{"id":"https://openalex.org/W2063815712","doi":"https://doi.org/10.3389/fninf.2014.00013","title":"ITK: enabling reproducible research and open science","display_name":"ITK: enabling reproducible research and open science","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2063815712","doi":"https://doi.org/10.3389/fninf.2014.00013","mag":"2063815712","pmid":"https://pubmed.ncbi.nlm.nih.gov/24600387"},"language":"en","primary_location":{"id":"doi:10.3389/fninf.2014.00013","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2014.00013","pdf_url":"https://www.frontiersin.org/articles/10.3389/fninf.2014.00013/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fninf.2014.00013/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064472371","display_name":"Matthew McCormick","orcid":"https://orcid.org/0000-0001-9475-3756"},"institutions":[{"id":"https://openalex.org/I74786994","display_name":"Kitware (United States)","ror":"https://ror.org/02s2acn37","country_code":"US","type":"company","lineage":["https://openalex.org/I74786994"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Matthew McCormick","raw_affiliation_strings":["Medical Computing Group, Kitware Inc Clifton Park, NY, USA","Medical Computing Group, Kitware Inc., Clifton Park, NY, USA"],"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware Inc Clifton Park, NY, USA","institution_ids":[]},{"raw_affiliation_string":"Medical Computing Group, Kitware Inc., Clifton Park, NY, USA","institution_ids":["https://openalex.org/I74786994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100338978","display_name":"Xiaoxiao Liu","orcid":"https://orcid.org/0000-0002-5906-264X"},"institutions":[{"id":"https://openalex.org/I74786994","display_name":"Kitware (United States)","ror":"https://ror.org/02s2acn37","country_code":"US","type":"company","lineage":["https://openalex.org/I74786994"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoxiao Liu","raw_affiliation_strings":["Medical Computing Group, Kitware Inc Clifton Park, NY, USA","Medical Computing Group, Kitware Inc., Clifton Park, NY, USA"],"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware Inc Clifton Park, NY, USA","institution_ids":[]},{"raw_affiliation_string":"Medical Computing Group, Kitware Inc., Clifton Park, NY, USA","institution_ids":["https://openalex.org/I74786994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024770277","display_name":"Julien Jomier","orcid":"https://orcid.org/0000-0002-9020-3770"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julien Jomier","raw_affiliation_strings":["Medical Computing Group, Kitware Inc Lyon, France"],"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware Inc Lyon, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049202741","display_name":"Charles Marion","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles Marion","raw_affiliation_strings":["Medical Computing Group, Kitware Inc Lyon, France"],"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware Inc Lyon, France","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039087877","display_name":"Luis Ib\u00e1\u00f1ez","orcid":"https://orcid.org/0000-0001-6993-0001"},"institutions":[{"id":"https://openalex.org/I74786994","display_name":"Kitware (United States)","ror":"https://ror.org/02s2acn37","country_code":"US","type":"company","lineage":["https://openalex.org/I74786994"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luis Ibanez","raw_affiliation_strings":["Medical Computing Group, Kitware Inc Clifton Park, NY, USA","Medical Computing Group, Kitware Inc., Clifton Park, NY, USA"],"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware Inc Clifton Park, NY, USA","institution_ids":[]},{"raw_affiliation_string":"Medical Computing Group, Kitware Inc., Clifton Park, NY, USA","institution_ids":["https://openalex.org/I74786994"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5064472371"],"corresponding_institution_ids":["https://openalex.org/I74786994"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":17.426,"has_fulltext":true,"cited_by_count":375,"citation_normalized_percentile":{"value":0.98968616,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"8","issue":null,"first_page":"13","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12026","display_name":"Explainable Artificial Intelligence (XAI)","score":0.9708999991416931,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.8132854700088501},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7654047012329102},{"id":"https://openalex.org/keywords/field","display_name":"Field (mathematics)","score":0.6047971844673157},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.5606799721717834},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5461401343345642},{"id":"https://openalex.org/keywords/implementation","display_name":"Implementation","score":0.5372125506401062},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.5071711540222168},{"id":"https://openalex.org/keywords/best-practice","display_name":"Best practice","score":0.46991291642189026},{"id":"https://openalex.org/keywords/reproducibility","display_name":"Reproducibility","score":0.4369465112686157},{"id":"https://openalex.org/keywords/test","display_name":"Test (biology)","score":0.4184149205684662}],"concepts":[{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.8132854700088501},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7654047012329102},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.6047971844673157},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.5606799721717834},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5461401343345642},{"id":"https://openalex.org/C26713055","wikidata":"https://www.wikidata.org/wiki/Q245962","display_name":"Implementation","level":2,"score":0.5372125506401062},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.5071711540222168},{"id":"https://openalex.org/C184356942","wikidata":"https://www.wikidata.org/wiki/Q830382","display_name":"Best practice","level":2,"score":0.46991291642189026},{"id":"https://openalex.org/C9893847","wikidata":"https://www.wikidata.org/wiki/Q1425625","display_name":"Reproducibility","level":2,"score":0.4369465112686157},{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.4184149205684662},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fninf.2014.00013","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2014.00013","pdf_url":"https://www.frontiersin.org/articles/10.3389/fninf.2014.00013/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},{"id":"pmid:24600387","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24600387","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neuroinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:0b80b202baaf4f6c83f19090ec536658","is_oa":true,"landing_page_url":"https://doaj.org/article/0b80b202baaf4f6c83f19090ec536658","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neuroinformatics, Vol 8 (2014)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2928018","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3929840","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3929840","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3929840","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Neuroinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fninf.2014.00013","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fninf.2014.00013","pdf_url":"https://www.frontiersin.org/articles/10.3389/fninf.2014.00013/pdf","source":{"id":"https://openalex.org/S179816892","display_name":"Frontiers in Neuroinformatics","issn_l":"1662-5196","issn":["1662-5196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neuroinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9","score":0.6100000143051147}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2063815712.pdf","grobid_xml":"https://content.openalex.org/works/W2063815712.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1559063789","https://openalex.org/W1565693361","https://openalex.org/W1791037351","https://openalex.org/W1808054655","https://openalex.org/W1871578464","https://openalex.org/W1979514964","https://openalex.org/W1987777080","https://openalex.org/W1995054497","https://openalex.org/W2002463857","https://openalex.org/W2011481459","https://openalex.org/W2026616100","https://openalex.org/W2028910924","https://openalex.org/W2031934506","https://openalex.org/W2036318837","https://openalex.org/W2037620269","https://openalex.org/W2041212401","https://openalex.org/W2046069535","https://openalex.org/W2047222578","https://openalex.org/W2048060485","https://openalex.org/W2049546272","https://openalex.org/W2053239079","https://openalex.org/W2056944867","https://openalex.org/W2067833766","https://openalex.org/W2070441922","https://openalex.org/W2073984231","https://openalex.org/W2114224807","https://openalex.org/W2123722473","https://openalex.org/W2129965408","https://openalex.org/W2133287637","https://openalex.org/W2154897810","https://openalex.org/W2167023602","https://openalex.org/W2171078237","https://openalex.org/W2320280844","https://openalex.org/W2334484550","https://openalex.org/W2594075087","https://openalex.org/W2751279003","https://openalex.org/W3127702745","https://openalex.org/W4205177943","https://openalex.org/W4298348354","https://openalex.org/W6633891752","https://openalex.org/W6638091777","https://openalex.org/W6639277066","https://openalex.org/W6653967188","https://openalex.org/W6668768775"],"related_works":["https://openalex.org/W2413717610","https://openalex.org/W1973270181","https://openalex.org/W2417696084","https://openalex.org/W2368782778","https://openalex.org/W2087830269","https://openalex.org/W3106281778","https://openalex.org/W2140154150","https://openalex.org/W638612878","https://openalex.org/W4324138256","https://openalex.org/W2083330954"],"abstract_inverted_index":{"Reproducibility":[0],"verification":[1,225],"is":[2,93],"essential":[3,111],"to":[4,63,75,175,213],"the":[5,8,23,30,64,73,79,87,96,100,120,123,131,139,154,165,182,192,199,208,217,221,254,274],"practice":[6],"of":[7,48,81,95,102,122,158,186,216,269],"scientific":[9,24,32,65,88,184],"method.":[10],"Researchers":[11],"report":[12],"their":[13],"findings,":[14],"which":[15,99,142,174],"are":[16,84,109,145],"strengthened":[17],"as":[18],"other":[19],"independent":[20],"groups":[21],"in":[22,86,98,127,211],"community":[25,168,201],"share":[26],"similar":[27],"outcomes.":[28],"In":[29,117],"many":[31],"fields":[33,97],"where":[34],"software":[35,55,106],"has":[36,129,163,202,256],"become":[37,214],"a":[38,177,267],"fundamental":[39],"tool":[40],"for":[41,113],"capturing":[42],"and":[43,53,57,72,107,133,149,156,196,205],"analyzing":[44],"data,":[45],"this":[46,118],"requirement":[47],"reproducibility":[49,80,187,224],"implies":[50],"that":[51,83,180,198,237],"reliable":[52],"comprehensive":[54],"platforms":[56],"tools":[58,68],"should":[59],"be":[60],"made":[61],"available":[62],"community.":[66],"The":[67,245,262],"will":[69],"empower":[70],"them":[71],"public":[74],"verify,":[76],"through":[77],"practice,":[78],"observations":[82],"reported":[85],"literature.":[89],"Medical":[90],"image":[91,167],"analysis":[92],"one":[94,215],"use":[101],"computational":[103],"resources,":[104],"both":[105],"hardware,":[108],"an":[110,170,248],"platform":[112,172],"performing":[114],"experimental":[115],"work.":[116],"arena,":[119],"introduction":[121],"Insight":[124,246],"Toolkit":[125],"(ITK)":[126],"1999":[128],"transformed":[130],"field":[132],"facilitates":[134],"its":[135],"progress":[136],"by":[137],"accelerating":[138],"rate":[140],"at":[141],"algorithmic":[143],"implementations":[144],"developed,":[146],"tested,":[147],"disseminated":[148],"improved.":[150],"By":[151],"building":[152],"on":[153,173],"efficiency":[155],"quality":[157],"open":[159,249],"source":[160],"methodologies,":[161,195],"ITK":[162,200],"provided":[164],"medical":[166],"with":[169,220,253],"effective":[171],"build":[176],"daily":[178],"workflow":[179],"incorporates":[181],"true":[183],"practices":[185,197],"verification.":[188],"This":[189],"article":[190],"describes":[191],"multiple":[193],"tools,":[194],"adopted,":[203],"refined,":[204],"followed":[206],"during":[207],"past":[209],"decade,":[210],"order":[212],"research":[218],"communities":[219],"most":[222],"modern":[223],"infrastructure.":[226],"For":[227],"example,":[228],"207":[229],"contributors":[230],"have":[231],"created":[232],"over":[233,239,258],"2400":[234],"unit":[235],"tests":[236],"provide":[238],"84%":[240],"code":[241,277],"line":[242],"test":[243],"coverage.":[244],"Journal,":[247],"publication":[250,260],"journal":[251],"associated":[252],"toolkit,":[255],"seen":[257],"360,000":[259],"downloads.":[261],"median":[263],"normalized":[264],"closeness":[265],"centrality,":[266],"measure":[268],"knowledge":[270],"flow,":[271],"resulting":[272],"from":[273],"distributed":[275],"peer":[276],"review":[278],"system":[279],"was":[280],"high,":[281],"0.46.":[282]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":57},{"year":2024,"cited_by_count":65},{"year":2023,"cited_by_count":72},{"year":2022,"cited_by_count":76},{"year":2021,"cited_by_count":49},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2}],"updated_date":"2026-03-13T16:22:10.518609","created_date":"2025-10-10T00:00:00"}