{"id":"https://openalex.org/W4290097542","doi":"https://doi.org/10.3389/fninf.2022.891234","title":"A generalized deep learning network for fractional anisotropy reconstruction: Application to epilepsy and multiple sclerosis","display_name":"A generalized deep learning network for fractional anisotropy reconstruction: Application to epilepsy and multiple sclerosis","publication_year":2022,"publication_date":"2022-08-05","ids":{"openalex":"https://openalex.org/W4290097542","doi":"https://doi.org/10.3389/fninf.2022.891234","pmid":"https://pubmed.ncbi.nlm.nih.gov/35991288"},"language":"en","primary_location":{"id":"doi:10.3389/fninf.2022.891234","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2022.891234","pdf_url":"https://www.frontiersin.org/articles/10.3389/fninf.2022.891234/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fninf.2022.891234/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048749356","display_name":"Marta Gaviraghi","orcid":"https://orcid.org/0000-0001-7427-845X"},"institutions":[{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Marta Gaviraghi","raw_affiliation_strings":["Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103001564","display_name":"Antonio Ricciardi","orcid":"https://orcid.org/0009-0001-7461-051X"},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Antonio Ricciardi","raw_affiliation_strings":["NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014552492","display_name":"Fulvia Palesi","orcid":"https://orcid.org/0000-0001-5027-8770"},"institutions":[{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fulvia Palesi","raw_affiliation_strings":["Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069134946","display_name":"Wallace Brownlee","orcid":"https://orcid.org/0000-0003-0481-8902"},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Wallace Brownlee","raw_affiliation_strings":["NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102804025","display_name":"Paolo Vitali","orcid":"https://orcid.org/0000-0001-9204-2678"},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210099239","display_name":"IRCCS Policlinico San Donato","ror":"https://ror.org/01220jp31","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210099239","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Vitali","raw_affiliation_strings":["Department of Biomedical Sciences for Health, Universit\u00e1 degli Studi di Milano, Milan, Italy","Department of Radiology, IRCCS Policlinico San Donato, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences for Health, Universit\u00e1 degli Studi di Milano, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Department of Radiology, IRCCS Policlinico San Donato, Milan, Italy","institution_ids":["https://openalex.org/I4210099239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054815949","display_name":"Ferr\u00e1n Prados","orcid":"https://orcid.org/0000-0002-7872-0142"},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I138847295","display_name":"Universitat Oberta de Catalunya","ror":"https://ror.org/01f5wp925","country_code":"ES","type":"education","lineage":["https://openalex.org/I138847295"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]}],"countries":["ES","GB"],"is_corresponding":false,"raw_author_name":"Ferran Prados","raw_affiliation_strings":["Department of Medical Physics and Bioengineering, Centre for Medical Image Computing (CMIC), University College London, London, United Kingdom","E-Health Center, Universitat Oberta de Catalunya, Barcelona, Spain","NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Medical Physics and Bioengineering, Centre for Medical Image Computing (CMIC), University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"E-Health Center, Universitat Oberta de Catalunya, Barcelona, Spain","institution_ids":["https://openalex.org/I138847295"]},{"raw_affiliation_string":"NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069328602","display_name":"Baris Kanber","orcid":"https://orcid.org/0000-0003-2443-8800"},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Baris Kanber","raw_affiliation_strings":["NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253","https://openalex.org/I166337079"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037442059","display_name":"Claudia A. M. Gandini Wheeler\u2010Kingshott","orcid":"https://orcid.org/0000-0002-4832-1300"},"institutions":[{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]}],"countries":["GB","IT"],"is_corresponding":false,"raw_author_name":"Claudia A. M. Gandini Wheeler-Kingshott","raw_affiliation_strings":["Brain Connectivity Centre, IRCCS Mondino Foundation, Pavia, Italy","Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy","NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Brain Connectivity Centre, IRCCS Mondino Foundation, Pavia, Italy","institution_ids":[]},{"raw_affiliation_string":"Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy","institution_ids":["https://openalex.org/I25217355"]},{"raw_affiliation_string":"NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253","https://openalex.org/I166337079"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5048749356"],"corresponding_institution_ids":["https://openalex.org/I25217355"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.4292,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.60596885,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"16","issue":null,"first_page":"891234","last_page":"891234"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.994700014591217,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fractional-anisotropy","display_name":"Fractional anisotropy","score":0.7030642628669739},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6280115842819214},{"id":"https://openalex.org/keywords/ground-truth","display_name":"Ground truth","score":0.6130268573760986},{"id":"https://openalex.org/keywords/connectome","display_name":"Connectome","score":0.5625426769256592},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.536784827709198},{"id":"https://openalex.org/keywords/generalization","display_name":"Generalization","score":0.5220144391059875},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.5127094984054565},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5080547332763672},{"id":"https://openalex.org/keywords/human-connectome-project","display_name":"Human Connectome Project","score":0.46835508942604065},{"id":"https://openalex.org/keywords/test-set","display_name":"Test set","score":0.4145851731300354},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4117295742034912},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.24817457795143127},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.19376522302627563},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.16634148359298706},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.15358364582061768},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.14387083053588867},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.14095035195350647}],"concepts":[{"id":"https://openalex.org/C89916169","wikidata":"https://www.wikidata.org/wiki/Q17014600","display_name":"Fractional anisotropy","level":4,"score":0.7030642628669739},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6280115842819214},{"id":"https://openalex.org/C146849305","wikidata":"https://www.wikidata.org/wiki/Q370766","display_name":"Ground truth","level":2,"score":0.6130268573760986},{"id":"https://openalex.org/C45715564","wikidata":"https://www.wikidata.org/wiki/Q1292103","display_name":"Connectome","level":3,"score":0.5625426769256592},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.536784827709198},{"id":"https://openalex.org/C177148314","wikidata":"https://www.wikidata.org/wiki/Q170084","display_name":"Generalization","level":2,"score":0.5220144391059875},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5127094984054565},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5080547332763672},{"id":"https://openalex.org/C97820695","wikidata":"https://www.wikidata.org/wiki/Q387749","display_name":"Human Connectome Project","level":3,"score":0.46835508942604065},{"id":"https://openalex.org/C169903167","wikidata":"https://www.wikidata.org/wiki/Q3985153","display_name":"Test set","level":2,"score":0.4145851731300354},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4117295742034912},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.24817457795143127},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.19376522302627563},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16634148359298706},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.15358364582061768},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.14387083053588867},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.14095035195350647},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fninf.2022.891234","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2022.891234","pdf_url":"https://www.frontiersin.org/articles/10.3389/fninf.2022.891234/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},{"id":"pmid:35991288","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35991288","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neuroinformatics","raw_type":null},{"id":"pmh:oai:air.unimi.it:2434/968200","is_oa":true,"landing_page_url":"https://hdl.handle.net/2434/968200","pdf_url":null,"source":{"id":"https://openalex.org/S4306400516","display_name":"Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I189158943","host_organization_name":"University of Milan","host_organization_lineage":["https://openalex.org/I189158943"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:81f5fac28ec5410a869bbdb8561ad72c","is_oa":true,"landing_page_url":"https://doaj.org/article/81f5fac28ec5410a869bbdb8561ad72c","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neuroinformatics, Vol 16 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9390860","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9390860","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Neuroinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fninf.2022.891234","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2022.891234","pdf_url":"https://www.frontiersin.org/articles/10.3389/fninf.2022.891234/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/4","score":0.44999998807907104,"display_name":"Quality Education"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4290097542.pdf","grobid_xml":"https://content.openalex.org/works/W4290097542.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W605444252","https://openalex.org/W1522301498","https://openalex.org/W1545733638","https://openalex.org/W1555369097","https://openalex.org/W1836465849","https://openalex.org/W1901129140","https://openalex.org/W1937685447","https://openalex.org/W1964802316","https://openalex.org/W1970936375","https://openalex.org/W1983112713","https://openalex.org/W2004006028","https://openalex.org/W2020028069","https://openalex.org/W2024729467","https://openalex.org/W2026812901","https://openalex.org/W2032936392","https://openalex.org/W2051046938","https://openalex.org/W2052644075","https://openalex.org/W2059685157","https://openalex.org/W2062226341","https://openalex.org/W2081520941","https://openalex.org/W2094269283","https://openalex.org/W2101895678","https://openalex.org/W2108243930","https://openalex.org/W2109485534","https://openalex.org/W2133665775","https://openalex.org/W2142059961","https://openalex.org/W2148726987","https://openalex.org/W2156387975","https://openalex.org/W2157766167","https://openalex.org/W2328247767","https://openalex.org/W2505424169","https://openalex.org/W2591999117","https://openalex.org/W2784037480","https://openalex.org/W2790520551","https://openalex.org/W2887206520","https://openalex.org/W2932672475","https://openalex.org/W2947522031","https://openalex.org/W2950030754","https://openalex.org/W2950336490","https://openalex.org/W2962793481","https://openalex.org/W2963073614","https://openalex.org/W2963959597","https://openalex.org/W2970898057","https://openalex.org/W3045737373","https://openalex.org/W3080483662","https://openalex.org/W3096732628","https://openalex.org/W3213532398","https://openalex.org/W4206774419","https://openalex.org/W4226517154","https://openalex.org/W4229062620","https://openalex.org/W4235770099","https://openalex.org/W6680017387","https://openalex.org/W6726983090"],"related_works":["https://openalex.org/W3136590534","https://openalex.org/W3082461017","https://openalex.org/W4280586040","https://openalex.org/W4298370694","https://openalex.org/W2953385226","https://openalex.org/W4306360841","https://openalex.org/W4323359826","https://openalex.org/W2523870064","https://openalex.org/W3126842272","https://openalex.org/W3117051909"],"abstract_inverted_index":{"Fractional":[0],"anisotropy":[1],"(FA)":[2],"is":[3,17,29,90,351],"a":[4,310,318],"quantitative":[5],"map":[6,28,105],"sensitive":[7],"to":[8,20,64,68,92,134,149,154,170,175,181,196,302,314,333],"microstructural":[9,234],"properties":[10],"of":[11,55,95,97,131,275,321,340],"tissues":[12],"<i>in":[13],"vivo</i>":[14],"and":[15,24,37,47,67,103,179,187,262,345],"it":[16],"extensively":[18],"used":[19],"study":[21],"the":[22,52,61,93,98,113,116,123,128,141,147,197,201,209,217,221,225,228,232,237,245,249,252,266,270,280,284,294,298,306,338],"healthy":[23],"pathological":[25,348],"brain.":[26],"This":[27],"classically":[30],"calculated":[31,239],"by":[32],"model":[33,335],"fitting":[34],"(standard":[35],"method)":[36],"requires":[38,82],"many":[39],"diffusion":[40,99],"weighted":[41],"(DW)":[42],"images":[43],"for":[44,354],"data":[45,121,330],"quality":[46,71,106,109,178,331],"unbiased":[48],"readings,":[49],"hence":[50],"needing":[51],"acquisition":[53],"time":[54],"several":[56],"minutes.":[57],"Here,":[58],"we":[59,145],"adapted":[60],"U-net":[62],"architecture":[63],"be":[65,150],"generalized":[66],"obtain":[69,315],"good":[70,108],"FA":[72,136,177,202,218,230,238,260,264,287,316,347],"from":[73,204,293,317,342],"DW":[74,85,132,163,206,242,323],"volumes":[75,86,207,243,324],"acquired":[76,157],"in":[77,183,279,326],"1":[78,327],"minute.":[79],"Our":[80],"network":[81,114,148,167,210,229,263,295,299,308],"10":[83,205,322],"input":[84],"(hence":[87,101,107],"fast":[88],"acquisition),":[89],"robust":[91],"direction":[94],"application":[96],"gradients":[100],"generalized),":[102],"preserves/improves":[104],"maps).":[110],"We":[111,139],"trained":[112,146],"on":[115,127,158],"human":[117],"connectome":[118],"project":[119],"(HCP)":[120],"using":[122,208,220,244,291],"standard":[124,222,246],"model-fitting":[125],"method":[126,313],"entire":[129],"set":[130,320],"directions":[133],"extract":[135],"(ground":[137],"truth).":[138],"addressed":[140],"generalization":[142],"problem,":[143],"i.e.,":[144,297],"applicable,":[151],"without":[152],"retraining,":[153],"clinical":[155,173,226,281,355],"datasets":[156,174,282],"different":[159,162,172],"scanners":[160],"with":[161,240,283],"imaging":[164],"protocols.":[165],"The":[166],"was":[168,211],"applied":[169],"two":[171],"assess":[176],"sensitivity":[180,301],"pathology":[182],"temporal":[184],"lobe":[185],"epilepsy":[186],"multiple":[188],"sclerosis,":[189],"respectively.":[190],"For":[191,224],"HCP":[192],"data,":[193,344],"when":[194,290],"compared":[195,332],"ground":[198,258,285],"truth":[199,259,286],"FA,":[200,296],"obtained":[203,219],"significantly":[212],"better":[213],"(<i>p</i>":[214],"<10<sup>-4</sup>)":[215],"than":[216],"pipeline.":[223],"datasets,":[227],"retained":[231,300],"same":[233,267],"characteristics":[235],"as":[236],"all":[241],"method.":[247],"At":[248],"subject":[250],"level,":[251,272],"comparison":[253],"between":[254],"white":[255],"matter":[256],"(WM)":[257],"values":[261,277,292],"showed":[265],"distribution;":[268],"at":[269],"group":[271],"statistical":[273],"differences":[274],"WM":[276],"detected":[278],"were":[288],"reproduced":[289],"pathology.":[303],"In":[304],"conclusion,":[305],"proposed":[307],"provides":[309],"clinically":[311],"available":[312],"generic":[319],"acquirable":[325],"minute,":[328],"augmenting":[329],"direct":[334],"fitting,":[336],"reducing":[337],"possibility":[339],"bias":[341],"sub-sampled":[343],"retaining":[346],"sensitivity,":[349],"which":[350],"very":[352],"attractive":[353],"applications.":[356]},"counts_by_year":[{"year":2024,"cited_by_count":3}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}