{"id":"https://openalex.org/W4402016799","doi":"https://doi.org/10.3389/fncom.2024.1293279","title":"Quantifying network behavior in the rat prefrontal cortex","display_name":"Quantifying network behavior in the rat prefrontal cortex","publication_year":2024,"publication_date":"2024-08-29","ids":{"openalex":"https://openalex.org/W4402016799","doi":"https://doi.org/10.3389/fncom.2024.1293279","pmid":"https://pubmed.ncbi.nlm.nih.gov/39268151"},"language":"en","primary_location":{"id":"doi:10.3389/fncom.2024.1293279","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2024.1293279","pdf_url":"https://www.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2024.1293279/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2024.1293279/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081320285","display_name":"Congzhou M. Sha","orcid":"https://orcid.org/0000-0001-5301-9459"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Congzhou M. Sha","raw_affiliation_strings":["Department of Engineering Science and Mechanics, Penn State University, University Park, PA, United States","Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States"],"affiliations":[{"raw_affiliation_string":"Department of Engineering Science and Mechanics, Penn State University, University Park, PA, United States","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024072185","display_name":"Jian Wang","orcid":"https://orcid.org/0000-0001-7768-2802"},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jian Wang","raw_affiliation_strings":["Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075795856","display_name":"Richard B. Mailman","orcid":null},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Richard B. Mailman","raw_affiliation_strings":["Department of Neurology, Penn State College of Medicine, Hershey, PA, United States","Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States"],"affiliations":[{"raw_affiliation_string":"Department of Neurology, Penn State College of Medicine, Hershey, PA, United States","institution_ids":["https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100397405","display_name":"Yang Yang","orcid":"https://orcid.org/0000-0001-6612-8865"},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yang Yang","raw_affiliation_strings":["Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033490428","display_name":"Nikolay V. Dokholyan","orcid":null},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nikolay V. Dokholyan","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, PA, United States","Department of Biomedical Engineering, Penn State University, University Park, PA, United States","Department of Chemistry, Penn State University, University Park, PA, United States","Department of Engineering Science and Mechanics, Penn State University, University Park, PA, United States","Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, PA, United States","institution_ids":["https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Penn State University, University Park, PA, United States","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Chemistry, Penn State University, University Park, PA, United States","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Engineering Science and Mechanics, Penn State University, University Park, PA, United States","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Pharmacology, Penn State College of Medicine, Hershey, PA, United States","institution_ids":["https://openalex.org/I82783531"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5033490428","https://openalex.org/A5075795856","https://openalex.org/A5100397405"],"corresponding_institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14238978,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":null,"first_page":"1293279","last_page":"1293279"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9793999791145325,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9627000093460083,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"Prefrontal cortex","score":0.7670875787734985},{"id":"https://openalex.org/keywords/local-field-potential","display_name":"Local field potential","score":0.7002296447753906},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6402592062950134},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6308028697967529},{"id":"https://openalex.org/keywords/dynamic-time-warping","display_name":"Dynamic time warping","score":0.5294482707977295},{"id":"https://openalex.org/keywords/working-memory","display_name":"Working memory","score":0.43343034386634827},{"id":"https://openalex.org/keywords/neural-ensemble","display_name":"Neural ensemble","score":0.426582396030426},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.4128556251525879},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.36848050355911255},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.32549354434013367},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3214775025844574},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.31472522020339966}],"concepts":[{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.7670875787734985},{"id":"https://openalex.org/C117838684","wikidata":"https://www.wikidata.org/wiki/Q533483","display_name":"Local field potential","level":2,"score":0.7002296447753906},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6402592062950134},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6308028697967529},{"id":"https://openalex.org/C88516994","wikidata":"https://www.wikidata.org/wiki/Q1268863","display_name":"Dynamic time warping","level":2,"score":0.5294482707977295},{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.43343034386634827},{"id":"https://openalex.org/C187782996","wikidata":"https://www.wikidata.org/wiki/Q9390548","display_name":"Neural ensemble","level":2,"score":0.426582396030426},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.4128556251525879},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.36848050355911255},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.32549354434013367},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3214775025844574},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.31472522020339966}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fncom.2024.1293279","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2024.1293279","pdf_url":"https://www.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2024.1293279/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},{"id":"pmid:39268151","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39268151","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in computational neuroscience","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11390430","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11390430","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11390430/pdf/fncom-18-1293279.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Comput Neurosci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:83905e54997d49a1b9be8ddfcc867164","is_oa":true,"landing_page_url":"https://doaj.org/article/83905e54997d49a1b9be8ddfcc867164","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Computational Neuroscience, Vol 18 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fncom.2024.1293279","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2024.1293279","pdf_url":"https://www.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2024.1293279/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Peace, Justice and strong institutions","score":0.7300000190734863,"id":"https://metadata.un.org/sdg/16"}],"awards":[{"id":"https://openalex.org/G1039481600","display_name":null,"funder_award_id":"1R35 GM134864","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3497591915","display_name":null,"funder_award_id":"(NIH)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4172894125","display_name":null,"funder_award_id":"R01 AT012053","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5233090176","display_name":null,"funder_award_id":"1R01 AT012053","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8296778333","display_name":null,"funder_award_id":"R35 GM134864","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402016799.pdf","grobid_xml":"https://content.openalex.org/works/W4402016799.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W2184293","https://openalex.org/W1596457615","https://openalex.org/W1982077411","https://openalex.org/W1985940938","https://openalex.org/W2000539955","https://openalex.org/W2011301426","https://openalex.org/W2031049446","https://openalex.org/W2075931307","https://openalex.org/W2078993594","https://openalex.org/W2097267381","https://openalex.org/W2104266030","https://openalex.org/W2108367605","https://openalex.org/W2112348586","https://openalex.org/W2120996632","https://openalex.org/W2125782175","https://openalex.org/W2146292423","https://openalex.org/W2151480498","https://openalex.org/W2245964996","https://openalex.org/W2441124914","https://openalex.org/W2521276659","https://openalex.org/W2559748052","https://openalex.org/W2755162731","https://openalex.org/W2886501130","https://openalex.org/W2901906577","https://openalex.org/W2951287344","https://openalex.org/W2954731284","https://openalex.org/W3003257820","https://openalex.org/W3035965352","https://openalex.org/W3080144203","https://openalex.org/W3082033687","https://openalex.org/W3090217273","https://openalex.org/W3099878876","https://openalex.org/W3103145119","https://openalex.org/W3120395234","https://openalex.org/W3150635270","https://openalex.org/W3189386448","https://openalex.org/W3216196091","https://openalex.org/W4220838968","https://openalex.org/W4246219036","https://openalex.org/W4282978482","https://openalex.org/W4323809195","https://openalex.org/W4399585236","https://openalex.org/W6676606992","https://openalex.org/W6682981795"],"related_works":["https://openalex.org/W2027232968","https://openalex.org/W2514944117","https://openalex.org/W1995248718","https://openalex.org/W2762558726","https://openalex.org/W2062215599","https://openalex.org/W4388850725","https://openalex.org/W2474011416","https://openalex.org/W1980451075","https://openalex.org/W2891980675","https://openalex.org/W4232732910"],"abstract_inverted_index":{"The":[0,134,150],"question":[1],"of":[2,24,45,89,99,145,156],"how":[3,37],"consciousness":[4],"and":[5,17,22,26,33,50,60,70,107,120,130,142,159,173,180],"behavior":[6,38],"arise":[7],"from":[8,126],"neural":[9,139],"activity":[10,44],"is":[11,30,39,176],"fundamental":[12],"to":[13,18,41,84,124,137],"understanding":[14],"the":[15,20,42,46,66,76,86,90,96,143,153,160],"brain,":[16],"improving":[19],"diagnosis":[21],"treatment":[23],"neurological":[25],"psychiatric":[27],"disorders.":[28],"There":[29],"significant":[31],"murine":[32],"primate":[34],"literature":[35],"on":[36],"related":[40],"electrophysiological":[43],"medial":[47],"prefrontal":[48,91],"cortex":[49],"its":[51],"role":[52],"in":[53],"working":[54],"memory":[55],"processes":[56,88],"such":[57,100],"as":[58],"planning":[59],"decision-making.":[61],"Existing":[62],"experimental":[63],"designs,":[64],"specifically":[65],"rodent":[67],"spike":[68,128],"train":[69],"local":[71,131],"field":[72,132],"potential":[73],"recordings":[74],"during":[75],"T-maze":[77],"alternation":[78],"task,":[79],"have":[80],"insufficient":[81],"statistical":[82,122,154],"power":[83],"unravel":[85],"complex":[87],"cortex.":[92],"We":[93],"therefore":[94],"examined":[95],"theoretical":[97,113],"limitations":[98,155],"experiments,":[101],"providing":[102],"concrete":[103],"guidelines":[104],"for":[105],"robust":[106],"reproducible":[108],"science.":[109],"To":[110],"approach":[111],"these":[112],"limits,":[114],"we":[115],"applied":[116],"dynamic":[117,167],"time":[118,168],"warping":[119,169],"associated":[121],"tests":[123],"data":[125],"neuron":[127],"trains":[129],"potentials.":[133],"goal":[135],"was":[136],"quantify":[138],"network":[140],"synchronicity":[141],"correlation":[144],"neuroelectrophysiology":[146],"with":[147,170],"rat":[148],"behavior.":[149],"results":[151],"show":[152],"existing":[157],"data,":[158],"fact":[161],"that":[162],"making":[163],"meaningful":[164],"comparison":[165],"between":[166],"traditional":[171],"Fourier":[172],"wavelet":[174],"analysis":[175],"impossible":[177],"until":[178],"larger":[179],"cleaner":[181],"datasets":[182],"are":[183],"available.":[184]},"counts_by_year":[],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}
