{"id":"https://openalex.org/W4319795444","doi":"https://doi.org/10.3390/a16020076","title":"Machine Learning for Early Outcome Prediction in Septic Patients in the Emergency Department","display_name":"Machine Learning for Early Outcome Prediction in Septic Patients in the Emergency Department","publication_year":2023,"publication_date":"2023-02-01","ids":{"openalex":"https://openalex.org/W4319795444","doi":"https://doi.org/10.3390/a16020076"},"language":"en","primary_location":{"id":"doi:10.3390/a16020076","is_oa":true,"landing_page_url":"https://doi.org/10.3390/a16020076","pdf_url":"https://www.mdpi.com/1999-4893/16/2/76/pdf?version=1675229220","source":{"id":"https://openalex.org/S190629608","display_name":"Algorithms","issn_l":"1999-4893","issn":["1999-4893"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1999-4893/16/2/76/pdf?version=1675229220","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081872852","display_name":"Massimiliano Greco","orcid":"https://orcid.org/0000-0003-1003-4637"},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Massimiliano Greco","raw_affiliation_strings":["Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]},{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","institution_ids":["https://openalex.org/I1339471597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072496961","display_name":"Pier Francesco Caruso","orcid":"https://orcid.org/0000-0002-0839-4396"},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Pier Francesco Caruso","raw_affiliation_strings":["Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]},{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","institution_ids":["https://openalex.org/I1339471597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019200791","display_name":"Sofia Spano","orcid":"https://orcid.org/0000-0001-8556-4937"},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sofia Spano","raw_affiliation_strings":["Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]},{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","institution_ids":["https://openalex.org/I1339471597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023915242","display_name":"Gianluigi Citterio","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianluigi Citterio","raw_affiliation_strings":["Emergency Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Emergency Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021388501","display_name":"Antonio Desai","orcid":"https://orcid.org/0000-0003-4674-4905"},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Desai","raw_affiliation_strings":["Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","Emergency Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","institution_ids":["https://openalex.org/I1339471597"]},{"raw_affiliation_string":"Emergency Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110739361","display_name":"Alberto Molteni","orcid":null},"institutions":[{"id":"https://openalex.org/I4210155699","display_name":"Ospedale Eugenio Morelli","ror":"https://ror.org/0532tps88","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210155699"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alberto Molteni","raw_affiliation_strings":["General Surgery Unit, Ospedale Eugenio Morelli, 23035 Sondalo, Italy"],"affiliations":[{"raw_affiliation_string":"General Surgery Unit, Ospedale Eugenio Morelli, 23035 Sondalo, Italy","institution_ids":["https://openalex.org/I4210155699"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040010624","display_name":"Romina Aceto","orcid":null},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Romina Aceto","raw_affiliation_strings":["Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003410133","display_name":"Elena Costantini","orcid":"https://orcid.org/0000-0002-5452-7647"},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elena Costantini","raw_affiliation_strings":["Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071432733","display_name":"Antonio Voza","orcid":"https://orcid.org/0000-0001-7309-6929"},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Voza","raw_affiliation_strings":["Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","Emergency Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","institution_ids":["https://openalex.org/I1339471597"]},{"raw_affiliation_string":"Emergency Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086871368","display_name":"Maurizio Cecconi","orcid":"https://orcid.org/0000-0002-4376-6538"},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maurizio Cecconi","raw_affiliation_strings":["Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]},{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy","institution_ids":["https://openalex.org/I1339471597"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5081872852"],"corresponding_institution_ids":["https://openalex.org/I1339471597","https://openalex.org/I4210163047"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1515},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1515},"fwci":2.2386,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.89937831,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"16","issue":"2","first_page":"76","last_page":"76"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11186","display_name":"Hydrology and Drought Analysis","score":0.9674000144004822,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.8033775687217712},{"id":"https://openalex.org/keywords/emergency-department","display_name":"Emergency department","score":0.7944278120994568},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.7620149254798889},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.7295506596565247},{"id":"https://openalex.org/keywords/sepsis","display_name":"Sepsis","score":0.6428858041763306},{"id":"https://openalex.org/keywords/septic-shock","display_name":"Septic shock","score":0.5951991677284241},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5909085273742676},{"id":"https://openalex.org/keywords/apache-ii","display_name":"APACHE II","score":0.5535542964935303},{"id":"https://openalex.org/keywords/mews","display_name":"Mews","score":0.5032150149345398},{"id":"https://openalex.org/keywords/systemic-inflammatory-response-syndrome","display_name":"Systemic inflammatory response syndrome","score":0.45972082018852234},{"id":"https://openalex.org/keywords/emergency-medicine","display_name":"Emergency medicine","score":0.43193167448043823},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37391555309295654},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.34290391206741333},{"id":"https://openalex.org/keywords/early-warning-score","display_name":"Early warning score","score":0.21172991394996643},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.13805612921714783},{"id":"https://openalex.org/keywords/intensive-care-unit","display_name":"Intensive care unit","score":0.10894328355789185}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8033775687217712},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.7944278120994568},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.7620149254798889},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.7295506596565247},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.6428858041763306},{"id":"https://openalex.org/C2777628635","wikidata":"https://www.wikidata.org/wiki/Q1765564","display_name":"Septic shock","level":3,"score":0.5951991677284241},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5909085273742676},{"id":"https://openalex.org/C2780347030","wikidata":"https://www.wikidata.org/wiki/Q344843","display_name":"APACHE II","level":3,"score":0.5535542964935303},{"id":"https://openalex.org/C2778358025","wikidata":"https://www.wikidata.org/wiki/Q4309761","display_name":"Mews","level":3,"score":0.5032150149345398},{"id":"https://openalex.org/C2781090800","wikidata":"https://www.wikidata.org/wiki/Q776030","display_name":"Systemic inflammatory response syndrome","level":3,"score":0.45972082018852234},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.43193167448043823},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37391555309295654},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34290391206741333},{"id":"https://openalex.org/C2777671062","wikidata":"https://www.wikidata.org/wiki/Q6889402","display_name":"Early warning score","level":2,"score":0.21172991394996643},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.13805612921714783},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.10894328355789185},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/a16020076","is_oa":true,"landing_page_url":"https://doi.org/10.3390/a16020076","pdf_url":"https://www.mdpi.com/1999-4893/16/2/76/pdf?version=1675229220","source":{"id":"https://openalex.org/S190629608","display_name":"Algorithms","issn_l":"1999-4893","issn":["1999-4893"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:82655ca83e6c472fa6273438cffa2a4a","is_oa":true,"landing_page_url":"https://doaj.org/article/82655ca83e6c472fa6273438cffa2a4a","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Algorithms, Vol 16, Iss 2, p 76 (2023)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/1999-4893/16/2/76/","is_oa":true,"landing_page_url":"https://dx.doi.org/10.3390/a16020076","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Algorithms","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/a16020076","is_oa":true,"landing_page_url":"https://doi.org/10.3390/a16020076","pdf_url":"https://www.mdpi.com/1999-4893/16/2/76/pdf?version=1675229220","source":{"id":"https://openalex.org/S190629608","display_name":"Algorithms","issn_l":"1999-4893","issn":["1999-4893"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8799999952316284}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4319795444.pdf"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1511369668","https://openalex.org/W1768679997","https://openalex.org/W1870741591","https://openalex.org/W1898928487","https://openalex.org/W1980034808","https://openalex.org/W1991864206","https://openalex.org/W1995887867","https://openalex.org/W2049927822","https://openalex.org/W2050860153","https://openalex.org/W2064186732","https://openalex.org/W2068316060","https://openalex.org/W2087203965","https://openalex.org/W2101082552","https://openalex.org/W2101234009","https://openalex.org/W2126575308","https://openalex.org/W2129203245","https://openalex.org/W2148143831","https://openalex.org/W2155158241","https://openalex.org/W2165721969","https://openalex.org/W2280404143","https://openalex.org/W2287692495","https://openalex.org/W2313314302","https://openalex.org/W2331591468","https://openalex.org/W2334832924","https://openalex.org/W2397504987","https://openalex.org/W2581766282","https://openalex.org/W2623788409","https://openalex.org/W2724920464","https://openalex.org/W2766207659","https://openalex.org/W2786635213","https://openalex.org/W2899765933","https://openalex.org/W2911964244","https://openalex.org/W2923432641","https://openalex.org/W2929153491","https://openalex.org/W2967525737","https://openalex.org/W2987952249","https://openalex.org/W2999615587","https://openalex.org/W3011115476","https://openalex.org/W3023757607","https://openalex.org/W3136666665","https://openalex.org/W3178131720","https://openalex.org/W4237818622","https://openalex.org/W4251024967","https://openalex.org/W4281785387","https://openalex.org/W4285810567","https://openalex.org/W4290466552","https://openalex.org/W4293242440","https://openalex.org/W6675354045","https://openalex.org/W6784603758"],"related_works":["https://openalex.org/W2112825786","https://openalex.org/W3096994278","https://openalex.org/W2377203086","https://openalex.org/W3031431598","https://openalex.org/W2359121238","https://openalex.org/W2522105146","https://openalex.org/W2903974063","https://openalex.org/W2598298581","https://openalex.org/W2332757436","https://openalex.org/W2116710500"],"abstract_inverted_index":{"Background:":[0],"Sepsis":[1],"is":[2,12,28],"one":[3],"of":[4,8,24,41,183,250,256],"the":[5,18,243,254],"major":[6,204],"causes":[7],"in-hospital":[9],"death,":[10],"and":[11,39,52,63,85,95,125,129,132,139,160,174,193,200,220,248],"frequent":[13],"in":[14,91,162,223,242],"patients":[15,27,68,94,105,148,163,180,226],"presenting":[16],"to":[17,81,107,123,136,260],"emergency":[19],"department":[20],"(ED).":[21],"Early":[22],"identification":[23,38,58],"high-risk":[25],"septic":[26,43,92,104,225],"critical.":[29],"Machine":[30,235],"learning":[31,236],"(ML)":[32],"techniques":[33],"have":[34],"been":[35],"proposed":[36],"for":[37,65,153],"prognostication":[40],"ED":[42,93,108],"patients,":[44],"but":[45],"these":[46],"models":[47,88,188,213,237],"often":[48],"lack":[49,53],"pre-hospital":[50],"data":[51],"validation":[54],"against":[55],"early":[56],"sepsis":[57,147,154],"scores":[59,64],"(such":[60],"as":[61],"qSOFA)":[62],"critically":[66],"ill":[67],"(SOFA,":[69],"APACHE":[70,140,191,221],"II).":[71],"Methods":[72],"We":[73,114,144,208],"conducted":[74],"an":[75],"electronic":[76],"health":[77],"record":[78],"(EHR)":[79],"study":[80],"test":[82],"whether":[83],"interpretable":[84],"scalable":[86],"ML":[87,116,187],"predict":[89],"mortality":[90,157,184,205,229],"compared":[96,133,259],"their":[97,134],"performance":[98,135],"with":[99,245],"clinical":[100],"scores.":[101,142,195],"Consecutive":[102],"adult":[103],"admitted":[106],"over":[109],"18":[110],"months":[111],"were":[112,203],"included.":[113],"built":[115],"models,":[117,216],"ranging":[118],"from":[119,165],"a":[120],"simple-classifier":[121],"model,":[122],"unbalanced":[124,175],"balanced":[126,172],"logistic":[127,176],"regression,":[128],"random":[130,211],"forest,":[131,170],"qSOFA,":[137,190,218],"SOFA,":[138,219],"II":[141],"Results:":[143],"included":[145],"425":[146],"after":[149],"screening":[150],"38,500":[151],"EHR":[152,251],"criteria.":[155],"Overall":[156],"was":[158],"15.2%":[159],"peaked":[161],"coming":[164],"retirement":[166],"homes":[167],"(38%).":[168],"Random":[169],"like":[171],"(0.811)":[173],"regression":[177],"(0.863),":[178],"identified":[179],"at":[181,227],"risk":[182],"(0.813).":[185],"All":[186],"outperformed":[189],"II,":[192,222],"SOFA":[194],"Age,":[196],"mean":[197],"arterial":[198],"pressure,":[199],"serum":[201],"sodium":[202],"predictors.":[206],"Conclusions:":[207],"confirmed":[209],"that":[210],"forest":[212],"outperform":[214],"previous":[215],"including":[217],"identifying":[224],"higher":[228],"risk,":[230],"while":[231],"maintaining":[232],"good":[233],"interpretability.":[234],"may":[238],"gain":[239],"further":[240],"adoption":[241],"future":[244],"increasing":[246],"diffusion":[247],"granularity":[249],"data,":[252],"yielding":[253],"advantage":[255],"increased":[257],"scalability":[258],"standard":[261],"statistical":[262],"techniques.":[263]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1}],"updated_date":"2026-04-14T08:04:32.555800","created_date":"2025-10-10T00:00:00"}