalex.org/W2036108598","https://openalex.org/W2037219647","https://openalex.org/W2037541952","https://openalex.org/W2038622868","https://openalex.org/W2051445099","https://openalex.org/W2054044693","https://openalex.org/W2055397908","https://openalex.org/W2059357290","https://openalex.org/W2063978378","https://openalex.org/W2065734030","https://openalex.org/W2067580807","https://openalex.org/W2067666373","https://openalex.org/W2069645361","https://openalex.org/W2070757897","https://openalex.org/W2076513103","https://openalex.org/W2078644058","https://openalex.org/W2089497633","https://openalex.org/W2090037139","https://openalex.org/W2091273510","https://openalex.org/W2092988184","https://openalex.org/W2093830031","https://openalex.org/W2104042033","https://openalex.org/W2104618447","https://openalex.org/W2106142493","https://openalex.org/W2108207895","https://openalex.org/W2108393596","https://openalex.org/W2108786888","https://openalex.org/W2109384743","https://openalex.org/W2109715726","https://openalex.org/W2111872968","https://openalex.org/W2112616044","https://openalex.org/W2114804254","https://openalex.org/W2115664087","https://openalex.org/W2116194650","https://openalex.org/W2117314216","https://openalex.org/W2117527407","https://openalex.org/W2117756735","https://openalex.org/W2117757143","https://openalex.org/W2118723994","https://openalex.org/W2119387367","https://openalex.org/W2122640316","https://openalex.org/W2124166542","https://openalex.org/W2126345910","https://openalex.org/W2129016996","https://openalex.org/W2132692097","https://openalex.org/W2133240688","https://openalex.org/W2135046866","https://openalex.org/W2136787567","https://openalex.org/W2137465688","https://openalex.org/W2138309709","https://openalex.org/W2142826916","https://openalex.org/W2145073242","https://openalex.org/W2145631015","https://openalex.org/W2145976686","https://openalex.org/W2147292097","https://openalex.org/W2147440110","https://openalex.org/W2147524392","https://openalex.org/W2149118429","https://openalex.org/W2156508863","https://openalex.org/W2160365721","https://openalex.org/W2164998314","https://openalex.org/W2165786088","https://openalex.org/W2167189305","https://openalex.org/W2167433878","https://openalex.org/W2168919539","https://openalex.org/W2169053773","https://openalex.org/W2171111703","https://openalex.org/W2177265991","https://openalex.org/W2178844003","https://openalex.org/W2205907925","https://openalex.org/W2225156818","https://openalex.org/W2263825730","https://openalex.org/W2284253967","https://openalex.org/W2307267906","https://openalex.org/W2315452447","https://openalex.org/W2344526199","https://openalex.org/W2394933259","https://openalex.org/W2433743436","https://openalex.org/W2461460074","https://openalex.org/W2465336312","https://openalex.org/W2474886434","https://openalex.org/W2480854438","https://openalex.org/W2488424576","https://openalex.org/W2501518520","https://openalex.org/W2502949459","https://openalex.org/W2504378310","https://openalex.org/W2508944576","https://openalex.org/W2512392141","https://openalex.org/W2518319998","https://openalex.org/W2520902279","https://openalex.org/W2523285811","https://openalex.org/W2552604774","https://openalex.org/W2579624238","https://openalex.org/W2582038667","https://openalex.org/W2583780192","https://openalex.org/W2589838901","https://openalex.org/W2594105393","https://openalex.org/W2611138580","https://openalex.org/W2621113402","https://openalex.org/W2781869913","https://openalex.org/W2790385355","https://openalex.org/W2791183315","https://openalex.org/W2797372563","https://openalex.org/W2803928488","https://openalex.org/W2805950880","https://openalex.org/W2885564894","https://openalex.org/W2892055372","https://openalex.org/W2892313722","https://openalex.org/W2899545492","https://openalex.org/W2904970666","https://openalex.org/W2911964244","https://openalex.org/W2912029926","https://openalex.org/W2914183398","https://openalex.org/W2922701384","https://openalex.org/W2940589961","https://openalex.org/W2950245999","https://openalex.org/W2951446896","https://openalex.org/W2951531839","https://openalex.org/W2952382191","https://openalex.org/W2954663106","https://openalex.org/W2958555575","https://openalex.org/W2962703949","https://openalex.org/W2963450965","https://openalex.org/W2966153276","https://openalex.org/W2969742128","https://openalex.org/W2970771711","https://openalex.org/W2979473749","https://openalex.org/W2989061519","https://openalex.org/W2989747508","https://openalex.org/W2990735891","https://openalex.org/W2990975805","https://openalex.org/W2996227376","https://openalex.org/W2997831639","https://openalex.org/W2999009832","https://openalex.org/W2999484921","https://openalex.org/W3003444384","https://openalex.org/W3003471562","https://openalex.org/W3004700632","https://openalex.org/W3012280517","https://openalex.org/W3032683009","https://openalex.org/W3036780692","https://openalex.org/W3083805655","https://openalex.org/W3088462269","https://openalex.org/W3094050552","https://openalex.org/W3100379134","https://openalex.org/W3100510456","https://openalex.org/W3104164593","https://openalex.org/W3113349968","https://openalex.org/W3116663947","https://openalex.org/W3124443216","https://openalex.org/W3128303471","https://openalex.org/W3149361930","https://openalex.org/W3152443338","https://openalex.org/W3152493721","https://openalex.org/W3164212224","https://openalex.org/W3173875945","https://openalex.org/W3177403885","https://openalex.org/W3189015187","https://openalex.org/W3191661929","https://openalex.org/W4231916799","https://openalex.org/W4234698323","https://openalex.org/W4255299645","https://openalex.org/W4286824699","https://openalex.org/W4292023222","https://openalex.org/W4394669802","https://openalex.org/W6666708836","https://openalex.org/W6681651645","https://openalex.org/W6685040470","https://openalex.org/W6751893364","https://openalex.org/W6765380767","https://openalex.org/W6792673697"],"related_works":["https://openalex.org/W2155492529","https://openalex.org/W4252504573","https://openalex.org/W2158714033","https://openalex.org/W4385510321","https://openalex.org/W15348386","https://openalex.org/W2949927938","https://openalex.org/W2314128295","https://openalex.org/W3213185671","https://openalex.org/W78967844","https://openalex.org/W2131550814"],"abstract_inverted_index":{"Gene":[0],"regulation":[1],"is":[2,37,187,252],"orchestrated":[3],"by":[4,32],"a":[5,40,51,157,176,190,209,257,261],"vast":[6],"number":[7,95],"of":[8,42,56,63,77,96,109,119,137,170,218,232,269,272,280,294],"molecules,":[9],"including":[10,44],"transcription":[11],"factors":[12],"and":[13,22,112,116,222,229,248,267,296,303],"co-factors,":[14],"chromatin":[15],"regulators,":[16],"as":[17,19,208],"well":[18],"epigenetic":[20],"mechanisms,":[21],"it":[23],"has":[24,60],"been":[25],"shown":[26],"that":[27,89],"transcriptional":[28,83],"misregulation,":[29],"e.g.,":[30],"caused":[31],"mutations":[33],"in":[34,68,81,122,134,163,175,213,290],"regulatory":[35,58,131,181,235,283],"sequences,":[36],"responsible":[38],"for":[39,142,260],"plethora":[41],"diseases,":[43],"cancer,":[45],"developmental":[46],"or":[47,145],"neurological":[48],"disorders.":[49],"As":[50,166],"consequence,":[52],"decoding":[53],"the":[54,64,78,82,93,114,127,135,171,227,233,264,270,277,292],"architecture":[55],"gene":[57,180,234],"networks":[59],"become":[61],"one":[62,169,287],"most":[65],"important":[66],"tasks":[67],"modern":[69],"(computational)":[70],"biology.":[71,165],"However,":[72],"to":[73,106,124,149,155,160,201,245,255,301],"advance":[74],"our":[75,241,253],"understanding":[76,291],"mechanisms":[79,293],"involved":[80],"apparatus,":[84],"we":[85,199,239],"need":[86,105],"scalable":[87],"approaches":[88,104,152],"can":[90],"deal":[91],"with":[92,215],"increasing":[94,216],"large-scale,":[97,219],"high-resolution,":[98],"biological":[99,115,220,249],"datasets.":[100],"In":[101,195],"particular,":[102,214],"such":[103,120],"be":[107,156,286],"capable":[108],"efficiently":[110],"integrating":[111],"exploiting":[113],"technological":[117],"heterogeneity":[118],"datasets":[121,223],"order":[123],"best":[125],"infer":[126],"underlying,":[128],"highly":[129,210,281],"dynamic":[130],"networks,":[132],"often":[133],"absence":[136],"sufficient":[138],"ground":[139],"truth":[140],"data":[141,186],"model":[143],"training":[144],"testing.":[146],"With":[147],"respect":[148],"scalability,":[150],"randomized":[151,204,273],"have":[153],"proven":[154],"promising":[158],"alternative":[159],"deterministic":[161],"methods":[162,205],"computational":[164,247],"an":[167],"example,":[168],"top":[172],"performing":[173],"algorithms":[174],"community":[177],"challenge":[178],"on":[179,189],"network":[182,236],"inference":[183,237],"from":[184],"transcriptomic":[185],"based":[188],"random":[191],"forest":[192],"regression":[193],"model.":[194],"this":[196],"concise":[197],"survey,":[198],"aim":[200,254],"highlight":[202],"how":[203],"may":[206],"serve":[207],"valuable":[211],"tool,":[212],"amounts":[217],"experiments":[221],"being":[224],"collected.":[225],"Given":[226],"complexity":[228],"interdisciplinary":[230],"nature":[231],"problem,":[238],"hope":[240],"survey":[242],"maybe":[243],"helpful":[244],"both":[246],"scientists.":[250],"It":[251],"provide":[256],"starting":[258],"point":[259],"dialogue":[262],"about":[263],"concepts,":[265],"benefits,":[266],"caveats":[268],"toolbox":[271],"methods,":[274],"since":[275],"unravelling":[276],"intricate":[278],"web":[279],"dynamic,":[282],"events":[284],"will":[285],"fundamental":[288],"step":[289],"life":[295],"eventually":[297],"developing":[298],"efficient":[299],"therapies":[300],"treat":[302],"cure":[304],"diseases.":[305]},"counts_by_year":[],"updated_date":"2026-05-22T06:13:13.366637","created_date":"2025-10-10T00:00:00"}