{"id":"https://openalex.org/W4408238695","doi":"https://doi.org/10.3389/fdgth.2025.1516600","title":"Effect of a digital blood pressure coach on hypertension management in primary care practices\u2014a pragmatic, randomised controlled trial","display_name":"Effect of a digital blood pressure coach on hypertension management in primary care practices\u2014a pragmatic, randomised controlled trial","publication_year":2025,"publication_date":"2025-03-07","ids":{"openalex":"https://openalex.org/W4408238695","doi":"https://doi.org/10.3389/fdgth.2025.1516600","pmid":"https://pubmed.ncbi.nlm.nih.gov/40124106"},"language":"en","primary_location":{"id":"doi:10.3389/fdgth.2025.1516600","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2025.1516600","pdf_url":"https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2025.1516600/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Digital Health","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2025.1516600/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086198649","display_name":"Christian Beger","orcid":"https://orcid.org/0000-0002-4701-2135"},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Beger","raw_affiliation_strings":["Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","Vascular Medicine Research, Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]},{"raw_affiliation_string":"Vascular Medicine Research, Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087889197","display_name":"Dominik R\u00fcegger","orcid":"https://orcid.org/0000-0001-5924-6759"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dominik R\u00fcegger","raw_affiliation_strings":["Pathmate Technologies GmbH, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathmate Technologies GmbH, Mannheim, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085747025","display_name":"Anna Lenz","orcid":"https://orcid.org/0009-0003-8451-4745"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Lenz","raw_affiliation_strings":["Pathmate Technologies GmbH, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathmate Technologies GmbH, Mannheim, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052062410","display_name":"Steffen Wagner","orcid":"https://orcid.org/0000-0003-0873-1601"},"institutions":[{"id":"https://openalex.org/I129643931","display_name":"Berliner Hochschule f\u00fcr Technik","ror":"https://ror.org/00w7whj55","country_code":"DE","type":"education","lineage":["https://openalex.org/I129643931"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Wagner","raw_affiliation_strings":["Department II (Mathematics, Physics and Chemistry), Berliner Hochschule f\u00fcr Technik, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department II (Mathematics, Physics and Chemistry), Berliner Hochschule f\u00fcr Technik, Berlin, Germany","institution_ids":["https://openalex.org/I129643931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085792074","display_name":"Kai M. Schmidt\u2010Ott","orcid":"https://orcid.org/0000-0002-7700-7142"},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kai Martin Schmidt-Ott","raw_affiliation_strings":["Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086933795","display_name":"Dirk Volland","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dirk Volland","raw_affiliation_strings":["Pathmate Technologies GmbH, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathmate Technologies GmbH, Mannheim, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006913044","display_name":"Florian P. Limbourg","orcid":"https://orcid.org/0000-0002-8313-7226"},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Florian P. Limbourg","raw_affiliation_strings":["Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","Vascular Medicine Research, Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]},{"raw_affiliation_string":"Vascular Medicine Research, Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5006913044"],"corresponding_institution_ids":["https://openalex.org/I34809795"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":11.4788,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.98116021,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"7","issue":null,"first_page":"1516600","last_page":"1516600"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.8346999883651733,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.8346999883651733,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.1006999984383583,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10912","display_name":"Telemedicine and Telehealth Implementation","score":0.012400000356137753,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7846367359161377},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.7276260852813721},{"id":"https://openalex.org/keywords/randomized-controlled-trial","display_name":"Randomized controlled trial","score":0.6737880706787109},{"id":"https://openalex.org/keywords/guideline","display_name":"Guideline","score":0.6079564094543457},{"id":"https://openalex.org/keywords/physical-therapy","display_name":"Physical therapy","score":0.5541401505470276},{"id":"https://openalex.org/keywords/intervention","display_name":"Intervention (counseling)","score":0.46206602454185486},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3131692409515381},{"id":"https://openalex.org/keywords/nursing","display_name":"Nursing","score":0.1965036392211914}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7846367359161377},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7276260852813721},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6737880706787109},{"id":"https://openalex.org/C2780182762","wikidata":"https://www.wikidata.org/wiki/Q1630279","display_name":"Guideline","level":2,"score":0.6079564094543457},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5541401505470276},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.46206602454185486},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3131692409515381},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.1965036392211914},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fdgth.2025.1516600","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2025.1516600","pdf_url":"https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2025.1516600/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Digital Health","raw_type":"journal-article"},{"id":"pmid:40124106","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40124106","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in digital health","raw_type":null},{"id":"pmh:oai:doaj.org/article:a4e8ccdeb74b4bd1b73a8be933bd907d","is_oa":true,"landing_page_url":"https://doaj.org/article/a4e8ccdeb74b4bd1b73a8be933bd907d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Digital Health, Vol 7 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11925922","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11925922","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Digit Health","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fdgth.2025.1516600","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2025.1516600","pdf_url":"https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2025.1516600/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Digital Health","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7900000214576721,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4408238695.pdf"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1951724000","https://openalex.org/W1989049247","https://openalex.org/W1997118573","https://openalex.org/W2107026277","https://openalex.org/W2169428949","https://openalex.org/W2271727878","https://openalex.org/W2754672704","https://openalex.org/W2789104451","https://openalex.org/W2799837895","https://openalex.org/W2809123291","https://openalex.org/W2809923763","https://openalex.org/W3010492903","https://openalex.org/W3016356891","https://openalex.org/W3048383434","https://openalex.org/W3086532707","https://openalex.org/W3157857666","https://openalex.org/W3181754241","https://openalex.org/W3198531566","https://openalex.org/W4239096779","https://openalex.org/W4285055565","https://openalex.org/W4308490348","https://openalex.org/W4315928593","https://openalex.org/W4362623048","https://openalex.org/W4381598483"],"related_works":["https://openalex.org/W2339422290","https://openalex.org/W2397653702","https://openalex.org/W3019157102","https://openalex.org/W4233871529","https://openalex.org/W2338818750","https://openalex.org/W2365451219","https://openalex.org/W2415869793","https://openalex.org/W4211072166","https://openalex.org/W28723353","https://openalex.org/W4231104876"],"abstract_inverted_index":{"Importance":[0],"Smartphone":[1],"medical":[2],"applications":[3],"(apps)":[4],"may":[5,359],"improve":[6],"blood":[7,161],"pressure":[8,162],"(BP)":[9],"control":[10,156,187,240,268,302],"in":[11,16,32,36,72,138,150,203,226,238,257,266,290,300,324,330,350],"the":[12,38,96,119,122,186,192,204,227,239,258,267,284,291,301,362],"primary":[13,24,33,128,325],"care":[14,25,34,326],"setting":[15],"patients":[17,60],"with":[18,59,61,74,140,214,270,317],"hypertension.":[19],"However,":[20],"real-world":[21],"evidence":[22],"from":[23,83,170],"is":[26],"largely":[27],"lacking.":[28],"Objective":[29],"To":[30],"analyse,":[31],"practices":[35,71,173,358],"Germany,":[37,73],"effect":[39],"of":[40,50,64,78,121,167,201,222,275,288,365],"a":[41,62,75,99,218,271,295],"smartphone":[42,100],"app":[43,323],"on":[44],"systolic":[45,132,151,331],"BP":[46,105,133,155,332,338],"compared":[47,297,340],"to":[48,86,95,159,185,191,253,262,298,321,336,341],"standard":[49,113,342],"care.":[51,343],"Design":[52],"A":[53,165],"pragmatic,":[54],"non-blinded":[55],"randomized":[56,320],"controlled":[57],"trial":[58],"diagnosis":[63],"hypertension":[65,117,142,216,319,351],"was":[66,130,207],"conducted":[67],"across":[68,357],"23":[69,171],"general":[70,172],"follow-up":[76,285],"period":[77],"3":[79],"months.":[80],"Recruitment":[81],"occurred":[82],"January":[84],"2022":[85],"May":[87],"2023.":[88],"Intervention":[89],"The":[90,127,197],"intervention":[91,193,205,228,259,292,367],"group":[92,188,194,206,229,241,260,293,303],"received":[93,112],"access":[94],"Manoa":[97],"app,":[98],"coach":[101],"integrating":[102],"guideline-compliant":[103],"home":[104,160,337],"monitoring":[106,339],"and":[107,152,157,179,189,234,261,314,354],"lifestyle-coaching.":[108],"All":[109],"study":[110],"participants":[111,139,169,182,202,213,289],"treatment":[114],"for":[115,195],"arterial":[116],"at":[118],"discretion":[120],"treating":[123],"physician.":[124],"Main":[125],"Outcomes":[126],"outcome":[129],"office":[131],"(oSBP)":[134],"after":[135,176],"90\u2013150":[136],"days":[137],"uncontrolled":[141,215,318],"(oSBP":[143],"\u2265140":[144],"mmHg).":[145],"Secondary":[146],"outcomes":[147],"included":[148],"changes":[149],"diastolic":[153],"BP,":[154],"adherence":[158,335],"monitoring.":[163],"Results":[164],"total":[166],"606":[168],"were":[174,183],"randomized,":[175],"data":[177],"clearance":[178],"review,":[180],"249":[181],"assigned":[184],"259":[190],"analysis.":[196],"mean":[198,219,273],"age":[199],"(SD)":[200,221],"55.9":[208],"(12.9)":[209],"years.":[210],"At":[211,283],"baseline,":[212],"had":[217],"oSBP":[220,251],"152.6":[223,235],"(14.2)":[224],"mmHg":[225,237,256,265,277],"(":[230,242],"n":[231,243],"=":[232,244,305,311],"162)":[233],"(14.1)":[236],"147).":[245],"After":[246],"120":[247],"\u00b1":[248],"14":[249],"days,":[250],"decreased":[252],"137.4":[254],"(14.4)":[255],"137.7":[263],"(14.5)":[264],"group,":[269],"between-group":[272],"difference":[274],"\u22120.2":[276],"[95%":[278],"CI":[279,308],"(\u22123.9,3.5);":[280],"P":[281,310],"=.9].":[282],"appointment,":[286],"69.1%":[287],"submitted":[294],"BP-diary,":[296],"36.1%":[299],"[OR":[304],"3.95;":[306],"95%":[307],"(2.73,5.72);":[309],"&amp;lt;0.001].":[312],"Conclusions":[313],"Relevance":[315],"Participants":[316],"an":[322],"achieved":[327],"similar":[328],"decreases":[329],"but":[333],"higher":[334],"In":[344],"this":[345],"open-label,":[346],"pragmatic":[347],"trial,":[348],"variability":[349],"management":[352],"strategies":[353],"limited":[355],"standardization":[356],"have":[360],"confounded":[361],"precise":[363],"evaluation":[364],"digital":[366],"benefits.":[368],"Clinical":[369],"Trial":[370],"Registration":[371],"ClinicalTrials.gov":[372],",":[373],"identifier,":[374],"(DRKS00027964)":[375]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}
