{"id":"https://openalex.org/W4378087331","doi":"https://doi.org/10.3389/fdgth.2023.1062471","title":"A CBT-based mobile intervention as an adjunct treatment for adolescents with symptoms of depression: a virtual randomized controlled feasibility trial","display_name":"A CBT-based mobile intervention as an adjunct treatment for adolescents with symptoms of depression: a virtual randomized controlled feasibility trial","publication_year":2023,"publication_date":"2023-05-23","ids":{"openalex":"https://openalex.org/W4378087331","doi":"https://doi.org/10.3389/fdgth.2023.1062471","pmid":"https://pubmed.ncbi.nlm.nih.gov/37323125"},"language":"en","primary_location":{"id":"doi:10.3389/fdgth.2023.1062471","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2023.1062471","pdf_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2023.1062471/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Digital Health","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2023.1062471/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003663656","display_name":"Vera Kulikov","orcid":"https://orcid.org/0000-0001-6598-3843"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vera N. Kulikov","raw_affiliation_strings":["Research Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092014256","display_name":"Phoebe C. Crosthwaite","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Phoebe C. Crosthwaite","raw_affiliation_strings":["Research Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019280283","display_name":"Shana A. Hall","orcid":"https://orcid.org/0000-0001-9686-8549"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Shana A. Hall","raw_affiliation_strings":["Research Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007834870","display_name":"Jessica Flannery","orcid":"https://orcid.org/0000-0003-0710-2512"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jessica E. Flannery","raw_affiliation_strings":["Science Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Science Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032406825","display_name":"Gabriel Strauss","orcid":"https://orcid.org/0009-0006-3960-8760"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriel S. Strauss","raw_affiliation_strings":["Product Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Product Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025083950","display_name":"Elise Vierra","orcid":"https://orcid.org/0009-0001-2062-4668"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elise M. Vierra","raw_affiliation_strings":["Content Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Content Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027721501","display_name":"Xin Koepsell","orcid":"https://orcid.org/0009-0000-5442-9636"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xin L. Koepsell","raw_affiliation_strings":["Content Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Content Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031291496","display_name":"Jessica I. Lake","orcid":"https://orcid.org/0000-0003-0682-8725"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jessica I. Lake","raw_affiliation_strings":["Science Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Science Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005543513","display_name":"Aarthi Padmanabhan","orcid":"https://orcid.org/0000-0002-3727-5468"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aarthi Padmanabhan","raw_affiliation_strings":["Research Department, Limbix Health, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department, Limbix Health, San Francisco, CA, United States","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5019280283","https://openalex.org/A5031291496"],"corresponding_institution_ids":[],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":4.6111,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.95593108,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"5","issue":null,"first_page":"1062471","last_page":"1062471"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/randomized-controlled-trial","display_name":"Randomized controlled trial","score":0.6937637329101562},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5976773500442505},{"id":"https://openalex.org/keywords/depression","display_name":"Depression (economics)","score":0.5502136945724487},{"id":"https://openalex.org/keywords/intervention","display_name":"Intervention (counseling)","score":0.47469204664230347},{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"Cognitive behavioral therapy","score":0.4483201205730438},{"id":"https://openalex.org/keywords/mhealth","display_name":"mHealth","score":0.42007747292518616},{"id":"https://openalex.org/keywords/physical-therapy","display_name":"Physical therapy","score":0.37927311658859253},{"id":"https://openalex.org/keywords/clinical-psychology","display_name":"Clinical psychology","score":0.37500929832458496},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.29035836458206177},{"id":"https://openalex.org/keywords/psychological-intervention","display_name":"Psychological intervention","score":0.2259979546070099},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.17326512932777405}],"concepts":[{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6937637329101562},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5976773500442505},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5502136945724487},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.47469204664230347},{"id":"https://openalex.org/C2781265626","wikidata":"https://www.wikidata.org/wiki/Q1147152","display_name":"Cognitive behavioral therapy","level":3,"score":0.4483201205730438},{"id":"https://openalex.org/C2779363104","wikidata":"https://www.wikidata.org/wiki/Q17069079","display_name":"mHealth","level":3,"score":0.42007747292518616},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.37927311658859253},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.37500929832458496},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.29035836458206177},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.2259979546070099},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17326512932777405},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fdgth.2023.1062471","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2023.1062471","pdf_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2023.1062471/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Digital Health","raw_type":"journal-article"},{"id":"pmid:37323125","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37323125","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in digital health","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10262850","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10262850","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10262850/pdf/fdgth-05-1062471.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Digit Health","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:47f29515b1534bdabe712481b900b442","is_oa":true,"landing_page_url":"https://doaj.org/article/47f29515b1534bdabe712481b900b442","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Digital Health, Vol 5 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fdgth.2023.1062471","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fdgth.2023.1062471","pdf_url":"https://www.frontiersin.org/articles/10.3389/fdgth.2023.1062471/pdf","source":{"id":"https://openalex.org/S4210170686","display_name":"Frontiers in Digital Health","issn_l":"2673-253X","issn":["2673-253X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Digital Health","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8299999833106995,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4378087331.pdf"},"referenced_works_count":90,"referenced_works":["https://openalex.org/W591743112","https://openalex.org/W1519727848","https://openalex.org/W1583848026","https://openalex.org/W1965036930","https://openalex.org/W1967494979","https://openalex.org/W1975937207","https://openalex.org/W1985542720","https://openalex.org/W1985645068","https://openalex.org/W1986166461","https://openalex.org/W2011557538","https://openalex.org/W2017824397","https://openalex.org/W2018957295","https://openalex.org/W2019391304","https://openalex.org/W2025113055","https://openalex.org/W2026805460","https://openalex.org/W2032191478","https://openalex.org/W2033442056","https://openalex.org/W2048533792","https://openalex.org/W2049265876","https://openalex.org/W2051593711","https://openalex.org/W2055218553","https://openalex.org/W2055937548","https://openalex.org/W2071672619","https://openalex.org/W2072661057","https://openalex.org/W2078254424","https://openalex.org/W2078965693","https://openalex.org/W2079659815","https://openalex.org/W2082494913","https://openalex.org/W2092700691","https://openalex.org/W2095856855","https://openalex.org/W2099333672","https://openalex.org/W2100661708","https://openalex.org/W2102797406","https://openalex.org/W2109751525","https://openalex.org/W2112086039","https://openalex.org/W2114714768","https://openalex.org/W2123440047","https://openalex.org/W2130503031","https://openalex.org/W2132322340","https://openalex.org/W2137928281","https://openalex.org/W2138073576","https://openalex.org/W2143280830","https://openalex.org/W2147085624","https://openalex.org/W2149314258","https://openalex.org/W2152212215","https://openalex.org/W2152802023","https://openalex.org/W2157037135","https://openalex.org/W2165665875","https://openalex.org/W2187337315","https://openalex.org/W2188745674","https://openalex.org/W2282934196","https://openalex.org/W2341987087","https://openalex.org/W2345859514","https://openalex.org/W2346033637","https://openalex.org/W2397812290","https://openalex.org/W2582551920","https://openalex.org/W2597330569","https://openalex.org/W2623779865","https://openalex.org/W2740734470","https://openalex.org/W2766236516","https://openalex.org/W2766960207","https://openalex.org/W2782898451","https://openalex.org/W2784244485","https://openalex.org/W2789816271","https://openalex.org/W2791527759","https://openalex.org/W2893135082","https://openalex.org/W2913551388","https://openalex.org/W2921393753","https://openalex.org/W2926589548","https://openalex.org/W2942118272","https://openalex.org/W2963232155","https://openalex.org/W2971542115","https://openalex.org/W2989270862","https://openalex.org/W3009856614","https://openalex.org/W3010314022","https://openalex.org/W3027708473","https://openalex.org/W3035590377","https://openalex.org/W3080922995","https://openalex.org/W3087421527","https://openalex.org/W3129291866","https://openalex.org/W3164742078","https://openalex.org/W3183266754","https://openalex.org/W3190876559","https://openalex.org/W3195929293","https://openalex.org/W4234297249","https://openalex.org/W4240142581","https://openalex.org/W4292712444","https://openalex.org/W4295927571","https://openalex.org/W4306992901","https://openalex.org/W6600808634"],"related_works":["https://openalex.org/W3176210869","https://openalex.org/W3157260717","https://openalex.org/W1989929201","https://openalex.org/W2963498005","https://openalex.org/W2328171598","https://openalex.org/W4210372979","https://openalex.org/W4254922057","https://openalex.org/W4318480255","https://openalex.org/W2773392333","https://openalex.org/W2735645867"],"abstract_inverted_index":{"Background:":[0],"High":[1],"rates":[2,141],"of":[3,26,74,176],"adolescent":[4],"depression":[5,52,65,180],"demand":[6],"for":[7,49,102,117,207],"more":[8],"effective,":[9],"accessible":[10],"treatment":[11,48],"options.":[12],"A":[13],"virtual":[14],"randomized":[15],"controlled":[16],"trial":[17],"was":[18,100,156],"used":[19],"to":[20,38,160],"assess":[21],"the":[22,54,62,75,95,126],"feasibility":[23,144,202],"and":[24,70,82,139,170,185,194,215],"acceptability":[25],"a":[27,39],"5-week,":[28],"self-guided,":[29],"cognitive":[30],"behavioral":[31],"therapy":[32],"(CBT)-based":[33],"mobile":[34,41],"application,":[35],"Spark,":[36],"compared":[37],"psychoeducational":[40],"application":[42],"(Active":[43],"Control)":[44],"as":[45],"an":[46],"adjunct":[47],"adolescents":[50],"with":[51],"during":[53,200],"COVID-19":[55],"pandemic.":[56],"Methods:":[57],"=":[58,92],"25).":[59],"Questionnaires,":[60],"including":[61],"PHQ-8":[63,99],"measuring":[64],"symptoms,":[66,79],"completed":[67],"before,":[68],"during,":[69],"immediately":[71],"following":[72],"completion":[73],"intervention,":[76],"evaluated":[77],"depressive":[78],"usability,":[80],"engagement,":[81],"participant":[83],"safety.":[84,216],"App":[85],"engagement":[86],"data":[87],"were":[88,115,130],"also":[89],"analyzed.":[90],"Results:":[91],".72)":[93],"though":[94],"numeric":[96],"decrease":[97],"in":[98,125,179],"greater":[101],"Spark":[103,118,155,184],"(4.69":[104],"vs.":[105],"3.56).":[106],"No":[107],"serious":[108,121],"adverse":[109,112,122,172],"events":[110,123],"or":[111,148],"device":[113],"effects":[114],"reported":[116,124],"users.":[119],"Two":[120],"Active":[127,186],"Control":[128,187],"group":[129],"addressed":[131],"per":[132],"our":[133],"safety":[134,166],"protocol.":[135],"Conclusion:":[136],"Recruitment,":[137],"enrollment,":[138],"retention":[140],"demonstrated":[142],"study":[143,192,195,203],"by":[145,191],"being":[146],"comparable":[147],"better":[149],"than":[150],"other":[151],"mental":[152],"health":[153],"apps.":[154],"highly":[157],"acceptable":[158],"relative":[159],"published":[161],"norms.":[162],"The":[163,174],"study's":[164],"novel":[165],"protocol":[167],"efficiently":[168],"detected":[169],"managed":[171],"events.":[173],"lack":[175],"significant":[177],"difference":[178],"symptom":[181],"reduction":[182],"between":[183],"may":[188],"be":[189,205],"explained":[190],"design":[193,196],"factors.":[197],"Procedures":[198],"established":[199],"this":[201],"will":[204],"leveraged":[206],"subsequent":[208],"powered":[209],"clinical":[210],"trials":[211],"evaluating":[212],"app":[213],"efficacy":[214],"Clinical":[217],"Trial":[218],"Registration:":[219],"https://clinicaltrials.gov/ct2/show/NCT04524598.":[220]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}
