{"id":"https://openalex.org/W3003757127","doi":"https://doi.org/10.3390/computation8010010","title":"Targeted Drug Delivery of Magnetic Nano-Particle in the Specific Lung Region","display_name":"Targeted Drug Delivery of Magnetic Nano-Particle in the Specific Lung Region","publication_year":2020,"publication_date":"2020-02-04","ids":{"openalex":"https://openalex.org/W3003757127","doi":"https://doi.org/10.3390/computation8010010","mag":"3003757127"},"language":"en","primary_location":{"id":"doi:10.3390/computation8010010","is_oa":true,"landing_page_url":"https://doi.org/10.3390/computation8010010","pdf_url":"https://www.mdpi.com/2079-3197/8/1/10/pdf?version=1580796067","source":{"id":"https://openalex.org/S2738402919","display_name":"Computation","issn_l":"2079-3197","issn":["2079-3197"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-3197/8/1/10/pdf?version=1580796067","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091637398","display_name":"Anusmriti Ghosh","orcid":"https://orcid.org/0000-0003-1456-5304"},"institutions":[{"id":"https://openalex.org/I160993911","display_name":"Queensland University of Technology","ror":"https://ror.org/03pnv4752","country_code":"AU","type":"education","lineage":["https://openalex.org/I160993911"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Anusmriti Ghosh","raw_affiliation_strings":["School of Chemistry, Physics & Mechanical Engineering, Queensland University of Technology (QUT), 2 George Street, GPO Box 2434, Brisbane, QLD 4001, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Physics & Mechanical Engineering, Queensland University of Technology (QUT), 2 George Street, GPO Box 2434, Brisbane, QLD 4001, Australia","institution_ids":["https://openalex.org/I160993911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083747975","display_name":"Mohammad S. Islam","orcid":"https://orcid.org/0000-0001-6264-3886"},"institutions":[{"id":"https://openalex.org/I114017466","display_name":"University of Technology Sydney","ror":"https://ror.org/03f0f6041","country_code":"AU","type":"education","lineage":["https://openalex.org/I114017466"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Mohammad S. Islam","raw_affiliation_strings":["School of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, New South Wales 2007, Australia"],"raw_orcid":"https://orcid.org/0000-0001-6264-3886","affiliations":[{"raw_affiliation_string":"School of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, New South Wales 2007, Australia","institution_ids":["https://openalex.org/I114017466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046488213","display_name":"Suvash C. Saha","orcid":"https://orcid.org/0000-0002-9962-8919"},"institutions":[{"id":"https://openalex.org/I114017466","display_name":"University of Technology Sydney","ror":"https://ror.org/03f0f6041","country_code":"AU","type":"education","lineage":["https://openalex.org/I114017466"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Suvash C. Saha","raw_affiliation_strings":["School of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, New South Wales 2007, Australia"],"raw_orcid":"https://orcid.org/0000-0002-9962-8919","affiliations":[{"raw_affiliation_string":"School of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, New South Wales 2007, Australia","institution_ids":["https://openalex.org/I114017466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5046488213"],"corresponding_institution_ids":["https://openalex.org/I114017466"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1515},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1515},"fwci":3.0378,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.93260745,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"10","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12163","display_name":"Aerosol Filtration and Electrostatic Precipitation","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12350","display_name":"Particle Dynamics in Fluid Flows","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2212","display_name":"Ocean Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-delivery","display_name":"Drug delivery","score":0.5624750256538391},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"Targeted drug delivery","score":0.5331522822380066},{"id":"https://openalex.org/keywords/lung","display_name":"Lung","score":0.43241047859191895},{"id":"https://openalex.org/keywords/magnetic-nanoparticles","display_name":"Magnetic nanoparticles","score":0.4194633364677429},{"id":"https://openalex.org/keywords/mechanics","display_name":"Mechanics","score":0.4087328016757965},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3928494453430176},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.38359305262565613},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.33507925271987915},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28819650411605835},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.168441504240036},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.09558439254760742}],"concepts":[{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.5624750256538391},{"id":"https://openalex.org/C126511603","wikidata":"https://www.wikidata.org/wiki/Q1261145","display_name":"Targeted drug delivery","level":3,"score":0.5331522822380066},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.43241047859191895},{"id":"https://openalex.org/C87023908","wikidata":"https://www.wikidata.org/wiki/Q3870166","display_name":"Magnetic nanoparticles","level":3,"score":0.4194633364677429},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.4087328016757965},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3928494453430176},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.38359305262565613},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.33507925271987915},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28819650411605835},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.168441504240036},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09558439254760742}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/computation8010010","is_oa":true,"landing_page_url":"https://doi.org/10.3390/computation8010010","pdf_url":"https://www.mdpi.com/2079-3197/8/1/10/pdf?version=1580796067","source":{"id":"https://openalex.org/S2738402919","display_name":"Computation","issn_l":"2079-3197","issn":["2079-3197"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computation","raw_type":"journal-article"},{"id":"pmh:oai:eprints.qut.edu.au:137170","is_oa":true,"landing_page_url":null,"pdf_url":"https://eprints.qut.edu.au/137170/1/computation_08_00010_1_.pdf","source":{"id":"https://openalex.org/S4306402607","display_name":"QUT ePrints (Queensland University of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I160993911","host_organization_name":"Queensland University of Technology","host_organization_lineage":["https://openalex.org/I160993911"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computation","raw_type":"Contribution to Journal"},{"id":"pmh:oai:doaj.org/article:142b761f976c4d8e81955fe8c8f2464f","is_oa":true,"landing_page_url":"https://doaj.org/article/142b761f976c4d8e81955fe8c8f2464f","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computation, Vol 8, Iss 1, p 10 (2020)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/2079-3197/8/1/10/","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/computation8010010","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computation","raw_type":"Text"},{"id":"pmh:oai:opus.lib.uts.edu.au:10453/138373","is_oa":true,"landing_page_url":"http://hdl.handle.net/10453/138373","pdf_url":null,"source":{"id":"https://openalex.org/S4306401357","display_name":"UTS ePRESS (University of Technology Sydney)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I114017466","host_organization_name":"University of Technology Sydney","host_organization_lineage":["https://openalex.org/I114017466"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/computation8010010","is_oa":true,"landing_page_url":"https://doi.org/10.3390/computation8010010","pdf_url":"https://www.mdpi.com/2079-3197/8/1/10/pdf?version=1580796067","source":{"id":"https://openalex.org/S2738402919","display_name":"Computation","issn_l":"2079-3197","issn":["2079-3197"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computation","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7900000214576721,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3003757127.pdf","grobid_xml":"https://content.openalex.org/works/W3003757127.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W764982041","https://openalex.org/W1107959744","https://openalex.org/W1135720400","https://openalex.org/W1972063621","https://openalex.org/W1993706573","https://openalex.org/W1994245699","https://openalex.org/W2025471734","https://openalex.org/W2028281612","https://openalex.org/W2033468145","https://openalex.org/W2039181066","https://openalex.org/W2046794774","https://openalex.org/W2052831705","https://openalex.org/W2072836030","https://openalex.org/W2080689908","https://openalex.org/W2082349971","https://openalex.org/W2088603650","https://openalex.org/W2110305797","https://openalex.org/W2137640349","https://openalex.org/W2137890360","https://openalex.org/W2274110787","https://openalex.org/W2574750751","https://openalex.org/W2581656816","https://openalex.org/W2595129267","https://openalex.org/W2608549666","https://openalex.org/W2673475642","https://openalex.org/W2752710654","https://openalex.org/W2761307490","https://openalex.org/W2771937410","https://openalex.org/W2899438061","https://openalex.org/W2963728157","https://openalex.org/W2970876363","https://openalex.org/W2982046389","https://openalex.org/W2995737061","https://openalex.org/W2997199111","https://openalex.org/W3035909120","https://openalex.org/W6771936159"],"related_works":["https://openalex.org/W3157244191","https://openalex.org/W4361283779","https://openalex.org/W2066459637","https://openalex.org/W1988784801","https://openalex.org/W1991750263","https://openalex.org/W4225149236","https://openalex.org/W2013980844","https://openalex.org/W3041384410","https://openalex.org/W3205983928","https://openalex.org/W2375178259"],"abstract_inverted_index":{"Aerosolized":[0],"drug":[1,157,197,230,258],"inhalation":[2],"plays":[3],"an":[4,67,80],"important":[5],"role":[6],"in":[7,17,19,22,32,57,74,94,125,152,176,200,212,260],"the":[8,15,27,33,47,51,58,70,75,85,95,99,118,126,133,162,166,181,195,201,237,261],"treatment":[9],"of":[10,14,29,50,69,87,98,142,168,180,236],"respiratory":[11,35],"diseases.":[12],"All":[13],"published":[16],"silico,":[18],"vivo,":[20],"and":[21,43,117,147,249],"vitro":[23],"studies":[24],"have":[25],"improved":[26],"knowledge":[28],"aerosol":[30],"delivery":[31,231],"human":[34,52,138],"system.":[36],"However,":[37],"aerosolized":[38,91,156],"magnetic":[39,71,82,170,196,215],"nano-particle":[40,72,92,135,208],"(MNP)":[41],"transport":[42],"deposition":[44,209],"(TD)":[45],"for":[46,84,220,228],"specific":[48,96,234],"position":[49,97,164,217],"lung":[53,100,183,238],"are":[54,123,150,159],"still":[55],"unavailable":[56],"literature.":[59],"Therefore,":[60],"this":[61,153],"study":[62],"is":[63,174,190,218],"aimed":[64],"to":[65,131,161,193,232,256],"provide":[66],"understanding":[68],"TD":[73,93],"targeted":[76,134,163,229],"region":[77,235],"by":[78,105],"imposing":[79],"external":[81,169],"field":[83,216],"development":[86],"future":[88],"therapeutics.":[89],"Uniform":[90],"airways":[101],"will":[102,245,250],"be":[103,226,247],"modelled":[104],"adopting":[106],"turbulence":[107],"k\u2013\u03c9":[108],"low":[109],"Reynolds":[110],"number":[111],"simulation.":[112],"The":[113,137,155,203],"Euler\u2013Lagrange":[114],"(E\u2013L)":[115],"approach":[116],"magneto":[119],"hydrodynamics":[120],"(MHD)":[121],"model":[122,189],"incorporated":[124],"ANSYS":[127],"fluent":[128],"(18.0)":[129],"solver":[130],"investigate":[132],"TD.":[136],"physical":[139,222],"activity":[140,146],"conditions":[141],"sleeping,":[143],"resting,":[144],"light":[145],"fast":[148],"breathing":[149],"considered":[151],"study.":[154],"particles":[158],"navigated":[160],"under":[165],"influence":[167],"force":[171],"(EMF),":[172],"which":[173,224],"applied":[175],"two":[177,213],"different":[178,214,219],"positions":[179],"two-generation":[182],"airways.":[184],"A":[185],"numerical":[186,204],"particle":[187],"tracing":[188],"also":[191,246],"developed":[192],"predict":[194],"targeting":[198],"behavior":[199],"lung.":[202,262],"results":[205],"reveal":[206],"that":[207],"efficiency":[210],"(DE)":[211],"various":[221],"activities,":[223],"could":[225],"helpful":[227],"a":[233],"after":[239],"extensive":[240],"clinical":[241],"trials.":[242],"This":[243],"process":[244],"cost-effective":[248],"minimize":[251],"unwanted":[252],"side":[253],"effects":[254],"due":[255],"systemic":[257],"distribution":[259]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4}],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2025-10-10T00:00:00"}