{"id":"https://openalex.org/W7128502213","doi":"https://doi.org/10.3389/fncom.2026.1731868","title":"Shifts in brain dynamics and drivers of consciousness state transitions","display_name":"Shifts in brain dynamics and drivers of consciousness state transitions","publication_year":2026,"publication_date":"2026-02-10","ids":{"openalex":"https://openalex.org/W7128502213","doi":"https://doi.org/10.3389/fncom.2026.1731868","pmid":"https://pubmed.ncbi.nlm.nih.gov/41743844"},"language":"en","primary_location":{"id":"doi:10.3389/fncom.2026.1731868","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2026.1731868","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2026.1731868/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://public-pages-files-2025.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2026.1731868/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112573017","display_name":"Joseph S. Bodenheimer","orcid":null},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joseph Bodenheimer","raw_affiliation_strings":["Department of Psychology, The University of Kansas"],"affiliations":[{"raw_affiliation_string":"Department of Psychology, The University of Kansas","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122904526","display_name":"Paul Bogdan","orcid":null},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Bogdan","raw_affiliation_strings":["Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California"],"affiliations":[{"raw_affiliation_string":"Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040066595","display_name":"S\u00e9rgio Pequito","orcid":"https://orcid.org/0000-0002-5143-1543"},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"S\u00e9rgio Pequito","raw_affiliation_strings":["Institute for Systems and Robotics, Instituto Superior T\u00e9cnico, Universidade de Lisboa"],"affiliations":[{"raw_affiliation_string":"Institute for Systems and Robotics, Instituto Superior T\u00e9cnico, Universidade de Lisboa","institution_ids":["https://openalex.org/I141596103"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5125526071","display_name":"Arian Ashourvan","orcid":null},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arian Ashourvan","raw_affiliation_strings":["Department of Psychology, The University of Kansas"],"affiliations":[{"raw_affiliation_string":"Department of Psychology, The University of Kansas","institution_ids":["https://openalex.org/I146416000"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5112573017"],"corresponding_institution_ids":["https://openalex.org/I146416000"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.54584568,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":null,"first_page":"1731868","last_page":"1731868"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9200999736785889,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9200999736785889,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.009399999864399433,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/consciousness","display_name":"Consciousness","score":0.8485999703407288},{"id":"https://openalex.org/keywords/brain-activity-and-meditation","display_name":"Brain activity and meditation","score":0.5231999754905701},{"id":"https://openalex.org/keywords/neural-correlates-of-consciousness","display_name":"Neural correlates of consciousness","score":0.475600004196167},{"id":"https://openalex.org/keywords/functional-magnetic-resonance-imaging","display_name":"Functional magnetic resonance imaging","score":0.4675999879837036},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.453000009059906},{"id":"https://openalex.org/keywords/stability","display_name":"Stability (learning theory)","score":0.4465000033378601},{"id":"https://openalex.org/keywords/transition","display_name":"Transition (genetics)","score":0.3813999891281128},{"id":"https://openalex.org/keywords/neural-activity","display_name":"Neural activity","score":0.37929999828338623}],"concepts":[{"id":"https://openalex.org/C186720457","wikidata":"https://www.wikidata.org/wiki/Q7087","display_name":"Consciousness","level":2,"score":0.8485999703407288},{"id":"https://openalex.org/C120843803","wikidata":"https://www.wikidata.org/wiki/Q4955807","display_name":"Brain activity and meditation","level":3,"score":0.5231999754905701},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.4902999997138977},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.4772999882698059},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4772000014781952},{"id":"https://openalex.org/C129564537","wikidata":"https://www.wikidata.org/wiki/Q1460873","display_name":"Neural correlates of consciousness","level":3,"score":0.475600004196167},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.4675999879837036},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.453000009059906},{"id":"https://openalex.org/C112972136","wikidata":"https://www.wikidata.org/wiki/Q7595718","display_name":"Stability (learning theory)","level":2,"score":0.4465000033378601},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4458000063896179},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42800000309944153},{"id":"https://openalex.org/C194232998","wikidata":"https://www.wikidata.org/wiki/Q1606712","display_name":"Transition (genetics)","level":3,"score":0.3813999891281128},{"id":"https://openalex.org/C2984127161","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neural activity","level":2,"score":0.37929999828338623},{"id":"https://openalex.org/C1305866","wikidata":"https://www.wikidata.org/wiki/Q4530887","display_name":"Electromagnetic theories of consciousness","level":3,"score":0.3292999863624573},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.30660000443458557},{"id":"https://openalex.org/C79379906","wikidata":"https://www.wikidata.org/wiki/Q3174497","display_name":"Dynamical systems theory","level":2,"score":0.298799991607666},{"id":"https://openalex.org/C2986949344","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Neural system","level":2,"score":0.28999999165534973},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.2865999937057495},{"id":"https://openalex.org/C126701199","wikidata":"https://www.wikidata.org/wiki/Q264224","display_name":"Complex dynamics","level":2,"score":0.2842000126838684},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.2750999927520752},{"id":"https://openalex.org/C47822265","wikidata":"https://www.wikidata.org/wiki/Q854457","display_name":"Complex system","level":2,"score":0.2702000141143799},{"id":"https://openalex.org/C171525899","wikidata":"https://www.wikidata.org/wiki/Q17029618","display_name":"Level of consciousness","level":2,"score":0.26840001344680786},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2556000053882599},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.25110000371932983}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fncom.2026.1731868","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2026.1731868","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2026.1731868/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},{"id":"pmid:41743844","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41743844","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in computational neuroscience","raw_type":null},{"id":"pmh:oai:doaj.org/article:08fb599ee51543ecab86e5331d6c0195","is_oa":true,"landing_page_url":"https://doaj.org/article/08fb599ee51543ecab86e5331d6c0195","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Computational Neuroscience, Vol 20 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12929524","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12929524/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Comput Neurosci","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fncom.2026.1731868","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2026.1731868","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2026.1731868/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7128502213.pdf","grobid_xml":"https://content.openalex.org/works/W7128502213.grobid-xml"},"referenced_works_count":80,"referenced_works":["https://openalex.org/W40392240","https://openalex.org/W1434475215","https://openalex.org/W1502722314","https://openalex.org/W1588401088","https://openalex.org/W1597651850","https://openalex.org/W1963914175","https://openalex.org/W1979155542","https://openalex.org/W1987971958","https://openalex.org/W1988276601","https://openalex.org/W1991825895","https://openalex.org/W1994360736","https://openalex.org/W1999329764","https://openalex.org/W2003452274","https://openalex.org/W2005136695","https://openalex.org/W2009975309","https://openalex.org/W2010741476","https://openalex.org/W2039380096","https://openalex.org/W2047189453","https://openalex.org/W2051224630","https://openalex.org/W2064420997","https://openalex.org/W2069908974","https://openalex.org/W2072827698","https://openalex.org/W2076465743","https://openalex.org/W2085487226","https://openalex.org/W2090687144","https://openalex.org/W2097792392","https://openalex.org/W2097883744","https://openalex.org/W2099231026","https://openalex.org/W2103111465","https://openalex.org/W2110017742","https://openalex.org/W2110065044","https://openalex.org/W2112639978","https://openalex.org/W2117340355","https://openalex.org/W2118706537","https://openalex.org/W2121382938","https://openalex.org/W2124508356","https://openalex.org/W2124953625","https://openalex.org/W2129317350","https://openalex.org/W2133318750","https://openalex.org/W2136573752","https://openalex.org/W2138696501","https://openalex.org/W2138866420","https://openalex.org/W2141461755","https://openalex.org/W2142794733","https://openalex.org/W2150534249","https://openalex.org/W2151511579","https://openalex.org/W2151721316","https://openalex.org/W2151928874","https://openalex.org/W2159388055","https://openalex.org/W2742686471","https://openalex.org/W2750722525","https://openalex.org/W2755099398","https://openalex.org/W2786504149","https://openalex.org/W2791242539","https://openalex.org/W2913125551","https://openalex.org/W2951617899","https://openalex.org/W2951846486","https://openalex.org/W2963303578","https://openalex.org/W2963335520","https://openalex.org/W2963348735","https://openalex.org/W3012472614","https://openalex.org/W3034516253","https://openalex.org/W3085205048","https://openalex.org/W3100142588","https://openalex.org/W3108159844","https://openalex.org/W3136858771","https://openalex.org/W3174100758","https://openalex.org/W3185074371","https://openalex.org/W4224217494","https://openalex.org/W4235770099","https://openalex.org/W4251842747","https://openalex.org/W4286492093","https://openalex.org/W4296323156","https://openalex.org/W4303454044","https://openalex.org/W4308142940","https://openalex.org/W4309630525","https://openalex.org/W4377011049","https://openalex.org/W4388852176","https://openalex.org/W4389564227","https://openalex.org/W4412883517"],"related_works":[],"abstract_inverted_index":{"Understanding":[0],"the":[1,5,21,27,31,76,83,88,134,179],"neural":[2],"mechanisms":[3],"underlying":[4,22],"transitions":[6,93,181],"between":[7,94],"different":[8],"states":[9],"of":[10,24,30,45,79,87,136,192,197],"consciousness":[11,46,95,128,193],"is":[12],"a":[13,56],"fundamental":[14],"challenge":[15],"in":[16,75,141,149,195],"neuroscience.":[17],"Thus,":[18],"we":[19],"investigate":[20],"drivers":[23,105,148,176],"changes":[25,74,146],"during":[26,92,110],"resting-state":[28],"dynamics":[29,174],"human":[32],"brain,":[33],"as":[34,153,178],"captured":[35],"by":[36],"functional":[37],"magnetic":[38],"resonance":[39],"imaging":[40],"(fMRI)":[41],"across":[42,127],"varying":[43],"levels":[44],"(awake,":[47],"light":[48,170],"sedation,":[49,51],"deep":[50],"and":[52,85,147,175],"recovery).":[53],"We":[54],"deploy":[55],"model-based":[57],"approach":[58,132],"relying":[59],"on":[60,171],"linear":[61,163],"time-invariant":[62],"(LTI)":[63],"dynamical":[64],"systems":[65],"under":[66,139],"unknown":[67],"inputs":[68,120],"(UI).":[69],"Our":[70,114],"findings":[71,115,168],"reveal":[72],"distinct":[73],"spectral":[77],"profile":[78],"brain":[80,108,144,180],"dynamics-particularly":[81],"regarding":[82],"stability":[84],"frequency":[86],"system's":[89],"oscillatory":[90],"modes":[91],"states.":[96,129],"These":[97],"models":[98,138],"further":[99],"enable":[100],"us":[101],"to":[102,160],"identify":[103],"external":[104],"influencing":[106],"large-scale":[107,143],"activity":[109],"naturalistic":[111,154],"auditory":[112],"stimulation.":[113],"suggest":[116],"that":[117],"these":[118],"identified":[119],"delineate":[121],"how":[122,172],"stimulus-induced":[123],"co-activity":[124],"propagation":[125],"differs":[126],"Notably,":[130],"our":[131,167],"showcases":[133],"effectiveness":[135],"LTI":[137],"UI":[140],"capturing":[142],"dynamic":[145],"complex":[150],"paradigms,":[151],"such":[152],"stimulation,":[155],"which":[156],"are":[157],"not":[158],"conducive":[159],"conventional":[161],"general":[162],"model":[164],"analysis.":[165],"Importantly,":[166],"shed":[169],"brain-wide":[173],"evolve":[177],"toward":[182],"conscious":[183],"states,":[184],"holding":[185],"promise":[186],"for":[187],"developing":[188],"more":[189],"accurate":[190],"biomarkers":[191],"recovery":[194],"disorders":[196],"consciousness.":[198]},"counts_by_year":[],"updated_date":"2026-03-10T14:07:55.174380","created_date":"2026-02-11T00:00:00"}