{"id":"https://openalex.org/W4381805784","doi":"https://doi.org/10.3389/fncom.2023.1227850","title":"Editorial: Decoding novel therapeutic targets, biomarkers, and drug development strategies against neurodegenerative disorders\u2014A multi-omics approach","display_name":"Editorial: Decoding novel therapeutic targets, biomarkers, and drug development strategies against neurodegenerative disorders\u2014A multi-omics approach","publication_year":2023,"publication_date":"2023-06-22","ids":{"openalex":"https://openalex.org/W4381805784","doi":"https://doi.org/10.3389/fncom.2023.1227850","pmid":"https://pubmed.ncbi.nlm.nih.gov/37426197"},"language":"en","primary_location":{"id":"doi:10.3389/fncom.2023.1227850","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2023.1227850","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncom.2023.1227850/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"type":"editorial","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fncom.2023.1227850/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"E. Srinivasan","orcid":null},"institutions":[{"id":"https://openalex.org/I59270414","display_name":"Indian Institute of Science Bangalore","ror":"https://ror.org/04dese585","country_code":"IN","type":"education","lineage":["https://openalex.org/I59270414"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"E. Srinivasan","raw_affiliation_strings":["Molecular Biophysics Unit, Indian Institute of Science, Bengaluru, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Biophysics Unit, Indian Institute of Science, Bengaluru, India","institution_ids":["https://openalex.org/I59270414"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055057529","display_name":"Siranjeevi Nagaraj","orcid":"https://orcid.org/0000-0001-8132-491X"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Siranjeevi Nagaraj","raw_affiliation_strings":["Laboratory of Histology, Neuropathology and Neuroanatomy, Faculty of Medicine, ULB Neuroscience Institute, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Histology, Neuropathology and Neuroanatomy, Faculty of Medicine, ULB Neuroscience Institute, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium","institution_ids":["https://openalex.org/I132053463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085229724","display_name":"Sakthi Rajendran","orcid":"https://orcid.org/0000-0002-1603-9693"},"institutions":[{"id":"https://openalex.org/I1314135232","display_name":"Nationwide Children's Hospital","ror":"https://ror.org/003rfsp33","country_code":"US","type":"funder","lineage":["https://openalex.org/I1314135232"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sakthi Rajendran","raw_affiliation_strings":["The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, United States","institution_ids":["https://openalex.org/I1314135232"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100628263","display_name":"R. Rajasekaran","orcid":null},"institutions":[{"id":"https://openalex.org/I876193797","display_name":"Vellore Institute of Technology University","ror":"https://ror.org/00qzypv28","country_code":"IN","type":"education","lineage":["https://openalex.org/I876193797"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R. Rajasekaran","raw_affiliation_strings":["Quantitative Biology Lab, Department of Integrative Biology, School of Bio Sciences and Technology, Vellore Institute of Technology (Deemed to be University), Vellore, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Quantitative Biology Lab, Department of Integrative Biology, School of Bio Sciences and Technology, Vellore Institute of Technology (Deemed to be University), Vellore, India","institution_ids":["https://openalex.org/I876193797"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I59270414"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.1735,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.51471565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"17","issue":null,"first_page":"1227850","last_page":"1227850"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9840999841690063,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9840999841690063,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.982699990272522,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.9728999733924866,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5340244770050049},{"id":"https://openalex.org/keywords/drug-development","display_name":"Drug development","score":0.4557305574417114},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.44990453124046326},{"id":"https://openalex.org/keywords/omics","display_name":"Omics","score":0.4140756130218506},{"id":"https://openalex.org/keywords/decoding-methods","display_name":"Decoding methods","score":0.4111586809158325},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.36319947242736816},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3238414525985718},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.22501221299171448},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.20790034532546997},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1947849690914154},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.17855969071388245}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5340244770050049},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.4557305574417114},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.44990453124046326},{"id":"https://openalex.org/C157585117","wikidata":"https://www.wikidata.org/wiki/Q158666","display_name":"Omics","level":2,"score":0.4140756130218506},{"id":"https://openalex.org/C57273362","wikidata":"https://www.wikidata.org/wiki/Q576722","display_name":"Decoding methods","level":2,"score":0.4111586809158325},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.36319947242736816},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3238414525985718},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.22501221299171448},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.20790034532546997},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1947849690914154},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.17855969071388245},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3389/fncom.2023.1227850","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2023.1227850","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncom.2023.1227850/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},{"id":"pmid:37426197","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37426197","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in computational neuroscience","raw_type":null},{"id":"pmh:oai::82602","is_oa":true,"landing_page_url":null,"pdf_url":"https://mpra.ub.uni-muenchen.de/82602/1/MPRA_paper_82602.pdf","source":{"id":"https://openalex.org/S4306401429","display_name":"ePrints@IISc (Indian Institute of Science)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I59270414","host_organization_name":"Indian Institute of Science Bangalore","host_organization_lineage":["https://openalex.org/I59270414"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Editorials/Short Communications"},{"id":"pmh:oai:dipot.ulb.ac.be:2013/371170","is_oa":true,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/371170","pdf_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/371170/1/doi_354814.pdf","source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Computational Neuroscience, 17","raw_type":"info:ulb-repo/semantics/openurl/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10325664","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10325664","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10325664/pdf/fncom-17-1227850.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Comput Neurosci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:f5a645c25af741079b175c7ed25a8935","is_oa":true,"landing_page_url":"https://doaj.org/article/f5a645c25af741079b175c7ed25a8935","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Computational Neuroscience, Vol 17 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fncom.2023.1227850","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2023.1227850","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncom.2023.1227850/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4381805784.pdf","grobid_xml":"https://content.openalex.org/works/W4381805784.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W2898991528","https://openalex.org/W3006225682","https://openalex.org/W3043374725","https://openalex.org/W3092497455","https://openalex.org/W3206319754","https://openalex.org/W4206046172","https://openalex.org/W4206481149","https://openalex.org/W4206774749","https://openalex.org/W6755840435"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2358034992","https://openalex.org/W2367936931","https://openalex.org/W2351992004","https://openalex.org/W2380207131","https://openalex.org/W2383319832","https://openalex.org/W2030492936","https://openalex.org/W2372547243","https://openalex.org/W2352632909"],"abstract_inverted_index":{"The":[0,190],"impact":[1,48,153,201,229,251],"of":[2,15,49,103,109,112,124,178,202,228,230,235,252],"Euro":[3,35,50,113,231],"2012":[4,36,51,232],"on":[5,52,59,96,160,166,182,195,207,256],"employment":[6,61,75,208,239],"and":[7,62,76,209,240],"wages":[8,78,210],"in":[9,37,56,74,79,138,170,211,222,233,238,245],"Poland":[10,223],"IntroductionThis":[11],"study,":[12,172],"as":[13],"one":[14],"the":[16,20,34,47,53,60,66,72,80,83,90,98,101,104,110,115,122,125,131,135,148,152,161,175,179,200,203,212,217,226,250,257,265],"few":[17],"concerned":[18,224],"with":[19,225],"Polish":[21,38,183],"circumstances,":[22],"is":[23,128,216,248],"intended":[24],"to":[25,32,45,89,106,147,150,173,198],"determine":[26,46,151,199],"what":[27],"significance":[28],"should":[29,260],"be":[30,144,261],"attributed":[31],"stage":[33],"host":[39,214],"cities.The":[40],"study":[41,132,221],"contains":[42],"an":[43,196],"attempt":[44,197],"labour":[54,162,258],"market":[55,163,259],"Poland,":[57],"specifically":[58],"wages.For":[63],"this":[64,171,186],"purpose":[65],"differences-in-differences":[67],"model":[68],"was":[69,94],"applied,":[70],"investigating":[71],"changes":[73,236],"real":[77],"voivodeships":[81],"where":[82],"tournament":[84],"matches":[85],"were":[86],"played":[87],"compared":[88],"other":[91,167],"voivodeships.Strong":[92],"emphasis":[93],"placed":[95],"analysing":[97],"situation":[99],"at":[100],"end":[102,123],"event":[105,126,255],"enable":[107],"determination":[108],"legacy":[111],"2012.Despite":[114],"relatively":[116],"short":[117],"period":[118],"that":[119,130,249],"elapsed":[120],"since":[121],"it":[127,142],"hoped":[129],"will":[133,143],"show":[134],"anticipated":[136],"trends.Nevertheless,":[137],"more":[139],"distant":[140],"future":[141],"worth":[145],"returning":[146],"attempts":[149],"by":[154,185,263],"ex":[155,219],"post":[156,220],"analysis,":[157],"not":[158],"only":[159],"but":[164],"also":[165],"areas":[168],"indicated":[169],"obtain":[174],"full":[176],"picture":[177],"effect":[180],"exerted":[181],"cities":[184],"mega":[187],"sports":[188,254],"event.":[189],"research":[191],"methodologyThis":[192],"chapter":[193],"focuses":[194],"UEFA":[204],"European":[205],"Championships":[206],"four":[213],"cities.It":[215],"first":[218],"degree":[227],"terms":[234],"both":[237],"wages.The":[241],"view":[242],"commonly":[243],"expressed":[244],"world":[246],"literature":[247],"a":[253],"investigated":[262],"determining":[264]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}