{"id":"https://openalex.org/W4417221370","doi":"https://doi.org/10.3389/fninf.2025.1668395","title":"Assessing the eligibility of Brainomix e-ASPECTS for acute stroke imaging","display_name":"Assessing the eligibility of Brainomix e-ASPECTS for acute stroke imaging","publication_year":2025,"publication_date":"2025-12-11","ids":{"openalex":"https://openalex.org/W4417221370","doi":"https://doi.org/10.3389/fninf.2025.1668395","pmid":"https://pubmed.ncbi.nlm.nih.gov/41458292"},"language":"en","primary_location":{"id":"doi:10.3389/fninf.2025.1668395","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2025.1668395","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2025.1668395/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://public-pages-files-2025.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2025.1668395/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092545828","display_name":"Mateusz Dorochowicz","orcid":"https://orcid.org/0009-0000-0730-6123"},"institutions":[{"id":"https://openalex.org/I11923345","display_name":"Wroc\u0142aw University of Science and Technology","ror":"https://ror.org/008fyn775","country_code":"PL","type":"education","lineage":["https://openalex.org/I11923345"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Mateusz Dorochowicz","raw_affiliation_strings":["Department of General, Interventional and Neuroradiology, Wroclaw University Hospital, Wroc\u0142aw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Interventional and Neuroradiology, Wroclaw University Hospital, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I11923345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079956852","display_name":"Arkadiusz Kaca\u0142a","orcid":"https://orcid.org/0000-0003-2392-6466"},"institutions":[{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Arkadiusz Kaca\u0142a","raw_affiliation_strings":["Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland","Department of Radiology, Wroclaw Medical University, Wroclaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I385303915"]},{"raw_affiliation_string":"Department of Radiology, Wroclaw Medical University, Wroclaw, Poland","institution_ids":["https://openalex.org/I385303915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092632123","display_name":"Micha\u0142 Pu\u0142a","orcid":"https://orcid.org/0000-0002-3265-7424"},"institutions":[{"id":"https://openalex.org/I11923345","display_name":"Wroc\u0142aw University of Science and Technology","ror":"https://ror.org/008fyn775","country_code":"PL","type":"education","lineage":["https://openalex.org/I11923345"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Micha\u0142 Pu\u0142a","raw_affiliation_strings":["Department of General, Interventional and Neuroradiology, Wroclaw University Hospital, Wroc\u0142aw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Interventional and Neuroradiology, Wroclaw University Hospital, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I11923345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045564915","display_name":"Adrian Korbecki","orcid":"https://orcid.org/0000-0003-0047-9819"},"institutions":[{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Adrian Korbecki","raw_affiliation_strings":["Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I385303915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120765077","display_name":"Aleksandra Kosikowska","orcid":null},"institutions":[{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Aleksandra Kosikowska","raw_affiliation_strings":["Faculty of Medicine, Wroclaw Medical University, Wroc\u0142aw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Wroclaw Medical University, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I385303915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120765078","display_name":"Aleksandra To\u0142kacz","orcid":null},"institutions":[{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Aleksandra To\u0142kacz","raw_affiliation_strings":["Faculty of Medicine, Wroclaw Medical University, Wroc\u0142aw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Wroclaw Medical University, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I385303915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075056750","display_name":"Anna Zimny","orcid":"https://orcid.org/0000-0001-6214-0322"},"institutions":[{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Anna Zimny","raw_affiliation_strings":["Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland","Department of Radiology, Wroclaw Medical University, Wroclaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I385303915"]},{"raw_affiliation_string":"Department of Radiology, Wroclaw Medical University, Wroclaw, Poland","institution_ids":["https://openalex.org/I385303915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031330383","display_name":"Maciej Guzi\u0144ski","orcid":"https://orcid.org/0000-0002-9781-2114"},"institutions":[{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Maciej Guzi\u0144ski","raw_affiliation_strings":["Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland","Department of Radiology, Wroclaw Medical University, Wroclaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Interventional and Neuroradiology, Wroclaw Medical University, Wroc\u0142aw, Poland","institution_ids":["https://openalex.org/I385303915"]},{"raw_affiliation_string":"Department of Radiology, Wroclaw Medical University, Wroclaw, Poland","institution_ids":["https://openalex.org/I385303915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5092545828"],"corresponding_institution_ids":["https://openalex.org/I11923345"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":1.0725,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.83651724,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"19","issue":null,"first_page":"1668395","last_page":"1668395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.2712000012397766,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.2712000012397766,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.24400000274181366,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11894","display_name":"Radiology practices and education","score":0.12919999659061432,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-stroke","display_name":"Acute stroke","score":0.8521000146865845},{"id":"https://openalex.org/keywords/radiological-weapon","display_name":"Radiological weapon","score":0.7085000276565552},{"id":"https://openalex.org/keywords/stroke","display_name":"Stroke (engine)","score":0.5271999835968018},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.390500009059906},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.36970001459121704},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.3506999909877777}],"concepts":[{"id":"https://openalex.org/C3020166492","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Acute stroke","level":3,"score":0.8521000146865845},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7802000045776367},{"id":"https://openalex.org/C190892606","wikidata":"https://www.wikidata.org/wiki/Q3512464","display_name":"Radiological weapon","level":2,"score":0.7085000276565552},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5271999835968018},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.47510001063346863},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.390500009059906},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.36970001459121704},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3506999909877777},{"id":"https://openalex.org/C2994024180","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Radiological imaging","level":2,"score":0.3440000116825104},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.3352999985218048},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3312999904155731},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3215000033378601},{"id":"https://openalex.org/C58328972","wikidata":"https://www.wikidata.org/wiki/Q184609","display_name":"Expert system","level":2,"score":0.2971000075340271},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.26080000400543213},{"id":"https://openalex.org/C82157600","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic test","level":2,"score":0.25600001215934753},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.25209999084472656}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fninf.2025.1668395","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2025.1668395","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2025.1668395/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},{"id":"pmid:41458292","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41458292","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neuroinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:ae0ad1f849ae46859d0a22e3186b40cd","is_oa":true,"landing_page_url":"https://doaj.org/article/ae0ad1f849ae46859d0a22e3186b40cd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neuroinformatics, Vol 19 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12738961","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12738961/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Neuroinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fninf.2025.1668395","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2025.1668395","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2025.1668395/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4417221370.pdf","grobid_xml":"https://content.openalex.org/works/W4417221370.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W2019002603","https://openalex.org/W2082775638","https://openalex.org/W2121854361","https://openalex.org/W2143237216","https://openalex.org/W2148656951","https://openalex.org/W2171058244","https://openalex.org/W2427926431","https://openalex.org/W2558092854","https://openalex.org/W2613693561","https://openalex.org/W2623455701","https://openalex.org/W2694557976","https://openalex.org/W2804246295","https://openalex.org/W2885067380","https://openalex.org/W2889969626","https://openalex.org/W2918164910","https://openalex.org/W2944368339","https://openalex.org/W2995945739","https://openalex.org/W3005089753","https://openalex.org/W3022142852","https://openalex.org/W3036167077","https://openalex.org/W3153843819","https://openalex.org/W4210897413","https://openalex.org/W4229036772","https://openalex.org/W4287921920","https://openalex.org/W4294308186","https://openalex.org/W4310795021","https://openalex.org/W4311668674","https://openalex.org/W4319812352","https://openalex.org/W4319826361","https://openalex.org/W4377142653","https://openalex.org/W4388539569","https://openalex.org/W4390102069"],"related_works":[],"abstract_inverted_index":{"Background:":[0],"Timely":[1],"and":[2,56,67,102,122,147,163,184,218],"accurate":[3],"assessment":[4],"of":[5,70,80,182,210],"acute":[6,86,134,235],"ischemic":[7,33,87],"stroke":[8,236],"is":[9,25,42,49],"crucial":[10],"for":[11,14,30,84,192],"determining":[12],"eligibility":[13,194],"mechanical":[15],"thrombectomy.":[16],"The":[17,154,203],"Alberta":[18],"Stroke":[19],"Program":[20],"Early":[21],"CT":[22,37],"Score":[23,173],"(ASPECTS)":[24],"a":[26,185,206,229],"widely":[27],"used":[28],"tool":[29,233],"evaluating":[31],"early":[32],"changes":[34],"on":[35],"non-contrast":[36],"(NCCT),":[38],"but":[39],"its":[40,226,239],"interpretation":[41],"subject":[43],"to":[44,54,62,109],"interobserver":[45],"variability.":[46],"Brainomix":[47,72],"e-ASPECTS":[48,73,105],"an":[50,76],"automated":[51],"software":[52,74,204],"designed":[53],"standardize":[55],"expedite":[57],"this":[58],"assessment.":[59],"We":[60,90],"aimed":[61],"evaluate":[63],"the":[64,71,115,164],"clinical":[65],"utility":[66],"diagnostic":[68,216],"performance":[69],"in":[75,180,189,199,234,248],"unselected,":[77],"real-world":[78],"cohort":[79],"patients":[81,98,249],"undergoing":[82],"NCCT":[83,94],"suspected":[85],"stroke.":[88],"Methods:":[89],"retrospectively":[91],"analyzed":[92],"1,029":[93],"studies":[95],"from":[96],"954":[97],"between":[99,124],"March":[100],"2020":[101],"December":[103],"2024.":[104],"scores":[106],"were":[107,127],"compared":[108],"radiologist-assigned":[110],"ASPECTS,":[111],"which":[112],"served":[113],"as":[114,228],"reference":[116],"standard.":[117],"Diagnostic":[118],"accuracy,":[119],"sensitivity,":[120],"specificity,":[121],"correlation":[123],"scoring":[125],"methods":[126],"assessed.":[128],"Results:":[129],"<":[130,196],"0.001).":[131],"For":[132],"detecting":[133],"ischemia,":[135],"sensitivity":[136],"was":[137,158,168,175],"95.8%":[138],"(95%":[139,144,151,160,170],"CI,":[140,145,152,161,171],"93.6-97.3%),":[141],"specificity":[142],"96.9%":[143],"94.7-98.2%),":[146],"overall":[148],"accuracy":[149,217],"96.3%":[150],"95.1-97.5%).":[153],"positive":[155],"predictive":[156,166],"value":[157,167],"97.2%":[159],"95.3-98.4%),":[162],"negative":[165],"95.3%":[169],"92.8-96.9%).":[172],"concordance":[174],"high,":[176],"with":[177,221,250],"exact":[178],"matches":[179],"92.3%":[181],"cases":[183,201],"\u2264":[186],"1-point":[187],"difference":[188],"97.7%.":[190],"Misclassification":[191],"thrombectomy":[193],"(ASPECTS":[195],"6)":[197],"occurred":[198],"four":[200],"(0.4%).":[202],"achieved":[205],"processing":[207],"success":[208],"rate":[209],"91.9%.":[211],"Conclusion:":[212],"E-ASPECTS":[213],"demonstrates":[214],"high":[215],"strong":[219],"agreement":[220],"expert":[222,245],"radiological":[223],"assessment,":[224],"supporting":[225],"role":[227],"valuable":[230],"decision":[231],"support":[232],"imaging.":[237],"However,":[238],"use":[240],"should":[241],"complement,":[242],"not":[243],"replace,":[244],"interpretation,":[246],"particularly":[247],"low":[251],"ASPECTS":[252],"scores,":[253],"where":[254],"treatment":[255],"decisions":[256],"are":[257],"most":[258],"sensitive.":[259]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-12-11T00:00:00"}