{"id":"https://openalex.org/W7127591051","doi":"https://doi.org/10.3389/fbinf.2025.1721028","title":"Essential nucleic acid omics: a theoretical foundation for early-stage users","display_name":"Essential nucleic acid omics: a theoretical foundation for early-stage users","publication_year":2026,"publication_date":"2026-02-04","ids":{"openalex":"https://openalex.org/W7127591051","doi":"https://doi.org/10.3389/fbinf.2025.1721028","pmid":"https://pubmed.ncbi.nlm.nih.gov/41716218"},"language":"en","primary_location":{"id":"doi:10.3389/fbinf.2025.1721028","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1721028","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1721028/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://public-pages-files-2025.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1721028/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104184025","display_name":"Andrew J Maritan","orcid":null},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]},{"id":"https://openalex.org/I4210103014","display_name":"Max Planck Institute for Marine Microbiology","ror":"https://ror.org/02385fa51","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210103014"]}],"countries":["DE","US"],"is_corresponding":true,"raw_author_name":"Andrew J. Maritan","raw_affiliation_strings":["Max Planck Institute for Marine Microbiology","Montana State University, Department of Microbiology & Cell Biology"],"affiliations":[{"raw_affiliation_string":"Max Planck Institute for Marine Microbiology","institution_ids":["https://openalex.org/I4210103014"]},{"raw_affiliation_string":"Montana State University, Department of Microbiology & Cell Biology","institution_ids":["https://openalex.org/I23732399"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043222288","display_name":"Frank J. Stewart","orcid":"https://orcid.org/0000-0002-8139-5176"},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]},{"id":"https://openalex.org/I4210108440","display_name":"Biology of Infection","ror":"https://ror.org/01x3ftb23","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I4210098000","https://openalex.org/I4210108440"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Frank J. Stewart","raw_affiliation_strings":["Georgia Institute of Technology, School of Biological Sciences, Center for Microbial Dynamics and Infection","Montana State University, Department of Microbiology & Cell Biology"],"affiliations":[{"raw_affiliation_string":"Georgia Institute of Technology, School of Biological Sciences, Center for Microbial Dynamics and Infection","institution_ids":["https://openalex.org/I4210108440"]},{"raw_affiliation_string":"Montana State University, Department of Microbiology & Cell Biology","institution_ids":["https://openalex.org/I23732399"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5104184025"],"corresponding_institution_ids":["https://openalex.org/I23732399","https://openalex.org/I4210103014"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23984829,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":null,"first_page":"1721028","last_page":"1721028"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.36579999327659607,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.36579999327659607,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.09709999710321426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14427","display_name":"Environmental Monitoring and Data Management","score":0.06840000301599503,"subfield":{"id":"https://openalex.org/subfields/1907","display_name":"Geology"},"field":{"id":"https://openalex.org/fields/19","display_name":"Earth and Planetary Sciences"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/omics","display_name":"Omics","score":0.6638000011444092},{"id":"https://openalex.org/keywords/confusion","display_name":"Confusion","score":0.6205000281333923},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.47440001368522644},{"id":"https://openalex.org/keywords/terabyte","display_name":"Terabyte","score":0.3752000033855438},{"id":"https://openalex.org/keywords/foundation","display_name":"Foundation (evidence)","score":0.35100001096725464},{"id":"https://openalex.org/keywords/modular-design","display_name":"Modular design","score":0.334199994802475}],"concepts":[{"id":"https://openalex.org/C157585117","wikidata":"https://www.wikidata.org/wiki/Q158666","display_name":"Omics","level":2,"score":0.6638000011444092},{"id":"https://openalex.org/C2781140086","wikidata":"https://www.wikidata.org/wiki/Q557945","display_name":"Confusion","level":2,"score":0.6205000281333923},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.5776000022888184},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.47440001368522644},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4494999945163727},{"id":"https://openalex.org/C199683683","wikidata":"https://www.wikidata.org/wiki/Q8799","display_name":"Terabyte","level":2,"score":0.3752000033855438},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.37119999527931213},{"id":"https://openalex.org/C2780966255","wikidata":"https://www.wikidata.org/wiki/Q5474306","display_name":"Foundation (evidence)","level":2,"score":0.35100001096725464},{"id":"https://openalex.org/C101468663","wikidata":"https://www.wikidata.org/wiki/Q1620158","display_name":"Modular design","level":2,"score":0.334199994802475},{"id":"https://openalex.org/C2776372474","wikidata":"https://www.wikidata.org/wiki/Q508291","display_name":"Simplicity","level":2,"score":0.3197999894618988},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3176000118255615},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.3138999938964844},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.30399999022483826},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.28279998898506165},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.2635999917984009},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2549000084400177},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.25220000743865967}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fbinf.2025.1721028","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1721028","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1721028/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:41716218","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41716218","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:839851c305b74663bb6c2783f7afa5c9","is_oa":true,"landing_page_url":"https://doaj.org/article/839851c305b74663bb6c2783f7afa5c9","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioinformatics, Vol 5 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12913566","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12913566/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fbinf.2025.1721028","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1721028","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1721028/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life below water","score":0.6778144240379333,"id":"https://metadata.un.org/sdg/14"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7127591051.pdf","grobid_xml":"https://content.openalex.org/works/W7127591051.grobid-xml"},"referenced_works_count":223,"referenced_works":["https://openalex.org/W1481922934","https://openalex.org/W1676753599","https://openalex.org/W1791999417","https://openalex.org/W1832554097","https://openalex.org/W1925823522","https://openalex.org/W1936330011","https://openalex.org/W1958058086","https://openalex.org/W1965778443","https://openalex.org/W1970156673","https://openalex.org/W1971403296","https://openalex.org/W1984708728","https://openalex.org/W1985200777","https://openalex.org/W1988654243","https://openalex.org/W1998663222","https://openalex.org/W2001031283","https://openalex.org/W2004536197","https://openalex.org/W2006652125","https://openalex.org/W2007367248","https://openalex.org/W2015761904","https://openalex.org/W2016760914","https://openalex.org/W2019598963","https://openalex.org/W2023652460","https://openalex.org/W2036897871","https://openalex.org/W2043401730","https://openalex.org/W2045204781","https://openalex.org/W2050717506","https://openalex.org/W2055305007","https://openalex.org/W2064334669","https://openalex.org/W2068687524","https://openalex.org/W2069689025","https://openalex.org/W2072812562","https://openalex.org/W2077191430","https://openalex.org/W2094448442","https://openalex.org/W2096093282","https://openalex.org/W2098213808","https://openalex.org/W2098386120","https://openalex.org/W2102236737","https://openalex.org/W2103901746","https://openalex.org/W2104846587","https://openalex.org/W2107974372","https://openalex.org/W2109218242","https://openalex.org/W2109867978","https://openalex.org/W2112097237","https://openalex.org/W2112364185","https://openalex.org/W2112499642","https://openalex.org/W2114163760","https://openalex.org/W2114200698","https://openalex.org/W2114604152","https://openalex.org/W2116041602","https://openalex.org/W2124637227","https://openalex.org/W2125013165","https://openalex.org/W2126419817","https://openalex.org/W2126466006","https://openalex.org/W2127036970","https://openalex.org/W2127230663","https://openalex.org/W2135191113","https://openalex.org/W2138270253","https://openalex.org/W2138863122","https://openalex.org/W2140503409","https://openalex.org/W2141929300","https://openalex.org/W2142678478","https://openalex.org/W2143258005","https://openalex.org/W2143485490","https://openalex.org/W2145537580","https://openalex.org/W2149429041","https://openalex.org/W2153283265","https://openalex.org/W2157159562","https://openalex.org/W2166123725","https://openalex.org/W2167435540","https://openalex.org/W2168909179","https://openalex.org/W2170747616","https://openalex.org/W2175526948","https://openalex.org/W2179507357","https://openalex.org/W2302501749","https://openalex.org/W2315521535","https://openalex.org/W2412095308","https://openalex.org/W2466118811","https://openalex.org/W2513506562","https://openalex.org/W2520355709","https://openalex.org/W2533015169","https://openalex.org/W2574408351","https://openalex.org/W2586763669","https://openalex.org/W2605119622","https://openalex.org/W2611147605","https://openalex.org/W2736920791","https://openalex.org/W2745006471","https://openalex.org/W2753961085","https://openalex.org/W2766358903","https://openalex.org/W2766648600","https://openalex.org/W2767590279","https://openalex.org/W2769542288","https://openalex.org/W2789782083","https://openalex.org/W2797794199","https://openalex.org/W2805781739","https://openalex.org/W2883810717","https://openalex.org/W2885079199","https://openalex.org/W2885799866","https://openalex.org/W2887754912","https://openalex.org/W2889019390","https://openalex.org/W2918965813","https://openalex.org/W2934204669","https://openalex.org/W2939615846","https://openalex.org/W2949303487","https://openalex.org/W2950464960","https://openalex.org/W2950954328","https://openalex.org/W2951254987","https://openalex.org/W2952463830","https://openalex.org/W2952921381","https://openalex.org/W2963276645","https://openalex.org/W2985109597","https://openalex.org/W2991239467","https://openalex.org/W2996518130","https://openalex.org/W3005025658","https://openalex.org/W3005657716","https://openalex.org/W3006139292","https://openalex.org/W3006651537","https://openalex.org/W3018115558","https://openalex.org/W3019706413","https://openalex.org/W3025757981","https://openalex.org/W3025787433","https://openalex.org/W3025857586","https://openalex.org/W3028280407","https://openalex.org/W3033733359","https://openalex.org/W3036135788","https://openalex.org/W3090089243","https://openalex.org/W3104596207","https://openalex.org/W3114403576","https://openalex.org/W3125972683","https://openalex.org/W3129897473","https://openalex.org/W3135029012","https://openalex.org/W3137047737","https://openalex.org/W3137581305","https://openalex.org/W3161251590","https://openalex.org/W3177828909","https://openalex.org/W3196134494","https://openalex.org/W3199620625","https://openalex.org/W3200242814","https://openalex.org/W3207938624","https://openalex.org/W3210069677","https://openalex.org/W3216588755","https://openalex.org/W3217463608","https://openalex.org/W4205652189","https://openalex.org/W4206546384","https://openalex.org/W4207058499","https://openalex.org/W4213265720","https://openalex.org/W4213387068","https://openalex.org/W4220887372","https://openalex.org/W4220951604","https://openalex.org/W4220999759","https://openalex.org/W4221000288","https://openalex.org/W4224250125","https://openalex.org/W4225661102","https://openalex.org/W4226301365","https://openalex.org/W4239833133","https://openalex.org/W4242673342","https://openalex.org/W4283644865","https://openalex.org/W4293088719","https://openalex.org/W4304481015","https://openalex.org/W4310157184","https://openalex.org/W4310266409","https://openalex.org/W4312183813","https://openalex.org/W4317390266","https://openalex.org/W4317521200","https://openalex.org/W4318033791","https://openalex.org/W4318225016","https://openalex.org/W4322422933","https://openalex.org/W4323050312","https://openalex.org/W4327813710","https://openalex.org/W4380422445","https://openalex.org/W4380684571","https://openalex.org/W4382181649","https://openalex.org/W4382182288","https://openalex.org/W4382248980","https://openalex.org/W4384341779","https://openalex.org/W4385302529","https://openalex.org/W4385897613","https://openalex.org/W4387058357","https://openalex.org/W4387705462","https://openalex.org/W4388928506","https://openalex.org/W4389559403","https://openalex.org/W4390947644","https://openalex.org/W4391819368","https://openalex.org/W4392284169","https://openalex.org/W4392304066","https://openalex.org/W4392757294","https://openalex.org/W4392978714","https://openalex.org/W4393355062","https://openalex.org/W4393870943","https://openalex.org/W4393995158","https://openalex.org/W4394581382","https://openalex.org/W4394987863","https://openalex.org/W4396760077","https://openalex.org/W4396940192","https://openalex.org/W4398183095","https://openalex.org/W4399368495","https://openalex.org/W4400934521","https://openalex.org/W4401008249","https://openalex.org/W4401987108","https://openalex.org/W4402316320","https://openalex.org/W4402458841","https://openalex.org/W4402622583","https://openalex.org/W4402857717","https://openalex.org/W4403089974","https://openalex.org/W4403219214","https://openalex.org/W4404005707","https://openalex.org/W4404210264","https://openalex.org/W4404434589","https://openalex.org/W4404458588","https://openalex.org/W4404511392","https://openalex.org/W4406321761","https://openalex.org/W4407092397","https://openalex.org/W4407732971","https://openalex.org/W4408507120","https://openalex.org/W4409229284","https://openalex.org/W4410105705","https://openalex.org/W4410974032","https://openalex.org/W4411134777","https://openalex.org/W4411497601","https://openalex.org/W4412470469","https://openalex.org/W4412651422","https://openalex.org/W4412872011","https://openalex.org/W4414007742","https://openalex.org/W4414531246"],"related_works":[],"abstract_inverted_index":{"Modern":[0],"biology":[1],"often":[2],"relies":[3],"on":[4],"the":[5,82,122,129,182],"analysis":[6,156],"of":[7,10,15,54,74,89,95,106,112,125,131,170],"entire":[8],"sets":[9],"molecules":[11],"(omics).":[12],"A":[13],"subset":[14],"omics":[16,55,126,143,172,193,197],"uses":[17],"nucleic":[18],"acid":[19],"sequencing":[20,45],"to":[21,43,58,120,180],"reconstruct":[22],"genomes":[23],"and":[24,30,47,61,92,114,176],"profile":[25],"gene":[26],"expression.":[27],"Novel":[28],"findings":[29],"existing":[31],"data":[32,91],"are":[33,76,85],"contextualized":[34],"by":[35,188],"databases,":[36],"which":[37],"have":[38],"been":[39],"growing":[40],"exponentially":[41],"due":[42],"falling":[44],"costs":[46],"increased":[48],"computing":[49,80,97],"access.":[50],"The":[51],"increasing":[52],"accessibility":[53],"has":[56],"led":[57],"rapid":[59],"adoption":[60],"widespread":[62],"self-training":[63],"via":[64],"open-access":[65],"tools.":[66],"In":[67],"this":[68,135],"training":[69,191],"environment":[70],"new":[71],"users":[72],"(many":[73],"whom":[75],"students":[77],"also":[78],"applying":[79],"for":[81,202],"first":[83],"time)":[84],"confronted":[86],"with":[87,159],"Terabytes":[88],"sequence":[90],"an":[93,109],"ocean":[94],"topic-specific":[96],"guides":[98],"(often":[99],"directed":[100],"at":[101],"high-level":[102],"users).":[103],"This":[104,147,184],"flood":[105],"information":[107],"creates":[108],"initial":[110],"barrier":[111],"confusion":[113,136],"frustration,":[115],"where":[116,154,195],"it":[117],"is":[118,137,186],"challenging":[119],"identify":[121,167],"overarching":[123],"goals":[124],"analyses":[127],"through":[128],"details":[130],"computing.":[132],"We":[133],"believe":[134],"understandable":[138],"but":[139],"not":[140],"pre-destined,":[141],"as":[142],"is-at":[144],"its":[145,151],"core-simple.":[146],"simplicity":[148],"comes":[149],"from":[150],"modular":[152],"nature,":[153],"any":[155],"requires":[157],"familiarity":[158],"only":[160],"a":[161,200],"few":[162],"consistent":[163],"steps.":[164],"Here,":[165],"we":[166],"core":[168],"elements":[169],"all":[171],"analyses-data":[173],"products,":[174],"tools,":[175],"workflows-using":[177],"microbiology":[178],"applications":[179],"ground":[181],"discussion.":[183],"structure":[185],"informed":[187],"first-hand":[189],"experience":[190],"early-stage":[192],"users,":[194],"covering":[196],"theory":[198],"provides":[199],"foundation":[201],"practical":[203],"implementation.":[204]},"counts_by_year":[],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2026-02-06T00:00:00"}